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{"sheet":"Overview","index":0,"n_rows":16301,"n_cols":8,"rows_kept":4500,"cut":true,"hidden":false,"merged":[],"bounds":{"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0}}
["Overview - AOP ",null,null,{"$f":"(HYPERLINK(\"https://aopwiki.org/aops/40\",\"aop 40\"))","v":"aop 40"}]
["Skin Sensitisation AOP"]
["MeSH Chemical Name (hyperlinked)","ChemName","chemuid","1_MIE","2_KE","3_KE","4_KE","5_AO"]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4,B4)","v":"Latex"},"Latex","D007840",23,3,12,8,821]
["Rubber","Rubber","D012408",6,0,11,3,787]
["Formaldehyde","Formaldehyde","D005557",59,16,35,63,521]
["Tretinoin","Tretinoin","D014212",306,519,221,360,458]
["Dust","Dust","D004391",8,6,52,66,447]
["4-phenylenediamine","4-phenylenediamine","C029728",5,26,13,24,432]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755",144,195,39,657,301]
["rosin","rosin","C013893",0,0,2,3,292]
["2-methyl-4-isothiazolin-3-one","2-methyl-4-isothiazolin-3-one","C011506",2,6,3,15,280]
["Sodium Dodecyl Sulfate","Sodium Dodecyl Sulfate","D012967",162,79,20,10,280]
["Lidocaine","Lidocaine","D008012",102,18,11,38,279]
["Heparin","Heparin","D006493",1353,36,88,120,278]
["Dinitrochlorobenzene","Dinitrochlorobenzene","D004137",3,15,59,70,269]
["Carbamazepine","Carbamazepine","D002220",93,4,2,39,257]
["Vitamin A","Vitamin A","D014801",224,65,64,119,229]
["Ampicillin","Ampicillin","D000667",50,0,11,8,222]
["Water","Water","D014867",661,55,18,36,214]
["Fluorouracil","Fluorouracil","D005472",57,31,43,108,212]
["Amoxicillin","Amoxicillin","D000658",9,0,8,24,211]
["lawsone","lawsone","C005090",0,4,0,0,211]
["5-chloro-2-methyl-4-isothiazolin-3-one","5-chloro-2-methyl-4-isothiazolin-3-one","C011421",3,6,3,0,201]
["Nitric Oxide","Nitric Oxide","D009569",556,136,138,455,200]
["Methotrexate","Methotrexate","D008727",203,42,35,339,197]
["BCG Vaccine","BCG Vaccine","D001500",4,1,152,683,193]
["Chlorhexidine","Chlorhexidine","D002710",11,19,0,1,191]
["Dental Amalgam","Dental Amalgam","D003723",2,10,2,31,186]
["Ethanol","Ethanol","D000431",272,47,97,343,185]
["Aspirin","Aspirin","D001241",176,7,48,91,184]
["Budesonide","Budesonide","D019819",4,4,8,39,174]
["Hyaluronic Acid","Hyaluronic Acid","D006820",316,224,60,88,174]
["Urea","Urea","D014508",300,7,29,33,173]
["Thimerosal","Thimerosal","D013849",8,0,20,23,168]
["Calcitriol","Calcitriol","D002117",182,552,163,405,167]
["Doxorubicin","Doxorubicin","D004317",188,52,49,203,167]
["Acetaminophen","Acetaminophen","D000082",148,3,2,24,164]
["Neomycin","Neomycin","D009355",28,3,4,3,164]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411",0,0,0,0,155]
["Trimethoprim, Sulfamethoxazole Drug Combination","Trimethoprim, Sulfamethoxazole Drug Combination","D015662",17,3,3,38,155]
["Tobacco Smoke Pollution","Tobacco Smoke Pollution","D014028",0,14,12,43,154]
["Betamethasone","Betamethasone","D001623",8,28,9,43,153]
["Phenytoin","Phenytoin","D010672",365,12,9,78,153]
["Tacrolimus","Tacrolimus","D016559",102,91,104,948,153]
["Capsaicin","Capsaicin","D002211",42,31,8,47,152]
["Kathon 886","Kathon 886","C037057",0,0,0,0,151]
["Prednisolone","Prednisolone","D011239",115,11,49,227,150]
["Serotonin","Serotonin","D012701",640,17,62,148,148]
["Allopurinol","Allopurinol","D000493",8,7,3,12,146]
["sorafenib","sorafenib","C471405",16,19,18,39,145]
["Vitamin D","Vitamin D","D014807",204,161,128,187,144]
["Imatinib Mesylate","Imatinib Mesylate","D000068877",71,6,60,136,141]
["Anthralin","Anthralin","D000875",0,85,3,21,140]
["Ascorbic Acid","Ascorbic Acid","D001205",124,144,29,122,137]
["Thiourea","Thiourea","D013890",63,0,3,15,134]
["Chlorpromazine","Chlorpromazine","D002746",94,6,5,24,131]
["Benzoyl Peroxide","Benzoyl Peroxide","D001585",0,19,0,0,130]
["Diclofenac","Diclofenac","D004008",67,14,3,17,130]
["Erlotinib Hydrochloride","Erlotinib Hydrochloride","D000069347",18,7,1,4,129]
["Isotretinoin","Isotretinoin","D015474",3,17,3,31,128]
["Vitamin E","Vitamin E","D014810",45,60,13,188,127]
["calcipotriene","calcipotriene","C055085",4,109,18,28,119]
["Cetirizine","Cetirizine","D017332",7,14,2,16,119]
["Ketoprofen","Ketoprofen","D007660",44,10,0,1,119]
["Petroleum","Petroleum","D010578",1,4,5,19,117]
["Povidone-Iodine","Povidone-Iodine","D011206",1,19,1,0,117]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C68,B68)","v":"Methoxsalen"},"Methoxsalen","D008730",25,31,11,64,114]
["Minocycline","Minocycline","D008911",20,12,11,57,114]
["lamotrigine","lamotrigine","C047781",5,2,0,1,113]
["Paclitaxel","Paclitaxel","D017239",164,12,42,91,113]
["Clobetasol","Clobetasol","D002990",0,8,9,9,112]
["Chloramphenicol","Chloramphenicol","D002701",90,4,15,10,111]
["Piroxicam","Piroxicam","D010894",42,1,0,6,109]
["Epinephrine","Epinephrine","D004837",75,10,18,65,108]
["Potassium Dichromate","Potassium Dichromate","D011192",1,4,0,0,108]
["Warfarin","Warfarin","D014859",349,0,4,17,108]
["Dinitrofluorobenzene","Dinitrofluorobenzene","D004139",21,11,30,68,106]
["Dexamethasone","Dexamethasone","D003907",241,51,217,991,105]
["Heparin, Low-Molecular-Weight","Heparin, Low-Molecular-Weight","D006495",46,0,3,8,103]
["Ibuprofen","Ibuprofen","D007052",94,10,2,16,102]
["Isoniazid","Isoniazid","D007538",51,0,1,36,102]
["Dimethyl Sulfoxide","Dimethyl Sulfoxide","D004121",53,15,6,39,100]
["Hydroxyurea","Hydroxyurea","D006918",22,0,2,72,100]
["Methylprednisolone","Methylprednisolone","D008775",16,7,32,269,100]
["Triamcinolone Acetonide","Triamcinolone Acetonide","D014222",28,0,3,22,100]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861",264,180,19,149,99]
["Mechlorethamine","Mechlorethamine","D008466",18,12,5,19,98]
["terbinafine","terbinafine","C041359",3,4,0,0,96]
["imiquimod","imiquimod","C056493",1,85,100,66,95]
["Prilocaine","Prilocaine","D011318",3,6,0,0,95]
["Propylene Glycol","Propylene Glycol","D019946",2,0,0,0,94]
["Sulfasalazine","Sulfasalazine","D012460",12,0,9,61,94]
["Thiram","Thiram","D013893",2,0,0,4,94]
["Tuberculin","Tuberculin","D014373",7,0,79,209,94]
["Clonidine","Clonidine","D003000",16,1,1,4,93]
["Norepinephrine","Norepinephrine","D009638",138,4,16,77,93]
["Metronidazole","Metronidazole","D008795",17,3,0,18,92]
["Phenylephrine","Phenylephrine","D010656",10,0,0,6,92]
["Betaine","Betaine","D001622",30,9,0,6,91]
["docetaxel","docetaxel","C067311",22,4,19,29,91]
["ethylenediamine","ethylenediamine","C031234",2,0,0,0,91]
["Platelet Activating Factor","Platelet Activating Factor","D010972",60,36,19,42,90]
["Sulfamethoxazole","Sulfamethoxazole","D013420",45,19,22,78,89]
["Cyclophosphamide","Cyclophosphamide","D003520",35,14,106,966,88]
["Tea Tree Oil","Tea Tree Oil","D020947",0,3,0,0,88]
["Acrolein","Acrolein","D000171",27,20,11,30,87]
["Cromolyn Sodium","Cromolyn Sodium","D004205",18,0,25,25,87]
["Cholesterol","Cholesterol","D002784",756,65,85,214,86]
["Diltiazem","Diltiazem","D004110",32,4,18,11,86]
["p-tert-butylphenolformaldehyde resin","p-tert-butylphenolformaldehyde resin","C014273",0,0,0,0,86]
["Dinoprostone","Dinoprostone","D015232",83,142,294,470,85]
["Lanolin","Lanolin","D007809",0,0,1,0,85]
["Minoxidil","Minoxidil","D008914",2,24,0,13,85]
["Chitosan","Chitosan","D048271",86,108,86,96,84]
["9,10-Dimethyl-1,2-benzanthracene","9,10-Dimethyl-1,2-benzanthracene","D015127",16,45,8,54,83]
["Acyclovir","Acyclovir","D000212",11,2,2,42,83]
["Dapsone","Dapsone","D003622",27,22,6,17,83]
["Petrolatum","Petrolatum","D010577",0,0,1,0,82]
["Niacinamide","Niacinamide","D009536",48,47,16,51,81]
["Trimethoprim","Trimethoprim","D014295",54,0,1,17,81]
["Ephedrine","Ephedrine","D004809",7,0,2,0,80]
["Glucose","Glucose","D005947",623,64,48,151,80]
["Nicotine","Nicotine","D009538",152,61,56,110,80]
["Nitroglycerin","Nitroglycerin","D005996",11,4,0,0,80]
["Picryl Chloride","Picryl Chloride","D010853",1,3,11,43,80]
["Niacin","Niacin","D009525",17,8,3,9,79]
["vemurafenib","vemurafenib","C551177",0,21,0,24,79]
["Thalidomide","Thalidomide","D013792",30,8,46,260,77]
["Streptomycin","Streptomycin","D013307",26,1,17,11,76]
["Clindamycin","Clindamycin","D002981",15,4,1,4,75]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C132,B132)","v":"Eugenol"},"Eugenol","D005054",8,18,3,3,75]
["Acetylcholine","Acetylcholine","D000109",184,23,31,60,73]
["diphenylcyclopropenone","diphenylcyclopropenone","C029402",0,4,1,20,73]
["Phenylbutazone","Phenylbutazone","D010653",119,0,16,0,73]
["Propranolol","Propranolol","D011433",221,1,2,54,73]
["Glutaral","Glutaral","D005976",25,0,20,15,72]
["Gold Sodium Thiomalate","Gold Sodium Thiomalate","D006052",23,0,5,52,72]
["Indomethacin","Indomethacin","D007213",86,16,11,107,72]
["Leukotriene B4","Leukotriene B4","D007975",23,26,21,91,72]
["Theophylline","Theophylline","D013806",138,3,9,136,72]
["Triamcinolone","Triamcinolone","D014221",2,0,2,5,72]
["cinnamic aldehyde","cinnamic aldehyde","C012843",8,6,9,6,71]
["EMLA","EMLA","C036626",0,6,0,0,71]
["Tetracycline","Tetracycline","D013752",106,4,16,17,71]
["Toluene 2,4-Diisocyanate","Toluene 2,4-Diisocyanate","D014051",5,0,8,20,71]
["Folic Acid","Folic Acid","D005492",438,25,17,82,70]
["Glycerol","Glycerol","D005990",75,35,13,12,69]
["Rifampin","Rifampin","D012293",101,3,21,52,69]
["Ciprofloxacin","Ciprofloxacin","D002939",50,1,6,27,67]
["Levamisole","Levamisole","D007978",9,0,16,471,67]
["Nevirapine","Nevirapine","D019829",15,0,0,49,67]
["Benzo(a)pyrene","Benzo(a)pyrene","D001564",98,65,11,50,66]
["chlorhexidine gluconate","chlorhexidine gluconate","C010882",4,6,0,0,66]
["Erythromycin","Erythromycin","D004917",76,2,8,39,66]
["Gallic Acid","Gallic Acid","D005707",17,20,3,19,66]
["Penicillin G","Penicillin G","D010400",89,0,38,29,66]
["Povidone","Povidone","D011205",20,10,11,29,66]
["Tea","Tea","D013662",41,35,6,70,66]
["Tetanus Toxoid","Tetanus Toxoid","D013745",8,3,80,197,66]
["Coal Tar","Coal Tar","D003033",3,3,1,4,65]
["Curcumin","Curcumin","D003474",182,100,48,145,65]
["limonene","limonene","C008281",9,3,0,9,65]
["Peruvian balsam","Peruvian balsam","C025080",0,0,0,0,65]
["Turpentine","Turpentine","D014425",5,0,2,0,65]
["Nystatin","Nystatin","D009761",6,6,3,11,63]
["cocamidopropyl betaine","cocamidopropyl betaine","C077055",0,3,0,0,62]
["Mitomycin","Mitomycin","D016685",15,8,27,54,62]
["Pertussis Vaccine","Pertussis Vaccine","D010567",3,0,34,42,62]
["Phenobarbital","Phenobarbital","D010634",159,0,8,5,62]
["Silicon Dioxide","Silicon Dioxide","D012822",133,53,75,93,62]
["SRS-A","SRS-A","D013189",8,0,5,13,62]
["Bufexamac","Bufexamac","D002019",1,1,0,0,61]
["Dipyrone","Dipyrone","D004177",4,0,0,0,61]
["Ethylene Oxide","Ethylene Oxide","D005027",5,7,3,13,61]
["Hydroxyzine","Hydroxyzine","D006919",1,0,2,3,61]
["pimecrolimus","pimecrolimus","C117268",1,13,17,31,61]
["Tetracaine","Tetracaine","D013748",8,4,0,3,61]
["Iohexol","Iohexol","D007472",13,0,1,12,60]
["4,4'-diphenylmethane diisocyanate","4,4'-diphenylmethane diisocyanate","C005969",6,0,1,4,59]
["Etretinate","Etretinate","D005050",4,15,1,24,59]
["gefitinib","gefitinib","C419708",29,15,3,0,59]
["Lactic Acid","Lactic Acid","D019344",68,56,138,145,59]
["Prostaglandins E","Prostaglandins E","D011458",44,0,18,148,59]
["Stainless Steel","Stainless Steel","D013193",12,7,1,0,59]
["Benzocaine","Benzocaine","D001566",4,3,0,0,58]
["Ketoconazole","Ketoconazole","D007654",24,13,0,12,58]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699",1,0,0,6,57]
["Aminophylline","Aminophylline","D000628",9,0,1,13,57]
["Catechin","Catechin","D002392",162,124,32,151,57]
["Chloroquine","Chloroquine","D002738",52,5,68,134,57]
["Doxycycline","Doxycycline","D004318",12,17,3,24,57]
["Ticlopidine","Ticlopidine","D013988",18,0,3,2,57]
["Celecoxib","Celecoxib","D000068579",25,9,18,29,56]
["Disulfiram","Disulfiram","D004221",22,0,0,12,56]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C196,B196)","v":"Fluocinolone Acetonide"},"Fluocinolone Acetonide","D005446",1,8,0,3,56]
["Gold Sodium Thiosulfate","Gold Sodium Thiosulfate","D012971",3,0,1,12,56]
["Propyl Gallate","Propyl Gallate","D011435",5,0,0,3,56]
["Sodium Hypochlorite","Sodium Hypochlorite","D012973",1,13,0,5,56]
["Thioacetazone","Thioacetazone","D013828",1,0,0,0,56]
["Cimetidine","Cimetidine","D002927",48,3,7,80,55]
["Naproxen","Naproxen","D009288",71,1,0,12,55]
["Sodium Chloride","Sodium Chloride","D012965",148,10,18,13,55]
["Amantadine","Amantadine","D000547",16,0,3,10,54]
["Codeine","Codeine","D003061",11,0,1,0,54]
["Neoprene","Neoprene","D009387",2,0,0,0,54]
["Omeprazole","Omeprazole","D009853",25,0,0,1,54]
["p-Methoxy-N-methylphenethylamine","p-Methoxy-N-methylphenethylamine","D003189",4,3,17,0,54]
["Vitamin K 1","Vitamin K 1","D010837",8,0,0,4,54]
["4-Aminobenzoic Acid","4-Aminobenzoic Acid","D010129",8,4,5,1,53]
["sunitinib","sunitinib","C473478",9,4,27,29,53]
["Amiodarone","Amiodarone","D000638",28,3,0,11,52]
["Ranitidine","Ranitidine","D011899",10,0,1,6,52]
["Smallpox Vaccine","Smallpox Vaccine","D012900",2,2,25,108,52]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450",14,0,4,26,51]
["Dimethyl Fumarate","Dimethyl Fumarate","D000069462",1,23,7,28,51]
["sodium metabisulfite","sodium metabisulfite","C005200",0,0,2,0,51]
["squaric acid dibutyl ester","squaric acid dibutyl ester","C020637",0,0,1,7,51]
["Vitamin K","Vitamin K","D014812",73,0,2,3,51]
["Cisplatin","Cisplatin","D002945",324,33,24,114,50]
["Clotrimazole","Clotrimazole","D003022",8,3,0,3,50]
["Menthol","Menthol","D008610",5,5,0,0,50]
["Morphine","Morphine","D009020",150,5,38,261,50]
["Valproic Acid","Valproic Acid","D014635",235,6,9,78,50]
["Arachidonic Acid","Arachidonic Acid","D016718",91,30,16,72,49]
["Measles Vaccine","Measles Vaccine","D008458",3,0,36,80,49]
["Methylcholanthrene","Methylcholanthrene","D008748",69,0,18,25,49]
["Mineral Oil","Mineral Oil","D008899",3,0,6,2,49]
["Nitrofurazone","Nitrofurazone","D009583",4,0,0,0,49]
["Benzyl Alcohol","Benzyl Alcohol","D019905",6,3,0,0,48]
["Coffee","Coffee","D003069",8,3,1,9,48]
["Salicylic Acid","Salicylic Acid","D020156",108,2,0,3,48]
["Terfenadine","Terfenadine","D016593",14,3,1,14,48]
["Adapalene","Adapalene","D000068816",0,3,0,0,47]
["Particulate Matter","Particulate Matter","D052638",6,38,72,36,47]
["tetrazepam","tetrazepam","C005245",0,0,0,0,47]
["Colchicine","Colchicine","D003078",233,5,17,52,46]
["Fluconazole","Fluconazole","D015725",17,4,0,15,46]
["hydroxyethyl methacrylate","hydroxyethyl methacrylate","C005044",8,12,0,1,46]
["Ofloxacin","Ofloxacin","D015242",27,6,0,7,46]
["phenol-formaldehyde resin","phenol-formaldehyde resin","C011529",0,0,0,0,46]
["protoporphyrin IX","protoporphyrin IX","C028025",44,41,6,10,46]
["Sirolimus","Sirolimus","D020123",88,32,193,722,46]
["Spironolactone","Spironolactone","D013148",19,0,1,11,46]
["Zinc Oxide","Zinc Oxide","D015034",27,34,13,15,46]
["Cellulose","Cellulose","D002482",277,21,24,17,45]
["Croton Oil","Croton Oil","D003436",2,1,0,3,45]
["enterotoxin B, staphylococcal","enterotoxin B, staphylococcal","C031818",30,7,90,592,45]
["Polyvinyl Chloride","Polyvinyl Chloride","D011143",7,1,0,6,45]
["Triclosan","Triclosan","D014260",17,3,2,1,45]
["Atracurium","Atracurium","D001279",3,0,0,0,44]
["Diphenhydramine","Diphenhydramine","D004155",15,0,2,0,44]
["Diphtheria-Tetanus-Pertussis Vaccine","Diphtheria-Tetanus-Pertussis Vaccine","D015721",0,0,6,6,44]
["Dopamine","Dopamine","D004298",707,15,33,124,44]
["Quercetin","Quercetin","D011794",94,83,28,33,44]
["resveratrol","resveratrol","C059514",108,93,29,113,44]
["Trichloroethylene","Trichloroethylene","D014241",21,29,0,51,44]
["alpha-Tocopherol","alpha-Tocopherol","D024502",23,25,4,30,43]
["Methenamine","Methenamine","D008709",0,3,0,0,43]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C260,B260)","v":"Methylmethacrylate"},"Methylmethacrylate","D020366",1,0,1,1,43]
["N-isopropyl-N-phenyl-4-phenylenediamine","N-isopropyl-N-phenyl-4-phenylenediamine","C014627",0,0,0,0,43]
["trimellitic anhydride","trimellitic anhydride","C015559",3,0,4,2,43]
["Hydrogel, Polyethylene Glycol Dimethacrylate","Hydrogel, Polyethylene Glycol Dimethacrylate","D020136",14,21,3,8,42]
["Oxazolone","Oxazolone","D010081",4,2,13,38,42]
["Ozone","Ozone","D010126",20,16,26,92,42]
["Vitamin B 12","Vitamin B 12","D014805",476,0,17,16,42]
["Amiloride","Amiloride","D000584",19,4,0,19,41]
["Isoproterenol","Isoproterenol","D007545",46,1,6,44,41]
["Loratadine","Loratadine","D017336",5,3,1,10,41]
["Miconazole","Miconazole","D008825",2,3,0,9,41]
["abietic acid","abietic acid","C023710",1,0,0,0,40]
["Prednisone","Prednisone","D011241",47,0,26,175,40]
["Aminopyrine","Aminopyrine","D000632",16,0,8,0,39]
["Hydroxychloroquine","Hydroxychloroquine","D006886",8,6,4,54,39]
["oxybenzone","oxybenzone","C005290",1,6,0,0,39]
["Starch","Starch","D013213",77,1,4,24,39]
["sulfanilamide","sulfanilamide","C036944",17,0,0,0,39]
["Toluene","Toluene","D014050",35,0,4,34,39]
["tromantadine","tromantadine","C004279",0,0,0,0,39]
["4-Butyrolactone","4-Butyrolactone","D015107",47,11,12,23,38]
["Caffeine","Caffeine","D002110",76,15,3,38,38]
["Castor Oil","Castor Oil","D002368",0,1,1,0,38]
["disperse blue 106","disperse blue 106","C049175",0,0,0,0,38]
["Enoxaparin","Enoxaparin","D017984",7,0,0,3,38]
["epigallocatechin gallate","epigallocatechin gallate","C045651",113,99,29,96,38]
["Fusidic Acid","Fusidic Acid","D005672",22,0,0,11,38]
["Griseofulvin","Griseofulvin","D006118",9,6,1,0,38]
["Itraconazole","Itraconazole","D017964",12,6,0,16,38]
["Lithium Carbonate","Lithium Carbonate","D016651",7,3,3,10,38]
["Procaine","Procaine","D011343",7,0,0,5,38]
["Pyrimethamine","Pyrimethamine","D011739",16,3,2,10,38]
["Amoxicillin-Potassium Clavulanate Combination","Amoxicillin-Potassium Clavulanate Combination","D019980",1,0,0,5,37]
["etofenamate","etofenamate","C015207",0,0,0,0,37]
["Flufenamic Acid","Flufenamic Acid","D005439",8,0,0,0,37]
["Prostaglandin D2","Prostaglandin D2","D015230",52,24,34,54,37]
["Albuterol","Albuterol","D000420",15,3,11,30,36]
["Carboxymethylcellulose Sodium","Carboxymethylcellulose Sodium","D002266",7,6,9,24,36]
["Fentanyl","Fentanyl","D005283",48,0,2,20,36]
["glycolic acid","glycolic acid","C031149",2,28,0,0,36]
["Nifedipine","Nifedipine","D009543",42,13,0,11,36]
["Quinine","Quinine","D011803",40,0,7,5,36]
["Sorbic Acid","Sorbic Acid","D013011",1,0,0,3,36]
["Timolol","Timolol","D013999",4,0,0,3,36]
["tioconazole","tioconazole","C020527",0,0,0,0,36]
["Acetone","Acetone","D000096",25,7,5,3,35]
["Bortezomib","Bortezomib","D000069286",27,6,47,80,35]
["sorbitan sesquioleate","sorbitan sesquioleate","C058854",0,0,0,0,35]
["Alprostadil","Alprostadil","D000527",16,12,7,63,34]
["Betamethasone Valerate","Betamethasone Valerate","D001624",0,0,0,0,34]
["bisphenol A","bisphenol A","C006780",58,0,17,32,34]
["diazolidinylurea","diazolidinylurea","C044982",0,0,0,0,34]
["Edetic Acid","Edetic Acid","D004492",88,7,14,12,34]
["Fluoxetine","Fluoxetine","D005473",51,0,6,62,34]
["Furosemide","Furosemide","D005665",100,0,0,9,34]
["geraniol","geraniol","C007836",1,6,0,1,34]
["Mercuric Chloride","Mercuric Chloride","D008627",13,19,3,180,34]
["Practolol","Practolol","D011217",5,0,0,5,34]
["Doxepin","Doxepin","D004316",9,0,0,3,33]
["hydroxyisohexyl 3-cyclohexene carboxaldehyde","hydroxyisohexyl 3-cyclohexene carboxaldehyde","C092244",0,0,0,0,33]
["Mometasone Furoate","Mometasone Furoate","D000068656",7,6,0,0,33]
["Olive Oil","Olive Oil","D000069463",4,3,1,11,33]
["omega-Chloroacetophenone","omega-Chloroacetophenone","D002721",1,0,0,0,33]
["Tamoxifen","Tamoxifen","D013629",136,14,12,30,33]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C324,B324)","v":"DEET"},"DEET","D003671",3,3,0,2,32]
["leflunomide","leflunomide","C045463",3,3,24,114,32]
["liposomal doxorubicin","liposomal doxorubicin","C506643",2,3,1,3,32]
["mezerein","mezerein","C011309",1,12,3,11,32]
["Pentoxifylline","Pentoxifylline","D010431",2,11,6,103,32]
["Urocanic Acid","Urocanic Acid","D014560",6,30,12,23,32]
["4,4'-diaminodiphenylmethane","4,4'-diaminodiphenylmethane","C009505",0,0,0,0,31]
["Bupivacaine","Bupivacaine","D002045",58,0,0,10,31]
["chloroacetamide","chloroacetamide","C013874",0,0,0,0,31]
["fondaparinux","fondaparinux","C438268",10,0,0,0,31]
["Ivermectin","Ivermectin","D007559",22,0,1,13,31]
["Oleic Acid","Oleic Acid","D019301",66,11,1,18,31]
["Quinidine","Quinidine","D011802",123,0,7,1,31]
["Silver Sulfadiazine","Silver Sulfadiazine","D012837",0,14,0,0,31]
["tazarotene","tazarotene","C086827",1,18,0,0,31]
["Trichloroacetic Acid","Trichloroacetic Acid","D014238",15,6,1,3,31]
["urushiol","urushiol","C003747",2,0,2,8,31]
["Amifostine","Amifostine","D004999",5,4,0,16,30]
["Camphor","Camphor","D002164",14,10,0,3,30]
["chlorocresol","chlorocresol","C006984",1,0,0,0,30]
["Dibucaine","Dibucaine","D003992",5,0,0,0,30]
["Ethambutol","Ethambutol","D004977",4,0,0,1,30]
["Ketotifen","Ketotifen","D007665",0,0,0,20,30]
["Merbromin","Merbromin","D008622",2,0,0,2,30]
["o-Chlorobenzylidenemalonitrile","o-Chlorobenzylidenemalonitrile","D009763",0,0,0,0,30]
["2-n-octyl-4-isothiazolin-3-one","2-n-octyl-4-isothiazolin-3-one","C035331",0,0,0,0,29]
["3-iodo-2-propynylbutylcarbamate","3-iodo-2-propynylbutylcarbamate","C106572",0,0,0,0,29]
["Amphotericin B","Amphotericin B","D000666",29,6,4,64,29]
["Atropine","Atropine","D001285",26,0,3,6,29]
["Aurothioglucose","Aurothioglucose","D006051",7,0,3,8,29]
["coumarin","coumarin","C030123",41,9,1,4,29]
["Ditiocarb","Ditiocarb","D004050",14,0,0,68,29]
["hydroquinone","hydroquinone","C031927",17,6,0,20,29]
["linalool","linalool","C018584",1,0,0,0,29]
["Methacholine Chloride","Methacholine Chloride","D016210",0,0,0,2,29]
["Penicillin V","Penicillin V","D010404",14,0,1,1,29]
["phenoxyethanol","phenoxyethanol","C005398",0,0,0,0,29]
["Smoke","Smoke","D012906",12,27,39,71,29]
["triethanolamine","triethanolamine","C009546",1,0,0,0,29]
["Acitretin","Acitretin","D017255",5,25,0,4,28]
["aluminum chloride","aluminum chloride","C010845",6,0,0,12,28]
["Benzoic Acid","Benzoic Acid","D019817",12,0,2,1,28]
["Diphtheria Toxoid","Diphtheria Toxoid","D004168",9,0,48,29,28]
["Disperse Blue 124","Disperse Blue 124","C069319",0,0,0,0,28]
["etoricoxib","etoricoxib","C422649",1,0,0,2,28]
["fepradinol","fepradinol","C078462",0,0,0,0,28]
["iodixanol","iodixanol","C044834",2,0,3,3,28]
["Levobunolol","Levobunolol","D002040",0,0,0,0,28]
["Pyridoxine","Pyridoxine","D011736",22,0,7,12,28]
["quaternium-15","quaternium-15","C018375",0,0,0,0,28]
["2,2-bis(4-glycidyloxyphenyl)propane","2,2-bis(4-glycidyloxyphenyl)propane","C019273",1,0,0,1,27]
["3-dimethylaminopropylamine","3-dimethylaminopropylamine","C012928",0,0,0,0,27]
["Antipyrine","Antipyrine","D000983",43,0,1,4,27]
["Brimonidine Tartrate","Brimonidine Tartrate","D000068438",1,0,0,3,27]
["captax","captax","C005563",0,0,0,2,27]
["citral","citral","C007076",2,0,0,0,27]
["dibenzothiazyl disulfide","dibenzothiazyl disulfide","C028000",0,0,3,0,27]
["Flurbiprofen","Flurbiprofen","D005480",42,4,3,6,27]
["Kerosene","Kerosene","D007648",0,6,0,6,27]
["nimesulide","nimesulide","C012655",8,3,0,0,27]
["oleoresins","oleoresins","C018620",0,0,0,2,27]
["Tartrazine","Tartrazine","D013645",3,0,0,3,27]
["Vinblastine","Vinblastine","D014747",76,0,6,25,27]
["Benzene","Benzene","D001554",43,0,7,83,26]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C388,B388)","v":"Bisphenol A-Glycidyl Methacrylate"},"Bisphenol A-Glycidyl Methacrylate","D017438",0,6,0,0,26]
["Ceftriaxone","Ceftriaxone","D002443",72,0,4,15,26]
["Heparitin Sulfate","Heparitin Sulfate","D006497",426,21,38,62,26]
["lenalidomide","lenalidomide","C467567",14,0,31,109,26]
["Maneb","Maneb","D008344",3,3,0,2,26]
["octyl 2-cyanoacrylate","octyl 2-cyanoacrylate","C100832",0,0,0,0,26]
["primin","primin","C014773",0,0,0,0,26]
["Sphingosine","Sphingosine","D013110",106,95,90,372,26]
["2-((2'-quinolinyl)-1,3-indandione)","2-((2'-quinolinyl)-1,3-indandione)","C027012",0,0,0,0,25]
["amcinonide","amcinonide","C012716",0,0,0,0,25]
["Azithromycin","Azithromycin","D017963",7,1,21,25,25]
["Aztreonam","Aztreonam","D001398",6,0,0,2,25]
["beta Carotene","beta Carotene","D019207",27,29,5,55,25]
["Buprenorphine","Buprenorphine","D002047",20,0,0,12,25]
["Ceftazidime","Ceftazidime","D002442",18,0,0,3,25]
["Cephalexin","Cephalexin","D002506",13,0,0,0,25]
["Chlorpheniramine","Chlorpheniramine","D002744",6,3,1,0,25]
["dabrafenib","dabrafenib","C561627",1,1,0,18,25]
["Diethylhexyl Phthalate","Diethylhexyl Phthalate","D004051",14,4,7,4,25]
["diethylthiourea","diethylthiourea","C035318",0,0,0,0,25]
["Dihematoporphyrin Ether","Dihematoporphyrin Ether","D017323",7,9,3,4,25]
["Epoprostenol","Epoprostenol","D011464",30,4,26,25,25]
["Hexachlorophene","Hexachlorophene","D006582",3,0,0,0,25]
["Hydralazine","Hydralazine","D006830",13,0,4,15,25]
["imidazolidinyl urea","imidazolidinyl urea","C006048",1,0,0,0,25]
["Linoleic Acid","Linoleic Acid","D019787",22,12,0,24,25]
["Mesalamine","Mesalamine","D019804",6,0,4,11,25]
["Naltrexone","Naltrexone","D009271",30,0,11,43,25]
["Phenindione","Phenindione","D010630",0,0,0,1,25]
["potassium persulfate","potassium persulfate","C009007",0,0,0,1,25]
["prednicarbate","prednicarbate","C035287",0,11,0,0,25]
["pyrazolone","pyrazolone","C038362",2,0,0,1,25]
["retinol palmitate","retinol palmitate","C014794",3,2,3,3,25]
["tall oil","tall oil","C482568",0,0,0,0,25]
["Voriconazole","Voriconazole","D065819",16,6,3,4,25]
["2,5-diaminotoluene","2,5-diaminotoluene","C007303",0,0,0,6,24]
["2-Propanol","2-Propanol","D019840",5,0,0,3,24]
["Arsphenamine","Arsphenamine","D001153",0,0,2,0,24]
["butylphen","butylphen","C006862",1,9,1,3,24]
["Carbon Dioxide","Carbon Dioxide","D002245",81,7,2,2,24]
["Clavulanic Acid","Clavulanic Acid","D019818",6,0,0,1,24]
["clopidogrel","clopidogrel","C055162",13,0,3,1,24]
["Dermatan Sulfate","Dermatan Sulfate","D003871",56,14,1,4,24]
["Dimercaprol","Dimercaprol","D004112",3,0,3,3,24]
["diphenylthiourea","diphenylthiourea","C032788",1,0,0,0,24]
["enterotoxin F, Staphylococcal","enterotoxin F, Staphylococcal","C030107",25,1,44,271,24]
["glyceryl monothioglycolate","glyceryl monothioglycolate","C033769",0,0,0,0,24]
["Guanine","Guanine","D006147",152,10,15,95,24]
["isoeugenol","isoeugenol","C036643",0,6,0,3,24]
["Levofloxacin","Levofloxacin","D064704",12,3,0,1,24]
["Measles-Mumps-Rubella Vaccine","Measles-Mumps-Rubella Vaccine","D022542",0,0,1,16,24]
["Methylcellulose","Methylcellulose","D008747",9,6,3,9,24]
["pyrithione zinc","pyrithione zinc","C010423",1,6,0,0,24]
["Succinylcholine","Succinylcholine","D013390",3,0,1,0,24]
["Sulfadiazine","Sulfadiazine","D013411",26,0,1,4,24]
["4-isopropyldibenzoylmethane","4-isopropyldibenzoylmethane","C049936",0,0,0,0,23]
["acrylic acid","acrylic acid","C036658",7,3,0,0,23]
["alantolactone","alantolactone","C004363",4,3,0,0,23]
["Ammonium Sulfate","Ammonium Sulfate","D000645",12,0,4,1,23]
["Cyanamide","Cyanamide","D003484",3,0,0,1,23]
["Dacarbazine","Dacarbazine","D003606",13,3,19,64,23]
["Dicyclohexylcarbodiimide","Dicyclohexylcarbodiimide","D004024",50,0,1,0,23]
["Fluticasone","Fluticasone","D000068298",6,0,15,61,23]
["Hydrochlorothiazide","Hydrochlorothiazide","D006852",7,0,1,1,23]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C452,B452)","v":"icodextrin"},"icodextrin","C105834",0,0,0,0,23]
["Industrial Waste","Industrial Waste","D007220",2,4,3,9,23]
["Leukotriene E4","Leukotriene E4","D017999",1,0,0,1,23]
["methylparaben","methylparaben","C015358",2,9,0,0,23]
["Methylphenidate","Methylphenidate","D008774",26,0,1,0,23]
["montelukast","montelukast","C093875",1,0,6,15,23]
["Ouabain","Ouabain","D010042",223,0,9,22,23]
["oxaliplatin","oxaliplatin","C030110",25,0,10,9,23]
["Propylthiouracil","Propylthiouracil","D011441",25,3,1,7,23]
["resorcinol","resorcinol","C031389",3,0,0,0,23]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262",4,0,3,3,22]
["1-Propanol","1-Propanol","D000433",6,0,1,1,22]
["Auranofin","Auranofin","D001310",7,0,9,32,22]
["Benzydamine","Benzydamine","D001591",1,0,0,0,22]
["Clioquinol","Clioquinol","D007464",11,0,0,1,22]
["Cyproheptadine","Cyproheptadine","D003533",2,0,2,0,22]
["Diazepam","Diazepam","D003975",177,0,0,29,22]
["Dibutyl Phthalate","Dibutyl Phthalate","D003993",6,0,12,7,22]
["Genistein","Genistein","D019833",55,33,3,59,22]
["Iopamidol","Iopamidol","D007479",3,1,0,12,22]
["methylprednisolone aceponate","methylprednisolone aceponate","C078007",2,0,0,0,22]
["Phosphonoacetic Acid","Phosphonoacetic Acid","D010746",11,0,0,8,22]
["Polymethyl Methacrylate","Polymethyl Methacrylate","D019904",15,0,4,1,22]
["Potassium Iodide","Potassium Iodide","D011193",10,0,1,1,22]
["Restylane","Restylane","C445361",0,0,0,1,22]
["rofecoxib","rofecoxib","C116926",5,0,0,3,22]
["Rutin","Rutin","D012431",19,0,0,16,22]
["Aminosalicylic Acid","Aminosalicylic Acid","D010131",6,0,1,4,21]
["Amitriptyline","Amitriptyline","D000639",22,3,0,3,21]
["Bromhexine","Bromhexine","D001964",0,0,0,0,21]
["bronopol","bronopol","C006827",0,0,3,0,21]
["Chitin","Chitin","D002686",157,27,4,17,21]
["Chlorambucil","Chlorambucil","D002699",29,0,4,31,21]
["Chlorogenic Acid","Chlorogenic Acid","D002726",18,10,4,12,21]
["Cholecalciferol","Cholecalciferol","D002762",100,103,82,86,21]
["Cocaine","Cocaine","D003042",226,2,19,113,21]
["crotamiton","crotamiton","C005553",0,0,0,0,21]
["Epichlorohydrin","Epichlorohydrin","D004811",1,0,0,3,21]
["Fluorescein-5-isothiocyanate","Fluorescein-5-isothiocyanate","D016650",49,8,42,40,21]
["Leukotriene C4","Leukotriene C4","D017997",4,1,9,9,21]
["Lindane","Lindane","D001556",8,0,2,4,21]
["Mepivacaine","Mepivacaine","D008619",2,0,0,0,21]
["Parathion","Parathion","D010278",18,0,0,9,21]
["phosphorus sesquisulfide","phosphorus sesquisulfide","C033768",0,0,0,0,21]
["Scopolamine Hydrobromide","Scopolamine Hydrobromide","D012601",4,0,0,1,21]
["Suramin","Suramin","D013498",69,7,2,19,21]
["Thiopental","Thiopental","D013874",76,0,1,22,21]
["Tobramycin","Tobramycin","D014031",14,0,0,3,21]
["2-chloroethyl ethyl sulfide","2-chloroethyl ethyl sulfide","C031278",3,36,0,3,20]
["alpha-methylene gamma-butyrolactone","alpha-methylene gamma-butyrolactone","C014096",1,0,0,0,20]
["amlexanox","amlexanox","C045742",9,0,0,0,20]
["Apomorphine","Apomorphine","D001058",23,0,0,5,20]
["Beclomethasone","Beclomethasone","D001507",2,0,0,32,20]
["Benzoin Gum","Benzoin Gum","C457659",0,0,0,0,20]
["Bupropion","Bupropion","D016642",10,0,0,1,20]
["Caprolactam","Caprolactam","D002209",0,0,0,0,20]
["CD3 Complex","CD3 Complex","D017252",94,1,165,2476,20]
["Dasatinib","Dasatinib","D000069439",20,0,7,60,20]
["Ethyl Chloride","Ethyl Chloride","D005018",0,0,0,0,20]
["oxcarbazepine","oxcarbazepine","C036006",7,0,0,1,20]
["polidocanol","polidocanol","C008976",5,0,0,0,20]
["Polyvinyl Alcohol","Polyvinyl Alcohol","D011142",12,11,2,4,20]
["Propofol","Propofol","D015742",56,0,10,26,20]
["Pyrazinamide","Pyrazinamide","D011718",8,0,3,5,20]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C516,B516)","v":"Sertraline"},"Sertraline","D020280",10,0,0,3,20]
["Silymarin","Silymarin","D012838",19,26,3,57,20]
["Sodium Hydroxide","Sodium Hydroxide","D012972",4,0,0,0,20]
["sulfan blue","sulfan blue","C008769",0,0,1,0,20]
["3-ingenyl angelate","3-ingenyl angelate","C486592",1,17,1,14,19]
["avobenzone","avobenzone","C049935",0,0,0,0,19]
["Barium Sulfate","Barium Sulfate","D001466",0,0,1,0,19]
["bisphenol A epoxy resin diacrylate ester","bisphenol A epoxy resin diacrylate ester","C029420",0,0,0,0,19]
["calcium heparin","calcium heparin","C006871",0,0,0,0,19]
["Clarithromycin","Clarithromycin","D017291",9,3,7,14,19]
["diallyl disulfide","diallyl disulfide","C028009",4,3,0,4,19]
["dorzolamide","dorzolamide","C062765",4,0,0,0,19]
["Gadolinium DTPA","Gadolinium DTPA","D019786",9,3,1,0,19]
["Mafenide","Mafenide","D008272",0,9,0,0,19]
["Mesna","Mesna","D015080",4,0,0,3,19]
["Metformin","Metformin","D008687",36,4,1,32,19]
["methylene bis(4-cyclohexylisocyanate)","methylene bis(4-cyclohexylisocyanate)","C013606",1,0,2,3,19]
["Oxyphenbutazone","Oxyphenbutazone","D010113",17,0,6,3,19]
["Paraquat","Paraquat","D010269",24,9,2,5,19]
["Piperacillin","Piperacillin","D010878",8,0,6,6,19]
["Polyglycolic Acid","Polyglycolic Acid","D011100",25,29,117,101,19]
["T-2 Toxin","T-2 Toxin","D013605",9,6,6,43,19]
["tetrachloroisophthalonitrile","tetrachloroisophthalonitrile","C005806",0,0,0,0,19]
["Tolnaftate","Tolnaftate","D014047",0,0,0,0,19]
["Tranexamic Acid","Tranexamic Acid","D014148",8,7,0,0,19]
["1,3-dibutyl-2-thiourea","1,3-dibutyl-2-thiourea","C034546",0,0,0,0,18]
["4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide","4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide","C498826",5,0,2,17,18]
["Butylated Hydroxytoluene","Butylated Hydroxytoluene","D002084",9,4,0,4,18]
["carvone","carvone","C006923",0,0,0,0,18]
["Cefaclor","Cefaclor","D002433",1,0,0,0,18]
["Cefotiam","Cefotiam","D015310",6,0,0,0,18]
["ciclopirox","ciclopirox","C011585",0,0,0,0,18]
["danaparoid","danaparoid","C035838",3,0,1,0,18]
["deferasirox","deferasirox","C415250",6,0,0,0,18]
["Durapatite","Durapatite","D017886",89,4,5,5,18]
["enterotoxin A, Staphylococcal","enterotoxin A, Staphylococcal","C026066",16,1,31,297,18]
["Ficusin","Ficusin","D005363",10,13,1,17,18]
["Freund's Adjuvant","Freund's Adjuvant","D005620",5,0,140,85,18]
["levocetirizine","levocetirizine","C472067",2,3,0,0,18]
["meropenem","meropenem","C059500",13,1,0,3,18]
["musk ambrette (artificial)","musk ambrette (artificial)","C020422",0,0,0,0,18]
["Pilocarpine","Pilocarpine","D010862",5,0,1,6,18]
["Promethazine","Promethazine","D011398",13,0,1,6,18]
["Pyrrolnitrin","Pyrrolnitrin","D011764",0,0,0,0,18]
["royal jelly","royal jelly","C058787",0,3,3,10,18]
["Sulfadoxine","Sulfadoxine","D013413",1,0,0,2,18]
["teroxirone","teroxirone","C028786",0,0,0,0,18]
["Thymol","Thymol","D013943",6,0,6,3,18]
["Ubiquinone","Ubiquinone","D014451",91,25,0,21,18]
["vinorelbine","vinorelbine","C030852",4,0,1,1,18]
["VX","VX","C009680",7,0,1,0,18]
["2-Naphthylamine","2-Naphthylamine","D015081",28,0,0,7,17]
["Acenocoumarol","Acenocoumarol","D000074",13,0,0,0,17]
["Aluminum Oxide","Aluminum Oxide","D000537",11,6,1,2,17]
["aniline","aniline","C023650",9,0,1,3,17]
["azelaic acid","azelaic acid","C010038",1,12,0,3,17]
["Calcimycin","Calcimycin","D000001",6,4,31,120,17]
["Cloxacillin","Cloxacillin","D003023",30,0,0,0,17]
["ethyl sebacate","ethyl sebacate","C029410",0,0,0,0,17]
["fexofenadine","fexofenadine","C093230",2,3,1,10,17]
["gamma-Linolenic Acid","gamma-Linolenic Acid","D017965",3,0,0,18,17]
["Gentian Violet","Gentian Violet","D005840",5,1,0,0,17]
["Glucosamine","Glucosamine","D005944",104,8,19,36,17]
["iopromide","iopromide","C038192",2,0,0,0,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C580,B580)","v":"methyl salicylate"},"methyl salicylate","C033069",1,0,0,0,17]
["methylene bis-benzotriazolyl tetramethylphenol","methylene bis-benzotriazolyl tetramethylphenol","C500403",0,0,0,0,17]
["Misonidazole","Misonidazole","D008920",9,0,1,0,17]
["Oxytetracycline","Oxytetracycline","D010118",30,0,1,4,17]
["Paraffin","Paraffin","D010232",1,1,0,5,17]
["Phenol","Phenol","D019800",27,3,1,0,17]
["piperazine","piperazine","C034930",31,0,0,0,17]
["p-tert-butyl catechol","p-tert-butyl catechol","C015047",0,0,0,0,17]
["Rivastigmine","Rivastigmine","D000068836",2,0,0,1,17]
["Simvastatin","Simvastatin","D019821",32,4,24,63,17]
["Thioctic Acid","Thioctic Acid","D008063",39,12,3,45,17]
["Verapamil","Verapamil","D014700",76,0,6,43,17]
["2-thiosalicylic acid","2-thiosalicylic acid","C026196",0,0,0,0,16]
["Ammonia","Ammonia","D000641",36,1,3,7,16]
["bacampicillin","bacampicillin","C011674",0,0,0,0,16]
["black rubber","black rubber","C053264",0,0,0,0,16]
["Blood Glucose","Blood Glucose","D001786",67,0,10,33,16]
["Calcium Hydroxide","Calcium Hydroxide","D002126",1,0,0,0,16]
["cetyl alcohol","cetyl alcohol","C005031",1,0,0,0,16]
["Chewing Gum","Chewing Gum","D002638",0,0,0,0,16]
["Cysteamine","Cysteamine","D003543",11,10,2,11,16]
["ethyl 2-cyanoacrylate","ethyl 2-cyanoacrylate","C029054",0,0,0,0,16]
["fanasil, pyrimethamine drug combination","fanasil, pyrimethamine drug combination","C001205",1,0,0,2,16]
["Flutamide","Flutamide","D005485",10,1,0,7,16]
["JP8 aviation fuel","JP8 aviation fuel","C098607",0,20,0,9,16]
["kojic acid","kojic acid","C011890",1,18,0,0,16]
["laurocapram","laurocapram","C035229",0,0,0,0,16]
["lavender oil","lavender oil","C045718",0,0,0,0,16]
["lipoteichoic acid","lipoteichoic acid","C009900",31,10,33,44,16]
["olanzapine","olanzapine","C076029",20,0,0,1,16]
["Olopatadine Hydrochloride","Olopatadine Hydrochloride","D000069605",3,6,2,15,16]
["Ondansetron","Ondansetron","D017294",3,3,0,0,16]
["polylactic acid-polyglycolic acid copolymer","polylactic acid-polyglycolic acid copolymer","C043435",25,31,126,107,16]
["Propantheline","Propantheline","D011413",0,0,0,0,16]
["ricinoleic acid","ricinoleic acid","C030521",0,0,0,0,16]
["shellac","shellac","C003934",0,0,0,0,16]
["sodium arsenite","sodium arsenite","C017947",8,83,3,49,16]
["tenoxicam","tenoxicam","C032801",12,0,0,0,16]
["Terbutaline","Terbutaline","D013726",11,0,0,3,16]
["Tinidazole","Tinidazole","D014011",1,0,0,1,16]
["Tramadol","Tramadol","D014147",8,0,0,12,16]
["Trichophytin","Trichophytin","D014248",0,4,5,8,16]
["Zineb","Zineb","D015038",2,3,0,4,16]
["1,3-butylene glycol","1,3-butylene glycol","C028491",0,0,0,0,15]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377",6,18,0,7,15]
["2-Hydroxypropyl-beta-cyclodextrin","2-Hydroxypropyl-beta-cyclodextrin","D000073738",19,3,0,0,15]
["Albendazole","Albendazole","D015766",4,0,1,15,15]
["alginic acid","alginic acid","C008970",31,18,10,17,15]
["Atenolol","Atenolol","D001262",5,0,0,4,15]
["betamethasone-17,21-dipropionate","betamethasone-17,21-dipropionate","C011175",0,15,0,4,15]
["Cantharidin","Cantharidin","D002193",9,1,7,1,15]
["cetrimonium","cetrimonium","C004322",10,3,0,1,15]
["Chlorobutanol","Chlorobutanol","D002724",0,0,0,0,15]
["clobetasone butyrate","clobetasone butyrate","C010893",0,0,0,0,15]
["coconut diethanolamide","coconut diethanolamide","C038019",0,0,0,0,15]
["DDT","DDT","D003634",37,0,0,7,15]
["dehydroabietic acid","dehydroabietic acid","C013913",3,0,0,0,15]
["Desonide","Desonide","D003898",0,0,0,0,15]
["Epirubicin","Epirubicin","D015251",9,3,1,4,15]
["Etoposide","Etoposide","D005047",75,0,7,48,15]
["Framycetin","Framycetin","D005601",11,0,0,0,15]
["Fructose","Fructose","D005632",38,4,1,4,15]
["Glycyrrhetinic Acid","Glycyrrhetinic Acid","D006034",22,7,8,32,15]
["Hematoporphyrin Derivative","Hematoporphyrin Derivative","D017324",5,0,0,2,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C644,B644)","v":"Hydrofluoric Acid"},"Hydrofluoric Acid","D006858",0,0,0,0,15]
["Hypochlorous Acid","Hypochlorous Acid","D006997",26,7,6,7,15]
["latoconazole","latoconazole","C072774",0,3,0,0,15]
["laurel oil","laurel oil","C045167",0,0,0,0,15]
["Levonorgestrel","Levonorgestrel","D016912",9,0,3,10,15]
["lycopene","lycopene","C015329",7,8,1,7,15]
["Malathion","Malathion","D008294",9,1,0,15,15]
["meloxicam","meloxicam","C065757",8,0,0,17,15]
["Methimazole","Methimazole","D008713",9,0,10,39,15]
["Nicorandil","Nicorandil","D020108",1,0,0,0,15]
["Nitrogen Dioxide","Nitrogen Dioxide","D009585",3,3,1,10,15]
["Norfloxacin","Norfloxacin","D009643",20,0,4,3,15]
["octocrylene","octocrylene","C088673",0,0,0,0,15]
["Paroxetine","Paroxetine","D017374",20,0,0,0,15]
["Penicillanic Acid","Penicillanic Acid","D010397",11,0,1,0,15]
["peppermint oil","peppermint oil","C015424",0,0,0,0,15]
["Perylene","Perylene","D010569",24,21,3,11,15]
["phthalic acid","phthalic acid","C032279",9,0,3,5,15]
["plicatic acid","plicatic acid","C008938",0,0,0,1,15]
["Poloxamer","Poloxamer","D020442",8,4,6,6,15]
["pramoxine","pramoxine","C005548",1,0,0,0,15]
["Pravastatin","Pravastatin","D017035",10,0,3,11,15]
["Sesame Oil","Sesame Oil","D012715",0,0,0,2,15]
["Singlet Oxygen","Singlet Oxygen","D026082",14,19,0,0,15]
["Sodium Fluoride","Sodium Fluoride","D012969",9,9,1,16,15]
["stearyl alcohol","stearyl alcohol","C009316",0,0,0,0,15]
["Tegafur","Tegafur","D005641",2,0,4,5,15]
["tert-butylcatechol","tert-butylcatechol","C038096",0,0,0,0,15]
["valdecoxib","valdecoxib","C406224",4,0,0,0,15]
["2-hydroxyethyl-dimethylsulfoxonium","2-hydroxyethyl-dimethylsulfoxonium","C033899",0,0,0,0,14]
["5-methoxypsoralen","5-methoxypsoralen","C022909",4,3,0,3,14]
["Alendronate","Alendronate","D019386",6,0,0,15,14]
["Ambroxol","Ambroxol","D000551",1,0,3,0,14]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059",8,5,41,107,14]
["aziridine","aziridine","C033132",0,0,0,2,14]
["benazol P","benazol P","C033674",0,0,0,0,14]
["Camptothecin","Camptothecin","D002166",69,9,4,17,14]
["Carboplatin","Carboplatin","D016190",38,0,6,9,14]
["chloroxylenol","chloroxylenol","C007027",0,0,0,0,14]
["Chlorphenesin","Chlorphenesin","D002743",0,0,0,3,14]
["coenzyme Q10","coenzyme Q10","C024989",17,19,0,3,14]
["Desipramine","Desipramine","D003891",28,3,1,15,14]
["Diatrizoate Meglumine","Diatrizoate Meglumine","D003974",2,0,0,0,14]
["didecyldimethylammonium","didecyldimethylammonium","C027118",0,0,0,5,14]
["Diethylstilbestrol","Diethylstilbestrol","D004054",68,0,5,63,14]
["Dihydroxyacetone","Dihydroxyacetone","D004098",2,3,0,0,14]
["Dimenhydrinate","Dimenhydrinate","D004111",0,0,1,0,14]
["dimethylglyoxime","dimethylglyoxime","C013501",0,0,0,0,14]
["Dinoprost","Dinoprost","D015237",25,5,0,10,14]
["Dispersion Yellow 3","Dispersion Yellow 3","C024957",0,0,0,0,14]
["Eicosapentaenoic Acid","Eicosapentaenoic Acid","D015118",21,18,18,79,14]
["evening primrose oil","evening primrose oil","C028498",0,0,0,2,14]
["Farnesol","Farnesol","D005204",9,3,4,16,14]
["galactosyl-(1-3)galactose","galactosyl-(1-3)galactose","C055075",5,0,11,16,14]
["hydroxycitronellal","hydroxycitronellal","C020755",0,0,0,2,14]
["Imipenem","Imipenem","D015378",13,0,0,7,14]
["isophorone diamine","isophorone diamine","C052964",0,0,0,0,14]
["methylprednisolone acetate","methylprednisolone acetate","C000873",0,0,0,3,14]
["Nadroparin","Nadroparin","D017762",1,0,0,0,14]
["Nifuratel","Nifuratel","D009545",0,0,0,0,14]
["nylon 6","nylon 6","C009916",0,0,0,0,14]
["octylmethoxycinnamate","octylmethoxycinnamate","C118580",0,3,0,1,14]
["Penicillin G Benzathine","Penicillin G Benzathine","D010401",0,0,2,0,14]
["Permethrin","Permethrin","D026023",6,3,0,6,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C708,B708)","v":"Phenoxybenzamine"},"Phenoxybenzamine","D010643",7,0,0,0,14]
["phenyl salicylate","phenyl salicylate","C026041",0,0,0,0,14]
["Podophyllotoxin","Podophyllotoxin","D011034",41,3,0,2,14]
["Proguanil","Proguanil","D002727",3,0,1,0,14]
["Prostaglandins F","Prostaglandins F","D011460",14,0,5,5,14]
["Quinacrine","Quinacrine","D011796",29,0,5,15,14]
["quinoline yellow","quinoline yellow","C019303",1,0,0,0,14]
["sevoflurane","sevoflurane","C009250",18,0,1,16,14]
["Steel","Steel","D013232",0,0,0,0,14]
["Sulindac","Sulindac","D013467",20,1,0,4,14]
["thiocolchicoside","thiocolchicoside","C004280",2,0,0,0,14]
["tributyltin","tributyltin","C011559",8,10,3,52,14]
["zinc chloride","zinc chloride","C016837",15,0,0,21,14]
["2-ethylhexyl salicylate","2-ethylhexyl salicylate","C103422",0,3,0,0,13]
["Acetic Acid","Acetic Acid","D019342",14,1,1,5,13]
["Alfaxalone Alfadolone Mixture","Alfaxalone Alfadolone Mixture","D000530",6,0,0,0,13]
["Allylamine","Allylamine","D000499",3,1,0,1,13]
["Aminopterin","Aminopterin","D000630",7,0,3,7,13]
["Amlodipine","Amlodipine","D017311",12,0,0,1,13]
["ammonium peroxydisulfate","ammonium peroxydisulfate","C031276",0,0,0,1,13]
["Asbestos","Asbestos","D001194",16,0,3,39,13]
["asiaticoside","asiaticoside","C004446",1,8,0,0,13]
["atranorin","atranorin","C026304",1,0,0,0,13]
["Calcium Chloride","Calcium Chloride","D002122",27,0,0,4,13]
["carbopol 940","carbopol 940","C006903",20,0,4,11,13]
["cetostearyl alcohol","cetostearyl alcohol","C010405",0,0,0,0,13]
["Chloral Hydrate","Chloral Hydrate","D002697",11,3,0,11,13]
["Clemastine","Clemastine","D002974",0,0,0,0,13]
["Clozapine","Clozapine","D003024",36,0,1,10,13]
["Coal","Coal","D003031",0,0,0,15,13]
["Copper Sulfate","Copper Sulfate","D019327",4,3,0,3,13]
["Dalteparin","Dalteparin","D017985",7,0,1,0,13]
["ebastine","ebastine","C058249",3,0,0,0,13]
["efavirenz","efavirenz","C098320",18,6,0,38,13]
["enzacamene","enzacamene","C038939",0,0,0,0,13]
["fenbufen","fenbufen","C010725",5,3,0,0,13]
["Fluorescein","Fluorescein","D019793",25,3,13,7,13]
["gadodiamide","gadodiamide","C064925",1,3,0,0,13]
["glyceryl methacrylate","glyceryl methacrylate","C069750",0,0,0,0,13]
["Iloprost","Iloprost","D016285",3,0,12,12,13]
["Impregum","Impregum","C022821",0,0,0,0,13]
["iomeprol","iomeprol","C057937",2,0,0,3,13]
["Ioxaglic Acid","Ioxaglic Acid","D007485",5,0,0,0,13]
["Labetalol","Labetalol","D007741",3,3,0,3,13]
["Loctite","Loctite","C038690",0,0,0,0,13]
["Lovastatin","Lovastatin","D008148",17,14,12,56,13]
["Mercaptopurine","Mercaptopurine","D015122",21,0,36,72,13]
["naftifine","naftifine","C029178",1,0,0,0,13]
["Niflumic Acid","Niflumic Acid","D009544",4,0,3,0,13]
["Oxyquinoline","Oxyquinoline","D015125",12,0,3,7,13]
["pentaerythrityl triacrylate","pentaerythrityl triacrylate","C027992",0,0,0,0,13]
["Pentazocine","Pentazocine","D010423",6,0,1,3,13]
["propylparaben","propylparaben","C006068",0,0,0,0,13]
["Ramipril","Ramipril","D017257",6,0,0,0,13]
["Retinaldehyde","Retinaldehyde","D012172",77,9,3,0,13]
["Rubella Vaccine","Rubella Vaccine","D012411",1,0,3,13,13]
["Silver Nitrate","Silver Nitrate","D012835",3,6,1,1,13]
["Squalene","Squalene","D013185",9,15,12,42,13]
["tetrachloroplatinate","tetrachloroplatinate","C036919",1,0,3,3,13]
["tranilast","tranilast","C012293",4,3,3,11,13]
["Triamterene","Triamterene","D014223",8,0,1,1,13]
["Tromethamine","Tromethamine","D014325",16,3,0,0,13]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850",0,32,3,7,12]
["1-Naphthylamine","1-Naphthylamine","D015057",12,0,0,3,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C772,B772)","v":"2-tert-butylhydroquinone"},"2-tert-butylhydroquinone","C018855",9,6,0,8,12]
["4-methoxydalbergione","4-methoxydalbergione","C026198",0,0,0,0,12]
["8,11,14-Eicosatrienoic Acid","8,11,14-Eicosatrienoic Acid","D015126",12,4,0,1,12]
["alclometasone dipropionate","alclometasone dipropionate","C021137",0,0,0,0,12]
["alitretinoin","alitretinoin","C103303",23,15,4,6,12]
["Aluminum Hydroxide","Aluminum Hydroxide","D000536",10,3,32,34,12]
["amorolfine","amorolfine","C038974",0,0,0,0,12]
["apraclonidine","apraclonidine","C016986",1,0,1,0,12]
["Astemizole","Astemizole","D016589",4,0,0,0,12]
["befunolol","befunolol","C006034",0,0,0,0,12]
["benoxaprofen","benoxaprofen","C011677",3,0,0,3,12]
["butantrone","butantrone","C038464",0,0,0,0,12]
["Butylated Hydroxyanisole","Butylated Hydroxyanisole","D002083",13,0,0,3,12]
["Chlortetracycline","Chlortetracycline","D002751",10,0,4,0,12]
["Citalopram","Citalopram","D015283",39,0,0,6,12]
["Colforsin","Colforsin","D005576",27,4,0,26,12]
["Dabigatran","Dabigatran","D000069604",6,0,2,1,12]
["danthron","danthron","C004315",2,0,0,0,12]
["Daunorubicin","Daunorubicin","D003630",68,3,5,44,12]
["Desogestrel","Desogestrel","D017135",5,0,0,0,12]
["Diatrizoate","Diatrizoate","D003973",5,0,0,1,12]
["dibrompropamidine","dibrompropamidine","C053597",0,0,0,0,12]
["Disperse Orange 3","Disperse Orange 3","C041259",0,0,0,0,12]
["Ethoxyquin","Ethoxyquin","D005015",0,0,0,1,12]
["ethylhexylglycerin","ethylhexylglycerin","C524860",0,0,0,0,12]
["Feprazone","Feprazone","D011298",0,0,0,0,12]
["Gutta-Percha","Gutta-Percha","D006171",0,0,1,0,12]
["Haloperidol","Haloperidol","D006220",50,2,3,16,12]
["Halothane","Halothane","D006221",96,0,10,28,12]
["Imipramine","Imipramine","D007099",80,0,1,17,12]
["isothiazolidinone","isothiazolidinone","C512915",0,0,0,6,12]
["lapatinib","lapatinib","C490728",11,4,0,12,12]
["Lignin","Lignin","D008031",50,0,1,9,12]
["Maloprim","Maloprim","C001678",0,0,0,0,12]
["Margarine","Margarine","D008383",0,0,2,0,12]
["Mumps Vaccine","Mumps Vaccine","D009108",0,0,2,18,12]
["N-(3-(dimethylamino)propyl)oleamide","N-(3-(dimethylamino)propyl)oleamide","C044477",0,0,0,0,12]
["Nalidixic Acid","Nalidixic Acid","D009268",18,0,0,3,12]
["Nitrofurantoin","Nitrofurantoin","D009582",14,0,0,4,12]
["Oxprenolol","Oxprenolol","D010096",13,0,0,0,12]
["p-Aminoazobenzene","p-Aminoazobenzene","D010128",4,1,1,0,12]
["pelargonic acid","pelargonic acid","C008776",1,6,1,0,12]
["Pentamidine","Pentamidine","D010419",11,0,6,25,12]
["Phenylethyl Alcohol","Phenylethyl Alcohol","D010626",11,22,3,17,12]
["Phosphorylcholine","Phosphorylcholine","D010767",107,15,31,70,12]
["picric acid","picric acid","C005858",3,0,0,0,12]
["polihexanide","polihexanide","C031233",0,10,0,0,12]
["Prazosin","Prazosin","D011224",39,1,0,3,12]
["Prostaglandins F, Synthetic","Prostaglandins F, Synthetic","D011461",2,0,3,0,12]
["Silicic Acid","Silicic Acid","D012824",4,3,0,1,12]
["silybin","silybin","C440975",12,17,0,8,12]
["Sucrose","Sucrose","D013395",69,9,6,7,12]
["Tego-Betain","Tego-Betain","C065099",0,0,0,0,12]
["Thiabendazole","Thiabendazole","D013827",5,0,0,9,12]
["2,4-Dichlorophenoxyacetic Acid","2,4-Dichlorophenoxyacetic Acid","D015084",21,0,1,25,11]
["3,4-dimethoxydalbergione","3,4-dimethoxydalbergione","C026197",0,0,0,0,11]
["ABO Blood-Group System","ABO Blood-Group System","D000017",48,6,197,35,11]
["Basic Blue 99","Basic Blue 99","C065730",0,0,0,0,11]
["Bet v 1 allergen, Betula","Bet v 1 allergen, Betula","C061312",13,0,10,16,11]
["Betaxolol","Betaxolol","D015784",0,0,0,0,11]
["bifonazole","bifonazole","C036596",1,0,0,0,11]
["carbitol","carbitol","C010111",0,0,0,0,11]
["Carrageenan","Carrageenan","D002351",19,8,6,37,11]
["Carteolol","Carteolol","D002354",2,0,0,0,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C836,B836)","v":"Cefuroxime"},"Cefuroxime","D002444",6,0,0,6,11]
["Cetylpyridinium","Cetylpyridinium","D002594",5,3,0,0,11]
["cinnamyl alcohol","cinnamyl alcohol","C020722",1,0,3,0,11]
["Coconut Oil","Coconut Oil","D000074263",1,0,0,0,11]
["Collodion","Collodion","D003101",20,0,6,0,11]
["Deferoxamine","Deferoxamine","D003676",25,10,0,21,11]
["Desoximetasone","Desoximetasone","D003899",0,0,0,0,11]
["Ethanolamine","Ethanolamine","D019856",1,6,0,1,11]
["etonogestrel","etonogestrel","C044815",5,0,0,0,11]
["falcarinol","falcarinol","C018541",2,3,0,3,11]
["fluindione","fluindione","C017673",0,0,0,0,11]
["Glycyrrhizic Acid","Glycyrrhizic Acid","D019695",26,9,15,47,11]
["hydrazine","hydrazine","C029424",11,3,1,0,11]
["isoalantolactone","isoalantolactone","C032787",0,0,0,0,11]
["Isoflurane","Isoflurane","D007530",29,0,0,3,11]
["isopropyl myristate","isopropyl myristate","C008205",0,0,0,0,11]
["JP5 jet fuel","JP5 jet fuel","C029662",0,3,0,0,11]
["latanoprost","latanoprost","C072042",1,0,3,0,11]
["lime","lime","C016538",0,0,0,0,11]
["maleic acid","maleic acid","C030272",6,0,2,1,11]
["Mannitol","Mannitol","D008353",12,0,4,35,11]
["Mefenamic Acid","Mefenamic Acid","D008528",13,0,0,1,11]
["metabisulfite","metabisulfite","C030981",0,0,0,0,11]
["Methylnitronitrosoguanidine","Methylnitronitrosoguanidine","D008769",5,25,2,12,11]
["Mitoguazone","Mitoguazone","D008935",2,3,0,1,11]
["N-(cyclohexylthio)phthalimide","N-(cyclohexylthio)phthalimide","C052481",0,0,0,0,11]
["nabumetone","nabumetone","C035605",4,0,0,0,11]
["octyl gallate","octyl gallate","C016627",1,0,0,0,11]
["olaquindox","olaquindox","C013168",0,0,0,0,11]
["Parthenium hysterophorus extract","Parthenium hysterophorus extract","C519376",0,0,0,2,11]
["Pentachlorophenol","Pentachlorophenol","D010416",16,0,0,11,11]
["polycaprolactone","polycaprolactone","C016240",13,26,0,0,11]
["potassium bromide","potassium bromide","C039004",4,0,0,0,11]
["Procainamide","Procainamide","D011342",21,0,2,39,11]
["retinol acetate","retinol acetate","C009166",0,0,12,10,11]
["ropivacaine","ropivacaine","C037663",16,13,0,0,11]
["Sildenafil Citrate","Sildenafil Citrate","D000068677",11,0,0,13,11]
["Sodium Benzoate","Sodium Benzoate","D020160",1,0,0,3,11]
["tetramethylthiuram monosulfide","tetramethylthiuram monosulfide","C034033",0,0,0,0,11]
["trimethylolpropane triacrylate","trimethylolpropane triacrylate","C027993",0,0,0,0,11]
["Trinitrobenzenesulfonic Acid","Trinitrobenzenesulfonic Acid","D014302",19,3,8,39,11]
["Uracil","Uracil","D014498",87,4,10,40,11]
["1,6-hexanediol diacrylate","1,6-hexanediol diacrylate","C020355",0,0,0,0,10]
["2,2-bis-(4-(2-methacryloxyethoxy)phenyl)propane","2,2-bis-(4-(2-methacryloxyethoxy)phenyl)propane","C041979",0,0,0,0,10]
["2-phenylphenol","2-phenylphenol","C004369",2,0,0,1,10]
["7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide","7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide","D015123",17,6,1,12,10]
["Acetylglucosamine","Acetylglucosamine","D000117",186,10,9,24,10]
["Adenine","Adenine","D000225",134,19,44,200,10]
["amineptin","amineptin","C011597",0,0,0,0,10]
["Amyl Nitrite","Amyl Nitrite","D000680",0,0,0,3,10]
["anethole","anethole","C006578",1,0,0,3,10]
["apronalide","apronalide","C005700",0,0,0,2,10]
["ascorbate-2-phosphate","ascorbate-2-phosphate","C011669",0,25,0,0,10]
["benz(a)anthracene","benz(a)anthracene","C030935",1,4,0,3,10]
["benzyl benzoate","benzyl benzoate","C006723",1,3,0,0,10]
["bisabolol","bisabolol","C004497",1,0,0,3,10]
["bosentan","bosentan","C086232",3,0,0,6,10]
["Calcium, Dietary","Calcium, Dietary","D002136",15,5,3,3,10]
["Captan","Captan","D002215",1,0,0,0,10]
["Carbon Tetrachloride","Carbon Tetrachloride","D002251",83,0,15,34,10]
["Carticaine","Carticaine","D002355",4,0,0,0,10]
["Cefotaxime","Cefotaxime","D002439",76,0,0,20,10]
["chloroatranol","chloroatranol","C487450",0,1,0,2,10]
["Choline","Choline","D002794",77,7,18,44,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C900,B900)","v":"Citric Acid"},"Citric Acid","D019343",40,9,2,6,10]
["Cyproterone","Cyproterone","D003534",6,0,0,0,10]
["decyl glucoside","decyl glucoside","C504907",0,0,0,0,10]
["deflazacort","deflazacort","C021988",2,0,0,15,10]
["dexchlorpheniramine","dexchlorpheniramine","C018904",0,0,0,0,10]
["Diethylcarbamazine","Diethylcarbamazine","D004049",3,0,7,15,10]
["di-halo","di-halo","C039283",0,0,0,0,10]
["diisononyl phthalate","diisononyl phthalate","C012125",1,0,3,3,10]
["diisopropanolamine","diisopropanolamine","C060040",0,0,0,0,10]
["Dimethoate","Dimethoate","D004117",2,0,0,0,10]
["Dimethylformamide","Dimethylformamide","D004126",3,0,1,1,10]
["diphenylguanidine","diphenylguanidine","C027773",0,0,0,0,10]
["dipivefrin","dipivefrin","C015173",0,0,0,0,10]
["Dipyridamole","Dipyridamole","D004176",22,1,0,17,10]
["ethylbutyl thiourea","ethylbutyl thiourea","C018291",0,0,0,0,10]
["ferrous sulfate","ferrous sulfate","C020748",3,1,0,0,10]
["Fluocortolone","Fluocortolone","D005448",3,0,0,0,10]
["Furazolidone","Furazolidone","D005664",8,0,1,0,10]
["Galactose","Galactose","D005690",232,4,28,27,10]
["gentamicin-polymethylmethacrylate bead","gentamicin-polymethylmethacrylate bead","C030159",0,0,0,0,10]
["Glycogen","Glycogen","D006003",110,5,11,3,10]
["Glyoxal","Glyoxal","D006037",15,7,0,0,10]
["Grape Seed Extract","Grape Seed Extract","D056604",4,6,12,10,10]
["Guanethidine","Guanethidine","D006145",1,0,0,4,10]
["halofuginone","halofuginone","C010176",3,1,0,8,10]
["hydroxypropylcellulose","hydroxypropylcellulose","C008079",0,0,0,0,10]
["hypericin","hypericin","C004965",9,15,3,10,10]
["ibuproxam","ibuproxam","C025377",0,0,0,0,10]
["Indinavir","Indinavir","D019469",9,0,10,44,10]
["liposomal amphotericin B","liposomal amphotericin B","C068538",4,3,1,7,10]
["mancozeb","mancozeb","C013099",2,3,0,1,10]
["Mefloquine","Mefloquine","D015767",10,4,0,4,10]
["melamine","melamine","C011907",2,0,1,0,10]
["Methadone","Methadone","D008691",47,0,0,26,10]
["Methylene Blue","Methylene Blue","D008751",28,3,2,4,10]
["Mexiletine","Mexiletine","D008801",10,0,0,0,10]
["Mupirocin","Mupirocin","D016712",4,1,0,0,10]
["naphthol AS","naphthol AS","C008584",0,0,0,1,10]
["naringenin","naringenin","C005273",14,10,1,5,10]
["nitinol","nitinol","C013616",0,0,0,0,10]
["Nonoxynol","Nonoxynol","D017137",0,0,0,6,10]
["oakmoss","oakmoss","C044724",0,1,0,2,10]
["octenidine","octenidine","C034213",0,6,0,0,10]
["Oleanolic Acid","Oleanolic Acid","D009828",25,21,11,63,10]
["oleyl alcohol","oleyl alcohol","C010268",0,0,0,0,10]
["Ornidazole","Ornidazole","D009950",0,0,0,0,10]
["Osmaron B","Osmaron B","C079524",0,0,0,0,10]
["Oxypurinol","Oxypurinol","D010117",2,0,0,8,10]
["Pancuronium","Pancuronium","D010197",11,0,0,3,10]
["Papaverine","Papaverine","D010208",11,0,0,3,10]
["parthenolide","parthenolide","C002669",14,3,3,12,10]
["Pentobarbital","Pentobarbital","D010424",41,0,0,0,10]
["Phloroglucinol","Phloroglucinol","D010696",14,18,3,9,10]
["quinone","quinone","C004532",38,3,0,6,10]
["sulconazole","sulconazole","C033308",0,0,0,0,10]
["Taurine","Taurine","D013654",42,9,6,16,10]
["temoporfin","temoporfin","C072269",2,0,0,0,10]
["Tenofovir","Tenofovir","D000068698",3,6,5,118,10]
["Tetrodotoxin","Tetrodotoxin","D013779",26,0,2,1,10]
["thioxolone","thioxolone","C009474",0,0,0,0,10]
["Tocainide","Tocainide","D016677",9,0,0,0,10]
["Trioxsalen","Trioxsalen","D014307",4,9,0,13,10]
["triphenyl phosphite","triphenyl phosphite","C013318",0,0,0,0,10]
["Tylosin","Tylosin","D015645",3,0,0,12,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C964,B964)","v":"Venlafaxine Hydrochloride"},"Venlafaxine Hydrochloride","D000069470",5,0,3,7,10]
["Zinc Oxide-Eugenol Cement","Zinc Oxide-Eugenol Cement","D015035",0,1,0,0,10]
["Zinc Sulfate","Zinc Sulfate","D019287",7,3,0,8,10]
["Acrylamide","Acrylamide","D020106",26,9,1,0,9]
["Acrylonitrile","Acrylonitrile","D000181",22,3,3,0,9]
["afloqualone","afloqualone","C033541",0,1,0,6,9]
["alkylbenzyl sulfonic acid","alkylbenzyl sulfonic acid","C030641",0,0,0,0,9]
["Aminoglutethimide","Aminoglutethimide","D000616",4,0,0,0,9]
["Aquavene","Aquavene","C085051",0,0,0,0,9]
["asphalt","asphalt","C006647",1,5,0,1,9]
["basic red 46","basic red 46","C050846",0,0,0,0,9]
["benzylparaben","benzylparaben","C057775",0,0,0,0,9]
["Biopterin","Biopterin","D001708",73,17,4,83,9]
["Brucella Vaccine","Brucella Vaccine","D002004",0,0,17,53,9]
["butyl carbitol","butyl carbitol","C004607",0,0,0,0,9]
["Carbaryl","Carbaryl","D012721",7,0,2,0,9]
["Carbimazole","Carbimazole","D002231",3,0,0,13,9]
["Carmine","Carmine","D002329",0,0,0,0,9]
["Carnitine","Carnitine","D002331",27,3,4,32,9]
["carnosol","carnosol","C068623",0,0,0,0,9]
["Cefazolin","Cefazolin","D002437",61,0,0,0,9]
["cetearyl alcohol","cetearyl alcohol","C419308",0,0,0,0,9]
["Chickenpox Vaccine","Chickenpox Vaccine","D019433",0,0,3,37,9]
["chlorproethazine","chlorproethazine","C054028",0,3,0,0,9]
["Chlorpropamide","Chlorpropamide","D002747",11,0,0,3,9]
["Cycloheximide","Cycloheximide","D003513",17,7,7,30,9]
["Cyclopentolate","Cyclopentolate","D003519",0,0,0,0,9]
["Cyproterone Acetate","Cyproterone Acetate","D017373",2,3,0,1,9]
["decamethrin","decamethrin","C017180",12,0,0,3,9]
["Demeclocycline","Demeclocycline","D003707",7,0,1,0,9]
["Dichlorophen","Dichlorophen","D004003",0,0,0,0,9]
["Dichlorvos","Dichlorvos","D004006",9,3,2,0,9]
["Dimaprit","Dimaprit","D017259",2,0,0,3,9]
["Dimethindene","Dimethindene","D004115",0,0,0,0,9]
["ethylene dimethacrylate","ethylene dimethacrylate","C004919",2,3,0,0,9]
["Fenretinide","Fenretinide","D017313",9,18,4,8,9]
["Fingolimod Hydrochloride","Fingolimod Hydrochloride","D000068876",9,6,58,402,9]
["Flurandrenolone","Flurandrenolone","D005478",0,0,0,0,9]
["furan","furan","C039281",10,0,0,1,9]
["Ginkgo biloba extract","Ginkgo biloba extract","C063170",5,6,2,2,9]
["glycidyl methacrylate","glycidyl methacrylate","C007870",5,0,0,0,9]
["Hesperidin","Hesperidin","D006569",15,6,0,18,9]
["Hirudoid","Hirudoid","C046596",0,0,0,0,9]
["idebenone","idebenone","C036619",1,3,0,0,9]
["Inositol","Inositol","D007294",73,7,3,13,9]
["iopentol","iopentol","C053571",1,0,0,0,9]
["irbesartan","irbesartan","C081309",9,0,0,3,9]
["irinotecan","irinotecan","C051890",15,1,0,8,9]
["Ketamine","Ketamine","D007649",17,0,8,26,9]
["lauryl gallate","lauryl gallate","C008259",0,0,0,0,9]
["lomefloxacin","lomefloxacin","C053091",12,10,0,0,9]
["Losartan","Losartan","D019808",16,0,6,10,9]
["Methane","Methane","D008697",56,0,0,0,9]
["methyl bromide","methyl bromide","C005218",1,0,0,0,9]
["Methylnitrosourea","Methylnitrosourea","D008770",6,6,0,13,9]
["Methylprednisolone Hemisuccinate","Methylprednisolone Hemisuccinate","D008776",1,0,0,1,9]
["Mezlocillin","Mezlocillin","D008802",2,0,0,3,9]
["Norgestrel","Norgestrel","D009644",16,0,0,0,9]
["Novobiocin","Novobiocin","D009675",43,0,0,8,9]
["Okadaic Acid","Okadaic Acid","D019319",23,24,3,41,9]
["perfluorodecalin","perfluorodecalin","C008805",0,0,2,0,9]
["pirfenidone","pirfenidone","C093844",0,0,3,10,9]
["Polyethyleneimine","Polyethyleneimine","D011094",26,10,46,25,9]
["Polytetrafluoroethylene","Polytetrafluoroethylene","D011138",15,2,8,4,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1028,B1028)","v":"ponatinib"},"ponatinib","C545373",13,0,0,0,9]
["Proflavine","Proflavine","D011370",16,3,0,0,9]
["propylene oxide","propylene oxide","C009068",1,0,0,0,9]
["resorcinol monobenzoate","resorcinol monobenzoate","C088024",0,0,0,0,9]
["Ritodrine","Ritodrine","D012312",0,0,0,0,9]
["Roxithromycin","Roxithromycin","D015575",1,19,3,27,9]
["Sitagliptin Phosphate","Sitagliptin Phosphate","D000068900",2,0,0,20,9]
["sodium bisulfite","sodium bisulfite","C009279",0,0,0,3,9]
["sodium fluoride topical preparation","sodium fluoride topical preparation","C023807",0,0,0,0,9]
["sorbitan monooleate","sorbitan monooleate","C018665",0,0,0,0,9]
["Soybean Oil","Soybean Oil","D013024",2,3,0,10,9]
["temozolomide","temozolomide","C047246",9,3,17,25,9]
["temsirolimus","temsirolimus","C401859",1,3,0,0,9]
["Thiamine","Thiamine","D013831",63,0,2,2,9]
["Thioridazine","Thioridazine","D013881",15,0,1,1,9]
["Thromboxane B2","Thromboxane B2","D013929",2,0,0,6,9]
["Trientine","Trientine","D014266",0,0,0,0,9]
["Triprolidine","Triprolidine","D014311",1,0,0,1,9]
["Urethane","Urethane","D014520",15,0,2,12,9]
["usnic acid","usnic acid","C073339",3,9,0,0,9]
["Vincristine","Vincristine","D014750",31,0,7,33,9]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974",1,6,0,0,8]
["2,3,5,6-tetrachloro-4-(methylsulfonyl)pyridine","2,3,5,6-tetrachloro-4-(methylsulfonyl)pyridine","C484946",0,0,0,0,8]
["3-methyl-N,N-diethyl-p-phenylenediamine","3-methyl-N,N-diethyl-p-phenylenediamine","C013740",0,0,0,0,8]
["7-oxodehydroabietic acid","7-oxodehydroabietic acid","C095375",0,0,0,0,8]
["aceclofenac","aceclofenac","C056498",0,1,1,0,8]
["Acetazolamide","Acetazolamide","D000086",29,0,0,0,8]
["Adamantane","Adamantane","D000218",45,0,3,34,8]
["Allergoid","Allergoid","C025536",0,0,8,15,8]
["Amikacin","Amikacin","D000583",14,0,0,3,8]
["Apigenin","Apigenin","D047310",28,54,12,19,8]
["araldite","araldite","C005752",3,0,1,0,8]
["Arbutin","Arbutin","D001104",1,0,0,0,8]
["arsenite","arsenite","C015001",30,95,0,6,8]
["ascaridole","ascaridole","C043372",0,0,4,0,8]
["atranol","atranol","C493895",0,1,0,2,8]
["Bandrowski's base","Bandrowski's base","C051597",1,0,6,13,8]
["benzoxonium chloride","benzoxonium chloride","C013850",0,0,0,0,8]
["Berberine","Berberine","D001599",34,13,12,19,8]
["bexarotene","bexarotene","C095105",6,10,0,30,8]
["Bezafibrate","Bezafibrate","D001629",11,0,0,0,8]
["bisphenol F diglycidyl ether","bisphenol F diglycidyl ether","C423722",0,0,0,0,8]
["Bromocriptine","Bromocriptine","D001971",2,0,0,12,8]
["bryostatin 1","bryostatin 1","C046785",10,16,13,93,8]
["Busulfan","Busulfan","D002066",7,0,5,70,8]
["Butter","Butter","D002079",0,0,0,4,8]
["caffeic acid","caffeic acid","C040048",9,27,0,6,8]
["Calcifediol","Calcifediol","D002112",36,38,10,10,8]
["Calcium Carbonate","Calcium Carbonate","D002119",15,3,1,2,8]
["Calcium Gluconate","Calcium Gluconate","D002125",0,0,0,0,8]
["cefepime","cefepime","C043266",5,0,0,0,8]
["chloramine-T","chloramine-T","C016300",7,0,1,0,8]
["Chlormezanone","Chlormezanone","D002720",2,3,0,0,8]
["Chondroitin","Chondroitin","D002807",40,0,5,1,8]
["Clofazimine","Clofazimine","D002991",6,0,0,10,8]
["Creatinine","Creatinine","D003404",9,3,1,5,8]
["Cytosine","Cytosine","D003596",70,21,10,33,8]
["Danazol","Danazol","D003613",5,0,1,6,8]
["dehydroacetic acid","dehydroacetic acid","C027493",0,0,0,0,8]
["desloratadine","desloratadine","C121345",3,3,0,10,8]
["dibenzo(a,l)pyrene","dibenzo(a,l)pyrene","C041517",2,3,0,0,8]
["dibenzoylmethane","dibenzoylmethane","C061481",1,0,0,0,8]
["diethylenetriamine","diethylenetriamine","C005391",2,0,0,0,8]
["diethyltoluamide, ethanol, glycerin, terpineol, water drug combination","diethyltoluamide, ethanol, glycerin, terpineol, water drug combination","C032866",0,0,0,0,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1092,B1092)","v":"Diphenylamine"},"Diphenylamine","D004159",4,0,0,0,8]
["Disperse Red 1","Disperse Red 1","C069318",0,0,0,0,8]
["Econazole","Econazole","D004464",4,0,0,6,8]
["Eosine Yellowish-(YS)","Eosine Yellowish-(YS)","D004801",18,3,0,0,8]
["Equol","Equol","D060754",5,3,0,8,8]
["Evans Blue","Evans Blue","D005070",8,0,0,3,8]
["Famotidine","Famotidine","D015738",2,0,0,1,8]
["fluocortin butyl ester","fluocortin butyl ester","C011824",0,0,0,0,8]
["glyceryl monostearate","glyceryl monostearate","C048159",0,0,0,0,8]
["Guaiacol","Guaiacol","D006139",6,12,0,1,8]
["Heroin","Heroin","D003932",6,0,0,19,8]
["hexyl cinnamic aldehyde","hexyl cinnamic aldehyde","C080043",0,0,0,0,8]
["isophorone diisocyanate","isophorone diisocyanate","C015301",0,0,0,3,8]
["jojoba wax","jojoba wax","C034743",0,3,0,0,8]
["Kanamycin","Kanamycin","D007612",29,0,1,4,8]
["Ketorolac","Ketorolac","D020910",9,0,0,4,8]
["KH 1060","KH 1060","C074279",3,13,0,6,8]
["lactobionic acid","lactobionic acid","C005608",1,0,0,1,8]
["lead acetate","lead acetate","C008261",5,3,0,20,8]
["Leucovorin","Leucovorin","D002955",17,0,0,14,8]
["Linezolid","Linezolid","D000069349",7,0,0,0,8]
["majantol","majantol","C522135",0,0,0,0,8]
["Masoprocol","Masoprocol","D009637",8,3,3,16,8]
["Meglumine","Meglumine","D008536",8,3,0,10,8]
["Meperidine","Meperidine","D008614",30,0,4,3,8]
["methyl nicotinate","methyl nicotinate","C008473",0,0,0,0,8]
["monomethoxypolyethylene glycol","monomethoxypolyethylene glycol","C028210",10,3,7,23,8]
["Mycophenolic Acid","Mycophenolic Acid","D009173",43,8,80,376,8]
["myrrh oil","myrrh oil","C014119",0,0,0,1,8]
["Neopterin","Neopterin","D019798",0,0,3,84,8]
["neticonazole","neticonazole","C084784",0,0,0,0,8]
["Ninhydrin","Ninhydrin","D009555",1,0,5,0,8]
["nitramine","nitramine","C015384",1,0,0,0,8]
["nordimaprit","nordimaprit","C025838",0,0,0,0,8]
["Nylidrin","Nylidrin","D009756",0,0,0,0,8]
["o-Aminoazotoluene","o-Aminoazotoluene","D009762",2,0,0,0,8]
["o-Phthalaldehyde","o-Phthalaldehyde","D009764",1,0,0,0,8]
["oxaprozin","oxaprozin","C008729",10,0,0,0,8]
["P 1487","P 1487","C040955",0,0,0,0,8]
["palmidrol","palmidrol","C005958",4,13,0,0,8]
["pantoprazole","pantoprazole","C064276",6,0,0,0,8]
["p-Azobenzenearsonate","p-Azobenzenearsonate","D010132",1,0,16,53,8]
["peroxymonosulfate","peroxymonosulfate","C038288",0,0,0,0,8]
["Phenolphthalein","Phenolphthalein","D020113",0,0,0,0,8]
["phthalic anhydride","phthalic anhydride","C043103",0,0,0,3,8]
["pimagedine","pimagedine","C004479",4,3,3,5,8]
["Piracetam","Piracetam","D010889",15,0,0,9,8]
["Poliovirus Vaccine, Oral","Poliovirus Vaccine, Oral","D011055",2,0,10,8,8]
["poly(lactide)","poly(lactide)","C033616",13,9,9,7,8]
["potassium hydroxide","potassium hydroxide","C029943",0,0,0,0,8]
["Propanidid","Propanidid","D011410",4,0,3,0,8]
["Psyllium","Psyllium","D011620",0,0,1,0,8]
["Pyrithioxin","Pyrithioxin","D011746",0,0,0,0,8]
["ragweed pollen","ragweed pollen","C433085",0,0,2,1,8]
["Ritonavir","Ritonavir","D019438",25,3,0,80,8]
["roxatidine acetate","roxatidine acetate","C053742",0,0,0,0,8]
["Salmeterol Xinafoate","Salmeterol Xinafoate","D000068299",5,0,6,18,8]
["Sodium Oxybate","Sodium Oxybate","D012978",8,0,0,3,8]
["sodium sulfite","sodium sulfite","C025026",2,0,0,0,8]
["Soil","Soil","D012987",7,0,0,0,8]
["Spectinomycin","Spectinomycin","D000198",1,0,0,3,8]
["Styrene","Styrene","D020058",10,0,0,9,8]
["Sulfaguanidine","Sulfaguanidine","D013414",0,0,0,0,8]
["sulisobenzone","sulisobenzone","C009361",0,0,0,0,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1156,B1156)","v":"Thioguanine"},"Thioguanine","D013866",7,4,3,72,8]
["Trazodone","Trazodone","D014196",2,0,0,0,8]
["triethylene glycol dimethacrylate","triethylene glycol dimethacrylate","C020946",1,4,0,0,8]
["Trifluoperazine","Trifluoperazine","D014268",31,0,1,19,8]
["Trinitrotoluene","Trinitrotoluene","D014303",6,0,4,0,8]
["ursolic acid","ursolic acid","C005466",8,16,3,15,8]
["Vecuronium Bromide","Vecuronium Bromide","D014673",3,0,0,0,8]
["Vinyl Chloride","Vinyl Chloride","D014752",17,0,0,5,8]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901",1,4,0,3,7]
["2-methoxymethyl-p-phenylenediamine","2-methoxymethyl-p-phenylenediamine","C587181",0,0,3,0,7]
["3,3',4',5-tetrachlorosalicylanilide","3,3',4',5-tetrachlorosalicylanilide","C003390",1,0,1,2,7]
["4-methylcyclohexyl-1,6-dicarboxylic acid anhydride","4-methylcyclohexyl-1,6-dicarboxylic acid anhydride","C051070",0,0,0,0,7]
["acetylacetone","acetylacetone","C008790",2,0,0,0,7]
["afatinib","afatinib","C522924",5,3,0,0,7]
["anastrozole","anastrozole","C090450",1,0,0,0,7]
["azelastine","azelastine","C020976",5,0,3,6,7]
["baicalin","baicalin","C038044",16,13,7,32,7]
["Bendamustine Hydrochloride","Bendamustine Hydrochloride","D000069461",2,0,1,17,7]
["benzanthrone","benzanthrone","C012768",2,0,0,0,7]
["Benzethonium","Benzethonium","D001558",1,0,0,0,7]
["benzonidazole","benzonidazole","C009999",6,0,0,33,7]
["betamethasone dipropionate, calcipotriol drug combination","betamethasone dipropionate, calcipotriol drug combination","C517164",0,0,0,6,7]
["Bimatoprost","Bimatoprost","D000069580",0,0,0,1,7]
["Biotin","Biotin","D001710",416,9,34,28,7]
["bis(tri-n-butyltin)oxide","bis(tri-n-butyltin)oxide","C005961",1,0,3,18,7]
["boric acid","boric acid","C032688",1,0,0,0,7]
["Bumetanide","Bumetanide","D002034",20,0,0,0,7]
["Cadmium Chloride","Cadmium Chloride","D019256",22,7,3,23,7]
["Carbachol","Carbachol","D002217",19,1,3,7,7]
["Carbidopa","Carbidopa","D002230",2,0,0,4,7]
["carboxymethyl-chitosan","carboxymethyl-chitosan","C514968",0,3,1,0,7]
["Cefoperazone","Cefoperazone","D002438",20,0,0,0,7]
["Chlorophyll","Chlorophyll","D002734",159,4,4,13,7]
["Chlorquinaldol","Chlorquinaldol","D002750",0,0,0,0,7]
["cinnabar","cinnabar","C034211",2,0,0,0,7]
["citronellol","citronellol","C007078",0,0,0,4,7]
["clindamycin phosphate","clindamycin phosphate","C007084",1,0,0,0,7]
["clorophene","clorophene","C004660",0,0,0,0,7]
["cypermethrin","cypermethrin","C017160",1,0,0,4,7]
["daidzein","daidzein","C004742",13,12,6,20,7]
["Deanol","Deanol","D003642",1,0,0,0,7]
["Diflunisal","Diflunisal","D004061",32,0,0,0,7]
["efinaconazole","efinaconazole","C431707",0,0,0,0,7]
["Emodin","Emodin","D004642",14,0,6,10,7]
["entecavir","entecavir","C413685",1,0,4,18,7]
["erythromycin, zinc acetate drug combination","erythromycin, zinc acetate drug combination","C050860",0,0,0,0,7]
["Ethyl Biscoumacetate","Ethyl Biscoumacetate","D005017",0,0,0,0,7]
["Etidronic Acid","Etidronic Acid","D012968",3,0,0,8,7]
["etiracetam","etiracetam","C026098",10,0,0,3,7]
["Fenofibrate","Fenofibrate","D011345",9,3,3,5,7]
["Finasteride","Finasteride","D018120",1,1,0,1,7]
["Flumethasone","Flumethasone","D005443",0,0,0,0,7]
["Fluocinonide","Fluocinonide","D005447",0,0,0,5,7]
["Furaldehyde","Furaldehyde","D005662",6,0,1,0,7]
["glycol salicylate","glycol salicylate","C020904",0,0,0,0,7]
["Hydrochloric Acid","Hydrochloric Acid","D006851",6,3,0,0,7]
["Hydroxyethylrutoside","Hydroxyethylrutoside","D006896",2,3,0,0,7]
["Hydroxylamine","Hydroxylamine","D019811",13,3,0,1,7]
["imidazole","imidazole","C029899",50,0,0,3,7]
["Indocyanine Green","Indocyanine Green","D007208",48,7,1,0,7]
["iotrolan","iotrolan","C033300",0,0,1,0,7]
["Ipratropium","Ipratropium","D009241",0,0,0,0,7]
["isoconazole","isoconazole","C020382",0,0,0,0,7]
["iso-sulfan blue","iso-sulfan blue","C025484",0,0,0,0,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1220,B1220)","v":"Ketorolac Tromethamine"},"Ketorolac Tromethamine","D020911",1,0,0,0,7]
["Lactose","Lactose","D007785",126,0,11,4,7]
["lipoxin A4","lipoxin A4","C040527",2,13,7,9,7]
["Mephenesin","Mephenesin","D008615",0,0,0,0,7]
["Methanol","Methanol","D000432",44,0,6,20,7]
["Metoprolol","Metoprolol","D008790",21,0,0,9,7]
["monobenzone","monobenzone","C006429",0,3,1,9,7]
["morniflumate","morniflumate","C027859",0,0,0,0,7]
["mustard oil","mustard oil","C027793",0,0,1,0,7]
["naphtha","naphtha","C004544",0,0,0,0,7]
["Nitrazepam","Nitrazepam","D009567",8,0,0,0,7]
["Nitroprusside","Nitroprusside","D009599",14,3,0,3,7]
["oxybutynin","oxybutynin","C005419",6,0,0,0,7]
["Oxycodone","Oxycodone","D010098",10,0,0,0,7]
["Peanut Oil","Peanut Oil","D000074241",1,0,0,0,7]
["Pentetic Acid","Pentetic Acid","D004369",46,6,4,4,7]
["phenothiazine","phenothiazine","C031637",10,0,0,0,7]
["picolinic acid","picolinic acid","C030614",3,0,0,1,7]
["Poliovirus Vaccine, Inactivated","Poliovirus Vaccine, Inactivated","D011054",0,0,5,6,7]
["Polydioxanone","Polydioxanone","D016687",0,0,0,3,7]
["Potassium Chloride","Potassium Chloride","D011189",34,3,1,1,7]
["Praziquantel","Praziquantel","D011223",3,0,1,23,7]
["prednisolone hemisuccinate","prednisolone hemisuccinate","C021322",2,0,0,1,7]
["proanthocyanidin","proanthocyanidin","C013221",7,21,0,1,7]
["Propane","Propane","D011407",12,0,3,0,7]
["ruscogenin","ruscogenin","C012541",0,0,0,0,7]
["SC 41930","SC 41930","C059950",0,0,0,0,7]
["Sodium Iodide","Sodium Iodide","D012974",7,0,0,4,7]
["sodium thiosulfate","sodium thiosulfate","C017717",4,0,0,0,7]
["sparfloxacin","sparfloxacin","C061363",9,3,0,1,7]
["strontium ranelate","strontium ranelate","C081587",0,0,0,0,7]
["Sulfamethazine","Sulfamethazine","D013418",31,0,0,0,7]
["Sulfobromophthalein","Sulfobromophthalein","D013448",90,0,1,0,7]
["Sumatriptan","Sumatriptan","D018170",2,0,0,3,7]
["Tadalafil","Tadalafil","D000068581",5,3,0,9,7]
["Talaporfin","Talaporfin","C053434",4,0,0,0,7]
["Talc","Talc","D013627",1,0,0,1,7]
["tetraglycidyl-4,4'-methylene dianiline","tetraglycidyl-4,4'-methylene dianiline","C042840",0,0,0,0,7]
["Thromboxane A2","Thromboxane A2","D013928",19,4,4,10,7]
["topiramate","topiramate","C052342",8,0,0,0,7]
["trametinib","trametinib","C560077",2,3,0,10,7]
["Tripelennamine","Tripelennamine","D014309",3,0,0,0,7]
["Tubocurarine","Tubocurarine","D014403",37,0,0,0,7]
["Uric Acid","Uric Acid","D014527",111,5,37,20,7]
["vinyltoluene","vinyltoluene","C027142",0,3,0,0,7]
["Vitallium","Vitallium","D014800",1,0,0,4,7]
["vorinostat","vorinostat","C111237",14,0,10,70,7]
["Zinc Acetate","Zinc Acetate","D019345",1,0,0,3,7]
["1,5-pentanediol","1,5-pentanediol","C578469",0,0,0,0,6]
["1,6-diaminohexane","1,6-diaminohexane","C007297",0,0,0,0,6]
["2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate","2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate","C074712",0,0,0,0,6]
["2,2'-azobis(2-amidinopropane)","2,2'-azobis(2-amidinopropane)","C046728",1,4,0,3,6]
["2,3-oxidosqualene","2,3-oxidosqualene","C002821",1,7,0,0,6]
["2,4,6-tris(dimethylaminomethyl)phenol","2,4,6-tris(dimethylaminomethyl)phenol","C079270",0,0,0,0,6]
["2-aminothiophenol","2-aminothiophenol","C005464",2,0,0,0,6]
["2-butyne-1,4-diol","2-butyne-1,4-diol","C009733",0,0,0,0,6]
["2-dichlorobenzene","2-dichlorobenzene","C004726",3,0,0,0,6]
["2-mercaptoacetate","2-mercaptoacetate","C017487",1,0,0,0,6]
["2-methoxy-4-prop-1-enylphenyl acetate","2-methoxy-4-prop-1-enylphenyl acetate","C400781",0,0,0,0,6]
["4,4-Dimethyl-1,3-oxazolidine, 3,4,4-trimethyl-1,3-oxazolidine drug combination","4,4-Dimethyl-1,3-oxazolidine, 3,4,4-trimethyl-1,3-oxazolidine drug combination","C083031",0,0,0,0,6]
["4',7-dihydroxy-3,4-dihydroisoflavone","4',7-dihydroxy-3,4-dihydroisoflavone","C007610",1,0,0,8,6]
["4-toluenesulfonamide-formaldehyde resin","4-toluenesulfonamide-formaldehyde resin","C027981",0,0,0,0,6]
["6-methylcoumarin","6-methylcoumarin","C018096",1,0,0,0,6]
["Acetaldehyde","Acetaldehyde","D000079",91,9,8,21,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1284,B1284)","v":"acetarsol"},"acetarsol","C005284",0,0,0,0,6]
["acteoside","acteoside","C058956",5,6,1,4,6]
["almond oil","almond oil","C068582",0,0,0,0,6]
["alpha-pinene","alpha-pinene","C005451",0,0,0,0,6]
["Amsacrine","Amsacrine","D000677",16,0,0,2,6]
["Aphidicolin","Aphidicolin","D016590",4,1,0,8,6]
["argan oil","argan oil","C555574",0,0,0,0,6]
["artesunate","artesunate","C039726",4,3,4,22,6]
["AZD 6244","AZD 6244","C517975",2,1,0,4,6]
["bakelite","bakelite","C006682",0,0,0,0,6]
["bamifylline","bamifylline","C006683",1,0,0,0,6]
["benzotriazole","benzotriazole","C012771",2,0,0,3,6]
["cadexomer iodine","cadexomer iodine","C038634",0,0,0,0,6]
["Calcium Oxalate","Calcium Oxalate","D002129",19,0,1,0,6]
["Carbon Monoxide","Carbon Monoxide","D002248",372,1,19,19,6]
["carnauba wax","carnauba wax","C026344",0,0,1,1,6]
["carvedilol","carvedilol","C043211",12,3,0,9,6]
["catechol","catechol","C034221",19,3,1,6,6]
["CD 3 color developer","CD 3 color developer","C041213",0,0,0,0,6]
["CD1a antigen","CD1a antigen","C419393",7,4,83,45,6]
["cefclidin","cefclidin","C056494",4,0,0,0,6]
["ceftiofur","ceftiofur","C053503",1,0,0,0,6]
["Cellulose, Oxidized","Cellulose, Oxidized","D002483",2,0,0,0,6]
["Chalcone","Chalcone","D002599",30,6,0,15,6]
["Chlordiazepoxide","Chlordiazepoxide","D002707",9,0,1,0,6]
["Chlormadinone Acetate","Chlormadinone Acetate","D002715",9,0,0,0,6]
["Chloroform","Chloroform","D002725",28,1,2,1,6]
["Chlorpyrifos","Chlorpyrifos","D004390",21,3,0,19,6]
["chromium sulfate","chromium sulfate","C040874",0,0,0,0,6]
["Cilastatin","Cilastatin","D015377",5,0,0,3,6]
["Cilazapril","Cilazapril","D017315",0,0,0,0,6]
["cisatracurium","cisatracurium","C101584",0,0,0,0,6]
["Clomipramine","Clomipramine","D002997",5,0,0,18,6]
["costunolide","costunolide","C002602",0,3,0,3,6]
["croconazole","croconazole","C038008",0,0,0,0,6]
["cumene hydroperoxide","cumene hydroperoxide","C007164",1,4,0,3,6]
["Cystamine","Cystamine","D003538",7,0,1,10,6]
["dazomet","dazomet","C012864",0,0,0,0,6]
["deferiprone","deferiprone","C044919",7,0,0,10,6]
["dexketoprofen trometamol","dexketoprofen trometamol","C118296",0,0,0,0,6]
["Dextromethorphan","Dextromethorphan","D003915",6,0,3,11,6]
["Dicumarol","Dicumarol","D001728",49,0,4,0,6]
["diisodecyl phthalate","diisodecyl phthalate","C042080",0,0,0,0,6]
["diisopropyl sebacate","diisopropyl sebacate","C050859",0,0,0,0,6]
["dioctyl maleate","dioctyl maleate","C484947",0,0,0,0,6]
["Dobutamine","Dobutamine","D004280",1,0,0,3,6]
["donepezil","donepezil","C076946",11,0,0,3,6]
["Ellagic Acid","Ellagic Acid","D004610",3,12,3,8,6]
["Engerix-B","Engerix-B","C075654",0,0,1,7,6]
["eperisone","eperisone","C030848",0,0,0,0,6]
["Ether","Ether","D004986",5,0,2,0,6]
["Ethylene Chlorohydrin","Ethylene Chlorohydrin","D005023",3,3,0,0,6]
["Ethylmercuric Chloride","Ethylmercuric Chloride","D005034",1,0,0,0,6]
["etravirine","etravirine","C451734",6,0,1,2,6]
["fabric softeners","fabric softeners","C010153",0,0,0,0,6]
["Febuxostat","Febuxostat","D000069465",3,0,0,0,6]
["Foscarnet","Foscarnet","D017245",5,0,0,15,6]
["frullanolide","frullanolide","C007787",0,0,0,0,6]
["fucoidan","fucoidan","C007789",34,6,16,28,6]
["Gallamine Triethiodide","Gallamine Triethiodide","D005703",4,0,0,0,6]
["gingerol","gingerol","C007845",3,3,0,10,6]
["glyceryl-1-monoabietate","glyceryl-1-monoabietate","C089620",0,0,0,0,6]
["glycidyl trimethylammonium","glycidyl trimethylammonium","C045006",0,0,0,0,6]
["gold chloride","gold chloride","C038016",0,0,0,3,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1348,B1348)","v":"Granuflex E"},"Granuflex E","C087325",0,0,0,0,6]
["Hexachlorobenzene","Hexachlorobenzene","D006581",1,0,0,19,6]
["Hioxyl","Hioxyl","C051288",0,0,0,0,6]
["histamine phosphate","histamine phosphate","C027556",0,0,0,0,6]
["Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18","Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18","D000068857",0,1,0,9,6]
["Indapamide","Indapamide","D007190",2,0,0,0,6]
["Iothalamic Acid","Iothalamic Acid","D007483",9,0,0,0,6]
["isoborneol","isoborneol","C022871",2,3,0,0,6]
["isopalmityl diglyceryl sebacate","isopalmityl diglyceryl sebacate","C400264",0,0,0,0,6]
["Isothiuronium","Isothiuronium","D007550",3,3,0,0,6]
["juglone","juglone","C005134",2,6,0,0,6]
["Lipid A","Lipid A","D008050",59,3,122,148,6]
["Lithium Chloride","Lithium Chloride","D018021",12,0,9,19,6]
["Luteolin","Luteolin","D047311",32,32,1,11,6]
["Magnesium Chloride","Magnesium Chloride","D015636",15,1,0,0,6]
["Materia Medica","Materia Medica","D008419",1,3,6,10,6]
["meglumine antimoniate","meglumine antimoniate","C005278",0,0,0,7,6]
["methacrylic acid","methacrylic acid","C008384",2,1,0,0,6]
["methylene diisocyanate","methylene diisocyanate","C059330",0,0,0,0,6]
["monoolein","monoolein","C005953",1,0,0,0,6]
["myristyl alcohol","myristyl alcohol","C020940",0,0,0,0,6]
["naphthalene","naphthalene","C031721",24,0,4,4,6]
["naphthenic acid","naphthenic acid","C046170",1,0,0,3,6]
["Nestosyl ointment","Nestosyl ointment","C030643",0,0,0,0,6]
["N-hydroxyphthalimide","N-hydroxyphthalimide","C037437",0,0,0,0,6]
["N-phenyl-1-naphthylamine","N-phenyl-1-naphthylamine","C005444",1,0,0,0,6]
["octyl dodecanol","octyl dodecanol","C456972",0,0,0,0,6]
["olipifat","olipifat","C413426",0,0,0,3,6]
["pamabrom","pamabrom","C069987",0,0,0,0,6]
["Paramethasone","Paramethasone","D010248",1,0,1,0,6]
["Paromomycin","Paromomycin","D010303",15,0,3,1,6]
["pederin","pederin","C100127",0,0,0,0,6]
["Penicillin G Procaine","Penicillin G Procaine","D010402",1,0,0,0,6]
["perflubron","perflubron","C003072",0,0,0,0,6]
["Phenylpropanolamine","Phenylpropanolamine","D010665",5,0,0,0,6]
["pholcodine","pholcodine","C008872",0,0,0,0,6]
["piketoprofen","piketoprofen","C048832",0,0,0,0,6]
["Pirenzepine","Pirenzepine","D010890",8,0,0,4,6]
["Polyhydroxyethyl Methacrylate","Polyhydroxyethyl Methacrylate","D011102",16,10,3,7,6]
["Prasugrel Hydrochloride","Prasugrel Hydrochloride","D000068799",2,0,0,1,6]
["propacetamol","propacetamol","C063776",0,0,0,0,6]
["Propoxycaine","Propoxycaine","D011430",0,0,0,0,6]
["Prostaglandins D","Prostaglandins D","D011457",5,0,3,5,6]
["pyridine","pyridine","C023666",39,0,1,2,6]
["Pyrilamine","Pyrilamine","D011738",7,0,0,2,6]
["Raloxifene Hydrochloride","Raloxifene Hydrochloride","D020849",13,0,3,9,6]
["rosmarinic acid","rosmarinic acid","C041376",7,12,6,17,6]
["salicyl alcohol","salicyl alcohol","C010631",0,0,0,0,6]
["Saline Solution, Hypertonic","Saline Solution, Hypertonic","D012462",1,3,0,19,6]
["sapropterin","sapropterin","C003402",62,14,0,12,6]
["Sewage","Sewage","D012722",9,0,3,9,6]
["Simethicone","Simethicone","D012841",0,0,0,0,6]
["Sodium Salicylate","Sodium Salicylate","D012980",38,0,12,4,6]
["Sodium, Dietary","Sodium, Dietary","D012982",2,0,1,2,6]
["sphingosine phosphorylcholine","sphingosine phosphorylcholine","C005356",7,9,4,13,6]
["Sulfisoxazole","Sulfisoxazole","D013444",31,0,0,3,6]
["Sunflower Oil","Sunflower Oil","D000074242",0,0,3,6,6]
["Temazepam","Temazepam","D013693",7,0,0,0,6]
["Terazosin","Terazosin","C041226",3,1,0,0,6]
["terephthalylidene dicamphor sulfonic acid","terephthalylidene dicamphor sulfonic acid","C075352",0,0,0,0,6]
["tetraethylene glycol diacrylate","tetraethylene glycol diacrylate","C032704",0,0,0,0,6]
["Thiamphenicol","Thiamphenicol","D013839",9,0,0,1,6]
["Thiotepa","Thiotepa","D013852",2,0,2,6,6]
["treprostinil","treprostinil","C427248",2,0,7,3,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1412,B1412)","v":"triphenyl phosphate"},"triphenyl phosphate","C005445",0,0,3,0,6]
["Tropolone","Tropolone","D014334",11,5,1,5,6]
["tuliposide A","tuliposide A","C062516",0,0,0,0,6]
["Vanillic Acid","Vanillic Acid","D014641",6,4,0,12,6]
["Ves v 5 allergen","Ves v 5 allergen","C431905",0,0,0,2,6]
["Vitamin K 3","Vitamin K 3","D024483",13,6,0,4,6]
["Xylitol","Xylitol","D014993",5,0,0,1,6]
["Yellow Fever Vaccine","Yellow Fever Vaccine","D022341",0,0,18,61,6]
["zafirlukast","zafirlukast","C062735",1,0,0,0,6]
["Ziram","Ziram","D015039",0,0,0,1,6]
["zoledronic acid","zoledronic acid","C088658",7,28,38,126,6]
["Zymosan","Zymosan","D015054",15,3,46,15,6]
["1,4-bis(2,3-epoxypropoxy)butane","1,4-bis(2,3-epoxypropoxy)butane","C014376",0,0,0,0,5]
["1,6-hexanediol diglycidyl ether","1,6-hexanediol diglycidyl ether","C414962",0,0,0,0,5]
["10-acetoxy-8,9-epoxythymol isobutyrate","10-acetoxy-8,9-epoxythymol isobutyrate","C057029",0,0,0,0,5]
["2-(2',4'-diaminophenoxy)ethanol","2-(2',4'-diaminophenoxy)ethanol","C032556",0,0,0,0,5]
["2,4-dinitrothiocyanatobenzene","2,4-dinitrothiocyanatobenzene","C010936",4,3,1,1,5]
["2-ethylhexyl acrylate","2-ethylhexyl acrylate","C036758",0,0,0,0,5]
["2-pentylcinnamic alcohol","2-pentylcinnamic alcohol","C037029",0,0,0,0,5]
["3-hexenyl salicylate","3-hexenyl salicylate","C023006",0,0,0,0,5]
["4-(1-phenylethyl)-1,3-benzenediol","4-(1-phenylethyl)-1,3-benzenediol","C512391",0,0,0,0,5]
["4,4',6-trimethylangelicin","4,4',6-trimethylangelicin","C041621",4,3,3,0,5]
["4,7-dichloroquinoline","4,7-dichloroquinoline","C035317",0,0,0,0,5]
["4-aminophenol","4-aminophenol","C026729",3,0,3,3,5]
["4-tert-octylphenol","4-tert-octylphenol","C105260",2,0,0,3,5]
["acephate","acephate","C001969",1,0,0,2,5]
["acetylcellulose","acetylcellulose","C005062",3,0,3,6,5]
["acid citrate dextrose","acid citrate dextrose","C002113",1,0,0,3,5]
["Alfentanil","Alfentanil","D015760",20,0,0,0,5]
["Allantoin","Allantoin","D000481",3,0,0,0,5]
["allergen Can f I","allergen Can f I","C091462",1,0,4,9,5]
["allyl sulfide","allyl sulfide","C038491",5,3,0,3,5]
["alpha-Linolenic Acid","alpha-Linolenic Acid","D017962",4,0,0,11,5]
["Aminopropionitrile","Aminopropionitrile","D000629",2,0,0,0,5]
["Ammonium Hydroxide","Ammonium Hydroxide","D064753",0,0,0,0,5]
["Amoxapine","Amoxapine","D000657",2,0,0,0,5]
["anandamide","anandamide","C078814",38,17,10,17,5]
["andrographolide","andrographolide","C030419",15,0,3,15,5]
["antigen 85B, Mycobacterium leprae","antigen 85B, Mycobacterium leprae","C071448",2,0,1,7,5]
["artemether","artemether","C032942",8,0,0,6,5]
["astragaloside A","astragaloside A","C052064",3,4,0,3,5]
["Benomyl","Benomyl","D001542",0,0,0,0,5]
["Bentonite","Bentonite","D001546",4,6,2,6,5]
["Benzoin","Benzoin","D001573",1,0,0,0,5]
["benzophenone","benzophenone","C047723",9,6,0,0,5]
["benzoporphyrin D","benzoporphyrin D","C504224",1,3,3,7,5]
["benzyl salicylate","benzyl salicylate","C039672",2,0,0,0,5]
["bergamot oil","bergamot oil","C068336",0,0,0,0,5]
["beta-thujaplicin","beta-thujaplicin","C009479",3,5,0,3,5]
["Biobrane","Biobrane","C042816",0,2,0,0,5]
["Bupranolol","Bupranolol","D002046",2,0,0,0,5]
["butyl diglycol acetate","butyl diglycol acetate","C061482",0,0,0,0,5]
["Butyric Acid","Butyric Acid","D020148",8,14,4,36,5]
["calcium lignosulfonate","calcium lignosulfonate","C000353",0,0,0,0,5]
["Calcium Sulfate","Calcium Sulfate","D002133",0,3,0,0,5]
["carboxypolymethylene","carboxypolymethylene","C006912",0,0,1,1,5]
["Cefadroxil","Cefadroxil","D002434",1,0,0,0,5]
["cefcapene pivoxil hydrochloride","cefcapene pivoxil hydrochloride","C425944",0,0,0,0,5]
["Cephaloridine","Cephaloridine","D002509",11,0,1,0,5]
["Chlorfenvinphos","Chlorfenvinphos","D002709",1,0,0,0,5]
["chloroacetic acid","chloroacetic acid","C006972",2,0,0,0,5]
["Chlorprothixene","Chlorprothixene","D002749",1,0,0,0,5]
["chromic chloride","chromic chloride","C022990",4,0,0,0,5]
["cocoamidopropylbetaine","cocoamidopropylbetaine","C503172",0,0,0,0,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1476,B1476)","v":"Cod Liver Oil"},"Cod Liver Oil","D003060",0,0,3,0,5]
["cresyl glycidyl ether","cresyl glycidyl ether","C046242",0,0,0,0,5]
["Decubal","Decubal","C067462",0,0,0,0,5]
["Dental Porcelain","Dental Porcelain","D003776",0,2,0,0,5]
["Deoxycholic Acid","Deoxycholic Acid","D003840",46,6,2,7,5]
["Deoxyglucose","Deoxyglucose","D003847",18,3,0,46,5]
["diacetazotol","diacetazotol","C029040",0,0,0,0,5]
["Diazinon","Diazinon","D003976",1,0,0,8,5]
["Dietary Fiber","Dietary Fiber","D004043",5,0,14,11,5]
["diethyl phthalate","diethyl phthalate","C007379",0,0,1,3,5]
["Diflucortolone","Diflucortolone","D004060",0,0,0,0,5]
["Digoxin","Digoxin","D004077",159,0,31,4,5]
["Diosgenin","Diosgenin","D004144",4,3,0,0,5]
["diperodon","diperodon","C027013",0,0,0,0,5]
["Diphtheria-Tetanus Vaccine","Diphtheria-Tetanus Vaccine","D022422",0,0,1,7,5]
["Disperse Orange 1","Disperse Orange 1","C556349",0,0,0,0,5]
["dodecyl sulfate","dodecyl sulfate","C028913",2,0,0,0,5]
["edatrexate","edatrexate","C040210",0,0,0,0,5]
["enprofylline","enprofylline","C034347",8,0,0,0,5]
["ethylene","ethylene","C036216",69,0,0,2,5]
["ethylphenylpropiolate","ethylphenylpropiolate","C015202",0,0,0,0,5]
["ferric chloride","ferric chloride","C024555",6,3,3,1,5]
["ferric oxide","ferric oxide","C000499",30,3,33,26,5]
["ferulic acid","ferulic acid","C004999",12,3,0,0,5]
["Flunarizine","Flunarizine","D005444",2,0,0,1,5]
["Fluprednisolone","Fluprednisolone","D005477",2,0,0,0,5]
["Foral 85","Foral 85","C041216",0,0,0,0,5]
["fumarprotocetraric acid","fumarprotocetraric acid","C026307",0,0,0,0,5]
["Gabexate","Gabexate","D016670",3,0,0,0,5]
["Gasoline","Gasoline","D005742",0,3,2,3,5]
["gatifloxacin","gatifloxacin","C078049",3,0,0,0,5]
["geranylgeranylhydroquinone","geranylgeranylhydroquinone","C026300",0,0,0,0,5]
["geranylhydroquinone","geranylhydroquinone","C026301",0,0,0,0,5]
["ginkgolide B","ginkgolide B","C045856",5,0,5,12,5]
["Glucaric Acid","Glucaric Acid","D005937",5,0,0,0,5]
["glycolide E-caprolactone copolymer","glycolide E-caprolactone copolymer","C095495",0,0,0,0,5]
["Grape Seed Proanthocyanidins","Grape Seed Proanthocyanidins","C511402",1,3,12,10,5]
["Gum Arabic","Gum Arabic","D006170",5,0,1,2,5]
["Heme","Heme","D006418",1042,3,10,14,5]
["hexamidine","hexamidine","C018961",0,0,0,0,5]
["Hydrogen Sulfide","Hydrogen Sulfide","D006862",16,25,0,13,5]
["Hydromorphone","Hydromorphone","D004091",4,0,0,0,5]
["icotinib","icotinib","C531470",2,0,0,0,5]
["Ifosfamide","Ifosfamide","D007069",4,0,7,9,5]
["indole-3-carbinol","indole-3-carbinol","C016517",11,8,3,15,5]
["Iodized Oil","Iodized Oil","D007459",5,0,3,1,5]
["iodoantipyrine","iodoantipyrine","C008135",0,0,0,3,5]
["isothiocyanic acid","isothiocyanic acid","C037152",2,1,1,0,5]
["Isoxsuprine","Isoxsuprine","D007556",1,0,0,0,5]
["lauric acid","lauric acid","C030358",12,1,3,1,5]
["Ledermix","Ledermix","C001527",0,0,0,0,5]
["loxoprofen","loxoprofen","C040656",0,0,0,0,5]
["lysophosphatidic acid","lysophosphatidic acid","C032881",27,17,7,23,5]
["Magnesium Sulfate","Magnesium Sulfate","D008278",2,0,1,0,5]
["Malondialdehyde","Malondialdehyde","D008315",27,9,8,17,5]
["manganese chloride","manganese chloride","C025340",6,1,0,5,5]
["Mannose","Mannose","D008358",169,3,91,56,5]
["Maprotiline","Maprotiline","D008376",6,0,1,6,5]
["Mastic Resin","Mastic Resin","D000069997",2,0,0,0,5]
["Meprobamate","Meprobamate","D008620",3,0,0,0,5]
["Methohexital","Methohexital","D008723",6,0,0,3,5]
["Methoxychlor","Methoxychlor","D008731",2,0,0,9,5]
["methyldithiocarbamate","methyldithiocarbamate","C008435",0,0,0,0,5]
["Mitoxantrone","Mitoxantrone","D008942",18,3,10,26,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1540,B1540)","v":"mizolastine"},"mizolastine","C076170",0,3,0,3,5]
["monophosphoryl lipid A","monophosphoryl lipid A","C048436",1,3,60,84,5]
["musk","musk","C008563",0,1,0,2,5]
["N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine","N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine","C452423",4,0,0,0,5]
["neamine","neamine","C488396",3,0,0,0,5]
["neem oil","neem oil","C002443",0,0,0,0,5]
["nicotinic acid benzyl ester","nicotinic acid benzyl ester","C025653",1,0,0,0,5]
["nifuroxazide","nifuroxazide","C013150",0,0,1,0,5]
["Nimodipine","Nimodipine","D009553",2,0,0,0,5]
["nitrazine yellow","nitrazine yellow","C013617",0,0,1,0,5]
["N-methylol-chloracetamide","N-methylol-chloracetamide","C022087",0,0,0,0,5]
["N-methylpyrrolidone","N-methylpyrrolidone","C038678",2,0,1,0,5]
["nobiletin","nobiletin","C008661",8,3,0,3,5]
["norflurane","norflurane","C063006",0,0,0,0,5]
["orlistat","orlistat","C055122",4,0,0,0,5]
["oxcarbamazepine","oxcarbamazepine","C476610",1,0,0,0,5]
["Oxidopamine","Oxidopamine","D016627",15,0,3,11,5]
["ozagrel","ozagrel","C034364",2,0,0,0,5]
["ozenoxacin","ozenoxacin","C000592413",0,0,0,0,5]
["panduratin A","panduratin A","C482884",2,0,0,0,5]
["Perphenazine","Perphenazine","D010546",3,0,0,0,5]
["Phosgene","Phosgene","D010705",3,0,0,0,5]
["piperacillin, tazobactam drug combination","piperacillin, tazobactam drug combination","C085143",0,0,2,0,5]
["Podophyllin","Podophyllin","D011033",0,3,0,3,5]
["Polyethylene","Polyethylene","D020959",10,0,0,0,5]
["polygodial","polygodial","C034380",0,0,0,0,5]
["polyurethane foam","polyurethane foam","C028279",1,0,0,0,5]
["polyvinylmethoxyethylene-maleic anhydride copolymer","polyvinylmethoxyethylene-maleic anhydride copolymer","C058026",1,0,0,0,5]
["Potassium Permanganate","Potassium Permanganate","D011196",5,1,0,0,5]
["prednisolone acetate","prednisolone acetate","C009935",0,0,0,0,5]
["Prochlorperazine","Prochlorperazine","D011346",1,0,0,0,5]
["Prodigiozan","Prodigiozan","D011354",0,0,2,6,5]
["propicillin","propicillin","C100135",0,0,0,0,5]
["propionic acid","propionic acid","C029658",2,1,0,1,5]
["Pseudoephedrine","Pseudoephedrine","D054199",2,0,0,1,5]
["pullulan","pullulan","C009109",5,1,12,15,5]
["pyrimidine","pyrimidine","C030986",44,0,0,12,5]
["Reserpine","Reserpine","D012110",20,0,2,8,5]
["retapamulin","retapamulin","C508887",0,0,0,0,5]
["Rhamnose","Rhamnose","D012210",16,6,2,5,5]
["rhododendrol","rhododendrol","C115945",0,0,0,3,5]
["rifamycin SV","rifamycin SV","C023808",3,0,0,6,5]
["Risperidone","Risperidone","D018967",17,0,3,7,5]
["rocuronium","rocuronium","C061870",1,0,0,0,5]
["rotigotine","rotigotine","C047508",2,0,0,0,5]
["Saquinavir","Saquinavir","D019258",14,0,1,43,5]
["Scarlet Red","Scarlet Red","C009213",1,0,0,0,5]
["scutan","scutan","C019085",0,0,0,0,5]
["Sodium Bicarbonate","Sodium Bicarbonate","D017693",4,3,0,0,5]
["sodium laureth sulfate","sodium laureth sulfate","C408148",0,0,0,0,5]
["Solutan","Solutan","C032875",0,0,0,0,5]
["sorbinil","sorbinil","C026411",4,0,0,0,5]
["Sorbitol","Sorbitol","D013012",15,6,3,0,5]
["stearic acid","stearic acid","C031183",10,3,1,9,5]
["Sugammadex","Sugammadex","C453980",0,0,0,0,5]
["Sulfamethoxypyridazine","Sulfamethoxypyridazine","D013421",17,0,2,0,5]
["Sulfur Dioxide","Sulfur Dioxide","D013458",5,0,0,0,5]
["suplatast tosilate","suplatast tosilate","C073028",0,0,18,10,5]
["tamsulosin","tamsulosin","C088482",12,0,0,0,5]
["teleocidins","teleocidins","C022176",3,0,0,8,5]
["thiocyanic acid","thiocyanic acid","C026976",0,0,0,0,5]
["tiaprofenic acid","tiaprofenic acid","C021270",6,1,0,0,5]
["tinzaparin","tinzaparin","C081247",3,0,0,0,5]
["Tolazoline","Tolazoline","D014043",1,0,0,0,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1604,B1604)","v":"triethanolamine stearate"},"triethanolamine stearate","C015555",0,0,0,0,5]
["triflusal","triflusal","C016167",4,0,0,0,5]
["triglycidyl-p-aminophenol","triglycidyl-p-aminophenol","C414224",0,0,0,0,5]
["Tropicamide","Tropicamide","D014331",1,0,0,0,5]
["Tyramine","Tyramine","D014439",25,1,4,5,5]
["vanillin","vanillin","C100058",8,3,0,0,5]
["Varenicline","Varenicline","D000068580",9,0,0,0,5]
["Vitamin B 6","Vitamin B 6","D025101",6,1,0,2,5]
["warburganal","warburganal","C037080",0,0,0,0,5]
["xylosides","xylosides","C010807",1,6,1,0,5]
["Zinostatin","Zinostatin","D009353",18,0,2,7,5]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159",8,7,0,0,5]
["(+,-)-1-cyclohexyl-4-(1,2-diphenylethyl)piperazine","(+,-)-1-cyclohexyl-4-(1,2-diphenylethyl)piperazine","C012631",0,0,0,0,4]
["1,1,1-trichloroethane","1,1,1-trichloroethane","C024566",2,0,0,0,4]
["1,1-dimethylallyl caffeic acid ester","1,1-dimethylallyl caffeic acid ester","C054126",0,0,0,0,4]
["1,2-cyclohexanediamine","1,2-cyclohexanediamine","C030435",2,0,0,0,4]
["1,2-dioctanoylglycerol","1,2-dioctanoylglycerol","C044295",0,0,0,10,4]
["1,3-diisopropylcarbodiimide","1,3-diisopropylcarbodiimide","C081611",0,0,0,0,4]
["1,3-dimethylol-5,5-dimethylhydantoin","1,3-dimethylol-5,5-dimethylhydantoin","C056057",0,0,0,0,4]
["1,3-xylenediamine","1,3-xylenediamine","C066883",0,0,0,0,4]
["13,14-epoxyabietic acid","13,14-epoxyabietic acid","C104668",0,0,0,0,4]
["15-hydroperoxyabietic acid","15-hydroperoxyabietic acid","C055834",0,0,0,0,4]
["1-myristylpicolinium","1-myristylpicolinium","C054770",0,0,0,0,4]
["1-phenylazo-2-naphthol","1-phenylazo-2-naphthol","C024336",0,0,0,0,4]
["2,2',4,4'-tetrahydroxybenzophenone","2,2',4,4'-tetrahydroxybenzophenone","C035476",0,0,0,0,4]
["2,2'-bisphenol F","2,2'-bisphenol F","C047969",0,0,0,0,4]
["2,2-di(4-methacryloxyphenyl)propane","2,2-di(4-methacryloxyphenyl)propane","C002462",0,0,0,0,4]
["2,2'-dihydroxy-5,5'-dipropylbiphenyl","2,2'-dihydroxy-5,5'-dipropylbiphenyl","C486798",0,0,0,0,4]
["2,4'-bisphenol F","2,4'-bisphenol F","C047971",0,0,0,0,4]
["2,4-diamino-6-chloromethylpteridine","2,4-diamino-6-chloromethylpteridine","C065370",0,0,0,0,4]
["2,4-dinitrofluorobenzene sulfonic acid","2,4-dinitrofluorobenzene sulfonic acid","C045305",0,0,4,4,4]
["2,6-dimethoxy-1,4-benzoquinone","2,6-dimethoxy-1,4-benzoquinone","C030511",0,0,0,2,4]
["2-chloromethyl-4-phenyl-6-chloroquinazoline-3-oxide","2-chloromethyl-4-phenyl-6-chloroquinazoline-3-oxide","C050843",0,0,0,0,4]
["2-ethylhexylzinc dithiophosphate","2-ethylhexylzinc dithiophosphate","C425943",0,0,0,0,4]
["2-hydroxyethyl acrylate","2-hydroxyethyl acrylate","C035957",0,0,0,0,4]
["2-hydroxypropyl methacrylate","2-hydroxypropyl methacrylate","C029639",0,0,0,0,4]
["2-methyl-4,5-trimethylene-4-isothiazolin-3-one","2-methyl-4,5-trimethylene-4-isothiazolin-3-one","C087314",0,0,0,0,4]
["2-naphthol","2-naphthol","C028405",1,0,0,0,4]
["2-vinylpyridine","2-vinylpyridine","C030953",0,0,0,0,4]
["3-(aminomethyl)pyridyl salicylate","3-(aminomethyl)pyridyl salicylate","C053224",0,0,0,0,4]
["3-(hydroxyethyl)-5-methyl-8-(2-methylethyl)-3,4-dihydro-2H-1,3-benzoxazine","3-(hydroxyethyl)-5-methyl-8-(2-methylethyl)-3,4-dihydro-2H-1,3-benzoxazine","C051780",0,0,0,0,4]
["3-(-methoxyphenyl)glycidic acid methylester","3-(-methoxyphenyl)glycidic acid methylester","C055263",0,0,0,0,4]
["3-carbethoxypsoralen","3-carbethoxypsoralen","C017104",2,0,0,0,4]
["3-carene","3-carene","C030218",1,0,0,0,4]
["3-O-ethylascorbic acid","3-O-ethylascorbic acid","C000594008",0,0,0,0,4]
["4-(2-((12-hydroxy-1-oxo-9-octadecenyl)amino)ethyl) ester-sulfobutanedioic acid","4-(2-((12-hydroxy-1-oxo-9-octadecenyl)amino)ethyl) ester-sulfobutanedioic acid","C063597",0,0,0,0,4]
["4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene-1-imidazolylacetonitrile","4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene-1-imidazolylacetonitrile","C112528",1,0,0,0,4]
["4,4'-bisphenol F","4,4'-bisphenol F","C008745",2,0,0,0,4]
["4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one","4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one","C500007",0,0,0,0,4]
["4-amino-N-ethyl-N-(beta-hydroxy-ethyl)-m-toluidine","4-amino-N-ethyl-N-(beta-hydroxy-ethyl)-m-toluidine","C041977",0,0,0,0,4]
["4-chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester","4-chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester","C527120",0,0,0,0,4]
["4-nitrobenzyl bromide","4-nitrobenzyl bromide","C027563",0,0,0,0,4]
["4-nonylphenol","4-nonylphenol","C041594",3,0,6,3,4]
["4-vinylpyridine","4-vinylpyridine","C029351",0,0,0,0,4]
["5-((2-aminoethyl)thiomethyl)-N,N-dimethyl-2-furanmethanamine","5-((2-aminoethyl)thiomethyl)-N,N-dimethyl-2-furanmethanamine","C040001",0,0,0,0,4]
["5-ethyl-1-aza-3,7-dioxabicyclo-3.3.0-octane","5-ethyl-1-aza-3,7-dioxabicyclo-3.3.0-octane","C040954",0,0,0,0,4]
["6-(5-chloro-2-methoxybenzyl)-4-alarkylaminocarbonyl-1,4-diazepane-2,5-dione","6-(5-chloro-2-methoxybenzyl)-4-alarkylaminocarbonyl-1,4-diazepane-2,5-dione","C538783",0,0,0,0,4]
["6-methyl-2-ethyl-3-hydroxypyridine","6-methyl-2-ethyl-3-hydroxypyridine","C009820",1,0,0,0,4]
["7H-dibenzo(c,g)carbazole","7H-dibenzo(c,g)carbazole","C013478",1,6,0,0,4]
["8-epi-prostaglandin F2alpha","8-epi-prostaglandin F2alpha","C075750",4,0,0,0,4]
["acetotartaric acid","acetotartaric acid","C041214",0,0,0,0,4]
["acetyl acetonate","acetyl acetonate","C049529",0,0,0,0,4]
["Acid Blue 158","Acid Blue 158","C107194",0,0,0,0,4]
["acrivastine","acrivastine","C043648",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1668,B1668)","v":"adipostatin A"},"adipostatin A","C041328",0,0,0,0,4]
["alachlor","alachlor","C000188",1,0,0,0,4]
["alclofenac epoxide","alclofenac epoxide","C025212",0,0,0,0,4]
["Alphacopal","Alphacopal","C062046",0,0,0,0,4]
["alpha-peroxyachifolid","alpha-peroxyachifolid","C070257",0,0,0,0,4]
["alpha-phenylindole","alpha-phenylindole","C026570",0,0,0,0,4]
["aluminum acetate","aluminum acetate","C013396",0,0,0,0,4]
["aluminum sulfate","aluminum sulfate","C041524",0,0,23,33,4]
["aluminum tetrasulfophthalocyanine","aluminum tetrasulfophthalocyanine","C048577",0,3,0,0,4]
["aminoquinuride","aminoquinuride","C010850",0,0,0,3,4]
["Ammonium Chloride","Ammonium Chloride","D000643",2,0,4,9,4]
["ampiroxicam","ampiroxicam","C065946",0,0,0,0,4]
["amyl acetate","amyl acetate","C005716",0,0,0,0,4]
["AN2728","AN2728","C543085",0,0,0,0,4]
["anthracene","anthracene","C034020",4,3,0,0,4]
["Arsanilic Acid","Arsanilic Acid","D001147",0,0,1,0,4]
["aurotioprol","aurotioprol","C013394",0,0,0,1,4]
["Baclofen","Baclofen","D001418",9,0,3,1,4]
["benoxinate","benoxinate","C005298",0,0,0,0,4]
["bepotastine besilate","bepotastine besilate","C511534",0,3,0,0,4]
["beta-1,3-glucan","beta-1,3-glucan","C033363",22,0,14,18,4]
["Betahistine","Betahistine","D001621",4,0,0,0,4]
["beta-Naphthoflavone","beta-Naphthoflavone","D019324",4,5,0,0,4]
["bis(aminopropyl)laurylamine","bis(aminopropyl)laurylamine","C109057",0,0,0,0,4]
["brequinar","brequinar","C046943",4,0,0,8,4]
["brilliant green","brilliant green","C006798",0,0,0,0,4]
["Bromazepam","Bromazepam","D001960",0,0,0,0,4]
["Bromisovalum","Bromisovalum","D001968",0,0,0,0,4]
["butylparaben","butylparaben","C038091",0,0,0,0,4]
["C.I. Solvent Orange 60","C.I. Solvent Orange 60","C401483",0,0,0,0,4]
["C.I. solvent red 3","C.I. solvent red 3","C049005",0,0,0,0,4]
["C30-38 olefin isopropyl maleate MA copolymer","C30-38 olefin isopropyl maleate MA copolymer","C560520",0,0,0,0,4]
["Cacodylic Acid","Cacodylic Acid","D002101",1,0,0,0,4]
["calocephalin","calocephalin","C586418",0,0,0,0,4]
["candidin","candidin","C010428",0,0,0,4,4]
["caprolactone","caprolactone","C121056",2,1,0,1,4]
["capryloyl salicylic acid","capryloyl salicylic acid","C000597299",0,0,0,0,4]
["capsiate","capsiate","C470213",0,3,0,3,4]
["carbamix","carbamix","C057051",0,0,0,0,4]
["Carmustine","Carmustine","D002330",4,0,2,11,4]
["carprofen","carprofen","C007005",4,0,0,0,4]
["Cefixime","Cefixime","D020682",14,0,0,0,4]
["cefodizime","cefodizime","C033356",5,0,0,8,4]
["Cefotetan","Cefotetan","D015313",7,0,0,0,4]
["Cefoxitin","Cefoxitin","D002440",12,0,0,0,4]
["Cellophane","Cellophane","D002476",1,0,0,0,4]
["Centella asiatica extract","Centella asiatica extract","C526146",0,3,0,0,4]
["Cephalothin","Cephalothin","D002512",21,0,3,0,4]
["Chlorthalidone","Chlorthalidone","D002752",6,0,0,0,4]
["chromotropic acid","chromotropic acid","C020996",0,0,0,0,4]
["chrysarobin","chrysarobin","C013883",0,5,0,0,4]
["cidofovir","cidofovir","C059262",1,15,4,15,4]
["cilastatin, imipenem drug combination","cilastatin, imipenem drug combination","C044650",0,0,0,0,4]
["cilostazol","cilostazol","C045645",2,0,3,9,4]
["citiolone","citiolone","C000486",0,0,0,0,4]
["Clenbuterol","Clenbuterol","D002976",7,0,3,3,4]
["Clomiphene","Clomiphene","D002996",20,0,0,0,4]
["Clonazepam","Clonazepam","D002998",7,0,0,0,4]
["cocobetaine","cocobetaine","C038020",0,0,0,0,4]
["coleon O","coleon O","C057776",0,0,0,0,4]
["copper phthalocyanine","copper phthalocyanine","C015445",2,0,0,0,4]
["costus absolute","costus absolute","C007139",0,0,0,0,4]
["Cotinine","Cotinine","D003367",3,0,2,0,4]
["Creosote","Creosote","D003407",2,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1732,B1732)","v":"crystal violet lactone"},"crystal violet lactone","C048923",0,0,0,0,4]
["cycloartenol","cycloartenol","C100089",0,0,0,3,4]
["DA 9601","DA 9601","C116959",0,0,0,0,4]
["dehydrocostus lactone","dehydrocostus lactone","C083030",0,6,0,0,4]
["delphinidin","delphinidin","C017185",2,11,0,3,4]
["Demecolcine","Demecolcine","D003703",10,3,0,3,4]
["deoxynivalenol","deoxynivalenol","C007262",13,3,16,68,4]
["Dermalive","Dermalive","C482306",0,0,0,0,4]
["dexamethasone 21-phosphate","dexamethasone 21-phosphate","C004180",2,0,0,0,4]
["Dextropropoxyphene","Dextropropoxyphene","D011431",8,0,0,0,4]
["diacetoxyscirpenol","diacetoxyscirpenol","C001809",0,0,0,10,4]
["Diazoxide","Diazoxide","D003981",19,1,3,3,4]
["dibutyl maleate","dibutyl maleate","C048074",0,0,0,0,4]
["dichlorodifluoromethane","dichlorodifluoromethane","C007782",0,0,0,0,4]
["didecyl methyl polyoxyethyl ammonium","didecyl methyl polyoxyethyl ammonium","C558284",0,0,0,0,4]
["didehydrofalcarinol","didehydrofalcarinol","C053263",0,0,0,0,4]
["diethanolamine","diethanolamine","C020283",1,0,0,0,4]
["diethyl fumarate","diethyl fumarate","C035088",0,0,0,0,4]
["diethylene glycol maleate","diethylene glycol maleate","C081553",0,0,0,0,4]
["diflorasone","diflorasone","C014477",0,0,0,0,4]
["diflucortolone valerate","diflucortolone valerate","C013486",0,0,0,0,4]
["difluprednate","difluprednate","C015808",0,0,0,0,4]
["dimethisoquin","dimethisoquin","C009146",0,0,0,0,4]
["Dimethylnitrosamine","Dimethylnitrosamine","D004128",15,0,1,16,4]
["dinitrobenzenesulfonic acid","dinitrobenzenesulfonic acid","C007488",0,0,6,0,4]
["disperse blue 85","disperse blue 85","C057777",0,0,0,0,4]
["Doublebase","Doublebase","C461579",0,0,0,0,4]
["Dragophos S","Dragophos S","C100378",0,0,0,0,4]
["Drinking Water","Drinking Water","D060766",1,3,1,4,4]
["Dronabinol","Dronabinol","D013759",62,7,20,101,4]
["Duloxetine Hydrochloride","Duloxetine Hydrochloride","D000068736",7,0,0,0,4]
["dyclonine","dyclonine","C100063",0,0,0,0,4]
["dyrene","dyrene","C004855",0,0,0,0,4]
["ebselen","ebselen","C042986",10,9,0,15,4]
["emulgade F","emulgade F","C051289",0,0,0,0,4]
["Endosulfan","Endosulfan","D004726",2,3,0,4,4]
["enilconazole","enilconazole","C017435",1,0,0,0,4]
["enterotoxin C, staphylococcal","enterotoxin C, staphylococcal","C034959",8,0,0,67,4]
["epinastine","epinastine","C053090",3,3,5,6,4]
["Esculin","Esculin","D004929",1,0,0,1,4]
["Esomeprazole","Esomeprazole","D064098",0,0,0,0,4]
["Ethacridine","Ethacridine","D004975",0,0,1,0,4]
["Ethacrynic Acid","Ethacrynic Acid","D004976",28,0,3,0,4]
["Ethchlorvynol","Ethchlorvynol","D004984",1,0,0,0,4]
["Ethiodized Oil","Ethiodized Oil","D004998",0,0,0,0,4]
["Ethosuximide","Ethosuximide","D005013",3,0,0,0,4]
["ethyl acetate","ethyl acetate","C007650",0,1,0,3,4]
["ethyl-2-bromo-4-methoxyphenylacetate","ethyl-2-bromo-4-methoxyphenylacetate","C076286",0,0,0,0,4]
["Ethylene Glycol","Ethylene Glycol","D019855",14,0,2,7,4]
["Ethylnitrosourea","Ethylnitrosourea","D005038",3,6,0,50,4]
["Eusol","Eusol","C024611",0,0,0,0,4]
["Eutanol G","Eutanol G","C037438",0,0,0,0,4]
["FD & C Yellow No. 6","FD & C Yellow No. 6","C005842",0,0,0,3,4]
["fenvalerate","fenvalerate","C017690",2,0,0,3,4]
["Flecainide","Flecainide","D005424",11,0,0,0,4]
["fluazinam","fluazinam","C075780",0,0,0,0,4]
["fluorescein isothiocyanate dextran","fluorescein isothiocyanate dextran","C015219",2,6,27,14,4]
["Flupenthixol","Flupenthixol","D005475",0,0,0,0,4]
["flutrimazole","flutrimazole","C076986",0,0,0,0,4]
["fosphenytoin","fosphenytoin","C043114",6,0,0,0,4]
["Fucose","Fucose","D005643",109,5,15,11,4]
["Fuller's Earth","Fuller's Earth","C001262",0,0,0,0,4]
["furaltadon","furaltadon","C007795",2,0,0,1,4]
["Galantamine","Galantamine","D005702",12,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1796,B1796)","v":"gallocatechol"},"gallocatechol","C057580",11,4,3,3,4]
["GDC-0973","GDC-0973","C574276",0,3,0,3,4]
["Glyburide","Glyburide","D005905",28,0,1,3,4]
["Grossman's sealer","Grossman's sealer","C045432",0,0,0,3,4]
["Grotan BK","Grotan BK","C011835",0,0,0,0,4]
["grotan OX","grotan OX","C039278",0,0,0,0,4]
["guar gum","guar gum","C007894",1,0,0,0,4]
["guggulu extract","guggulu extract","C018562",1,0,0,0,4]
["halofantrine","halofantrine","C023768",11,0,0,0,4]
["haloperidol decanoate","haloperidol decanoate","C033563",1,0,0,0,4]
["haloprogin","haloprogin","C100276",0,0,0,0,4]
["hesperidin methylchalcone","hesperidin methylchalcone","C033022",0,0,0,0,4]
["hexyl nicotinate","hexyl nicotinate","C049457",1,3,0,0,4]
["Hexylresorcinol","Hexylresorcinol","D006604",1,0,0,0,4]
["ibuprofen piconol","ibuprofen piconol","C052308",0,0,0,0,4]
["ichthammol","ichthammol","C089399",0,0,0,0,4]
["ingalipt","ingalipt","C012384",0,0,0,0,4]
["ingenol","ingenol","C008125",0,3,0,9,4]
["Inulin","Inulin","D007444",12,0,12,13,4]
["isoxicam","isoxicam","C013580",5,0,0,0,4]
["kakkon-to","kakkon-to","C090831",0,0,0,0,4]
["Karaya Gum","Karaya Gum","D007618",0,0,0,0,4]
["Kathon 930","Kathon 930","C080469",0,0,0,0,4]
["keishibukuryogan","keishibukuryogan","C054593",0,3,0,0,4]
["Ketanserin","Ketanserin","D007650",16,3,0,0,4]
["lacosamide","lacosamide","C403507",9,0,0,0,4]
["Lepromin","Lepromin","D007916",0,0,4,9,4]
["Leukotriene A4","Leukotriene A4","D017572",7,1,0,1,4]
["Leukotriene D4","Leukotriene D4","D017998",5,0,4,0,4]
["lewisite","lewisite","C035965",1,9,0,0,4]
["lilial","lilial","C038018",1,0,0,0,4]
["linalyl acetate","linalyl acetate","C074463",0,0,0,0,4]
["Linseed Oil","Linseed Oil","D008043",2,0,0,6,4]
["lupeol","lupeol","C010480",5,6,0,6,4]
["Lutein","Lutein","D014975",10,6,0,5,4]
["mafosfamide","mafosfamide","C048341",0,0,3,13,4]
["magnolol","magnolol","C005498",5,6,3,0,4]
["maleopimaric acid","maleopimaric acid","C027815",0,0,0,0,4]
["MDI 301","MDI 301","C488463",0,3,0,0,4]
["mebhydroline","mebhydroline","C005139",0,0,0,0,4]
["Medroxyprogesterone Acetate","Medroxyprogesterone Acetate","D017258",5,0,9,24,4]
["Megestrol","Megestrol","D008535",1,0,0,0,4]
["melamine formaldehyde","melamine formaldehyde","C504353",0,0,0,0,4]
["Memantine","Memantine","D008559",10,0,3,5,4]
["mequinol","mequinol","C009760",1,3,0,0,4]
["Mercaptoethanol","Mercaptoethanol","D008623",27,0,15,55,4]
["mercuric sulfate","mercuric sulfate","C028430",0,0,0,0,4]
["metanil yellow","metanil yellow","C005108",0,0,0,0,4]
["Metaproterenol","Metaproterenol","D009921",2,0,2,0,4]
["methacetin","methacetin","C035495",0,0,0,0,4]
["Methamphetamine","Methamphetamine","D008694",73,0,24,36,4]
["Methicillin","Methicillin","D008712",18,0,2,0,4]
["Methomyl","Methomyl","D008724",0,0,0,0,4]
["methyl gentisate","methyl gentisate","C117454",0,0,0,0,4]
["methyl heptine carbonate","methyl heptine carbonate","C023027",0,0,0,0,4]
["methyl isothiocyanate","methyl isothiocyanate","C005227",0,0,0,0,4]
["methyl vanillate","methyl vanillate","C000618837",0,3,0,0,4]
["Metipranolol","Metipranolol","D014290",1,0,0,0,4]
["mexenone","mexenone","C011031",0,0,0,0,4]
["miconidin","miconidin","C047212",0,0,0,0,4]
["midecamycin","midecamycin","C026483",3,0,0,0,4]
["Mifepristone","Mifepristone","D015735",26,0,0,51,4]
["Misoprostol","Misoprostol","D016595",2,0,0,3,4]
["mivacurium","mivacurium","C049430",1,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1860,B1860)","v":"mofebutazone"},"mofebutazone","C002374",2,0,0,0,4]
["monoperoxysulfate","monoperoxysulfate","C071517",0,0,0,0,4]
["Morantel","Morantel","D009015",3,0,0,0,4]
["N,N'-diphenyl-4-phenylenediamine","N,N'-diphenyl-4-phenylenediamine","C004845",1,0,0,0,4]
["N,N'-methylenebisacrylamide","N,N'-methylenebisacrylamide","C021221",0,0,0,0,4]
["NanoGel","NanoGel","C413692",1,3,19,6,4]
["Naphazoline","Naphazoline","D009278",1,0,0,0,4]
["n-butoxyethanol","n-butoxyethanol","C017096",3,0,0,0,4]
["neurotropin","neurotropin","C010491",0,0,0,16,4]
["n-hexadecane","n-hexadecane","C007932",3,0,0,0,4]
["Nialamide","Nialamide","D009526",0,0,0,0,4]
["Nicardipine","Nicardipine","D009529",9,0,1,6,4]
["N-isopropyl-p-phenylenediamine","N-isopropyl-p-phenylenediamine","C056153",0,0,0,0,4]
["N-Methyl-3,4-methylenedioxyamphetamine","N-Methyl-3,4-methylenedioxyamphetamine","D018817",54,0,3,10,4]
["Oleophytal","Oleophytal","C093226",0,0,0,0,4]
["Opium","Opium","D009892",3,0,0,7,4]
["Oxandrolone","Oxandrolone","D010074",1,0,0,0,4]
["oxatomide","oxatomide","C015408",0,0,0,3,4]
["oxiconazole","oxiconazole","C022155",0,0,0,3,4]
["P & S Liquid","P & S Liquid","C027222",0,0,0,0,4]
["padimate-O","padimate-O","C041981",0,3,0,0,4]
["PAMAM Starburst","PAMAM Starburst","C104700",39,18,7,7,4]
["Panscol Lotion","Panscol Lotion","C027221",0,0,0,0,4]
["paramethasone acetate","paramethasone acetate","C032128",0,0,0,0,4]
["Paraoxon","Paraoxon","D010261",17,0,0,3,4]
["PD168393","PD168393","C509204",0,0,0,0,4]
["pentaerythritol","pentaerythritol","C008783",0,0,1,3,4]
["peoniflorin","peoniflorin","C015423",2,10,10,8,4]
["Peracetic Acid","Peracetic Acid","D010463",2,0,0,3,4]
["phenylglycidyl ether","phenylglycidyl ether","C016050",0,3,0,0,4]
["Phenylmercuric Acetate","Phenylmercuric Acetate","D010662",4,0,0,0,4]
["Phloretin","Phloretin","D010693",4,6,7,8,4]
["phthalocyanine","phthalocyanine","C013647",8,3,4,6,4]
["Physostigmine","Physostigmine","D010830",9,0,0,4,4]
["phytosphingosine","phytosphingosine","C012491",3,15,0,4,4]
["picaridin","picaridin","C483506",1,0,0,0,4]
["picosulfate sodium","picosulfate sodium","C005701",0,0,0,0,4]
["pirenoxine","pirenoxine","C004580",1,0,0,0,4]
["pirinixic acid","pirinixic acid","C006253",5,6,0,0,4]
["piroxicam cinnamate","piroxicam cinnamate","C057291",0,0,0,0,4]
["pirprofen","pirprofen","C008924",5,0,0,0,4]
["plastochromanol 8","plastochromanol 8","C013649",1,6,0,6,4]
["poly(2,2,4-trimethyl-1,2-dihydroquinoline)","poly(2,2,4-trimethyl-1,2-dihydroquinoline)","C049004",0,0,0,0,4]
["polyaminopropylbiguanide","polyaminopropylbiguanide","C064420",0,3,0,0,4]
["polyethoxylated castor oil","polyethoxylated castor oil","C023040",0,0,1,0,4]
["polymeric 4,4'-diphenylmethane diisocyanate","polymeric 4,4'-diphenylmethane diisocyanate","C087867",1,0,0,0,4]
["propylene dichloride","propylene dichloride","C004765",0,0,0,0,4]
["protocatechuic acid","protocatechuic acid","C009091",0,3,1,0,4]
["proxymetacaine","proxymetacaine","C005717",0,0,0,0,4]
["pycnogenols","pycnogenols","C024070",4,8,0,3,4]
["pyrithione","pyrithione","C008704",0,0,0,0,4]
["Pyruvaldehyde","Pyruvaldehyde","D011765",35,7,1,7,4]
["Qingkailing","Qingkailing","C504928",0,0,0,0,4]
["Quetiapine Fumarate","Quetiapine Fumarate","D000069348",8,0,0,6,4]
["resazurin","resazurin","C005843",0,17,0,5,4]
["resiquimod","resiquimod","C402365",3,3,53,40,4]
["rhodioloside","rhodioloside","C009172",0,4,3,8,4]
["Riboflavin","Riboflavin","D012256",125,10,5,13,4]
["Rivaroxaban","Rivaroxaban","D000069552",1,0,0,0,4]
["rofetan GOT","rofetan GOT","C050207",0,0,0,0,4]
["Salactol","Salactol","C016094",0,0,0,0,4]
["Salazopyrine","Salazopyrine","C028423",0,0,0,0,4]
["Selenious Acid","Selenious Acid","D020887",4,0,0,7,4]
["Senna Extract","Senna Extract","D012676",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1924,B1924)","v":"sesamol"},"sesamol","C025583",5,0,0,0,4]
["Sisomicin","Sisomicin","D012853",4,0,0,0,4]
["Sodium Azide","Sodium Azide","D019810",6,3,2,0,4]
["Sodium Selenite","Sodium Selenite","D018038",12,8,4,31,4]
["Spermidine","Spermidine","D013095",36,13,1,10,4]
["Spermine","Spermine","D013096",55,3,4,31,4]
["sphingosine 1-phosphate","sphingosine 1-phosphate","C060506",73,41,55,133,4]
["SRI 63072","SRI 63072","C049820",0,0,0,0,4]
["Staurosporine","Staurosporine","D019311",43,31,5,39,4]
["Strychnine","Strychnine","D013331",11,0,0,2,4]
["Succimer","Succimer","D004113",12,3,0,3,4]
["sucrose monolaurate","sucrose monolaurate","C018152",1,0,0,0,4]
["Sulbactam","Sulbactam","D013407",6,0,0,0,4]
["sulforafan","sulforafan","C016766",8,7,6,0,4]
["sultamicillin","sultamicillin","C035444",0,0,0,0,4]
["Tactylon","Tactylon","C078515",0,0,0,0,4]
["taxane","taxane","C080625",3,0,0,3,4]
["Technetium Tc 99m Medronate","Technetium Tc 99m Medronate","D013669",7,0,0,0,4]
["telavancin","telavancin","C487637",4,0,0,0,4]
["tert-decanoic acid oxiranylmethyl ester","tert-decanoic acid oxiranylmethyl ester","C043703",0,0,0,0,4]
["tetramethylpyrazine","tetramethylpyrazine","C017953",10,3,0,3,4]
["tetraphenylporphine sulfonate","tetraphenylporphine sulfonate","C016136",13,0,0,0,4]
["Thebaine","Thebaine","D013797",3,0,0,0,4]
["Theobromine","Theobromine","D013805",5,0,0,4,4]
["thiolactic acid","thiolactic acid","C023884",0,0,0,0,4]
["thurfyl nicotinate","thurfyl nicotinate","C005813",0,0,0,0,4]
["tipifarnib","tipifarnib","C402769",3,0,0,0,4]
["tocotrienol, delta","tocotrienol, delta","C082097",0,0,0,3,4]
["tofacitinib","tofacitinib","C479163",6,4,9,83,4]
["tolciclate","tolciclate","C013305",0,0,0,0,4]
["Tolmetin","Tolmetin","D014046",31,0,0,3,4]
["Tolterodine Tartrate","Tolterodine Tartrate","D000068737",2,0,0,0,4]
["triamcinolone diacetate","triamcinolone diacetate","C030262",0,0,0,0,4]
["triazinate","triazinate","C012071",0,0,0,0,4]
["tribenoside","tribenoside","C100302",0,3,0,2,4]
["triforine","triforine","C012591",0,0,0,0,4]
["Trimebutine","Trimebutine","D014287",0,0,0,0,4]
["troclosene","troclosene","C011765",0,0,0,0,4]
["tulipalin B","tulipalin B","C048810",0,0,0,1,4]
["Unguentum Merck","Unguentum Merck","C052551",0,0,0,0,4]
["urea formaldehyde foam","urea formaldehyde foam","C028278",0,0,0,0,4]
["urethane acrylate","urethane acrylate","C050845",0,0,0,0,4]
["variclene","variclene","C040899",0,0,0,0,4]
["WEB 2086","WEB 2086","C052518",4,0,0,3,4]
["xylometazoline","xylometazoline","C009695",0,0,0,0,4]
["Yohimbine","Yohimbine","D015016",6,0,0,0,4]
["zinc dibenzyldithiocarbamate","zinc dibenzyldithiocarbamate","C005895",0,0,0,0,4]
["zonisamide","zonisamide","C022189",13,0,0,0,4]
["1,1-azobisformamide","1,1-azobisformamide","C004525",1,1,0,9,3]
["1,1-bis(4-chlorophenyl)chloromethane","1,1-bis(4-chlorophenyl)chloromethane","C026310",0,0,0,0,3]
["1,2-didecanoylglycerol","1,2-didecanoylglycerol","C044297",1,0,0,0,3]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060",43,0,1,0,3]
["1,2-hexanediol","1,2-hexanediol","C119102",0,0,0,0,3]
["1,4-bis(aminocyclohexyl)methane","1,4-bis(aminocyclohexyl)methane","C072821",0,0,0,0,3]
["11,15-dioxo-9-hydroxy-2,3,4,5-tetranorprostan-1,20-dioic acid","11,15-dioxo-9-hydroxy-2,3,4,5-tetranorprostan-1,20-dioic acid","C527346",0,0,0,0,3]
["11-dehydro-thromboxane B2","11-dehydro-thromboxane B2","C049235",0,0,0,0,3]
["11-octadecenoic acid","11-octadecenoic acid","C050413",0,0,0,0,3]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984",3,0,0,20,3]
["1-butyl-3-methylimidazolium chloride","1-butyl-3-methylimidazolium chloride","C502841",1,0,0,0,3]
["1-hydroxypyrene","1-hydroxypyrene","C033146",1,3,0,0,3]
["1-methyl-2-isopropylbenzene","1-methyl-2-isopropylbenzene","C046257",0,0,0,0,3]
["1-methyl-3-ethylimidazolium","1-methyl-3-ethylimidazolium","C048524",0,0,0,0,3]
["1-O-hexadecyl-2-N-methylcarbamol -sn-glycerol-3-phosphocholine","1-O-hexadecyl-2-N-methylcarbamol -sn-glycerol-3-phosphocholine","C083283",1,4,0,0,3]
["1-oleoyl-2-acetylglycerol","1-oleoyl-2-acetylglycerol","C038237",3,4,0,2,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1988,B1988)","v":"2,2,2-trichloroethanol"},"2,2,2-trichloroethanol","C005849",3,3,0,0,3]
["2,2'-dihydroxy-3,3'-dimethoxy-5,5'-diallylbiphenyl","2,2'-dihydroxy-3,3'-dimethoxy-5,5'-diallylbiphenyl","C490159",0,0,0,0,3]
["2,3,7,8-tetrachlorodibenzofuran","2,3,7,8-tetrachlorodibenzofuran","C014211",0,4,0,0,3]
["2,4-Dinitrophenol","2,4-Dinitrophenol","D019297",10,0,1,4,3]
["2,6-dithiopurine","2,6-dithiopurine","C070898",0,0,0,0,3]
["2-Aminopurine","2-Aminopurine","D015075",16,0,0,7,3]
["2-diethylaminoethanol","2-diethylaminoethanol","C007369",1,0,0,4,3]
["3,4,5-trichloropyridazine","3,4,5-trichloropyridazine","C057049",0,0,0,0,3]
["3beta,6beta,16beta-trihidroxilup-20(29)-ene","3beta,6beta,16beta-trihidroxilup-20(29)-ene","C510987",0,3,0,0,3]
["3-Mercaptopropionic Acid","3-Mercaptopropionic Acid","D015097",6,0,0,0,3]
["4,5'-diallyl-1,2'-dihydroxy-2,3'-dimethoxyphenyl ether","4,5'-diallyl-1,2'-dihydroxy-2,3'-dimethoxyphenyl ether","C490160",0,0,0,0,3]
["4-chlorophenol","4-chlorophenol","C029107",0,0,3,1,3]
["4-cresol","4-cresol","C032538",4,0,0,0,3]
["4-methylcyclohexanemethanol","4-methylcyclohexanemethanol","C000607184",0,0,0,0,3]
["6-formylindolo(3,2-b)carbazole","6-formylindolo(3,2-b)carbazole","C111855",0,10,0,5,3]
["Acarbose","Acarbose","D020909",7,0,0,1,3]
["Aclarubicin","Aclarubicin","D015250",1,0,1,4,3]
["allyl glycidyl ether","allyl glycidyl ether","C054361",1,0,0,0,3]
["arsenic trioxide","arsenic trioxide","C006632",32,16,4,56,3]
["B 220","B 220","C060183",0,0,0,0,3]
["Biafine","Biafine","C423724",0,0,0,0,3]
["bixin","bixin","C004588",5,3,0,0,3]
["cabozantinib","cabozantinib","C558660",3,0,0,3,3]
["Carubicin","Carubicin","D002360",2,0,8,16,3]
["cefozopran","cefozopran","C070918",5,0,0,0,3]
["cinnamic acid","cinnamic acid","C029010",9,0,0,0,3]
["CP 96345","CP 96345","C066892",0,0,0,4,3]
["cylindrospermopsin","cylindrospermopsin","C089595",1,0,0,3,3]
["Diosmin","Diosmin","D004145",0,0,0,0,3]
["Escin","Escin","D004928",2,0,0,0,3]
["ethyl acrylate","ethyl acrylate","C040833",2,3,0,0,3]
["Eucalyptus terpene oil","Eucalyptus terpene oil","C511306",0,0,0,0,3]
["fluvastatin","fluvastatin","C065180",10,7,0,18,3]
["glimepiride","glimepiride","C057619",6,0,0,0,3]
["HDM vaccine","HDM vaccine","C066017",0,0,0,0,3]
["INCB018424","INCB018424","C540383",1,4,13,15,3]
["indacrinone","indacrinone","C013352",2,0,0,0,3]
["Lincomycin","Lincomycin","D008034",9,0,5,0,3]
["mannosylerythritol lipid","mannosylerythritol lipid","C439671",9,0,0,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2180,B2180)","v":"maxacalcitol"},"maxacalcitol","C051883",5,14,0,1,3]
["metribuzin","metribuzin","C009235",0,0,0,0,3]
["N(1)-methylnicotinamide","N(1)-methylnicotinamide","C024058",2,0,0,6,3]
["Naloxone","Naloxone","D009270",28,0,0,29,3]
["neutral lipid, phosphatidylcholine, phosphatidylethanolamine drug combination","neutral lipid, phosphatidylcholine, phosphatidylethanolamine drug combination","C046637",0,0,0,8,3]
["nonivamide","nonivamide","C040937",0,0,0,0,3]
["Octoxynol","Octoxynol","D017830",13,6,1,7,3]
["parthenin","parthenin","C022097",0,0,0,0,3]
["Perlite","Perlite","C003076",0,0,0,0,3]
["Phenolsulfonphthalein","Phenolsulfonphthalein","D010637",13,0,0,0,3]
["polychlorodibenzofuran","polychlorodibenzofuran","C016068",0,0,0,3,3]
["polyribose phosphate","polyribose phosphate","C003191",0,0,0,1,3]
["Putrescine","Putrescine","D011700",25,4,3,2,3]
["regorafenib","regorafenib","C559147",3,0,0,3,3]
["Roflumilast","Roflumilast","C424423",1,0,4,12,3]
["salmonella toxin","salmonella toxin","C027952",1,0,0,2,3]
["sesamin","sesamin","C054125",1,0,0,0,3]
["spironolactone, althiazide drug combination","spironolactone, althiazide drug combination","C026063",0,0,0,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2308,B2308)","v":"tandospirone"},"tandospirone","C055267",0,0,0,0,3]
["tetrachlorophthalic anhydride","tetrachlorophthalic anhydride","C009409",0,0,0,0,3]
["tolfenamic acid","tolfenamic acid","C009500",8,0,0,0,3]
["turmeric extract","turmeric extract","C012596",2,0,0,6,3]
["verteporfin","verteporfin","C098350",3,0,0,5,3]
["(polyethylene-acrylic acid) copolymer","(polyethylene-acrylic acid) copolymer","C083316",0,0,0,0,2]
["1,2-dichloro-4-nitrobenzene","1,2-dichloro-4-nitrobenzene","C028328",0,0,0,0,2]
["1,2-epoxy-3-(p-nitrophenoxy)propane","1,2-epoxy-3-(p-nitrophenoxy)propane","C007606",0,0,0,0,2]
["1,4-bis(chloromethyl)benzene","1,4-bis(chloromethyl)benzene","C021150",0,0,0,0,2]
["12-hydroxy stearic acid","12-hydroxy stearic acid","C539357",0,0,0,0,2]
["1-Methyl-3-isobutylxanthine","1-Methyl-3-isobutylxanthine","D015056",6,9,0,6,2]
["2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate","2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate","C487980",0,0,0,0,2]
["2,3-dichloro-4-bromotetrahydrothiophene-1,1-dioxide","2,3-dichloro-4-bromotetrahydrothiophene-1,1-dioxide","C027995",0,0,0,0,2]
["2,6-dichlorobenzoyl chloride","2,6-dichlorobenzoyl chloride","C055870",0,0,0,0,2]
["2-amino-2-methyl-1-propanol","2-amino-2-methyl-1-propanol","C006551",0,0,0,0,2]
["2-cresol","2-cresol","C034047",0,0,0,0,2]
["2-phenylethyl(dibutyl)acetic acid ethyl ester","2-phenylethyl(dibutyl)acetic acid ethyl ester","C103876",0,0,0,0,2]
["2-phenyltetralone tosylhydrazone","2-phenyltetralone tosylhydrazone","C049520",0,0,0,0,2]
["3',4'-dihydroxyflavone","3',4'-dihydroxyflavone","C028288",0,0,0,0,2]
["4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid","4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid","C038864",1,1,0,0,2]
["4-(2,4,6-trimethyl-3-cyclohexen-1-yl)-3-buten-2-one","4-(2,4,6-trimethyl-3-cyclohexen-1-yl)-3-buten-2-one","C526431",0,0,0,0,2]
["4,4'-dihydroxy-3,5-di-(hydroxymethyl)diphenylmethane","4,4'-dihydroxy-3,5-di-(hydroxymethyl)diphenylmethane","C049218",0,0,0,0,2]
["4-bromomethyl-6,8-dimethyl-2(1H)-quinolone","4-bromomethyl-6,8-dimethyl-2(1H)-quinolone","C031176",0,0,0,0,2]
["4-chloro-alpha,alpha,alpha-trifluoro-3-nitrotoluene","4-chloro-alpha,alpha,alpha-trifluoro-3-nitrotoluene","C027565",0,0,0,0,2]
["4-diazo-N,N-diethylaniline","4-diazo-N,N-diethylaniline","C026732",0,0,0,0,2]
["4-nitrophenyl-N-(2-chloroethyl)-N-nitrosocarbamate","4-nitrophenyl-N-(2-chloroethyl)-N-nitrosocarbamate","C064429",0,0,0,0,2]
["5-(2-formyl-3-hydroxyphenoxy)pentanoic acid","5-(2-formyl-3-hydroxyphenoxy)pentanoic acid","C039599",1,0,0,0,2]
["6-(4-(aminomethyl)-2-chlorophenoxyl)benzo(c)(1,2)oxaborol-1(3H)-ol","6-(4-(aminomethyl)-2-chlorophenoxyl)benzo(c)(1,2)oxaborol-1(3H)-ol","C579257",1,0,0,0,2]
["8,9-dihydro-8,9-dihydroxybenzanthracene 10,11-oxide","8,9-dihydro-8,9-dihydroxybenzanthracene 10,11-oxide","C026622",0,0,0,0,2]
["8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid","8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid","C038243",0,0,0,0,2]
["acamprosate","acamprosate","C043877",4,0,0,0,2]
["acetophenoneazine","acetophenoneazine","C532576",0,0,0,0,2]
["aclidinium bromide","aclidinium bromide","C542859",0,0,0,0,2]
["allergovit","allergovit","C099681",0,0,0,0,2]
["alpha-ionone","alpha-ionone","C011879",1,0,0,0,2]
["Alprazolam","Alprazolam","D000525",4,0,0,15,2]
["Alutard SQ allergen","Alutard SQ allergen","C521342",0,0,0,0,2]
["angelicin","angelicin","C011659",2,0,0,0,2]
["anthrarobin","anthrarobin","C032186",0,0,0,0,2]
["Arecoline","Arecoline","D001115",5,32,0,4,2]
["arjunolic acid","arjunolic acid","C061640",0,0,0,0,2]
["Azacosterol","Azacosterol","D001373",0,0,0,0,2]
["bendazac","bendazac","C000123",3,0,0,0,2]
["Benzbromarone","Benzbromarone","D001553",5,0,0,0,2]
["benzothiazole","benzothiazole","C005465",14,0,0,3,2]
["beta-ionone","beta-ionone","C008157",5,0,0,0,2]
["binedaline","binedaline","C044680",3,0,0,0,2]
["bis-A-TDA","bis-A-TDA","C037570",0,0,0,0,2]
["bonafton","bonafton","C011180",0,0,0,0,2]
["bromosuccinic acid","bromosuccinic acid","C033594",0,0,0,0,2]
["C.I. Acid Red 85","C.I. Acid Red 85","C034148",0,0,0,0,2]
["calcium bromide","calcium bromide","C113019",0,0,0,0,2]
["Canrenone","Canrenone","D002192",6,0,0,0,2]
["Carbarson","Carbarson","C033007",0,0,0,0,2]
["caryophyllene","caryophyllene","C024714",0,0,0,3,2]
["ceramide 3","ceramide 3","C018480",0,0,0,0,2]
["chlorcyclizine","chlorcyclizine","C084597",0,0,0,0,2]
["chloroaluminum tetrasulfophthalocyanine","chloroaluminum tetrasulfophthalocyanine","C052736",0,0,0,0,2]
["chlorous acid","chlorous acid","C063160",0,0,0,0,2]
["Cholic Acid","Cholic Acid","D019826",11,0,0,3,2]
["cimaterol","cimaterol","C047411",0,0,0,0,2]
["cis-3-hexenyl cinnamate","cis-3-hexenyl cinnamate","C526341",0,0,0,0,2]
["Cocospropylenediamine-guanidinium diacetate","Cocospropylenediamine-guanidinium diacetate","C464483",0,0,0,0,2]
["cryptotanshinone","cryptotanshinone","C037886",3,0,0,4,2]
["Cyclizine","Cyclizine","D003501",4,0,0,0,2]
["Cytochalasin B","Cytochalasin B","D003571",43,0,3,36,2]
["delta(3)-carene","delta(3)-carene","C507855",0,0,0,0,2]
["diacetylmonoxime","diacetylmonoxime","C004717",2,0,0,3,2]
["dichlorobenzyl alcohol","dichlorobenzyl alcohol","C008396",0,0,0,0,2]
["dihydroavenanthramide D","dihydroavenanthramide D","C532345",0,0,0,0,2]
["dihydrocodeine","dihydrocodeine","C014481",0,0,0,0,2]
["dimethylpropiothetin","dimethylpropiothetin","C068078",1,0,0,0,2]
["disodium hexachloroplatinate","disodium hexachloroplatinate","C038762",0,0,3,0,2]
["disperse yellow 27","disperse yellow 27","C117113",0,0,0,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2820,B2820)","v":"earex"},"earex","C047581",0,0,0,0,2]
["ensulizole","ensulizole","C499767",0,0,0,0,2]
["epacadostat","epacadostat","C000613752",1,0,3,0,2]
["Erythritol","Erythritol","D004896",4,0,0,6,2]
["ethoxymethylenemalononitrile","ethoxymethylenemalononitrile","C112505",0,0,0,0,2]
["ethyl bromoacetate","ethyl bromoacetate","C010144",0,0,0,0,2]
["ethylhexyl methoxycinnamate","ethylhexyl methoxycinnamate","C516303",0,0,0,0,2]
["Factu","Factu","C012315",0,0,0,0,2]
["fenclofenac","fenclofenac","C012970",1,0,0,3,2]
["ferrous chloride","ferrous chloride","C029451",0,3,0,0,2]
["fluorophosphate","fluorophosphate","C012980",6,0,0,0,2]
["Formoterol Fumarate","Formoterol Fumarate","D000068759",0,0,1,7,2]
["furfuryl alcohol","furfuryl alcohol","C012986",0,0,0,0,2]
["gamma-oryzanol","gamma-oryzanol","C013172",1,0,0,0,2]
["Gestodene","Gestodene","C033273",9,0,0,0,2]
["glutaric anhydride","glutaric anhydride","C079643",0,0,0,0,2]
["glycidyl 1-naphthyl ether","glycidyl 1-naphthyl ether","C082853",0,0,0,0,2]
["GW870086X","GW870086X","C581038",0,0,0,0,2]
["hexadecyl isononanoate","hexadecyl isononanoate","C484944",0,0,0,0,2]
["hexylene glycol","hexylene glycol","C011480",3,0,0,0,2]
["hydrochlorothiazide-triamterene","hydrochlorothiazide-triamterene","C020743",0,0,0,0,2]
["Hypalon","Hypalon","C040004",0,0,0,0,2]
["Indoramin","Indoramin","D007217",1,0,0,0,2]
["irgarol 1051","irgarol 1051","C103341",0,0,0,0,2]
["isoeugenol benzyl ether","isoeugenol benzyl ether","C062158",0,0,0,0,2]
["Jessner's solution","Jessner's solution","C061170",0,0,0,0,2]
["Kamillosan","Kamillosan","C056251",0,0,0,0,2]
["lacri-lube","lacri-lube","C014633",0,0,0,0,2]
["Lentinan","Lentinan","D007912",2,0,5,47,2]
["Linagliptin","Linagliptin","D000069476",3,3,0,0,2]
["Lowicryl 4KM resin","Lowicryl 4KM resin","C037883",0,0,0,0,2]
["malachite","malachite","C520661",0,0,0,0,2]
["masonin","masonin","C057586",0,0,0,0,2]
["menthone","menthone","C019466",1,3,0,0,2]
["mesulfen","mesulfen","C011911",0,0,0,0,2]
["Methotrimeprazine","Methotrimeprazine","D008728",0,0,0,3,2]
["methyl ethyl ketone peroxide","methyl ethyl ketone peroxide","C011007",0,0,0,0,2]
["methyl octanesulfonate","methyl octanesulfonate","C073310",0,0,0,0,2]
["metsulfuron methyl","metsulfuron methyl","C050296",0,0,0,0,2]
["MK 2206","MK 2206","C548887",1,0,0,0,2]
["monooctanoin","monooctanoin","C025343",0,0,0,0,2]
["myristyl lactate","myristyl lactate","C067638",0,0,0,0,2]
["N,N-bis(2-hydroxyethyl)-4-toluidine","N,N-bis(2-hydroxyethyl)-4-toluidine","C038496",0,0,0,0,2]
["N,N-bis(3-aminopropyl)dodecylamine","N,N-bis(3-aminopropyl)dodecylamine","C433886",0,0,0,0,2]
["naltrindole","naltrindole","C055382",3,0,1,10,2]
["Nicergoline","Nicergoline","D009530",1,0,0,0,2]
["nichrome","nichrome","C066018",0,0,0,0,2]
["nonanoyl amido caproylacid oxybenzenesulfonate","nonanoyl amido caproylacid oxybenzenesulfonate","C465962",0,0,0,0,2]
["Novo-Helisen Depot","Novo-Helisen Depot","C014135",0,0,0,0,2]
["n-tetradecane","n-tetradecane","C024713",1,0,0,0,2]
["oleth-5","oleth-5","C109605",0,0,0,0,2]
["oryzemate","oryzemate","C099063",0,0,0,0,2]
["oxycodone-acetaminophen","oxycodone-acetaminophen","C514822",0,0,0,0,2]
["paraffin oils","paraffin oils","C015418",0,0,0,0,2]
["Pentavac","Pentavac","C426945",0,0,0,0,2]
["PF-06297470","PF-06297470","C000609184",0,0,0,0,2]
["phenylacetaldehyde","phenylacetaldehyde","C013192",0,0,0,0,2]
["Phorbol 12,13-Dibutyrate","Phorbol 12,13-Dibutyrate","D015240",27,0,0,63,2]
["Picibanil","Picibanil","D010844",3,1,75,104,2]
["pirarubicin","pirarubicin","C027260",1,0,0,0,2]
["platycodin D","platycodin D","C108953",0,3,0,1,2]
["poly(phthalic anhydride-co-trimellitic anhydride-co-glycols)","poly(phthalic anhydride-co-trimellitic anhydride-co-glycols)","C465963",0,0,0,0,2]
["polyethylene glycol-7 monooleate","polyethylene glycol-7 monooleate","C000602201",0,0,0,0,2]
["polypropylene glycol","polypropylene glycol","C012504",0,0,0,0,2]
["potassium perchlorate","potassium perchlorate","C009006",0,0,0,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3268,B3268)","v":"Procarbazine"},"Procarbazine","D011344",2,0,0,2,2]
["propylene glycol monoacrylate","propylene glycol monoacrylate","C030214",0,0,0,0,2]
["pyrazinobutazone","pyrazinobutazone","C100279",0,0,0,0,2]
["Pyridoxal Phosphate","Pyridoxal Phosphate","D011732",291,1,5,5,2]
["raltitrexed","raltitrexed","C068874",7,0,0,0,2]
["rilmenidine","rilmenidine","C032302",2,0,0,0,2]
["S-2 (2-aminoethylamino)ethylphenylsulfide","S-2 (2-aminoethylamino)ethylphenylsulfide","C438646",0,0,0,0,2]
["sanyrene","sanyrene","C110597",0,0,0,0,2]
["Selegiline","Selegiline","D012642",13,0,0,4,2]
["sibutramine","sibutramine","C058254",2,0,0,0,2]
["sodium crompromate","sodium crompromate","C047659",0,0,0,0,2]
["sodium tungstate(VI)","sodium tungstate(VI)","C025399",0,0,0,3,2]
["Sotalol","Sotalol","D013015",5,0,0,0,2]
["stearoyl-2-lactylic acid","stearoyl-2-lactylic acid","C031568",0,0,0,0,2]
["sudan III","sudan III","C033006",1,0,0,0,2]
["sulfuretin","sulfuretin","C054989",1,0,0,0,2]
["Synthaderm","Synthaderm","C040003",0,0,0,0,2]
["tectol","tectol","C053744",0,0,0,0,2]
["terpinyl acetate","terpinyl acetate","C019564",0,0,0,0,2]
["tetrachloronitrobenzene","tetrachloronitrobenzene","C019567",0,0,0,0,2]
["Thiamine Pyrophosphate","Thiamine Pyrophosphate","D013835",55,0,1,0,2]
["tibolone","tibolone","C027385",1,0,0,0,2]
["tipepidine","tipepidine","C028458",0,0,0,0,2]
["Trapidil","Trapidil","D014192",3,0,0,3,2]
["trifluoroacetic anhydride","trifluoroacetic anhydride","C017958",0,0,0,0,2]
["Triflupromazine","Triflupromazine","D014273",5,0,0,0,2]
["Triparanol","Triparanol","D014308",1,0,0,0,2]
["uromune","uromune","C581747",0,0,1,0,2]
["Ursodeoxycholic Acid","Ursodeoxycholic Acid","D014580",19,0,3,11,2]
["vitamin A2","vitamin A2","C024366",1,7,0,0,2]
["Zearalenone","Zearalenone","D015025",10,4,0,8,2]
["zileuton","zileuton","C063449",5,0,0,4,2]
["(E)-2-isopropyl-5-methylcyclohexyl octadec-9-enoate","(E)-2-isopropyl-5-methylcyclohexyl octadec-9-enoate","C559968",0,0,0,0,1]
["1-(1-glycero)dodeca-1,3,5,7,9-pentaene","1-(1-glycero)dodeca-1,3,5,7,9-pentaene","C037357",0,0,0,0,1]
["1-(2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl)-3-(2-methylquinolin-4-yl)urea","1-(2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl)-3-(2-methylquinolin-4-yl)urea","C493249",0,0,0,0,1]
["1-(4-fluorobenzoyl)-3-(((6-methoxy-2-naphthyl)oxy)methyl)azetidine-3-carboxylic acid","1-(4-fluorobenzoyl)-3-(((6-methoxy-2-naphthyl)oxy)methyl)azetidine-3-carboxylic acid","C570688",0,0,0,0,1]
["1,1-dimethyl-2-phenylethyl formate","1,1-dimethyl-2-phenylethyl formate","C577714",0,0,0,0,1]
["1,25-dihydroxyergocalciferol","1,25-dihydroxyergocalciferol","C003564",3,1,3,0,1]
["1,2-hexanoylphosphatidylcholine","1,2-hexanoylphosphatidylcholine","C032166",3,0,0,0,1]
["1,3-propanediol","1,3-propanediol","C041787",2,0,0,0,1]
["1,4-naphthoquinone","1,4-naphthoquinone","C035342",7,3,0,0,1]
["10-hydroxy-12-octadecenoic acid","10-hydroxy-12-octadecenoic acid","C040430",0,0,0,0,1]
["11-deoxyprostaglandin E2-1-alcohol","11-deoxyprostaglandin E2-1-alcohol","C067521",0,0,0,0,1]
["12-hydroxy-5,8,14-eicosatrienoic acid","12-hydroxy-5,8,14-eicosatrienoic acid","C067514",0,0,0,0,1]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240",24,12,7,31,1]
["16-(4-fluorophenoxy)-3-oxa-5,6,15-trihydroxy-7,9,13-hexadecatrien-11-ynoic acid","16-(4-fluorophenoxy)-3-oxa-5,6,15-trihydroxy-7,9,13-hexadecatrien-11-ynoic acid","C485115",0,0,0,0,1]
["1-decyl methyl sulfoxide","1-decyl methyl sulfoxide","C054274",0,0,0,0,1]
["1-O-glucopyranosyl-2-(2'-hydroxyeicosanoylamino)-4,11-octadecadiene-1,3-diol","1-O-glucopyranosyl-2-(2'-hydroxyeicosanoylamino)-4,11-octadecadiene-1,3-diol","C524115",0,0,0,0,1]
["1-spiro(4.5)dec-7-en-7-yl-4-pent-1-one","1-spiro(4.5)dec-7-en-7-yl-4-pent-1-one","C000589153",0,0,0,0,1]
["2-(3,7-dimethyl-2,6-octadienyl)cyclopentanone","2-(3,7-dimethyl-2,6-octadienyl)cyclopentanone","C578101",0,0,0,0,1]
["2-(5-(2,4,6-trimethoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)naphthalen-1-ol","2-(5-(2,4,6-trimethoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)naphthalen-1-ol","C000605838",0,3,0,0,1]
["2-(p-tolyloxy)ethyl acetate","2-(p-tolyloxy)ethyl acetate","C577822",0,0,0,0,1]
["2,2'-thiodiethanol","2,2'-thiodiethanol","C047519",1,0,0,0,1]
["2,3,7,8-tetrabromodibenzo-4-dioxin","2,3,7,8-tetrabromodibenzo-4-dioxin","C066841",0,0,0,1,1]
["2,4,5-Trichlorophenoxyacetic Acid","2,4,5-Trichlorophenoxyacetic Acid","D015085",9,0,0,3,1]
["2,5-hexanedione","2,5-hexanedione","C011269",7,0,0,3,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3652,B3652)","v":"2,6-dimethoxy-N-phenylbenzamide"},"2,6-dimethoxy-N-phenylbenzamide","C482118",0,0,0,0,1]
["28-deacetylbelamcandal","28-deacetylbelamcandal","C118094",1,0,0,0,1]
["2-allyloxyethanol","2-allyloxyethanol","C094268",0,0,0,0,1]
["2-chloroethyl-3-chloropropylsulfide","2-chloroethyl-3-chloropropylsulfide","C055920",0,0,0,0,1]
["2-heptylcyclopentanone","2-heptylcyclopentanone","C578023",0,0,0,0,1]
["2-hydroxy-2-phenylethyl acetate","2-hydroxy-2-phenylethyl acetate","C577733",0,0,0,0,1]
["2-methyl-4-phenylpentanol","2-methyl-4-phenylpentanol","C577663",0,0,0,0,1]
["2-nitronaphthalene","2-nitronaphthalene","C048317",0,0,0,0,1]
["2-phenoxyethyl propionate","2-phenoxyethyl propionate","C577823",0,0,0,0,1]
["3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid","3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid","C477898",0,0,0,0,1]
["3,4,3',4'-tetrachloroazoxybenzene","3,4,3',4'-tetrachloroazoxybenzene","C013280",0,0,0,0,1]
["3,4-didehydroretinoic acid","3,4-didehydroretinoic acid","C064742",0,7,0,0,1]
["3,7-dimethyl-1-propargylxanthine","3,7-dimethyl-1-propargylxanthine","C057837",1,0,0,1,1]
["3-carbethoxypyranocoumarin","3-carbethoxypyranocoumarin","C046031",0,0,0,0,1]
["3'-keto rhododendrin","3'-keto rhododendrin","C580978",0,0,0,0,1]
["3-nitrotoluene","3-nitrotoluene","C029956",0,0,0,0,1]
["3'-O-methylepicatechin","3'-O-methylepicatechin","C424450",0,0,0,0,1]
["3-phenylpropyl isobutyrate","3-phenylpropyl isobutyrate","C571595",0,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3780,B3780)","v":"4,4',5'-trimethylazapsoralen"},"4,4',5'-trimethylazapsoralen","C067366",0,0,4,0,1]
["4,4'-bipyridyl","4,4'-bipyridyl","C034306",0,6,0,0,1]
["4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid","4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid","D012856",24,0,0,7,1]
["4'-galactooligosaccharide","4'-galactooligosaccharide","C072242",1,0,0,0,1]
["4-hydroxypanduratin A","4-hydroxypanduratin A","C525185",0,0,0,0,1]
["4-methylbenzyl acetate","4-methylbenzyl acetate","C577821",0,0,0,0,1]
["4-phenylpiracetam","4-phenylpiracetam","C037917",0,0,0,0,1]
["4-tolyl isocyanate","4-tolyl isocyanate","C025637",0,0,0,0,1]
["5,12,20-trihydroxy-6,8,10,14-eicosatetraenoic acid","5,12,20-trihydroxy-6,8,10,14-eicosatetraenoic acid","C031571",0,0,0,0,1]
["5-adamantan-1-yl-N-(2,4-dihydroxybenzyl)-2,4-dimethoxybenzamide","5-adamantan-1-yl-N-(2,4-dihydroxybenzyl)-2,4-dimethoxybenzamide","C000592311",0,0,0,0,1]
["5-amino levulinic acid","5-amino levulinic acid","C000614854",0,0,0,0,1]
["5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid","5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid","C499823",3,0,7,14,1]
["6-(4-(5-fluoro-2-trifluoromethylbenzoyl)piperazin-1-yl)pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide","6-(4-(5-fluoro-2-trifluoromethylbenzoyl)piperazin-1-yl)pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide","C583719",0,0,0,0,1]
["6-cyclohexyl-N-hydroxy-3-(3-(((methylsulfonyl)amino)methyl)-1,2,4-oxadiazol-5-yl)hexanamide","6-cyclohexyl-N-hydroxy-3-(3-(((methylsulfonyl)amino)methyl)-1,2,4-oxadiazol-5-yl)hexanamide","C523406",0,0,0,0,1]
["6-hydroxybenzo(b)thiophene-2-sulfonamide acetate ester","6-hydroxybenzo(b)thiophene-2-sulfonamide acetate ester","C061835",0,0,0,0,1]
["6-paradol","6-paradol","C421614",0,0,0,0,1]
["7-bromo-2-(4-hydroxyanilino)tropone","7-bromo-2-(4-hydroxyanilino)tropone","C541643",0,0,0,0,1]
["9-((cis-1,2-bis(hydroxymethyl)cycloprop-1-yl)methyl)guanine","9-((cis-1,2-bis(hydroxymethyl)cycloprop-1-yl)methyl)guanine","C111645",0,0,0,0,1]
["Abscisic Acid","Abscisic Acid","D000040",192,5,0,1,1]
["acrylic acid-allyl pentaerythritol copolymer","acrylic acid-allyl pentaerythritol copolymer","C044876",0,0,0,0,1]
["afimoxifene","afimoxifene","C016601",32,10,2,2,1]
["aliskiren","aliskiren","C446481",15,0,0,0,1]
["allergen Den n 1","allergen Den n 1","C432046",0,0,0,0,1]
["aloemannan","aloemannan","C120643",0,0,0,0,1]
["alpha-irone","alpha-irone","C008168",0,0,0,0,1]
["alternariol","alternariol","C005197",0,0,0,0,1]
["ametantrone","ametantrone","C020182",1,0,0,0,1]
["Amphetamine","Amphetamine","D000661",50,1,3,9,1]
["ankaferd blood stopper","ankaferd blood stopper","C539751",0,0,0,0,1]
["Antimony Sodium Gluconate","Antimony Sodium Gluconate","D000967",0,0,4,16,1]
["AR 12456","AR 12456","C046930",0,0,0,0,1]
["aristolochic acid I","aristolochic acid I","C000228",6,0,0,1,1]
["astragalin","astragalin","C001579",0,0,0,3,1]
["azaspirane","azaspirane","C099015",0,0,0,0,1]
["balofloxacin","balofloxacin","C077155",1,0,0,0,1]
["barium nitrate","barium nitrate","C023545",0,0,0,0,1]
["belotero balance","belotero balance","C584568",0,0,0,1,1]
["benzo(b)thiophene-2-carboxylic acid","benzo(b)thiophene-2-carboxylic acid","C026163",0,0,0,0,1]
["benzyl 2-hydroxypropionate","benzyl 2-hydroxypropionate","C577691",0,0,0,0,1]
["bepafant","bepafant","C063964",0,0,1,1,1]
["beta-glycerophosphoric acid","beta-glycerophosphoric acid","C031463",0,0,0,0,1]
["betulonic acid","betulonic acid","C118308",0,0,0,0,1]
["bimoclomol","bimoclomol","C108730",1,0,0,0,1]
["bis(4-oxyphenyl)sulfide","bis(4-oxyphenyl)sulfide","C069693",0,0,0,0,1]
["blastmycetin F","blastmycetin F","C087535",0,0,0,0,1]
["boron nitride","boron nitride","C017282",1,0,0,0,1]
["butachlor","butachlor","C054409",1,0,0,0,1]
["Calcium Pyrophosphate","Calcium Pyrophosphate","D002131",2,0,0,0,1]
["calix(4)arene","calix(4)arene","C121325",15,0,0,0,1]
["cannabigerol","cannabigerol","C037036",1,3,0,0,1]
["carbopol 934P","carbopol 934P","C453622",0,0,0,0,1]
["carboxymethylscleroglucan","carboxymethylscleroglucan","C526264",0,0,0,0,1]
["CFM 1571","CFM 1571","C419404",0,0,0,0,1]
["Chlordecone","Chlordecone","D007631",7,0,0,3,1]
["chloropicrin","chloropicrin","C100187",0,0,0,0,1]
["ciglitazone","ciglitazone","C039671",5,3,4,18,1]
["Cisapride","Cisapride","D020117",5,0,0,0,1]
["citraconic anhydride","citraconic anhydride","C035824",1,0,4,0,1]
["COB223","COB223","C000604218",0,0,0,0,1]
["copper(II) aspirinate","copper(II) aspirinate","C507908",0,3,0,0,1]
["corilagin","corilagin","C049096",1,3,0,0,1]
["CT-102 activated platelet supernatant","CT-102 activated platelet supernatant","C078881",0,0,0,0,1]
["cyanuric acid","cyanuric acid","C004632",4,0,0,0,1]
["cyclohexadec-8-en-1-one","cyclohexadec-8-en-1-one","C571566",0,0,0,0,1]
["cyclotene","cyclotene","C028407",0,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4228,B4228)","v":"decabromobiphenyl ether"},"decabromobiphenyl ether","C010902",3,0,0,6,1]
["decyl-6-(2,5-dioxopyrrolidin-1-yl)hexanoate","decyl-6-(2,5-dioxopyrrolidin-1-yl)hexanoate","C571771",0,0,0,0,1]
["dermonecrotic toxin, Pasteurella multocida","dermonecrotic toxin, Pasteurella multocida","C052804",0,0,0,0,1]
["Dexmedetomidine","Dexmedetomidine","D020927",4,0,4,7,1]
["diarachidonyl diglyceride","diarachidonyl diglyceride","C035561",0,0,0,1,1]
["dichloroformoxine","dichloroformoxine","C038629",0,0,0,0,1]
["diethylamine","diethylamine","C034281",0,0,0,0,1]
["dihydroarteannuin","dihydroarteannuin","C513609",0,0,0,0,1]
["dimegin(2,4-di-methoxyethyl)-deuteroporphyrin IX","dimegin(2,4-di-methoxyethyl)-deuteroporphyrin IX","C115898",0,0,0,0,1]
["dimethylmethoxyethylretinoic acid","dimethylmethoxyethylretinoic acid","C031119",0,0,0,0,1]
["diolein","diolein","C013965",3,3,0,1,1]
["diproxamine","diproxamine","C078439",0,0,0,0,1]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291",30,0,0,0,1]
["Dutasteride","Dutasteride","D000068538",0,3,0,0,1]
["edoxaban","edoxaban","C552171",1,0,0,0,1]
["endotoxin, Escherichia coli","endotoxin, Escherichia coli","C044101",6,0,1,7,1]
["enterotoxin D, Staphylococcal","enterotoxin D, Staphylococcal","C019368",0,0,1,10,1]
["epiglucan","epiglucan","C033671",0,0,2,12,1]
["Eriochrome Black T","Eriochrome Black T","C014527",1,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4356,B4356)","v":"essential 303 forte"},"essential 303 forte","C011246",0,0,0,0,1]
["ethyl ferulate","ethyl ferulate","C099085",0,0,0,0,1]
["ethylene dodecanedioate","ethylene dodecanedioate","C571594",0,0,0,0,1]
["Eudragit RS","Eudragit RS","C050528",0,3,0,0,1]
["fenamic acid","fenamic acid","C001209",1,0,0,0,1]
["ferrocene","ferrocene","C004998",16,0,0,3,1]
["Fludrocortisone","Fludrocortisone","D005438",1,0,0,0,1]
["Fluphenazine","Fluphenazine","D005476",6,0,1,3,1]
["fosetyl-Al","fosetyl-Al","C053504",0,0,0,0,1]
["fulvic acid","fulvic acid","C005023",1,0,2,0,1]
["gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate","gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate","C050823",5,0,0,0,1]
["gambogic acid","gambogic acid","C052659",3,0,0,9,1]
["genipin","genipin","C007834",1,0,0,0,1]
["ginsenoside Rg5","ginsenoside Rg5","C572381",2,1,0,0,1]
["ginsenoside Rh2","ginsenoside Rh2","C055305",4,6,0,2,1]
["glycidyl ethers","glycidyl ethers","C020344",0,0,0,0,1]
["GuttaFlow","GuttaFlow","C515718",0,0,0,0,1]
["gyrophoric acid","gyrophoric acid","C120727",0,6,0,0,1]
["hexabromocyclododecane","hexabromocyclododecane","C089796",0,0,1,1,1]
["hexyl acrylate","hexyl acrylate","C526535",0,0,0,0,1]
["hexyl salicylate","hexyl salicylate","C526485",0,0,0,0,1]
["hydroxypropyl-gamma-cyclodextrin","hydroxypropyl-gamma-cyclodextrin","C479659",0,0,0,0,1]
["ImuVert","ImuVert","C062792",0,0,0,1,1]
["iobitridol","iobitridol","C093233",0,0,0,0,1]
["isoamyl salicylate","isoamyl salicylate","C010203",0,0,0,0,1]
["isometamidium-dextran complex","isometamidium-dextran complex","C025636",0,0,0,0,1]
["isopropyl piperate","isopropyl piperate","C000602012",0,0,0,0,1]
["jingui shenqi","jingui shenqi","C510025",0,0,0,0,1]
["kadsuralignan F","kadsuralignan F","C000601357",0,0,0,0,1]
["karanjin","karanjin","C052068",0,0,0,0,1]
["Kloroperka","Kloroperka","C029585",0,0,0,0,1]
["Kynurenic Acid","Kynurenic Acid","D007736",13,0,1,1,1]
["lapachol","lapachol","C008252",0,3,0,3,1]
["levomecol","levomecol","C054376",0,0,0,0,1]
["licoricidin","licoricidin","C401293",0,0,0,0,1]
["lipopolysaccharide, E. coli O26-B6","lipopolysaccharide, E. coli O26-B6","C433788",0,1,1,0,1]
["lormetazepam","lormetazepam","C023842",0,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4612,B4612)","v":"lysenin"},"lysenin","C107040",12,0,0,0,1]
["mahanine","mahanine","C465290",1,0,0,0,1]
["Mal f 3 allergen","Mal f 3 allergen","C113871",0,0,0,0,1]
["manganese(III)-tetrakis(4-benzoic acid)porphyrin","manganese(III)-tetrakis(4-benzoic acid)porphyrin","C097284",0,3,0,5,1]
["Meclofenoxate","Meclofenoxate","D002504",1,0,0,0,1]
["Menogaril","Menogaril","D017290",0,0,0,3,1]
["methamidophos","methamidophos","C014655",2,0,0,0,1]
["methyl 3-oxo-2-(pent-2-enyl)cyclopentaneacetate","methyl 3-oxo-2-(pent-2-enyl)cyclopentaneacetate","C578021",0,0,0,0,1]
["methyl linoleate","methyl linoleate","C005575",0,0,0,1,1]
["methylformamide","methylformamide","C002950",1,0,0,0,1]
["methylphenyl carbinol","methylphenyl carbinol","C002017",0,0,0,0,1]
["Metribolone","Metribolone","D015741",7,3,0,0,1]
["milbemycin","milbemycin","C027837",2,0,0,0,1]
["MK 458","MK 458","C071191",0,0,0,0,1]
["monomethylarsonic acid","monomethylarsonic acid","C020300",0,1,0,0,1]
["morphine propionate","morphine propionate","C523259",0,0,0,0,1]
["muscone","muscone","C031021",0,0,0,0,1]
["N-(1-(3,5-difluoro-4-methanesulfonylaminophenyl)ethyl)-3-(2-propyl-6-trifluoromethylpyridine-3-yl)acrylamide","N-(1-(3,5-difluoro-4-methanesulfonylaminophenyl)ethyl)-3-(2-propyl-6-trifluoromethylpyridine-3-yl)acrylamide","C559614",0,0,0,0,1]
["N-(3,5-dimethylphenyl)-3-methoxybenzamide","N-(3,5-dimethylphenyl)-3-methoxybenzamide","C553150",0,0,0,0,1]
["N-(carboxymethyl)chitosan","N-(carboxymethyl)chitosan","C068302",0,0,0,0,1]
["Nalorphine","Nalorphine","D009269",1,0,0,0,1]
["naphtho(1,2-b)fluoranthene","naphtho(1,2-b)fluoranthene","C065242",0,0,0,0,1]
["NE 21610","NE 21610","C065373",0,0,0,0,1]
["N-hydroxycinnamoyltyramine","N-hydroxycinnamoyltyramine","C414744",0,0,0,0,1]
["Niclosamide","Niclosamide","D009534",5,0,3,8,1]
["nileprost","nileprost","C038832",0,0,0,0,1]
["N-nitrosodiethanolamine","N-nitrosodiethanolamine","C014129",0,0,0,0,1]
["N-nitrosomorpholine","N-nitrosomorpholine","C002741",0,0,0,0,1]
["norgestimate","norgestimate","C017576",1,0,0,0,1]
["NVC-422","NVC-422","C560851",2,0,0,0,1]
["NZ 107","NZ 107","C062698",0,0,0,0,1]
["Oleandomycin","Oleandomycin","D009827",6,0,2,0,1]
["ONO 4007","ONO 4007","C086889",0,0,3,12,1]
["ONO AE 248","ONO AE 248","C121546",0,3,0,3,1]
["oxacyclohexadec-12(13)-en-2-one","oxacyclohexadec-12(13)-en-2-one","C571568",0,0,0,0,1]
["Oxymorphone","Oxymorphone","D010111",3,0,0,0,1]
["palmatine","palmatine","C005413",6,0,0,0,1]
["parecoxib","parecoxib","C409945",1,0,0,0,1]
["pei tu qing xin","pei tu qing xin","C000606437",0,0,0,0,1]
["penciclovir","penciclovir","C053539",1,0,0,0,1]
["perfluorooctane sulfonic acid","perfluorooctane sulfonic acid","C076994",13,0,0,18,1]
["perifosine","perifosine","C105905",0,1,0,0,1]
["phenylamil","phenylamil","C047088",1,0,0,0,1]
["phospholipon 90G","phospholipon 90G","C585968",0,3,0,0,1]
["Phytic Acid","Phytic Acid","D010833",81,4,0,0,1]
["piperazine-N,N'-bis(2-ethanesulfonic acid)","piperazine-N,N'-bis(2-ethanesulfonic acid)","C008916",0,0,0,0,1]
["p-isopropylbenzyl acetate","p-isopropylbenzyl acetate","C577717",0,0,0,0,1]
["Plicamycin","Plicamycin","D008926",14,0,0,7,1]
["poly(2-methacryloyloxyethyl-phosphorylcholine)","poly(2-methacryloyloxyethyl-phosphorylcholine)","C115766",3,1,0,0,1]
["poly(ethylene glycol)diacrylate","poly(ethylene glycol)diacrylate","C437167",1,0,0,0,1]
["poly(pyromellitylimidoalanine-co-1,6-bis(carboxyphenoxy)hexane)","poly(pyromellitylimidoalanine-co-1,6-bis(carboxyphenoxy)hexane)","C115154",0,0,0,0,1]
["polydextrose","polydextrose","C033375",0,0,0,1,1]
["polyhexamethyleneguanidine","polyhexamethyleneguanidine","C060540",0,0,0,6,1]
["poriferasterol monoglucoside","poriferasterol monoglucoside","C054293",0,0,0,0,1]
["PQQ Cofactor","PQQ Cofactor","D045542",10,0,0,0,1]
["prednisolone farnesylate","prednisolone farnesylate","C080069",0,0,0,0,1]
["propionaldehyde","propionaldehyde","C005556",0,0,0,0,1]
["Prostaglandins A","Prostaglandins A","D011454",10,0,6,7,1]
["purine","purine","C030985",16,0,1,16,1]
["pyridazine","pyridazine","C062482",2,0,0,0,1]
["pyrrolidine dithiocarbamic acid","pyrrolidine dithiocarbamic acid","C020972",14,2,1,11,1]
["queuine","queuine","C019549",0,0,0,0,1]
["radafaxine","radafaxine","C496215",0,0,0,0,1]
["reticuline","reticuline","C003298",0,3,0,0,1]
["rhodamine isothiocyanate","rhodamine isothiocyanate","C027755",0,0,1,0,1]
["Rimantadine","Rimantadine","D012299",8,0,0,0,1]
["Rose Bengal","Rose Bengal","D012395",19,0,4,2,1]
["S 1 (combination)","S 1 (combination)","C079198",0,0,4,3,1]
["S-2 (4-aminobutylamino)ethylphenylsulfide","S-2 (4-aminobutylamino)ethylphenylsulfide","C438647",0,0,0,0,1]
["salubrinal","salubrinal","C496827",0,0,0,0,1]
["sarolaner","sarolaner","C000623191",0,0,0,0,1]
["savirin","savirin","C000600149",0,0,0,0,1]
["Selenic Acid","Selenic Acid","D064586",0,3,0,0,1]
["Silica Gel","Silica Gel","D058428",5,3,0,0,1]
["sitaxsentan","sitaxsentan","C106276",0,0,0,0,1]
["SM 10902","SM 10902","C086698",0,3,0,0,1]
["sodium sulfate","sodium sulfate","C012036",3,0,0,0,1]
["solasulfone","solasulfone","C009799",0,0,0,0,1]
["spiropyran","spiropyran","C088184",0,0,0,0,1]
["stearoylarachidonylglycerol","stearoylarachidonylglycerol","C037149",0,0,0,0,1]
["stearyl glycyrrhetinate","stearyl glycyrrhetinate","C013689",0,0,0,0,1]
["sulfathiazole","sulfathiazole","C005312",2,0,0,0,1]
["tamol","tamol","C108021",0,0,0,0,1]
["Taurocholic Acid","Taurocholic Acid","D013656",24,0,0,8,1]
["teepol","teepol","C003381",0,0,0,0,1]
["tert-butyl peroxybenzoate","tert-butyl peroxybenzoate","C060534",0,0,0,0,1]
["tetrachlorophenol","tetrachlorophenol","C009408",0,0,0,0,1]
["tetramethrin","tetramethrin","C009424",0,0,0,0,1]
["thiazolidine-2,4-dione","thiazolidine-2,4-dione","C500090",2,0,0,0,1]
["thyrsiflorin C","thyrsiflorin C","C415031",0,0,0,0,1]
["tisopurine","tisopurine","C005832",0,0,0,0,1]
["tobacco tar","tobacco tar","C024746",0,0,0,12,1]
["Topotecan","Topotecan","D019772",10,0,6,9,1]
["traumatic acid","traumatic acid","C509089",0,0,0,0,1]
["Triad resin","Triad resin","C060386",0,0,0,0,1]
["trichlorometaphos-3","trichlorometaphos-3","C009532",0,0,0,0,1]
["Trifluoroethanol","Trifluoroethanol","D014270",20,0,0,0,1]
["tripropylene glycol diacrylate","tripropylene glycol diacrylate","C105815",0,3,0,0,1]
["TRK 820","TRK 820","C111212",5,0,0,0,1]
["tungstate","tungstate","C045951",10,0,0,0,1]
["uracoina-1","uracoina-1","C433203",0,0,0,0,1]
["valrubicin","valrubicin","C016163",1,7,0,3,1]
["Veratrine","Veratrine","D014702",0,0,0,0,1]
["VUFB 13468","VUFB 13468","C034234",0,0,0,0,1]
["WR 77913","WR 77913","C035284",0,0,0,0,1]
["Xanthine","Xanthine","D019820",4,0,1,2,1]
["xylosyl-1-4-xylosyl-1-(4-methylumbelliferone)","xylosyl-1-4-xylosyl-1-(4-methylumbelliferone)","C091993",0,0,0,0,1]
["YM 158","YM 158","C115704",0,0,0,0,1]
["Zeranol","Zeranol","D015029",3,0,0,0,1]
["zinc sulfide","zinc sulfide","C031238",5,6,0,0,1]
["(((((4-hydroxy-4,4-diphosphonobutyl)carbamoylmethyl)carbamoylmethyl)carbamoylmethyl)carbamoylmethanethiolate)oxorhenium(V)","(((((4-hydroxy-4,4-diphosphonobutyl)carbamoylmethyl)carbamoylmethyl)carbamoylmethyl)carbamoylmethanethiolate)oxorhenium(V)","C517422",2,0,0,0,0]
["((7R)-7-(((4-fluorophenyl)sulfonyl)(methyl)amino)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)acetic acid","((7R)-7-(((4-fluorophenyl)sulfonyl)(methyl)amino)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)acetic acid","C554899",1,0,0,0,0]
["(1-(2,2-diphenyl-(1,3)dioxolan-4-yl)-ethyl)-dimethyl-amine","(1-(2,2-diphenyl-(1,3)dioxolan-4-yl)-ethyl)-dimethyl-amine","C425227",2,0,0,0,0]
["(1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine)dichloroplatinum (II)","(1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine)dichloroplatinum (II)","C078283",1,0,0,3,0]
["(1R,4S,6R)-N-((1R)-2-(4-cyclohexyl-4-(((1,1-dimethylethyl)amino)carbonyl)-1-piperidinyl-1-((4-fluorophenyl)methyl)-2-oxoethyl)-2-methyl-2-azabicyclo(2.2.2)octane-6-carboxamide)","(1R,4S,6R)-N-((1R)-2-(4-cyclohexyl-4-(((1,1-dimethylethyl)amino)carbonyl)-1-piperidinyl-1-((4-fluorophenyl)methyl)-2-oxoethyl)-2-methyl-2-azabicyclo(2.2.2)octane-6-carboxamide)","C504378",1,0,0,0,0]
["(2-((2-((dimethylamino)methyl)-4-iodophenyl)thio)phenyl)methanol","(2-((2-((dimethylamino)methyl)-4-iodophenyl)thio)phenyl)methanol","C581853",1,0,0,0,0]
["(2,2'-bipyridine)(octylglycinato)palladium(II) nitrate","(2,2'-bipyridine)(octylglycinato)palladium(II) nitrate","C481806",2,0,0,0,0]
["(2S)-2-(4-(3-azidophenyl)-2-oxopyrrolidin-1-yl)butanamide","(2S)-2-(4-(3-azidophenyl)-2-oxopyrrolidin-1-yl)butanamide","C487592",1,0,0,0,0]
["(2S)-3-(2',5'-dichlorobiphenyl-4-yl)-2-(((1-(2-methoxybenzoyl)piperidin-3-yl)carbonyl)amino)propanoic acid","(2S)-3-(2',5'-dichlorobiphenyl-4-yl)-2-(((1-(2-methoxybenzoyl)piperidin-3-yl)carbonyl)amino)propanoic acid","C519332",0,0,0,3,0]
["(3-aminohexahydroazepine)dichloroplatinum(II)","(3-aminohexahydroazepine)dichloroplatinum(II)","C105315",1,0,0,0,0]
["(4-(dimethylamino)phenyl)(5-iodobenzofuran-2-yl)methanone","(4-(dimethylamino)phenyl)(5-iodobenzofuran-2-yl)methanone","C561764",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5444,B5444)","v":"(4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride"},"(4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride","D008455",1,0,0,0,0]
["(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","C546624",1,0,3,15,0]
["(7-(2-(4-difluorophenyl)-1-piperazinyl)ethyl)-2-(2-furanyl)-7H-pyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-amine","(7-(2-(4-difluorophenyl)-1-piperazinyl)ethyl)-2-(2-furanyl)-7H-pyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-amine","C534887",1,0,0,0,0]
["(9H-purin-6-yl)thiomethyl glutamate","(9H-purin-6-yl)thiomethyl glutamate","C108537",0,0,0,3,0]
["(E)-9-(2-nitrovinyl)anthracene","(E)-9-(2-nitrovinyl)anthracene","C000599593",1,0,0,0,0]
["(N-2-amino-N-2-methylamino-2,2,1-bicycloheptane)dichloroplatinum(II)","(N-2-amino-N-2-methylamino-2,2,1-bicycloheptane)dichloroplatinum(II)","C095675",1,0,0,0,0]
["(N-benzoyl)-5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-N-4-azidobenzoylpentylamine","(N-benzoyl)-5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-N-4-azidobenzoylpentylamine","C060845",1,0,0,0,0]
["(S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido)ethyl) benzoic acid","(S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido)ethyl) benzoic acid","C523467",1,0,0,0,0]
["1-((2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)pyridin-3-yl)methyl)-3-(3-oxo-3,4-dihydro-2H-benzo(b)(1,4)oxazin-8-yl)urea","1-((2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)pyridin-3-yl)methyl)-3-(3-oxo-3,4-dihydro-2H-benzo(b)(1,4)oxazin-8-yl)urea","C000624293",1,0,0,0,0]
["1-((2-methylbenzimidazol-1-yl)methyl)-2-oxoindolin-3-ylidene)amino)thiourea","1-((2-methylbenzimidazol-1-yl)methyl)-2-oxoindolin-3-ylidene)amino)thiourea","C000613466",1,0,0,0,0]
["1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine","1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine","C056415",2,0,0,0,0]
["1-(1-naphthyl)piperazine","1-(1-naphthyl)piperazine","C048241",1,0,0,0,0]
["1-(2-(4-(4-fluorobenzyl)-4-hydroxypiperidin-1-yl)ethyl)-3-(thieno(3,2-b)pyridin-7-yl)urea","1-(2-(4-(4-fluorobenzyl)-4-hydroxypiperidin-1-yl)ethyl)-3-(thieno(3,2-b)pyridin-7-yl)urea","C000600089",1,0,0,0,0]
["1-(2-(bis(phenyl)methoxy)ethyl)-4-(3-(3'-azidophenyl)propyl)piperazine","1-(2-(bis(phenyl)methoxy)ethyl)-4-(3-(3'-azidophenyl)propyl)piperazine","C068380",1,0,0,0,0]
["1-(2',6'-difluorophenyl)-1H,3H-thiazolo(3,4-a)benzimidazole","1-(2',6'-difluorophenyl)-1H,3H-thiazolo(3,4-a)benzimidazole","C073244",1,0,0,3,0]
["1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole","1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole","C472829",2,0,0,6,0]
["1-(2-methoxy-phenyl)-4-(4-(4-(6-imidazol(2,1-b) thiazolyl)-phenoxy)-butyl-4-(14)C)-piperazine dimethane","1-(2-methoxy-phenyl)-4-(4-(4-(6-imidazol(2,1-b) thiazolyl)-phenoxy)-butyl-4-(14)C)-piperazine dimethane","C427703",2,0,0,0,0]
["1-(2-pyridinyl)piperazine","1-(2-pyridinyl)piperazine","C052140",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5572,B5572)","v":"1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-morpholino-1H-pyrrole-2,5-dione"},"1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-morpholino-1H-pyrrole-2,5-dione","C579728",1,0,0,0,0]
["1-(3-dimethylaminopropyl)-3-ethylurea","1-(3-dimethylaminopropyl)-3-ethylurea","C477080",0,0,0,3,0]
["1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid","1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid","C578989",0,0,3,3,0]
["1-(4-(4-(3-oxa-8-azabicyclo(3.2.1)octan-8-yl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-(pyridin-4-yl)urea","1-(4-(4-(3-oxa-8-azabicyclo(3.2.1)octan-8-yl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-(pyridin-4-yl)urea","C549124",1,0,0,0,0]
["1-(4-aminosulfonylphenylazo)-2-naphthol-6,8-disulfonate","1-(4-aminosulfonylphenylazo)-2-naphthol-6,8-disulfonate","C000610400",1,0,0,0,0]
["1-(4-fluoro-2-(2-nitrovinyl)phenyl)pyrrolidine","1-(4-fluoro-2-(2-nitrovinyl)phenyl)pyrrolidine","C000601182",2,0,0,0,0]
["1-(4-phenyldiazenylphenyl)pyrrole-2,5-dione","1-(4-phenyldiazenylphenyl)pyrrole-2,5-dione","C546415",1,0,0,0,0]
["1-(5-chloroindol-3-yl)-3-hydroxy-3-(2H-tetrazol-5-yl)propenone","1-(5-chloroindol-3-yl)-3-hydroxy-3-(2H-tetrazol-5-yl)propenone","C400757",2,0,0,0,0]
["1-(benzo(d)(1,2,3)thiadiazol-6-yl)-3-(2-cyclohexenylethyl)urea","1-(benzo(d)(1,2,3)thiadiazol-6-yl)-3-(2-cyclohexenylethyl)urea","C576979",1,0,0,0,0]
["1-(N-methyl-4,4'-bipyridinium)-1-(2-hydroxy-5-nitrophenyl)methane","1-(N-methyl-4,4'-bipyridinium)-1-(2-hydroxy-5-nitrophenyl)methane","C066054",0,0,1,0,0]
["1,1',1'',1'''-(ethylenedinitrilo)tetra-2-propanol","1,1',1'',1'''-(ethylenedinitrilo)tetra-2-propanol","C010629",0,3,0,0,0]
["1,15-bis(ethylamino)-4,8,12-triazapentadecane","1,15-bis(ethylamino)-4,8,12-triazapentadecane","C094172",1,0,0,0,0]
["1,1'-dideoxygossypol","1,1'-dideoxygossypol","C094630",1,0,0,0,0]
["1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid","1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid","C078986",2,0,0,0,0]
["1,2,5-thiadiazolidin-3-one 1,1-dioxide","1,2,5-thiadiazolidin-3-one 1,1-dioxide","C428430",2,0,0,0,0]
["1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3","1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3","C408047",0,0,3,3,0]
["1,25-dihydroxy-26-(hydroxymethyl)vitamin D3","1,25-dihydroxy-26-(hydroxymethyl)vitamin D3","C560304",1,0,0,0,0]
["1,2-bis(heptanylcarbamoyl)glycerol 3-sulfate","1,2-bis(heptanylcarbamoyl)glycerol 3-sulfate","C049394",1,0,0,0,0]
["1,2-dibromo-3-chloropropane","1,2-dibromo-3-chloropropane","C007318",2,0,0,0,0]
["1,2-dihydroxynaphthalene","1,2-dihydroxynaphthalene","C050642",1,0,0,0,0]
["1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine","1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine","C108836",1,0,0,0,0]
["1,2-dipalmitoyl-3-phosphatidylethanolamine","1,2-dipalmitoyl-3-phosphatidylethanolamine","C007510",5,0,5,0,0]
["1,2-isopropylidene-6-chloro-deoxyglucofuranose","1,2-isopropylidene-6-chloro-deoxyglucofuranose","C055776",0,0,0,3,0]
["1,3,4-butanetriol","1,3,4-butanetriol","C114589",1,0,0,0,0]
["1,3,6-tri-O-galloylglucopyranose","1,3,6-tri-O-galloylglucopyranose","C106217",1,0,0,0,0]
["1,3-di-(4-amidinophenoxy)-2,2-bis-(4-amidinophenoxymethyl)propane","1,3-di-(4-amidinophenoxy)-2,2-bis-(4-amidinophenoxymethyl)propane","C057885",0,0,0,1,0]
["1,3-dichloro-6-trifluoromethyl-9-phenanthryl-3-(n-butyl)aminopropanol","1,3-dichloro-6-trifluoromethyl-9-phenanthryl-3-(n-butyl)aminopropanol","C044961",2,0,0,0,0]
["1,3-mannosylmannose","1,3-mannosylmannose","C108662",1,0,0,0,0]
["1,4-benzothiazine","1,4-benzothiazine","C446962",1,0,0,3,0]
["1,4-bis((4-((4-heptylpiperazin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)methyl)benzene","1,4-bis((4-((4-heptylpiperazin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)methyl)benzene","C000608078",1,0,0,0,0]
["1,4-glucan","1,4-glucan","C040088",5,0,0,0,0]
["1,6-bis(4,7-diaza-6-methyl-5-oxo-3-((2-((5-(phenylthio)tetrazol-1-yl)methyl)pyrrolidin-1-yl)carbonyl)octyloxy)-2,4-hexadiyne","1,6-bis(4,7-diaza-6-methyl-5-oxo-3-((2-((5-(phenylthio)tetrazol-1-yl)methyl)pyrrolidin-1-yl)carbonyl)octyloxy)-2,4-hexadiyne","C491032",2,0,0,0,0]
["1,6-bis(carboxyphenoxy)hexane","1,6-bis(carboxyphenoxy)hexane","C120991",0,0,3,0,0]
["10-(2-(4-methoxyphenyl)-2-oxoethylidene)-10H-anthracen-9-one","10-(2-(4-methoxyphenyl)-2-oxoethylidene)-10H-anthracen-9-one","C550360",1,0,0,0,0]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430",1,0,0,23,0]
["10-decarboxymethylaclacinomycin T","10-decarboxymethylaclacinomycin T","C478393",1,0,0,0,0]
["10-nitro-oleic acid","10-nitro-oleic acid","C521487",0,3,0,0,0]
["11,12-epoxyeicosatrienoic acid methyl ester","11,12-epoxyeicosatrienoic acid methyl ester","C515338",1,0,0,0,0]
["11,13-dihydroxy-14-octadecaenoic acid","11,13-dihydroxy-14-octadecaenoic acid","C067685",2,0,0,0,0]
["11-methoxygelselegine","11-methoxygelselegine","C576442",0,0,0,3,0]
["12-doxylstearate methyl ester","12-doxylstearate methyl ester","C024283",1,0,0,0,0]
["12-nitrofolic acid","12-nitrofolic acid","C468780",1,0,0,0,0]
["13-cis-retinal","13-cis-retinal","C031338",2,0,0,0,0]
["14-(ethylamino)-8,9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione","14-(ethylamino)-8,9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione","C545120",1,3,0,1,0]
["14-desoxo-3beta,5alpha,7beta,10,15beta-O-pentaacetyl-14alpha-O-benzoyl-10,18-dihydromyrinsol","14-desoxo-3beta,5alpha,7beta,10,15beta-O-pentaacetyl-14alpha-O-benzoyl-10,18-dihydromyrinsol","C554709",0,0,0,3,0]
["15,15'-didehydroastaxanthin","15,15'-didehydroastaxanthin","C052906",1,0,0,0,0]
["15-acetyldeoxynivalenol","15-acetyldeoxynivalenol","C046760",0,0,0,3,0]
["15-oxospiramilactone","15-oxospiramilactone","C560615",2,0,0,0,0]
["16-fluoro-5-androsten-17-one","16-fluoro-5-androsten-17-one","C066783",0,0,0,1,0]
["17,18,19,20-tetranor-16-(3-biphenyl)-2,3,13,14-tetradehydroprostaglandin E1","17,18,19,20-tetranor-16-(3-biphenyl)-2,3,13,14-tetradehydroprostaglandin E1","C561620",0,0,0,3,0]
["17-cyclopropylmethyl-6,7-didehydro-quinolino(2',3'-6,7)morphinan-4-ol","17-cyclopropylmethyl-6,7-didehydro-quinolino(2',3'-6,7)morphinan-4-ol","C572008",2,0,0,0,0]
["18F-ST889","18F-ST889","C574177",1,0,0,0,0]
["19-nor-1,24,25,28-tetrahydroxyvitamin D2","19-nor-1,24,25,28-tetrahydroxyvitamin D2","C426834",0,1,0,0,0]
["1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine","1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine","C078632",1,0,0,0,0]
["1-aminoanthracene","1-aminoanthracene","C049062",2,0,0,0,0]
["1-azafagomine","1-azafagomine","C414749",1,0,0,0,0]
["1-benzyl-N-(2,6-dimethylphenyl)-3-pyrrolidine carboxamide","1-benzyl-N-(2,6-dimethylphenyl)-3-pyrrolidine carboxamide","C553457",1,0,0,0,0]
["1-bromo-2,5-bis(4-hydroxystyryl)benzene","1-bromo-2,5-bis(4-hydroxystyryl)benzene","C507418",1,0,0,0,0]
["1-carbapen-2-em-3-carboxylic acid","1-carbapen-2-em-3-carboxylic acid","C093704",1,0,0,0,0]
["1-deoxygluco-heptulose 2-phosphate","1-deoxygluco-heptulose 2-phosphate","C044547",1,0,0,0,0]
["1-ethyl-3-(3-dimethylaminoethyl)carbodiimide","1-ethyl-3-(3-dimethylaminoethyl)carbodiimide","C074139",1,0,0,0,0]
["1H-tetrazole","1H-tetrazole","C045574",5,0,0,0,0]
["1-hydroxymethylmidazolam","1-hydroxymethylmidazolam","C040081",4,0,0,0,0]
["1-methyl-1,2,3,4-tetrahydroisoquinoline","1-methyl-1,2,3,4-tetrahydroisoquinoline","C050386",2,0,0,0,0]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632",36,0,0,29,0]
["1-methylpyrene","1-methylpyrene","C053035",0,3,0,0,0]
["1-N-(4-sulfamoylphenylethyl)-2,4,6-trimethylpyridinium","1-N-(4-sulfamoylphenylethyl)-2,4,6-trimethylpyridinium","C504985",1,0,0,0,0]
["1-naphthyl alpha-truxillate","1-naphthyl alpha-truxillate","C000621416",1,0,0,0,0]
["1-O-(3-(4-benzoyldihydrocinnamidiyl)propyl)-myoinositol 1,4,5-trisphosphate","1-O-(3-(4-benzoyldihydrocinnamidiyl)propyl)-myoinositol 1,4,5-trisphosphate","C106618",1,0,0,0,0]
["1-oleoyl-2-((N-(7-(nitro)-2,1,3-benzoxadiazol-4-yl)amino)hexanoyl)glycero-3-phosphate","1-oleoyl-2-((N-(7-(nitro)-2,1,3-benzoxadiazol-4-yl)amino)hexanoyl)glycero-3-phosphate","C086969",1,0,0,0,0]
["1-palmitoyl-2-(6-((7-nitro-2-1,3-benzoxadiazol-4-yl)amino)hexanoyl)-sn-glycero-3-phospho-L-serine","1-palmitoyl-2-(6-((7-nitro-2-1,3-benzoxadiazol-4-yl)amino)hexanoyl)-sn-glycero-3-phospho-L-serine","C519996",0,0,0,1,0]
["1-palmitoyl-2-oleoyl-glycero-3-phosphatidic acid","1-palmitoyl-2-oleoyl-glycero-3-phosphatidic acid","C103238",1,0,0,0,0]
["1-palmitoyl-2-pyrenedecanoylphosphatidylcholine","1-palmitoyl-2-pyrenedecanoylphosphatidylcholine","C021248",1,0,0,0,0]
["1-phenethylamine","1-phenethylamine","C033198",1,0,0,0,0]
["1''-phosphocholine-2''-aminodihydroxypropane-3''-phospho-6'-glucopyranosyl-(1'-3)-1,2-dipalmitoylglycerol","1''-phosphocholine-2''-aminodihydroxypropane-3''-phospho-6'-glucopyranosyl-(1'-3)-1,2-dipalmitoylglycerol","C106372",0,0,0,1,0]
["1-thioxo-1,2-dihydro(1,2,4)triazolo(4,3-a)quinoxalin-4(5H)-one","1-thioxo-1,2-dihydro(1,2,4)triazolo(4,3-a)quinoxalin-4(5H)-one","C585833",1,0,0,0,0]
["1-undecenylaldehyde","1-undecenylaldehyde","C546677",1,0,0,0,0]
["2-((2-(3,4-dichlorophenyl)ethyl)propylamino)-1-pyridin-3-ylethanol","2-((2-(3,4-dichlorophenyl)ethyl)propylamino)-1-pyridin-3-ylethanol","C512156",1,0,0,0,0]
["2-((4-tert-butylphenoxy)methyl)-5-methyl-2,3-dihydroimidazo(2,1-b)(1,3)oxazole-6-carboxamide","2-((4-tert-butylphenoxy)methyl)-5-methyl-2,3-dihydroimidazo(2,1-b)(1,3)oxazole-6-carboxamide","C000595260",1,0,0,0,0]
["2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide","2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide","C499326",0,0,0,3,0]
["2-(1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl)-1-fluorocyclopropanecarboxylic acid, 6-heptyl ester","2-(1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl)-1-fluorocyclopropanecarboxylic acid, 6-heptyl ester","C528984",1,0,0,0,0]
["2-(2-((dimethylamino)methyl)-4-(3-fluoropropoxy)phenylthio)benzenamine","2-(2-((dimethylamino)methyl)-4-(3-fluoropropoxy)phenylthio)benzenamine","C527727",3,0,0,0,0]
["2-(2-(1-(2-(tert-butylsulfonyl)-1-cyclopropylethyl)-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl)methyl)thiazol-5-yl)acetic acid","2-(2-(1-(2-(tert-butylsulfonyl)-1-cyclopropylethyl)-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl)methyl)thiazol-5-yl)acetic acid","C000589311",1,0,0,0,0]
["2-(2'-(biphenyl-3-ylmethylcarbamoyl)-6,6'-bis(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl)-4,4'-bipyridine-2-carboxamido)-2-cyclohexylacetic acid","2-(2'-(biphenyl-3-ylmethylcarbamoyl)-6,6'-bis(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl)-4,4'-bipyridine-2-carboxamido)-2-cyclohexylacetic acid","C570596",2,0,0,0,0]
["2-(2,7-dimethylpyrazolo(1,5-a)pyrimidin-6-yl)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoline","2-(2,7-dimethylpyrazolo(1,5-a)pyrimidin-6-yl)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoline","C524711",1,0,0,0,0]
["2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one","2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one","C093973",0,0,3,10,0]
["2-(2-fluoro-4-hydroxyphenyl)-3,5-bis(4-hydroxyphenyl)-1-propyl-1H-pyrrole","2-(2-fluoro-4-hydroxyphenyl)-3,5-bis(4-hydroxyphenyl)-1-propyl-1H-pyrrole","C577938",1,0,0,0,0]
["2-(3-(4-(2-isopropoxyphenyl)piperazin-1-yl)propyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione","2-(3-(4-(2-isopropoxyphenyl)piperazin-1-yl)propyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione","C541785",1,0,0,0,0]
["2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one","2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one","C539142",1,0,0,0,0]
["2-(3-hydroxy-4,5-diiodo-6H-6-oxoxanthen-9-yl)benzoic acid","2-(3-hydroxy-4,5-diiodo-6H-6-oxoxanthen-9-yl)benzoic acid","C108722",0,0,0,3,0]
["2-(4-(3-chloro-5-fluoro-6-(1H-pyrazolo(3,4-b)pyridin-3-yl)pyridin-2-yl)piperazin-2-yl)-3-methylbutan-2-ol","2-(4-(3-chloro-5-fluoro-6-(1H-pyrazolo(3,4-b)pyridin-3-yl)pyridin-2-yl)piperazin-2-yl)-3-methylbutan-2-ol","C580999",0,0,0,1,0]
["2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxylic acid amide","2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxylic acid amide","C500066",0,0,0,2,0]
["2-(4'-(dimethylamino)phenyl)benzothiazole","2-(4'-(dimethylamino)phenyl)benzothiazole","C554933",3,0,0,0,0]
["2-(4-butylphenyl)-5-(2-hydrazinylpyrimidin-4-yl)-4-methylthiazole","2-(4-butylphenyl)-5-(2-hydrazinylpyrimidin-4-yl)-4-methylthiazole","C000619431",0,3,0,0,0]
["2-(4-cyanophenyl)-N-(1-(1-(N,1-diphenylmethylsulfonamido)propan-2-yl)piperidin-4-yl)acetamide","2-(4-cyanophenyl)-N-(1-(1-(N,1-diphenylmethylsulfonamido)propan-2-yl)piperidin-4-yl)acetamide","C559487",1,0,0,0,0]
["2-(4-isobutylphenyl)propionic acid 4-(diethoxyphosphoryloxy)butyl ester","2-(4-isobutylphenyl)propionic acid 4-(diethoxyphosphoryloxy)butyl ester","C559491",1,0,0,0,0]
["2-(4-morpholinoanilino)-6-cyclohexylaminopurine","2-(4-morpholinoanilino)-6-cyclohexylaminopurine","C484369",1,0,0,0,0]
["2-(5-(4-(2-hydroxyethyl)piperazin-1-ylsulfonyl)-2-n-propoxyphenyl)-5-ethyl-7-n-propyl-3,5-dihydro-4H-pyrrolo(3,2-d)pyrimidin-4-one dihydrochloride","2-(5-(4-(2-hydroxyethyl)piperazin-1-ylsulfonyl)-2-n-propoxyphenyl)-5-ethyl-7-n-propyl-3,5-dihydro-4H-pyrrolo(3,2-d)pyrimidin-4-one dihydrochloride","C518762",1,0,0,0,0]
["2-(6-(methylamino)pyridin-3-yl)-1,3-benzothiazol-6-ol","2-(6-(methylamino)pyridin-3-yl)-1,3-benzothiazol-6-ol","C539976",2,0,0,0,0]
["2-(8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro(4.5)dec-9-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro(indene-2,3'-pyrrolo(2,3-b)pyridin)-5-yl)acetamide","2-(8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro(4.5)dec-9-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro(indene-2,3'-pyrrolo(2,3-b)pyridin)-5-yl)acetamide","C548781",1,0,0,0,0]
["2-(beta-(3-iodo-4-hydroxyphenyl)ethylaminomethyl)tetralone","2-(beta-(3-iodo-4-hydroxyphenyl)ethylaminomethyl)tetralone","C048008",1,0,0,0,0]
["2-(diethylamino)ethyl 11-(2-(diethylamino)ethoxy)-10-(2-(diethylamino)ethyl)-10H-indolo(3,2-b)quinoline-7-carboxylate","2-(diethylamino)ethyl 11-(2-(diethylamino)ethoxy)-10-(2-(diethylamino)ethyl)-10H-indolo(3,2-b)quinoline-7-carboxylate","C000602269",1,0,0,0,0]
["2-(N-morpholino)ethanesulfonic acid","2-(N-morpholino)ethanesulfonic acid","C004550",2,0,0,0,0]
["2,11-diaza-4-(2-(trifluoromethyl)phenyl)-5-(hydroxyaminocarbonyl)-1-((((morpholin-4-yl)carbonyl)methyl)aminocarbonyl)-9-oxa-3,10-dioxocyclopentadecane","2,11-diaza-4-(2-(trifluoromethyl)phenyl)-5-(hydroxyaminocarbonyl)-1-((((morpholin-4-yl)carbonyl)methyl)aminocarbonyl)-9-oxa-3,10-dioxocyclopentadecane","C438586",1,0,0,0,0]
["2,2,3,3-tetrafluoroputrescine","2,2,3,3-tetrafluoroputrescine","C049506",1,0,0,0,0]
["2,2'-bipyridin butyl dithiocarbamatopalladium(II)","2,2'-bipyridin butyl dithiocarbamatopalladium(II)","C547004",1,0,0,0,0]
["2,2-dichloro-1,1,1-trifluoroethane","2,2-dichloro-1,1,1-trifluoroethane","C067411",5,0,0,0,0]
["2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide","2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide","C545185",2,0,0,1,0]
["2,3,4,5-tetrahydro-4-(2-chlorophenyl)-2-phenyl-6-(pyrrolidin-1-yl)-1,2,4-triazin-5-one","2,3,4,5-tetrahydro-4-(2-chlorophenyl)-2-phenyl-6-(pyrrolidin-1-yl)-1,2,4-triazin-5-one","C549970",1,0,0,0,0]
["2,3,4-trimethoxy-4'-acetyl-1,1'-biphenyl","2,3,4-trimethoxy-4'-acetyl-1,1'-biphenyl","C098547",1,0,0,0,0]
["2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazolium hydroxide","2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazolium hydroxide","C059087",0,3,0,1,0]
["2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate","2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate","C419146",1,0,0,0,0]
["2,3-dihydro-7H-thiazolo(3,2,a)pyrimidin-7-one","2,3-dihydro-7H-thiazolo(3,2,a)pyrimidin-7-one","C110622",0,0,0,3,0]
["2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone","2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone","C060262",3,0,0,0,0]
["2',3'-epoxypropylglucopyranoside","2',3'-epoxypropylglucopyranoside","C007607",1,0,0,0,0]
["2,4-bis(p-hydroxyphenyl)-2-butenal","2,4-bis(p-hydroxyphenyl)-2-butenal","C580808",2,0,0,0,0]
["2,4-diaminopyridine","2,4-diaminopyridine","C026805",1,0,0,0,0]
["2,4-dichlorophenoxyacetyl-S-acyl-CoA thioester","2,4-dichlorophenoxyacetyl-S-acyl-CoA thioester","C473625",2,0,0,0,0]
["2,4-nonadienal","2,4-nonadienal","C412886",0,3,0,0,0]
["2,5-di-(2-phenethyl)pyrrolidine","2,5-di-(2-phenethyl)pyrrolidine","C555559",2,0,0,0,0]
["2,5-diketogluconate","2,5-diketogluconate","C063875",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C6404,B6404)","v":"2,6-dichloro-4-nitrophenol"},"2,6-dichloro-4-nitrophenol","C015802",1,0,0,0,0]
["2,6-dimethylphenylisonitrile","2,6-dimethylphenylisonitrile","C054450",1,0,0,0,0]
["2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol","2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol","C438607",3,0,0,0,0]
["2,7-dichlorodibenzo-4-dioxin","2,7-dichlorodibenzo-4-dioxin","C000925",0,0,0,1,0]
["20-iodo-14,15-epoxyeicosa-8-enoyl-3-azidophenylsulfonamide","20-iodo-14,15-epoxyeicosa-8-enoyl-3-azidophenylsulfonamide","C559266",1,0,0,0,0]
["20-methyl spirolide G","20-methyl spirolide G","C503463",1,0,0,0,0]
["22-hydroxycholecalciferol","22-hydroxycholecalciferol","C053469",0,3,0,0,0]
["24-norursodeoxycholic acid","24-norursodeoxycholic acid","C081331",0,0,0,3,0]
["24-O-hydroxy-7,8-didehydrohydroshengmanol-3-O-beta-D-galactopyranoside","24-O-hydroxy-7,8-didehydrohydroshengmanol-3-O-beta-D-galactopyranoside","C576428",0,0,0,3,0]
["2-acetamidoglucal","2-acetamidoglucal","C019231",1,0,0,0,0]
["2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine","2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine","C049584",3,0,0,10,0]
["2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl phosphate","2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl phosphate","C453461",0,0,0,3,0]
["2-amino-4-(4-chloro-2-(2-(4-fluoro-1H-pyrazol-1-yl)ethoxy)-6-methylphenyl)-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo(3,4-d)pyrimidine-6-carboxamide","2-amino-4-(4-chloro-2-(2-(4-fluoro-1H-pyrazol-1-yl)ethoxy)-6-methylphenyl)-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo(3,4-d)pyrimidine-6-carboxamide","C559868",2,0,0,0,0]
["2-amino-4-phosphono-propinate","2-amino-4-phosphono-propinate","C114785",1,0,0,0,0]
["2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile","2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile","C501280",0,0,0,3,0]
["2-aminoethylmethacrylate","2-aminoethylmethacrylate","C072703",0,0,3,1,0]
["2-anilinonaphthalene-6-sulfonic acid","2-anilinonaphthalene-6-sulfonic acid","C047136",3,0,0,0,0]
["2-benzoquinone","2-benzoquinone","C025225",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C6532,B6532)","v":"2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one"},"2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one","C587262",0,3,0,0,0]
["2-butyl-6-hydroxy-3-(2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl)-3H-quinazolin-4-one","2-butyl-6-hydroxy-3-(2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl)-3H-quinazolin-4-one","C499145",1,0,0,0,0]
["2-carboxylbenzaldehyde thiosemicarbazone","2-carboxylbenzaldehyde thiosemicarbazone","C521291",1,0,0,0,0]
["2-chloroethyl butyl sulfide","2-chloroethyl butyl sulfide","C061448",0,3,0,0,0]
["2-chloro-N-(ethoxymethyl)-N-(2-methyl-6-(trifluoromethyl)phenyl)acetamide","2-chloro-N-(ethoxymethyl)-N-(2-methyl-6-(trifluoromethyl)phenyl)acetamide","C078188",1,0,0,0,0]
["2-cyclohexen-1-one","2-cyclohexen-1-one","C028215",2,0,0,1,0]
["2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole","2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole","C492322",1,0,0,0,0]
["2-ethyl-8-(4-fluorophenyl)-6-methyl-3,4-dihydro-2H-(2,7)naphthyridin-1-one","2-ethyl-8-(4-fluorophenyl)-6-methyl-3,4-dihydro-2H-(2,7)naphthyridin-1-one","C528322",0,0,3,0,0]
["2-fluoro-3-(2-azetidinylmethoxy)pyridine","2-fluoro-3-(2-azetidinylmethoxy)pyridine","C119803",1,0,0,0,0]
["2-fluorobenzenesulfonamide","2-fluorobenzenesulfonamide","C060416",1,0,0,0,0]
["2-galactopyranosylglycerol","2-galactopyranosylglycerol","C457479",1,0,0,0,0]
["2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone","2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone","C120275",1,0,0,0,0]
["2-hydroxy-3-undecyl-1,4-naphthoquinone","2-hydroxy-3-undecyl-1,4-naphthoquinone","C039344",1,0,0,0,0]
["2-hydroxy-6-methylpurine","2-hydroxy-6-methylpurine","C071987",1,0,0,0,0]
["2-hydroxyisoquinoline-1,3(2H,4H)-dione","2-hydroxyisoquinoline-1,3(2H,4H)-dione","C558516",1,0,0,0,0]
["2-hydroxypyridine","2-hydroxypyridine","C017679",3,0,0,0,0]
["2-isobutyl-3-methoxypyrazine","2-isobutyl-3-methoxypyrazine","C034376",1,0,0,0,0]
["2-mercapto-1-methylimidazole","2-mercapto-1-methylimidazole","C107674",1,0,0,0,0]
["2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol","2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol","C000623019",2,0,0,0,0]
["2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide","2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide","C577942",1,0,0,0,0]
["2-methyl-1,4-hydroquinone","2-methyl-1,4-hydroquinone","C062397",1,0,0,0,0]
["2-Methyl-4-chlorophenoxyacetic Acid","2-Methyl-4-chlorophenoxyacetic Acid","D008456",8,0,0,0,0]
["2-methylene-3-hexylbutanedioic acid","2-methylene-3-hexylbutanedioic acid","C426868",2,0,0,0,0]
["2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one","2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one","C495818",0,1,0,0,0]
["2-naphthylglucoside","2-naphthylglucoside","C088461",1,0,0,0,0]
["2-nitro-7-methoxynaphtho(2-1b)furan","2-nitro-7-methoxynaphtho(2-1b)furan","C030911",1,0,0,0,0]
["2-nitrophenylmaltoside","2-nitrophenylmaltoside","C044933",1,0,0,0,0]
["2'-O-(4-methoxycinnamoyl)mussaenosidic acid","2'-O-(4-methoxycinnamoyl)mussaenosidic acid","C000600523",0,0,0,3,0]
["2-oxo-4-(pyridin-3-yl)-3-butenoic acid","2-oxo-4-(pyridin-3-yl)-3-butenoic acid","C529114",1,0,0,0,0]
["2-phenylindole","2-phenylindole","C542223",1,0,0,0,0]
["2-propyl-2-pentenoic acid","2-propyl-2-pentenoic acid","C014168",5,0,0,0,0]
["2-propyl-4-pentenoic acid","2-propyl-4-pentenoic acid","C045022",3,0,0,0,0]
["2-styrylquinazolin-4(3H)-one","2-styrylquinazolin-4(3H)-one","C071666",2,0,0,0,0]
["3 alpha-methyldigitoxigenin glucoside","3 alpha-methyldigitoxigenin glucoside","C035601",1,0,0,0,0]
["3 beta-hydroxy-delta 5-cholenic acid","3 beta-hydroxy-delta 5-cholenic acid","C014596",1,0,0,0,0]
["3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate","3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate","C028213",3,3,0,0,0]
["3-(1-(3-(biphenyl-4-ylamino)-3-oxopropyl)-1H-1,2,3-triazol-4-yl)-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid","3-(1-(3-(biphenyl-4-ylamino)-3-oxopropyl)-1H-1,2,3-triazol-4-yl)-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid","C549053",1,0,0,0,0]
["3-(1,3-benzothiazol-2-yl)-8-((bis(2-hydroxyethyl)amino)methyl)-7-hydroxy-2H-chromen-2-one","3-(1,3-benzothiazol-2-yl)-8-((bis(2-hydroxyethyl)amino)methyl)-7-hydroxy-2H-chromen-2-one","C000592899",1,0,0,0,0]
["3-(2-((phenylamino)carbonyl)ethenyl)-4,6-dichloroindole-2-carboxylic acid","3-(2-((phenylamino)carbonyl)ethenyl)-4,6-dichloroindole-2-carboxylic acid","C105319",2,0,0,0,0]
["3-(2,4-dihydroxyphenyl)propionic acid","3-(2,4-dihydroxyphenyl)propionic acid","C520847",1,0,0,0,0]
["3-(2,4-dimethoxybenzylidene)anabaseine","3-(2,4-dimethoxybenzylidene)anabaseine","C088936",2,0,0,0,0]
["3-(2-oxo-3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)pyrrolidin-1-yl)-3-quinolin-3-ylpropanoic acid","3-(2-oxo-3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)pyrrolidin-1-yl)-3-quinolin-3-ylpropanoic acid","C466950",1,0,0,0,0]
["3-(3,4-dimethylphenyl)-N-n-propylpiperidine","3-(3,4-dimethylphenyl)-N-n-propylpiperidine","C116268",1,0,0,0,0]
["3-(3-chloro-1,4-naphthoquinon-2-yl)-2-methylpropenoic acid","3-(3-chloro-1,4-naphthoquinon-2-yl)-2-methylpropenoic acid","C569501",2,0,0,0,0]
["3-(4-(4-chlorophenyl)piperazinylmethyl)pyrazolo(1,5-a)pyridine","3-(4-(4-chlorophenyl)piperazinylmethyl)pyrazolo(1,5-a)pyridine","C118215",1,0,0,0,0]
["3-(4-Amino-5-cyclopropylpyrimidine-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridine","3-(4-Amino-5-cyclopropylpyrimidine-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridine","C423582",2,0,0,0,0]
["3-(4-chloro-3-methoxyphenyl)-2-thioxoquinazoline-4-one","3-(4-chloro-3-methoxyphenyl)-2-thioxoquinazoline-4-one","C000598354",1,0,0,0,0]
["3-(4-ethylphenylmethyl)-1-(glucopyranosyl)indole","3-(4-ethylphenylmethyl)-1-(glucopyranosyl)indole","C588140",1,0,0,0,0]
["3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide","3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide","C500530",0,3,0,0,0]
["3-(5-chloroindole-2-carbonyl)amino-2-hydroxy-4-phenylbutyric acid N-methyl-N-methoxyamide","3-(5-chloroindole-2-carbonyl)amino-2-hydroxy-4-phenylbutyric acid N-methyl-N-methoxyamide","C504712",1,0,0,0,0]
["3-(adenin-9-yl)propionhistamide","3-(adenin-9-yl)propionhistamide","C040515",1,0,0,0,0]
["3-(hydroxymethyl)-1-((2-(4-(4-cyanophenyl)-2-thia0zolyl)-1-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)methyl)propoxy)methyl ester","3-(hydroxymethyl)-1-((2-(4-(4-cyanophenyl)-2-thia0zolyl)-1-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)methyl)propoxy)methyl ester","C533212",1,0,0,0,0]
["3-(trifluoromethyl)-3-(3-iodophenyl)diazirine","3-(trifluoromethyl)-3-(3-iodophenyl)diazirine","C033174",5,0,0,0,0]
["3,3'-di(3-sulfopropyl)-4,5,4',5'-dibenzo-9-ethyl-thiacarbocyanine","3,3'-di(3-sulfopropyl)-4,5,4',5'-dibenzo-9-ethyl-thiacarbocyanine","C548165",1,0,0,0,0]
["3,3'-diindolylmethane","3,3'-diindolylmethane","C016392",7,1,0,11,0]
["3,4,5-trihydroxy-2--methoxy-8,8-dimethyl-N-(hexahydro-2-oxo-6-(cyclohexylcarbonyl)oxy-2H-azepin-3-yl)non-6-enamide","3,4,5-trihydroxy-2--methoxy-8,8-dimethyl-N-(hexahydro-2-oxo-6-(cyclohexylcarbonyl)oxy-2H-azepin-3-yl)non-6-enamide","C438868",1,0,0,0,0]
["3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer","3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer","D019900",5,0,0,15,0]
["3,4-dihydro-12-hydroxy-2,2-dimethyl-2H,6H-pyrano(3,2-b)xanthen-6-one","3,4-dihydro-12-hydroxy-2,2-dimethyl-2H,6H-pyrano(3,2-b)xanthen-6-one","C581162",1,0,0,0,0]
["3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide","3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide","C575894",2,0,0,0,0]
["3,4-ethylenedioxythiophene","3,4-ethylenedioxythiophene","C000601652",1,0,0,0,0]
["3,5-dicaffeoylquinic acid","3,5-dicaffeoylquinic acid","C100434",0,0,0,3,0]
["3,5-dihydroxy-4'-methoxystilbene","3,5-dihydroxy-4'-methoxystilbene","C439024",1,0,0,0,0]
["3,5-dinitrobenzoic acid","3,5-dinitrobenzoic acid","C026017",1,0,0,0,0]
["3,7,11-tris(carboxymethyl)-3,7,11,17-tetraaza-bicyclo(11.3.1)heptadeca-1(17),13,15-triene","3,7,11-tris(carboxymethyl)-3,7,11,17-tetraaza-bicyclo(11.3.1)heptadeca-1(17),13,15-triene","C445963",0,0,0,3,0]
["3',8-dichlorogenistein","3',8-dichlorogenistein","C562014",1,0,0,0,0]
["3-acetyldeoxynivalenol","3-acetyldeoxynivalenol","C043247",0,0,0,3,0]
["3-amino-1-chloro-2-pentanone","3-amino-1-chloro-2-pentanone","C027690",1,0,0,0,0]
["3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid","3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid","C513113",0,0,0,6,0]
["3-aminobenzeneboronic acid","3-aminobenzeneboronic acid","C028592",2,0,0,0,0]
["3-aminopyridine-2-carboxaldehyde thiosemicarbazone","3-aminopyridine-2-carboxaldehyde thiosemicarbazone","C078157",2,0,0,0,0]
["3-azidiamantane","3-azidiamantane","C121999",2,0,0,0,0]
["3beta-hydroxy-urs-11-en-13beta,28-olide","3beta-hydroxy-urs-11-en-13beta,28-olide","C000597093",1,0,0,0,0]
["3-bromo-4,5-dihydroxybenzaldehyde","3-bromo-4,5-dihydroxybenzaldehyde","C580724",0,6,0,0,0]
["3-carboxy-4-methyl-5-propyl-2-furanpropionic acid","3-carboxy-4-methyl-5-propyl-2-furanpropionic acid","C041693",16,0,0,3,0]
["3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone","3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone","C054121",2,0,0,0,0]
["3-chlorocatechol","3-chlorocatechol","C031137",1,0,0,0,0]
["3-dehydroquinic acid","3-dehydroquinic acid","C474477",2,0,0,0,0]
["3-deoxysappanchalcone","3-deoxysappanchalcone","C542297",0,3,0,0,0]
["3-dimethylaminonaphtheurodine","3-dimethylaminonaphtheurodine","C030666",1,0,0,0,0]
["3-fluorocinnamic acid","3-fluorocinnamic acid","C042047",1,0,0,0,0]
["3-hydroxy-2,2',4,4',5,6'-hexabromodiphenyl ether","3-hydroxy-2,2',4,4',5,6'-hexabromodiphenyl ether","C000621705",1,0,0,0,0]
["3-hydroxy-4-(2-hydroxy-4-sulfo-1-naphthalenyl)azo","3-hydroxy-4-(2-hydroxy-4-sulfo-1-naphthalenyl)azo","C479961",1,0,0,0,0]
["3-hydroxybenzoic acid","3-hydroxybenzoic acid","C032948",1,0,0,0,0]
["3-hydroxymethyl-picumast","3-hydroxymethyl-picumast","C063141",2,0,0,0,0]
["3-hydroxyoctanoic acid","3-hydroxyoctanoic acid","C101940",2,0,0,0,0]
["3M 001","3M 001","C526116",0,0,1,3,0]
["3-methoxybenzanthrone","3-methoxybenzanthrone","C024290",0,0,0,3,0]
["3-methoxy-O-demethylencainide","3-methoxy-O-demethylencainide","C033636",1,0,0,0,0]
["3-methyleneindolenine","3-methyleneindolenine","C097745",1,0,0,0,0]
["3-methylriboflavin","3-methylriboflavin","C043310",1,0,0,0,0]
["3-morpholine-2-hydroxypropyl dextran ether","3-morpholine-2-hydroxypropyl dextran ether","C041054",0,0,0,3,0]
["3-n-pentylthio-1,1,1-trifluoro-2-propanone","3-n-pentylthio-1,1,1-trifluoro-2-propanone","C415430",1,0,0,0,0]
["3-oxo-tirucall-8,24-dien-21-oic acid","3-oxo-tirucall-8,24-dien-21-oic acid","C432163",1,0,0,0,0]
["3-phenylpropanal","3-phenylpropanal","C421487",1,0,0,0,0]
["3-sulfoglucuronyl-lacto-N-neotetraosylceramide","3-sulfoglucuronyl-lacto-N-neotetraosylceramide","C063678",1,0,0,0,0]
["4-((3-(trifluoromethyl)phenyl)methyl)-2H-1,4-benzothiazin-3(4H)-one","4-((3-(trifluoromethyl)phenyl)methyl)-2H-1,4-benzothiazin-3(4H)-one","C581707",0,0,0,3,0]
["4-((4-(1-(ethoxycarbonyl)-1-methylethoxy)-7-methyl-2-quinolyl)carbamoyl)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid","4-((4-(1-(ethoxycarbonyl)-1-methylethoxy)-7-methyl-2-quinolyl)carbamoyl)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid","C533035",2,0,0,0,0]
["4-((5-bromo-4-((2,4-dioxo-3-(2-oxo-2-phenylethyl)-1,3-thiazolidin-5-ylidene)methyl)-2-ethoxyphenoxy)methyl)benzoic acid","4-((5-bromo-4-((2,4-dioxo-3-(2-oxo-2-phenylethyl)-1,3-thiazolidin-5-ylidene)methyl)-2-ethoxyphenoxy)methyl)benzoic acid","C531217",1,0,0,0,0]
["4-(1-(4-fluorobenzyl)-4-hydroxy-1H-indol-3-yl)-2-hydroxy-4-oxobut-2-enoic acid","4-(1-(4-fluorobenzyl)-4-hydroxy-1H-indol-3-yl)-2-hydroxy-4-oxobut-2-enoic acid","C569032",2,0,0,0,0]
["4-(2-(3-aminobenzenesulfonylamino)-1-(3,5-diethoxy-2-fluorophenyl)-2-oxoethylamino)-2-hydroxybenzamidine","4-(2-(3-aminobenzenesulfonylamino)-1-(3,5-diethoxy-2-fluorophenyl)-2-oxoethylamino)-2-hydroxybenzamidine","C499651",1,0,0,0,0]
["4-(2,4-bis-(3-nitrobenzoylamino)phenoxy)phthalic acid","4-(2,4-bis-(3-nitrobenzoylamino)phenoxy)phthalic acid","C488109",1,0,0,0,0]
["4-(2-aminophenyl)-4-oxocrotonic acid","4-(2-aminophenyl)-4-oxocrotonic acid","C523757",1,0,0,0,0]
["4-(2'-methoxyphenyl)-1-(2'-(N-2'-pyridinyl)-p-(18F)fluorobenzamido )ethylpiperazine","4-(2'-methoxyphenyl)-1-(2'-(N-2'-pyridinyl)-p-(18F)fluorobenzamido )ethylpiperazine","C416325",9,0,0,0,0]
["4-(3-(2-nitro-1-imidazolyl)-propylamino)-7-chloroquinoline hydrochloride","4-(3-(2-nitro-1-imidazolyl)-propylamino)-7-chloroquinoline hydrochloride","C434187",1,0,0,0,0]
["4-(3-(benzotriazol-1-yl)propyl)-1-(2-methoxyphenyl)piperazine","4-(3-(benzotriazol-1-yl)propyl)-1-(2-methoxyphenyl)piperazine","C088974",2,0,0,0,0]
["4-(3-bromoanilino)-6,7-diethoxyquinazoline","4-(3-bromoanilino)-6,7-diethoxyquinazoline","C097783",2,0,0,0,0]
["4-(3-fluoroazetidin-1-yl)-7-methyl-5-(1-methyl-5-(4-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)imidazo(5,1-f)(1,2,4)triazine","4-(3-fluoroazetidin-1-yl)-7-methyl-5-(1-methyl-5-(4-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)imidazo(5,1-f)(1,2,4)triazine","C582922",1,0,0,0,0]
["4-(4-(4-dimethylaminophenyl)-5-phenyl-1H-imidazol-2-yl)benzoic acid methyl ester","4-(4-(4-dimethylaminophenyl)-5-phenyl-1H-imidazol-2-yl)benzoic acid methyl ester","C584462",1,0,0,0,0]
["4-(4-chlorophenyl)-2-oxo-3-butenoic acid","4-(4-chlorophenyl)-2-oxo-3-butenoic acid","C039008",1,0,0,0,0]
["4-(4-fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione","4-(4-fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione","C558674",1,0,0,0,0]
["4-(4-N-maleimidophenyl)butyric acid hydrazide","4-(4-N-maleimidophenyl)butyric acid hydrazide","C075837",1,0,0,0,0]
["4-(5-aryl-1,2,3,6-tetrahydropyridino)pyrimidine","4-(5-aryl-1,2,3,6-tetrahydropyridino)pyrimidine","C434335",2,0,0,0,0]
["4-(6-hydroxy-2-naphthyl)-1,3-benzenediol","4-(6-hydroxy-2-naphthyl)-1,3-benzenediol","C523393",0,0,0,3,0]
["4-(diphenylmethoxymethyl)-1-(3-(4-methoxyphenyl)propyl)piperidine","4-(diphenylmethoxymethyl)-1-(3-(4-methoxyphenyl)propyl)piperidine","C120256",0,0,0,3,0]
["4-(N-(2-hydroxy-2-methylpropyl)-ethanolamino)-2,7-bis(2,6-dimethylmorpholino)-6-(4-azidophenyl)pteridine","4-(N-(2-hydroxy-2-methylpropyl)-ethanolamino)-2,7-bis(2,6-dimethylmorpholino)-6-(4-azidophenyl)pteridine","C101514",1,0,0,0,0]
["4-(trifluoromethyl)benzoic acid","4-(trifluoromethyl)benzoic acid","C028383",1,0,0,0,0]
["4,4-difluoro-1,3,5,7,8-pentamethyl-4-bora-3a,4a-diaza-s-indacene","4,4-difluoro-1,3,5,7,8-pentamethyl-4-bora-3a,4a-diaza-s-indacene","C527198",1,0,0,0,0]
["4,4'-dinitro-2,2'-stilbenedisulfonic acid","4,4'-dinitro-2,2'-stilbenedisulfonic acid","C022306",2,0,0,0,0]
["4,5,6,7-tetrabromobenzotriazole","4,5,6,7-tetrabromobenzotriazole","C405354",1,6,0,0,0]
["4,5-dibromorhodamine 123","4,5-dibromorhodamine 123","C121365",0,0,6,9,0]
["4,6-bis(4-chlorophenyl)-N-(3-(2-(diethylamino)ethoxy)phenyl)pyrimidin-2-amine","4,6-bis(4-chlorophenyl)-N-(3-(2-(diethylamino)ethoxy)phenyl)pyrimidin-2-amine","C578480",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7364,B7364)","v":"4a alloantigen, human"},"4a alloantigen, human","C057260",1,0,1,0,0]
["4-acetylmethyl-3,4-dihydro-3-(2,3-dihydroxypropyl)-2,6-dimethoxy-5-nitropyrimidine","4-acetylmethyl-3,4-dihydro-3-(2,3-dihydroxypropyl)-2,6-dimethoxy-5-nitropyrimidine","C088804",0,0,0,1,0]
["4-amino-2-hydroxytoluene","4-amino-2-hydroxytoluene","C538896",0,1,0,0,0]
["4-amino-5-fluoropentanoic acid","4-amino-5-fluoropentanoic acid","C032606",1,0,0,0,0]
["4'-aminopantetheine","4'-aminopantetheine","C557399",1,0,0,0,0]
["4-anisoyl-3-(1,2,2-trimethylcyclopentane carboxylic acid)","4-anisoyl-3-(1,2,2-trimethylcyclopentane carboxylic acid)","C035519",1,0,0,0,0]
["4-azido-2-nitrophenyl phosphate","4-azido-2-nitrophenyl phosphate","C027150",2,0,0,0,0]
["4-azidosalicylic acid N-hydroxysuccinimide ester","4-azidosalicylic acid N-hydroxysuccinimide ester","C046019",3,0,0,0,0]
["4-benzoylpyridine","4-benzoylpyridine","C066738",1,0,0,0,0]
["4-carboxyfluorescein","4-carboxyfluorescein","C045132",1,0,0,0,0]
["4-carboxyphenylglyoxal","4-carboxyphenylglyoxal","C031665",1,0,0,0,0]
["4-chloronitrobenzene","4-chloronitrobenzene","C010407",1,0,0,4,0]
["4-cyclohexyl-1-ethyl-7-methylpyrido(2,3-d)pyrimidin-2-(1H)-one","4-cyclohexyl-1-ethyl-7-methylpyrido(2,3-d)pyrimidin-2-(1H)-one","C499820",1,0,0,0,0]
["4-cyclohexyloxy-2-(1-(4-(4-methoxy-benzenesulfonyl)piperazin-1-yl)ethyl)quinazoline","4-cyclohexyloxy-2-(1-(4-(4-methoxy-benzenesulfonyl)piperazin-1-yl)ethyl)quinazoline","C507255",2,0,0,0,0]
["4-dimethylamino-6-vinylpyrimidine","4-dimethylamino-6-vinylpyrimidine","C550503",1,0,0,0,0]
["4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide","4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide","C550093",2,0,0,0,0]
["4EGI-1 compound","4EGI-1 compound","C517852",7,0,0,0,0]
["4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)-1,3-thiazol-2-yl)-N-methylbenzamide","4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)-1,3-thiazol-2-yl)-N-methylbenzamide","C560416",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7492,B7492)","v":"4-hydroxy-2-hexenal"},"4-hydroxy-2-hexenal","C045934",2,0,0,0,0]
["4-hydroxy-4-(4-(2-azido-5-iodobenzyloxy)phenyl)butanoic acid","4-hydroxy-4-(4-(2-azido-5-iodobenzyloxy)phenyl)butanoic acid","C553489",1,0,0,0,0]
["4-hydroxybenzaldehyde","4-hydroxybenzaldehyde","C011483",1,0,0,0,0]
["4-hydroxyderricin","4-hydroxyderricin","C068243",1,0,0,0,0]
["4-hydroxymercuribenzoate","4-hydroxymercuribenzoate","C030601",3,0,0,0,0]
["4-hydroxyphenylacetic acid","4-hydroxyphenylacetic acid","C008070",3,0,0,0,0]
["4-hydroxyquinazoline","4-hydroxyquinazoline","C061339",2,0,0,0,0]
["4-iodo-2,5-dimethoxyphenylisopropylamine","4-iodo-2,5-dimethoxyphenylisopropylamine","C015952",3,0,0,3,0]
["4-isoavenaciolide","4-isoavenaciolide","C465357",2,0,0,0,0]
["4-ketoniridazole","4-ketoniridazole","C040636",1,0,0,0,0]
["4-methoxy-3-phenylenediamine","4-methoxy-3-phenylenediamine","C007294",2,0,0,0,0]
["4-methylamino-4'-N,N-dimethylaminoazobenzene","4-methylamino-4'-N,N-dimethylaminoazobenzene","C000612049",1,0,0,0,0]
["4-methylimidazole","4-methylimidazole","C023439",1,0,0,0,0]
["4-methylumbelliferyl glycosides","4-methylumbelliferyl glycosides","C030561",2,0,0,0,0]
["4-methylumbelliferyl-N-acetylchitotetraoside","4-methylumbelliferyl-N-acetylchitotetraoside","C027049",1,0,0,0,0]
["4-nitroacetophenone","4-nitroacetophenone","C001972",1,0,0,0,0]
["4-nitrophenol","4-nitrophenol","C024836",1,0,0,0,0]
["4-nitrophenyl beta-cellobioside","4-nitrophenyl beta-cellobioside","C034170",1,0,0,0,0]
["4-nitrophenylgalactoside","4-nitrophenylgalactoside","C059200",1,0,0,0,0]
["4'-O-(oleandrosyl)daunorubicin","4'-O-(oleandrosyl)daunorubicin","C550479",1,0,0,0,0]
["4-O-methyl glucuronoxylan","4-O-methyl glucuronoxylan","C044967",1,0,0,0,0]
["4-oxosebacic acid","4-oxosebacic acid","C434705",1,0,0,0,0]
["4-phenylbenzoic acid","4-phenylbenzoic acid","C035132",2,0,0,0,0]
["4-thioxothiazolidin-2-one","4-thioxothiazolidin-2-one","C471060",2,0,0,0,0]
["4-xylene-bis(dithiocarbamic acid)","4-xylene-bis(dithiocarbamic acid)","C550533",1,0,0,0,0]
["5-((5-chloro-1H-pyrrolo(2,3-b)pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine","5-((5-chloro-1H-pyrrolo(2,3-b)pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine","C000600259",1,0,0,3,0]
["5-(2-ethoxy-5-(N-isopropyloxycarbonyl-aminosulfonyl))-1-methyl-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-7(6H)-one","5-(2-ethoxy-5-(N-isopropyloxycarbonyl-aminosulfonyl))-1-methyl-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-7(6H)-one","C572496",1,0,0,0,0]
["5-(3,5-di-tert-butyl-4-hydroxybenzylidene)thiazolidine-2,4-dione","5-(3,5-di-tert-butyl-4-hydroxybenzylidene)thiazolidine-2,4-dione","C507175",2,0,0,0,0]
["5-(3-hydroxyphenyl)-5-phenylhydantoin","5-(3-hydroxyphenyl)-5-phenylhydantoin","C027364",2,0,0,3,0]
["5-(4-carboxyphenyl)-10,15,20-triphenylchlorin","5-(4-carboxyphenyl)-10,15,20-triphenylchlorin","C513508",1,0,0,0,0]
["5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole","5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole","C515162",1,0,0,0,0]
["5-(4-methoxyarylimino)-2-N-(3,4-dichlorophenyl)-3-oxo-1,2,4-thiadiazolidine","5-(4-methoxyarylimino)-2-N-(3,4-dichlorophenyl)-3-oxo-1,2,4-thiadiazolidine","C495275",0,0,0,1,0]
["5-(6-(5-(difluoro(methylsulfonyl)methyl)-1,3,4-oxadiazol-2-yl)-5-isopropylpyrrolo(2,1-f)(1,2,4)triazin-4-ylamino)-2,4-difluoro-N-methoxybenzamide","5-(6-(5-(difluoro(methylsulfonyl)methyl)-1,3,4-oxadiazol-2-yl)-5-isopropylpyrrolo(2,1-f)(1,2,4)triazin-4-ylamino)-2,4-difluoro-N-methoxybenzamide","C501755",1,0,0,0,0]
["5-(acetoxymethyl)-5--(hydroxymethyl)-3,3-dioctyltetrahydro-2-furanone","5-(acetoxymethyl)-5--(hydroxymethyl)-3,3-dioctyltetrahydro-2-furanone","C117319",2,0,0,0,0]
["5-(ethylpropyl)amiloride","5-(ethylpropyl)amiloride","C043988",1,0,0,0,0]
["5,2',4'-trihydroxy-6,7,5'-trimethoxyflavone","5,2',4'-trihydroxy-6,7,5'-trimethoxyflavone","C494889",1,0,0,0,0]
["5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine","5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine","C068624",1,0,0,0,0]
["5,6,7,8-tetrahydromethanopterin","5,6,7,8-tetrahydromethanopterin","C042416",1,0,0,0,0]
["5,7-diacetamido-8-O-acetyl-3,5,7,9-tetradeoxy-glycero-talo-nonulosonic acid","5,7-diacetamido-8-O-acetyl-3,5,7,9-tetradeoxy-glycero-talo-nonulosonic acid","C110570",1,0,0,0,0]
["5,7-dihydro-3-(2-(1-(phenylmethyl)-4-piperidinyl)ethyl)-6H-pyrrolo(3,2-f)-1,2-benzisoxazol-6-one","5,7-dihydro-3-(2-(1-(phenylmethyl)-4-piperidinyl)ethyl)-6H-pyrrolo(3,2-f)-1,2-benzisoxazol-6-one","C095054",1,0,0,0,0]
["5,8-dioxo-6-(pyridin-3-ylamino)-5,8-dihydronaphthalene-1-sulfonamide","5,8-dioxo-6-(pyridin-3-ylamino)-5,8-dihydronaphthalene-1-sulfonamide","C582914",1,0,0,0,0]
["5-amino-2-naphthalenesulfonate","5-amino-2-naphthalenesulfonate","C475668",1,0,0,0,0]
["5-amino-4-hydroxy-7-(4-methoxy-3-(3-methoxypropyl)benzyl)-2,8-dimethylnonanoic acid butylamide","5-amino-4-hydroxy-7-(4-methoxy-3-(3-methoxypropyl)benzyl)-2,8-dimethylnonanoic acid butylamide","C524181",1,0,0,0,0]
["5b alloantigen, human","5b alloantigen, human","C055973",0,0,0,1,0]
["5-bromo-4-oxo-2-phenylhexanoic acid","5-bromo-4-oxo-2-phenylhexanoic acid","C033400",1,0,0,0,0]
["5-bromocamphor","5-bromocamphor","C025442",1,0,0,0,0]
["5-chloro-3-ethyl-1H-indole-2-carboxylic acid (2-(4-piperidin-1-yl-phenyl)ethyl)amide","5-chloro-3-ethyl-1H-indole-2-carboxylic acid (2-(4-piperidin-1-yl-phenyl)ethyl)amide","C572504",4,0,0,0,0]
["5-chloropyrimidin-2-one","5-chloropyrimidin-2-one","C024009",1,0,0,0,0]
["5-chlorosalicylic acid","5-chlorosalicylic acid","C015751",1,0,0,0,0]
["5-enolpyruvoylshikimate-3-phosphate","5-enolpyruvoylshikimate-3-phosphate","C058070",2,0,0,0,0]
["5-fluorolevulinic acid","5-fluorolevulinic acid","C462259",1,0,0,0,0]
["5-hydroxy-2-(2-phenylethyl)chromone","5-hydroxy-2-(2-phenylethyl)chromone","C508837",1,0,0,0,0]
["5-hydroxymethylcytosine","5-hydroxymethylcytosine","C011865",11,1,0,2,0]
["5-hydroxytryptamine-tetramethylrhodamine","5-hydroxytryptamine-tetramethylrhodamine","C581847",1,0,0,0,0]
["5-iodobenzovesamicol","5-iodobenzovesamicol","C065043",2,0,0,0,0]
["5-methoxycarbonylamino-N-acetyltryptamine","5-methoxycarbonylamino-N-acetyltryptamine","C413586",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7876,B7876)","v":"5-methylnaphtho(2,1-d)oxazol-2-amine"},"5-methylnaphtho(2,1-d)oxazol-2-amine","C000591919",1,0,0,0,0]
["5-n-butyl-pyrazolo(1,5-a)pyrimidine","5-n-butyl-pyrazolo(1,5-a)pyrimidine","C547858",1,0,0,0,0]
["5-phenyl-2-(2'-(benzimidazol-5''-yl)benzimidazol-5'-yl)benzimidazole","5-phenyl-2-(2'-(benzimidazol-5''-yl)benzimidazol-5'-yl)benzimidazole","C103388",1,0,0,0,0]
["5-tert-butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo(d)isoxazole-3-carboxamide","5-tert-butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo(d)isoxazole-3-carboxamide","C000590511",1,0,0,0,0]
["6-((3-fluoro-2-hydroxy)propoxy)-2-(4-methylaminophenyl)quinoline","6-((3-fluoro-2-hydroxy)propoxy)-2-(4-methylaminophenyl)quinoline","C000604726",1,0,0,0,0]
["6-(2,5-dimethoxybenzyl)-5,6,7,8-tetrahydropyrido(2,3-d)pyrimidine-2,4-diamine","6-(2,5-dimethoxybenzyl)-5,6,7,8-tetrahydropyrido(2,3-d)pyrimidine-2,4-diamine","C496331",1,0,0,0,0]
["6-(3'-(1-adamantyl)-4'-hydroxyphenyl)-5-chloronaphthalenecarboxylic acid","6-(3'-(1-adamantyl)-4'-hydroxyphenyl)-5-chloronaphthalenecarboxylic acid","C488107",1,0,0,0,0]
["6-(4-(trifluoromethoxy)phenyl)-3-(trifluoromethyl)(1,2,4)triazolo(4,3-a)pyridine","6-(4-(trifluoromethoxy)phenyl)-3-(trifluoromethyl)(1,2,4)triazolo(4,3-a)pyridine","C578456",1,0,0,0,0]
["6-(4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one","6-(4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one","C572323",1,0,0,0,0]
["6-(N-octylanilino)uracil","6-(N-octylanilino)uracil","C095137",1,0,0,0,0]
["6,6'-dicorynomycolyl trehalose","6,6'-dicorynomycolyl trehalose","C043399",0,0,0,1,0]
["6,7-dimethoxy-3-phenylquinoxaline","6,7-dimethoxy-3-phenylquinoxaline","C106250",2,0,0,0,0]
["6A,6A'-dicyclohexylamine-6B,6B'-diselenide-bis-beta-cyclodextrin","6A,6A'-dicyclohexylamine-6B,6B'-diselenide-bis-beta-cyclodextrin","C586642",0,3,0,0,0]
["6-amino-1-hydroxyhexane-1,1-diphosphonate","6-amino-1-hydroxyhexane-1,1-diphosphonate","C053389",1,0,0,0,0]
["6-bromo-2-chloroquinoline","6-bromo-2-chloroquinoline","C534160",1,0,0,0,0]
["6-chloro-3-hydroxybenzo(b)thiophene-2-carboxylic acid","6-chloro-3-hydroxybenzo(b)thiophene-2-carboxylic acid","C576337",1,0,0,0,0]
["6-Cyano-7-nitroquinoxaline-2,3-dione","6-Cyano-7-nitroquinoxaline-2,3-dione","D018750",2,0,0,0,0]
["6-fluorobenzo(c)phenanthrene","6-fluorobenzo(c)phenanthrene","C055179",1,0,0,0,0]
["6-hydroxy-2-(naphthalen-1-ylmethyl)-1,2,4-triazine-3,5(2H,4H)-dione","6-hydroxy-2-(naphthalen-1-ylmethyl)-1,2,4-triazine-3,5(2H,4H)-dione","C000603795",1,0,0,0,0]
["6-hydroxymethylsulfadimidine","6-hydroxymethylsulfadimidine","C046745",2,0,0,0,0]
["6-methoxy-2-naphthylacetic acid","6-methoxy-2-naphthylacetic acid","C044612",2,0,0,0,0]
["6-methyl-3-(2-nitro-1-(thiophen-2-yl)propyl)-2-phenyl-1H-indole","6-methyl-3-(2-nitro-1-(thiophen-2-yl)propyl)-2-phenyl-1H-indole","C000604852",1,0,0,0,0]
["6'-methylpyrido(3,4-b)norhomotropane","6'-methylpyrido(3,4-b)norhomotropane","C501166",1,0,0,0,0]
["6-O-(2-(18F)fluoroethyl)-6-O-desmethyldiprenorphine","6-O-(2-(18F)fluoroethyl)-6-O-desmethyldiprenorphine","C411951",1,0,0,0,0]
["6-phosphonylmethoxyethoxy-2,4-diaminopyrimidine","6-phosphonylmethoxyethoxy-2,4-diaminopyrimidine","C586406",0,0,0,3,0]
["7-((4-benzylpiperazin-1-yl)methyl)-4-propyl-2H-benzo(b)(1,4)oxazin-3(4H)-one","7-((4-benzylpiperazin-1-yl)methyl)-4-propyl-2H-benzo(b)(1,4)oxazin-3(4H)-one","C000592786",1,0,0,0,0]
["7-(2,4-dichlorophenyl)pyrido(2',3'-4,5)furo(3,2-d)pyrimidin-4-amine","7-(2,4-dichlorophenyl)pyrido(2',3'-4,5)furo(3,2-d)pyrimidin-4-amine","C000589841",2,0,0,0,0]
["7-(2-methoxyethoxy)-N-((6-(3-methylisothiazol-5-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine","7-(2-methoxyethoxy)-N-((6-(3-methylisothiazol-5-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine","C556298",1,0,0,0,0]
["7-(4-(3-(1H-inden-3-yl)propyl)piperazin-1-yl)-1,3-benzoxazol-2(3H)-one","7-(4-(3-(1H-inden-3-yl)propyl)piperazin-1-yl)-1,3-benzoxazol-2(3H)-one","C546598",1,0,0,0,0]
["7-(dimethylamino)-2,3-dihydrophenanthren-4(1H)-one","7-(dimethylamino)-2,3-dihydrophenanthren-4(1H)-one","C000603231",1,0,0,0,0]
["7-(hydroxymethyl)-12-methylbenz(a)anthracene sulfate ester","7-(hydroxymethyl)-12-methylbenz(a)anthracene sulfate ester","C033702",2,0,0,0,0]
["7,8-dihydrobiopterin","7,8-dihydrobiopterin","C017226",10,0,0,0,0]
["7a-(4-octylphenethyl)tetrahydro-1H-oxazolo(3,4-c)oxazole","7a-(4-octylphenethyl)tetrahydro-1H-oxazolo(3,4-c)oxazole","C000596158",0,0,0,6,0]
["7-anilino-4-methylcoumarin-3-acetic acid","7-anilino-4-methylcoumarin-3-acetic acid","C053940",1,0,0,0,0]
["7-bromo-6-difluoromethylphosphonate 3-naphthalenenitrile","7-bromo-6-difluoromethylphosphonate 3-naphthalenenitrile","C509920",1,0,0,0,0]
["7-chloro-5((cis-3,5-dimethylpiperazine)carbonyl)imidazo(1,5a)quinoline-3-carboxylate","7-chloro-5((cis-3,5-dimethylpiperazine)carbonyl)imidazo(1,5a)quinoline-3-carboxylate","C104547",1,0,0,0,0]
["7-chloro-6-fluoro-N-(2-hydroxy-3-oxo-1-phenyl-3-(phenylamino)propyl)-4-oxo-1-(prop-2-yn-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxamide","7-chloro-6-fluoro-N-(2-hydroxy-3-oxo-1-phenyl-3-(phenylamino)propyl)-4-oxo-1-(prop-2-yn-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxamide","C583529",0,0,3,0,0]
["7-fluoro-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one","7-fluoro-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one","C000614595",1,0,0,0,0]
["7-hydroxycoumarin-3-acetic acid N-hydroxysuccinimidyl ester","7-hydroxycoumarin-3-acetic acid N-hydroxysuccinimidyl ester","C044852",0,0,1,0,0]
["7-hydroxydehydronuciferine","7-hydroxydehydronuciferine","C000611464",0,3,0,0,0]
["7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol","7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol","C507046",1,0,0,0,0]
["7-methylbenzanthracene","7-methylbenzanthracene","C021219",1,0,0,0,0]
["7-nitrobenz-2-oxa-1,3-diazol-4-yl","7-nitrobenz-2-oxa-1,3-diazol-4-yl","C510797",1,0,0,0,0]
["7-O-acetyl-GD3 ganglioside","7-O-acetyl-GD3 ganglioside","C097213",0,0,0,4,0]
["8-(1-(2,4-dichlorophenyl)-2-imidazol-1-ylethoxy)octanoic acid heptyl ester","8-(1-(2,4-dichlorophenyl)-2-imidazol-1-ylethoxy)octanoic acid heptyl ester","C515148",1,0,0,0,0]
["8-(3-(1-((3-fluorophenyl)methyl)-4-piperidinyl)-1-oxopropyl)-1,2,5,6-tetrahydro-4H-pyrrolo(3,2,1-ij)quinolin-4-one","8-(3-(1-((3-fluorophenyl)methyl)-4-piperidinyl)-1-oxopropyl)-1,2,5,6-tetrahydro-4H-pyrrolo(3,2,1-ij)quinolin-4-one","C496138",2,0,0,0,0]
["8-(4-sulfophenyl)theophylline","8-(4-sulfophenyl)theophylline","C031433",0,0,0,1,0]
["8-(p-tolyl)-2H-pyridazino(3,4,5-de)quinazolin-3(9H)-one","8-(p-tolyl)-2H-pyridazino(3,4,5-de)quinazolin-3(9H)-one","C000604941",1,0,0,0,0]
["8-aminoguanine","8-aminoguanine","C033495",0,0,0,6,0]
["8-bromoguanine","8-bromoguanine","C502319",1,0,0,0,0]
["8-chlorotheophylline","8-chlorotheophylline","C030093",0,0,0,1,0]
["8-hydroxyguanine","8-hydroxyguanine","C024829",33,2,0,1,0]
["8-methylpterin","8-methylpterin","C080386",2,0,0,0,0]
["8-oxo-3-thiomorpholin-4-yl-8H-acenaphtho(1,2-b)pyrrole-9-carbonitrile","8-oxo-3-thiomorpholin-4-yl-8H-acenaphtho(1,2-b)pyrrole-9-carbonitrile","C557101",1,0,0,0,0]
["9-(2-chlorobenzyl)-9H-carbazole-3-carbaldehyde","9-(2-chlorobenzyl)-9H-carbazole-3-carbaldehyde","C499102",1,0,0,0,0]
["9-(3-(3,5-dimethyl-4-(3-phenylpropyl)-1-piperazinyl)propyl)carbazole","9-(3-(3,5-dimethyl-4-(3-phenylpropyl)-1-piperazinyl)propyl)carbazole","C400074",1,0,0,0,0]
["9-(dicyanovinyl)julolidine","9-(dicyanovinyl)julolidine","C061441",1,0,0,0,0]
["9,13-retinoic acid","9,13-retinoic acid","C105492",0,1,0,0,0]
["9-amino-alpha-noscapine","9-amino-alpha-noscapine","C561203",2,0,0,0,0]
["9-azido-5,6-dihydro-11-ethyl-6-methyl-11H-pyrido(2,3-b)(1,5)benzodiazepin-5-enone","9-azido-5,6-dihydro-11-ethyl-6-methyl-11H-pyrido(2,3-b)(1,5)benzodiazepin-5-enone","C092891",1,0,0,0,0]
["9-cis-retinal","9-cis-retinal","C031390",2,0,0,0,0]
["9-deoxy-9-chloro-15-deoxy-16-hydroxy-17,17-trimethylene-19,20-didehydroprostaglandin E2","9-deoxy-9-chloro-15-deoxy-16-hydroxy-17,17-trimethylene-19,20-didehydroprostaglandin E2","C499423",0,0,0,3,0]
["9H-purine-9-propanamine, 6-amino-8-((6-iodo-1,3-benzodioxol-5-yl)thio)-N-(1-methylethyl)-","9H-purine-9-propanamine, 6-amino-8-((6-iodo-1,3-benzodioxol-5-yl)thio)-N-(1-methylethyl)-","C526550",1,0,0,0,0]
["9-hydroxystearic acid","9-hydroxystearic acid","C070375",1,0,0,0,0]
["9-methylanthracene","9-methylanthracene","C046962",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8324,B8324)","v":"A 285222"},"A 285222","C494244",0,0,0,3,0]
["A 769662","A 769662","C512408",2,0,0,0,0]
["A-102395","A-102395","C527229",1,0,0,0,0]
["A-841720","A-841720","C516995",2,0,0,0,0]
["ABT-100","ABT-100","C503142",0,0,0,1,0]
["acarviostatin III0(-1)","acarviostatin III0(-1)","C583432",1,0,0,0,0]
["acefylline","acefylline","C019140",0,3,0,0,0]
["acetaminophen sulfate ester","acetaminophen sulfate ester","C045667",1,0,0,0,0]
["acetyl 4-aminosalicylic acid","acetyl 4-aminosalicylic acid","C086759",1,0,0,0,0]
["acetyl phosphate","acetyl phosphate","C011632",5,0,0,0,0]
["acetylpodocarpic dimer","acetylpodocarpic dimer","C452852",1,0,0,0,0]
["acridine half-mustard","acridine half-mustard","C004294",0,0,0,4,0]
["acridone","acridone","C041300",1,0,0,0,0]
["actinorhodin","actinorhodin","C013390",1,0,0,0,0]
["adamantyl-globotriaosyl ceramide","adamantyl-globotriaosyl ceramide","C514155",2,0,0,0,0]
["adefovir dipivoxil","adefovir dipivoxil","C106812",2,0,0,6,0]
["adjuvant SBAS-2","adjuvant SBAS-2","C472719",0,0,0,4,0]
["aeroplysinin I","aeroplysinin I","C042151",1,0,0,0,0]
["aflatoxin B1-2,3-oxide","aflatoxin B1-2,3-oxide","C006426",1,0,0,0,0]
["AG 127","AG 127","C069028",0,0,0,1,0]
["agelasine D","agelasine D","C509934",1,0,0,0,0]
["agelenin","agelenin","C077703",1,0,0,0,0]
["agnuside","agnuside","C452960",0,0,0,6,0]
["AIF extract","AIF extract","C504991",0,0,0,3,0]
["AL 3152","AL 3152","C076003",1,0,0,0,0]
["alboaggregin A","alboaggregin A","C112003",1,0,0,0,0]
["Alexa Fluor 647","Alexa Fluor 647","C569686",3,0,0,0,0]
["alhagidin","alhagidin","C120120",0,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8516,B8516)","v":"alizarin"},"alizarin","C010078",1,0,0,1,0]
["ALLO 7","ALLO 7","C104268",0,0,0,1,0]
["allose","allose","C002055",1,0,3,6,0]
["almorexant","almorexant","C519150",1,0,0,0,0]
["alpha-(2,4-dimethylphenylethyl-2-oxo)indole-3-acetic acid","alpha-(2,4-dimethylphenylethyl-2-oxo)indole-3-acetic acid","C574629",2,0,0,0,0]
["alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid","alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid","D018350",23,0,0,0,0]
["alpha-conotoxin ImI","alpha-conotoxin ImI","C087686",7,0,0,0,0]
["alpha-cyano-(3,4-dihydroxy)-N-(3-phenylpropyl)cinnamide","alpha-cyano-(3,4-dihydroxy)-N-(3-phenylpropyl)cinnamide","C095713",0,6,0,0,0]
["alpha-hexachlorocyclohexane","alpha-hexachlorocyclohexane","C040534",1,0,0,0,0]
["alpha-keto-beta-methylvaleric acid","alpha-keto-beta-methylvaleric acid","C016211",1,0,0,0,0]
["alpha-S-galactosylceramide","alpha-S-galactosylceramide","C561494",0,0,4,0,0]
["alprogen","alprogen","C403078",0,0,1,0,0]
["altertoxin II","altertoxin II","C050234",0,0,0,1,0]
["ALVAC vaccine","ALVAC vaccine","C078788",0,0,5,13,0]
["AM 251","AM 251","C103505",4,0,0,0,0]
["amarogentin","amarogentin","C102609",1,3,0,0,0]
["americanin B","americanin B","C000598877",0,6,0,0,0]
["amidinophenylpyruvic acid","amidinophenylpyruvic acid","C006492",2,0,0,0,0]
["Aminoethylphosphonic Acid","Aminoethylphosphonic Acid","D000615",2,0,0,0,0]
["Aminooxyacetic Acid","Aminooxyacetic Acid","D000625",2,0,0,0,0]
["ammodytoxin A","ammodytoxin A","C068117",6,0,0,0,0]
["ammonium trichloro(dioxoethylene-O,O'-)tellurate","ammonium trichloro(dioxoethylene-O,O'-)tellurate","C054105",0,6,0,23,0]
["amphotericin B-arabinogalactan conjugate","amphotericin B-arabinogalactan conjugate","C492445",0,0,0,3,0]
["Amylose","Amylose","D000688",11,0,0,0,0]
["anacardic acid","anacardic acid","C088115",5,0,0,0,0]
["Anethole Trithione","Anethole Trithione","D000781",0,0,0,2,0]
["aniracetam","aniracetam","C036466",1,0,0,0,0]
["anpirtoline","anpirtoline","C075631",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8708,B8708)","v":"anthrax toxin"},"anthrax toxin","C030325",113,3,45,57,0]
["anti-epilepsy peptide, Buthrus martensii","anti-epilepsy peptide, Buthrus martensii","C058792",2,0,0,0,0]
["antigen G250","antigen G250","C400566",0,0,3,1,0]
["antigen Sm10, Schistosoma","antigen Sm10, Schistosoma","C106491",0,0,0,1,0]
["antofine","antofine","C473343",1,0,0,0,0]
["aplysqualenol A","aplysqualenol A","C578578",1,0,0,0,0]
["apogossypol","apogossypol","C492806",1,0,0,0,0]
["apricoxib","apricoxib","C514354",1,0,0,0,0]
["araban","araban","C030080",4,0,0,1,0]
["arabilin","arabilin","C553367",1,0,0,0,0]
["arachidonyl-2-chloroethylamide","arachidonyl-2-chloroethylamide","C119325",1,0,0,0,0]
["arcaine","arcaine","C006624",1,0,0,0,0]
["archazolid A","archazolid A","C519727",1,0,0,0,0]
["aristolochic acid II","aristolochic acid II","C042310",2,0,0,0,0]
["ARRY-403","ARRY-403","C000611842",1,0,0,0,0]
["arsenic trichloride","arsenic trichloride","C050510",1,0,0,0,0]
["Arteparon","Arteparon","C010034",0,0,0,3,0]
["AS01B adjuvant","AS01B adjuvant","C000616023",0,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8836,B8836)","v":"ascochlorin"},"ascochlorin","C415745",2,0,0,0,0]
["asoprisnil","asoprisnil","C488516",1,0,0,0,0]
["ASTM F-75 implant alloy","ASTM F-75 implant alloy","C105750",1,0,0,0,0]
["asunaprevir","asunaprevir","C571889",1,0,0,3,0]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445",4,0,0,0,0]
["atrasentan","atrasentan","C098644",2,0,0,0,0]
["auriculasin","auriculasin","C516713",1,0,0,0,0]
["avarone","avarone","C046374",0,0,0,3,0]
["Avemar","Avemar","C113915",0,0,0,1,0]
["AWD 12-281","AWD 12-281","C470045",0,0,0,0,0]
["AZ4800","AZ4800","C572499",1,0,0,0,0]
["azalactone ferrocene","azalactone ferrocene","C502556",1,0,0,0,0]
["AZD 1480","AZD 1480","C545606",2,0,3,6,0]
["AZD4694","AZD4694","C552498",1,0,0,0,0]
["azidopine","azidopine","C041130",1,0,0,0,0]
["azimilide","azimilide","C086123",1,0,0,0,0]
["azumolene","azumolene","C061387",1,0,0,0,0]
["bacteriochlorin a","bacteriochlorin a","C065423",1,0,0,0,0]
["baicilein","baicilein","C413305",2,0,0,0,0]
["BAM-SiPc","BAM-SiPc","C516359",0,0,3,0,0]
["Basic Red 51","Basic Red 51","C000589147",0,3,0,0,0]
["batanopride","batanopride","C060190",1,0,0,0,0]
["BAY 58-2667","BAY 58-2667","C480588",2,0,0,0,0]
["BB3497","BB3497","C425109",2,0,0,0,0]
["BBR3378","BBR3378","C569470",0,0,0,3,0]
["bekanamycin","bekanamycin","C001495",3,0,0,0,0]
["belinostat","belinostat","C487081",2,0,0,0,0]
["Bencyclane","Bencyclane","D001537",2,0,0,0,0]
["benzaldehyde","benzaldehyde","C032175",4,0,0,0,0]
["benzanthracene-8,9-oxide","benzanthracene-8,9-oxide","C035084",1,0,0,0,0]
["benzenesulfonamide","benzenesulfonamide","C038198",27,0,0,0,0]
["benzo(b)-2,3-dihydrofuran-2-one","benzo(b)-2,3-dihydrofuran-2-one","C464974",2,0,0,0,0]
["benzofuran","benzofuran","C105430",8,0,0,0,0]
["benzovesamicol","benzovesamicol","C502757",2,0,0,0,0]
["benzyl-alpha-N-acetylgalactosamine","benzyl-alpha-N-acetylgalactosamine","C080739",1,0,0,0,0]
["benzyldithiocarbamic acid","benzyldithiocarbamic acid","C550532",1,0,0,0,0]
["benzylsuccinate","benzylsuccinate","C030196",1,0,0,0,0]
["beta-apo-8'-carotenal","beta-apo-8'-carotenal","C110652",1,0,0,0,0]
["beta-carboline-3-carboxylic acid ethyl ester","beta-carboline-3-carboxylic acid ethyl ester","C024915",2,0,0,0,0]
["beta-hydroxyvaleric acid","beta-hydroxyvaleric acid","C013056",0,1,0,0,0]
["beta-peltatin A methyl ether","beta-peltatin A methyl ether","C010499",1,0,0,0,0]
["beta-phosphonopropionic acid","beta-phosphonopropionic acid","C003128",1,0,0,0,0]
["BGB-283","BGB-283","C000609386",1,0,0,0,0]
["BIBR 953","BIBR 953","C453961",1,0,0,0,0]
["BIBW 22","BIBW 22","C080982",2,0,0,0,0]
["bicyclo(3.1.0)hexane","bicyclo(3.1.0)hexane","C046059",1,0,0,0,0]
["BINOL, naphthol","BINOL, naphthol","C406944",1,0,0,0,0]
["bionole","bionole","C089797",0,0,0,6,0]
["biotinyl N-hydroxysuccinimide ester","biotinyl N-hydroxysuccinimide ester","C033788",4,0,2,0,0]
["biotinyltyramide","biotinyltyramide","C111551",1,0,1,0,0]
["bis(2-(4-phosphonooxyphenoxy)carbonylethyl)phosphinic acid","bis(2-(4-phosphonooxyphenoxy)carbonylethyl)phosphinic acid","C494555",1,0,0,0,0]
["bis(3',3''-diiodo-4',4''-dihydroxy-5',5''-dinitrophenyl)-3,4,5,6-tetrabromosulfonphthalein","bis(3',3''-diiodo-4',4''-dihydroxy-5',5''-dinitrophenyl)-3,4,5,6-tetrabromosulfonphthalein","C121955",1,0,0,0,0]
["bis(bipyridyl)ruthenium(II)","bis(bipyridyl)ruthenium(II)","C103599",3,0,0,0,0]
["bis(p-chlorophenyl)acetic acid","bis(p-chlorophenyl)acetic acid","C000849",1,0,0,0,0]
["bis-acridine","bis-acridine","C484811",3,0,0,0,0]
["bisgerayafoline D","bisgerayafoline D","C000593499",1,0,0,0,0]
["bisnorbiotin","bisnorbiotin","C002143",1,0,0,0,0]
["BIX 02189","BIX 02189","C533207",1,0,0,0,0]
["Bla g 6 allergen, Blattella germanica","Bla g 6 allergen, Blattella germanica","C511810",2,0,0,0,0]
["blood group B trisaccharide","blood group B trisaccharide","C406478",1,0,0,0,0]
["BM 113","BM 113","C121324",1,0,0,0,0]
["BMS 200150","BMS 200150","C101970",1,0,0,0,0]
["BMS-247243","BMS-247243","C452864",1,0,0,0,0]
["BMS-626529","BMS-626529","C584152",1,0,0,3,0]
["BMY 33004","BMY 33004","C083528",1,0,0,0,0]
["bolaamphiphile","bolaamphiphile","C543575",1,0,0,0,0]
["bolinaquinone","bolinaquinone","C500927",2,0,0,0,0]
["bornaprolol","bornaprolol","C018417",1,0,0,0,0]
["botrocetin","botrocetin","C030961",13,0,0,0,0]
["brasilicardin A","brasilicardin A","C118259",0,0,0,3,0]
["bretazenil","bretazenil","C054626",2,0,0,0,0]
["breviscapine","breviscapine","C061097",1,0,0,0,0]
["BRL 15572","BRL 15572","C108532",1,0,0,0,0]
["Bromcresol Green","Bromcresol Green","D001961",8,0,0,0,0]
["bromobenzene 2,3-oxide","bromobenzene 2,3-oxide","C043066",2,0,0,0,0]
["bromotriethylstannane","bromotriethylstannane","C026405",2,0,0,0,0]
["Brompheniramine","Brompheniramine","D001977",2,0,0,0,0]
["BTG 502","BTG 502","C060813",1,0,0,0,0]
["bufadienolide","bufadienolide","C087925",0,0,0,3,0]
["bufuralol","bufuralol","C010831",1,0,0,0,0]
["bu-shen-ning-xin","bu-shen-ning-xin","C000607029",0,0,0,3,0]
["Butylhydroxybutylnitrosamine","Butylhydroxybutylnitrosamine","D002085",0,0,0,4,0]
["butylidenephthalide","butylidenephthalide","C026105",0,0,3,0,0]
["C 1311","C 1311","C098965",1,0,0,0,0]
["CA215 antigen, human","CA215 antigen, human","C541379",1,0,0,0,0]
["CA-72-4 antigen","CA-72-4 antigen","C083825",0,0,0,1,0]
["cadralazine","cadralazine","C031877",1,0,0,0,0]
["calcium fructoborate","calcium fructoborate","C507177",0,3,0,0,0]
["calcium phosphate, dibasic, anhydrous","calcium phosphate, dibasic, anhydrous","C485829",7,0,0,0,0]
["callyspongidiol","callyspongidiol","C548229",0,0,6,3,0]
["campesterol","campesterol","C021273",0,0,0,3,0]
["camphorquinone","camphorquinone","C553149",0,9,0,0,0]
["canventol","canventol","C082453",0,0,0,1,0]
["caramiphen","caramiphen","C004519",1,0,0,0,0]
["carboapatite","carboapatite","C030782",2,0,1,0,0]
["carboprostacyclin","carboprostacyclin","C026678",1,0,0,0,0]
["carboxymethyl dextran","carboxymethyl dextran","C014392",6,0,0,1,0]
["carboxytolbutamide","carboxytolbutamide","C006913",1,0,0,0,0]
["carpropamid","carpropamid","C113565",1,0,0,0,0]
["casticin","casticin","C054133",0,0,0,6,0]
["cathinone","cathinone","C023665",2,0,0,3,0]
["CBLC137","CBLC137","C000600493",2,0,0,0,0]
["CC 3052","CC 3052","C115112",0,0,0,9,0]
["CD 437","CD 437","C099555",2,7,0,9,0]
["CD320 antigen, human","CD320 antigen, human","C538894",1,0,0,0,0]
["CD532 compound","CD532 compound","C000592902",1,0,0,0,0]
["CD96 antigen","CD96 antigen","C116131",3,0,0,3,0]
["CDRI-97-78","CDRI-97-78","C574493",0,3,0,0,0]
["cefcanel","cefcanel","C022605",1,0,0,0,0]
["ceforanide","ceforanide","C012653",2,0,0,0,0]
["cefpodoxime proxetil","cefpodoxime proxetil","C053267",4,0,0,0,0]
["cefuzonam","cefuzonam","C049934",2,0,0,0,0]
["cellulose acetate 1,2-benzenedicarboxylate","cellulose acetate 1,2-benzenedicarboxylate","C496530",0,0,0,1,0]
["centaureidin","centaureidin","C083161",2,0,0,3,0]
["Cephacetrile","Cephacetrile","D002505",3,0,0,0,0]
["cephalosporin C","cephalosporin C","C025163",2,0,0,0,0]
["cerebroside sulfate","cerebroside sulfate","C083015",1,0,0,3,0]
["cetiedil","cetiedil","C006955",1,0,0,0,0]
["CFM6104","CFM6104","C586919",0,0,0,3,0]
["CGP 56999A","CGP 56999A","C102659",1,0,0,0,0]
["CGS 27023A","CGS 27023A","C097658",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C9668,B9668)","v":"chamaejasmine"},"chamaejasmine","C511440",1,0,0,0,0]
["chelerythrine","chelerythrine","C016299",11,0,0,5,0]
["ChimeriVax","ChimeriVax","C445780",0,0,0,1,0]
["chitotriose","chitotriose","C041161",3,0,0,0,0]
["Chloranil","Chloranil","D002703",3,0,0,0,0]
["Chlorisondamine","Chlorisondamine","D002714",1,0,0,3,0]
["chlorodiethylenetriamine platinum","chlorodiethylenetriamine platinum","C032799",2,0,0,0,0]
["Chlorotrianisene","Chlorotrianisene","D002741",1,0,0,0,0]
["chlorowax 500C","chlorowax 500C","C010555",1,0,0,0,0]
["Chlorzoxazone","Chlorzoxazone","D002753",9,0,0,0,0]
["cholesteryl oleate","cholesteryl oleate","C014409",3,0,0,0,0]
["cholesterylamine","cholesterylamine","C072855",0,0,0,2,0]
["chrome azurol S","chrome azurol S","C015076",1,0,0,0,0]
["chrysoidine","chrysoidine","C005562",3,0,0,0,0]
["CI 972","CI 972","C070377",0,0,0,13,0]
["CID 56642816","CID 56642816","C587714",1,0,0,0,0]
["Cimbi-36","Cimbi-36","C586246",2,0,0,0,0]
["cimetidine sulfoxide","cimetidine sulfoxide","C034042",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C9796,B9796)","v":"cinobufagin"},"cinobufagin","C002471",1,0,3,0,0]
["cis-6-oxo-hexahydropyrrolo(3,2-c)pyrazole","cis-6-oxo-hexahydropyrrolo(3,2-c)pyrazole","C501619",2,0,0,0,0]
["citronellal","citronellal","C108217",1,0,0,0,0]
["cladosporol B","cladosporol B","C000610717",1,0,0,0,0]
["clebopride","clebopride","C014417",1,0,0,0,0]
["cleomiscosin C","cleomiscosin C","C438427",1,0,0,0,0]
["clofilium","clofilium","C022799",1,0,0,0,0]
["Clostridium perfringens toxoid","Clostridium perfringens toxoid","C035454",0,0,0,3,0]
["CMDBS 25","CMDBS 25","C099253",2,0,0,0,0]
["Coal Ash","Coal Ash","D060729",1,3,1,3,0]
["cobamamide","cobamamide","C000913",32,0,0,0,0]
["cochinchinenin","cochinchinenin","C475447",1,0,0,0,0]
["colchicide","colchicide","C111968",1,0,0,0,0]
["collemin A","collemin A","C483008",0,3,0,0,0]
["combretastatin","combretastatin","C040105",9,0,0,3,0]
["compound 50F10","compound 50F10","C000591751",1,0,0,0,0]
["concanamycin B","concanamycin B","C036979",0,0,3,3,0]
["conotoxin GIII","conotoxin GIII","C046101",10,0,0,0,0]
["conotoxin TVIIA","conotoxin TVIIA","C413603",1,0,0,0,0]
["copper(I)-thiolate","copper(I)-thiolate","C048402",1,0,0,0,0]
["coralyne","coralyne","C000666",3,3,0,0,0]
["core endotoxin","core endotoxin","C042058",1,0,0,0,0]
["cortivazol","cortivazol","C005924",1,0,0,4,0]
["cotylenin A","cotylenin A","C423222",3,0,0,0,0]
["CP 123369","CP 123369","C097667",0,0,0,3,0]
["CP8863","CP8863","C465309",2,0,0,0,0]
["crambescidin 359","crambescidin 359","C449038",1,0,0,0,0]
["cRGD-LHT7","cRGD-LHT7","C580867",1,0,0,0,0]
["cryptand","cryptand","C444241",1,0,0,0,0]
["CS 0777","CS 0777","C569297",1,0,0,12,0]
["cucurbit(8)uril","cucurbit(8)uril","C507198",3,0,0,0,0]
["cucurbituril","cucurbituril","C513894",4,0,0,0,0]
["curcumenone","curcumenone","C582256",1,0,0,0,0]
["cyacrin","cyacrin","C007166",0,0,1,0,0]
["cyanidin-3-O-beta-glucopyranoside","cyanidin-3-O-beta-glucopyranoside","C462279",0,3,0,6,0]
["cyanopindolol","cyanopindolol","C047975",5,0,0,2,0]
["cycloalternan","cycloalternan","C488014",1,0,0,0,0]
["cyclobilirubin","cyclobilirubin","C041079",1,0,0,0,0]
["cyclohexyl methylphosphonofluoridate","cyclohexyl methylphosphonofluoridate","C053914",1,0,0,0,0]
["cycloplatam","cycloplatam","C055928",1,0,0,3,0]
["cycloprodigiosin","cycloprodigiosin","C108328",0,0,0,12,0]
["cyclopropylcarbinol","cyclopropylcarbinol","C490695",1,0,0,0,0]
["cystamine-sepharose","cystamine-sepharose","C034391",1,0,0,0,0]
["cytisine","cytisine","C004712",12,0,0,3,0]
["DA 7157","DA 7157","C515039",1,0,0,0,0]
["daidzin","daidzin","C013908",1,3,0,0,0]
["damavaricin Fc pentyl ether","damavaricin Fc pentyl ether","C059809",0,0,0,3,0]
["dansylpropranolol","dansylpropranolol","C038695",1,0,0,0,0]
["darbufelone","darbufelone","C109268",2,0,0,0,0]
["darodipine","darodipine","C034600",2,0,0,0,0]
["DCB 3503","DCB 3503","C509364",0,0,1,0,0]
["deacetoxyvinzolidine","deacetoxyvinzolidine","C107832",3,0,0,0,0]
["DEAE-Dextran","DEAE-Dextran","D003637",1,0,0,1,0]
["decanoyl acetaldehyde","decanoyl acetaldehyde","C023969",1,0,0,0,0]
["defoslimod","defoslimod","C400105",0,0,6,0,0]
["dehydroevodiamine","dehydroevodiamine","C028633",1,0,0,0,0]
["dehydroluciferin","dehydroluciferin","C107793",1,0,0,0,0]
["delta-palutoxin IT2, Paracoelotes lunctuosus","delta-palutoxin IT2, Paracoelotes lunctuosus","C500898",1,0,0,0,0]
["dendronobiloside A","dendronobiloside A","C438414",0,0,0,3,0]
["deoxygedunin","deoxygedunin","C000610188",1,0,0,0,0]
["dephostatin","dephostatin","C084037",0,0,0,1,0]
["desacetylcefotaxime","desacetylcefotaxime","C029281",6,0,0,0,0]
["desethylprocainamide","desethylprocainamide","C028493",2,0,0,0,0]
["desintegron O","desintegron O","C066010",0,0,0,3,0]
["desmethylsertraline","desmethylsertraline","C065162",1,0,0,0,0]
["desoxyepothilone B","desoxyepothilone B","C114026",4,0,0,0,0]
["dexamethasone 17-valerate","dexamethasone 17-valerate","C030949",0,0,0,0,0]
["dextrin 2-sulfate","dextrin 2-sulfate","C091377",0,0,0,3,0]
["DHM 32-550","DHM 32-550","C043481",1,0,0,0,0]
["diacetyldichlorofluorescein","diacetyldichlorofluorescein","C029569",2,0,0,0,0]
["diamminediaqua platinum(II)","diamminediaqua platinum(II)","C034297",1,0,0,3,0]
["diarylpropionitrile","diarylpropionitrile","C492519",2,0,0,3,0]
["diazocyclohexadienoylpropyltrimethylammonium","diazocyclohexadienoylpropyltrimethylammonium","C119727",1,0,0,0,0]
["dibenzo(aj)anthracene","dibenzo(aj)anthracene","C041515",0,2,0,0,0]
["dibromosulphthalein","dibromosulphthalein","C012479",5,0,0,0,0]
["dicetylphosphate","dicetylphosphate","C002290",4,0,0,0,0]
["dichloro(butylamine)(isopropylamine)platinum(II)","dichloro(butylamine)(isopropylamine)platinum(II)","C122085",0,3,0,0,0]
["dictamnine","dictamnine","C026398",0,3,0,0,0]
["dictyostatin","dictyostatin","C470814",1,0,0,0,0]
["dienelactone","dienelactone","C084081",1,0,0,0,0]
["diethylenetriaminepenta(methylenephosphonic) acid","diethylenetriaminepenta(methylenephosphonic) acid","C042719",1,0,0,0,0]
["diffractaic acid","diffractaic acid","C093528",0,3,0,0,0]
["Digoxigenin","Digoxigenin","D004076",7,0,2,1,0]
["dihydrocapsaicin","dihydrocapsaicin","C012906",1,0,0,3,0]
["dihydro-DIDS","dihydro-DIDS","C018564",12,0,0,1,0]
["dihydrolipoamide","dihydrolipoamide","C007409",2,0,0,0,0]
["Dihydrostreptomycin Sulfate","Dihydrostreptomycin Sulfate","D004096",8,0,0,3,0]
["dihydroxyethyldithiocarbamate","dihydroxyethyldithiocarbamate","C039353",1,0,0,0,0]
["Dilazep","Dilazep","D004109",1,0,0,0,0]
["dimethyl sulfide","dimethyl sulfide","C004784",3,0,0,0,0]
["dimethyl(2-hydroxy-5-nitrobenzyl)sulfonium","dimethyl(2-hydroxy-5-nitrobenzyl)sulfonium","C024586",1,0,0,0,0]
["dimethylmyleran","dimethylmyleran","C002037",0,0,0,1,0]
["dimyristoylphosphatidylserine","dimyristoylphosphatidylserine","C042859",2,0,0,0,0]
["di-N-acetylglucosamine","di-N-acetylglucosamine","C411704",1,0,0,0,0]
["dioleoyl phosphatidylethanolamine","dioleoyl phosphatidylethanolamine","C094877",2,0,4,0,0]
["dioxinodehydroeckol","dioxinodehydroeckol","C550453",0,4,0,0,0]
["dioxiram","dioxiram","C070632",0,0,0,3,0]
["dipfluzine","dipfluzine","C065758",1,0,0,0,0]
["dipicrylamine","dipicrylamine","C011454",2,0,0,0,0]
["dipropylacetamide","dipropylacetamide","C004651",4,0,0,0,0]
["disparlure","disparlure","C001150",1,0,0,0,0]
["ditritiocorreolide","ditritiocorreolide","C118658",0,0,0,3,0]
["DK-507k","DK-507k","C480349",1,0,0,0,0]
["DMP 811","DMP 811","C085640",1,0,0,0,0]
["dodecaborate","dodecaborate","C119788",1,0,0,0,0]
["dodecyldimethylamine oxide","dodecyldimethylamine oxide","C014518",1,0,0,0,0]
["dolutegravir","dolutegravir","C562325",4,0,0,6,0]
["DORA-22","DORA-22","C581638",1,0,0,0,0]
["doxacurium","doxacurium","C049429",2,0,0,0,0]
["DP 802","DP 802","C556098",1,0,0,0,0]
["DQ 2556","DQ 2556","C050465",1,0,0,0,0]
["DSB 120","DSB 120","C089588",1,0,0,0,0]
["DU 86","DU 86","C092034",1,0,0,0,0]
["Duxon","Duxon","C011533",0,0,0,4,0]
["Dystrophin-Associated Protein Complex","Dystrophin-Associated Protein Complex","D049028",2,0,0,0,0]
["E 3330","E 3330","C075569",5,0,0,0,0]
["EAPB0503","EAPB0503","C555838",2,0,0,0,0]
["ecabet","ecabet","C061681",3,0,0,0,0]
["echinacin","echinacin","C030210",0,0,0,4,0]
["edelfosine","edelfosine","C026659",2,3,0,13,0]
["efomycine M","efomycine M","C453219",1,0,3,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C10628,B10628)","v":"elaidyl-sulfamide"},"elaidyl-sulfamide","C577145",2,0,0,0,0]
["elsinochrome A","elsinochrome A","C062775",1,0,0,0,0]
["EM703","EM703","C509870",0,0,0,1,0]
["empagliflozin","empagliflozin","C570240",1,0,0,0,0]
["Enflurane","Enflurane","D004737",7,0,0,0,0]
["enisoprost","enisoprost","C054594",0,0,0,3,0]
["enterotoxin A E-120, Staphylococcal","enterotoxin A E-120, Staphylococcal","C479099",0,0,0,1,0]
["enterotoxin, Bacillus cereus","enterotoxin, Bacillus cereus","C040792",0,0,1,0,0]
["ephedrannin B","ephedrannin B","C539087",0,3,0,0,0]
["epigallocatechin-3-O-gallate epigallocatechin dimer","epigallocatechin-3-O-gallate epigallocatechin dimer","C576796",1,0,0,0,0]
["epolactaene","epolactaene","C095351",2,0,0,0,0]
["Epstein-Barr virus early antigen diffuse component","Epstein-Barr virus early antigen diffuse component","C083204",6,0,0,1,0]
["eribulin","eribulin","C490954",3,0,0,0,0]
["eriocalyxin B","eriocalyxin B","C516552",2,0,0,0,0]
["er-xian decoction","er-xian decoction","C517980",0,0,0,1,0]
["esaprazole","esaprazole","C042123",1,0,0,0,0]
["esculentoside A","esculentoside A","C076297",0,0,0,3,0]
["etafilcon","etafilcon","C114176",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C10756,B10756)","v":"ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate"},"ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate","C000611514",1,0,0,0,0]
["ethyl 2-(4-(12-beta-artemisininoxy))phenoxylpropionate","ethyl 2-(4-(12-beta-artemisininoxy))phenoxylpropionate","C524564",0,0,0,3,0]
["ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate","ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate","C507035",3,0,0,0,0]
["Ethyl Methanesulfonate","Ethyl Methanesulfonate","D005020",8,0,0,6,0]
["ethyl oleate","ethyl oleate","C033180",2,1,0,0,0]
["ethylglyoxal bis(thiosemicarbazonato)copper(II)","ethylglyoxal bis(thiosemicarbazonato)copper(II)","C530436",1,0,0,0,0]
["ethynyltyramine","ethynyltyramine","C055429",1,0,0,0,0]
["Etimizol","Etimizol","D005042",1,0,0,3,0]
["Eudragit L100-55","Eudragit L100-55","C446821",1,0,0,0,0]
["Eupergit C","Eupergit C","C065843",3,0,0,0,0]
["evernimicin","evernimicin","C001202",2,0,0,0,0]
["F 13640","F 13640","C473959",1,0,0,0,0]
["FANG vaccine","FANG vaccine","C573235",0,0,0,1,0]
["farnesyl pyrophosphate","farnesyl pyrophosphate","C004808",13,8,0,0,0]
["FAUC 365","FAUC 365","C467223",1,0,0,0,0]
["FCE 27677","FCE 27677","C099233",1,0,0,0,0]
["fenarimol","fenarimol","C033789",1,0,0,0,0]
["ferbam","ferbam","C011251",1,0,0,0,0]
["ferric oxyhydroxide","ferric oxyhydroxide","C092844",1,0,0,0,0]
["ferroin","ferroin","C001635",1,0,0,3,0]
["FE-SA4503","FE-SA4503","C451922",2,0,0,0,0]
["FG 7142","FG 7142","C035874",0,0,0,3,0]
["FK 453","FK 453","C077100",1,0,0,0,0]
["FLASH-07a","FLASH-07a","C000600153",0,1,0,0,0]
["FLB 457","FLB 457","C065065",2,0,0,0,0]
["florbetapir","florbetapir","C545186",2,0,0,0,0]
["flubendiamide","flubendiamide","C508762",1,0,0,0,0]
["fluocinolone","fluocinolone","C035394",0,0,0,0,0]
["fluorene","fluorene","C041509",2,0,0,0,0]
["fluorescein mercuric acetate","fluorescein mercuric acetate","C001673",1,0,0,0,0]
["fluorocarazolol","fluorocarazolol","C089702",1,0,0,0,0]
["Fluorometholone","Fluorometholone","D005469",0,0,0,0,0]
["fluperlapine","fluperlapine","C041528",1,0,0,0,0]
["Flutax 2","Flutax 2","C413450",1,0,0,0,0]
["FMR antigen","FMR antigen","C030663",0,0,0,1,0]
["formylchromone","formylchromone","C502480",1,0,0,0,0]
["forsythiaside","forsythiaside","C058049",0,3,0,0,0]
["FP-TZTP","FP-TZTP","C115177",1,0,0,0,0]
["FR 901277","FR 901277","C120193",1,0,0,0,0]
["fradafiban","fradafiban","C107917",2,0,0,0,0]
["fructose-6-phosphate","fructose-6-phosphate","C027618",10,0,0,0,0]
["fucosterol","fucosterol","C015896",0,6,0,0,0]
["FuGene","FuGene","C411955",0,2,2,0,0]
["furamidine","furamidine","C033286",2,0,0,0,0]
["G 1616","G 1616","C109852",1,0,0,0,0]
["G(A1) ganglioside","G(A1) ganglioside","C011258",2,0,1,1,0]
["gabaculine","gabaculine","C012987",2,0,0,0,0]
["Galactitol","Galactitol","D004376",1,0,0,0,0]
["galactopyranosyl-(1-1)-galactopyranoside","galactopyranosyl-(1-1)-galactopyranoside","C097786",1,0,0,0,0]
["galactosucrose","galactosucrose","C081752",0,0,3,0,0]
["gallium maltolate","gallium maltolate","C512662",1,0,0,0,0]
["gallocyanine","gallocyanine","C007062",2,0,0,0,0]
["gamma-tert-butyl methotrexate","gamma-tert-butyl methotrexate","C045204",0,0,0,4,0]
["ganglioside, GD1c","ganglioside, GD1c","C072151",0,0,1,3,0]
["ganglioside, GD2","ganglioside, GD2","C019403",10,0,2,22,0]
["GAT100","GAT100","C000614838",1,0,0,0,0]
["Gd-DO3A-diph","Gd-DO3A-diph","C526379",1,0,0,0,0]
["gemfibrozil 1-O-acylglucuronide","gemfibrozil 1-O-acylglucuronide","C094370",2,0,0,0,0]
["gepsin","gepsin","C519079",0,0,3,0,0]
["GGTI 298","GGTI 298","C102521",0,0,0,2,0]
["ginsenoside B","ginsenoside B","C093162",0,0,0,1,0]
["girodazole","girodazole","C072834",1,0,0,0,0]
["GLA 27","GLA 27","C048988",0,0,3,0,0]
["GLG-V 13","GLG-V 13","C095121",1,0,0,0,0]
["globotriose","globotriose","C113460",3,0,0,0,0]
["glucopyranosyl lipid-A","glucopyranosyl lipid-A","C000608161",0,0,3,3,0]
["Glucose Solution, Hypertonic","Glucose Solution, Hypertonic","D005950",2,0,0,0,0]
["glucuronoxylan","glucuronoxylan","C038910",0,0,0,3,0]
["glutaryl-7-aminocephalosporanic acid","glutaryl-7-aminocephalosporanic acid","C081063",1,0,0,0,0]
["glycero-3-phosphoinositol 4-phosphate","glycero-3-phosphoinositol 4-phosphate","C062528",1,0,0,3,0]
["glyceryl trioleyl ether","glyceryl trioleyl ether","C035206",0,0,0,1,0]
["glycitin","glycitin","C433283",0,3,0,0,0]
["glycoprotein GP37","glycoprotein GP37","C049664",0,0,0,2,0]
["glyoxylic acid","glyoxylic acid","C031150",3,0,0,1,0]
["goedecke 6976","goedecke 6976","C459383",0,3,0,0,0]
["gonyautoxins","gonyautoxins","C013007",1,0,0,0,0]
["gp100(209-2M) vaccine","gp100(209-2M) vaccine","C544395",0,0,0,2,0]
["GR 65630","GR 65630","C059068",1,0,0,0,0]
["grayanotoxin I","grayanotoxin I","C001311",2,0,0,0,0]
["GRL-05010","GRL-05010","C000593711",0,0,0,3,0]
["GSK 1838705A","GSK 1838705A","C546191",1,0,0,0,0]
["GSK239512","GSK239512","C584220",1,0,0,0,0]
["GSQ1530","GSQ1530","C471220",1,0,0,0,0]
["guaijaverin","guaijaverin","C519462",1,0,0,0,0]
["gumisol","gumisol","C024807",0,0,0,3,0]
["GW420867X","GW420867X","C402066",3,0,0,0,0]
["GYY 4137","GYY 4137","C529376",0,3,0,0,0]
["H-2K(K) antigen","H-2K(K) antigen","C024755",25,0,17,55,0]
["halichondrin B","halichondrin B","C070519",1,0,0,0,0]
["Halofenate","Halofenate","D006218",5,0,0,0,0]
["harziphilone","harziphilone","C103033",1,0,0,0,0]
["Hematoxylin","Hematoxylin","D006416",2,0,0,0,0]
["heme 1","heme 1","C115190",1,0,0,0,0]
["heme propionate-7","heme propionate-7","C081433",1,0,0,0,0]
["heparin, N-desulfated","heparin, N-desulfated","C044153",4,0,0,3,0]
["heparin, O-desulfated","heparin, O-desulfated","C410523",3,0,0,3,0]
["hernandezine","hernandezine","C067193",0,0,0,3,0]
["hetlaxin, Heterometrus laoticus","hetlaxin, Heterometrus laoticus","C583668",1,0,0,0,0]
["hexachloro-4-xylene","hexachloro-4-xylene","C000294",0,0,0,3,0]
["hexafluoroacetone","hexafluoroacetone","C017366",2,0,0,0,0]
["Hexavac","Hexavac","C426944",0,0,0,1,0]
["Hexestrol","Hexestrol","D006589",4,0,0,3,0]
["hippuric acid","hippuric acid","C030514",7,0,1,0,0]
["histaprodifen","histaprodifen","C118994",3,0,0,0,0]
["histolyn CYL","histolyn CYL","C040196",0,0,1,0,0]
["HMW-MAA","HMW-MAA","C406542",0,0,1,9,0]
["homocamptothecin","homocamptothecin","C120029",2,0,0,0,0]
["homoisocitric acid","homoisocitric acid","C517550",1,0,0,0,0]
["hongotoxin 1","hongotoxin 1","C110392",4,0,0,0,0]
["huaier","huaier","C000621679",0,0,1,0,0]
["human papillomavirus vaccine, L1 type 16, 18","human papillomavirus vaccine, L1 type 16, 18","C510352",0,0,3,10,0]
["huwentoxin IV, Selenocosmia huwena","huwentoxin IV, Selenocosmia huwena","C470632",1,0,0,0,0]
["hydramacroside A","hydramacroside A","C407016",0,0,2,0,0]
["Hydrocodone","Hydrocodone","D006853",1,0,0,0,0]
["hydroxide ion","hydroxide ion","C031356",4,0,3,0,0]
["hydroxybenzylpindolol","hydroxybenzylpindolol","C012357",1,0,0,0,0]
["hydroxymaprotilin","hydroxymaprotilin","C027299",3,0,1,0,0]
["Hydroxypropiophenone","Hydroxypropiophenone","D006910",1,0,0,0,0]
["hyperforin trimethoxybenzoate","hyperforin trimethoxybenzoate","C455161",1,0,0,0,0]
["hypothemycin","hypothemycin","C120440",0,0,0,3,0]
["I(HSF)115 compound","I(HSF)115 compound","C000622633",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C11588,B11588)","v":"ibuprofen 2-amino-3-methylpyridine amide"},"ibuprofen 2-amino-3-methylpyridine amide","C000608609",1,0,0,0,0]
["icariin","icariin","C056599",1,6,3,9,0]
["iclaprim","iclaprim","C486448",2,0,0,0,0]
["IDRA 21","IDRA 21","C091420",1,0,0,0,0]
["ifenprodil","ifenprodil","C010739",8,0,0,0,0]
["IMA901 vaccine","IMA901 vaccine","C583867",0,0,0,5,0]
["imidazo(1,2-c)pyrimidine","imidazo(1,2-c)pyrimidine","C584266",1,0,0,0,0]
["imidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III)","imidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III)","C113661",10,0,0,1,0]
["Imiloxan","Imiloxan","C044484",2,0,0,0,0]
["immunomodulin","immunomodulin","C404023",0,0,0,1,0]
["inaperisone","inaperisone","C052425",1,0,0,0,0]
["indazolium-tetrachlorobisindazoleruthenate(III)","indazolium-tetrachlorobisindazoleruthenate(III)","C068847",1,0,0,0,0]
["indium oxine","indium oxine","C032950",0,0,3,8,0]
["indole-2-carboxylic acid","indole-2-carboxylic acid","C058980",2,0,0,0,0]
["indolepropionic acid","indolepropionic acid","C015292",1,0,0,0,0]
["indolo(3,2-b)carbazole","indolo(3,2-b)carbazole","C075954",1,0,0,0,0]
["inflachromene","inflachromene","C000594653",1,0,0,0,0]
["inositol pentaphosphate","inositol pentaphosphate","C013571",3,0,0,1,0]
["involucratoside A","involucratoside A","C000616372",1,0,0,0,0]
["Iodamide","Iodamide","D007451",1,0,0,0,0]
["iodonaphthylazide","iodonaphthylazide","C015298",2,0,0,1,0]
["Iodopyracet","Iodopyracet","D007468",7,0,0,0,0]
["iosarcol","iosarcol","C066435",1,0,0,0,0]
["IR700DX-mbc94","IR700DX-mbc94","C000593031",1,0,0,0,0]
["iralukast","iralukast","C067425",1,0,0,0,0]
["irsogladine","irsogladine","C041836",1,0,0,0,0]
["ISIR-005","ISIR-005","C000612982",2,0,0,0,0]
["islet 64k antigen","islet 64k antigen","C075362",0,0,0,1,0]
["isocamptothecin B","isocamptothecin B","C530146",0,3,0,0,0]
["isofezolac","isofezolac","C020696",2,0,0,0,0]
["isoglobotriaosylceramide","isoglobotriaosylceramide","C037097",1,0,3,0,0]
["Isomaltose","Isomaltose","D007534",2,0,1,1,0]
["isophosphamide mustard","isophosphamide mustard","C027061",2,0,0,0,0]
["Isopropyl Thiogalactoside","Isopropyl Thiogalactoside","D007544",5,0,0,0,0]
["isovitexin","isovitexin","C049772",1,0,0,0,0]
["ivorenolide A","ivorenolide A","C581291",0,0,0,3,0]
["J 104870","J 104870","C402393",1,0,0,0,0]
["jatrorrhizine","jatrorrhizine","C055785",3,0,0,0,0]
["jenisseensoside D","jenisseensoside D","C107207",0,0,0,3,0]
["JMF2-1 compound","JMF2-1 compound","C562099",0,0,0,6,0]
["JTK 303","JTK 303","C509700",5,0,0,0,0]
["juvenile hormone III","juvenile hormone III","C036585",2,0,0,0,0]
["kabiramide C","kabiramide C","C489776",1,0,0,0,0]
["kaliotoxin KTX(3)","kaliotoxin KTX(3)","C404938",1,0,0,0,0]
["Kaolin","Kaolin","D007616",1,0,0,0,0]
["KBH A42","KBH A42","C534553",2,0,0,0,0]
["KC 500","KC 500","C477388",2,0,0,0,0]
["kelletinin A","kelletinin A","C067618",0,0,0,1,0]
["Keratan Sulfate","Keratan Sulfate","D007632",16,2,4,4,0]
["KHS101","KHS101","C553183",2,0,0,0,0]
["KKD-015","KKD-015","C523232",0,0,0,3,0]
["KN 93","KN 93","C072105",0,0,0,4,0]
["kopsinidine E","kopsinidine E","C000621513",0,0,0,3,0]
["KR 62776","KR 62776","C534486",1,0,0,0,0]
["KRN 7000","KRN 7000","C103873",1,0,20,12,0]
["KT-18618","KT-18618","C000588597",1,0,0,0,0]
["kuwanon O","kuwanon O","C000603859",0,3,0,0,0]
["kyung-ok-ko","kyung-ok-ko","C000592339",0,0,0,6,0]
["L 655,708","L 655,708","C105490",1,0,0,0,0]
["L 659066","L 659066","C055732",2,0,0,0,0]
["L 692429","L 692429","C081455",1,0,0,0,0]
["L 738167","L 738167","C105929",2,0,0,0,0]
["L 745337","L 745337","C093700",1,0,0,0,0]
["L 783277","L 783277","C405053",1,0,0,0,0]
["labdane","labdane","C433017",0,0,3,0,0]
["lactosamine","lactosamine","C032233",5,3,0,0,0]
["laminaribiose","laminaribiose","C014637",1,0,0,0,0]
["lariciresinol","lariciresinol","C060282",0,0,0,3,0]
["larval toxin, Bacillus","larval toxin, Bacillus","C045759",1,0,0,0,0]
["LASSBio-579","LASSBio-579","C518328",1,0,0,0,0]
["lavendamycin","lavendamycin","C034566",1,0,0,0,0]
["lavendustin A","lavendustin A","C062898",0,6,0,0,0]
["Leakadine","Leakadine","C055240",0,0,0,6,0]
["leoligin","leoligin","C542788",1,0,0,0,0]
["leprosin A","leprosin A","C041383",0,0,0,2,0]
["leukotrophin","leukotrophin","C024817",0,0,0,1,0]
["Lewis a oligosaccharide","Lewis a oligosaccharide","C494219",3,0,2,2,0]
["Lewis Blood-Group System","Lewis Blood-Group System","D007983",31,1,22,14,0]
["LG 100182","LG 100182","C112414",0,3,0,0,0]
["LIGA 20","LIGA 20","C086919",1,0,0,0,0]
["linarin","linarin","C008282",0,0,0,3,0]
["lipid-linked oligosaccharides","lipid-linked oligosaccharides","C023023",21,2,16,7,0]
["lipopolysaccharide, E coli O55-B5","lipopolysaccharide, E coli O55-B5","C482199",0,0,0,3,0]
["lipstatin","lipstatin","C054164",1,0,0,0,0]
["Liuwei Dihuang Decoction","Liuwei Dihuang Decoction","C042579",0,1,0,1,0]
["LJP 993","LJP 993","C447679",0,0,1,0,0]
["Lmdd-MPFG vaccine","Lmdd-MPFG vaccine","C573135",0,0,1,1,0]
["LOE 908","LOE 908","C081356",1,0,0,0,0]
["lometrexol","lometrexol","C045894",2,0,0,0,0]
["longdan xiegan tang","longdan xiegan tang","C550522",0,0,0,5,0]
["lorazepam acetate","lorazepam acetate","C028245",2,0,0,0,0]
["losartan carboxylic acid","losartan carboxylic acid","C066026",3,0,0,0,0]
["LQB 118","LQB 118","C569361",0,0,0,3,0]
["LSN862","LSN862","C503644",1,0,0,0,0]
["Lucensomycin","Lucensomycin","D008155",1,0,0,0,0]
["luminacin D","luminacin D","C413565",0,3,0,0,0]
["Lurasidone Hydrochloride","Lurasidone Hydrochloride","D000069056",5,0,0,0,0]
["LY 2108491","LY 2108491","C510201",0,3,0,0,0]
["LY2812223","LY2812223","C000603803",2,0,0,0,0]
["Ly-49L antigen","Ly-49L antigen","C120113",1,0,0,0,0]
["lymphocryptovirus nuclear antigen 3B","lymphocryptovirus nuclear antigen 3B","C411724",1,0,0,0,0]
["lyoniside","lyoniside","C011015",0,0,0,2,0]
["M119 compound","M119 compound","C509953",3,0,0,0,0]
["macrophorin D","macrophorin D","C438424",0,0,0,3,0]
["MAGE-E1 antigen, human","MAGE-E1 antigen, human","C430404",0,0,1,0,0]
["malbrancheamide","malbrancheamide","C529354",1,0,0,0,0]
["maleinitriledithiolate","maleinitriledithiolate","C459462",1,0,0,0,0]
["maltopentaose","maltopentaose","C019193",7,0,0,0,0]
["mammeisin","mammeisin","C001878",1,0,0,0,0]
["manassantin B","manassantin B","C482885",2,3,0,0,0]
["Mangifera indica extract","Mangifera indica extract","C501277",0,0,0,1,0]
["mannose 6-phosphate N-acetylglucosamine ester","mannose 6-phosphate N-acetylglucosamine ester","C525558",1,0,0,0,0]
["mannosylamine","mannosylamine","C010215",1,0,0,0,0]
["mansonone E","mansonone E","C496164",2,0,0,0,0]
["matrine","matrine","C034244",4,3,3,12,0]
["maurocalcine","maurocalcine","C406406",5,0,0,0,0]
["MC 1627","MC 1627","C119704",1,0,0,0,0]
["MDL 27088","MDL 27088","C059757",1,0,0,0,0]
["MDL 27788","MDL 27788","C059758",1,0,0,0,0]
["Meclofenamic Acid","Meclofenamic Acid","D008469",5,0,0,0,0]
["meglumine iodipamide","meglumine iodipamide","C006753",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C12420,B12420)","v":"meiogynin A"},"meiogynin A","C548770",2,0,0,0,0]
["Melibiose","Melibiose","D008553",8,0,0,1,0]
["menthofuran","menthofuran","C054487",1,0,0,0,0]
["Mepartricin","Mepartricin","D008613",1,0,0,0,0]
["mer-trichloro(acrylonitrile)(dipyrido(3,2-d-2',3'-f)quinoxaline)ruthenium(III)","mer-trichloro(acrylonitrile)(dipyrido(3,2-d-2',3'-f)quinoxaline)ruthenium(III)","C528076",1,0,0,0,0]
["meso-tetrakis(4-sulfonatophenyl)porphyrin","meso-tetrakis(4-sulfonatophenyl)porphyrin","C092400",1,0,0,0,0]
["metaiodopsin II","metaiodopsin II","C086952",1,0,0,0,0]
["Metergoline","Metergoline","D008711",3,0,0,0,0]
["methanesulfonamide","methanesulfonamide","C036871",1,0,0,0,0]
["Methenolone","Methenolone","D008710",1,0,0,1,0]
["methotrexate di-n-butyl ester","methotrexate di-n-butyl ester","C022153",1,0,0,0,0]
["methoxy poly(ethylene glycol-co-epsilon-caprolactone)","methoxy poly(ethylene glycol-co-epsilon-caprolactone)","C439611",1,0,0,0,0]
["methoxytryptophol","methoxytryptophol","C002465",2,0,0,0,0]
["methyl 20-dihydroprednisolonate","methyl 20-dihydroprednisolonate","C025428",1,0,0,0,0]
["methyl 3,5-diiodo-4-(4'-methoxyphenoxy)benzoate","methyl 3,5-diiodo-4-(4'-methoxyphenoxy)benzoate","C436733",2,0,0,0,0]
["methyl 4-O-beta-glucopyranosyl-2-O-alpha-rhamnopyranosyl-beta-galactopyranoside","methyl 4-O-beta-glucopyranosyl-2-O-alpha-rhamnopyranosyl-beta-galactopyranoside","C064412",0,0,1,0,0]
["methyl beta-cellobioside","methyl beta-cellobioside","C082831",1,0,0,0,0]
["Methyl Chloride","Methyl Chloride","D008737",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C12548,B12548)","v":"methyl lactoside"},"methyl lactoside","C034207",1,0,0,0,0]
["methyl O-rhamnopyranosyl-(1-2)-4-deoxygalactopyranoside","methyl O-rhamnopyranosyl-(1-2)-4-deoxygalactopyranoside","C086573",0,0,1,0,0]
["methyl triclosan","methyl triclosan","C502486",0,3,0,0,0]
["methylene radical","methylene radical","C504223",1,0,0,0,0]
["methylhydroxybenzimidate","methylhydroxybenzimidate","C014099",0,0,0,1,0]
["methylmercury II","methylmercury II","C030957",1,0,0,0,0]
["methylphosphate","methylphosphate","C027265",2,0,0,0,0]
["methylselenic acid","methylselenic acid","C008493",2,0,0,0,0]
["metioprim","metioprim","C036263",1,0,0,0,0]
["Metrizamide","Metrizamide","D008793",7,0,0,0,0]
["MI 43 compound","MI 43 compound","C530788",2,0,0,0,0]
["michellamine A","michellamine A","C072235",0,0,0,3,0]
["midaglizole","midaglizole","C032368",1,0,0,0,0]
["minor H antigen H60","minor H antigen H60","C114735",6,0,4,20,0]
["mitochondrial antigen 36 kDa","mitochondrial antigen 36 kDa","C062489",0,0,1,0,0]
["MitoTracker Red 580","MitoTracker Red 580","C507919",0,0,0,1,0]
["MK-6096","MK-6096","C573816",2,0,0,0,0]
["MKC 231","MKC 231","C092988",2,0,0,0,0]
["ML347","ML347","C584754",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C12676,B12676)","v":"MM 11254"},"MM 11254","C418636",1,0,0,0,0]
["Moclobemide","Moclobemide","D020912",4,0,0,0,0]
["monascin","monascin","C517880",0,0,0,3,0]
["monoethylglycinexylidide","monoethylglycinexylidide","C001173",3,0,0,0,0]
["monoferrous acid citrate","monoferrous acid citrate","C016600",1,0,0,0,0]
["monomycoloyl glycerol","monomycoloyl glycerol","C543328",0,0,0,3,0]
["morpholine","morpholine","C037574",6,0,0,0,0]
["morpholinoanthracycline MX2","morpholinoanthracycline MX2","C053537",1,0,0,0,0]
["moxaprindine","moxaprindine","C023489",2,0,0,0,0]
["MS 8209","MS 8209","C074660",1,0,0,3,0]
["MSP1(42)-FVO alhydrogel vaccine","MSP1(42)-FVO alhydrogel vaccine","C527290",0,0,0,1,0]
["mucinous carcinoma-associated antigen","mucinous carcinoma-associated antigen","C057387",0,0,1,1,0]
["Murexide","Murexide","D009114",1,0,0,0,0]
["murrayafoline A","murrayafoline A","C443728",0,0,3,0,0]
["MY 12-62c","MY 12-62c","C049991",1,0,0,0,0]
["mycobactins","mycobactins","C018608",3,0,1,3,0]
["mycoside B","mycoside B","C054991",0,0,1,0,0]
["myxillin A","myxillin A","C000613992",0,0,3,0,0]
["N-((2-hydroxy-3-trimethylammonium)propyl)chitosan chloride","N-((2-hydroxy-3-trimethylammonium)propyl)chitosan chloride","C572320",0,0,0,2,0]
["N-((4-dimethylaminophenyl)methyl)-N-(4-isopropylphenyl)-7-methoxy-1,2,3,4-tetrahydronaphthalen-1-carboxamide","N-((4-dimethylaminophenyl)methyl)-N-(4-isopropylphenyl)-7-methoxy-1,2,3,4-tetrahydronaphthalen-1-carboxamide","C470794",1,0,0,0,0]
["N-(1-(3,4-difluorobenzyl)piperidin-4-yl)-6-(trifluoromethyl)pyridazin-3-amine","N-(1-(3,4-difluorobenzyl)piperidin-4-yl)-6-(trifluoromethyl)pyridazin-3-amine","C576398",1,0,0,0,0]
["N-(1,2-dihydroxylpropyl)-2,6-di-(4-methoxyphenethyl)piperidine","N-(1,2-dihydroxylpropyl)-2,6-di-(4-methoxyphenethyl)piperidine","C573789",1,0,0,0,0]
["N-(11-undecanoic acid)-N,N'-bis(2-methyl-2-mercaptopropyl)ethylenediamine","N-(11-undecanoic acid)-N,N'-bis(2-methyl-2-mercaptopropyl)ethylenediamine","C052631",1,0,0,0,0]
["N-(1-formyl-3-methylbutyl)-3-methyl-2-(4-(piperidin-1-ylazo)benzenesulfonylamino)butyramide","N-(1-formyl-3-methylbutyl)-3-methyl-2-(4-(piperidin-1-ylazo)benzenesulfonylamino)butyramide","C521971",1,0,0,0,0]
["N-(2-(((5-chloroindol-2-yl)carbonyl)amino)-5-(dimethylcarbamoyl)cyclohexyl)-5-methyl-4,5,6,7-tetrahydrothiazolo(5,4-c)pyridine-2-carboxamide","N-(2-(((5-chloroindol-2-yl)carbonyl)amino)-5-(dimethylcarbamoyl)cyclohexyl)-5-methyl-4,5,6,7-tetrahydrothiazolo(5,4-c)pyridine-2-carboxamide","C539859",1,0,0,0,0]
["N-(2-(2-(bromoacetoxy)-7-methoxynaphtyl)ethyl)-propionamide","N-(2-(2-(bromoacetoxy)-7-methoxynaphtyl)ethyl)-propionamide","C110192",1,0,0,0,0]
["N-(2-(4-amino-6,7-dimethoxy-5-pyridin-2-yl-quinazolin-2-yl)-1,2,3,4-tetrahydro-isoquinolin-5-yl)-methanesulfonamide","N-(2-(4-amino-6,7-dimethoxy-5-pyridin-2-yl-quinazolin-2-yl)-1,2,3,4-tetrahydro-isoquinolin-5-yl)-methanesulfonamide","C523956",1,0,0,0,0]
["N-(2,2,6,6-tetramethylpiperidyl-1-oxyl) N'- (cyclohexyl)carbodiimide","N-(2,2,6,6-tetramethylpiperidyl-1-oxyl) N'- (cyclohexyl)carbodiimide","C010638",1,0,0,0,0]
["N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide","N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide","C058815",3,0,0,0,0]
["N-(2-fluorophenyl)-2beta-1-deoxyfuconojirimycin acetamide","N-(2-fluorophenyl)-2beta-1-deoxyfuconojirimycin acetamide","C588116",1,0,0,0,0]
["N-(2-hydroxypropyl)-3-trimethylammonium chitosan","N-(2-hydroxypropyl)-3-trimethylammonium chitosan","C550160",0,0,0,2,0]
["N-(3-(4-azido-3-iodophenyl)propionamide)-6-aminoethylcarbamylforskolin","N-(3-(4-azido-3-iodophenyl)propionamide)-6-aminoethylcarbamylforskolin","C069863",1,0,0,0,0]
["N-(3-(6-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl)-2-methylphenyl)-4,5,6,7-tetrahydrobenzo(b)thiophene-2-carboxamide","N-(3-(6-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl)-2-methylphenyl)-4,5,6,7-tetrahydrobenzo(b)thiophene-2-carboxamide","C560621",1,0,0,0,0]
["N-(3,5-dichlorophenyl)succinimide","N-(3,5-dichlorophenyl)succinimide","C007352",1,0,0,0,0]
["N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide","N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide","C441643",1,0,0,0,0]
["N-(3-oxohexanoyl)-3-aminodihydro-2(3H)-furanone","N-(3-oxohexanoyl)-3-aminodihydro-2(3H)-furanone","C030654",1,0,0,0,0]
["N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide","N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide","C480543",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C12932,B12932)","v":"N-(4-(2-hydroxycarbamoylvinyl)benzyl)-4-pyrrolidin-1-ylbenzamide"},"N-(4-(2-hydroxycarbamoylvinyl)benzyl)-4-pyrrolidin-1-ylbenzamide","C480613",1,0,0,0,0]
["N-(4-(4-azido-3-(125I)iodophenyl)butyl)-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane","N-(4-(4-azido-3-(125I)iodophenyl)butyl)-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane","C527694",1,0,0,0,0]
["N(4)-acetylsulfamerazine","N(4)-acetylsulfamerazine","C037923",2,0,0,0,0]
["N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide","N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide","C033772",1,3,0,0,0]
["N-(4-carboxycyclohexylmethyl)maleimide N-hydroxysuccinimide ester","N-(4-carboxycyclohexylmethyl)maleimide N-hydroxysuccinimide ester","C025285",0,0,0,1,0]
["N-(4-doxorubicin-N-carbonyl(oxymethyl)phenyl)-O-glucuronyl carbamate","N-(4-doxorubicin-N-carbonyl(oxymethyl)phenyl)-O-glucuronyl carbamate","C407038",1,0,0,0,0]
["N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide","N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide","C587002",2,0,0,0,0]
["N-(4-nitrobenzyl)-N-(4-(7-phenoxyheptylpiperazin-1-yl)butyl)guanidine","N-(4-nitrobenzyl)-N-(4-(7-phenoxyheptylpiperazin-1-yl)butyl)guanidine","C576798",1,0,0,0,0]
["N-(5-(((5-tert-butyl-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-(((bis(hydroxymethyl)methyl)amino)methyl)benzeneacetamide","N-(5-(((5-tert-butyl-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-(((bis(hydroxymethyl)methyl)amino)methyl)benzeneacetamide","C465460",1,0,0,0,0]
["N-(5-fluoro-2-phenoxyphenyl)-N-(2-fluoroethyl-5-methoxybenzyl)acetamide","N-(5-fluoro-2-phenoxyphenyl)-N-(2-fluoroethyl-5-methoxybenzyl)acetamide","C475621",1,0,0,0,0]
["N(6),N(6)-dimethyladenine","N(6),N(6)-dimethyladenine","C001020",1,0,0,0,0]
["N-(6-methoxy-8-quinolyl)-4-toluenesulfonamide","N-(6-methoxy-8-quinolyl)-4-toluenesulfonamide","C061730",1,0,0,0,0]
["N-(7-nitrobenzo(c)(1,2,5)oxadiazol-4-yl)demethyltamoxifen","N-(7-nitrobenzo(c)(1,2,5)oxadiazol-4-yl)demethyltamoxifen","C000590551",1,0,0,0,0]
["N-(O-acetyl)glycoloylneuraminic acid","N-(O-acetyl)glycoloylneuraminic acid","C078888",0,0,0,1,0]
["N'-(phenyl-pyridin-2-yl-methylene)-thiophene-2-carboxylic acid hydrazide","N'-(phenyl-pyridin-2-yl-methylene)-thiophene-2-carboxylic acid hydrazide","C000595755",1,0,0,0,0]
["N,N,N',N'-tetramethyl-4,4'-methylenedianiline","N,N,N',N'-tetramethyl-4,4'-methylenedianiline","C035472",1,0,0,0,0]
["N,N'-bis(3-propionaldehyde)-1,4-diaminobutane","N,N'-bis(3-propionaldehyde)-1,4-diaminobutane","C050864",0,0,0,9,0]
["N,N'-bis(4-(1-(2-propylpiperidine)oxy)salicylidene)-4,5-methoxy-1,2-phenylenediamine Pt(II)","N,N'-bis(4-(1-(2-propylpiperidine)oxy)salicylidene)-4,5-methoxy-1,2-phenylenediamine Pt(II)","C546674",1,0,0,0,0]
["N,N'-dibenzhydrylethane-1,2-diamine dihydrochloride","N,N'-dibenzhydrylethane-1,2-diamine dihydrochloride","C507346",1,0,0,0,0]
["N,N-diisopropylethylamine","N,N-diisopropylethylamine","C027070",1,0,0,0,0]
["N,N-diisopropyltryptamine","N,N-diisopropyltryptamine","C033695",1,0,0,0,0]
["N,N-dimethylaminonapthyl-(acrylo)-nitrile","N,N-dimethylaminonapthyl-(acrylo)-nitrile","C559461",1,0,0,0,0]
["N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide","N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide","C081306",0,0,0,1,0]
["N,N'-dinitrosopiperazine","N,N'-dinitrosopiperazine","C026156",1,0,0,0,0]
["N1-((4-methoxy)methyl)-4-methyl-1,2-benzenediamine","N1-((4-methoxy)methyl)-4-methyl-1,2-benzenediamine","C000598432",0,0,6,0,0]
["N1-benzenesulfonyl-5-methoxy-N,N-dimethyltryptamine","N1-benzenesulfonyl-5-methoxy-N,N-dimethyltryptamine","C419803",1,0,0,0,0]
["N1-benzyl-4-methylbenzene-1,2-diamine","N1-benzyl-4-methylbenzene-1,2-diamine","C497734",1,0,0,0,0]
["N-4-acetyl-4-hydroxysulfamerazine","N-4-acetyl-4-hydroxysulfamerazine","C041655",1,0,0,0,0]
["N-acetyl-9-O-acetylneuraminic acid 4-aminophenylthioketoside","N-acetyl-9-O-acetylneuraminic acid 4-aminophenylthioketoside","C080093",1,0,0,0,0]
["N-acetylcochinol-O-phosphate","N-acetylcochinol-O-phosphate","C455219",1,0,0,0,0]
["N-acetylglucosamine thiazoline","N-acetylglucosamine thiazoline","C487818",4,0,0,0,0]
["N-acetylmannosamine","N-acetylmannosamine","C002022",2,0,0,0,0]
["N-acetylneuraminyl-(2-6)-galactose","N-acetylneuraminyl-(2-6)-galactose","C063866",1,0,0,0,0]
["N-acetylsulfamethoxypyridazine","N-acetylsulfamethoxypyridazine","C014952",1,0,0,0,0]
["nafamostat","nafamostat","C032855",1,0,0,5,0]
["naltrexamine, N(beta)-(Leu-Arg-Arg-Leu-Phe)-","naltrexamine, N(beta)-(Leu-Arg-Arg-Leu-Phe)-","C059551",1,0,0,0,0]
["naphthalenediimide","naphthalenediimide","C542131",1,0,0,0,0]
["naphtho(2,3-b)thiophene","naphtho(2,3-b)thiophene","C456965",0,3,0,0,0]
["narciclasine","narciclasine","C010753",1,0,0,0,0]
["NB325","NB325","C539938",0,0,0,4,0]
["N-benzoylthiourea","N-benzoylthiourea","C474261",1,0,0,0,0]
["N-biotinylphosphatidylethanolamine","N-biotinylphosphatidylethanolamine","C072348",1,0,0,0,0]
["n-butyl glycidyl ether","n-butyl glycidyl ether","C022794",0,0,0,3,0]
["N-butyrylhomoserine lactone","N-butyrylhomoserine lactone","C092312",1,1,0,1,0]
["N-carbamoylputrescine","N-carbamoylputrescine","C024563",2,0,0,0,0]
["N''-cyano-N-(6-amino-3,4-dihydro-3-hydroxy-2-methyl-2-dimethoxymethyl-2H-benzopyran-4-yl)-N'-benzylguanidine","N''-cyano-N-(6-amino-3,4-dihydro-3-hydroxy-2-methyl-2-dimethoxymethyl-2H-benzopyran-4-yl)-N'-benzylguanidine","C438686",1,0,0,0,0]
["N-cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide","N-cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide","C560085",0,0,3,0,0]
["N-desulfated,2-O,3-O-desulfated heparin","N-desulfated,2-O,3-O-desulfated heparin","C520325",2,0,0,0,0]
["NecroX-5","NecroX-5","C574766",1,0,0,0,0]
["nelotanserin","nelotanserin","C546600",1,0,0,0,0]
["neochamaejasmin B","neochamaejasmin B","C000604241",1,0,0,0,0]
["neotripterifordin","neotripterifordin","C097941",1,0,0,0,0]
["N-ethyl-4-(6-methylbenzo(d)thiazol-2-yl)aniline","N-ethyl-4-(6-methylbenzo(d)thiazol-2-yl)aniline","C000589256",2,0,0,0,0]
["netupitant","netupitant","C508854",3,0,0,0,0]
["NFAT 68","NFAT 68","C094350",0,0,0,3,0]
["N-formylanonaine","N-formylanonaine","C553481",0,3,0,0,0]
["N-hydroxy-2-(7-benzyloxy-2,3,4,5-tetrahydrobenzo(1,2,5-f)thiadiazepine-1,1-dioxide)-4-methylpentanamide","N-hydroxy-2-(7-benzyloxy-2,3,4,5-tetrahydrobenzo(1,2,5-f)thiadiazepine-1,1-dioxide)-4-methylpentanamide","C474567",1,0,0,0,0]
["N-hydroxy-N-methyl-4-(2-(4,5-dihydroxy-10-oxo-9,10-dihydroanthracene-9-yl)-2-oxoethyl)phenylacetamide","N-hydroxy-N-methyl-4-(2-(4,5-dihydroxy-10-oxo-9,10-dihydroanthracene-9-yl)-2-oxoethyl)phenylacetamide","C423349",0,3,0,0,0]
["N-hydroxysulfosuccimide","N-hydroxysulfosuccimide","C465543",1,0,0,0,0]
["nicotinamide N-oxide","nicotinamide N-oxide","C037645",1,0,0,0,0]
["nikkomycin","nikkomycin","C011952",3,0,0,0,0]
["Nimustine","Nimustine","D015376",2,0,0,2,0]
["nishindanol","nishindanol","C583772",2,3,0,0,0]
["Nitrohydroxyiodophenylacetate","Nitrohydroxyiodophenylacetate","D009592",0,0,0,3,0]
["nitrosylprotoheme","nitrosylprotoheme","C027417",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C13380,B13380)","v":"nitroxyl"},"nitroxyl","C039900",13,1,0,1,0]
["N-methyl-5-hydroxynicotinic acid","N-methyl-5-hydroxynicotinic acid","C109108",1,0,0,0,0]
["N-methylacridine","N-methylacridine","C028189",2,0,0,0,0]
["N'-methylnicotinium","N'-methylnicotinium","C070297",1,0,0,0,0]
["N-methylwelwitindolinone C nitrile","N-methylwelwitindolinone C nitrile","C092269",1,0,0,0,0]
["N-monochloro-2,2-dimethyltaurine","N-monochloro-2,2-dimethyltaurine","C573019",2,0,0,0,0]
["N-n-octylnicotinium","N-n-octylnicotinium","C507705",1,0,0,0,0]
["N-octanoyldopamine","N-octanoyldopamine","C554838",0,0,0,6,0]
["N-octanoylsphingosine-1-phosphocholine","N-octanoylsphingosine-1-phosphocholine","C096804",0,3,0,0,0]
["N-oleyl-daunorubicin","N-oleyl-daunorubicin","C000599289",1,0,0,0,0]
["norclozapine","norclozapine","C058272",8,0,0,0,0]
["Norethandrolone","Norethandrolone","D009639",3,0,0,0,0]
["norhydromorphone","norhydromorphone","C494531",1,0,0,0,0]
["norsolorinic acid","norsolorinic acid","C002754",2,0,0,0,0]
["notecarin D","notecarin D","C472032",1,0,0,0,0]
["n-pentanoic acid","n-pentanoic acid","C038780",1,0,0,0,0]
["N-propionyl-4-S-cysteaminylphenol","N-propionyl-4-S-cysteaminylphenol","C114098",1,0,1,7,0]
["N-pyrrolylpenicillin","N-pyrrolylpenicillin","C058753",1,0,0,0,0]
["NSC 295558","NSC 295558","C505448",1,0,0,0,0]
["NSC 629243","NSC 629243","C083308",1,0,0,0,0]
["NSC 74859","NSC 74859","C520337",1,0,0,0,0]
["N-succinimidyl propionate","N-succinimidyl propionate","C021749",1,0,0,0,0]
["N-tert-butyl-(2-sulfophenyl)nitrone","N-tert-butyl-(2-sulfophenyl)nitrone","C094272",0,0,0,4,0]
["nuclear fast red","nuclear fast red","C523186",1,0,0,0,0]
["N-vinylpyrrolidone-esculin copolymer","N-vinylpyrrolidone-esculin copolymer","C439589",0,0,0,1,0]
["O(6)-benzylguanine","O(6)-benzylguanine","C064976",5,0,0,4,0]
["O,S,S-trimethyl phosphorodithioate","O,S,S-trimethyl phosphorodithioate","C033125",0,0,0,3,0]
["obatoclax","obatoclax","C520962",8,0,0,0,0]
["octadeca-5,8-dienoic acid","octadeca-5,8-dienoic acid","C008695",0,1,0,0,0]
["octyl-beta-D-glucoside","octyl-beta-D-glucoside","C018619",11,0,0,0,0]
["odanacatib","odanacatib","C527128",1,0,0,4,0]
["oleanolic acid 3-acetate","oleanolic acid 3-acetate","C052658",0,0,0,1,0]
["oleylamine","oleylamine","C008703",0,0,0,2,0]
["Olmesartan Medoxomil","Olmesartan Medoxomil","D000068557",2,0,0,0,0]
["OM 89","OM 89","C050501",0,0,3,8,0]
["omega-(3-diazirinophenoxy)hexadecanoic acid","omega-(3-diazirinophenoxy)hexadecanoic acid","C029398",1,0,0,0,0]
["OMPI","OMPI","C019204",0,0,0,3,0]
["ONO4819","ONO4819","C487764",0,0,0,3,0]
["opacity proteins","opacity proteins","C050308",6,0,0,0,0]
["orantinib","orantinib","C412603",1,0,0,9,0]
["ORG 30561","ORG 30561","C090251",1,0,0,0,0]
["orobol","orobol","C059811",1,0,0,0,0]
["Ospemifene","Ospemifene","C119141",1,0,0,0,0]
["o-succinylbenzoic acid","o-succinylbenzoic acid","C013691",1,0,0,0,0]
["OX40Ig","OX40Ig","C406562",1,0,2,16,0]
["oxazofurin","oxazofurin","C065915",1,0,0,0,0]
["oxazolidine","oxazolidine","C064210",1,0,0,0,0]
["oxirene","oxirene","C012469",1,0,0,0,0]
["oxosulfonamide","oxosulfonamide","C105822",1,0,0,0,0]
["oxotremorine M","oxotremorine M","C042743",0,0,0,3,0]
["Oxymetholone","Oxymetholone","D010110",0,0,0,4,0]
["Pactamycin","Pactamycin","D010142",1,0,0,0,0]
["PADRE 45","PADRE 45","C401223",1,0,9,14,0]
["PAMAM G3.5 dendrimer","PAMAM G3.5 dendrimer","C522260",1,0,0,0,0]
["pandemrix","pandemrix","C556153",1,0,0,6,0]
["Pandinus toxin K-alpha","Pandinus toxin K-alpha","C105110",1,0,0,0,0]
["pardaxin","pardaxin","C017603",1,0,0,0,0]
["patuletin","patuletin","C079162",0,0,0,3,0]
["PB28 compound","PB28 compound","C513937",1,0,0,0,0]
["p-chloro-o-toluidine hydrochloride","p-chloro-o-toluidine hydrochloride","C556393",1,0,0,3,0]
["PD 90780","PD 90780","C096822",4,0,0,0,0]
["pectenotoxin 2","pectenotoxin 2","C098380",1,0,0,0,0]
["pelubiprofen","pelubiprofen","C040375",0,0,0,3,0]
["penicillin F","penicillin F","C067075",1,0,0,0,0]
["PENTA","PENTA","C064764",2,3,0,0,0]
["pentaethylene glycol n-octyl ether","pentaethylene glycol n-octyl ether","C489458",1,0,0,0,0]
["Pentalinonsterol","Pentalinonsterol","C000623358",0,0,0,1,0]
["PepGen P-15","PepGen P-15","C403137",1,0,0,0,0]
["perfluorodecanoic acid","perfluorodecanoic acid","C036567",2,0,0,0,0]
["perfluorosuccinic acid","perfluorosuccinic acid","C060763",1,0,0,0,0]
["peridinin","peridinin","C016040",2,0,0,0,0]
["periploside F","periploside F","C000621399",0,0,0,3,0]
["pertussis endotoxin","pertussis endotoxin","C084764",1,0,1,1,0]
["pevonedistat","pevonedistat","C539933",4,0,6,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C13892,B13892)","v":"PF 232798"},"PF 232798","C530956",1,0,0,0,0]
["Pf41 antigen, Plasmodium falciparum","Pf41 antigen, Plasmodium falciparum","C507529",2,0,0,0,0]
["Phenazocine","Phenazocine","D010620",6,0,0,0,0]
["phenolic glycolipid I, Mycobacterium leprae","phenolic glycolipid I, Mycobacterium leprae","C045169",3,0,1,6,0]
["phenstatin","phenstatin","C000612885",1,0,0,0,0]
["phenyl ether","phenyl ether","C031538",5,0,0,0,0]
["phenylacetylene","phenylacetylene","C044736",2,0,0,0,0]
["phenylglucoside","phenylglucoside","C033857",2,0,0,0,0]
["phenylisocyanide","phenylisocyanide","C019519",1,0,0,0,0]
["Phenylthiohydantoin","Phenylthiohydantoin","D010669",2,0,1,0,0]
["phillygenin","phillygenin","C542294",1,0,0,0,0]
["phorbol-12,13-diacetate","phorbol-12,13-diacetate","C008874",1,0,1,1,0]
["Phosphatidylinositol 4,5-Diphosphate","Phosphatidylinositol 4,5-Diphosphate","D019269",276,3,2,27,0]
["phosphocellulose","phosphocellulose","C008881",5,0,0,0,0]
["phosphoinositide-3,4-bisphosphate","phosphoinositide-3,4-bisphosphate","C118301",2,0,0,0,0]
["phosphonolipids","phosphonolipids","C028299",1,0,0,0,0]
["phosphorodithioic acid","phosphorodithioic acid","C083120",4,0,3,0,0]
["phthalimidine","phthalimidine","C037432",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C14020,B14020)","v":"phytoprostane F1"},"phytoprostane F1","C486066",0,0,3,0,0]
["Pi1 toxin","Pi1 toxin","C104751",2,0,0,3,0]
["picolog","picolog","C572555",0,1,0,0,0]
["pimonidazole","pimonidazole","C033815",1,0,0,0,0]
["Pimozide","Pimozide","D010868",1,0,0,0,0]
["ping-wei","ping-wei","C532898",0,0,0,6,0]
["pipequaline","pipequaline","C030078",2,0,0,0,0]
["piperonylic acid","piperonylic acid","C005455",1,0,0,0,0]
["Piribedil","Piribedil","D010891",1,0,0,0,0]
["pixantrone","pixantrone","C086548",1,0,0,9,0]
["PK 11195","PK 11195","C037850",13,0,0,5,0]
["platinum ethylenediamine dichloride","platinum ethylenediamine dichloride","C002892",1,0,0,0,0]
["pluronic block copolymer P123","pluronic block copolymer P123","C464484",1,0,0,0,0]
["pluronic block copolymer p85","pluronic block copolymer p85","C422648",1,0,0,0,0]
["pneumonococcal polysaccharide, type 4","pneumonococcal polysaccharide, type 4","C053136",0,0,1,1,0]
["Podophyllum hexandrum extract","Podophyllum hexandrum extract","C509544",1,0,0,0,0]
["poly (N-3-aminopropyl pyrrole-co-pyrrole)","poly (N-3-aminopropyl pyrrole-co-pyrrole)","C501276",1,0,0,0,0]
["poly(1,4-butylene terephthalate)","poly(1,4-butylene terephthalate)","C041733",0,1,0,0,0]
["poly(2-methyl oxazoline)-block polydimethylsiloxane-block-poly(2-methyl oxazoline)","poly(2-methyl oxazoline)-block polydimethylsiloxane-block-poly(2-methyl oxazoline)","C542789",1,0,0,0,0]
["poly(3-hydroxybutyrate-co-4-hydroxybutyrate)","poly(3-hydroxybutyrate-co-4-hydroxybutyrate)","C068056",0,1,0,0,0]
["poly(acrylamide-co-acrylic acid)","poly(acrylamide-co-acrylic acid)","C431184",1,0,0,0,0]
["poly(carbonate urea) urethane","poly(carbonate urea) urethane","C110029",1,0,0,0,0]
["poly(ethylene glycol)-b-poly(lactide-co-epsilon-caprolactone)","poly(ethylene glycol)-b-poly(lactide-co-epsilon-caprolactone)","C000613452",0,0,1,1,0]
["poly(glucosylethyl methacrylate)","poly(glucosylethyl methacrylate)","C090633",1,0,0,0,0]
["poly(hydroxyethyl methacrylate-co-styrene sulfonate)","poly(hydroxyethyl methacrylate-co-styrene sulfonate)","C571891",2,0,0,0,0]
["poly(malic acid)","poly(malic acid)","C121060",1,0,0,0,0]
["poly(n-butyl acrylate)","poly(n-butyl acrylate)","C498324",0,3,0,0,0]
["poly(N-p-vinylbenzyl-O-2-acetoamide-2-deoxyglucopyranosyl-(1-4)-2-acetoamide-2-deoxygluconamide)","poly(N-p-vinylbenzyl-O-2-acetoamide-2-deoxyglucopyranosyl-(1-4)-2-acetoamide-2-deoxygluconamide)","C000608950",0,0,1,0,0]
["poly(propylene sulfide)","poly(propylene sulfide)","C522256",0,0,1,2,0]
["poly-2-methyl-5-vinylpyridine picrate","poly-2-methyl-5-vinylpyridine picrate","C024740",0,0,0,1,0]
["poly-APS","poly-APS","C115254",3,0,0,0,0]
["polydopamine","polydopamine","C568283",1,0,3,1,0]
["polyetherurethane urea","polyetherurethane urea","C044690",4,0,0,2,0]
["polyethylene oxide-polylactic acid block copolymer","polyethylene oxide-polylactic acid block copolymer","C058523",1,0,0,0,0]
["polymannose","polymannose","C097323",1,0,0,0,0]
["poly-N-acetyl-1-6-glucosamine","poly-N-acetyl-1-6-glucosamine","C505465",1,0,0,0,0]
["polyribitol phosphate","polyribitol phosphate","C008984",0,0,0,2,0]
["polystyrene polyamine copolymer","polystyrene polyamine copolymer","C036556",0,0,0,1,0]
["polyurea","polyurea","C045786",1,0,1,3,0]
["pomiferin","pomiferin","C474837",0,3,0,0,0]
["poractant alfa","poractant alfa","C068291",1,0,0,3,0]
["potassium ferricyanide","potassium ferricyanide","C028033",1,0,0,0,0]
["PPO 464","PPO 464","C443127",1,0,0,0,0]
["precocene II","precocene II","C014163",1,0,0,0,0]
["Pregnenolone Carbonitrile","Pregnenolone Carbonitrile","D011285",4,0,0,3,0]
["pridopidine","pridopidine","C483720",6,0,0,0,0]
["PRO 2000","PRO 2000","C120231",1,0,5,6,0]
["procyanidin B","procyanidin B","C479578",0,1,0,0,0]
["procyanidin B2","procyanidin B2","C479580",3,0,0,0,0]
["Promedol","Promedol","D011396",2,0,0,0,0]
["propetamphos","propetamphos","C035967",1,0,0,0,0]
["propiconazole","propiconazole","C045950",3,0,0,0,0]
["propizepine","propizepine","C003256",1,0,0,0,0]
["Proscillaridin","Proscillaridin","D011442",1,0,0,3,0]
["prostaglandin A1","prostaglandin A1","C100573",3,0,0,6,0]
["protein antigen b, Mycobacterium","protein antigen b, Mycobacterium","C065517",0,0,0,1,0]
["protopanaxatriol","protopanaxatriol","C081552",1,3,0,0,0]
["protosappanin A","protosappanin A","C090723",0,0,1,4,0]
["PSB603","PSB603","C000592275",0,0,0,2,0]
["PSR-3-226","PSR-3-226","C574280",1,0,0,0,0]
["p-sulfonatocalix(4)arene","p-sulfonatocalix(4)arene","C511968",2,0,0,0,0]
["pulegone","pulegone","C039648",2,0,0,0,0]
["pyoluteorin","pyoluteorin","C095503",2,0,0,0,0]
["pyranine","pyranine","C005047",1,0,0,0,0]
["pyridin-2-yl hydrazine tricarbonyl-Re","pyridin-2-yl hydrazine tricarbonyl-Re","C523474",1,0,0,0,0]
["pyridoxal phosphoglucose","pyridoxal phosphoglucose","C028071",1,0,0,0,0]
["pyridoxamine phosphate","pyridoxamine phosphate","C010627",5,0,0,0,0]
["pyropheophorbide a","pyropheophorbide a","C040298",1,0,0,3,0]
["Pyrrolopyridazine","Pyrrolopyridazine","C508945",1,0,0,0,0]
["QB 90U","QB 90U","C570176",0,0,0,1,0]
["quercitrin","quercitrin","C012526",4,0,0,3,0]
["Quinacrine Mustard","Quinacrine Mustard","D011797",1,0,0,0,0]
["Quinic Acid","Quinic Acid","D011801",8,6,1,9,0]
["Quinuclidinyl Benzilate","Quinuclidinyl Benzilate","D011813",11,0,0,0,0]
["R 115866","R 115866","C406527",1,3,0,0,0]
["R 94138","R 94138","C117981",1,0,0,0,0]
["RA 25","RA 25","C119330",1,0,0,0,0]
["Raclopride","Raclopride","D020891",34,0,0,0,0]
["Raffinose","Raffinose","D011887",3,3,0,1,0]
["ramiprilat","ramiprilat","C052549",4,0,0,0,0]
["razaxaban","razaxaban","C500057",1,0,0,0,0]
["Reamberin","Reamberin","C549374",0,0,0,3,0]
["receptor macromolecular translocation inhibitor","receptor macromolecular translocation inhibitor","C027048",1,0,0,0,0]
["relcovaptan","relcovaptan","C082134",1,0,0,0,0]
["renal tubular antigen","renal tubular antigen","C035812",0,0,2,3,0]
["resorufin acetate","resorufin acetate","C105548",1,0,0,0,0]
["retinyl ascorbate","retinyl ascorbate","C504062",0,3,0,0,0]
["RFCNU","RFCNU","C015747",1,0,0,0,0]
["RG-tetradecylamine","RG-tetradecylamine","C465621",1,0,0,0,0]
["rhesus rotavirus vaccine","rhesus rotavirus vaccine","C052014",0,0,0,3,0]
["Rho(D) antigen","Rho(D) antigen","C026410",5,0,18,1,0]
["rHSP60, Klebsiella pneumoniae","rHSP60, Klebsiella pneumoniae","C508888",0,0,0,6,0]
["riboflavin 5'-phosphorothioate","riboflavin 5'-phosphorothioate","C054180",1,0,0,0,0]
["Rifabutin","Rifabutin","D017828",23,0,0,10,0]
["Ringer's ethyl pyruvate","Ringer's ethyl pyruvate","C439503",1,0,0,0,0]
["ritrosulfan","ritrosulfan","C000288",0,0,0,1,0]
["Ro 14-6113","Ro 14-6113","C072381",0,0,0,3,0]
["Ro 31-8830","Ro 31-8830","C076005",0,0,0,3,0]
["Ro 46-8443","Ro 46-8443","C099180",1,0,0,0,0]
["Ro 5-3335","Ro 5-3335","C072173",0,0,0,4,0]
["rokitamycin","rokitamycin","C033383",1,0,0,0,0]
["rolafagrel","rolafagrel","C066217",1,0,0,0,0]
["Rotenone","Rotenone","D012402",18,0,0,7,0]
["RRx-001","RRx-001","C577469",2,0,0,0,0]
["RS 0481","RS 0481","C069040",0,0,0,3,0]
["RTS,S-AS01B vaccine","RTS,S-AS01B vaccine","C526041",0,0,0,5,0]
["rubelloside A","rubelloside A","C095524",0,0,0,3,0]
["rubelloside B","rubelloside B","C095525",0,0,0,3,0]
["ruthenium bis(bipyridine)dicarboxybipyridine","ruthenium bis(bipyridine)dicarboxybipyridine","C058014",1,0,0,0,0]
["RWJ 67657","RWJ 67657","C400277",0,0,0,4,0]
["ryosidine","ryosidine","C041040",1,0,0,0,0]
["S 23906-1","S 23906-1","C436732",1,0,0,0,0]
["S002-853 compound","S002-853 compound","C555326",1,0,0,0,0]
["S-4893 compound","S-4893 compound","C568585",1,0,0,0,0]
["safranal","safranal","C087963",2,0,0,0,0]
["salicin","salicin","C005696",1,0,0,0,0]
["salicylihalamide A","salicylihalamide A","C410986",1,0,0,0,0]
["salmozan","salmozan","C029023",0,0,2,6,0]
["salphen","salphen","C545695",1,0,0,0,0]
["sanglifehrin A","sanglifehrin A","C121329",6,0,6,10,0]
["sapintoxin D","sapintoxin D","C065374",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C14852,B14852)","v":"SAR405838"},"SAR405838","C000593797",1,0,0,0,0]
["sarmentosine","sarmentosine","C082842",0,0,0,3,0]
["sazetidine-A","sazetidine-A","C514816",4,0,0,0,0]
["SB 223412","SB 223412","C106716",2,0,0,0,0]
["SB-656104-A","SB-656104-A","C475591",1,0,0,0,0]
["SC 299","SC 299","C409370",1,0,0,0,0]
["SC-66 compound","SC-66 compound","C000598518",2,0,0,0,0]
["Sch 29482","Sch 29482","C033922",2,0,0,0,0]
["SCH772984","SCH772984","C587178",1,0,0,0,0]
["sclerotiorin","sclerotiorin","C101449",1,0,0,0,0]
["scopolin","scopolin","C417572",1,0,0,0,0]
["scrovalentinoside","scrovalentinoside","C115546",0,0,0,3,0]
["SDZ PRI 053","SDZ PRI 053","C096888",1,0,0,0,0]
["secocholestra-trien-1,2,24-triol","secocholestra-trien-1,2,24-triol","C115758",0,1,0,0,0]
["selenotrisulfide","selenotrisulfide","C059755",1,3,0,0,0]
["senecionine","senecionine","C009237",1,0,0,0,0]
["Sephacryl Superfine","Sephacryl Superfine","C037239",2,0,0,0,0]
["sertindole","sertindole","C066304",3,0,0,0,0]
["setoperone","setoperone","C045359",2,0,0,0,0]
["Shenghua Decoction","Shenghua Decoction","C000590839",0,0,0,3,0]
["shosaiko-to","shosaiko-to","C461320",2,0,3,12,0]
["sialoglycolipids","sialoglycolipids","C009255",1,0,0,0,0]
["sialyl-N-acetyllactosamine","sialyl-N-acetyllactosamine","C032269",1,0,0,0,0]
["silicotungstic acid","silicotungstic acid","C021746",1,0,0,0,0]
["silver acetate","silver acetate","C103100",1,0,0,0,0]
["simvastatin acid","simvastatin acid","C063287",1,0,0,0,0]
["SJ 172550","SJ 172550","C549331",2,0,0,0,0]
["SK&F 101055","SK&F 101055","C051051",1,0,0,0,0]
["SK&F 85738","SK&F 85738","C047184",1,0,0,0,0]
["SM16 compound","SM16 compound","C528106",0,0,0,2,0]
["Sm-28 GST antigen, Schistosoma","Sm-28 GST antigen, Schistosoma","C067865",0,0,0,1,0]
["SMTP 4","SMTP 4","C117808",2,0,0,0,0]
["S-nitrosopenicillamine","S-nitrosopenicillamine","C024942",1,0,0,0,0]
["SNX 2112","SNX 2112","C534922",1,0,0,0,0]
["sodium ethoxide","sodium ethoxide","C098088",0,0,1,0,0]
["sodium thiocyanate","sodium thiocyanate","C024553",3,0,0,0,0]
["solasodine","solasodine","C012037",3,0,0,0,0]
["sorbitol 6-phosphate","sorbitol 6-phosphate","C035752",1,0,0,0,0]
["Sparteine","Sparteine","D013034",1,0,0,0,0]
["spheroidene","spheroidene","C005637",2,0,0,0,0]
["spirobramin","spirobramin","C038297",0,0,2,0,0]
["spirulan","spirulan","C102617",0,3,0,0,0]
["sporopollenin","sporopollenin","C009800",2,0,0,0,0]
["SR 121787","SR 121787","C108927",2,0,0,0,0]
["SR 48692","SR 48692","C079087",1,3,1,0,0]
["SSYA10-001","SSYA10-001","C000601132",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C15172,B15172)","v":"STA 2"},"STA 2","C037866",1,0,0,0,0]
["stage-specific embryonic antigen-3","stage-specific embryonic antigen-3","C052924",1,0,1,0,0]
["staphylococcal exotoxin 1","staphylococcal exotoxin 1","C416085",2,0,0,1,0]
["STARP antigen, Plasmodium falciparum","STARP antigen, Plasmodium falciparum","C109185",1,0,0,0,0]
["stearoyl alpha-lysolecithin","stearoyl alpha-lysolecithin","C026564",1,0,0,0,0]
["stephenanthrine","stephenanthrine","C049411",2,0,0,0,0]
["stigmatellin","stigmatellin","C041573",1,0,0,0,0]
["streptococcal protective antigen","streptococcal protective antigen","C119204",1,0,0,3,0]
["strigol","strigol","C483518",1,0,0,0,0]
["stypoldione","stypoldione","C039754",2,0,0,0,0]
["SU 9516","SU 9516","C433985",1,0,0,0,0]
["subglutinol B","subglutinol B","C551807",0,0,0,3,0]
["succinimide","succinimide","C032620",2,0,0,0,0]
["Sudan Black B","Sudan Black B","C016118",1,0,0,0,0]
["Sulbenicillin","Sulbenicillin","D013408",2,0,0,4,0]
["sulfamethomidine","sulfamethomidine","C043086",1,0,0,0,0]
["sulfated pentagalloylglucoside","sulfated pentagalloylglucoside","C579812",1,0,0,0,0]
["sulfo Lewis C","sulfo Lewis C","C113506",2,0,0,0,0]
["sulfo-Lewis(a)","sulfo-Lewis(a)","C116504",4,0,0,1,0]
["sulfonyl chloride","sulfonyl chloride","C044255",0,0,1,0,0]
["sulfosuccinimidyl 6-(biotinamido)hexanoate","sulfosuccinimidyl 6-(biotinamido)hexanoate","C061443",1,0,0,0,0]
["SUN 5555","SUN 5555","C060114",3,0,0,0,0]
["suppressive factor of allergy","suppressive factor of allergy","C023051",0,0,0,5,0]
["swertisin","swertisin","C556941",2,0,0,0,0]
["syringic acid","syringic acid","C001945",0,0,0,3,0]
["T 0632","T 0632","C103722",2,0,0,0,0]
["T3-3A1 antigen","T3-3A1 antigen","C051383",0,0,0,3,0]
["tafamidis","tafamidis","C547076",1,0,0,0,0]
["tafenoquine","tafenoquine","C055852",1,0,0,0,0]
["TAK 779","TAK 779","C119369",4,0,0,13,0]
["tamoxifen aziridine","tamoxifen aziridine","C031859",4,0,0,0,0]
["tamoxifen catechol","tamoxifen catechol","C119993",1,0,0,0,0]
["TASP0434299","TASP0434299","C000619116",1,0,0,0,0]
["tauropyrone","tauropyrone","C518135",2,0,0,0,0]
["tauroursodeoxycholic acid","tauroursodeoxycholic acid","C031655",4,3,0,0,0]
["technetium Tc 99m 1,2-dihydroxypropyl-1-phosphonic acid","technetium Tc 99m 1,2-dihydroxypropyl-1-phosphonic acid","C081031",1,0,0,0,0]
["Technetium Tc 99m Exametazime","Technetium Tc 99m Exametazime","D019690",1,0,2,5,0]
["technetium Tc 99m gluceptate","technetium Tc 99m gluceptate","C100014",1,0,0,0,0]
["tegobuvir","tegobuvir","C571890",1,0,0,0,0]
["telapristone acetate","telapristone acetate","C461063",1,0,0,0,0]
["telomestatin","telomestatin","C431888",2,0,0,0,0]
["tenofovir diphosphate","tenofovir diphosphate","C583447",0,0,0,3,0]
["terodiline","terodiline","C010637",3,0,0,0,0]
["tert-butylbicyclo-2-benzoate","tert-butylbicyclo-2-benzoate","C046308",1,0,0,0,0]
["tetra(3-N-methylpyridyl)porphine","tetra(3-N-methylpyridyl)porphine","C057459",1,0,0,0,0]
["tetrachlorogallein","tetrachlorogallein","C466630",1,0,0,0,0]
["tetrafluoroethylene","tetrafluoroethylene","C015531",1,0,0,0,0]
["tetrahydrosiphonodiol","tetrahydrosiphonodiol","C504707",0,0,1,0,0]
["tetramethyl rhodamine ethyl ester","tetramethyl rhodamine ethyl ester","C110932",0,0,0,1,0]
["tetrapentylammonium","tetrapentylammonium","C027435",0,0,1,0,0]
["Tetric EvoCeram","Tetric EvoCeram","C501891",1,0,0,0,0]
["textilinin","textilinin","C413544",1,0,0,0,0]
["thaxtomine A","thaxtomine A","C406691",1,0,0,0,0]
["Thenoyltrifluoroacetone","Thenoyltrifluoroacetone","D013804",1,0,0,0,0]
["thiazolo(3,2-a)perimidine","thiazolo(3,2-a)perimidine","C039201",1,0,0,0,0]
["thienopyridine","thienopyridine","C446540",5,0,0,0,0]
["thiobarbituric acid","thiobarbituric acid","C029684",1,0,0,0,0]
["thioglycerol","thioglycerol","C009465",1,0,0,0,0]
["Thiophanate","Thiophanate","D013875",2,0,0,0,0]
["Thiouracil","Thiouracil","D013889",10,0,0,1,0]
["thunberginol D","thunberginol D","C121620",0,0,1,0,0]
["thymosterin B","thymosterin B","C028821",0,0,0,3,0]
["Ticolubant","Ticolubant","C093304",2,0,0,0,0]
["timiperone","timiperone","C024159",1,0,0,0,0]
["tiopinac","tiopinac","C024834",1,0,0,0,0]
["tirucallane","tirucallane","C514393",0,0,3,0,0]
["TJU 103","TJU 103","C407006",0,0,0,12,0]
["TMX-202","TMX-202","C000590331",0,1,5,0,0]
["tofisopam","tofisopam","C012582",2,0,0,0,0]
["Tolerogen","Tolerogen","C029248",0,0,0,6,0]
["tongxinluo","tongxinluo","C513941",0,0,3,0,0]
["tosufloxacin","tosufloxacin","C055185",1,0,0,0,0]
["toxin II (Anemonia sulcata)","toxin II (Anemonia sulcata)","C028800",1,0,1,0,0]
["TRAM 34","TRAM 34","C411671",1,0,0,3,0]
["Traumeel S","Traumeel S","C433370",0,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C15684,B15684)","v":"traxoprodil mesylate"},"traxoprodil mesylate","C095106",1,0,0,0,0]
["triadimefon","triadimefon","C032910",2,0,0,0,0]
["trichloroacetaldehyde","trichloroacetaldehyde","C021100",0,0,0,7,0]
["trichlorobenzene","trichlorobenzene","C036720",0,0,3,0,0]
["triethyl phosphine gold","triethyl phosphine gold","C016797",2,0,0,0,0]
["TRIHER-2 peptide","TRIHER-2 peptide","C502312",0,0,1,0,0]
["trimethyl phosphine","trimethyl phosphine","C049750",2,0,0,0,0]
["tri-n-butylmethylammonium","tri-n-butylmethylammonium","C043902",1,0,0,0,0]
["triphenylphosphine","triphenylphosphine","C061896",4,0,0,0,0]
["triphenyltin","triphenyltin","C030665",1,0,0,7,0]
["tris(8-quinolinolato)gallium (III)","tris(8-quinolinolato)gallium (III)","C408502",3,0,0,0,0]
["tropic acid","tropic acid","C011377",1,0,0,0,0]
["tryptamine","tryptamine","C030820",3,0,0,0,0]
["tsugaric acid","tsugaric acid","C409622",0,3,0,0,0]
["tubulizine B","tubulizine B","C575846",1,0,0,0,0]
["tungsten carbide","tungsten carbide","C002802",0,6,0,0,0]
["tutin","tutin","C009614",1,0,0,0,0]
["Twin-Arginine-Translocation System","Twin-Arginine-Translocation System","D000069294",2,0,0,0,0]
["TX1 toxin, Heterometrus spinnifer","TX1 toxin, Heterometrus spinnifer","C109471",1,0,0,3,0]
["TX3 toxin, Buthus martensii","TX3 toxin, Buthus martensii","C418406",2,0,0,0,0]
["TXA497","TXA497","C000602146",0,1,0,0,0]
["Ty21a typhoid vaccine","Ty21a typhoid vaccine","C072772",0,0,0,9,0]
["tyloxapol","tyloxapol","C016811",1,0,0,0,0]
["Tyrode's solution","Tyrode's solution","C037692",1,0,0,0,0]
["tyrphostin 25","tyrphostin 25","C079836",1,0,0,0,0]
["tyrphostin 47","tyrphostin 47","C060152",3,5,0,3,0]
["tyrphostin A23","tyrphostin A23","C060641",3,4,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C15812,B15812)","v":"tyrphostin A46"},"tyrphostin A46","C086599",2,0,0,0,0]
["tyrphostin AG 1478","tyrphostin AG 1478","C101044",2,6,0,0,0]
["tyrphostin AG 814","tyrphostin AG 814","C095124",0,3,0,0,0]
["tyrphostin AG957","tyrphostin AG957","C104965",0,0,0,1,0]
["TZU 0460","TZU 0460","C045914",1,0,0,0,0]
["U 0126","U 0126","C113580",3,0,0,4,0]
["U 37883A","U 37883A","C082658",1,0,0,0,0]
["U 44069","U 44069","C028429",1,0,0,0,0]
["U 64273A","U 64273A","C068245",1,0,0,0,0]
["U 65556A","U 65556A","C068246",1,0,0,0,0]
["U 73343","U 73343","C074854",2,0,0,0,0]
["U 75412E","U 75412E","C069980",0,0,0,3,0]
["U 89678","U 89678","C087053",1,0,0,0,0]
["U 89843","U 89843","C097295",1,0,0,0,0]
["UA 62784","UA 62784","C535156",1,0,0,0,0]
["UAB 30","UAB 30","C112106",1,0,0,0,0]
["ubiquinol","ubiquinol","C003741",13,3,0,1,0]
["ubiquinone 6","ubiquinone 6","C032165",2,0,0,0,0]
["ubiquinone 8","ubiquinone 8","C030778",2,0,0,0,0]
["ubiquinone 9","ubiquinone 9","C030571",1,0,0,6,0]
["Ubiquinone Q1","Ubiquinone Q1","C025203",1,0,0,0,0]
["Ubiquinone Q2","Ubiquinone Q2","C025204",2,0,0,0,0]
["ubiquinone-O","ubiquinone-O","C109863",1,0,0,0,0]
["ubistatin A","ubistatin A","C492595",2,0,0,0,0]
["ubistatin B","ubistatin B","C492596",2,0,0,0,0]
["UC 781","UC 781","C100668",2,0,1,3,0]
["UC 82","UC 82","C100669",1,0,0,0,0]
["UCB 35625","UCB 35625","C413447",3,0,0,0,0]
["UCON 50-HB-5100","UCON 50-HB-5100","C078661",1,0,0,0,0]
["UCP0054278","UCP0054278","C540764",1,0,0,0,0]
["UCS15A","UCS15A","C426883",3,0,0,0,0]
["udenafil","udenafil","C419664",3,0,0,0,0]
["UDP-glucosamine","UDP-glucosamine","C026712",1,0,0,0,0]
["UF010 compound","UF010 compound","C000602704",1,0,0,0,0]
["Ufi gel","Ufi gel","C483158",0,3,0,0,0]
["UFT(R) drug","UFT(R) drug","C096910",0,0,0,1,0]
["UH 232","UH 232","C045971",2,0,0,0,0]
["UH 301","UH 301","C064282",1,0,0,0,0]
["UHRA-10","UHRA-10","C000595465",2,0,0,0,0]
["UHRA-9","UHRA-9","C000595464",2,0,0,0,0]
["UIC-94003","UIC-94003","C446340",2,0,0,0,0]
["UK 121265","UK 121265","C479414",1,0,0,0,0]
["UK 343,664","UK 343,664","C450961",2,0,0,0,0]
["UK 453,061","UK 453,061","C531151",1,0,0,0,0]
["ukrain","ukrain","C060921",1,6,0,18,0]
["ulapualide A","ulapualide A","C085516",2,0,0,0,0]
["ulimorelin","ulimorelin","C528884",1,0,0,0,0]
["ulipristal","ulipristal","C094854",2,0,0,0,0]
["ultra-high molecular weight polyethylene","ultra-high molecular weight polyethylene","C111601",2,0,1,1,0]
["uncarine E","uncarine E","C431786",0,0,0,1,0]
["uncarinic acid-C","uncarinic acid-C","C412669",0,0,3,1,0]
["undecagold","undecagold","C035797",1,0,0,0,0]
["undecanal","undecanal","C479548",2,0,0,0,0]
["undecane","undecane","C022884",3,0,0,0,0]
["undecanoic acid","undecanoic acid","C016173",1,0,0,0,0]
["undecaprenyl pyrophosphate","undecaprenyl pyrophosphate","C088139",1,0,0,0,0]
["undecylprodigiosin","undecylprodigiosin","C047347",1,0,0,0,0]
["unguinol","unguinol","C523064",1,0,0,0,0]
["Unifil LoFlo Plus","Unifil LoFlo Plus","C501418",0,0,0,3,0]
["UR-1102","UR-1102","C000609144",1,0,0,0,0]
["Uracil Mustard","Uracil Mustard","D014499",0,0,3,0,0]
["uranium dioxide","uranium dioxide","C012597",3,0,1,0,0]
["URB602","URB602","C501835",1,0,0,0,0]
["UR-DE257","UR-DE257","C000600808",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C15876,B15876)","v":"uretupamine A"},"uretupamine A","C454543",1,0,0,0,0]
["uretupamine B","uretupamine B","C454542",1,0,0,0,0]
["Urobilinogen","Urobilinogen","D014558",0,0,1,0,0]
["uroporphyrin III","uroporphyrin III","C022181",1,0,0,0,0]
["ursane","ursane","C000606873",1,0,0,0,0]
["uvaol","uvaol","C013330",1,3,0,0,0]
["uvariopsine","uvariopsine","C488565",2,0,0,0,0]
["UVB1 compound","UVB1 compound","C000604793",1,0,0,0,0]
["uxepam","uxepam","C039647",2,0,0,0,0]
["V-1 Immunitor","V-1 Immunitor","C452261",0,0,0,11,0]
["VA428","VA428","C584562",0,1,0,0,0]
["vabicaserin","vabicaserin","C556517",2,0,0,0,0]
["Vacc-4x","Vacc-4x","C494182",0,0,1,16,0]
["vaccaric acid glucopyranosyl-1-3-(xylopyranosyl-1-4)-rhamnopyranosyl-1-2-fucopyranosyl ester","vaccaric acid glucopyranosyl-1-3-(xylopyranosyl-1-4)-rhamnopyranosyl-1-2-fucopyranosyl ester","C514000",0,0,0,3,0]
["vadimezan","vadimezan","C066668",11,0,7,14,0]
["VAF347","VAF347","C509596",0,0,6,3,0]
["valerenic acid","valerenic acid","C037133",2,3,0,0,0]
["validamycin A","validamycin A","C030790",1,0,0,0,0]
["validamycins","validamycins","C003749",1,0,0,0,0]
["valmerin-19","valmerin-19","C000602447",1,0,0,0,0]
["valnoctamide","valnoctamide","C045179",3,0,0,0,0]
["valproic acid glucuronide","valproic acid glucuronide","C041285",2,0,0,0,0]
["Vam3 compound","Vam3 compound","C000598179",1,0,0,0,0]
["vanadium dioxide","vanadium dioxide","C581824",1,0,0,0,0]
["vanadium trioxide","vanadium trioxide","C543633",1,0,0,0,0]
["vanadocene dichloride","vanadocene dichloride","C030754",1,0,0,0,0]
["vandateroside I","vandateroside I","C000608334",0,3,0,0,0]
["vandateroside II","vandateroside II","C000608335",0,3,0,0,0]
["Vanilmandelic Acid","Vanilmandelic Acid","D014642",1,0,0,1,0]
["vanoxerine","vanoxerine","C043425",10,0,0,0,0]
["variant-2 scorpion toxin","variant-2 scorpion toxin","C043052",0,0,1,0,0]
["vasicine","vasicine","C019592",1,0,0,0,0]
["vatalanib","vatalanib","C404768",1,0,0,0,0]
["vaxfectin","vaxfectin","C460866",0,0,1,5,0]
["vaxigrip","vaxigrip","C478242",0,0,0,2,0]
["VB 11328","VB 11328","C095107",0,0,0,1,0]
["VB-201","VB-201","C552500",0,0,7,3,0]
["VB-703","VB-703","C000621292",0,0,1,0,0]
["VBP15 compound","VBP15 compound","C584811",0,0,0,3,0]
["VDRL antigen","VDRL antigen","C054448",1,0,0,0,0]
["velnacrine","velnacrine","C056424",3,0,0,0,0]
["venetoclax","venetoclax","C579720",4,0,4,0,0]
["Venus (composite resin)","Venus (composite resin)","C488393",1,0,0,0,0]
["VER-49009","VER-49009","C520150",2,0,0,0,0]
["VER-50589","VER-50589","C520149",2,0,0,0,0]
["veratric acid","veratric acid","C009333",0,1,0,0,0]
["Veratridine","Veratridine","D014701",2,0,0,3,0]
["veratryl alcohol","veratryl alcohol","C042197",1,0,0,0,0]
["verdin","verdin","C054069",1,0,0,0,0]
["verdoheme","verdoheme","C099547",3,0,0,0,0]
["vernakalant","vernakalant","C524581",1,0,0,0,0]
["vernolide-A","vernolide-A","C558651",0,0,0,1,0]
["verofylline","verofylline","C030126",1,0,0,0,0]
["veronicastroside","veronicastroside","C009652",0,0,0,3,0]
["verproside","verproside","C512483",2,0,0,0,0]
["verticine","verticine","C014242",0,3,0,0,0]
["vertilmicin","vertilmicin","C487733",1,0,0,0,0]
["vesamicol","vesamicol","C006189",6,0,0,0,0]
["vescalagin","vescalagin","C084709",2,0,0,0,0]
["vesnarinone","vesnarinone","C041667",6,0,0,8,0]
["VGA1155","VGA1155","C487956",2,0,0,0,0]
["Vi polysaccharide vaccine, typhoid","Vi polysaccharide vaccine, typhoid","C057664",1,0,0,1,0]
["vialinin A","vialinin A","C508745",2,0,0,0,0]
["vibralactone","vibralactone","C522315",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C15940,B15940)","v":"Vibrio cholerae WO7 toxin"},"Vibrio cholerae WO7 toxin","C420689",1,0,0,0,0]
["vibriobactin","vibriobactin","C040227",1,0,1,0,0]
["vibsanin B","vibsanin B","C000598979",1,0,0,0,0]
["vicenistatin","vicenistatin","C082785",1,0,0,0,0]
["vicriviroc","vicriviroc","C486781",1,0,0,2,0]
["victoria blue","victoria blue","C041370",1,0,0,0,0]
["vidofludimus","vidofludimus","C553728",0,0,0,3,0]
["Vilazodone Hydrochloride","Vilazodone Hydrochloride","D000069503",4,0,0,0,0]
["Vilmafix Blue A-R","Vilmafix Blue A-R","C091762",1,0,0,0,0]
["vinaxanthone","vinaxanthone","C086647",0,0,0,3,0]
["vinclozolin","vinclozolin","C025643",1,0,0,0,0]
["vindeburnol","vindeburnol","C044616",0,0,0,3,0]
["vindoline","vindoline","C009667",5,0,0,0,0]
["vinflunine","vinflunine","C111217",3,0,0,0,0]
["vinyl bromide","vinyl bromide","C003763",2,0,0,0,0]
["vinyl ether","vinyl ether","C100195",1,0,0,3,0]
["vinylidene chloride","vinylidene chloride","C029297",1,0,0,0,0]
["violaxanthin","violaxanthin","C005613",8,0,0,0,0]
["vipirinin","vipirinin","C558926",1,0,0,0,0]
["vipoxin","vipoxin","C033134",1,0,0,0,0]
["viral envelope lipids","viral envelope lipids","C050629",2,0,1,0,0]
["virginiamycin butanolide C","virginiamycin butanolide C","C052546",1,0,0,0,0]
["virodhamine","virodhamine","C456739",1,0,0,1,0]
["virstatin","virstatin","C505381",3,0,0,0,0]
["virulizin","virulizin","C087098",0,0,0,1,0]
["Vitamin K 2","Vitamin K 2","D024482",10,0,0,0,0]
["vitexin","vitexin","C032731",2,0,0,0,0]
["vitisin A","vitisin A","C412469",1,0,0,0,0]
["VLX1570","VLX1570","C000623193",1,0,0,0,0]
["VNI-41 compound","VNI-41 compound","C000604398",1,0,0,0,0]
["VNP 20009","VNP 20009","C465023",0,0,0,1,0]
["vofopitant","vofopitant","C103207",2,0,0,0,0]
["volinanserin","volinanserin","C079049",6,0,0,0,0]
["vorozole","vorozole","C060523",3,0,0,0,0]
["vortioxetine","vortioxetine","C557874",5,0,0,0,0]
["VP-4 vaccine","VP-4 vaccine","C088865",0,1,1,1,0]
["VRT 532","VRT 532","C535089",1,0,0,0,0]
["VT-1161","VT-1161","C000599187",1,0,0,0,0]
["VTX-2337","VTX-2337","C573973",0,0,3,0,0]
["VTX-294","VTX-294","C583177",0,0,1,0,0]
["VU 0155041","VU 0155041","C544970",1,0,0,0,0]
["VU0455691","VU0455691","C576464",1,0,0,0,0]
["VU0468809","VU0468809","C000599657",1,0,0,0,0]
["VU0486321","VU0486321","C000609686",1,0,0,0,0]
["VU6001192","VU6001192","C000605771",1,0,0,0,0]
["VUF5420","VUF5420","C515419",2,0,0,0,0]
["VUFB 12018","VUFB 12018","C018791",2,0,0,0,0]
["vulnibactin","vulnibactin","C086667",1,0,0,0,0]
["VX148","VX148","C465281",0,0,0,1,0]
["VX680","VX680","C484810",2,0,0,0,0]
["VX-745","VX-745","C464966",1,0,0,0,0]
["waglerin","waglerin","C077895",3,0,0,0,0]
["wALADin1 compound","wALADin1 compound","C583087",1,0,0,0,0]
["walrycin A","walrycin A","C574123",1,0,0,0,0]
["warfarin hexadecyl ether","warfarin hexadecyl ether","C094088",1,0,0,0,0]
["warifteine","warifteine","C003931",0,0,0,1,0]
["Wax D","Wax D","C009681",0,0,2,0,0]
["WAY 100135","WAY 100135","C081293",4,0,0,0,0]
["WAY 124466","WAY 124466","C081453",0,0,0,3,0]
["WAY 151693","WAY 151693","C414371",1,0,0,0,0]
["WC5 compound","WC5 compound","C586457",2,0,0,0,0]
["We 201","We 201","C006065",4,0,0,0,0]
["welwitindolinone C isothiocyanate","welwitindolinone C isothiocyanate","C092270",1,0,0,0,0]
["wentilactone B","wentilactone B","C454809",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C16004,B16004)","v":"Wf-516"},"Wf-516","C527744",2,0,0,0,0]
["WHI P154","WHI P154","C113888",0,0,3,3,0]
["WIKI4 compound","WIKI4 compound","C581555",1,0,0,0,0]
["wilsonol C","wilsonol C","C577256",1,0,0,0,0]
["WIN 17317-3","WIN 17317-3","C094805",0,0,0,3,0]
["Win 52084","Win 52084","C049869",0,0,1,0,0]
["WIN 53071","WIN 53071","C092959",0,0,0,1,0]
["Win 55212-2","Win 55212-2","C070417",8,0,0,12,0]
["WIN 61058","WIN 61058","C092960",0,0,0,1,0]
["WIN 61651","WIN 61651","C098117",0,0,0,3,0]
["withaferin A","withaferin A","C009684",20,3,0,6,0]
["withangulatin A","withangulatin A","C059043",0,0,0,3,0]
["wogonin","wogonin","C085514",8,3,6,7,0]
["wogonin-7-glucuronide","wogonin-7-glucuronide","C465289",0,0,1,0,0]
["wortmannin","wortmannin","C009687",6,0,7,21,0]
["WP 631","WP 631","C104426",1,0,0,3,0]
["WP1066","WP1066","C519885",0,0,0,3,0]
["WR 1065","WR 1065","C020174",4,0,0,10,0]
["WY-25105","WY-25105","C586188",1,0,0,0,0]
["X 910279","X 910279","C102911",0,0,0,12,0]
["Xamoterol","Xamoterol","D017307",1,0,0,0,0]
["xanomeline","xanomeline","C075257",3,0,0,0,0]
["xanthenone-4-acetic acid","xanthenone-4-acetic acid","C066138",2,0,0,0,0]
["xanthobilirubic acid","xanthobilirubic acid","C013337",1,0,0,0,0]
["xanthofulvin","xanthofulvin","C477901",1,0,0,0,0]
["xanthomegnin","xanthomegnin","C009688",2,0,0,0,0]
["xanthone","xanthone","C009689",5,0,0,3,0]
["Xanthopterin","Xanthopterin","D014976",3,0,0,0,0]
["xanthostigmine","xanthostigmine","C541438",1,0,0,0,0]
["xanthurenic acid","xanthurenic acid","C028330",8,0,0,0,0]
["XAX-162","XAX-162","C586762",1,0,0,0,0]
["XCT790","XCT790","C488234",1,0,0,0,0]
["xemilofiban","xemilofiban","C091295",1,0,0,0,0]
["xiaoyao","xiaoyao","C516449",0,3,0,0,0]
["XIB 4035","XIB 4035","C470912",2,0,0,0,0]
["xinfeng","xinfeng","C533622",0,0,0,4,0]
["XK 469","XK 469","C118180",2,0,0,0,0]
["XL765","XL765","C576808",0,0,0,1,0]
["XLR-11","XLR-11","C585106",2,0,0,0,0]
["XMD15-44","XMD15-44","C000605794",1,0,0,0,0]
["XR5944","XR5944","C434883",1,0,0,0,0]
["XR774","XR774","C429612",0,0,0,3,0]
["XU 063","XU 063","C107137",1,0,0,0,0]
["XUESETONG","XUESETONG","C509799",1,0,0,0,0]
["xylariphilone","xylariphilone","C000609425",0,0,3,0,0]
["xylenol orange","xylenol orange","C016833",1,0,0,0,0]
["xylobiose","xylobiose","C004173",3,0,0,0,0]
["xyloidone","xyloidone","C029244",0,3,0,0,0]
["xyloketal B","xyloketal B","C515343",2,0,0,0,0]
["xylopyranose","xylopyranose","C431715",1,0,0,0,0]
["xylose 1-phosphate","xylose 1-phosphate","C054739",0,0,1,1,0]
["Xylulose","Xylulose","D014996",1,0,0,0,0]
["xymedon","xymedon","C069705",0,0,0,18,0]
["Y 32885","Y 32885","C460080",1,0,0,0,0]
["Y 39041","Y 39041","C406663",2,0,0,3,0]
["Y-632 compound","Y-632 compound","C000613759",2,0,0,0,0]
["yakkasterone","yakkasterone","C082633",1,0,0,0,0]
["YCZ-18","YCZ-18","C000604930",1,0,0,0,0]
["yersiniabactin","yersiniabactin","C104398",1,0,0,0,0]
["yessotoxin","yessotoxin","C066632",5,0,0,6,0]
["YF 476","YF 476","C104428",1,0,0,0,0]
["YH 1885","YH 1885","C108798",1,0,0,0,0]
["YH 439","YH 439","C098009",2,0,0,0,0]
["yin-huang-qing-fei","yin-huang-qing-fei","C000622018",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C16068,B16068)","v":"yinqiaosan"},"yinqiaosan","C558279",1,0,0,0,0]
["yishen","yishen","C525740",0,0,0,3,0]
["YJC-10592","YJC-10592","C000613909",1,0,0,0,0]
["YKP 1358","YKP 1358","C518965",1,0,0,0,0]
["YM 155","YM 155","C523798",3,0,0,4,0]
["YM 26734","YM 26734","C084181",1,0,0,0,0]
["YM 511","YM 511","C096486",1,0,0,0,0]
["YM 529","YM 529","C087958",1,0,0,0,0]
["YNT-854","YNT-854","C000608969",1,0,0,0,0]
["YO-PRO 1","YO-PRO 1","C089813",0,0,0,1,0]
["you-gui-wan","you-gui-wan","C502768",0,0,3,6,0]
["younggaechulgam-tang","younggaechulgam-tang","C500217",0,0,0,3,0]
["YR301","YR301","C526404",1,0,0,0,0]
["ytterbium DTPA","ytterbium DTPA","C073846",1,0,0,0,0]
["yttrium ethylenediaminetetra(methylenephosphonic acid)","yttrium ethylenediaminetetra(methylenephosphonic acid)","C061699",1,0,0,0,0]
["yttrium(III)-1,4,7,10-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic acid","yttrium(III)-1,4,7,10-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic acid","C113625",1,0,0,0,0]
["yu ping feng san","yu ping feng san","C506362",1,0,0,7,0]
["YUA001","YUA001","C444199",0,0,0,1,0]
["yuanzhi-1","yuanzhi-1","C000604075",2,0,0,0,0]
["Z 338","Z 338","C410959",2,0,0,0,0]
["Z-10 nitro compound","Z-10 nitro compound","C000621791",1,0,0,0,0]
["zacopride","zacopride","C055971",1,0,0,0,0]
["zamifenacin","zamifenacin","C097932",1,0,0,0,0]
["zampanolide","zampanolide","C444900",2,0,0,0,0]
["zaprinast","zaprinast","C011145",1,0,0,0,0]
["zatosetron","zatosetron","C064877",1,0,0,0,0]
["ZCL278","ZCL278","C000610025",1,0,0,0,0]
["ZD4054","ZD4054","C511404",2,0,0,0,0]
["zearalenol","zearalenol","C029659",1,0,0,0,0]
["zearalenone-14-glucuronide","zearalenone-14-glucuronide","C000597750",1,0,0,0,0]
["Zeatin","Zeatin","D015026",4,1,0,0,0]
["ZEL-H16","ZEL-H16","C578331",2,0,0,0,0]
["zhankuic acid A","zhankuic acid A","C098367",1,0,0,3,0]
["ziconotide","ziconotide","C078452",6,0,0,0,0]
["Zimeldine","Zimeldine","D015031",1,0,0,1,0]
["zinc chelate-sepharose","zinc chelate-sepharose","C030523",1,0,0,0,0]
["zinc chlorin","zinc chlorin","C558702",1,0,0,0,0]
["zinc fluoride","zinc fluoride","C038904",1,0,0,0,0]
["zinc hematoporphyrin","zinc hematoporphyrin","C017802",1,0,0,0,0]
["zinc hydroxide","zinc hydroxide","C052745",1,0,0,0,0]
["zinc mesoporphyrin","zinc mesoporphyrin","C058069",1,0,0,0,0]
["zinc protoporphyrin","zinc protoporphyrin","C017803",5,0,1,0,0]
["zinc selenide","zinc selenide","C044696",2,0,0,0,0]
["ZINC12296427","ZINC12296427","C000612159",1,0,0,0,0]
["ZINC12389251","ZINC12389251","C000612160",1,0,0,0,0]
["ZINC13451138","ZINC13451138","C574249",1,0,0,0,0]
["zingerone","zingerone","C013738",0,3,0,0,0]
["zinpyr-1","zinpyr-1","C501987",0,0,0,2,0]
["zinquin","zinquin","C084731",1,0,0,0,0]
["zinterol","zinterol","C002904",1,0,0,0,0]
["ZK 118182","ZK 118182","C067426",1,0,0,0,0]
["ZK 156718","ZK 156718","C447607",1,0,0,0,0]
["ZK 200775","ZK 200775","C114423",0,0,0,1,0]
["ZK 93426","ZK 93426","C042568",1,0,0,0,0]
["ZK159222","ZK159222","C410228",1,0,0,0,0]
["ZM 241385","ZM 241385","C097270",7,0,0,0,0]
["ZM 253270","ZM 253270","C095798",1,0,0,0,0]
["ZnPc(COOH)16","ZnPc(COOH)16","C549929",1,0,0,0,0]
["zolpidem","zolpidem","C049109",11,0,0,0,0]
["zomepirac glucuronide","zomepirac glucuronide","C027368",3,0,0,0,0]
["zopiclone","zopiclone","C515050",2,0,0,0,0]
["zopolrestat","zopolrestat","C067172",3,0,0,0,0]
["zosteric acid","zosteric acid","C503399",1,0,0,0,0]
["zosterin","zosterin","C070927",0,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C16132,B16132)","v":"zosuquidar trihydrochloride"},"zosuquidar trihydrochloride","C095179",2,0,0,0,0]
["zoxamide","zoxamide","C451427",1,0,0,0,0]
["Zoxazolamine","Zoxazolamine","D015049",4,0,0,0,0]
["ZSTK474","ZSTK474","C510150",0,0,3,3,0]
["zuonin A","zuonin A","C579789",1,0,0,0,0]
["zwittergent 3-12","zwittergent 3-12","C034730",1,0,2,0,0]
["(4-chloro-2-((2-fluoro-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","(4-chloro-2-((2-fluoro-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","C568958",1,0,0,0,-1]
["(4-chloro-2-((2-methyl-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","(4-chloro-2-((2-methyl-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","C568957",1,0,0,0,-1]
["(5-(p-fluorophenyl)-2-ureido)thiophene-3-carboxamide","(5-(p-fluorophenyl)-2-ureido)thiophene-3-carboxamide","C586469",0,0,0,0,-1]
["1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one","1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one","C482649",0,0,0,0,-1]
["1,3-dicyclopentyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylic acid diethyl ester","1,3-dicyclopentyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylic acid diethyl ester","C587910",0,0,0,0,-1]
["1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate","1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate","C503118",0,0,0,0,-1]
["1,4-diphenyl-2-mercaptoimidazole","1,4-diphenyl-2-mercaptoimidazole","C545737",0,0,0,3,-1]
["12-acetoxyhawtriwaic acid lactone","12-acetoxyhawtriwaic acid lactone","C513234",0,0,0,0,-1]
["18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate","18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate","C521270",0,0,0,1,-1]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129",3,6,7,14,-1]
["1-triacontanol","1-triacontanol","C047578",0,0,0,0,-1]
["2-((4-methylthiopyridin-2-yl)methylsulfinyl)benzimidazole","2-((4-methylthiopyridin-2-yl)methylsulfinyl)benzimidazole","C419888",0,0,0,0,-1]
["2-(3-pyridylmethyl)indazolinone","2-(3-pyridylmethyl)indazolinone","C063962",0,0,0,0,-1]
["2-(6-((3-(4-(diphenylmethoxy)piperidino)propyl)amino)imidazo(1,2-b)pyridazin-2-yl)-2-methylpropionic acid","2-(6-((3-(4-(diphenylmethoxy)piperidino)propyl)amino)imidazo(1,2-b)pyridazin-2-yl)-2-methylpropionic acid","C469683",0,0,0,0,-1]
["2,3-dichloro-1-propanol","2,3-dichloro-1-propanol","C076159",0,0,0,3,-1]
["21-deacetyldeflazacort","21-deacetyldeflazacort","C048465",0,0,0,3,-1]
["2-aminobenzimidazole","2-aminobenzimidazole","C027391",0,0,3,0,-1]
["2-aminophenol","2-aminophenol","C027667",0,0,0,0,-1]
["2-cyclohexylimino-6-methyl-6,7-dihydro-5H-benzo(1,3)oxathiol-4-one","2-cyclohexylimino-6-methyl-6,7-dihydro-5H-benzo(1,3)oxathiol-4-one","C561472",0,0,0,0,-1]
["2-hydroxy-N,N-dimethyl-3-(2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-enylamino)benzamide","2-hydroxy-N,N-dimethyl-3-(2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-enylamino)benzamide","C516686",2,0,0,0,-1]
["3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole","3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole","C030266",1,0,0,9,-1]
["3beta,6beta-dihydroxyolean-12-en-27-oic acid","3beta,6beta-dihydroxyolean-12-en-27-oic acid","C494851",0,0,0,0,-1]
["3-isobutanoyl-1-(2-oxo-3-(4-phenoxyphenoxy)propyl)indole-5-carboxylic acid","3-isobutanoyl-1-(2-oxo-3-(4-phenoxyphenoxy)propyl)indole-5-carboxylic acid","C551617",0,0,0,0,-1]
["3'-O-methylastilbin","3'-O-methylastilbin","C518533",0,0,0,0,-1]
["4-(((2-aminophenyl)amino)-2-chlorophenyl)(2-methylphenyl)methanone","4-(((2-aminophenyl)amino)-2-chlorophenyl)(2-methylphenyl)methanone","C480609",0,0,0,0,-1]
["4-(2',4'-difluorobiphenyl-4-yl)-2-methylbutyric acid","4-(2',4'-difluorobiphenyl-4-yl)-2-methylbutyric acid","C504193",0,0,0,0,-1]
["4-(4-(aminomethyl)-7a-methyl-1-methylideneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexan-1-ol","4-(4-(aminomethyl)-7a-methyl-1-methylideneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexan-1-ol","C582990",0,0,0,0,-1]
["4-benzyloxy-5-((5-undecyl-2H-pyrrol-2-ylidene)methyl)-2,2'-bi-1H-pyrrole","4-benzyloxy-5-((5-undecyl-2H-pyrrol-2-ylidene)methyl)-2,2'-bi-1H-pyrrole","C119625",0,0,0,6,-1]
["4-cyano-4-(2,3-dihydro-8-methoxy-1,4-benzodioxin-5-yl)cyclohexanecarboxylic acid","4-cyano-4-(2,3-dihydro-8-methoxy-1,4-benzodioxin-5-yl)cyclohexanecarboxylic acid","C539236",0,0,0,0,-1]
["4-estren-3,17-diol","4-estren-3,17-diol","C468666",0,0,0,3,-1]
["5-(4-phenylbutoxy)psoralen","5-(4-phenylbutoxy)psoralen","C499898",0,0,0,10,-1]
["5-fluoro-2-(2-(1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta(f)indazol-5-yl)ethyl)benzamide","5-fluoro-2-(2-(1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta(f)indazol-5-yl)ethyl)benzamide","C000592348",0,0,0,0,-1]
["5-O-demethylnobiletin","5-O-demethylnobiletin","C509545",0,0,0,3,-1]
["6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole","6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole","C052026",2,0,0,0,-1]
["6(A)-O-(2-(3-benzoylphenyl)propionyl)-alpha-cyclodextrin","6(A)-O-(2-(3-benzoylphenyl)propionyl)-alpha-cyclodextrin","C467719",0,0,0,0,-1]
["6H,6-(2-(dimethylamino)ethoxycarbonyl)dibenzo(b,d)pyran","6H,6-(2-(dimethylamino)ethoxycarbonyl)dibenzo(b,d)pyran","C051455",0,0,0,0,-1]
["7'-(3',4'-dihydroxyphenyl)-N-((4-methoxyphenyl)ethyl)propenamide","7'-(3',4'-dihydroxyphenyl)-N-((4-methoxyphenyl)ethyl)propenamide","C460621",0,0,0,1,-1]
["A1443 compound","A1443 compound","C000591860",0,0,0,0,-1]
["ABT 281","ABT 281","C119392",0,0,0,0,-1]
["alpinetin","alpinetin","C436748",2,0,0,3,-1]
["AnCoA4 compound","AnCoA4 compound","C000599361",1,0,0,3,-1]
["apigetrin","apigetrin","C057792",0,0,0,0,-1]
["Ashwagandha","Ashwagandha","C030693",0,0,0,0,-1]
["bamipine","bamipine","C020867",0,0,0,0,-1]
["batridene","batridene","C016259",0,0,0,4,-1]
["bermoprofen","bermoprofen","C040006",0,0,0,1,-1]
["beta-Oxa 21-3n-3 fatty acid","beta-Oxa 21-3n-3 fatty acid","C439390",0,0,0,3,-1]
["bicarphene","bicarphene","C018139",0,0,0,0,-1]
["BIRT 377","BIRT 377","C400461",4,0,0,0,-1]
["bisindolylmaleimide I","bisindolylmaleimide I","C070515",2,6,0,1,-1]
["bryonolic acid","bryonolic acid","C074984",0,0,0,0,-1]
["bu-zhong-yi-qi-tang","bu-zhong-yi-qi-tang","C402943",0,1,5,4,-1]
["byakkokakeishito","byakkokakeishito","C000590803",0,0,0,0,-1]
["centipedic acid","centipedic acid","C531023",0,0,0,0,-1]
["Chunghyuldan","Chunghyuldan","C499382",0,0,0,0,-1]
["cistoran","cistoran","C060810",0,0,0,0,-1]
["dammarane","dammarane","C102963",1,0,0,3,-1]
["denotivir","denotivir","C109918",0,0,0,0,-1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C16196,B16196)","v":"dexamethasone acetate"},"dexamethasone acetate","C018038",0,0,0,1,-1]
["Dichloroacetic Acid","Dichloroacetic Acid","D003999",8,0,0,4,-1]
["dihydrocucurbitacin B","dihydrocucurbitacin B","C523469",0,0,0,0,-1]
["dihydrolipoic acid","dihydrolipoic acid","C015144",10,3,0,7,-1]
["Doxazosin","Doxazosin","D017292",7,0,0,0,-1]
["DSKB-2 compound","DSKB-2 compound","C496224",0,0,1,0,-1]
["DW-116","DW-116","C097673",0,0,0,0,-1]
["ER 38925","ER 38925","C406083",0,0,0,0,-1]
["flumizole","flumizole","C011252",0,0,0,0,-1]
["Fujibitol","Fujibitol","C121689",0,0,0,0,-1]
["glycyrol","glycyrol","C531349",0,0,0,3,-1]
["glyteen","glyteen","C007876",0,1,0,0,-1]
["GW9508","GW9508","C515630",1,3,0,0,-1]
["hemodes","hemodes","C007918",0,0,0,2,-1]
["herpetol","herpetol","C000617972",0,0,0,3,-1]
["histapyrrodine","histapyrrodine","C049920",0,0,0,0,-1]
["IM 133","IM 133","C121167",0,0,0,0,-1]
["IMMLG5521","IMMLG5521","C561127",0,0,0,0,-1]
["immunomycin","immunomycin","C058028",7,3,0,23,-1]
["indan","indan","C093582",1,0,1,0,-1]
["indoxacarb","indoxacarb","C401104",0,0,0,0,-1]
["irisflorentin","irisflorentin","C570745",0,0,3,0,-1]
["isogarcinol","isogarcinol","C000617954",0,0,0,3,-1]
["jaceosidin","jaceosidin","C477508",0,0,0,3,-1]
["JM 34","JM 34","C096171",0,0,3,6,-1]
["JTE-052","JTE-052","C000621572",0,0,1,1,-1]
["L 651896","L 651896","C053727",0,0,0,0,-1]
["levocabastine","levocabastine","C047340",3,0,1,0,-1]
["licofelone","licofelone","C088092",0,0,0,0,-1]
["limonin","limonin","C001546",0,0,1,4,-1]
["linoleoyl ethanolamide","linoleoyl ethanolamide","C109347",0,0,0,0,-1]
["lipopolysaccharide IP-PA1, Pantoea agglomerans","lipopolysaccharide IP-PA1, Pantoea agglomerans","C524847",0,0,0,0,-1]
["Lymecycline","Lymecycline","D008194",0,0,0,0,-1]
["MAS063DP","MAS063DP","C530270",0,0,0,0,-1]
["MDL 29311","MDL 29311","C071022",0,0,0,0,-1]
["methyl 3-octanoyloxyiminoolean-12-en-28-oate","methyl 3-octanoyloxyiminoolean-12-en-28-oate","C578345",0,0,0,0,-1]
["moku-boi-to","moku-boi-to","C099755",0,0,0,0,-1]
["monocyte-macrophage differentiation antigen","monocyte-macrophage differentiation antigen","C036763",1,0,11,9,-1]
["N-(2-adamantyl)hexamethylenimine","N-(2-adamantyl)hexamethylenimine","C122112",0,0,0,0,-1]
["N-Acetylneuraminic Acid","N-Acetylneuraminic Acid","D019158",169,4,31,41,-1]
["n-hexane","n-hexane","C026385",0,0,0,3,-1]
["NVP-QAV680","NVP-QAV680","C588117",1,0,0,0,-1]
["olvanil","olvanil","C054256",0,0,0,0,-1]
["periplocoside E","periplocoside E","C509135",0,0,3,6,-1]
["phellodendrine","phellodendrine","C079418",0,0,0,0,-1]
["Phenformin","Phenformin","D010629",3,0,0,0,-1]
["physalin E","physalin E","C553897",0,0,0,0,-1]
["piclamilast","piclamilast","C087566",1,0,0,3,-1]
["pinocembrin","pinocembrin","C016063",0,0,0,0,-1]
["polymethacrylic acid","polymethacrylic acid","C030613",4,0,5,0,-1]
["porphyran","porphyran","C038549",0,0,0,0,-1]
["prifelone","prifelone","C037195",0,0,0,0,-1]
["prinomide","prinomide","C052921",2,0,0,1,-1]
["Prodigiosin","Prodigiosin","D011353",8,0,11,29,-1]
["Pro-Q aerosol foam","Pro-Q aerosol foam","C118954",0,0,0,0,-1]
["PS3 glucan","PS3 glucan","C532541",0,0,0,0,-1]
["pseudolaric acid B","pseudolaric acid B","C058391",3,0,0,12,-1]
["pyrazolo(3,4-d)pyrimidine","pyrazolo(3,4-d)pyrimidine","C014175",3,0,0,3,-1]
["repirinast","repirinast","C048522",0,0,0,0,-1]
["risarestat","risarestat","C051003",0,0,0,0,-1]
["saikosaponin","saikosaponin","C025759",2,0,0,17,-1]
["Salvia extract","Salvia extract","C528662",0,1,0,3,-1]
["Sch 036","Sch 036","C526688",0,0,0,0,-1]
["SDK 47","SDK 47","C038338",0,0,0,0,-1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C16260,B16260)","v":"SDK 50"},"SDK 50","C038339",0,0,0,0,-1]
["shark cartilage extract","shark cartilage extract","C111481",2,0,0,0,-1]
["ShK neurotoxin","ShK neurotoxin","C095391",4,0,0,21,-1]
["SK&F 105809","SK&F 105809","C067914",0,0,0,3,-1]
["Solifenacin Succinate","Solifenacin Succinate","D000069464",5,0,0,0,-1]
["SR 144528","SR 144528","C110630",2,0,0,0,-1]
["stephanthraniline A","stephanthraniline A","C555640",0,0,0,9,-1]
["Thomsen-Friedenreich antigen","Thomsen-Friedenreich antigen","C016467",21,0,9,8,-1]
["thunberginol A","thunberginol A","C079055",0,0,1,3,-1]
["tiacrilast","tiacrilast","C040252",0,0,0,0,-1]
["tiliroside","tiliroside","C052083",1,0,0,0,-1]
["tipredane","tipredane","C051756",0,0,0,3,-1]
["traxanox","traxanox","C020178",0,0,0,6,-1]
["trikatu","trikatu","C540456",0,0,0,0,-1]
["tylophorine","tylophorine","C004218",2,0,1,0,-1]
["Vardenafil Dihydrochloride","Vardenafil Dihydrochloride","D000069058",4,0,0,0,-1]
["vaticaffinol","vaticaffinol","C579359",0,0,0,3,-1]
["verbascosaponin","verbascosaponin","C406482",0,0,0,0,-1]
["verbascose","verbascose","C570815",0,0,0,0,-1]
["VUF-K 8788","VUF-K 8788","C121690",0,0,0,0,-1]
["wuhua","wuhua","C550103",0,0,0,0,-1]
["Xuebijing","Xuebijing","C549376",1,0,3,4,-1]
["YM 13650","YM 13650","C069510",0,0,0,0,-1]
["yupingfeng","yupingfeng","C532967",0,0,0,0,-1]
["zanhasaponin A","zanhasaponin A","C109949",0,0,0,0,-1]
["zanhasaponin B","zanhasaponin B","C109950",0,0,0,0,-1]
["ZCR 2060","ZCR 2060","C091433",0,0,0,0,-1]
["zhankuic acid C","zhankuic acid C","C098428",0,0,3,0,-1]
["ZK 191784","ZK 191784","C470666",0,0,3,1,-1]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949",8,12,17,12,-2]
["5-(benzoylamino)-N-(4-chlorophenyl)-3-methyl-4-isothiazolecarboxamide","5-(benzoylamino)-N-(4-chlorophenyl)-3-methyl-4-isothiazolecarboxamide","C027999",1,0,0,0,-2]
["6-ethyl-3-(1H-tetrazol-5-yl)chromone","6-ethyl-3-(1H-tetrazol-5-yl)chromone","C018537",0,0,0,0,-2]
["ablukast","ablukast","C053877",0,0,0,0,-2]
["adelmidrol","adelmidrol","C552602",0,3,0,0,-2]
["aprepitant","aprepitant","C114556",5,0,0,0,-2]
["clocortolone pivalate","clocortolone pivalate","C007088",0,0,0,0,-2]
["fipronil","fipronil","C082360",3,0,0,0,-2]
["lotifazole","lotifazole","C040605",0,0,0,0,-2]
["N-(4,6-dimethylpyrimidin-2-yl)-4-(2-(4-methoxy-3-methylphenyl)-5-(4-methylpiperazin-1-yl)-4,5,6,7-tetrahydro-1H-indol-1-yl)benzenesulfonamide difumarate","N-(4,6-dimethylpyrimidin-2-yl)-4-(2-(4-methoxy-3-methylphenyl)-5-(4-methylpiperazin-1-yl)-4,5,6,7-tetrahydro-1H-indol-1-yl)benzenesulfonamide difumarate","C514969",0,0,0,3,-2]
["quinoxaline-2-carboxylic acid (4-carbamoyl-1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyloctyl)amide","quinoxaline-2-carboxylic acid (4-carbamoyl-1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyloctyl)amide","C479133",2,0,0,0,-2]
["telcagepant","telcagepant","C525458",5,0,0,0,-2]
["tripterine","tripterine","C050414",15,6,3,1,-2]

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["Detail - AOP "]
["Chemical MeSH Name (hyperlinked)","ChemName","chemuid","catord","event_id","event_order","Event Process","Event Action","MeSH term (hyperlinked)","uid","MeSHterm","basescore","Score","Pub Yr","pmid","Title","LinkPMID","aop_id"]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3,B3)","v":"(((((4-hydroxy-4,4-diphosphonobutyl)carbamoylmethyl)carbamoylmethyl)carbamoylmethyl)carbamoylmethanethiolate)oxorhenium(V)"},"(((((4-hydroxy-4,4-diphosphonobutyl)carbamoylmethyl)carbamoylmethyl)carbamoylmethyl)carbamoylmethanethiolate)oxorhenium(V)","C517422","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J3,K3)","v":"Protein Binding"},"D011485","Protein Binding",1,2,2009,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q3,Q3)","v":"18709369"},"Usefulness of competitive inhibitors of protein binding for improving the pharmacokinetics of 186Re-MAG3-conjugated bisphosphonate (186Re-MAG3-HBP), an agent for treatment of painful bone metastases.","18709369",40]
["(((4-chloromethyl)benzoyl)amino)-tetramethylrhodamine","(((4-chloromethyl)benzoyl)amino)-tetramethylrhodamine","C116572","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,2002,"11911670","Use of CMFDA and CMTMR fluorescent dyes in FACS-based antibody screening.","11911670",40]
["((17-N-cyclobutylmethyl)morphinan-3-yl-(-14-hydroxyl-17-N-cyclobutylmethyl) morphinan-3-yl) decanedioate","((17-N-cyclobutylmethyl)morphinan-3-yl-(-14-hydroxyl-17-N-cyclobutylmethyl) morphinan-3-yl) decanedioate","C560330","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21482470","Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors.","21482470",40]
["((18)F)2-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione","((18)F)2-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione","C586766","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23816046","Synthesis and in vivo evaluation of [(18)F]2-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione ([(18)F]FECUMI-101) as an imaging probe for 5-HT1A receptor agonist in nonhuman primates.","23816046",40]
["((1-isopropyl-3-(3-methoxy-tetrahydro-2H-pyran-4-ylamino)cyclopentyl)(4-(5-(trifluoromethyl)pyridazin-3-yl)piperazin-1-yl)methanone)","((1-isopropyl-3-(3-methoxy-tetrahydro-2H-pyran-4-ylamino)cyclopentyl)(4-(5-(trifluoromethyl)pyridazin-3-yl)piperazin-1-yl)methanone)","C560206","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21315584","Discovery of ((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-4-ylamino)cyclopentyl)(4-(5-(trifluoromethyl)pyridazin-3-yl)piperazin-1-yl)methanone, PF-4254196, a CCR2 antagonist with an improved cardiovascular profile.","21315584",40]
["((2,3-difluorobenzyl) 5-fluoroacetamido-9-(4-chlorobenzamido)-3,5,9-trideoxy-d-glycerogalacto-2-nonulopyranosid)onic acid","((2,3-difluorobenzyl) 5-fluoroacetamido-9-(4-chlorobenzamido)-3,5,9-trideoxy-d-glycerogalacto-2-nonulopyranosid)onic acid","C547949","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20095613","Low molecular weight antagonists of the myelin-associated glycoprotein: synthesis, docking, and biological evaluation.","20095613",40]
["((4-methyl(1,2,4)triazolo(4,3-a)quinolin-1-yl)sulfanyl)acetic acid","((4-methyl(1,2,4)triazolo(4,3-a)quinolin-1-yl)sulfanyl)acetic acid","C000606089","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26078037","Structure-based design of diverse inhibitors of Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase: combined molecular docking, dynamic simulation, and biological activity.","26078037",40]
["((5Z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4-one)","((5Z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4-one)","C578491","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22998443","Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.","22998443",40]
["((7R)-7-(((4-fluorophenyl)sulfonyl)(methyl)amino)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)acetic acid","((7R)-7-(((4-fluorophenyl)sulfonyl)(methyl)amino)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)acetic acid","C554899","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"20943773","Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist.","20943773",40]
["(+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid","(+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid","C095804","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7562513","The pharmacology of SCH 50911: a novel, orally-active GABA-beta receptor antagonist.","7562513",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2012,"22802445","BET bromodomain inhibition as a novel strategy for reactivation of HIV-1.","22802445",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2015,"25822022","Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations.","25822022",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2015,"25725100","Inhibiting STAT5 by the BET bromodomain inhibitor JQ1 disrupts human dendritic cell maturation.","25725100",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24497639","Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.","24497639",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26253517","Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression.","26253517",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"26573731","JQ1, an inhibitor of the epigenetic reader BRD4, suppresses the bidirectional MYC-AP4 axis via multiple mechanisms.","26573731",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"26735014","Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.","26735014",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27167393","Chemical probes: A shared toolbox.","27167393",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27292261","The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer.","27292261",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27443262","Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors.","27443262",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2017,"28107481","BET-Inhibitors Disrupt Rad21-Dependent Conformational Control of KSHV Latency.","28107481",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"25725100","Inhibiting STAT5 by the BET bromodomain inhibitor JQ1 disrupts human dendritic cell maturation.","25725100",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"26225771","Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation.","26225771",40]
["(+)-JQ1 compound","(+)-JQ1 compound","C561695","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"26387944","Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression.","26387944",40]
["(+)-methyl 2-((4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)methyl)-1-phenylcyclopropanecarboxylate","(+)-methyl 2-((4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)methyl)-1-phenylcyclopropanecarboxylate","C479880","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21476493","Novel potent and selective σ ligands: evaluation of their agonist and antagonist properties.","21476493",40]
["(+,-)-1-cyclohexyl-4-(1,2-diphenylethyl)piperazine","(+,-)-1-cyclohexyl-4-(1,2-diphenylethyl)piperazine","C012631","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2016,"26835687","[Acute cutaneous symptom complex with subsequent cataract. The internet drug MT-45 may be the cause].","26835687",40]
["(+,-)-1-cyclohexyl-4-(1,2-diphenylethyl)piperazine","(+,-)-1-cyclohexyl-4-(1,2-diphenylethyl)piperazine","C012631","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2017,"27976363","Acute skin and hair symptoms followed by severe, delayed eye complications in subjects using the synthetic opioid MT-45.","27976363",40]
["(1-((5-methyl-3-(2-methylsulfonylphenylsulfonyloxy)phenoxyl)methyl) cyclopropylmethoxy)guanidine hydrochloride","(1-((5-methyl-3-(2-methylsulfonylphenylsulfonyloxy)phenoxyl)methyl) cyclopropylmethoxy)guanidine hydrochloride","C530122","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18186144","Pharmacokinetic properties of TDP4815 after single intravenous and oral administrations to rat, rabbit, monkey, dog and in vitro drug metabolism.","18186144",40]
["(1-(2,2-diphenyl-(1,3)dioxolan-4-yl)-ethyl)-dimethyl-amine","(1-(2,2-diphenyl-(1,3)dioxolan-4-yl)-ethyl)-dimethyl-amine","C425227","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2001,"11206470","Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]-dimethyl-amine.","11206470",40]
["(1-(2-methoxy-phenyl)-3-naphthalen-2-yl-urea)","(1-(2-methoxy-phenyl)-3-naphthalen-2-yl-urea)","C496792","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2004,"15102890","Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide.","15102890",40]
["(1-(3-aminophenyl)-1H-pyrrol-3-yl)(3,4,5-trimethoxyphenyl)methanone","(1-(3-aminophenyl)-1H-pyrrol-3-yl)(3,4,5-trimethoxyphenyl)methanone","C000594994","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25025991","New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.","25025991",40]
["(1-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yl)methyl methanesulfonate","(1-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yl)methyl methanesulfonate","C587902","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27779815","Synthesis and biological evaluation of 1, 2, 4-oxadiazole derivatives as novel GPR119 agonists.","27779815",40]
["(1'-(4-fluorophenyl)(ethylenedioxy))pregn-4-ene-3,20-dione","(1'-(4-fluorophenyl)(ethylenedioxy))pregn-4-ene-3,20-dione","C081099","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8387596","Progestin 16 alpha, 17 alpha-dioxolane ketals as molecular probes for the progesterone receptor: synthesis, binding affinity, and photochemical evaluation.","8387596",40]
["(1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo(f)indazol-5-yl)-(4-(trifluoromethyl)phenyl)methanol","(1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo(f)indazol-5-yl)-(4-(trifluoromethyl)phenyl)methanol","C548783","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20065017","Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone.","20065017",40]
["(1-(4'-methoxybiphenyl-4-sulfonylamino)-2-methylpropyl) phosphonate","(1-(4'-methoxybiphenyl-4-sulfonylamino)-2-methylpropyl) phosphonate","C517802","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17228863","Stereoselectivity by enantiomeric inhibitors of matrix metalloproteinase-8: new insights from molecular dynamics simulations.","17228863",40]
["(1,2,3,9-tetrahydro-3-((5-methyl-1H-imidazol-4-yl)methyl)-9-(3-amino-(N-fluorescien-thiocarbamoyl)-propyl)-4H-carbazol-4-one)","(1,2,3,9-tetrahydro-3-((5-methyl-1H-imidazol-4-yl)methyl)-9-(3-amino-(N-fluorescien-thiocarbamoyl)-propyl)-4H-carbazol-4-one)","C115991","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23494379","Characterization and validation of fluorescent receptor ligands: a case study of the ionotropic serotonin receptor.","23494379",40]
["(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane","(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane","C478160","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22210352","Ethaselen: a potent mammalian thioredoxin reductase 1 inhibitor and novel organoselenium anticancer agent.","22210352",40]
["(1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine)dichloroplatinum (II)","(1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine)dichloroplatinum (II)","C078283","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7520852","Reversible and irreversible interactions of a cisplatin analog bearing a 1,2-diphenylethylenediamine ligand with plasma and plasma proteins in vitro.","7520852",40]
["(1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine)dichloroplatinum (II)","(1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine)dichloroplatinum (II)","C078283","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"11199469","Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part II. Studies on the influence of [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine] dichloroplatinum(II) on the specific immune defense in MXT-M-3,2 breast cancer bearing mice.","11199469",40]
["(1,2-bis(6-methoxy-2H-chromen-3-yl)methylene)hydrazine","(1,2-bis(6-methoxy-2H-chromen-3-yl)methylene)hydrazine","C000596021","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2014,"25056546","Effects of the novel compound DK223 ([1E,2E-1,2-Bis(6-methoxy-2H-chromen-3-yl)methylene]hydrazine) on migration and proliferation of human keratinocytes and primary dermal fibroblasts.","25056546",40]
["(1,4,7-trimethyl-1,4,7-triazacyclononane)iron(III)","(1,4,7-trimethyl-1,4,7-triazacyclononane)iron(III)","C112451","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9547264","(1,4,7-trimethyl-1,4,7-triazacyclononane)iron (III)-mediated cleavage of DNA: detection of selected protein-DNA interactions.","9547264",40]
["(10)-shogaol","(10)-shogaol","C585130","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2012,"22408422","10-Shogaol, an antioxidant from Zingiber officinale for skin cell proliferation and migration enhancer.","22408422",40]
["(10)-shogaol","(10)-shogaol","C585130","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22408422","10-Shogaol, an antioxidant from Zingiber officinale for skin cell proliferation and migration enhancer.","22408422",40]
["(10-benzyl-(1,2,4)triazino(4,3-a)benzimidazol-3,4(10H)-dion-2-yl)acetic acid","(10-benzyl-(1,2,4)triazino(4,3-a)benzimidazol-3,4(10H)-dion-2-yl)acetic acid","C442801","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11728182","[1,2,4]Triazino[4,3-a]benzimidazole acetic acid derivatives: a new class of selective aldose reductase inhibitors.","11728182",40]
["(11C)-(+)-alpha-dihydrotetrabenazine","(11C)-(+)-alpha-dihydrotetrabenazine","C575320","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26749375","Interpreting DTBZ binding data in rodent: Inherent variability and compensation.","26749375",40]
["(11C)-(+)-alpha-dihydrotetrabenazine","(11C)-(+)-alpha-dihydrotetrabenazine","C575320","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"29031997","A six-year longitudinal PET study of (+)-[11C]DTBZ binding to the VMAT2 in monkey brain.","29031997",40]
["(11-trichlorosilylundecanyl)-benzenethiosulfonate","(11-trichlorosilylundecanyl)-benzenethiosulfonate","C000604615","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,2015,"25955536","Adlayer-mediated antibody immobilization to stainless steel for potential application to endothelial progenitor cell capture.","25955536",40]
["(1-3)-(1-4)-glucan","(1-3)-(1-4)-glucan","C119131","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23229556","Understanding how noncatalytic carbohydrate binding modules can display specificity for xyloglucan.","23229556",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2014,"24200858","The effects of feed-borne Fusarium mycotoxins and glucomannan in turkey poults based on specific and non-specific parameters.","24200858",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2004,"15630191","The ability of konjac-glucomannan to suppress spontaneously occurring dermatitis in NC/Nga mice depends upon the particle size.","15630191",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2008,"17938942","Development of autoantibody responses in NC/Nga mice: its prevention by pulverized konjac glucomannan feeding.","17938942",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2004,"22454998","[Studies on the antidiabetic effect of konjac glucomannan with different molecular chains on experimental diabetes mice].","22454998",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,2006,"16393272","Oral administration of pulverized Konjac glucomannan prevents the increase of plasma immunoglobulin E and immunoglobulin G levels induced by the injection of syngeneic keratinocyte extracts in BALB/c mice.","16393272",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2006,"16393272","Oral administration of pulverized Konjac glucomannan prevents the increase of plasma immunoglobulin E and immunoglobulin G levels induced by the injection of syngeneic keratinocyte extracts in BALB/c mice.","16393272",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2008,"18067882","Photoprotective effects of glucomannan isolated from Candida utilis.","18067882",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24324599","Deciphering ligand specificity of a Clostridium thermocellum family 35 carbohydrate binding module (CtCBM35) for gluco- and galacto- substituted mannans and its calcium induced stability.","24324599",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2004,"15630191","The ability of konjac-glucomannan to suppress spontaneously occurring dermatitis in NC/Nga mice depends upon the particle size.","15630191",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"26676961","Beneficial health characteristics of native and hydrolysed konjac (Amorphophallus konjac) glucomannan.","26676961",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2005,"15722635","A new immunomodulatory function of low-viscous konjac glucomannan with a small particle size: its oral intake suppresses spontaneously occurring dermatitis in NC/Nga mice.","15722635",40]
["(1-6)-alpha-glucomannan","(1-6)-alpha-glucomannan","C022901","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2010,"20016194","Hydrolyzed Konjac glucomannan suppresses IgE production in mice B cells.","20016194",40]
["(18F)FEMPA","(18F)FEMPA","C000602344","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25412766","Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer's disease patients and control subjects.","25412766",40]
["(18F)fluoro-deoxy-glucose folate","(18F)fluoro-deoxy-glucose folate","C574334","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22372827","[18F]fluoro-deoxy-glucose folate: a novel PET radiotracer with improved in vivo properties for folate receptor targeting.","22372827",40]
["(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone","(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone","C586710","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23916483","Cannabinoids in disguise: Δ9-tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles.","23916483",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10037481","Modeling of the interaction of Na+ and K+ with the binding of dopamine and [3H]WIN 35,428 to the human dopamine transporter.","10037481",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C67,B67)","v":"(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester"},"(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J67,K67)","v":"Protein Binding"},"D011485","Protein Binding",1,2,2001,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q67,Q67)","v":"11181843"},"Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter.","11181843",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11989984","The functional domains of dopamine transporter for cocaine analog, CFT binding.","11989984",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12846549","Age-related changes of the [11C]CFT binding to the striatal dopamine transporters in the Fischer 344 rats: a PET study.","12846549",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14635728","Molecular model of the neural dopamine transporter.","14635728",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2004,"15140185","Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.","15140185",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2004,"15588620","Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter.","15588620",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15714477","Enhanced binding of dopamine D1 receptors in caudate-putamen subregions in High-Yawning Sprague-Dawley rats.","15714477",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16733812","Binding of 3H-WIN-35,428 and 125I-RTI-121 to human platelet membranes.","16733812",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1795555","A rapid binding assay for solubilized dopamine transporters using [3H]WIN 35,428.","1795555",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"17978168","Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.","17978168",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2008,"18606182","Different effects of selective dopamine uptake inhibitors, GBR 12909 and WIN 35428, on HIV-1 Tat toxicity in rat fetal midbrain neurons.","18606182",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2008,"18634806","Differential cocaine-induced modulation of glutamate and dopamine transporters after contingent and non-contingent administration.","18634806",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19138725","In vitro binding assays using (3)H nisoxetine and (3)H WIN 35,428 reveal selective effects of gonadectomy and hormone replacement in adult male rats on norepinephrine but not dopamine transporter sites in the cerebral cortex.","19138725",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19181264","Dopamine transporter binding in rat striatum: a comparison of [O-methyl-11C]beta-CFT and [N-methyl-11C]beta-CFT.","19181264",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19233481","Decreased brain dopamine cell numbers in human cocaine users.","19233481",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19325033","HIV-1 Tat protein-induced rapid and reversible decrease in [3H]dopamine uptake: dissociation of [3H]dopamine uptake and [3H]2beta-carbomethoxy-3-beta-(4-fluorophenyl)tropane (WIN 35,428) binding in rat striatal synaptosomes.","19325033",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"20855444","Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability.","20855444",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23564231","Mice expressing markedly reduced striatal dopamine transporters exhibit increased locomotor activity, dopamine uptake turnover rate, and cocaine responsiveness.","23564231",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23933243","Non-dioxin-like PCBs inhibit [(3)H]WIN-35,428 binding to the dopamine transporter: a structure-activity relationship study.","23933243",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2015,"25580950","Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities.","25580950",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1993,"8111003","Characterization of [125I]RTI-55 binding to dog caudate dopamine transporter.","8111003",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9083473","3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.","9083473",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9282933","Cations affect [3H]mazindol and [3H]WIN 35,428 binding to the human dopamine transporter in a similar fashion.","9282933",40]
["(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester","C021279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9593100","Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain.","9593100",40]
["(1R,4S,6R)-N-((1R)-2-(4-cyclohexyl-4-(((1,1-dimethylethyl)amino)carbonyl)-1-piperidinyl-1-((4-fluorophenyl)methyl)-2-oxoethyl)-2-methyl-2-azabicyclo(2.2.2)octane-6-carboxamide)","(1R,4S,6R)-N-((1R)-2-(4-cyclohexyl-4-(((1,1-dimethylethyl)amino)carbonyl)-1-piperidinyl-1-((4-fluorophenyl)methyl)-2-oxoethyl)-2-methyl-2-azabicyclo(2.2.2)octane-6-carboxamide)","C504378","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15982875","Discovery and activity of (1R,4S,6R)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-2-methyl-2-azabicyclo[2.2.2]octane-6-carboxamide (3, RY764), a potent and selective melanocortin subtype-4 receptor agonist.","15982875",40]
["(2-((2-((dimethylamino)methyl)-4-iodophenyl)thio)phenyl)methanol","(2-((2-((dimethylamino)methyl)-4-iodophenyl)thio)phenyl)methanol","C581853","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23265880","A new single-photon emission computed tomography (SPECT) imaging agent for serotonin transporters: [(125)I]Flip-IDAM, (2-((2-((dimethylamino)methyl)-4-iodophenyl)thio)phenyl)methanol.","23265880",40]
["(2-((3,5-di-t-butyl-4-hydroxyphenyl)thio)-1-methylpropoxy)acetic acid","(2-((3,5-di-t-butyl-4-hydroxyphenyl)thio)-1-methylpropoxy)acetic acid","C066992","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1991,"1989152","Immunosuppressive properties of enisoprost and a 5-lipoxygenase inhibitor (SC 45662).","1989152",40]
["(2-(2-(2,4-dioxo-1,3-thiazolidin-3-yl)ethylamino)-2-oxoethyl) 2-(furan-2-carbonylamino)acetate","(2-(2-(2,4-dioxo-1,3-thiazolidin-3-yl)ethylamino)-2-oxoethyl) 2-(furan-2-carbonylamino)acetate","C534988","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18796695","A double-headed cathepsin B inhibitor devoid of warhead.","18796695",40]
["(2-(2,6-dichlorobenzyl)thiazolo(5,4-d)pyrimidin-7-yl)-(4-trifluoromethylphenyl)amine","(2-(2,6-dichlorobenzyl)thiazolo(5,4-d)pyrimidin-7-yl)-(4-trifluoromethylphenyl)amine","C568132","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,1,2014,"24549371","Clinical and preclinical characterization of the histamine H(4) receptor antagonist JNJ-39758979.","24549371",40]
["(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane","(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane","C010654","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15755656","QSAR study for a novel series of ortho monosubstituted phenoxy analogues of alpha1-adrenoceptor antagonist WB4101.","15755656",40]
["(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane","(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane","C010654","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9634279","Capillary electrophoretic and high-performance liquid chromatographic studies of the enantioselective separation of alpha1-adrenoreceptor antagonists.","9634279",40]
["(2'-(3-benzyl-1-ethylureidomethyl)-6-methoxy-4'-trifluoromethylbiphenyl-3-yl)acetic acid","(2'-(3-benzyl-1-ethylureidomethyl)-6-methoxy-4'-trifluoromethylbiphenyl-3-yl)acetic acid","C560624","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21487069","Pharmacology of AM211, a potent and selective prostaglandin D2 receptor type 2 antagonist that is active in animal models of allergic inflammation.","21487069",40]
["(2-(4-(4-isopropoxybenzyl)-phenylamino) imidazoline)","(2-(4-(4-isopropoxybenzyl)-phenylamino) imidazoline)","C514222","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16880763","Investigation of the prostacyclin (IP) receptor antagonist RO1138452 on isolated blood vessel and platelet preparations.","16880763",40]
["(2'-(4-aminophenyl)-(2,5'-bi-1H-benzimidazol)-5-amine)","(2'-(4-aminophenyl)-(2,5'-bi-1H-benzimidazol)-5-amine)","C579147","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27840051","Ro 90-7501 inhibits PP5 through a novel, TPR-dependent mechanism.","27840051",40]
["(2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine","(2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine","C568612","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26886507","Radiosynthesis and in Vivo Evaluation of Neuropeptide Y5 Receptor (NPY5R) PET Tracers.","26886507",40]
["(2,2'-bipyridine)(octylglycinato)palladium(II) nitrate","(2,2'-bipyridine)(octylglycinato)palladium(II) nitrate","C481806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14515204","A microcalorimetry and spectroscopy study on the interaction of BSA with 2,2'-bipyridine octylglycinato palladium(II) nitrate.","14515204",40]
["(2,2'-bipyridine)(octylglycinato)palladium(II) nitrate","(2,2'-bipyridine)(octylglycinato)palladium(II) nitrate","C481806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17718596","Binding properties of a new anti-tumor component (2,2'-bipyridin octylglycinato Pd(II) nitrate) with bovine beta-lactoglobulin-A and -B.","17718596",40]
["(2,2'-bipyridyl)-3,3'-diol","(2,2'-bipyridyl)-3,3'-diol","C499984","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23404770","Unusual binding of a potential biomarker with human serum albumin.","23404770",40]
["(2,2-bis(docosyloxymethyl)propyl-5-acetamido-3,5-dideoxy-4,7,8,9-tetra-O-(sodium oxysulfonyl)glycero-alpha-galacto-2-nonulopyranosid)onate","(2,2-bis(docosyloxymethyl)propyl-5-acetamido-3,5-dideoxy-4,7,8,9-tetra-O-(sodium oxysulfonyl)glycero-alpha-galacto-2-nonulopyranosid)onate","C413863","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2003,"14582845","Mechanistic effect of NMSO3 on replication of human immunodeficiency virus.","14582845",40]
["(2,2-bis(docosyloxymethyl)propyl-5-acetamido-3,5-dideoxy-4,7,8,9-tetra-O-(sodium oxysulfonyl)glycero-alpha-galacto-2-nonulopyranosid)onate","(2,2-bis(docosyloxymethyl)propyl-5-acetamido-3,5-dideoxy-4,7,8,9-tetra-O-(sodium oxysulfonyl)glycero-alpha-galacto-2-nonulopyranosid)onate","C413863","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2005,"16143490","Polysulfated sialic acid derivatives as anti-human immunodeficiency virus.","16143490",40]
["(2,3)-5-hydroxy-6,8-dimethoxy-2,3-dimethyl-2,3-dihydro-4H-naphtho(2,3-b)-pyran-4-one","(2,3)-5-hydroxy-6,8-dimethoxy-2,3-dimethyl-2,3-dihydro-4H-naphtho(2,3-b)-pyran-4-one","C448079","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11672740","Phytotoxic naphthopyranone derivatives from the coprophilous fungus Guanomyces polythrix.","11672740",40]
["(2,4-dihydroxy-5-isopropylphenyl)-(5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl)methanone","(2,4-dihydroxy-5-isopropylphenyl)-(5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl)methanone","C552103","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21541036","Structural determination of three different series of compounds as Hsp90 inhibitors using 3D-QSAR modeling, molecular docking and molecular dynamics methods.","21541036",40]
["(2,8-dioxabicyclo(3.3.0)oct-6-yl)-N-(4-((3,4-methylenedioxyphenyl)sulfonyl-(2-methylpropyl)amino)-3-hydroxy-1-phenylbutan-2-yl) carbamate","(2,8-dioxabicyclo(3.3.0)oct-6-yl)-N-(4-((3,4-methylenedioxyphenyl)sulfonyl-(2-methylpropyl)amino)-3-hydroxy-1-phenylbutan-2-yl) carbamate","C522027","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"19910081","Some insights into mechanism for binding and drug resistance of wild type and I50V V82A and I84V mutations in HIV-1 protease with GRL-98065 inhibitor from molecular dynamic simulations.","19910081",40]
["(2-acetoxy-(2-propynyl)benzoate)exacarbonyldicobalt","(2-acetoxy-(2-propynyl)benzoate)exacarbonyldicobalt","C505098","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15954743","Stability, protein binding and thiol interaction studies on [2-acetoxy-(2-propynyl)benzoate]hexacarbonyldicobalt.","15954743",40]
["(2E,4E,6E,10E)-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid","(2E,4E,6E,10E)-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid","C487689","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2006,"16546985","NIK-333 inhibits growth of human T-cell leukemia virus type I-infected T-cell lines and adult T-cell leukemia cells in association with blockade of nuclear factor-kappaB signal pathway.","16546985",40]
["(2-fluoromethoxy-5-(5-trifluoromethyltetrazol-1-yl)benzyl)(2-phenylpiperidin-3-yl)amine","(2-fluoromethoxy-5-(5-trifluoromethyltetrazol-1-yl)benzyl)(2-phenylpiperidin-3-yl)amine","C517420","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19200949","Decreased neurokinin-1 (substance P) receptor binding in patients with panic disorder: positron emission tomographic study with [18F]SPA-RQ.","19200949",40]
["(2-fluoromethoxy-5-(5-trifluoromethyltetrazol-1-yl)benzyl)(2-phenylpiperidin-3-yl)amine","(2-fluoromethoxy-5-(5-trifluoromethyltetrazol-1-yl)benzyl)(2-phenylpiperidin-3-yl)amine","C517420","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"19854434","Comment on \"Decreased Neurokinin-1 (Substance P) Receptor Binding in Patients with Panic Disorder: Positron Emission Tomographic Study With [(18)F]SPA-RQ\".","19854434",40]
["(2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide","(2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide","C507236","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20184887","Molecular determinants of Kv1.5 channel block by diphenyl phosphine oxide-1.","20184887",40]
["(2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide","(2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide","C507236","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23260347","Synthesis and evaluation of diphenylphosphinic amides and diphenylphosphine oxides as inhibitors of Kv1.5.","23260347",40]
["(2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide","(2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide","C507236","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23717641","Potent suppression of Kv1.3 potassium channel and IL-2 secretion by diphenyl phosphine oxide-1 in human T cells.","23717641",40]
["(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine","(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine","C097591","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10728887","Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171--PET studies in rhesus monkey.","10728887",40]
["(2R)-6-methoxy-8-(4-methylpiperazin-1-yl)-N-(4-morpholin-4-ylphenyl)chromane-2-carboxamide","(2R)-6-methoxy-8-(4-methylpiperazin-1-yl)-N-(4-morpholin-4-ylphenyl)chromane-2-carboxamide","C558331","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21234549","Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369.","21234549",40]
["(2R)-6-methoxy-8-(4-methylpiperazin-1-yl)-N-(4-morpholin-4-ylphenyl)chromane-2-carboxamide","(2R)-6-methoxy-8-(4-methylpiperazin-1-yl)-N-(4-morpholin-4-ylphenyl)chromane-2-carboxamide","C558331","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21825000","Preclinical pharmacology and pharmacokinetics of AZD3783, a selective 5-hydroxytryptamine 1B receptor antagonist.","21825000",40]
["(2S)-2-(4-(((3S)-1-acetimidoyl-3-pyrrolidinyl)oxy)phenyl)-3-(7-amidino-2-naphtyl)propanoic acid","(2S)-2-(4-(((3S)-1-acetimidoyl-3-pyrrolidinyl)oxy)phenyl)-3-(7-amidino-2-naphtyl)propanoic acid","C086910","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19128974","Discovery of N-[(1R,2S,5S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride: a novel, potent and orally active direct inhibitor of factor Xa.","19128974",40]
["(2S)-2-(4-(((3S)-1-acetimidoyl-3-pyrrolidinyl)oxy)phenyl)-3-(7-amidino-2-naphtyl)propanoic acid","(2S)-2-(4-(((3S)-1-acetimidoyl-3-pyrrolidinyl)oxy)phenyl)-3-(7-amidino-2-naphtyl)propanoic acid","C086910","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9690170","Evaluation of proposed modes of binding of (2S)-2-[4-[[(3S)-1-acetimidoyl-3-pyrrolidinyl]oxy]phenyl]-3-(7-am idino- 2- naphthyl)propanoic acid hydrochloride and some analogs to factor Xa using a comparative molecular field analysis.","9690170",40]
["(2S)-2-(4-(((3S)-1-acetimidoyl-3-pyrrolidinyl)oxy)phenyl)-3-(7-amidino-2-naphtyl)propanoic acid","(2S)-2-(4-(((3S)-1-acetimidoyl-3-pyrrolidinyl)oxy)phenyl)-3-(7-amidino-2-naphtyl)propanoic acid","C086910","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2003,"12719661","Effects of DX-9065a, an inhibitor of factor Xa, on ellagic acid-induced plantar skin thrombosis assessed in tetrodotoxin- and N(omega)-nitro-L-arginine-treated rats.","12719661",40]
["(2S)-2-(4-(3-azidophenyl)-2-oxopyrrolidin-1-yl)butanamide","(2S)-2-(4-(3-azidophenyl)-2-oxopyrrolidin-1-yl)butanamide","C487592","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23530581","Modulation of the conformational state of the SV2A protein by an allosteric mechanism as evidenced by ligand binding assays.","23530581",40]
["(2S)-3-(2',5'-dichlorobiphenyl-4-yl)-2-(((1-(2-methoxybenzoyl)piperidin-3-yl)carbonyl)amino)propanoic acid","(2S)-3-(2',5'-dichlorobiphenyl-4-yl)-2-(((1-(2-methoxybenzoyl)piperidin-3-yl)carbonyl)amino)propanoic acid","C519332","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17234179","Inhibition of eosinophilia in vivo by a small molecule inhibitor of very late antigen (VLA)-4.","17234179",40]
["(3-(3,5-dimethyl-4-(3-phenylpropyl)-1-piperazinyl)propyl)diphenylamine","(3-(3,5-dimethyl-4-(3-phenylpropyl)-1-piperazinyl)propyl)diphenylamine","C400075","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10543888","Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.","10543888",40]
["(3-(4-tolylamino)-5-amino-1H-1,2,4-triazol-1-yl)(3,4,5-trimethoxyphenyl)methanone","(3-(4-tolylamino)-5-amino-1H-1,2,4-triazol-1-yl)(3,4,5-trimethoxyphenyl)methanone","C000595013","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25025853","Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.","25025853",40]
["(3,4-dihydroxyphenylamino)-2-imidazoline","(3,4-dihydroxyphenylamino)-2-imidazoline","C011775","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11278710","The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide.","11278710",40]
["(3,5,6-trimethylpyrazin-2-yl)methyl 2-(4-(2-methylpropyl)phenyl)propanoate","(3,5,6-trimethylpyrazin-2-yl)methyl 2-(4-(2-methylpropyl)phenyl)propanoate","C495410","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16545771","A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo.","16545771",40]
["(3,5,6-trimethylpyrazinyl)methyl 2-acetoxy-3-(3,4-diacetoxyphenyl)propanoate","(3,5,6-trimethylpyrazinyl)methyl 2-acetoxy-3-(3,4-diacetoxyphenyl)propanoate","C000596359","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24581174","Design, synthesis, and preliminary cardioprotective effect evaluation of danshensu derivatives.","24581174",40]
["(3,5-bis(4-fluorophenyl)tetrahydro-1H-oxazolo(3,4-c)oxazol-7a-yl)methanol","(3,5-bis(4-fluorophenyl)tetrahydro-1H-oxazolo(3,4-c)oxazol-7a-yl)methanol","C545992","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19728715","(3R,5S,7as)-(3,5-Bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol, a novel neuroprotective agent.","19728715",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C131,B131)","v":"(3,6-dimethyl-2-(2,4,6-trimethylphenoxy)pyridin-4-yl)(1-ethylpropyl)amine"},"(3,6-dimethyl-2-(2,4,6-trimethylphenoxy)pyridin-4-yl)(1-ethylpropyl)amine","C529296","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J131,K131)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2014,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q131,Q131)","v":"24820411"},"Exploration of the antagonist CP-376395 escape pathway for the corticotropin-releasing factor receptor 1 by random acceleration molecular dynamics simulations.","24820411",40]
["(3,6-dimethyl-2-(2,4,6-trimethylphenoxy)pyridin-4-yl)(1-ethylpropyl)amine","(3,6-dimethyl-2-(2,4,6-trimethylphenoxy)pyridin-4-yl)(1-ethylpropyl)amine","C529296","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25980590","An insight into antagonist binding and induced conformational dynamics of class B GPCR corticotropin-releasing factor receptor 1.","25980590",40]
["(3-aminohexahydroazepine)dichloroplatinum(II)","(3-aminohexahydroazepine)dichloroplatinum(II)","C105315","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15922304","DNA adducts of the enantiomers of the Pt(II) complexes of the ahaz ligand (ahaz=3-aminohexahydroazepine) and recognition of these adducts by HMG domain proteins.","15922304",40]
["(3-aminopropyl)(n-butyl)phosphinic acid","(3-aminopropyl)(n-butyl)phosphinic acid","C079148","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2005,"15857622","GABAB receptor antagonist SGS742 improves spatial memory and reduces protein binding to the cAMP response element (CRE) in the hippocampus.","15857622",40]
["(3aS-(3aalpha,4beta,5beta,7beta,7aalpha))-4-(octahydro-5-hydroxy-4,7-dimethyl-1,3-dioxo-4,7-epoxy-2H-isoindol-2-yl)-2-iodobenzonitrile","(3aS-(3aalpha,4beta,5beta,7beta,7aalpha))-4-(octahydro-5-hydroxy-4,7-dimethyl-1,3-dioxo-4,7-epoxy-2H-isoindol-2-yl)-2-iodobenzonitrile","C529326","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18291644","Identification and optimization of a novel series of [2.2.1]-oxabicyclo imide-based androgen receptor antagonists.","18291644",40]
["(3-dimyristyloxypropyl)(dimethyl)(hydroxyethyl)ammonium","(3-dimyristyloxypropyl)(dimethyl)(hydroxyethyl)ammonium","C087276","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1995,"8588922","Optimization of gene transfer using cationic lipids in cell lines and primary human CD4+ and CD34+ hematopoietic cells.","8588922",40]
["(3-mercaptopropyl)trimethoxysilane","(3-mercaptopropyl)trimethoxysilane","C102833","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2015,"26269007","Occupational contact dermatitis caused by (3-mercaptopropyl)trimethoxysilane in a windscreen repairer.","26269007",40]
["(3-mercaptopropyl)trimethoxysilane","(3-mercaptopropyl)trimethoxysilane","C102833","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20417071","Size-controlled synthesis, surface functionalization, and biological applications of thiol-organosilica particles.","20417071",40]
["(3-mercaptopropyl)trimethoxysilane","(3-mercaptopropyl)trimethoxysilane","C102833","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28427269","Spatially selective binding of green fluorescent protein on designed organosilane nanopatterns prepared with particle lithography.","28427269",40]
["(3-phenyl-2-isoxazoline-5-yl)phosphonic acid","(3-phenyl-2-isoxazoline-5-yl)phosphonic acid","C072866","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1991,"1783467","Effect of the new immunostimulator HAB 439 on cell-mediated immunity against intracellular bacteria.","1783467",40]
["(3R)-3-amino-N-(4-(4-phenylthiazol-2-yl)-tetrahydro-2H-thiopyran-4-yl)-4-(2,4,5-trifluorophenyl)butanamide 1,1-dioxide","(3R)-3-amino-N-(4-(4-phenylthiazol-2-yl)-tetrahydro-2H-thiopyran-4-yl)-4-(2,4,5-trifluorophenyl)butanamide 1,1-dioxide","C579642","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"23072865","Novel series of 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides as potent and selective dipeptidyl peptidase IV inhibitors.","23072865",40]
["(3S)-3-(((2S)-2-(4,4-dimethyl-3-(4-((((2-methylphenyl)amino)carbonyl)amino)benzyl)-2,5-dioxoimidazolidin-1-yl)-4-methylpentanoyl)amino)-3-phenylpropanoic acid","(3S)-3-(((2S)-2-(4,4-dimethyl-3-(4-((((2-methylphenyl)amino)carbonyl)amino)benzyl)-2,5-dioxoimidazolidin-1-yl)-4-methylpentanoyl)amino)-3-phenylpropanoic acid","C483465","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15098200","Critical period for a teratogenic VLA-4 antagonist: Developmental effects and comparison of embryo drug concentrations of teratogenic and non-teratogenic VLA-4 antagonists.","15098200",40]
["(4-((1R, 2S, 3R, 5R)-5-Chloro-2-((S)-3-cyclohexyl-3-hydroxyprop-1-ynyl)-3-hydroxycyclopentyl) butylthio) acetic acid monohydrate","(4-((1R, 2S, 3R, 5R)-5-Chloro-2-((S)-3-cyclohexyl-3-hydroxyprop-1-ynyl)-3-hydroxycyclopentyl) butylthio) acetic acid monohydrate","C518544","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"17328887","The anti-pruritic efficacy of TS-022, a prostanoid DP1 receptor agonist, is dependent on the endogenous prostaglandin D2 level in the skin of NC/Nga mice.","17328887",40]
["(4-((1R, 2S, 3R, 5R)-5-Chloro-2-((S)-3-cyclohexyl-3-hydroxyprop-1-ynyl)-3-hydroxycyclopentyl) butylthio) acetic acid monohydrate","(4-((1R, 2S, 3R, 5R)-5-Chloro-2-((S)-3-cyclohexyl-3-hydroxyprop-1-ynyl)-3-hydroxycyclopentyl) butylthio) acetic acid monohydrate","C518544","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"17141215","Effects of TS-022, a newly developed prostanoid DP1 receptor agonist, on experimental pruritus, cutaneous barrier disruptions and atopic dermatitis in mice.","17141215",40]
["(4-(2-(3,5-bis(ethoxycarbonyloxy)phenyl)vinyl)phenyl) ethyl carbonate","(4-(2-(3,5-bis(ethoxycarbonyloxy)phenyl)vinyl)phenyl) ethyl carbonate","C000608951","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2016,"26851025","Antiproliferative and Pro-apoptotic Activities of a Novel Resveratrol Prodrug Against Jurkat CD4+ T-Cells.","26851025",40]
["(4-(4-(4-carbamimidoylphenyl)-3-oxopiperazin-1-yl)piperidino)acetic acid monohydrochloride trihydrate","(4-(4-(4-carbamimidoylphenyl)-3-oxopiperazin-1-yl)piperidino)acetic acid monohydrochloride trihydrate","C462000","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2002,"11937091","Pharmacological properties of YM-57029, a novel platelet glycoprotein IIb/IIIa antagonist.","11937091",40]
["(4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid","(4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid","C461658","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2008,"18930112","Complex actions of thyroid hormone receptor antagonist NH-3 on gene promoters in different cell lines.","18930112",40]
["(4-(6-chloro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)butyl) 1-phosphate","(4-(6-chloro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)butyl) 1-phosphate","C515409","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16984393","Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis.","16984393",40]
["(4-(carbamimidoylsulfanylmethyl)-2,5-dimethylphenyl)methylsulfanylmethanimidamide","(4-(carbamimidoylsulfanylmethyl)-2,5-dimethylphenyl)methylsulfanylmethanimidamide","C547922","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19159012","Discovery of a non-peptidic inhibitor of west nile virus NS3 protease by high-throughput docking.","19159012",40]
["(4-(dimethylamino)phenyl)(5-iodobenzofuran-2-yl)methanone","(4-(dimethylamino)phenyl)(5-iodobenzofuran-2-yl)methanone","C561764","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21622003","Synthesis and evaluation of benzofuran-2-yl(phenyl)methanone derivatives as ligands for β-amyloid plaques.","21622003",40]
["(4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride","(4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride","D008455","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20643905","Mutagenesis of nucleophilic residues near the orthosteric binding pocket of M1 and M2 muscarinic receptors: effect on the binding of nitrogen mustard analogs of acetylcholine and McN-A-343.","20643905",40]
["(4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo(6.6.2)hexadecane)copper(II)","(4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo(6.6.2)hexadecane)copper(II)","C483895","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19397856","Evaluation of [64Cu]Cu-DOTA and [64Cu]Cu-CB-TE2A chelates for targeted positron emission tomography with an alphavbeta6-specific peptide.","19397856",40]
["(4-aminomethyl)phenylazobenzoic acid","(4-aminomethyl)phenylazobenzoic acid","C417555","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15637699","Photomodulation of conformational states. IV. Integrin-binding RGD-peptides with (4-aminomethyl)phenylazobenzoic acid as backbone constituent.","15637699",40]
["(4-benzylpiperazin-1-yl)acetic acid (3-allyl-2-hydroxybenzylidene)hydrazine","(4-benzylpiperazin-1-yl)acetic acid (3-allyl-2-hydroxybenzylidene)hydrazine","C514579","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20143368","Activation instead of inhibition: targeting proenzymes for small-molecule intervention.","20143368",40]
["(4-chloro-2-((2-fluoro-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","(4-chloro-2-((2-fluoro-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","C568958","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2011,"21916510","Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.","21916510",40]
["(4-chloro-2-((2-fluoro-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","(4-chloro-2-((2-fluoro-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","C568958","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21916510","Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.","21916510",40]
["(4-chloro-2-((2-methyl-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","(4-chloro-2-((2-methyl-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","C568957","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2011,"21916510","Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.","21916510",40]
["(4-chloro-2-((2-methyl-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","(4-chloro-2-((2-methyl-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid","C568957","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21916510","Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.","21916510",40]
["(4-cyclobutyl-(1,4)diazepan-1-yl)-(6-(4-fluorophenoxy)pyridin-3-yl)methanone","(4-cyclobutyl-(1,4)diazepan-1-yl)-(6-(4-fluorophenoxy)pyridin-3-yl)methanone","C559587","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21086115","JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.","21086115",40]
["(4-iodobutyl)triphenylphosphonium","(4-iodobutyl)triphenylphosphonium","C456341","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11861642","Specific modification of mitochondrial protein thiols in response to oxidative stress: a proteomics approach.","11861642",40]
["(4-methoxybenzylthio)-6-(3-chlorobenzoyl)-5-methylpyrimidin-4(3H)-one","(4-methoxybenzylthio)-6-(3-chlorobenzoyl)-5-methylpyrimidin-4(3H)-one","C588115","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24055077","Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: synthesis, biological investigation and molecular modeling studies.","24055077",40]
["(4-methoxyphenyl)methyl isobutyrate","(4-methoxyphenyl)methyl isobutyrate","C577701","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22406564","Fragrance material review on (4-methoxyphenyl)methyl isobutyrate.","22406564",40]
["(4-nitrophenyl)vinyl ether","(4-nitrophenyl)vinyl ether","C047678","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11401574","Binding and oxidation of alkyl 4-nitrophenyl ethers by rabbit cytochrome P450 1A2: evidence for two binding sites.","11401574",40]
["(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","C546624","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2014,"25307040","Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection.","25307040",40]
["(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","C546624","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2016,"27128484","mTOR Inhibition Attenuates Dextran Sulfate Sodium-Induced Colitis by Suppressing T Cell Proliferation and Balancing TH1/TH17/Treg Profile.","27128484",40]
["(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","C546624","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2011,"21540234","mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment.","21540234",40]
["(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","C546624","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2014,"25307040","Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection.","25307040",40]
["(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","C546624","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2016,"27128484","mTOR Inhibition Attenuates Dextran Sulfate Sodium-Induced Colitis by Suppressing T Cell Proliferation and Balancing TH1/TH17/Treg Profile.","27128484",40]
["(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","C546624","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"21540234","mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment.","21540234",40]
["(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol","C546624","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27980105","The mTORC1/2 Inhibitor AZD8055 Strengthens the Efficiency of the MEK Inhibitor Trametinib to Reduce the Mcl-1/[Bim and Puma] ratio and to Sensitize Ovarian Carcinoma Cells to ABT-737.","27980105",40]
["(5-(benzyloxy)-1H-indol-1-yl)acetic acid","(5-(benzyloxy)-1H-indol-1-yl)acetic acid","C000609325","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26345091","[5-(Benzyloxy)-1H-indol-1-yl]acetic acid, an aldose reductase inhibitor and PPARγ ligand.","26345091",40]
["(5-(p-fluorophenyl)-2-ureido)thiophene-3-carboxamide","(5-(p-fluorophenyl)-2-ureido)thiophene-3-carboxamide","C586469","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,2013,"23667871","Effect of IKK-2 inhibitor on local Th1 and Th2 type inflammation.","23667871",40]
["(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride","(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride","C439285","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14581372","Exisulind and related compounds inhibit expression and function of the androgen receptor in human prostate cancer cells.","14581372",40]
["(5-methoxy)donepezil","(5-methoxy)donepezil","C473648","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19286462","Quantitative analysis of donepezil binding to acetylcholinesterase using positron emission tomography and [5-(11)C-methoxy]donepezil.","19286462",40]
["(5-oxo-5,6-dihydroindolo(1,2-a)quinazolin-7-yl)acetic acid","(5-oxo-5,6-dihydroindolo(1,2-a)quinazolin-7-yl)acetic acid","C475515","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12801229","Discovery of a potent and selective protein kinase CK2 inhibitor by high-throughput docking.","12801229",40]
["(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo(4,5-b)pyridin-1-yl)piperidine-1-carboxylate","(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo(4,5-b)pyridin-1-yl)piperidine-1-carboxylate","C578443","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28192258","Binding and functional pharmacological characteristics of gepant-type antagonists in rat brain and mesenteric arteries.","28192258",40]
["(5Z)-7-((1R,2R, 3R,5S)-2-((1E)-3,3-difluoro-4-phenoxy -1-butenyl)-3,5-dihydroxycyclopentyl)-5-heptenoic acid","(5Z)-7-((1R,2R, 3R,5S)-2-((1E)-3,3-difluoro-4-phenoxy -1-butenyl)-3,5-dihydroxycyclopentyl)-5-heptenoic acid","C485334","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15037111","Pharmacological characteristics of AFP-168 (tafluprost), a new prostanoid FP receptor agonist, as an ocular hypotensive drug.","15037111",40]
["(6-((4'-(2-ethoxyethoxy)-2',6'-dimethylbiphenyl-3-yl)methoxy)-2,3-dihydro-1-benzofuran-3-yl)acetic acid","(6-((4'-(2-ethoxyethoxy)-2',6'-dimethylbiphenyl-3-yl)methoxy)-2,3-dihydro-1-benzofuran-3-yl)acetic acid","C572349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22242551","Identification of fused-ring alkanoic acids with improved pharmacokinetic profiles that act as G protein-coupled receptor 40/free fatty acid receptor 1 agonists.","22242551",40]
["(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","C516138","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2012,"22144105","Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T-cell activation and differentiation.","22144105",40]
["(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","C516138","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23639540","Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probe.","23639540",40]
["(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","C516138","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25368322","Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation.","25368322",40]
["(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","C516138","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2016,"27177226","AMPK-dependent and independent effects of AICAR and compound C on T-cell responses.","27177226",40]
["(6-(4-(morpholinoformimidoyl)benzamido)-3,4-dihydro-2H-1-benzopyran-3-yl)acetic acid","(6-(4-(morpholinoformimidoyl)benzamido)-3,4-dihydro-2H-1-benzopyran-3-yl)acetic acid","C119462","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1999,"10079002","Antiaggregatory, antithrombotic effects of MS-180, a novel platelet glycoprotein IIb/IIIa receptor antagonist.","10079002",40]
["(6-bromo-1-(4-fluorophenylmethyl)-4(1H)-quinolinon-3-yl)-4-hydroxy-2-oxo-3-butenoic acid","(6-bromo-1-(4-fluorophenylmethyl)-4(1H)-quinolinon-3-yl)-4-hydroxy-2-oxo-3-butenoic acid","C543995","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19556126","Structural and theoretical studies of [6-bromo-1-(4-fluorophenylmethyl)-4(1H)-quinolinon-3-yl)]-4-hydroxy-2-oxo-3-butenoïc acid as HIV-1 integrase inhibitor.","19556126",40]
["(7-(2-((1,1'-biphenyl)-4-ylmethylene)hydrazinyl)-N-hydroxy-7-oxoheptanamide)","(7-(2-((1,1'-biphenyl)-4-ylmethylene)hydrazinyl)-N-hydroxy-7-oxoheptanamide)","C578174","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26804233","Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation.","26804233",40]
["(7-(2-(4-difluorophenyl)-1-piperazinyl)ethyl)-2-(2-furanyl)-7H-pyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-amine","(7-(2-(4-difluorophenyl)-1-piperazinyl)ethyl)-2-(2-furanyl)-7H-pyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-amine","C534887","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24486705","Effects of the selective adenosine A2A receptor antagonist, SCH 412348, on the parkinsonian phenotype of MitoPark mice.","24486705",40]
["(7-(2,6-dichlorophenyl)-5-methylbenzo(1,2,4)triazin-3-yl)-(4-(2-pyrrolidin-1-ylethoxy)phenyl)amine","(7-(2,6-dichlorophenyl)-5-methylbenzo(1,2,4)triazin-3-yl)-(4-(2-pyrrolidin-1-ylethoxy)phenyl)amine","C522499","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17113292","Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine--a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays.","17113292",40]
["(8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro(4.5)dec-3-yl)-acetic acid","(8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro(4.5)dec-3-yl)-acetic acid","C498149","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15054115","DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted mu opioid agonist with antihyperalgesic activity: I. In vitro pharmacological characterization and pharmacokinetic properties.","15054115",40]
["(90)Y-2,3-dicarboxypropane-1,1-diphosphonic acid","(90)Y-2,3-dicarboxypropane-1,1-diphosphonic acid","C528986","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18331797","Labeling, characterization, and in vivo localization of a new 90Y-based phosphonate chelate 2,3-dicarboxypropane-1,1-diphosphonic acid for the treatment of bone metastases: Comparison with 99mTc-DPD complex.","18331797",40]
["(9H-purin-6-yl)thiomethyl glutamate","(9H-purin-6-yl)thiomethyl glutamate","C108537","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1997,"9285248","Study on the mechanism of immunopotentiating antitumor effect of 6-MPG, a water-soluble derivative of 6-mercaptopurine.","9285248",40]
["(all-E) phytoene","(all-E) phytoene","C100185","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2005,"15830922","Supplementation with tomato-based products increases lycopene, phytofluene, and phytoene levels in human serum and protects against UV-light-induced erythema.","15830922",40]
["(bisindazole)tetrachlororuthenate(III)","(bisindazole)tetrachlororuthenate(III)","C415339","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10857915","Studies on the interactions between human serum albumin and trans-indazolium (bisindazole) tetrachlororuthenate(III).","10857915",40]
["(bromoacetyl)trichodermin","(bromoacetyl)trichodermin","C047812","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"3936536","Affinity labeling the ribosome with eukaryotic-specific antibiotics: (bromoacetyl)trichodermin.","3936536",40]
["(butyldithiocarbamate)(1,10-phenanthroline)palladium(II)","(butyldithiocarbamate)(1,10-phenanthroline)palladium(II)","C000599717","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25513861","Investigation of the interaction between human serum albumin and antitumor palladium(II) complex containing 1,10-phenanthroline and dithiocarbamate ligands.","25513861",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C195,B195)","v":"(E)-1-(2-nitrovinyl)naphthalene"},"(E)-1-(2-nitrovinyl)naphthalene","C000599592","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J195,K195)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2015,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q195,Q195)","v":"25795708"},"Nitrostyrene Derivatives Act as RXRα Ligands to Inhibit TNFα Activation of NF-κB.","25795708",40]
["(E)-2-isopropyl-5-methylcyclohexyl octadec-9-enoate","(E)-2-isopropyl-5-methylcyclohexyl octadec-9-enoate","C559968","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21054218","Effect of (E)-2-isopropyl-5-methylcyclohexyl octadec-9-enoate on transdermal delivery of Aconitum alkaloids.","21054218",40]
["(E)-3-((((6-(2-carboxyethenyl)-5-((8-(4-methoxyphenyl)octyl)oxy)-2-pyridinyl)methyl)thio)methyl)benzoic acid","(E)-3-((((6-(2-carboxyethenyl)-5-((8-(4-methoxyphenyl)octyl)oxy)-2-pyridinyl)methyl)thio)methyl)benzoic acid","C083427","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1999,"10477044","In vitro and in vivo pharmacological characterization of SB 201993, an eicosanoid-like LTB4 receptor antagonist with anti-inflammatory activity.","10477044",40]
["(E)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one","(E)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one","C570750","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20866106","Chemical basis for the extreme skin sensitization potency of (E)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one.","20866106",40]
["(E)-4-carboxystyryl-4-chlorobenzylsulfone, sodium salt","(E)-4-carboxystyryl-4-chlorobenzylsulfone, sodium salt","C520364","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21341279","Effects of formulation and route of administration on the systemic availability of Ex-RAD®, a new radioprotectant, in preclinical species.","21341279",40]
["(E)-4-carboxystyryl-4-chlorobenzylsulfone, sodium salt","(E)-4-carboxystyryl-4-chlorobenzylsulfone, sodium salt","C520364","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23212688","Disposition of ON 01210.Na (Ex-RAD(R)), a novel radioprotectant, in the isolated perfused rat liver: probing metabolic inhibition to increase systemic exposure.","23212688",40]
["(E)-4-hydroxy-3-methylbut-2-enyl diphosphate","(E)-4-hydroxy-3-methylbut-2-enyl diphosphate","C547602","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24188825","Structure of the (E)-4-hydroxy-3-methyl-but-2-enyl-diphosphate reductase from Plasmodium falciparum.","24188825",40]
["(E)-4-hydroxy-3-methylbut-2-enyl diphosphate","(E)-4-hydroxy-3-methylbut-2-enyl diphosphate","C547602","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28631855","A Photo-Crosslinkable Biotin Derivative of the Phosphoantigen (E)-4-Hydroxy-3-Methylbut-2-Enyl Diphosphate (HMBPP) Activates Vγ9Vδ2 T Cells and Binds to the HMBPP Site of BTN3A1.","28631855",40]
["(E)-4-hydroxy-3-methylbut-2-enyl diphosphate","(E)-4-hydroxy-3-methylbut-2-enyl diphosphate","C547602","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2017,"28631855","A Photo-Crosslinkable Biotin Derivative of the Phosphoantigen (E)-4-Hydroxy-3-Methylbut-2-Enyl Diphosphate (HMBPP) Activates Vγ9Vδ2 T Cells and Binds to the HMBPP Site of BTN3A1.","28631855",40]
["(E)-9-(2-nitrovinyl)anthracene","(E)-9-(2-nitrovinyl)anthracene","C000599593","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25795708","Nitrostyrene Derivatives Act as RXRα Ligands to Inhibit TNFα Activation of NF-κB.","25795708",40]
["(E)-N-(3-iodoprop-2-enyl)-2beta-carbofluoroethoxy-3beta-(4'-methyl-phenyl) nortropane","(E)-N-(3-iodoprop-2-enyl)-2beta-carbofluoroethoxy-3beta-(4'-methyl-phenyl) nortropane","C543996","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19562698","In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand.","19562698",40]
["(E)-N-(3-iodoprop-2-enyl)-2beta-carbofluoroethoxy-3beta-(4'-methyl-phenyl) nortropane","(E)-N-(3-iodoprop-2-enyl)-2beta-carbofluoroethoxy-3beta-(4'-methyl-phenyl) nortropane","C543996","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25791993","Quantitative Analysis of ¹⁸F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease.","25791993",40]
["(E,E)-1-fluoro-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene","(E,E)-1-fluoro-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene","C496440","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19161320","A versatile approach to beta-amyloid fibril-binding compounds exploiting the Shirakawa/Hayashi protocol for trans-alkene synthesis.","19161320",40]
["(E,E)-2-(benzylaminocarbonyl)-3-styrylacrylonitrile","(E,E)-2-(benzylaminocarbonyl)-3-styrylacrylonitrile","C583879","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23220642","Novel soluble myeloid cell leukemia sequence 1 (Mcl-1) inhibitor (E,E)-2-(benzylaminocarbonyl)-3-styrylacrylonitrile (4g) developed using a fragment-based approach.","23220642",40]
["(IR,2R)-2-(4'-(3-phenyl-ureido)-biphenyl-4-carbonyl)cyclopentanecarboxylic acid","(IR,2R)-2-(4'-(3-phenyl-ureido)-biphenyl-4-carbonyl)cyclopentanecarboxylic acid","C542909","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"25405858","Intestine-targeted DGAT1 inhibition improves obesity and insulin resistance without skin aberrations in mice.","25405858",40]
["(methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine","(methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine","C526315","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23148296","Propofol decreases in vivo binding of 11C-PBR28 to translocator protein (18 kDa) in the human brain.","23148296",40]
["(methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine","(methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine","C526315","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2015,"25487553","Comparison of standardized uptake values with volume of distribution for quantitation of [(11)C]PBR28 brain uptake.","25487553",40]
["(methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine","(methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine","C526315","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25766898","Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein.","25766898",40]
["(methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine","(methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine","C526315","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26293827","Test-retest reproducibility of [(11)C]PBR28 binding to TSPO in healthy control subjects.","26293827",40]
["(methyl)bis(tallow amidoethyl)(2-hydroxyethyl)ammonium methyl sulfate","(methyl)bis(tallow amidoethyl)(2-hydroxyethyl)ammonium methyl sulfate","C093205","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1995,"7731528","The use of fabric softener in neurosurgical prosections.","7731528",40]
["(N)1-acetylisoniazid","(N)1-acetylisoniazid","C006377","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3408638","Saliva and plasma concentrations of isoniazid and acetylisoniazid in man.","3408638",40]
["(N)1-acetylisoniazid","(N)1-acetylisoniazid","C006377","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3580961","Effect of rifampin, phenobarbital pretreatment, and acetylator phenotype on acetylisoniazid metabolism in the rabbit.","3580961",40]
["(N,N-dimethylcarbamoyl)-4-amino-4'-chlorostilbene","(N,N-dimethylcarbamoyl)-4-amino-4'-chlorostilbene","C065243","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2116126","Molecular modelling studies on the binding of phenylurea inhibitors to the D 1 protein of photosystem II.","2116126",40]
["(N1-(7-chloro-quinolin-4yl)-3-(N3,N3-diethylamino)propylamine) dihydrochloride trihydrate","(N1-(7-chloro-quinolin-4yl)-3-(N3,N3-diethylamino)propylamine) dihydrochloride trihydrate","C434089","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15204721","Pharmacokinetics of the antimalarial drug, AQ-13, in rats and cynomolgus macaques.","15204721",40]
["(N-2-amino-N-2-methylamino-2,2,1-bicycloheptane)dichloroplatinum(II)","(N-2-amino-N-2-methylamino-2,2,1-bicycloheptane)dichloroplatinum(II)","C095675","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7673159","Binding of the Escherichia coli UvrAB proteins to the DNA mono- and diadducts of cis-[N-2-amino-N-2-methylamino-2,2,1-bicycloheptane]dichloroplatinum(II ) and cisplatin. Analysis of the factors controlling recognition and proof of monoadduct-mediated UvrB-DNA cross-linking.","7673159",40]
["(N-benzoyl)-5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-N-4-azidobenzoylpentylamine","(N-benzoyl)-5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-N-4-azidobenzoylpentylamine","C060845","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2569930","Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells.","2569930",40]
["(N-MeCys(3)-N-MeCys(7))TANDEM","(N-MeCys(3)-N-MeCys(7))TANDEM","C075619","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8448108","Solution structure of a complex between [N-MeCys3,N-MeCys7]TANDEM and [d(GATATC)]2.","8448108",40]
["(polyethylene glycol methyl ether methacrylate)-block-poly(methyl methacrylate)","(polyethylene glycol methyl ether methacrylate)-block-poly(methyl methacrylate)","C000613815","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26788555","Oseltamivir-conjugated polymeric micelles prepared by RAFT living radical polymerization as a new active tumor targeting drug delivery platform.","26788555",40]
["(polyethylene-acrylic acid) copolymer","(polyethylene-acrylic acid) copolymer","C083316","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2001,"11205394","Optician's occupational allergic contact dermatitis, paresthesia and paronychia caused by anaerobic acrylic sealants.","11205394",40]
["(R)-(11C)1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide","(R)-(11C)1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide","C504060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23715902","[¹¹C]-(R)PK11195 tracer kinetics in the brain of glioma patients and a comparison of two referencing approaches.","23715902",40]
["(R)-2,3-epoxypropyl (1-3)-beta-D-pentaglucoside","(R)-2,3-epoxypropyl (1-3)-beta-D-pentaglucoside","C499691","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15546722","Synthesis, (1--&gt;3)-beta-D-glucanase-binding ability and phytoalexin-elicitor activity of (R)-2,3-epoxypropyl (1--&gt;3)-beta-D-pentaglucoside.","15546722",40]
["(R)-3-(2-chloro-1-hydroxyethyl)phenol","(R)-3-(2-chloro-1-hydroxyethyl)phenol","C580893","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2012,"23151194","Occupational allergic contact dermatitis caused by (R)-3-(2-chloro-1-hydroxyethyl)-phenol.","23151194",40]
["(R)-3-(cyclopentylmethyl)-4-(cyclopropyl-(4-(2,6-dichlorophenyl)thiazol-2-yl)amino)-4-oxobutanoic acid","(R)-3-(cyclopentylmethyl)-4-(cyclopropyl-(4-(2,6-dichlorophenyl)thiazol-2-yl)amino)-4-oxobutanoic acid","C582956","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23589301","Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor.","23589301",40]
["(S)-(1-azabicyclo(2.2.2)oct-3-yl)carbamic acid (S)-1-(2-fluorophenyl) ethyl ester","(S)-(1-azabicyclo(2.2.2)oct-3-yl)carbamic acid (S)-1-(2-fluorophenyl) ethyl ester","C520400","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24164482","Differential pharmacological activity of JN403 between α7 and muscle nicotinic acetylcholine receptors.","24164482",40]
["(S)-1-((S)-2-amino-3-(4-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)phenyl)propanoyl)pyrrolidine-2-carbonitrile hydrochloride","(S)-1-((S)-2-amino-3-(4-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)phenyl)propanoyl)pyrrolidine-2-carbonitrile hydrochloride","C587123","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23932071","Exploration of N-(2-aminoethyl)piperidine-4-carboxamide as a potential scaffold for development of VEGFR-2, ERK-2 and Abl-1 multikinase inhibitor.","23932071",40]
["(S)-1-(4-methyl-1-(2-pyrimidinyl)-4-piperidylamino)acetyl-2-pyrrolidinecarbonitrile","(S)-1-(4-methyl-1-(2-pyrimidinyl)-4-piperidylamino)acetyl-2-pyrrolidinecarbonitrile","C494668","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14985056","K579, a slow-binding inhibitor of dipeptidyl peptidase IV, is a long-acting hypoglycemic agent.","14985056",40]
["(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","C509974","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2006,"16299543","NK026680, a novel compound suppressive of dendritic cell function, ameliorates mortality in acute lethal graft-versus-host reaction in mice.","16299543",40]
["(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","C509974","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2006,"17075885","NK026680, a novel suppressant of dendritic cell function, prevents the development of rapidly progressive glomerulonephritis and perinuclear antineutrophil cytoplasmic antibody in SCG/Kj mice.","17075885",40]
["(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","C509974","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2007,"17700168","A novel chemical compound, NK026680, targets dendritic cells to prolong recipient survival after rat liver grafting.","17700168",40]
["(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","C509974","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2012,"22019622","NK026680 inhibits T-cell function in an IL-2-dependent manner and prolongs cardiac allograft survival in rats.","22019622",40]
["(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","C509974","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2012,"22643332","Dendritic cells conditioned with NK026680 prolong cardiac allograft survival in mice.","22643332",40]
["(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","C509974","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17700168","A novel chemical compound, NK026680, targets dendritic cells to prolong recipient survival after rat liver grafting.","17700168",40]
["(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","(S)-1-(5-hydroxy-1,5-dimethylhexyl)-3-(7-(4-methoxyphenyl)-(1,2,4-triazolo(1,5-a)pyrimidin-2-yl))urea","C509974","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22019622","NK026680 inhibits T-cell function in an IL-2-dependent manner and prolongs cardiac allograft survival in rats.","22019622",40]
["(S)-2-(3,4-dimethoxyphenyl)-1-(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)propan-1-one","(S)-2-(3,4-dimethoxyphenyl)-1-(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)propan-1-one","C578797","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"23186287","Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis.","23186287",40]
["(S)-2-amino-5-((R)-1-(carboxymethylamino)-3-((E)-3-(4-hydroxyphenyl)allylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic acid","(S)-2-amino-5-((R)-1-(carboxymethylamino)-3-((E)-3-(4-hydroxyphenyl)allylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic acid","C555470","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20843530","Sulfur-containing constituents and one 1H-pyrrole-2-carboxylic acid derivative from pineapple [Ananas comosus (L.) Merr.] fruit.","20843530",40]
["(S)-2-amino-5-((R)-1-carboxy-2-((E)-3-(4-hydroxy-3-methoxyphenyl)allylthio)ethyl-amino)-5-oxopentanoic acid","(S)-2-amino-5-((R)-1-carboxy-2-((E)-3-(4-hydroxy-3-methoxyphenyl)allylthio)ethyl-amino)-5-oxopentanoic acid","C555469","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20843530","Sulfur-containing constituents and one 1H-pyrrole-2-carboxylic acid derivative from pineapple [Ananas comosus (L.) Merr.] fruit.","20843530",40]
["(S)-4'-((5-((1-(4-nitrophenyl)ethyl)carbamoyl)-1H-indol-1-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid","(S)-4'-((5-((1-(4-nitrophenyl)ethyl)carbamoyl)-1H-indol-1-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid","C561901","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"28025495","CHARMM Force Field Parameterization of Peroxisome Proliferator-Activated Receptor γ Ligands.","28025495",40]
["(S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido)ethyl) benzoic acid","(S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido)ethyl) benzoic acid","C523467","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18155068","In vitro pharmacological characterization of CJ-042794, a novel, potent, and selective prostaglandin EP(4) receptor antagonist.","18155068",40]
["(Z)-5-(2,4-dihydroxybenzylidene)thiazolidine-2,4-dione","(Z)-5-(2,4-dihydroxybenzylidene)thiazolidine-2,4-dione","C585780","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27242917","(Z)-5-(2,4-Dihydroxybenzylidene)thiazolidine-2,4-dione Prevents UVB-Induced Melanogenesis and Wrinkle Formation through Suppressing Oxidative Stress in HRM-2 Hairless Mice.","27242917",40]
["(Z)-5-(2,4-dihydroxybenzylidene)thiazolidine-2,4-dione","(Z)-5-(2,4-dihydroxybenzylidene)thiazolidine-2,4-dione","C585780","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27980392","Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentation.","27980392",40]
["1 alpha-(hydroxymethyl)-25-hydroxyvitamin D3","1 alpha-(hydroxymethyl)-25-hydroxyvitamin D3","C076210","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1992,"1324319","New vitamin D3 derivatives with unexpected antiproliferative activity: 1-(hydroxymethyl)-25-hydroxyvitamin D3 homologs.","1324319",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2002,"12579950","[1 alpha, 25-dihydroxyvitamin D3 and its analogues modulate the phagocytosis of human monocyte-derived dendritic cells].","12579950",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2001,"11358728","The safety of calcitriol 3 microg/g ointment. Evaluation of cutaneous contact sensitization, cumulative irritancy, photoallergic contact sensitization and phototoxicity.","11358728",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"16302563","Tolerance to calcitriol and tacalcitol in three patients with allergic contact dermatitis to calcipotriol.","16302563",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"8706417","Allergic contact dermatitis from tacalcitol.","8706417",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1997,"9412768","Delayed-type reactivity to calcipotriol without cross-sensitization to tacalcitol.","9412768",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1997,"9412768","Delayed-type reactivity to calcipotriol without cross-sensitization to tacalcitol.","9412768",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1999,"10420137","Influence of tacalcitol on cell cycle kinetics of human keratinocytes following standardized injury.","10420137",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2001,"11464105","Tacalcitol, an active vitamin D3, induces nerve growth factor production in human epidermal keratinocytes.","11464105",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2003,"12615360","Similarly potent action of 1,25-dihydroxyvitamin D3 and its analogues, tacalcitol, calcipotriol, and maxacalcitol on normal human keratinocyte proliferation and differentiation.","12615360",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2005,"16116820","Profile of clinical efficacy and safety of topical tacalcitol.","16116820",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1990,"2094749","1 alpha,24R-dihydroxyvitamin D3 has an ability comparable to that of 1 alpha,25-dihydroxyvitamin D3 to induce keratinocyte differentiation.","2094749",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1990,"2158504","Effect of 1,24R-dihydroxyvitamin D3 on the growth of human keratinocytes.","2158504",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1990,"2162363","1,24(R)-dihydroxyvitamin D3, a novel active form of vitamin D3 with high activity for inducing epidermal differentiation but decreased hypercalcemic activity.","2162363",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C259,B259)","v":"1 alpha,24-dihydroxyvitamin D3"},"1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J259,K259)","v":"Keratinocytes"},"D015603","Keratinocytes",1,3,1996,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q259,Q259)","v":"8818193"},"Effect of 1,24-dihydroxyvitamin D3 on proliferation stimulated by epidermal growth factor in cultured mouse epidermal keratinocytes.","8818193",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1996,"8967791","In vivo microautoradiography of [3H]1,24(OH)2D3 (tacalcitol) following topical application to normal rats and in vitro metabolism in human keratinocytes.","8967791",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1998,"9536224","RANTES expression in psoriatic skin, and regulation of RANTES and IL-8 production in cultured epidermal keratinocytes by active vitamin D3 (tacalcitol).","9536224",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1998,"9745143","Vitamin D3 and its synthetic analogue secocholestra-trien-1,2, 24-triol influence the metabolism and the isomerization of retinoic acid in human keratinocytes.","9745143",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1998,"9892963","1alpha,24-dihydroxyvitamin D3 (tacalcitol) is effective against Hailey-Hailey disease both in vivo and in vitro.","9892963",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1997,"9489947","An experimental pilot study of tacalcitol activities during modulation of parakeratotic skin features.","9489947",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9723955","Regulation of RANTES and IL-8 production in normal human dermal fibroblasts by active vitamin D3 (tacalcitol).","9723955",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2010,"20163421","1,24-Dihydroxyvitamin D₃ (tacalcitol) prevents skin T-cell infiltration.","20163421",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2560867","[1,25-Dihydroxyvitamin D3 receptors in lymphocytes and T- and B-lymphocyte count in patients with glomerulonephritis].","2560867",40]
["1 alpha,24-dihydroxyvitamin D3","1 alpha,24-dihydroxyvitamin D3","C023850","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"3872658","1,25-Dihydroxyvitamin D3 and 1,24-dihydroxyvitamin D3 suppress in vitro antibody response to T cell-dependent antigen.","3872658",40]
["1 alpha-acetyldinormethadol","1 alpha-acetyldinormethadol","C020700","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6138224","Uptake of l-alpha-acetylmethadol (LAAM) and its analgesically active metabolites, nor-LAAM and dinor-LAAM, in the isolated perfused rat lung.","6138224",40]
["1 alpha-hydroxyergocalciferol","1 alpha-hydroxyergocalciferol","C042533","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2006,"16516540","Evidence for the activation of 1alpha-hydroxyvitamin D2 by 25-hydroxyvitamin D-24-hydroxylase: delineation of pathways involving 1alpha,24-dihydroxyvitamin D2 and 1alpha,25-dihydroxyvitamin D2.","16516540",40]
["1-(((2-((5-cyanopyridin-2-yl)amino)ethyl)amino)acetyl)-2-cyano-(S)-pyrrolidine","1-(((2-((5-cyanopyridin-2-yl)amino)ethyl)amino)acetyl)-2-cyano-(S)-pyrrolidine","C121834","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14985056","K579, a slow-binding inhibitor of dipeptidyl peptidase IV, is a long-acting hypoglycemic agent.","14985056",40]
["1-(((2-((5-iodopyridin-2-yl)amino)ethyl)amino)acetyl)-2-cyanopyrrolidine","1-(((2-((5-iodopyridin-2-yl)amino)ethyl)amino)acetyl)-2-cyanopyrrolidine","C482908","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12832764","High-resolution structure of human apo dipeptidyl peptidase IV/CD26 and its complex with 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)-acetyl]-2-cyano-(S)-pyrrolidine.","12832764",40]
["1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol","1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol","C435044","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15559765","In vivo molecular pharmacology and antitumor activity of the targeted Akt inhibitor PX-316.","15559765",40]
["1-((2-((2-chloropyridin-4yl)amino)-4'-(cyclopropylmethyl)-(4,5'-bipyrimidin)-2'-yl)amino)-2-methylpropan-2-ol","1-((2-((2-chloropyridin-4yl)amino)-4'-(cyclopropylmethyl)-(4,5'-bipyrimidin)-2'-yl)amino)-2-methylpropan-2-ol","C000593572","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25177796","Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase.","25177796",40]
["1-((2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)pyridin-3-yl)methyl)-3-(3-oxo-3,4-dihydro-2H-benzo(b)(1,4)oxazin-8-yl)urea","1-((2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)pyridin-3-yl)methyl)-3-(3-oxo-3,4-dihydro-2H-benzo(b)(1,4)oxazin-8-yl)urea","C000624293","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28892388","Novel Radiolabeled Vanilloid with Enhanced Specificity for Human Transient Receptor Potential Vanilloid 1 (TRPV1).","28892388",40]
["1-((2-(acetylamino)-2-carboxyethyl)thio)-2-amino-3-oxo-8-carboxyl-3H-phenoxiazine","1-((2-(acetylamino)-2-carboxyethyl)thio)-2-amino-3-oxo-8-carboxyl-3H-phenoxiazine","C485864","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16282322","A novel o-aminophenol oxidase responsible for formation of the phenoxazinone chromophore of grixazone.","16282322",40]
["1-((2-(acetylamino)-2-carboxyethyl)thio)-2-amino-3-oxo-8-formyl-3H-phenoxiazine","1-((2-(acetylamino)-2-carboxyethyl)thio)-2-amino-3-oxo-8-formyl-3H-phenoxiazine","C485863","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16282322","A novel o-aminophenol oxidase responsible for formation of the phenoxazinone chromophore of grixazone.","16282322",40]
["1-((2-(acetylamino)-2-carboxyethyl)thio)-2-amino-3-oxo-8-formyl-3H-phenoxiazine","1-((2-(acetylamino)-2-carboxyethyl)thio)-2-amino-3-oxo-8-formyl-3H-phenoxiazine","C485863","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17337580","A-factor and phosphate depletion signals are transmitted to the grixazone biosynthesis genes via the pathway-specific transcriptional activator GriR.","17337580",40]
["1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","C061818","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,1991,"1683214","Synergistic inhibition of human immunodeficiency virus type 1 (HIV-1) replication in vitro by 1-[(2-hydroxyethoxy)methyl]-6-phenylthiothymine (HEPT) and recombinant alpha interferon.","1683214",40]
["1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","C061818","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1989,"2575380","Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative.","2575380",40]
["1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","C061818","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"21947448","Docking, molecular dynamics and quantitative structure-activity relationship studies for HEPTs and DABOs as HIV-1 reverse transcriptase inhibitors.","21947448",40]
["1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","C061818","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8328988","Effect of human serum on the in vitro anti-HIV-1 activity of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) derivatives as related to their lipophilicity and serum protein binding.","8328988",40]
["1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","C061818","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9435895","A 3D QSAR study of a series of HEPT analogues: the influence of conformational mobility on HIV-1 reverse transcriptase inhibition.","9435895",40]
["1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine","C061818","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1996,"8691437","Synthesis and potent anti-HIV-1 activity of novel 6-benzyluracil analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.","8691437",40]
["1-((2'-methoxy-(1,1'-biphenyl)-3-yl)methyl)-4-(2-methoxyphenyl)piperazine","1-((2'-methoxy-(1,1'-biphenyl)-3-yl)methyl)-4-(2-methoxyphenyl)piperazine","C000594011","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"24039134","Aryl biphenyl-3-ylmethylpiperazines as 5-HT7 receptor antagonists.","24039134",40]
["1-((2-methylbenzimidazol-1-yl)methyl)-2-oxoindolin-3-ylidene)amino)thiourea","1-((2-methylbenzimidazol-1-yl)methyl)-2-oxoindolin-3-ylidene)amino)thiourea","C000613466","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26843462","Inhibition of Chikungunya Virus Replication by 1-[(2-Methylbenzimidazol-1-yl) Methyl]-2-Oxo-Indolin-3-ylidene] Amino] Thiourea(MBZM-N-IBT).","26843462",40]
["1-((3,4,5-trimethoxyphenyl)carbonyl)-1H-indazol-5-amine","1-((3,4,5-trimethoxyphenyl)carbonyl)-1H-indazol-5-amine","C540326","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19331414","Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin.","19331414",40]
["1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone","1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone","C053433","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21458438","DIF-1 regulates Dictyostelium basal disc differentiation by inducing the nuclear accumulation of a bZIP transcription factor.","21458438",40]
["1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone","1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone","C053433","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22699506","Identification of the kinase that activates a nonmetazoan STAT gives insights into the evolution of phosphotyrosine-SH2 domain signaling.","22699506",40]
["1-((4-((((3-isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl)amino)methyl)piperidin-1-yl)methyl)cyclobutanecarboxylic acid","1-((4-((((3-isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl)amino)methyl)piperidin-1-yl)methyl)cyclobutanecarboxylic acid","C545705","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19717010","Pharmacological characterization and determination of pharmacokinetic and pharmacodynamic relationship of PF-00885706, a novel partial agonist selective for the 5-HT(4) receptor.","19717010",40]
["1-((4-chlorophenyl)methyl)-3-benzyl-2,1,3-benzothiadiazin-4-one 2,2-dioxide","1-((4-chlorophenyl)methyl)-3-benzyl-2,1,3-benzothiadiazin-4-one 2,2-dioxide","C413348","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2000,"10966745","Nonnucleoside human cytomegalovirus inhibitors: synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives.","10966745",40]
["1-((4-chlorophenyl)sulfonyl)-2-(2-thienyl)pyrrolidine","1-((4-chlorophenyl)sulfonyl)-2-(2-thienyl)pyrrolidine","C545537","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19831392","Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker.","19831392",40]
["1-((4-methoxyanilino)methyl)-2-naphthol","1-((4-methoxyanilino)methyl)-2-naphthol","C000616612","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26062445","Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasion.","26062445",40]
["1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine","1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine","C484309","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,-1,2012,"22897580","Advantages of histamine H4 receptor antagonist usage with H1 receptor antagonist for the treatment of murine allergic contact dermatitis.","22897580",40]
["1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine","1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine","C484309","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2009,"18647342","Histamine H4 receptor antagonism reduces hapten-induced scratching behaviour but not inflammation.","18647342",40]
["1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine","1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine","C484309","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2016,"26892271","Inhibitory effect of a histamine 4 receptor antagonist on CCL17 and CCL22 production by monocyte-derived Langerhans cells in patients with atopic dermatitis.","26892271",40]
["1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine","1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine","C484309","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2009,"19652466","Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist.","19652466",40]
["1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine","1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine","C484309","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21134907","Agonist-biased signaling at the histamine H4 receptor: JNJ7777120 recruits β-arrestin without activating G proteins.","21134907",40]
["1-(1-(2,3-dihydrobenzo(1,4)dioxin-2-yl)methyl)-4-(3-methoxymethylpyridin-2-yl)piperazine","1-(1-(2,3-dihydrobenzo(1,4)dioxin-2-yl)methyl)-4-(3-methoxymethylpyridin-2-yl)piperazine","C000598340","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24838249","¹¹C-ORM-13070, a novel PET ligand for brain α₂C-adrenoceptors: radiometabolism, plasma pharmacokinetics, whole-body distribution and radiation dosimetry in healthy men.","24838249",40]
["1-(1-(2,3-dihydrobenzo(1,4)dioxin-2-yl)methyl)-4-(3-methoxymethylpyridin-2-yl)piperazine","1-(1-(2,3-dihydrobenzo(1,4)dioxin-2-yl)methyl)-4-(3-methoxymethylpyridin-2-yl)piperazine","C000598340","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25530024","Validation of [(11) C]ORM-13070 as a PET tracer for alpha2c -adrenoceptors in the human brain.","25530024",40]
["1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine","1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine","C056415","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10664474","1-[1-(2-Benzo[b]thiopheneyl)cyclohexyl]piperidine hydrochloride (BTCP) yields two active primary metabolites in vivo. Identification and quantification of BTCP primary metabolites in mice plasma, urine, and brain and their affinity for the neuronal dopamine transporter.","10664474",40]
["1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine","1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine","C056415","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7805759","Thermodynamics of the binding of BTCP (GK 13) and related derivatives on the dopamine neuronal carrier.","7805759",40]
["1-(1-(3-(methylsulfonyl)phenyl)-7-propoxyindolizin-3-yl)ethanone","1-(1-(3-(methylsulfonyl)phenyl)-7-propoxyindolizin-3-yl)ethanone","C000609271","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"25799074","Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.","25799074",40]
["1-(1-(4-methoxyphenyl)-3-phenylallylidene) thiosemicarbazide","1-(1-(4-methoxyphenyl)-3-phenylallylidene) thiosemicarbazide","C585820","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23461881","Microwave-assisted synthesis and tyrosinase inhibitory activity of chalcone derivatives.","23461881",40]
["1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)ethanone","1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)ethanone","C542745","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24246180","Fragrance material review on 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)ethanone (OTNE).","24246180",40]
["1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane","1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane","C572723","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22172391","68Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers.","22172391",40]
["1-(1,4-benzodioxan-6-ylcarbonyl)piperidine","1-(1,4-benzodioxan-6-ylcarbonyl)piperidine","C443080","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19717789","Modulation of agonist binding to AMPA receptors by 1-(1,4-benzodioxan-6-ylcarbonyl)piperidine (CX546): differential effects across brain regions and GluA1-4/transmembrane AMPA receptor regulatory protein combinations.","19717789",40]
["1-(1-butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine","1-(1-butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine","C120154","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23926946","ExoSensor 517: a dual-analyte fluorescent chemosensor for visualizing neurotransmitter exocytosis.","23926946",40]
["1-(1-glycero)dodeca-1,3,5,7,9-pentaene","1-(1-glycero)dodeca-1,3,5,7,9-pentaene","C037357","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2790820","Reactivity of fecapentaene-12 toward thiols, DNA, and these constituents in human fibroblasts.","2790820",40]
["1-(1H-benzo(d)imidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one","1-(1H-benzo(d)imidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one","C000620803","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28446518","Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer's Disease-Studies on Relation to Effective Target Occupancy.","28446518",40]
["1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine","1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine","C110851","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1998,"9498817","Inhibition of HIV-1 Nef-induced apoptosis of uninfected human blood cells by serine/threonine protein kinase inhibitors, fasudil hydrochloride and M3.","9498817",40]
["1-(1-naphthyl)piperazine","1-(1-naphthyl)piperazine","C048241","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15745826","1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands.","15745826",40]
["1-(1-naphthylmethyl)piperazine","1-(1-naphthylmethyl)piperazine","C511391","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28890187","Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance.","28890187",40]
["1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine","1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine","C044630","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12657288","Further exploration of 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]piperazine (GBR 12909): role of N-aromatic, N-heteroaromatic, and 3-oxygenated N-phenylpropyl substituents on affinity for the dopamine and serotonin transporter.","12657288",40]
["1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine","1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine","C044630","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2004,"15120584","Effect of 1,2,3,4,-tetrahydroisoquinoline administration under conditions of CYP2D inhibition on dopamine metabolism, level of tyrosine hydroxylase protein and the binding of [3H]GBR 12,935 to dopamine transporter in the rat nigrostriatal, dopaminergic system.","15120584",40]
["1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine","1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine","C044630","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8110814","The in situ size of the dopamine transporter is a tetramer as estimated by radiation inactivation.","8110814",40]
["1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine","1-(2 (diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine","C044630","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8263534","[3H]GBR-12935 binding to cytochrome P450 in the human brain.","8263534",40]
["1-(2-(18F)fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo-isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole","1-(2-(18F)fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo-isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole","C571781","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"21668889","Characterization of 1-(2-[18F] fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo- isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole, a PET ligand for imaging the metabotropic glutamate receptor type 1 in rat and monkey brains.","21668889",40]
["1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole","1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole","C063159","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2006,"16539844","Interaction between Cl- channels and CRAC-related Ca2+ signaling during T lymphocyte activation and proliferation.","16539844",40]
["1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole","1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole","C063159","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21470712","The anti-inflammatory effect of the SOCC blocker SK&amp;F 96365 on mouse lymphocytes after stimulation by Con A or PMA/ionomycin.","21470712",40]
["1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole","1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole","C063159","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"7858878","Inhibition by SK&amp;F 96365 of Ca2+ current, IL-2 production and activation in T lymphocytes.","7858878",40]
["1-(2-(4-(4-fluorobenzyl)-4-hydroxypiperidin-1-yl)ethyl)-3-(thieno(3,2-b)pyridin-7-yl)urea","1-(2-(4-(4-fluorobenzyl)-4-hydroxypiperidin-1-yl)ethyl)-3-(thieno(3,2-b)pyridin-7-yl)urea","C000600089","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25452001","Synthesis and SAR of thieno[3,2-b]pyridinyl urea derivatives as urotensin-II receptor antagonists.","25452001",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C323,B323)","v":"1-(2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl)-3-(2-methylquinolin-4-yl)urea"},"1-(2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl)-3-(2-methylquinolin-4-yl)urea","C493249","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J323,K323)","v":"Skin"},"D012867","Skin",0,1,2013,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q323,Q323)","v":"22886350"},"Effectiveness of palosuran in bleomycin-induced experimental scleroderma.","22886350",40]
["1-(2-(acridin-9-ylamino)ethyl)-1,3-dimethylthiourea","1-(2-(acridin-9-ylamino)ethyl)-1,3-dimethylthiourea","C471910","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15222767","Unique base-step recognition by a platinum-acridinylthiourea conjugate leads to a DNA damage profile complementary to that of the anticancer drug cisplatin.","15222767",40]
["1-(2-(benzo(d)(1,3)dioxol-6-yl)ethyl)-4-(2-methoxyphenyl)piperazine","1-(2-(benzo(d)(1,3)dioxol-6-yl)ethyl)-4-(2-methoxyphenyl)piperazine","C000598115","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21549456","Discovery of LASSBio-772, a 1,3-benzodioxole N-phenylpiperazine derivative with potent alpha 1A/D-adrenergic receptor blocking properties.","21549456",40]
["1-(2-(benzyloxy)ethyl)imidazole","1-(2-(benzyloxy)ethyl)imidazole","C510131","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16439365","Conformational flexibility of mammalian cytochrome P450 2B4 in binding imidazole inhibitors with different ring chemistry and side chains. Solution thermodynamics and molecular modeling.","16439365",40]
["1-(2-(bis(phenyl)methoxy)ethyl)-4-(3-(3'-azidophenyl)propyl)piperazine","1-(2-(bis(phenyl)methoxy)ethyl)-4-(3-(3'-azidophenyl)propyl)piperazine","C068380","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"2017146","Photoaffinity labeling of the dopamine reuptake carrier protein with 3-azido[3H]GBR-12935.","2017146",40]
["1-(2-(decylthio)ethyl)azacyclopentane-2-one","1-(2-(decylthio)ethyl)azacyclopentane-2-one","C075725","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2004,"15488678","Effects of HPE-101, a skin penetration enhancer, on human erythrocyte membranes.","15488678",40]
["1-(2-(diphenylmethoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine","1-(2-(diphenylmethoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine","C039737","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1996,"8773464","Complex ionic control of [3H]GBR 12783 binding to the dopamine neuronal carrier.","8773464",40]
["1-(2-(N-phenylbenzenesulfonamido)ethyl)-1H-1,2,3-triazole-4,5-dicarboxylic acid","1-(2-(N-phenylbenzenesulfonamido)ethyl)-1H-1,2,3-triazole-4,5-dicarboxylic acid","C581248","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23218602","Fragment-based discovery of novel and selective mPGES-1 inhibitors Part 1: identification of sulfonamido-1,2,3-triazole-4,5-dicarboxylic acid.","23218602",40]
["1-(2,1,3-benzothiadiazol-4-yl)-3-((E)-(4-hydroxyphenyl)methyleneamino)urea","1-(2,1,3-benzothiadiazol-4-yl)-3-((E)-(4-hydroxyphenyl)methyleneamino)urea","C000595197","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25174000","A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry.","25174000",40]
["1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one","1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one","C482649","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,2003,"12835896","1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one, a chalcone derivative with analgesic, anti-inflammatory and immunomodulatory properties.","12835896",40]
["1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole","1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole","C463040","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21737287","Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imaging.","21737287",40]
["1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole","1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole","C463040","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23795580","Radiolabeling and in vitro /in vivo evaluation of N-(1-adamantyl)-8-methoxy-4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxamide as a PET probe for imaging cannabinoid type 2 receptor.","23795580",40]
["1-(2,4,4,5,5-pentamethyl-1-cyclopenten-1-yl)ethan-1-one","1-(2,4,4,5,5-pentamethyl-1-cyclopenten-1-yl)ethan-1-one","C000589215","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24246176","Fragrance material review on 1-(2,4,4,5,5-pentamethyl-1-cyclopenten-1-yl)ethan-1-one.","24246176",40]
["1-(2,4-dichlorobenzyl)indazole-3-carbohydrazide","1-(2,4-dichlorobenzyl)indazole-3-carbohydrazide","C432482","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25620224","Interaction of oligomeric breast cancer resistant protein (BCRP) with adjudin: a male contraceptive with anti-cancer activity.","25620224",40]
["1-(2,4-dimethyl-3-cyclohexenyl)-2,2-dimethylpropan-1-one","1-(2,4-dimethyl-3-cyclohexenyl)-2,2-dimethylpropan-1-one","C000589214","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24246190","Fragrance material review on 1-(2,4-dimethyl-3-cyclohexenyl)-2,2-dimethylpropan-1-one.","24246190",40]
["1-(2,5,5-trimethylcycloheptyl)ethan-1-one","1-(2,5,5-trimethylcycloheptyl)ethan-1-one","C000589235","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23911797","Fragrance material review on 1-(2,5,5-trimethylcycloheptyl)ethan-1-one.","23911797",40]
["1-(2,5-dichlorophenyl)-3-(4-quinolinyl)-2-propen-1-one","1-(2,5-dichlorophenyl)-3-(4-quinolinyl)-2-propen-1-one","C097597","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"8544179","In vitro antimalarial activity of chalcones and their derivatives.","8544179",40]
["1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-butenone","1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-butenone","C057540","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1988,"3180787","TMCHB: a possible alternative to DNCB in skin testing for immune competence.","3180787",40]
["1-(2,6,6-trimethyl-2-cyclohexen-1-yl)pent-1-en-3-one","1-(2,6,6-trimethyl-2-cyclohexen-1-yl)pent-1-en-3-one","C000589237","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24246179","Fragrance material review on 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)pent-1-en-3-one.","24246179",40]
["1-(2,6-dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea","1-(2,6-dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea","C577496","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22906739","1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea: a novel cyclophilin A allosteric activator.","22906739",40]
["1-(2,6-diethylphenyl)imidazolidin-2-thione","1-(2,6-diethylphenyl)imidazolidin-2-thione","C514768","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"15841226","Octopaminergic agonists for the cockroach neuronal octopamine receptor.","15841226",40]
["1-(2,6-diethylphenyl)imidazolidine","1-(2,6-diethylphenyl)imidazolidine","C514769","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"15841226","Octopaminergic agonists for the cockroach neuronal octopamine receptor.","15841226",40]
["1-(2',6'-difluorophenyl)-1H,3H-thiazolo(3,4-a)benzimidazole","1-(2',6'-difluorophenyl)-1H,3H-thiazolo(3,4-a)benzimidazole","C073244","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,1991,"1686551","Anti-HIV agents II. Synthesis and in vitro anti-HIV activity of novel 1H,3H-thiazolo[3,4-a]benzimidazoles.","1686551",40]
["1-(2',6'-difluorophenyl)-1H,3H-thiazolo(3,4-a)benzimidazole","1-(2',6'-difluorophenyl)-1H,3H-thiazolo(3,4-a)benzimidazole","C073244","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8097690","Metabolism and disposition of a thiazolobenzimidazole active against human immunodeficiency virus-1.","8097690",40]
["1-(2-azido-6-chloropyrid-4-yl)-3-phenylurea","1-(2-azido-6-chloropyrid-4-yl)-3-phenylurea","C098201","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11516147","Photoaffinity labelling with the cytokinin agonist azido-CPPU of a 34 kDa peptide of the intracellular pathogenesis-related protein family in the moss Physcomitrella patens.","11516147",40]
["1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea","1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea","C549500","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19422399","SB265610 is an allosteric, inverse agonist at the human CXCR2 receptor.","19422399",40]
["1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea","1-(2-chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea","C052991","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8174203","5-Fluorouracil causes alterations in the pharmacokinetic profile of tauromustine in NMRI mice.","8174203",40]
["1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea","1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea","C018627","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7284999","Phase I trial and clinical pharmacology of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea.","7284999",40]
["1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole","1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole","C472829","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21818401","Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR.","21818401",40]
["1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole","1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole","C472829","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24896564","Structure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDO.","24896564",40]
["1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole","1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole","C472829","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2008,"18608528","Immunomodulatory activity of synthetic triterpenoids: inhibition of lymphocyte proliferation, cell-mediated cytotoxicity, and cytokine gene expression through suppression of NF-kappaB.","18608528",40]
["1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole","1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole","C472829","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2017,"29155145","Differential Effects of the Nrf2 Activators tBHQ and CDDO-Im on the Early Events of T Cell Activation.","29155145",40]
["1-(2-cyclopropylethyl)-3-(1,1-dioxo-2H-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-2(1H)-quinolinone","1-(2-cyclopropylethyl)-3-(1,1-dioxo-2H-1,2,4-benzothiadiazin-3-yl)-6-fluoro-4-hydroxy-2(1H)-quinolinone","C508992","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16451063","3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.","16451063",40]
["1-(2-fluoro-4-((5-methyl-5H-pyrrolo(3,2-d)pyrimidin-4-yl)oxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea","1-(2-fluoro-4-((5-methyl-5H-pyrrolo(3,2-d)pyrimidin-4-yl)oxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea","C555239","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20833055","Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation.","20833055",40]
["1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one","1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one","C000594749","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25815469","Characterization of binding and inhibitory properties of TAK-063, a novel phosphodiesterase 10A inhibitor.","25815469",40]
["1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one","1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one","C000594749","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27423256","A human [(11)C]T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor.","27423256",40]
["1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide","1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide","C530596","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18837519","Chemical reactivity of methoxy 4-o-aryl quinolines: identification of glutathione displacement products in vitro and in vivo.","18837519",40]
["1-(2-hydroxy-3- methyl 4,5-dimethoxyphenyl)-3-(1H-pyrrol-2-yl)-2-propen-1-one","1-(2-hydroxy-3- methyl 4,5-dimethoxyphenyl)-3-(1H-pyrrol-2-yl)-2-propen-1-one","C000608030","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27525951","Target fishing of glycopentalone using integrated inverse docking and reverse pharmacophore mapping approach.","27525951",40]
["1-(2-hydroxy-5-methylphenyl)-3,5-dioxo-1H-imidazo(3,4-b)isoindole","1-(2-hydroxy-5-methylphenyl)-3,5-dioxo-1H-imidazo(3,4-b)isoindole","C000605264","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25068392","Exploring the interaction of a micelle entrapped biologically important proton transfer probe with the model transport protein bovine serum albumin.","25068392",40]
["1-(2-methoxy-4,6-bis(methoxymethoxy)phenyl)-3-(3-nitrophenyl)prop-2-en-1-one","1-(2-methoxy-4,6-bis(methoxymethoxy)phenyl)-3-(3-nitrophenyl)prop-2-en-1-one","C538718","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2014,"24067925","Antidepressant-like and anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa).","24067925",40]
["1-(2-methoxy-phenyl)-4-(4-(4-(6-imidazol(2,1-b) thiazolyl)-phenoxy)-butyl-4-(14)C)-piperazine dimethane","1-(2-methoxy-phenyl)-4-(4-(4-(6-imidazol(2,1-b) thiazolyl)-phenoxy)-butyl-4-(14)C)-piperazine dimethane","C427703","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2005,"16144658","Lack of effect of reserpine-induced dopamine depletion on the binding of the dopamine-D3 selective radioligand, [11C]RGH-1756.","16144658",40]
["1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea","1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea","C420062","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2003,"14622212","Hypocretin-1 causes G protein activation and increases ACh release in rat pons.","14622212",40]
["1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea","1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea","C420062","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14691055","Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor.","14691055",40]
["1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea","1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea","C420062","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21478014","Diaryl urea analogues of SB-334867 as orexin-1 receptor antagonists.","21478014",40]
["1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea","1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea","C420062","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22079339","Mapping of the binding sites for the OX1 orexin receptor antagonist, SB-334867, using orexin/hypocretin receptor chimaeras.","22079339",40]
["1-(2-nitrophenyl)diazoethane","1-(2-nitrophenyl)diazoethane","C488730","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15240139","Recovery of the oxidative activity of caged bovine haemoglobin after UV photolysis.","15240139",40]
["1-(2-nitrophenyl)ethanol","1-(2-nitrophenyl)ethanol","C063593","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7672186","The modulation of protein A-IgG(Fc) binding by the reversible addition of 2-nitrobenzyl groups.","7672186",40]
["1-(2-oxo-2-phenylacetyl)-N-(3-phenylpropyl)piperidine-2-carboxamide","1-(2-oxo-2-phenylacetyl)-N-(3-phenylpropyl)piperidine-2-carboxamide","C579814","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23301792","The precise chemical-physical nature of the pharmacore in FK506 binding protein inhibition: ElteX, a New class of nanomolar FKBP12 ligands.","23301792",40]
["1-(2-pyridinyl)piperazine","1-(2-pyridinyl)piperazine","C052140","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17494642","6-Hydroxybuspirone is a major active metabolite of buspirone: assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in rats.","17494642",40]
["1-(2-pyrimidinyl)piperazine","1-(2-pyrimidinyl)piperazine","C037921","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"2866634","Disposition of the psychotropic drugs buspirone, MJ-13805 and piribedil, and of their common active metabolite 1-(2-pyrimidinyl)-piperazine in the rat.","2866634",40]
["1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-bromophenyl)-3-isopropoxy-1H-pyrrol-2(5H)-one","1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-bromophenyl)-3-isopropoxy-1H-pyrrol-2(5H)-one","C577939","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"23046248","Discovery, synthesis, and biological evaluation of orally active pyrrolidone derivatives as novel inhibitors of p53-MDM2 protein-protein interaction.","23046248",40]
["1-(3-(2-pyrrolidinylethoxy)phenyl)-3-((3-(trifluoromethyl)phenyl)azamethylene)benzo(d)azolin-2-one","1-(3-(2-pyrrolidinylethoxy)phenyl)-3-((3-(trifluoromethyl)phenyl)azamethylene)benzo(d)azolin-2-one","C510289","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23461969","Theoretical characterization of galanin receptor type 3 (Gal3 ) and its interaction with agonist (GALANIN) and antagonists (SNAP 37889 and SNAP 398299): an in silico analysis.","23461969",40]
["1-(3-(3-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)phenyl)guanidine","1-(3-(3-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)phenyl)guanidine","C000594995","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25025991","New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.","25025991",40]
["1-(3-(4-butyl-1-piperidinyl)propyl)-3,4-dihydro-2(1H)-quinolinone","1-(3-(4-butyl-1-piperidinyl)propyl)-3,4-dihydro-2(1H)-quinolinone","C531940","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19767446","Contrasting effects of allosteric and orthosteric agonists on m1 muscarinic acetylcholine receptor internalization and down-regulation.","19767446",40]
["1-(3,3-dimethylbicyclo(2.2.1)hept-2-yl)ethane-1-one","1-(3,3-dimethylbicyclo(2.2.1)hept-2-yl)ethane-1-one","C000589217","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24246178","Fragrance material review on 1-(3,3-dimethylbicyclo[2.2.1]hept-2-yl)ethane-1-one.","24246178",40]
["1-(3,3-dimethylcyclohexyl)ethan-1-one","1-(3,3-dimethylcyclohexyl)ethan-1-one","C000589155","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24246184","Fragrance material review on 1-(3,3-dimethylcyclohexyl)ethan-1-one.","24246184",40]
["1-(3,3-dimethylcyclohexyl)pent-4-en-1-one","1-(3,3-dimethylcyclohexyl)pent-4-en-1-one","C000589212","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24246188","Fragrance material review on 1-(3,3-dimethylcyclohexyl)pent-4-en-1-one.","24246188",40]
["1-(3,4,5-trimethoxyphenyl)-5-(4-ethoxyphenyl)-1H-1,2,4-triazole","1-(3,4,5-trimethoxyphenyl)-5-(4-ethoxyphenyl)-1H-1,2,4-triazole","C550171","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20420439","Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.","20420439",40]
["1-(3,4-dichlorophenyl)-3-(4-((1-ethyl-3-piperidyl)amino)-6-methyl-2-pyrimidinyl)guanidine","1-(3,4-dichlorophenyl)-3-(4-((1-ethyl-3-piperidyl)amino)-6-methyl-2-pyrimidinyl)guanidine","C007349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"26517684","Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma.","26517684",40]
["1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-morpholino-1H-pyrrole-2,5-dione","1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-morpholino-1H-pyrrole-2,5-dione","C579728","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23231413","An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity.","23231413",40]
["1-(3,4-dichlorophenyl)-3-azabicyclo-(3.1.0)hexane hydrochloride","1-(3,4-dichlorophenyl)-3-azabicyclo-(3.1.0)hexane hydrochloride","C474071","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23826879","Biopharmaceutical characterization, metabolism, and brain penetration of the triple reuptake inhibitor amitifadine.","23826879",40]
["1-(3,4-dichlorophenyl)-3-azabicyclo-(3.1.0)hexane hydrochloride","1-(3,4-dichlorophenyl)-3-azabicyclo-(3.1.0)hexane hydrochloride","C474071","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2018,"29451287","Computational identification of the binding mechanism of a triple reuptake inhibitor amitifadine for the treatment of major depressive disorder.","29451287",40]
["1-(3,4-dihydro-4-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)ethanone","1-(3,4-dihydro-4-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)ethanone","C000613480","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"26983826","Identification of cytoprotective constituents of the flower buds of Tussilago farfara against glucose oxidase-induced oxidative stress in mouse fibroblast NIH3T3 cells and human keratinocyte HaCaT cells.","26983826",40]
["1-(3',4'-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline","1-(3',4'-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline","C110419","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24832624","Endogenous neurotoxic dopamine derivative covalently binds to Parkinson's disease-associated ubiquitin C-terminal hydrolase L1 and alters its structure and function.","24832624",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C387,B387)","v":"1-(3,4-dimethoxybenzyl)-5-(2-(methylsulfonyl)-6-(trifluoromethyl)pyrimidin-4-yl)pyridin-2(1H)-one"},"1-(3,4-dimethoxybenzyl)-5-(2-(methylsulfonyl)-6-(trifluoromethyl)pyrimidin-4-yl)pyridin-2(1H)-one","C000622061","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J387,K387)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2016,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q387,Q387)","v":"27447985"},"A Small Molecule That Protects the Integrity of the Electron Transfer Chain Blocks the Mitochondrial Apoptotic Pathway.","27447985",40]
["1-(3,4-dimethoxyphenyl)-3-(9H-pyrido(3,4-b)indol-1-yl)prop-2-en-1-one","1-(3,4-dimethoxyphenyl)-3-(9H-pyrido(3,4-b)indol-1-yl)prop-2-en-1-one","C000622459","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27543608","Dual targeting of MDM2 with a novel small-molecule inhibitor overcomes TRAIL resistance in cancer.","27543608",40]
["1-(3,5,6-trimethyl-3-cyclohexen-1-yl)ethan-1-one","1-(3,5,6-trimethyl-3-cyclohexen-1-yl)ethan-1-one","C000589216","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24246177","Fragrance material review on 1-(3,5,6-trimethyl-3-cyclohexen-1-yl)ethan-1-one.","24246177",40]
["1-(3,5-bis-trifluoromethylphenyl)-3-(2,4-dibromo-6-(1H-tetrazol-5-yl)phenyl)urea","1-(3,5-bis-trifluoromethylphenyl)-3-(2,4-dibromo-6-(1H-tetrazol-5-yl)phenyl)urea","C541204","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25228688","Modulation of the voltage-gated potassium channel (Kv4.3) and the auxiliary protein (KChIP3) interactions by the current activator NS5806.","25228688",40]
["1-(3-biphenyl-4-ylbutyl)piperidine","1-(3-biphenyl-4-ylbutyl)piperidine","C584299","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23832823","Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds: promising neuroprotective agents acting as σ₁ receptor agonists.","23832823",40]
["1-(3-cyclohexen-1-ylcarbonyl)-2-methylpiperidine","1-(3-cyclohexen-1-ylcarbonyl)-2-methylpiperidine","C075892","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10403344","Short report: prevention of Schistosoma mansoni infections in mice by the insect repellents AI3-37220 and N,N-diethyl-3-methylbenzamide.","10403344",40]
["1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carbonitrile","1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carbonitrile","C569214","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21729242","Neutralization of haemorrhagic activity of viper venoms by 1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carbonitrile.","21729242",40]
["1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carbonitrile","1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carbonitrile","C569214","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21729242","Neutralization of haemorrhagic activity of viper venoms by 1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carbonitrile.","21729242",40]
["1-(3-dimethylaminopropyl)-3-ethylurea","1-(3-dimethylaminopropyl)-3-ethylurea","C477080","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2003,"12870119","Protection against lethal intra-abdominal sepsis by 1-(3-dimethylaminopropyl)-3-ethylurea.","12870119",40]
["1-(3-dimethylaminopropyl)-dimethylaminopropyl-ethylcarbodiimide hydrochloride","1-(3-dimethylaminopropyl)-dimethylaminopropyl-ethylcarbodiimide hydrochloride","C569779","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26671168","Folic-Acid-Modified Conducting Polymer: Electrochemical Detection of the Cell Attachment.","26671168",40]
["1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one","1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one","C569670","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22696419","Preclinical assessment of the absorption and disposition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor GDC-0980 and prediction of its pharmacokinetics and efficacy in human.","22696419",40]
["1-(4-((4-(dimethylamino)piperidin-1-yl)carbonyl)phenyl)-3-(4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl)urea","1-(4-((4-(dimethylamino)piperidin-1-yl)carbonyl)phenyl)-3-(4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl)urea","C549060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20166697","Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor.","20166697",40]
["1-(4-((4-(dimethylamino)piperidin-1-yl)carbonyl)phenyl)-3-(4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl)urea","1-(4-((4-(dimethylamino)piperidin-1-yl)carbonyl)phenyl)-3-(4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl)urea","C549060","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2017,"28543637","Evidence of the immunomodulatory role of dual PI3K/mTOR inhibitors in transplantation: an experimental study in mice.","28543637",40]
["1-(4-((4-phenyl-5-trifluoromethyl-2-thienyl)methoxy)benzyl)azetidine-3-carboxylic acid","1-(4-((4-phenyl-5-trifluoromethyl-2-thienyl)methoxy)benzyl)azetidine-3-carboxylic acid","C514353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16698892","Species differences in metabolism and pharmacokinetics of a sphingosine-1-phosphate receptor agonist in rats and dogs: formation of a unique glutathione adduct in the rat.","16698892",40]
["1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid","1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid","C578989","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2017,"28934113","Sphingosine 1-Phosphate Signaling and Its Pharmacological Modulation in Allogeneic Hematopoietic Stem Cell Transplantation.","28934113",40]
["1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid","1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid","C578989","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2016,"27566665","Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis.","27566665",40]
["1-(4-(1,2,3,4-tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone oxime","1-(4-(1,2,3,4-tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone oxime","C555223","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2016,"27663991","Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931.","27663991",40]
["1-(4-(2-chloroethyl)phenyl)-2-chloroethanol","1-(4-(2-chloroethyl)phenyl)-2-chloroethanol","C108055","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1997,"9255489","Pseudo flautist's lip: allergic contact cheilitis from geraniol.","9255489",40]
["1-(4-(2-methoxyisopropyl)phenyl)-3-(2-(4-methylpiperazin-1-yl)benzyl)pyrrolidin-2-one","1-(4-(2-methoxyisopropyl)phenyl)-3-(2-(4-methylpiperazin-1-yl)benzyl)pyrrolidin-2-one","C546827","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21538549","Characterization of in vivo pharmacological properties and sensitivity to endogenous serotonin of [11C] P943: a positron emission tomography study in Papio anubis.","21538549",40]
["1-(4-(2-methoxyisopropyl)phenyl)-3-(2-(4-methylpiperazin-1-yl)benzyl)pyrrolidin-2-one","1-(4-(2-methoxyisopropyl)phenyl)-3-(2-(4-methylpiperazin-1-yl)benzyl)pyrrolidin-2-one","C546827","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25427881","Test-retest reliability of the novel 5-HT1B receptor PET radioligand [11C]P943.","25427881",40]
["1-(4-(3-(4-(1H-benzo(d)imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)-2-fluoropropan-1-one","1-(4-(3-(4-(1H-benzo(d)imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)-2-fluoropropan-1-one","C000596178","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25502803","AMG 580: a novel small molecule phosphodiesterase 10A (PDE10A) positron emission tomography tracer.","25502803",40]
["1-(4-(3-(4-fluorophenyl)-1H-pyrrolo(3,2-b)pyridin-2-yl)pyridin-2-ylamino)propan-2-ol","1-(4-(3-(4-fluorophenyl)-1H-pyrrolo(3,2-b)pyridin-2-yl)pyridin-2-ylamino)propan-2-ol","C478623","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14561090","Design and synthesis of 4-azaindoles as inhibitors of p38 MAP kinase.","14561090",40]
["1-(4-(3-bromophenoxy)butyl)-1H-imidazole","1-(4-(3-bromophenoxy)butyl)-1H-imidazole","C579327","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22882835","Evaluation of imidazole-based compounds as heme oxygenase-1 inhibitors.","22882835",40]
["1-(4-(3-fluoro-4-(3-methyl-1,1-dioxo-6-phenyl(1,2)thiazinan-2-ylmethyl)phenyl)piperazin-1-yl)ethanone","1-(4-(3-fluoro-4-(3-methyl-1,1-dioxo-6-phenyl(1,2)thiazinan-2-ylmethyl)phenyl)piperazin-1-yl)ethanone","C000601735","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26061388","Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonist.","26061388",40]
["1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-3-methyl-5,5-diphenylimidazolidine-2,4-dione hydrochloride","1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-3-methyl-5,5-diphenylimidazolidine-2,4-dione hydrochloride","C573386","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22381672","Antiarrhythmic properties of phenylpiperazine derivatives of phenytoin with α₁-adrenoceptor affinities.","22381672",40]
["1-(4-(4-(3-oxa-8-azabicyclo(3.2.1)octan-8-yl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-(pyridin-4-yl)urea","1-(4-(4-(3-oxa-8-azabicyclo(3.2.1)octan-8-yl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-(pyridin-4-yl)urea","C549124","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26500112","A structural insight into the inhibitory mechanism of an orally active PI3K/mTOR dual inhibitor, PKI-179 using computational approaches.","26500112",40]
["1-(4-(4-fluorophenyl)piperazine-1-yl)-3-(2-oxopyrrolidin-1-yl)propane","1-(4-(4-fluorophenyl)piperazine-1-yl)-3-(2-oxopyrrolidin-1-yl)propane","C439505","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18412019","Absorption, protein binding, pharmacokinetics and excretion of the anti-ischemic and anti-hypertensive arylpiperazine derivative CDRI-93/478 in rats.","18412019",40]
["1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone","1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone","C517943","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2011,"21722102","Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1.","21722102",40]
["1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone","1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone","C517943","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28258163","G-1 Inhibits Breast Cancer Cell Growth via Targeting Colchicine-Binding Site of Tubulin to Interfere with Microtubule Assembly.","28258163",40]
["1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone","1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone","C517943","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21722102","Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1.","21722102",40]
["1-(4-(methylsulfonyl)phenyl)-3-(1H-pyrrolo(2,3-b)pyridin-5-yl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine","1-(4-(methylsulfonyl)phenyl)-3-(1H-pyrrolo(2,3-b)pyridin-5-yl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine","C000621046","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28131712","Discovery of pyrazolopyrimidine derivatives as novel inhibitors of ataxia telangiectasia and rad3 related protein (ATR).","28131712",40]
["1-(4-amino-3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one","1-(4-amino-3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one","C528604","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18083036","Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino-3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent.","18083036",40]
["1-(4-aminosulfonylphenylazo)-2-naphthol-6,8-disulfonate","1-(4-aminosulfonylphenylazo)-2-naphthol-6,8-disulfonate","C000610400","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26112153","Thermodynamics of binding of a sulfonamide inhibitor to metal-mutated carbonic anhydrase as studied by affinity capillary electrophoresis.","26112153",40]
["1-(4-bromoacetamidobenzyl)EDTA","1-(4-bromoacetamidobenzyl)EDTA","C042007","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10208819","Directed cleavage of RNA with protein-tethered EDTA-Fe.","10208819",40]
["1-(4-bromoacetamidobenzyl)EDTA","1-(4-bromoacetamidobenzyl)EDTA","C042007","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10890006","Directed hydroxyl radical probing of RNA from iron(II) tethered to proteins in ribonucleoprotein complexes.","10890006",40]
["1-(4-bromoacetamidobenzyl)EDTA","1-(4-bromoacetamidobenzyl)EDTA","C042007","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10973050","Protein-protein interactions mapped by artificial proteases: where sigma factors bind to RNA polymerase.","10973050",40]
["1-(4-bromoacetamidobenzyl)EDTA","1-(4-bromoacetamidobenzyl)EDTA","C042007","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12750380","Mapping sigma 54-RNA polymerase interactions at the -24 consensus promoter element.","12750380",40]
["1-(4-bromoacetamidobenzyl)EDTA","1-(4-bromoacetamidobenzyl)EDTA","C042007","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14712693","Principles and methods of affinity cleavage in studying transcription.","14712693",40]
["1-(4-bromoacetamidobenzyl)EDTA","1-(4-bromoacetamidobenzyl)EDTA","C042007","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17433366","Alanine scanning and Fe-BABE probing of the bacteriophage ø29 prohead RNA-connector interaction.","17433366",40]
["1-(4-bromoacetamidobenzyl)EDTA","1-(4-bromoacetamidobenzyl)EDTA","C042007","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7547857","Proximity mapping the surface of a membrane protein using an artificial protease: demonstration that the quinone-binding domain of subunit I is near the N-terminal region of subunit II of cytochrome bd.","7547857",40]
["1-(4-bromophenyl)-5-phenyl-1H-1,2,3-triazole","1-(4-bromophenyl)-5-phenyl-1H-1,2,3-triazole","C000616094","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27693762","The characterization of 1-(4-bromophenyl)-5-phenyl-1H-1,2,3-triazole on acute toxicity, antimicrobial activities, photophysical property, and binding to two globular proteins.","27693762",40]
["1-(4-chlorophenyl)-3-(3-(4-chlorophenyl)-5,5-dimethyl-1-(3-(5-nitrofuran-2-yl)allyldienehydrazinocarbonylmethyl)-2-oxoimidazolidin-4-yl)-1-hydroxyurea","1-(4-chlorophenyl)-3-(3-(4-chlorophenyl)-5,5-dimethyl-1-(3-(5-nitrofuran-2-yl)allyldienehydrazinocarbonylmethyl)-2-oxoimidazolidin-4-yl)-1-hydroxyurea","C492847","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"21124757","The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group.","21124757",40]
["1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea","1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea","C526691","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21189269","Effects of the allosteric antagonist 1-(4-chlorophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea (PSNCBAM-1) on CB1 receptor modulation in the cerebellum.","21189269",40]
["1-(4-chlorophenyl)-4,4-dimethyl-5-diethylamino-1-penten-3-one","1-(4-chlorophenyl)-4,4-dimethyl-5-diethylamino-1-penten-3-one","C059871","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2729541","1-p-chlorophenyl-4,4-dimethyl-5-diethylamino-1-penten-3-one hydrobromide, a sulfhydryl-specific compound which reacts irreversibly with protein thiols but reversibly with small molecular weight thiols.","2729541",40]
["1-(4-chlorophenyl)-benzo-2,5-quinone","1-(4-chlorophenyl)-benzo-2,5-quinone","C000597136","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23770201","Selenoprotein P regulates 1-(4-Chlorophenyl)-benzo-2,5-quinone-induced oxidative stress and toxicity in human keratinocytes.","23770201",40]
["1-(4-chlorophenyl)-benzo-2,5-quinone","1-(4-chlorophenyl)-benzo-2,5-quinone","C000597136","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"25417049","Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes.","25417049",40]
["1-(4-chlorophenyl)-benzo-2,5-quinone","1-(4-chlorophenyl)-benzo-2,5-quinone","C000597136","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2015,"25668756","Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes.","25668756",40]
["1-(4-chlorophenyl)-benzo-2,5-quinone","1-(4-chlorophenyl)-benzo-2,5-quinone","C000597136","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2015,"26004620","Down-regulation of peroxisome proliferator activated receptor γ coactivator 1α induces oxidative stress and toxicity of 1-(4-Chlorophenyl)-benzo-2,5-quinone in HaCaT human keratinocytes.","26004620",40]
["1-(4-chlorophenyl)imidazole","1-(4-chlorophenyl)imidazole","C525744","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25043499","Including ligand-induced protein flexibility into protein tunnel prediction.","25043499",40]
["1-(4-di-hydroxy-3,5-dioxa-4-borabicyclo(4.4.0)deca-7,9,11-trien-9-yl)-2-(tert-butylamino)ethanol","1-(4-di-hydroxy-3,5-dioxa-4-borabicyclo(4.4.0)deca-7,9,11-trien-9-yl)-2-(tert-butylamino)ethanol","C542224","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"19874116","Pharmacokinetic parameters and a theoretical study about metabolism of BR-AEA (a salbutamol derivative) in rabbit.","19874116",40]
["1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane","1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane","C091518","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14637376","[3H]Ethynylbicycloorthobenzoate ([3H]EBOB) binding in recombinant GABAA receptors.","14637376",40]
["1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane","1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane","C091518","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2005,"15913670","High affinity, heterogeneous displacement of [3H]EBOB binding to cerebellar GABA A receptors by neurosteroids and GABA agonists.","15913670",40]
["1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane","1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane","C091518","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8968340","Characterization of [3H]ethynylbicycloorthobenzoate ([3H]EBOB) binding and the action of insecticides on the gamma-aminobutyric acid-gated chloride channel in cultured cerebellar granule neurons.","8968340",40]
["1-(4-fluoro-2-(2-nitrovinyl)phenyl)pyrrolidine","1-(4-fluoro-2-(2-nitrovinyl)phenyl)pyrrolidine","C000601182","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"26744907","1-[4-Fluoro-2-(2-nitrovinyl)phenyl]pyrrolidine Suppresses Toll-Like Receptor 4 Dimerization Induced by Lipopolysaccharide.","26744907",40]
["1-(4-fluorobenzoyl)-3-(((6-methoxy-2-naphthyl)oxy)methyl)azetidine-3-carboxylic acid","1-(4-fluorobenzoyl)-3-(((6-methoxy-2-naphthyl)oxy)methyl)azetidine-3-carboxylic acid","C570688","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21595651","In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP₂ receptor antagonist.","21595651",40]
["1-(4-fluorobenzyl)-4-((5,6-dimethoxy-1-oxoindan-2-fluoro-2-yl)methyl)piperidine","1-(4-fluorobenzyl)-4-((5,6-dimethoxy-1-oxoindan-2-fluoro-2-yl)methyl)piperidine","C510969","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16459263","Is subnanomolar binding affinity required for the in vivo imaging of acetylcholinesterase? Studies on 18F-labeled G379.","16459263",40]
["1-(4-hydroxy-3-(hydroxymethyl)-1-butyl)-5-(1-azido-2-chloroethyl)uracil","1-(4-hydroxy-3-(hydroxymethyl)-1-butyl)-5-(1-azido-2-chloroethyl)uracil","C440620","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2001,"11708924","Synthesis and antiviral activity of novel acyclic nucleoside analogues of 5-(1-azido-2-haloethyl)uracils.","11708924",40]
["1-(4-isothiocyanatobenzyl)diethylenetriaminepentaacetic acid","1-(4-isothiocyanatobenzyl)diethylenetriaminepentaacetic acid","C054343","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2095205","Radiometal labeling of immunoproteins: covalent linkage of 2-(4-isothiocyanatobenzyl)diethylenetriaminepentaacetic acid ligands to immunoglobulin.","2095205",40]
["1-(4-methoxybenzyl)-2-(4-methoxyphenyl)-1H-benzo(d)imidazole","1-(4-methoxybenzyl)-2-(4-methoxyphenyl)-1H-benzo(d)imidazole","C578318","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22854224","Antioxidant benzimidazole bind bovine serum albumin.","22854224",40]
["1-(4-phenyldiazenylphenyl)pyrrole-2,5-dione","1-(4-phenyldiazenylphenyl)pyrrole-2,5-dione","C546415","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19605460","Photocontrol of calmodulin interaction with target peptides using azobenzene derivative.","19605460",40]
["1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine","1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine","C552956","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21828261","Characterization of a novel potassium-competitive acid blocker of the gastric H,K-ATPase, 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine monofumarate (TAK-438).","21828261",40]
["1-(5,5-dimethylcyclohexen-1-yl)pent-4-en-1-one","1-(5,5-dimethylcyclohexen-1-yl)pent-4-en-1-one","C000589157","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24246187","Fragrance material review on 1-(5,5-dimethylcyclohexen-1-yl)pent-4-en-1-one.","24246187",40]
["1-(5-chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide","1-(5-chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide","C456029","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16210325","Mechanisms of cell-surface rerouting of an endoplasmic reticulum-retained mutant of the vasopressin V1b/V3 receptor by a pharmacological chaperone.","16210325",40]
["1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea","1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea","C508388","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19411608","An allosteric modulator of alpha7 nicotinic receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), causes conformational changes in the extracellular ligand binding domain similar to those caused by acetylcholine.","19411608",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C451,B451)","v":"1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea"},"1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea","C508388","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J451,K451)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2015,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q451,Q451)","v":"26211363"},"An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors.","26211363",40]
["1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid","1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid","C559853","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21372172","Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor.","21372172",40]
["1-(5-chloroindol-3-yl)-3-hydroxy-3-(2H-tetrazol-5-yl)propenone","1-(5-chloroindol-3-yl)-3-hydroxy-3-(2H-tetrazol-5-yl)propenone","C400757","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11543671","Ordered water and ligand mobility in the HIV-1 integrase-5CITEP complex: a molecular dynamics study.","11543671",40]
["1-(5-chloroindol-3-yl)-3-hydroxy-3-(2H-tetrazol-5-yl)propenone","1-(5-chloroindol-3-yl)-3-hydroxy-3-(2H-tetrazol-5-yl)propenone","C400757","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12609852","Molecular dynamics studies of the wild-type and double mutant HIV-1 integrase complexed with the 5CITEP inhibitor: mechanism for inhibition and drug resistance.","12609852",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2011,"21501850","Preventive and therapeutic effects of the selective Rho-kinase inhibitor fasudil on experimental autoimmune neuritis.","21501850",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2014,"24749492","Intranasal delivery of FSD-C10, a novel Rho kinase inhibitor, exhibits therapeutic potential in experimental autoimmune encephalomyelitis.","24749492",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1999,"10641489","Radiation augments a sequential program of differentiation in PKC inhibitor- pretreated mouse epidermal cells.","10641489",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2002,"12111351","Ca(2+)/calmodulin-dependent protein kinase (CaM-kinase) inhibitor KN-62 suppresses the activity of mitogen-activated protein kinase (MAPK), c-myc activation and human keratinocyte proliferation.","12111351",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1996,"8858879","Cytoplasmic desmosome formation by H-7 and EGF treatment in cultured fetal rat keratinocytes.","8858879",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11817672","Investigation of the inhibitory effects of HA-1077 and Y-32885 on the translocation of PKCbetaI, PKCbetaII and PKCzeta in human neutrophils.","11817672",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14656443","Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity.","14656443",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15797868","Neuroprotective effects of preconditioning ischemia on ischemic brain injury through down-regulating activation of JNK1/2 via N-methyl-D-aspartate receptor-mediated Akt1 activation.","15797868",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1658551","Properties and use of H-series compounds as protein kinase inhibitors.","1658551",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2169823","Search for the functional substrate proteins of protein kinases and their selective inhibitors.","2169823",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3390230","Putative binding site(s) of 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7) on protein kinase C.","3390230",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1996,"8660281","The role of protein kinase C in carbachol-induced and of cAMP-dependent protein kinase in isoproterenol-induced secretion in primary cultured guinea pig parotid acinar cells.","8660281",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9454739","Calcium/calmodulin-dependent protein kinase II controls alpha5beta1 integrin-mediated inside-out signaling.","9454739",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"22030503","Wound contraction is attenuated by fasudil inhibition of Rho-associated kinase.","22030503",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8858879","Cytoplasmic desmosome formation by H-7 and EGF treatment in cultured fetal rat keratinocytes.","8858879",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1991,"1650519","Modulation of cellular processes by H7, a non-selective inhibitor of protein kinases.","1650519",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1991,"2060574","Dissection of signals controlling T cell function and activation: H7, an inhibitor of protein kinase C, blocks induction of primary T cell proliferation by suppressing interleukin (IL)2 receptor expression without affecting IL2 production.","2060574",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23418431","Targeting the shift from M1 to M2 macrophages in experimental autoimmune encephalomyelitis mice treated with fasudil.","23418431",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1990,"2357216","Protein kinase inhibitor H-7 blocks accumulation of unspliced mRNA of human T-cell leukemia virus type I (HTLV-I).","2357216",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1990,"2383893","Regulation of mitogen-stimulated human T-cell proliferation, interleukin-2 production, and interleukin-2 receptor expression by protein kinase C inhibitor, H-7.","2383893",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1987,"2439080","The protein kinase C inhibitor H-7, inhibits antigen and IL-2-induced proliferation of murine T cell lines.","2439080",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"25287052","Fasudil mediates cell therapy of EAE by immunomodulating encephalomyelitic T cells and macrophages.","25287052",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2546543","Effects of H-7 are not exclusively mediated through protein kinase C or the cyclic nucleotide-dependent kinases.","2546543",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1989,"2606326","The protein kinase C inhibitor H-7 inhibits concanavalin A induced T-lymphocyte activation.","2606326",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1987,"2821109","Inhibition of antibodies to CD3 surface antigen and phytohemagglutinin-mediated T cellular responses by inhibiting Ca2+/phospholipid-dependent protein kinase activity with the aid of 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine dihydrochloride.","2821109",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1988,"3264806","Phorbol myristate acetate induces IL-2 secretion by HUT 78 cells by a mechanism independent of protein kinase C translocation.","3264806",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1997,"9247701","Preincubation of thymocytes with 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride (H-7) induces apoptosis in non-stimulated thymocytes.","9247701",40]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1998,"9498817","Inhibition of HIV-1 Nef-induced apoptosis of uninfected human blood cells by serine/threonine protein kinase inhibitors, fasudil hydrochloride and M3.","9498817",40]
["1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione","1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione","C060229","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11682455","Inhibition of acetylcholine-activated K(+) currents by U73122 is mediated by the inhibition of PIP(2)-channel interaction.","11682455",40]
["1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione","1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione","C060229","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17403917","The phosphoinositide-specific phospholipase C inhibitor U73122 (1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione) spontaneously forms conjugates with common components of cell culture medium.","17403917",40]
["1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione","1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione","C060229","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"22137889","Inhibition of 5-lipoxygenase by U73122 is due to covalent binding to cysteine 416.","22137889",40]
["1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione","1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione","C060229","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"7554485","Effects of an aminosteroid inhibitor of phospholipase C-dependent processes on the TCR-mediated signal transduction pathway in human T cells.","7554485",40]
["1-(6-methoxy-2H-chromen-3-yl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one","1-(6-methoxy-2H-chromen-3-yl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one","C585736","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23719279","Chromenylchalcones showing cytotoxicity on human colon cancer cell lines and in silico docking with aurora kinases.","23719279",40]
["1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-4-(4-(4-(methanesulfonyl)piperazin-1-yl)phenyl)-N,N-dimethylpyrrolidin-3-amine","1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-4-(4-(4-(methanesulfonyl)piperazin-1-yl)phenyl)-N,N-dimethylpyrrolidin-3-amine","C000621531","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28254486","SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding.","28254486",40]
["1-(7-methoxy-1H-indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol","1-(7-methoxy-1H-indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol","C579251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24399725","Binding of new aminopropan-2-ol compounds to bovine serum albumin, α1-acid glycoprotein and rat serum using equilibrium dialysis and LC/MS/MS.","24399725",40]
["1-(8-(2-(4-isobutylphenyl)propionyl)octyl)-3-N,N-dimethylcarbamoyl pyridinium bromide","1-(8-(2-(4-isobutylphenyl)propionyl)octyl)-3-N,N-dimethylcarbamoyl pyridinium bromide","C500313","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17630191","IBU-octyl-cytisine, a novel bifunctional compound eliciting anti-inflammatory and cholinergic activity, ameliorates CNS inflammation by inhibition of T-cell activity.","17630191",40]
["1-(8-(hydroxymethyl)-1-(2-(2-methylpyrrolidin-1-yl)ethyl)-4,4a,7,8,9,9a-hexahydroindolo(1,14-fg)quinolin-6(1H)-yl)ethanone","1-(8-(hydroxymethyl)-1-(2-(2-methylpyrrolidin-1-yl)ethyl)-4,4a,7,8,9,9a-hexahydroindolo(1,14-fg)quinolin-6(1H)-yl)ethanone","C000596168","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24850792","Ergoline-derived inverse agonists of the human h3 receptor for the treatment of narcolepsy.","24850792",40]
["1-(aminooxy)-4-((3-nitro-2-pyridyl)dithio)butane","1-(aminooxy)-4-((3-nitro-2-pyridyl)dithio)butane","C069105","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2095214","Synthesis of 1-(aminooxy)-4-[(3-nitro-2-pyridyl)dithio]butane and 1-(aminooxy)-4-[(3-nitro-2-pyridyl)dithio]but-2-ene, novel heterobifunctional cross-linking reagents.","2095214",40]
["1-(benzo(d)(1,2,3)thiadiazol-6-yl)-3-(2-cyclohexenylethyl)urea","1-(benzo(d)(1,2,3)thiadiazol-6-yl)-3-(2-cyclohexenylethyl)urea","C576979","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22795084","An allosteric inhibitor of protein arginine methyltransferase 3.","22795084",40]
["1-(benzofuran-2-yl)-2-propylaminopentane","1-(benzofuran-2-yl)-2-propylaminopentane","C404200","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2003,"14659999","Transporter-mediated actions of R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane.","14659999",40]
["1-(benzylamino)ethaniminium","1-(benzylamino)ethaniminium","C550369","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19203270","Synthesis, biological evaluation, and docking studies of N-substituted acetamidines as selective inhibitors of inducible nitric oxide synthase.","19203270",40]
["1-(carboxymethylthio)tetradecane","1-(carboxymethylthio)tetradecane","C062078","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2001,"11348458","Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid.","11348458",40]
["1-(chloromethyl)silatrane","1-(chloromethyl)silatrane","C033818","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1993,"8111299","[The immunopharmacodynamics of mival].","8111299",40]
["1-(glucopyranosyl-2'-deoxy-2'-iminomethyl)-2-hydroxybenzene","1-(glucopyranosyl-2'-deoxy-2'-iminomethyl)-2-hydroxybenzene","C553910","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20521836","Nanofibers formed through pi...pi stacking of the complexes of glucosyl-C2-salicyl-imine and phenylalanine: characterization by microscopy, modeling by molecular mechanics, and interaction by alpha-helical and beta-sheet proteins.","20521836",40]
["1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester","1-(methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-1H-indene-2-carboxylic acid ethyl ester","C513115","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2010,"19896472","Anti-allergic function and regulatory mechanisms of KR62980 in allergen-induced airway inflammation.","19896472",40]
["1-(N-(2-hydroxy-5-azidobenzoyl)-2-aminoethyl)-4-(N-hydroxysuccinimidyl)succinate","1-(N-(2-hydroxy-5-azidobenzoyl)-2-aminoethyl)-4-(N-hydroxysuccinimidyl)succinate","C047401","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2249696","Radiolabel-transfer cross-linking demonstrates that protein 4.1 binds to the N-terminal region of beta spectrin and to actin in binary interactions.","2249696",40]
["1-(N-methyl-4,4'-bipyridinium)-1-(2-hydroxy-5-nitrophenyl)methane","1-(N-methyl-4,4'-bipyridinium)-1-(2-hydroxy-5-nitrophenyl)methane","C066054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1990,"2215477","The importance of electrostatic interactions in the binding of paraquat to its elicited monoclonal antibody.","2215477",40]
["1-(para-menthen-6-yl)-1-propanone","1-(para-menthen-6-yl)-1-propanone","C000589219","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24246181","Fragrance material review on 1-(para-menthen-6-yl)-1-propanone.","24246181",40]
["1-(phenylazophenylazo)-2-naphthol","1-(phenylazophenylazo)-2-naphthol","C525114","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"17598027","In vitro dermal absorption and metabolism of D&amp;C red no. 17 in human and porcineskin.","17598027",40]
["1-(quinoxalin-6-ylcarbonyl)piperidine","1-(quinoxalin-6-ylcarbonyl)piperidine","C097396","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2006,"17069542","Effect of CX516, an AMPA-modulating compound, on cognition and behavior in fragile X syndrome: a controlled trial.","17069542",40]
["1-(quinoxalin-6-ylcarbonyl)piperidine","1-(quinoxalin-6-ylcarbonyl)piperidine","C097396","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23999288","Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain.","23999288",40]
["1,(N2)-ethenoguanine","1,(N2)-ethenoguanine","C085534","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12016206","1,N(2)-ethenoguanine, a mutagenic DNA adduct, is a primary substrate of Escherichia coli mismatch-specific uracil-DNA glycosylase and human alkylpurine-DNA-N-glycosylase.","12016206",40]
["1,1'-((4,4,7,7-tetramethyl)-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-oxazole)-2-methylidene)quinolinium","1,1'-((4,4,7,7-tetramethyl)-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-oxazole)-2-methylidene)quinolinium","C075296","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25711531","Assays for the determination of the activity of DNA nucleases based on the fluorometric properties of the YOYO dye.","25711531",40]
["1,1'-((4,4,7,7-tetramethyl)-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-oxazole)-2-methylidene)quinolinium","1,1'-((4,4,7,7-tetramethyl)-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-oxazole)-2-methylidene)quinolinium","C075296","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26612254","Detection of amyloid-β fibrils using the DNA-intercalating dye YOYO-1: Binding mode and fibril formation kinetics.","26612254",40]
["1,1'-((propane-1,3-diyl)dioxy)bis(7-methoxy-2-methylidene-1,2,3,10,11,11a-hexahydro-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5,11-dione)","1,1'-((propane-1,3-diyl)dioxy)bis(7-methoxy-2-methylidene-1,2,3,10,11,11a-hexahydro-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5,11-dione)","C423343","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15122070","Preliminary pharmacokinetic and bioanalytical studies of SJG-136 (NSC 694501), a sequence-selective pyrrolobenzodiazepine dimer DNA-cross-linking agent.","15122070",40]
["1,1'-((propane-1,3-diyl)dioxy)bis(7-methoxy-2-methylidene-1,2,3,10,11,11a-hexahydro-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5,11-dione)","1,1'-((propane-1,3-diyl)dioxy)bis(7-methoxy-2-methylidene-1,2,3,10,11,11a-hexahydro-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5,11-dione)","C423343","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16730244","LC-MS/MS assay and dog pharmacokinetics of the dimeric pyrrolobenzodiazepine SJG-136 (NSC 694501).","16730244",40]
["1,1'-((propane-1,3-diyl)dioxy)bis(7-methoxy-2-methylidene-1,2,3,10,11,11a-hexahydro-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5,11-dione)","1,1'-((propane-1,3-diyl)dioxy)bis(7-methoxy-2-methylidene-1,2,3,10,11,11a-hexahydro-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5,11-dione)","C423343","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2004,"15374993","The novel sequence-specific DNA cross-linking agent SJG-136 (NSC 694501) has potent and selective in vitro cytotoxicity in human B-cell chronic lymphocytic leukemia cells with evidence of a p53-independent mechanism of cell kill.","15374993",40]
["1,1'-(4,4,7,7-tetramethyl-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-thiazole)-2-methylidene)quinolinium","1,1'-(4,4,7,7-tetramethyl-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-thiazole)-2-methylidene)quinolinium","C075295","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7969200","Use of stable dye-DNA intercalating complexes to detect cystic fibrosis mutations.","7969200",40]
["1,1',1'',1'''-(ethylenedinitrilo)tetra-2-propanol","1,1',1'',1'''-(ethylenedinitrilo)tetra-2-propanol","C010629","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21968659","Clinical evidence for the activity of tetrahydroxypropyl ethylenediamine (THPE), a new anti-aging active cosmetic.","21968659",40]
["1,1,1,2-tetrafluoro-2-chloroethane","1,1,1,2-tetrafluoro-2-chloroethane","C072959","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1446014","Pentahaloethane-based chlorofluorocarbon substitutes and halothane: correlation of in vivo hepatic protein trifluoroacetylation and urinary trifluoroacetic acid excretion with calculated enthalpies of activation.","1446014",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C515,B515)","v":"1,1,1-trichloroethane"},"1,1,1-trichloroethane","C024566","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J515,K515)","v":"Dermatitis, Allergic Contact"},"D017449","Dermatitis, Allergic Contact",0,2,2001,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q515,Q515)","v":"11553122"},"Occupational allergic contact dermatitis from methyl chloroform (1,1,1-trichloroethane)?","11553122",40]
["1,1,1-trichloroethane","1,1,1-trichloroethane","C024566","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1838318","Occupational allergic contact dermatitis from methyl chloroform (1,1,1-trichloroethane).","1838318",40]
["1,1,1-trichloroethane","1,1,1-trichloroethane","C024566","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1993,"8470120","Contrasting effects of 1,1,1-trichloroethane on [14C]vinyl chloride metabolism and activation in hepatic microsomes from phenobarbital- and isoniazid-treated rats.","8470120",40]
["1,1,2,2-tetrachloroethane","1,1,2,2-tetrachloroethane","C015530","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"6128194","Cytochrome P-450-dependent covalent binding of 1,1,2,2-tetrachloroethane in vitro.","6128194",40]
["1,1',2,2'-tetraoleoylcardiolipin","1,1',2,2'-tetraoleoylcardiolipin","C519576","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28709976","Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center.","28709976",40]
["1,1,2-trichloroethane","1,1,2-trichloroethane","C024567","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"2426232","1,1,2-Trichloroethane: evidence of genotoxicity from short-term tests.","2426232",40]
["1,1,2-trichloroethane","1,1,2-trichloroethane","C024567","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1982,"7151718","Covalent binding of 14C-1,1,2-trichloroethane to hepatic proteins following acetone pretreatment.","7151718",40]
["1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-N5-(2-phenylpropyl)-N5'-(2-phenylpropyl)-2,2'-binaphthyl-5,5'-dicarboxamide","1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-N5-(2-phenylpropyl)-N5'-(2-phenylpropyl)-2,2'-binaphthyl-5,5'-dicarboxamide","C550162","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20443627","BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.","20443627",40]
["1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-N5-(2-phenylpropyl)-N5'-(2-phenylpropyl)-2,2'-binaphthyl-5,5'-dicarboxamide","1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-N5-(2-phenylpropyl)-N5'-(2-phenylpropyl)-2,2'-binaphthyl-5,5'-dicarboxamide","C550162","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28055968","BH3 mimetics suppress CXCL12 expression in human malignant peripheral nerve sheath tumor cells.","28055968",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"19641517","Oxidation of cell surface thiol groups by contact sensitizers triggers the maturation of dendritic cells.","19641517",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11459471","Synthesis and characterization of a ruthenium(II)-based redox conjugate for reagentless biosensing.","11459471",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11691942","A versatile in vivo footprinting technique using 1,10-phenanthroline-copper complex to study important cellular processes.","11691942",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11714692","An mRNA loop/bulge in the ferritin iron-responsive element forms in vivo and Was detected by radical probing with Cu-1,10-phenantholine and iron regulatory protein footprinting.","11714692",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12237464","Site-specific DNA cleavage of synthetic NarL sites by an engineered Escherichia coli NarL protein-1,10-phenanthroline cleaving agent.","12237464",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17185028","Spectroscopic and theoretical studies on cobalt (II) complex of maleonitriledithiolate and 5-nitro-1,10-phenanthroline.","17185028",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17638338","Synthesis and DNA binding/cleavage of mononuclear copper(II) phenanthroline/bipyridine proline complexes.","17638338",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19378167","Footprinting DNA-protein interactions in native polyacrylamide gels by chemical nucleolytic activity of 1,10-phenanthroline-copper.","19378167",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21910144","Identification of [PtCl2(phen)] binding modes in amyloid-β peptide and the mechanism of aggregation inhibition.","21910144",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22446765","Study on the interaction of silver(I) complex with bovine serum albumin by spectroscopic techniques.","22446765",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2723627","Kinetic evidence for cooperative binding of two ortho-phenanthroline molecules to astacus protease during metal removal.","2723627",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27571992","DNA binding, DNA cleavage and HSA interaction of several metal complexes containing N-(2-hydroxyethyl)-N'-benzoylthiourea and 1,10-phenanthroline ligands.","27571992",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28616784","Synthesis, X-ray crystal structure, DNA/BSA binding, DNA cleavage and cytotoxicity studies of phenanthroline based copper(II)/zinc(II) complexes.","28616784",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3342923","Interaction of neocuproine, 1,10-phenanthroline and 2,2'-dipyridyl with human ceruloplasmin.","3342923",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7309756","Cross-linking of hemoglobin to the cytoplasmic surface of human erythrocyte membranes. Identification of band 3 as a site for hemoglobin binding in Cu2+-o-phenanthroline catalyzed cross-linking.","7309756",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8004214","1,10-Phenanthroline-copper ion nuclease footprinting of DNA-protein complexes in situ following mobility-shift electrophoresis assays.","8004214",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1747067","Protective effect of O-phenanthroline against mechlorethamine toxicity in the rat liver slice system and in the guinea pig skin.","1747067",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2009,"19683366","Cytotoxicity and effects of 1,10-phenanthroline and 5-amino-1,10-phenanthroline derivatives on some immunocompetent cells.","19683366",40]
["1,10-phenanthroline","1,10-phenanthroline","C025205","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1997,"9111069","Role of oxidative stress in the action of vanadium phosphotyrosine phosphatase inhibitors. Redox independent activation of NF-kappaB.","9111069",40]
["1,12-benzoperylene","1,12-benzoperylene","C006718","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1993,"8425261","32P-postlabelling analysis of the covalent binding of benzo[ghi]perylene to DNA in vivo and in vitro.","8425261",40]
["1,12-bis(4-methyl-5-(2-hydroxyethyl)thiazol-3-ium-3-yl)dodecane","1,12-bis(4-methyl-5-(2-hydroxyethyl)thiazol-3-ium-3-yl)dodecane","C499114","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15637133","Quantification of antimalarial bisthiazolium compounds and their neutral bioprecursors in plasma by liquid chromatography-electrospray mass spectrometry.","15637133",40]
["1,12-bis(4-methyl-5-(2-hydroxyethyl)thiazol-3-ium-3-yl)dodecane","1,12-bis(4-methyl-5-(2-hydroxyethyl)thiazol-3-ium-3-yl)dodecane","C499114","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25470252","A chemical proteomics approach for the search of pharmacological targets of the antimalarial clinical candidate albitiazolium in Plasmodium falciparum using photocrosslinking and click chemistry.","25470252",40]
["1,12-bis(4-methyl-5-(2-methoxyethyl)thiazol-3-ium-3-yl)dodecane","1,12-bis(4-methyl-5-(2-methoxyethyl)thiazol-3-ium-3-yl)dodecane","C499115","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15637133","Quantification of antimalarial bisthiazolium compounds and their neutral bioprecursors in plasma by liquid chromatography-electrospray mass spectrometry.","15637133",40]
["1,15-bis(ethylamino)-4,8,12-triazapentadecane","1,15-bis(ethylamino)-4,8,12-triazapentadecane","C094172","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17887793","Polyamine analogues bind human serum albumin.","17887793",40]
["1,1-azobisformamide","1,1-azobisformamide","C004525","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,1999,"10426321","Azodicarbonamide inhibits T-cell responses in vitro and in vivo.","10426321",40]
["1,1-azobisformamide","1,1-azobisformamide","C004525","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2001,"11414742","Azodicarbonamide as a new T cell immunosuppressant: synergy with cyclosporin A.","11414742",40]
["1,1-azobisformamide","1,1-azobisformamide","C004525","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,1999,"10426321","Azodicarbonamide inhibits T-cell responses in vitro and in vivo.","10426321",40]
["1,1-azobisformamide","1,1-azobisformamide","C004525","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"2972529","Contact dermatitis from azodicarbonamide in earplugs.","2972529",40]
["1,1-azobisformamide","1,1-azobisformamide","C004525","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2011,"21669231","Lopinavir shows greater specificity than zinc finger ejecting compounds as a potential treatment for human papillomavirus-related lesions.","21669231",40]
["1,1-azobisformamide","1,1-azobisformamide","C004525","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24164050","An in silico appraisal of azoic and disulphide derivatives for anticancer activity against HPV E6 oncoprotein to medicate cervical cancer.","24164050",40]
["1,1-azobisformamide","1,1-azobisformamide","C004525","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"28734852","Azodicarbonamide (ADCA): A reconsideration of classification as a respiratory sensitiser.","28734852",40]
["1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane","1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane","C534880","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23950896","Chemoprevention of skin cancer with 1,1-Bis (3'-indolyl)-1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1).","23950896",40]
["1,1-bis(4-chlorophenyl)chloromethane","1,1-bis(4-chlorophenyl)chloromethane","C026310","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1980,"6447017","Occupational contact allergy to bis-(4-chlorophenyl)-methyl chloride.","6447017",40]
["1,1-cyclopropanediol","1,1-cyclopropanediol","C018885","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"6998494","Kinetics of the reaction of cyclopropanone hydrate with yeast aldehyde dehydrogenase: a model for enzyme--substrate interaction.","6998494",40]
["1,1-cyclopropanediol","1,1-cyclopropanediol","C018885","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"7076673","Mechanism of inhibition of horseradish peroxidase by cyclopropanone hydrate.","7076673",40]
["1,1'-decamethylenebis-4-aminoquinaldinium di-iodide","1,1'-decamethylenebis-4-aminoquinaldinium di-iodide","C500008","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15252133","The receptor for activated C-kinase-I (RACK-I) anchors activated PKC-beta on melanosomes.","15252133",40]
["1,1-dichloro-2,3-diphenyl-2-(4-methoxyphenyl)cyclopropane","1,1-dichloro-2,3-diphenyl-2-(4-methoxyphenyl)cyclopropane","C075421","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1993,"8369524","The influence of a novel cyclopropyl antiestrogen (compound 7a) on human breast cancer cells in culture.","8369524",40]
["1,1'-dideoxygossypol","1,1'-dideoxygossypol","C094630","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7608907","Synthesis and anti-HIV activity of 1,1'-dideoxygossypol and related compounds.","7608907",40]
["1,1-dimethyl-2-phenylethyl acetate","1,1-dimethyl-2-phenylethyl acetate","C577702","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22445843","Fragrance material review on 1,1-dimethyl-2-phenylethyl acetate.","22445843",40]
["1,1-dimethyl-2-phenylethyl butyrate","1,1-dimethyl-2-phenylethyl butyrate","C577723","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22414645","Fragrance material review on 1,1-dimethyl-2-phenylethyl butyrate.","22414645",40]
["1,1-dimethyl-2-phenylethyl formate","1,1-dimethyl-2-phenylethyl formate","C577714","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22406573","Fragrance material review on 1,1-dimethyl-2-phenylethyl formate.","22406573",40]
["1,1-dimethyl-2-phenylethyl isobutyrate","1,1-dimethyl-2-phenylethyl isobutyrate","C577703","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22406566","Fragrance material review on 1,1-dimethyl-2-phenylethyl isobutyrate.","22406566",40]
["1,1-dimethyl-2-phenylethyl propionate","1,1-dimethyl-2-phenylethyl propionate","C577684","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22406559","Fragrance material review on 1,1-dimethyl-2-phenylethyl propionate.","22406559",40]
["1,1-dimethylallyl caffeic acid ester","1,1-dimethylallyl caffeic acid ester","C054126","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1989,"2598655","Propolis allergy: synthesis and patch testing of gamma,gamma-dimethylallyl caffeic acid ester and its o-methyl derivatives.","2598655",40]
["1,1-dimethylallyl caffeic acid ester","1,1-dimethylallyl caffeic acid ester","C054126","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1987,"3677659","Propolis allergy. (II). The sensitizing properties of 1,1-dimethylallyl caffeic acid ester.","3677659",40]
["1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","C432747","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2007,"17537989","Anti-inflammatory property of the cannabinoid receptor-2-selective agonist JWH-133 in a rodent model of autoimmune uveoretinitis.","17537989",40]
["1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","C432747","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2007,"17537989","Anti-inflammatory property of the cannabinoid receptor-2-selective agonist JWH-133 in a rodent model of autoimmune uveoretinitis.","17537989",40]
["1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","C432747","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"16111718","The cannabinoid CB2 receptor selective agonist JWH133 reduces mast cell oedema in response to compound 48/80 in vivo but not the release of beta-hexosaminidase from skin slices in vitro.","16111718",40]
["1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","C432747","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17276894","Temporal variation in CB2R levels following T lymphocyte activation: evidence that cannabinoids modulate CXCL12-induced chemotaxis.","17276894",40]
["1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","C432747","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2008,"18037503","Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis.","18037503",40]
["1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","C432747","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22119709","Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis.","22119709",40]
["1,1-diphenyl-2-picrylhydrazyl","1,1-diphenyl-2-picrylhydrazyl","C004931","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"11055395","Kurosu, a traditional vinegar produced from unpolished rice, suppresses lipid peroxidation in vitro and in mouse skin.","11055395",40]
["1,1-diphenyl-2-picrylhydrazyl","1,1-diphenyl-2-picrylhydrazyl","C004931","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2001,"11355772","Cancer chemopreventive activities of S-3-1, a synthetic derivative of danshinone.","11355772",40]
["1,1-ethylenebis(1-nitrosourea)","1,1-ethylenebis(1-nitrosourea)","C014541","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1983,"6609734","[Effects of ethylenebisnitrosourea on the functions of murine lymphocytes].","6609734",40]
["1,2,3,4,6,7,8-heptachlorodibenzodioxin","1,2,3,4,6,7,8-heptachlorodibenzodioxin","C046839","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1987,"3492063","Mechanisms of 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HpCDD)-induced humoral immune suppression: evidence of primary defect in T-cell regulation.","3492063",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C579,B579)","v":"1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta(b)(1,4)diazepino(6,7,1hj)indole"},"1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta(b)(1,4)diazepino(6,7,1hj)indole","C501656","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J579,K579)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q579,Q579)","v":"15705738"},"WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity.","15705738",40]
["1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline","1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline","C084924","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20067570","1-Benzyl-1,2,3,4-tetrahydroisoquinoline binds with tubulin beta, a substrate of parkin, and reduces its polyubiquitination.","20067570",40]
["1,2,3,4-tetrahydro-1-phenylisoquinoline","1,2,3,4-tetrahydro-1-phenylisoquinoline","C096775","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22415658","Synthesis and biological evaluation of 1-phenyl-1,2,3,4-dihydroisoquinoline compounds as tubulin polymerization inhibitors.","22415658",40]
["1,2,3,4-tetrahydro-7-methoxyisoquinoline-3-carboxylic acid","1,2,3,4-tetrahydro-7-methoxyisoquinoline-3-carboxylic acid","C444259","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11701008","Total syntheses of conformationally constrained didemnin B analogues. replacements of N,O-dimethyltyrosine with L-1,2,3,4-tetrahydroisoquinoline and L-1,2,3,4-tetrahydro-7-methoxyisoquinoline.","11701008",40]
["1,2,3,4-tetrahydroisoquinoline","1,2,3,4-tetrahydroisoquinoline","C014843","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10218820","1,2,3,4-tetrahydroisoquinoline derivatives: a new class of 5-HT1A receptor ligands.","10218820",40]
["1,2,3,4-tetrahydroisoquinoline","1,2,3,4-tetrahydroisoquinoline","C014843","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11701008","Total syntheses of conformationally constrained didemnin B analogues. replacements of N,O-dimethyltyrosine with L-1,2,3,4-tetrahydroisoquinoline and L-1,2,3,4-tetrahydro-7-methoxyisoquinoline.","11701008",40]
["1,2,3,4-tetrahydroisoquinoline","1,2,3,4-tetrahydroisoquinoline","C014843","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2004,"15120584","Effect of 1,2,3,4,-tetrahydroisoquinoline administration under conditions of CYP2D inhibition on dopamine metabolism, level of tyrosine hydroxylase protein and the binding of [3H]GBR 12,935 to dopamine transporter in the rat nigrostriatal, dopaminergic system.","15120584",40]
["1,2,3,4-tetrahydroisoquinoline","1,2,3,4-tetrahydroisoquinoline","C014843","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16386905","1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors.","16386905",40]
["1,2,3,4-tetrahydroisoquinoline","1,2,3,4-tetrahydroisoquinoline","C014843","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2006,"16515537","The mechanism of 1,2,3,4-tetrahydroisoquinolines neuroprotection: the importance of free radicals scavenging properties and inhibition of glutamate-induced excitotoxicity.","16515537",40]
["1,2,3,4-tetrahydroisoquinoline","1,2,3,4-tetrahydroisoquinoline","C014843","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19217289","Atropisomeric small molecule Bcl-2 ligands: determination of bioactive conformation.","19217289",40]
["1,2,3,4-tetrahydroisoquinoline","1,2,3,4-tetrahydroisoquinoline","C014843","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19904002","Treatment with 1,2,3,4,-tetrahydroisoquinoline affects glutamate release in the striatum but not the binding of [3H]MK-801 to NMDA receptors in the dopaminergic structures of the rat brain.","19904002",40]
["1,2,3,4-tetrahydroisoquinoline","1,2,3,4-tetrahydroisoquinoline","C014843","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20598885","Derivatives of tetrahydroisoquinoline: synthesis and initial evaluation of novel non-peptide antagonists of the alpha(IIb)beta(3)-integrin.","20598885",40]
["1,2,3,4-tetrahydroisoquinoline","1,2,3,4-tetrahydroisoquinoline","C014843","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2018,"29656199","Investigating isoindoline, tetrahydroisoquinoline, and tetrahydrobenzazepine scaffolds for their sigma receptor binding properties.","29656199",40]
["1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid","1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid","C078986","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2005,"15951175","1-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid as a Tic mimetic: application in the synthesis of potent human melanocortin-4 receptor selective agonists.","15951175",40]
["1,2,3,4-tetrahydroisoquinoline-7-sulfonamide","1,2,3,4-tetrahydroisoquinoline-7-sulfonamide","C018428","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17845018","Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase.","17845018",40]
["1,2,3,4-tetrahydroquinoline","1,2,3,4-tetrahydroquinoline","C542964","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21115247","Tetrahydroquinoline glucocorticoid receptor agonists: discovery of a 3-hydroxyl for improving receptor selectivity.","21115247",40]
["1,2,3,4-tetrahydroquinoline","1,2,3,4-tetrahydroquinoline","C542964","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"23139415","Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of the cAMP-binding protein Epac.","23139415",40]
["1,2,3,5-thiatriazolidin-3-one 1,1-dioxide","1,2,3,5-thiatriazolidin-3-one 1,1-dioxide","C549117","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20061159","Utilization of the 1,2,3,5-thiatriazolidin-3-one 1,1-dioxide scaffold in the design of potential inhibitors of human neutrophil proteinase 3.","20061159",40]
["1,2,3-trithiane-5-carboxylic acid","1,2,3-trithiane-5-carboxylic acid","C102074","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1996,"8796741","1,2,3-Trithiane-5-carboxylic acid, a first contact allergen from Asparagus officinalis (Liliaceae).","8796741",40]
["1,2,4,5-tetramethoxybenzene","1,2,4,5-tetramethoxybenzene","C088469","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2016,"27355819","1,2,4,5-Tetramethoxybenzene Suppresses House Dust Mite-Induced Allergic Inflammation in BALB/c Mice.","27355819",40]
["1,2,4-triazine","1,2,4-triazine","C093444","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20153202","Synthesis and characterization of novel 1,2,4-triazine derivatives with antiproliferative activity.","20153202",40]
["1,2,4-triazine","1,2,4-triazine","C093444","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25251582","Design, synthesis, and biological evaluation of hydrazone incorporated 1,2,4-triazines as anticonvulsant agents.","25251582",40]
["1,2,4-triazine","1,2,4-triazine","C093444","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2015,"25315866","A mononuclear Ni(II) complex with 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine: DNA- and BSA-binding and anticancer activity against human breast carcinoma cells.","25315866",40]
["1,2,4-triazole","1,2,4-triazole","C045575","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23849879","1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases.","23849879",40]
["1,2,4-triazole","1,2,4-triazole","C045575","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20045337","Synthesis and structure-activity relationship of 1,2,4-triazole-containing diarylpyrazolyl carboxamide as CB1 cannabinoid receptor-ligand.","20045337",40]
["1,2,4-triazole","1,2,4-triazole","C045575","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"22204739","Pyrrolo- and pyrazolo-[3,4-e][1,2,4]triazolo[1,5-c]pyrimidines as adenosine receptor antagonists.","22204739",40]
["1,2,4-triazole","1,2,4-triazole","C045575","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23350742","Synthesis, fungicidal activity, and sterol 14α-demethylase binding interaction of 2-azolyl-3,4-dihydroquinazolines on Penicillium digitatum.","23350742",40]
["1,2,4-triazole","1,2,4-triazole","C045575","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23712380","Design, synthesis and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetohydrazide derivatives with anti-inflammatory-analgesic activities.","23712380",40]
["1,2,4-triazole","1,2,4-triazole","C045575","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24266618","Assessing molecular docking tools for relative biological activity prediction: a case study of triazole HIV-1 NNRTIs.","24266618",40]
["1,2,4-triazole","1,2,4-triazole","C045575","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25435152","New trisubstituted 1,2,4-triazoles as ghrelin receptor antagonists.","25435152",40]
["1,2,4-triazolo(4,3-a)quinoxaline","1,2,4-triazolo(4,3-a)quinoxaline","C469661","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18468446","Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.","18468446",40]
["1,2,5,6-dibenzanthracene","1,2,5,6-dibenzanthracene","C026486","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1953,"13042814","The interaction of carcinogenic hydrocarbons with tissue constituents.  II.  1,2,5,6-Dibenzanthracene-9,10-C14 in skin.","13042814",40]
["1,2,5-thiadiazolidin-3-one 1,1-dioxide","1,2,5-thiadiazolidin-3-one 1,1-dioxide","C428430","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11361013","1,2,5-Thiadiazolidin-3-one 1,1 dioxide: a powerful scaffold for probing the S' subsites of (chymo)trypsin-like serine proteases.","11361013",40]
["1,2,5-thiadiazolidin-3-one 1,1-dioxide","1,2,5-thiadiazolidin-3-one 1,1-dioxide","C428430","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28345882","Covalent Allosteric Inactivation of Protein Tyrosine Phosphatase 1B (PTP1B) by an Inhibitor-Electrophile Conjugate.","28345882",40]
["1,2,6-hexanetriol","1,2,6-hexanetriol","C400265","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1999,"10445708","Allergic contact dermatitis from 1,2,6-hexanetriol in fluocinonide cream.","10445708",40]
["1,2,7,8-tetrachlorodibenzo-p-dioxin","1,2,7,8-tetrachlorodibenzo-p-dioxin","C445379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16545771","A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo.","16545771",40]
["1,2,9,10-tetramethoxy-7H-dibenzo(de,g)quinolin-7-one","1,2,9,10-tetramethoxy-7H-dibenzo(de,g)quinolin-7-one","C000591894","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2014,"24489654","Discovery of a small molecule agonist of phosphatidylinositol 3-kinase p110α that reactivates latent HIV-1.","24489654",40]
["1,2,9,10-tetramethoxy-7H-dibenzo(de,g)quinolin-7-one","1,2,9,10-tetramethoxy-7H-dibenzo(de,g)quinolin-7-one","C000591894","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2014,"24489654","Discovery of a small molecule agonist of phosphatidylinositol 3-kinase p110α that reactivates latent HIV-1.","24489654",40]
["1,23,25-trihydroxy-24-oxo-vitamin D3","1,23,25-trihydroxy-24-oxo-vitamin D3","C038633","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1997,"9235987","Synthesis, stereochemistry, and biological activity of 1alpha,23,25-trihydroxy-24-oxovitamin D3, a major natural metabolite of 1alpha,25-dihydroxyvitamin D3.","9235987",40]
["1,24,25-trihydroxyvitamin D3","1,24,25-trihydroxyvitamin D3","C013721","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3602141","Isolation of vitamin D3 metabolites from Solanum malacoxylon leaf extracts incubated with ruminal fluid.","3602141",40]
["1,24-dihydroxy-25-nitrovitamin D3","1,24-dihydroxy-25-nitrovitamin D3","C118930","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10091688","Synthesis and biological evaluation of 1alpha,24-dihydroxy-25-nitrovitamin D3.","10091688",40]
["1,24-dihydroxyvitamin D2","1,24-dihydroxyvitamin D2","C063087","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2154251","1 alpha-hydroxylation of 24-hydroxyvitamin D2 represents a minor physiological pathway for the activation of vitamin D2 in mammals.","2154251",40]
["1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3","1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3","C408047","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2000,"10772887","Potent inhibition of dendritic cell differentiation and maturation by vitamin D analogs.","10772887",40]
["1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3","1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3","C408047","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"10772887","Potent inhibition of dendritic cell differentiation and maturation by vitamin D analogs.","10772887",40]
["1,25,26-trihydroxyvitamin D3","1,25,26-trihydroxyvitamin D3","C030049","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24492588","Synthesis and biological activity of 1α,2α,25-trihydroxyvitamin D3: active metabolite of 2α-(3-hydroxypropoxy)-1α,25-dihydroxyvitamin D3 by human CYP3A4.","24492588",40]
["1,25-dihydroxy-19-norvitamin D3","1,25-dihydroxy-19-norvitamin D3","C083610","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12968893","Efficient synthesis of 2-modified 1alpha,25-dihydroxy-19-norvitamin D3 with Julia olefination: high potency in induction of differentiation on HL-60 cells.","12968893",40]
["1,25-dihydroxy-19-norvitamin D3","1,25-dihydroxy-19-norvitamin D3","C083610","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17110116","Structure-activity relationships of 19-norvitamin D analogs having a fluoroethylidene group at the C-2 position.","17110116",40]
["1,25-dihydroxy-19-norvitamin D3","1,25-dihydroxy-19-norvitamin D3","C083610","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27629592","Synthesis of 2α- and 2β-(3-hydroxypropyl)- 7,8-cis-14-epi-1α,25-dihydroxy-19-norvitamin D3 and their biological activity.","27629592",40]
["1,25-dihydroxy-21-(3-hydroxy-3-methylbutyl)vitamin D(3)","1,25-dihydroxy-21-(3-hydroxy-3-methylbutyl)vitamin D(3)","C411462","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17218092","Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation.","17218092",40]
["1,25-dihydroxy-21-(3-hydroxy-3-methylbutyl)vitamin D(3)","1,25-dihydroxy-21-(3-hydroxy-3-methylbutyl)vitamin D(3)","C411462","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26473302","A spectroscopic and molecular dynamic approach on the interaction between ionic liquid type gemini surfactant and human serum albumin.","26473302",40]
["1,25-dihydroxy-26-(hydroxymethyl)-26-methylvitamin D3","1,25-dihydroxy-26-(hydroxymethyl)-26-methylvitamin D3","C560303","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21524075","Synthesis and biological evaluation of 1α,25-dihydroxyvitamin D(3) analogues hydroxymethylated at C-26.","21524075",40]
["1,25-dihydroxy-26-(hydroxymethyl)vitamin D3","1,25-dihydroxy-26-(hydroxymethyl)vitamin D3","C560304","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21524075","Synthesis and biological evaluation of 1α,25-dihydroxyvitamin D(3) analogues hydroxymethylated at C-26.","21524075",40]
["1,25-dihydroxy-5,6-16-ene-vitamin D3","1,25-dihydroxy-5,6-16-ene-vitamin D3","C458880","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2002,"12064463","Signaling of monocytic differentiation by a non-hypercalcemic analog of vitamin D3, 1,25(OH)2-5,6 trans-16-ene-vitamin D3, involves nuclear vitamin D receptor (nVDR) and non-nVDR-mediated pathways.","12064463",40]
["1,25-dihydroxyergocalciferol","1,25-dihydroxyergocalciferol","C003564","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2017,"28617989","1,25-dihydroxyvitamin D3 -induced dendritic cells suppress experimental autoimmune encephalomyelitis by increasing proportions of the regulatory lymphocytes and reducing T helper type 1 and type 17 cells.","28617989",40]
["1,25-dihydroxyergocalciferol","1,25-dihydroxyergocalciferol","C003564","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2006,"16516540","Evidence for the activation of 1alpha-hydroxyvitamin D2 by 25-hydroxyvitamin D-24-hydroxylase: delineation of pathways involving 1alpha,24-dihydroxyvitamin D2 and 1alpha,25-dihydroxyvitamin D2.","16516540",40]
["1,25-dihydroxyergocalciferol","1,25-dihydroxyergocalciferol","C003564","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2154251","1 alpha-hydroxylation of 24-hydroxyvitamin D2 represents a minor physiological pathway for the activation of vitamin D2 in mammals.","2154251",40]
["1,25-dihydroxyergocalciferol","1,25-dihydroxyergocalciferol","C003564","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2547343","Comparison of receptor binding, biological activity, and in vivo tracer kinetics for 1,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D2, and its 24 epimer.","2547343",40]
["1,25-dihydroxyergocalciferol","1,25-dihydroxyergocalciferol","C003564","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3495200","Synthesis of 25-hydroxy-[26,27-3H]vitamin D2, 1,25-dihydroxy-[26,27-3H]vitamin D2 and their (24R)-epimers.","3495200",40]
["1,25-dihydroxyergocalciferol","1,25-dihydroxyergocalciferol","C003564","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"26760999","Antiproliferative Activity of Double Point Modified Analogs of 1,25-Dihydroxyvitamin D₂ Against Human Malignant Melanoma Cell Lines.","26760999",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,3,2011,"22044285","1,25-Dihydroxyvitamin D3 inhibits proliferation but not the suppressive function of regulatory T cells in the absence of antigen-presenting cells.","22044285",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2012,"22592096","Correlation of increases in 1,25-dihydroxyvitamin D during vitamin D therapy with activation of CD4+ T lymphocytes in HIV-1-infected males.","22592096",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2015,"25940772","Vitamin D controls apoptosis and proliferation of cutaneous T-cell lymphoma cells.","25940772",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2012,"21849106","Vitamin D and immune function: an overview.","21849106",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2016,"27703987","Immunomodulatory Effects of 1,25-Dihydroxyvitamin D3 on Dendritic Cells Promote Induction of T Cell Hyporesponsiveness to Myelin-Derived Antigens.","27703987",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C643,B643)","v":"1,25-dihydroxyvitamin D"},"1,25-dihydroxyvitamin D","C097949","3_KE",398,3,"Dendritic Cells","Activation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J643,K643)","v":"Dendritic Cells"},"D003713","Dendritic Cells",1,1,2003,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q643,Q643)","v":"12520519"},"Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases.","12520519",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"20124438","Regulation of calcium signaling in dendritic cells by 1,25-dihydroxyvitamin D3.","20124438",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2012,"22103328","Differential protein pathways in 1,25-dihydroxyvitamin d(3) and dexamethasone modulated tolerogenic human dendritic cells.","22103328",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2013,"23966330","Vitamin D regulates the gut microbiome and protects mice from dextran sodium sulfate-induced colitis.","23966330",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2012,"22854622","1,25-dihydroxyvitamin D exerts similar immunosuppressive effects as UVR but is dispensable for local UVR-induced immunosuppression.","22854622",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2012,"23187109","UVB immunosuppression: vitamin D or not vitamin D? That is the question.","23187109",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1999,"10479287","Synthesis, biological activity, and conformational analysis of four seco-D-15,19-bisnor-1alpha,25-dihydroxyvitamin D analogues, diastereomeric at C17 and C20.","10479287",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2004,"15225800","Calcium and 1,25(OH)2D: interacting drivers of epidermal differentiation.","15225800",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2001,"11710940","Inhibition of 1,25-dihydroxyvitamin-D-induced keratinocyte differentiation by blocking the expression of phospholipase C-gamma1.","11710940",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2003,"12520529","Vitamin D regulated keratinocyte differentiation: role of coactivators.","12520529",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2014,"25207372","The vitamin D receptor: a tumor suppressor in skin.","25207372",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1996,"8707874","In vivo effects of vitamin D on the proliferation and differentiation of rat keratinocytes.","8707874",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2000,"10973809","Characterization of 25-hydroxyvitamin D binding protein from intestinal cells.","10973809",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11149488","The unique tryptophan residue of the vitamin D receptor is critical for ligand binding and transcriptional activation.","11149488",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16059639","Enhanced coactivator binding and transcriptional activation of mutant vitamin D receptors from patients with hereditary 1,25-dihydroxyvitamin D-resistant rickets by phosphorylation and vitamin D analogs.","16059639",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21898591","1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase.","21898591",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22292037","Vitamin D binding protein and monocyte response to 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D: analysis by mathematical modeling.","22292037",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24094638","Determination of vitamin D and its metabolites.","24094638",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2003,"12520519","Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases.","12520519",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2010,"20211254","Regulatory T cell function correlates with serum 25-hydroxyvitamin D, but not with 1,25-dihydroxyvitamin D, parathyroid hormone and calcium levels in patients with relapsing remitting multiple sclerosis.","20211254",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2012,"21849106","Vitamin D and immune function: an overview.","21849106",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2013,"23611825","Cholecalciferol supplementation in HIV-infected youth with vitamin D insufficiency: effects on vitamin D status and T-cell phenotype: a randomized controlled trial.","23611825",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2013,"23845396","Vitamin D in autoimmune liver disease.","23845396",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"25716808","[Current Topics on Vitamin D. The effects of vitamin D on the immune system].","25716808",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2016,"27703987","Immunomodulatory Effects of 1,25-Dihydroxyvitamin D3 on Dendritic Cells Promote Induction of T Cell Hyporesponsiveness to Myelin-Derived Antigens.","27703987",40]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2017,"29061851","Hormonal vitamin D upregulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in human but not mouse.","29061851",40]
["1,25-dihydroxyvitamin D3-26,23-lactone","1,25-dihydroxyvitamin D3-26,23-lactone","C026947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6091549","Biological activity assessment of the 26,23-lactones of 1,25-dihydroxyvitamin D3 and 25-hydroxyvitamin D3 and their binding properties to chick intestinal receptor and plasma vitamin D binding protein.","6091549",40]
["1,25-dihydroxyvitamin D3-26,23-lactone","1,25-dihydroxyvitamin D3-26,23-lactone","C026947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6572492","Biological activity of 24,24-difluoro-1 alpha, 25-dihydroxyvitamin D3 and 1 alpha, 25-dihydroxyvitamin D3-26,23-lactone in inducing differentiation of human myeloid leukemia cells.","6572492",40]
["1,25-dihydroxyvitamin D3-3-bromoacetate","1,25-dihydroxyvitamin D3-3-bromoacetate","C104313","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1999,"10496974","Mechanistic studies to evaluate the enhanced antiproliferation of human keratinocytes by 1alpha,25-dihydroxyvitamin D(3)-3-bromoacetate, a covalent modifier of vitamin D receptor, compared to 1alpha,25-dihydroxyvitamin D(3).","10496974",40]
["1,25-dihydroxyvitamin D3-3-bromoacetate","1,25-dihydroxyvitamin D3-3-bromoacetate","C104313","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2003,"12874825","1alpha,25-Dihydroxyvitamin D3-3beta-(2)-bromoacetate, an affinity labeling derivative of 1alpha,25-dihydroxyvitamin D3 displays strong antiproliferative and cytotoxic behavior in prostate cancer cells.","12874825",40]
["1,25-dihydroxyvitamin D3-3-bromoacetate","1,25-dihydroxyvitamin D3-3-bromoacetate","C104313","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2004,"15585637","Inhibition of proliferation and induction of apoptosis by 25-hydroxyvitamin D3-3beta-(2)-Bromoacetate, a nontoxic and vitamin D receptor-alkylating analog of 25-hydroxyvitamin D3 in prostate cancer cells.","15585637",40]
["1,25-dihydroxyvitamin D3-3-bromoacetate","1,25-dihydroxyvitamin D3-3-bromoacetate","C104313","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23314787","1α,25-Dihydroxyvitamin-D3-3-bromoacetate regulates AKT/mTOR signaling cascades: a therapeutic agent for psoriasis.","23314787",40]
["1,25-dihydroxyvitamin D3-3-bromoacetate","1,25-dihydroxyvitamin D3-3-bromoacetate","C104313","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"24036370","1,25-Dihydroxyvitamin D3-3-bromoacetate, a novel vitamin D analog induces immunosuppression through PI3K/Akt/mTOR signaling cascade.","24036370",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2017,"27343839","Cross-reactivity between methylisothiazolinone, octylisothiazolinone and benzisothiazolinone using a modified local lymph node assay.","27343839",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2017,"27343839","Cross-reactivity between methylisothiazolinone, octylisothiazolinone and benzisothiazolinone using a modified local lymph node assay.","27343839",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1999,"10048662","Pulpitis of the fingers from a shoe glue containing 1,2-benzisothiazolin-3-one (BIT).","10048662",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1999,"10073443","Skin sensitization risk assessment: a comparative evaluation of 3 isothiazolinone biocides.","10073443",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"12786737","Occupational allergic contact dermatitis from 1,2-benzisothiazolin-3-one without cross-sensitization to other isothiazolinones.","12786737",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1992,"1451483","Occupational contact allergy to 1,2-benzisothiazolin-3-one in the manufacture of air fresheners.","1451483",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1992,"1451508","Allergic contact dermatitis due to 1,2-benzisothiazolin-3-one in paint manufacture.","1451508",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2004,"15128326","Occupational allergic contact dermatitis caused by 1,2-benzisothiazolin-3-one in a varnish maker, followed by sensitization to benzalkonium chloride in Oilatum Plus bath additive.","15128326",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"16033407","Occupational contact dermatitis to 1,2-benzisothiazolin-3-one and 5-chloro-2-methylisothiazolin-3-one/2-methylisothiazolin-3-one in paint manufacturers.","16033407",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2007,"17988285","1,2-benzisothiazolin-3-one in disposable polyvinyl chloride gloves for medical use.","17988285",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2009,"19780781","Allergic contact dermatitis to 1,2-benzisothiazolin-3-one in the water softener manufacturing industry.","19780781",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,1,2012,"23039006","Systemic allergic dermatitis following airborne exposure to 1,2-benzisothiazolin-3-one.","23039006",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2013,"23429043","Estimation of the safe use concentrations of the preservative 1,2-benzisothiazolin-3-one (BIT) in consumer cleaning products and sunscreens.","23429043",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2013,"24117738","Methylisothiazolinone contact allergy--growing epidemic.","24117738",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2014,"24815516","The dramatic increase in the rate of methylisothiazolinone contact allergy in Belgium: a multicentre study.","24815516",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2014,"25141913","Occupations at risk of developing contact allergy to isothiazolinones in Danish contact dermatitis patients: results from a Danish multicentre study (2009-2012).","25141913",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2015,"25711162","Concomitant reactivity to methylisothiazolinone, benzisothiazolinone, and octylisothiazolinone. International Network of Departments of Dermatology data, 2009-2013.","25711162",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2015,"25880799","Occupational contact dermatitis caused by N-butyl-1,2-benzisothiazolin-3-one in a cutting fluid.","25880799",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2016,"27709698","Contact allergy to 1,2-benzisothiazolin-3-one.","27709698",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2017,"27862003","Occurrence and concentrations of isothiazolinones in detergents and cosmetics in Switzerland.","27862003",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2017,"27957753","Occupational allergic contact dermatitis caused by benzisothiazolinone in printing ink and soap.","27957753",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1993,"8428460","1,2-benzisothiazolin-3-one.","8428460",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1997,"9046655","Allergic contact dermatitis to 1,2-benzisothiazolin-3-one in the carpet industry.","9046655",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1997,"9145261","1,2-Benzisothiazolin-3-one (Proxel): irritant or allergen? A clinical study and literature review.","9145261",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1984,"6241142","[Allergic contact eczema caused by isothiazolin-3-one derivatives].","6241142",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1992,"1395609","Allergic contact dermatitis from the preservative 1,2-benzisothiazolin-3-one (1,2-BIT; Proxel): a case report, its prevalence in those occupationally at risk and in the general dermatological population, and its relationship to allergy to its analogue Kathon CG.","1395609",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1838325","Another isothiazolinone source.","1838325",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1984,"6238787","Allergic contact dermatitis due to 1,2-benzisothiazolin-3-one in gum arabic.","6238787",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1984,"6241142","[Allergic contact eczema caused by isothiazolin-3-one derivatives].","6241142",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1980,"6446435","Contact dermatitis due to benzisothiazolone in a works analytical team.","6446435",40]
["1,2-benzisothiazoline-3-one","1,2-benzisothiazoline-3-one","C015699","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21719283","Benzisothiazolones as modulators of macrophage migration inhibitory factor.","21719283",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C707,B707)","v":"1,2-benzisothiazoline-3-one"},"1,2-benzisothiazoline-3-one","C015699","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J707,K707)","v":"Skin"},"D012867","Skin",0,1,1994,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q707,Q707)","v":"8132178"},"Missed opportunities in clinical dermatology--the case of 1,2-benzisothiazolin-3-one.","8132178",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2001,"11754818","CD40 is a cellular receptor mediating mycobacterial heat shock protein 70 stimulation of CC-chemokines.","11754818",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2004,"14592837","CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2.","14592837",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2000,"11428650","Intervention of sulfur mustard toxicity by downregulation of cell proliferation and metabolic rates.","11428650",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2002,"11920939","Sulfur mustard-stimulated protease: a target for antivesicant drugs.","11920939",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2003,"12839568","Role of intracellular calcium mobilization and cell-density-dependent signaling in oxidative-stress-induced cytotoxicity in HaCaT keratinocytes.","12839568",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2003,"12890758","Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes.","12890758",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2004,"15471881","Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: implications in carcinogenesis.","15471881",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2005,"15713646","Interferon-inducible protein 9 (CXCL11)-induced cell motility in keratinocytes requires calcium flux-dependent activation of mu-calpain.","15713646",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11754818","CD40 is a cellular receptor mediating mycobacterial heat shock protein 70 stimulation of CC-chemokines.","11754818",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"11012878","Stretch activation of jun N-terminal kinase/stress-activated protein kinase in mesangial cells.","11012878",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11707403","Asymmetrical, agonist-induced fluctuations in local extracellular [Ca(2+)] in intact polarized epithelia.","11707403",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12042305","Neurosteroids enhance spontaneous glutamate release in hippocampal neurons. Possible role of metabotropic sigma1-like receptors.","12042305",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15878870","Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.","15878870",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12887973","Vesl/Homer proteins regulate ryanodine receptor type 2 function and intracellular calcium signaling.","12887973",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14622909","Calcium-dependent maintenance of agrin-induced postsynaptic specializations.","14622909",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15226304","Real-time analysis of very late antigen-4 affinity modulation by shear.","15226304",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15591047","Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling.","15591047",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15591144","Corticotropin-releasing hormone-mediated induction of intracellular signaling pathways and brain-derived neurotrophic factor expression is inhibited by the activation of the endocannabinoid system.","15591144",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15657064","The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin.","15657064",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15777838","Contact of Chlamydophila pneumoniae with type II cell triggers activation of calcium-mediated NF-kappa B pathway.","15777838",40]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1996,"8886281","A novel DNA cleaving agent, 2,2'-bis(2-aminoethyl)-4,4'-bithiazole, induces thymocyte apoptosis.","8886281",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1999,"10234008","The ankle-link antigen: an epitope sensitive to calcium chelation associated with the hair-cell surface and the calycal processes of photoreceptors.","10234008",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2003,"12839572","Sequential activation of store-operated currents in human gingival keratinocytes.","12839572",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2003,"12930302","Intracellular calcium pool emptying induces DNA synthesis in HaCaT keratinocytes.","12930302",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2004,"14706838","2-APB inhibits volume-regulated anion channels independently from intracellular calcium signaling modulation.","14706838",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2004,"14980501","Melanin protects melanocytes and keratinocytes against H2O2-induced DNA strand breaks through its ability to bind Ca2+.","14980501",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2001,"11590892","The calcium chelator BAPTA affects the binding of assembly protein AP-2 to membranes.","11590892",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11994289","Basal and physiological Ca(2+) leak from the endoplasmic reticulum of pancreatic acinar cells. Second messenger-activated channels and translocons.","11994289",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12297512","Coordinated signaling through both G12/13 and G(i) pathways is sufficient to activate GPIIb/IIIa in human platelets.","12297512",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2003,"12654309","Isothermal titration calorimetric procedure to determine protein-metal ion binding parameters in the presence of excess metal ion or chelator.","12654309",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14622909","Calcium-dependent maintenance of agrin-induced postsynaptic specializations.","14622909",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14722074","Ca2+ and phosphatidylinositol 4,5-bisphosphate stabilize a Gbeta gamma-sensitive state of Ca V2 Ca 2+ channels.","14722074",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15049708","Generation of singlet oxygen induces phospholipid scrambling in human erythrocytes.","15049708",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15322093","Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1alpha.","15322093",40]
["1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid","C025603","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1996,"8886281","A novel DNA cleaving agent, 2,2'-bis(2-aminoethyl)-4,4'-bithiazole, induces thymocyte apoptosis.","8886281",40]
["1,2-bis(5-hydroxymethyl-2-methyl-3-thienyl)hexafluorocyclopentene","1,2-bis(5-hydroxymethyl-2-methyl-3-thienyl)hexafluorocyclopentene","C586125","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23784945","Enantioselective photochromism of diarylethenes in human serum albumin.","23784945",40]
["1,2-bis(decanoylthio)-1,2-dideoxy-sn-glycerol-3-phosphorylcholine","1,2-bis(decanoylthio)-1,2-dideoxy-sn-glycerol-3-phosphorylcholine","C049380","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3755338","1-Stearyl,2-stearoylaminodeoxy phosphatidylcholine, a potent reversible inhibitor of phospholipase A2.","3755338",40]
["1,2-bis(heptanylcarbamoyl)glycerol 3-sulfate","1,2-bis(heptanylcarbamoyl)glycerol 3-sulfate","C049394","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3718919","Optically detected magnetic resonance studies of porcine pancreatic phospholipase A2 binding to a negatively charged substrate analogue.","3718919",40]
["1,2-bis-N-cytisinylethane","1,2-bis-N-cytisinylethane","C482518","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"22957729","CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation.","22957729",40]
["1,2-cyclohexanediamine","1,2-cyclohexanediamine","C030435","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2001,"11553132","Occupational contact sensitization to 1,2-diaminocyclohexane.","11553132",40]
["1,2-cyclohexanediamine","1,2-cyclohexanediamine","C030435","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2007,"17454030","Review of the toxicology of three alkyl diamines.","17454030",40]
["1,2-cyclohexanediamine","1,2-cyclohexanediamine","C030435","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18595721","Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics.","18595721",40]
["1,2-cyclohexanediamine","1,2-cyclohexanediamine","C030435","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19900814","Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties.","19900814",40]
["1,2-cyclohexanedione","1,2-cyclohexanedione","C018031","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1984,"6325477","Differential effect of arginine modification with 1,2-cyclohexanedione on the capacity of vimentin and desmin to assemble into intermediate filaments and to bind to nucleic acids.","6325477",40]
["1,2-cyclohexanedione","1,2-cyclohexanedione","C018031","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"6444949","Reversible modification of arginine residues in neocarzinostatin. Isolation of a biologically active 89-residue fragment from the tryptic hydrolysate.","6444949",40]
["1,2-cyclohexanedione","1,2-cyclohexanedione","C018031","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"6915938","Location of the intermediate and high affinity omega-aminocarboxylic acid-binding sites in human plasminogen.","6915938",40]
["1,2-cyclohexanedione","1,2-cyclohexanedione","C018031","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7024274","Chemical modifications of Serratia marcescens anthranilate synthase component I.","7024274",40]
["1,2-diacetylbenzene","1,2-diacetylbenzene","C048792","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19404740","New insights into mechanisms of gamma-diketone-induced axonopathy.","19404740",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2005,"16274459","The EP3 receptor stimulates ceramide and diacylglycerol release and inhibits growth of primary keratinocytes.","16274459",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1995,"7832762","Ultraviolet radiation stimulates a biphasic pattern of 1,2-diacylglycerol formation in cultured human melanocytes and keratinocytes by activation of phospholipases C and D.","7832762",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2001,"11352745","Low- and high-affinity phorbol ester and diglyceride interactions with protein kinase C: 1-O-alkyl-2-acyl-sn-glycerol enhances phorbol ester- and diacylglycerol-induced activity but alone does not induce activity.","11352745",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15369389","Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C).","15369389",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15923197","A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms alpha and delta as well as selectivity for RasGRP compared with PKCalpha.","15923197",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18698758","Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities.","18698758",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18707088","Conformationally constrained analogues of diacylglycerol. 30. An investigation of diacylglycerol-lactones containing heteroaryl groups reveals compounds with high selectivity for Ras guanyl nucleotide-releasing proteins.","18707088",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19379015","Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths.","19379015",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"19891956","End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa.","19891956",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23673634","Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol.","23673634",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23874859","Phosphatidylinositol 4,5-bisphosphate decreases the concentration of Ca2+, phosphatidylserine and diacylglycerol required for protein kinase C α to reach maximum activity.","23874859",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25124034","Interfacial partitioning of a loop hinge residue contributes to diacylglycerol affinity of conserved region 1 domains.","25124034",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28154130","Trifunctional lipid probes for comprehensive studies of single lipid species in living cells.","28154130",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1986,"3769135","sn-1,2-Diacylglycerols mimic the effects of 12-O-tetradecanoylphorbol-13-acetate in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis.","3769135",40]
["1,2-diacylglycerol","1,2-diacylglycerol","C011439","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1999,"10358029","Interleukin-2 causes an increase in saturated/monounsaturated phosphatidic acid derived from 1,2-diacylglycerol and 1-O-alkyl-2-acylglycerol.","10358029",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C771,B771)","v":"1,2-diacylglycerol"},"1,2-diacylglycerol","C011439","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J771,K771)","v":"T-Lymphocytes"},"D013601","T-Lymphocytes",1,1,1987,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q771,Q771)","v":"2434339"},"Transmembrane signalling via the T11-dependent pathway of human T cell activation. Evidence for the involvement of 1,2-diacylglycerol and inositol phosphates.","2434339",40]
["1,2-dibenzoyl-tert-butylhydrazine","1,2-dibenzoyl-tert-butylhydrazine","C056565","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11755062","Comparative toxicity and ecdysone receptor affinity of non-steroidal ecdysone agonists and 20-hydroxyecdysone in Chironomus tentans.","11755062",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1999,"10385345","Contact allergy to methyldibromo glutaronitrile presenting as severe scalp seborrhoeic eczema.","10385345",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1999,"10617214","Sensitizing potential in mice, guinea pig and man of the preservative Euxyl K 400 and its ingredient methyldibromo glutaronitrile.","10617214",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"10644036","Increased rate of patch test reactivity to methyldibromo glutaronitrile.","10644036",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"10703625","Provocative use testing of methyldibromo glutaronitrile in a cosmetic shampoo.","10703625",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"10902600","Contact allergy to Euxyl K 400 in consecutively patch-tested patients.","10902600",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"11123412","Patch testing with methyldibromoglutaronitrile.","11123412",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2001,"11156014","Allergic contact dermatitis due to methyldibromo glutaronitrile in Euxyl K 400 in an ultrasonic gel.","11156014",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2001,"11156033","Allergic contact dermatitis due to deer-fat cream (Hirschtalgcreme).","11156033",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"11187213","Improved screening for methyldibromoglutaronitrile allergy.","11187213",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,-1,2001,"11380062","Occupational contact allergy to methyldibromo glutaronitrile in abrasive cleansers and work creams.","11380062",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2002,"12081713","Contact allergy to methyldibromo glutaronitrile in Euxyl K 400 in a cosmetic cream for protection against a permanent wave solution.","12081713",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"12755729","Methyldibromo glutaronitrile: clinical experience and exposure-based risk assessment.","12755729",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"14641369","Increased positive patch test reactivity to methyldibromo glutaronitrile.","14641369",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2004,"14746621","Methyldibromoglutaronitrile in rinse-off products causes allergic contact dermatitis: an experimental study.","14746621",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2004,"15059095","Influence of a detergent on skin response to methyldibromo glutaronitrile in sensitized individuals.","15059095",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2004,"15059109","Post-coital contact dermatitis from methyldibromo glutaronitrile.","15059109",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2004,"15491422","Methyldibromoglutaronitrile in leave-on products elicits contact allergy at low concentration.","15491422",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"15701121","Allergic contact dermatitis from methyldibromo glutaronitrile--clinical cases from 2003.","15701121",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"15701124","Patch testing with methyldibromo glutaronitrile, a multicentre study within the EECDRG.","15701124",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"15701125","Repeated open application test with methyldibromo glutaronitrile, a multicentre study within the EECDRG.","15701125",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"15701126","Recommendation to include methyldibromo glutaronitrile in the European standard patch test series.","15701126",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"15725286","Methyldibromo glutaronitrile contact allergy: effect of single versus repeated daily exposure.","15725286",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"15811027","Contact allergy to methyldibromo glutaronitrile--data from a 'front line' network.","15811027",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"15827583","[Will methyldibromo glutaronitrile (Euxyl K400) be the contact allergen of the year 2005 in Navarra?].","15827583",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"15859992","Quantitative patch and repeated open application testing in methyldibromo glutaronitrile-sensitive patients.","15859992",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"16036118","Allergic contact dermatitis from methyldibromoglutaronitrile.","16036118",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"16364131","Allergic contact dermatitis due to methyldibromo glutaronitrile in make-up removal wipes.","16364131",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2006,"16426287","A clinically relevant contact allergy to methyldibromo glutaronitrile at 1% (0.32 mg/cm) detected by a patch test.","16426287",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2006,"16487288","Connubial allergic contact dermatitis to Euxyl K 400.","16487288",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2006,"16650112","Methyldibromoglutaronitrile contact allergy--the beginning of the end?","16650112",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2007,"17295694","Allergic contact dermatitis from methyldibromo glutaronitrile in a sanitary pad and review of Australian clinic data.","17295694",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2007,"17627659","Occupational allergic contact dermatitis to methyldibromoglutaronitrile in hand degreasing toilet paper.","17627659",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2007,"18021599","Repeated open application tests with methyldibromoglutaronitrile in dermatitis patients with and without hypersensitivity to methyldibromoglutaronitrile.","18021599",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2008,"18537990","Decreasing trends in methyldibromo glutaronitrile contact allergy--following regulatory intervention.","18537990",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2008,"18759875","Proliferative responses in the local lymph node assay associated with concomitant exposure to 1,4-phenylenediamine and methyldibromo glutaronitrile: evidence for synergy?","18759875",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2008,"18795931","Methyldibromoglutaronitrile allergy: relationship between patch test and repeated open application test thresholds.","18795931",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2009,"19457305","[Contact sensitization to Euxyl K-400].","19457305",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2009,"19825091","The dose-response relationship between the patch test and ROAT and the potential use for regulatory purposes.","19825091",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2010,"19883218","Methyldibromoglutaronitrile: skin sensitization and quantitative risk assessment.","19883218",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2010,"20557338","Quantitative repeated open application testing with a rinse-off product in methyldibromo glutaronitrile-sensitive patients: results of the IVDK.","20557338",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2010,"20731688","Ethosome formulation of contact allergens may enhance patch test reactions in patients.","20731688",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2010,"21144344","Patch testing with methyldibromoglutaronitrile in a localized population in the United States.","21144344",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2011,"21317857","Contact hypersensitivity to epoxy resin, methyldibromoglutaronitrile, tixocortol pivalate and budesonide in Hungary: a study in 1448 patients.","21317857",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,-1,2011,"21569742","Allergy to methyldibromoglutaronitrile/phenoxyethanol (Euxyl k 400): regulatory issues, epidemiology, clinical characteristics, and management.","21569742",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2012,"22897782","Undisclosed methyldibromo glutaronitrile causing allergic contact dermatitis in a NSAID cream.","22897782",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,1,2014,"25000241","Conundrums of patch testing to Euxyl K 400 and its components.","25000241",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2017,"28548971","Allergic contact dermatitis in preservatives: current standing and future options.","28548971",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2017,"28885309","Effectiveness of European Regulation on Euxyl K400 Sensitization in Northeastern Italy From 1996 to 2012 and Occupation.","28885309",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"7662570","Increasing incidence of contact allergy to the new preservative 1,2-dibromo-2,4-dicyanobutane (methyldibromoglutaronitrile).","7662570",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1993,"7677800","Frequency of sensitization to Euxyl K 400 in 889 cases.","7677800",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1993,"8112069","Allergic contact dermatitis due to Euxyl K 400 in an ultrasonic gel.","8112069",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1993,"8365190","Contact dermatitis due to dibromodicyanobutane in cucumber eye gel.","8365190",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"8565462","Euxyl K 400: incidence of sensitization, patch test concentration and vehicle.","8565462",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1996,"8681539","Methyldibromoglutaronitrile is an important contact allergen in The Netherlands.","8681539",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1996,"8681555","Contact allergy to methyldibromoglutaronitrile and certain other preservatives.","8681555",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1996,"8807242","How to detect sensitization to Euxyl K 400.","8807242",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1996,"8930497","Occupational allergic contact dermatitis caused by Euxyl K 400.","8930497",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1996,"9007390","Allergic contact dermatitis from Euxyl K 400 in a sunscreen cream.","9007390",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1997,"9066849","Three cases of contact allergy after chemical burns from methylchloroisothiazolinone/methylisothiazolinone: one with concomitant allergy to methyldibromoglutaronitrile/phenoxyethanol.","9066849",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1998,"9632000","Methyldibromoglutaronitrile (Euxyl K400): a new and important sensitizer in the United States?","9632000",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,2010,"21144344","Patch testing with methyldibromoglutaronitrile in a localized population in the United States.","21144344",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1995,"7477511","[Replacement of preservation agent Kathon CG in cosmetics by Euxyl K 400; indeed out of the frying pan into the fire].","7477511",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C835,B835)","v":"1,2-dibromo-2,4-dicyanobutane"},"1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J835,K835)","v":"Dermatitis, Contact"},"D003877","Dermatitis, Contact",0,2,1992,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q835,Q835)","v":"1395613"},"Contact allergy to dibromodicyanobutane in a cosmetic cream.","1395613",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1992,"1552971","[Replacement of Kathon CG by Euxyl K 400 in cosmetics; from the frying pan into the fire?].","1552971",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1799994","Frequency of allergic reactions to methyldibromoglutaronitrile (1,2-dibromo-2,4-dicyanobutane) in The Netherlands.","1799994",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1935042","Frequency of contact sensitization to Euxyl K 400.","1935042",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1935051","Allergic contact dermatitis from Tektamer 38 (dibromocyanobutane).","1935051",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1935053","Euxyl K 400: a new sensitizer in cosmetics.","1935053",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2011,"21317857","Contact hypersensitivity to epoxy resin, methyldibromoglutaronitrile, tixocortol pivalate and budesonide in Hungary: a study in 1448 patients.","21317857",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1989,"2721378","[Contact allergy to a new preservative].","2721378",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"3233965","Sensitization potential of Euxyl K 400.","3233965",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"3349777","Sensitization studies in the guinea pig with the active ingredients of Euxyl K 400.","3349777",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1983,"6226481","Contact dermatitis to a new biocide (Tektamer 38) used in a paste glue formulation.","6226481",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1996,"8912570","Methyldibromoglutaronitrile (Euxyl K 400): an important \"new\" allergen in cosmetics.","8912570",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1997,"9417367","A \"new\" cosmetic allergen.","9417367",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1993,"8112069","Allergic contact dermatitis due to Euxyl K 400 in an ultrasonic gel.","8112069",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1998,"9632000","Methyldibromoglutaronitrile (Euxyl K400): a new and important sensitizer in the United States?","9632000",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,2011,"21317857","Contact hypersensitivity to epoxy resin, methyldibromoglutaronitrile, tixocortol pivalate and budesonide in Hungary: a study in 1448 patients.","21317857",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"18759875","Proliferative responses in the local lymph node assay associated with concomitant exposure to 1,4-phenylenediamine and methyldibromo glutaronitrile: evidence for synergy?","18759875",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"19883218","Methyldibromoglutaronitrile: skin sensitization and quantitative risk assessment.","19883218",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20557338","Quantitative repeated open application testing with a rinse-off product in methyldibromo glutaronitrile-sensitive patients: results of the IVDK.","20557338",40]
["1,2-dibromo-2,4-dicyanobutane","1,2-dibromo-2,4-dicyanobutane","C039411","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20725155","NTP technical report on the toxicology and carcinogenesis studies of 1,2-dibromo-2,4-dicyanobutane (CAS No. 35691-65-7) in F344/N rats and B6C3F1 mice (dermal studies).","20725155",40]
["1,2-dibromo-3-chloropropane","1,2-dibromo-3-chloropropane","C007318","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6373044","Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases and dibromoalkane structure.","6373044",40]
["1,2-dibromo-3-chloropropane","1,2-dibromo-3-chloropropane","C007318","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"8563189","In vitro toxicity of 1,2-dibromo-3-chloropropane (DBCP) in different testicular cell types from rats.","8563189",40]
["1,2-dicaproylphosphatidylserine","1,2-dicaproylphosphatidylserine","C402786","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15641797","The phosphatidylserine binding site of the factor Va C2 domain accounts for membrane binding but does not contribute to the assembly or activity of a human factor Xa-factor Va complex.","15641797",40]
["1,2-dichloro-4-nitrobenzene","1,2-dichloro-4-nitrobenzene","C028328","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1996,"8789227","Dichloronitrobenzene: a reappraisal of its skin sensitization potential.","8789227",40]
["1,2-didecanemethylenebis(4-methyl-5-ethylthiazolium)","1,2-didecanemethylenebis(4-methyl-5-ethylthiazolium)","C477299","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12878523","Heme binding contributes to antimalarial activity of bis-quaternary ammoniums.","12878523",40]
["1,2-didecanoylglycerol","1,2-didecanoylglycerol","C044297","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7545008","Interfacial binding of human gastric lipase to lipid monolayers, measured with an ELISA.","7545008",40]
["1,2-didecanoylglycerol","1,2-didecanoylglycerol","C044297","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2743335","Synthetic lipid second messenger sn-1,2-didecanoylglycerol: a complete tumor promoter in mouse skin.","2743335",40]
["1,2-didecanoylglycerol","1,2-didecanoylglycerol","C044297","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1988,"3191567","sn-1,2-didecanoylglycerol effectively induces epidermal ornithine decarboxylase but only weak hyperplasia in mouse skin.","3191567",40]
["1,2-didecanoylglycerol","1,2-didecanoylglycerol","C044297","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1988,"3191568","Comparison of the effect of sn-1,2-didecanoylglycerol and 12-O-tetradecanoylphorbol-13-acetate on cutaneous morphology, inflammation and tumor promotion in CD-1 mice.","3191568",40]
["1,2-didecanoylphosphatidylcholine","1,2-didecanoylphosphatidylcholine","C015132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6882757","Studies on the complex formed between glucagon and dicaprylphosphatidylcholine.","6882757",40]
["1,2-didecanoylphosphatidylcholine","1,2-didecanoylphosphatidylcholine","C015132","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1997,"9178620","Interference of a short-chain phospholipid with ion transport pathways in frog skin.","9178620",40]
["1,2-didodecanoyl-glycero-3-phosphocholine","1,2-didodecanoyl-glycero-3-phosphocholine","C054349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2730878","Interactions of colicin A domains with phospholipid monolayers and liposomes: relevance to the mechanism of action.","2730878",40]
["1,2-dielaidoylphosphatidylethanolamine","1,2-dielaidoylphosphatidylethanolamine","C020888","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2001,"11479025","Effects of lipofectin-antigen complexes on major histocompatibility complex class I-restricted antigen presentation pathway in murine dendritic cells and on dendritic cell maturation.","11479025",40]
["1,2-dielaidoylphosphatidylethanolamine","1,2-dielaidoylphosphatidylethanolamine","C020888","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"21048315","A phagocytotic inducer from herbal constituent, pentagalloylglucose enhances lipoplex-mediated gene transfection in dendritic cells.","21048315",40]
["1,2-dielaidoylphosphatidylethanolamine","1,2-dielaidoylphosphatidylethanolamine","C020888","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"11199267","Serum as a modulator of lipoplex-mediated gene transfection: dependence of amphiphile, cell type and complex stability.","11199267",40]
["1,2-dielaidoylphosphatidylethanolamine","1,2-dielaidoylphosphatidylethanolamine","C020888","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2819088","The role of protein-linked oligosaccharide in the bilayer stabilization activity of glycophorin A for dioleoylphosphatidylethanolamine liposomes.","2819088",40]
["1,2-dielaidoylphosphatidylethanolamine","1,2-dielaidoylphosphatidylethanolamine","C020888","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6307366","Cooperative lipid activation of (Na+ + K+)-ATPASE as a consequence of non-cooperative lipid-protein interactions.","6307366",40]
["1,2-diethyl-3-hydroxypyridin-4-one","1,2-diethyl-3-hydroxypyridin-4-one","C068543","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2007,"17576385","Direct comparison of delta-aminolevulinic acid and methyl-aminolevulinate-derived protoporphyrin IX accumulations potentiated by desferrioxamine or the novel hydroxypyridinone iron chelator CP94 in cultured human cells.","17576385",40]
["1,2-diglycidyl phthalate","1,2-diglycidyl phthalate","C042839","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1984,"6237880","Contact dermatitis from the epoxy resins tetraglycidyl-4,4'-methylene dianiline and o-diglycidyl phthalate in composite material.","6237880",40]
["1,2-dihexadecyl-sn-glycero-3-phosphocholine","1,2-dihexadecyl-sn-glycero-3-phosphocholine","C052298","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21901295","Structure of a protein-detergent complex: the balance between detergent cohesion and binding.","21901295",40]
["1,2-dihexadecyl-sn-glycero-3-phosphocholine","1,2-dihexadecyl-sn-glycero-3-phosphocholine","C052298","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24218049","Solution NMR analysis of the interaction between the actinoporin sticholysin I and DHPC micelles--correlation with backbone dynamics.","24218049",40]
["1,2-dihexadecyl-sn-glycero-3-phosphocholine","1,2-dihexadecyl-sn-glycero-3-phosphocholine","C052298","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"18053662","Effect of bicellar systems on skin properties.","18053662",40]
["1,2-dihexadecyl-sn-glycero-3-phosphocholine","1,2-dihexadecyl-sn-glycero-3-phosphocholine","C052298","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23269481","Characterization of new DOPC/DHPC platform for dermal applications.","23269481",40]
["1,2-dihexanoyl-sn-glycero-3-phosphorylcholine","1,2-dihexanoyl-sn-glycero-3-phosphorylcholine","C092445","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12719256","Allosteric interactions within subsites of a monomeric enzyme: kinetics of fluorogenic substrates of PI-specific phospholipase C.","12719256",40]
["1,2-dihydro-2,2,4-trimethylquinoline","1,2-dihydro-2,2,4-trimethylquinoline","C053059","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10215184","Carcinogenicity of dermally administered 1,2-dihydro-2,2,4-trimethylquinoline monomer in F344 rats and B6C3F1 mice.","10215184",40]
["1',2'-dihydrorotenone","1',2'-dihydrorotenone","C044985","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3297786","Photolabelling of a mitochondrially encoded subunit of NADH dehydrogenase with [3H]dihydrorotenone.","3297786",40]
["1',2'-dihydrorotenone","1',2'-dihydrorotenone","C044985","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9119899","Intrastriatal neurotoxin injections reduce in vitro and in vivo binding of radiolabeled rotenoids to mitochondrial complex I.","9119899",40]
["1,2-dihydroxy-5,6-dimethyl-3,4-epoxy-1,2,3,4-tetrahydrochrysene","1,2-dihydroxy-5,6-dimethyl-3,4-epoxy-1,2,3,4-tetrahydrochrysene","C075956","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9472707","Comparative mouse skin tumorigenicity and induction of Ha-ras mutations by bay region diol epoxides of 5-methylchrysene and 5,6-dimethylchrysene.","9472707",40]
["1,2-dihydroxy-epoxy-1,2,3,4-tetrahydro-5-methylchrysene","1,2-dihydroxy-epoxy-1,2,3,4-tetrahydro-5-methylchrysene","C037783","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9472707","Comparative mouse skin tumorigenicity and induction of Ha-ras mutations by bay region diol epoxides of 5-methylchrysene and 5,6-dimethylchrysene.","9472707",40]
["1,2-dihydroxynaphthalene","1,2-dihydroxynaphthalene","C050642","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28728845","Crystal structure of cis-dihydrodiol naphthalene dehydrogenase (NahB) from Pseudomonas sp. MC1: Insights into the early binding process of the substrate.","28728845",40]
["1,2-dilauroylphosphatidylcholine","1,2-dilauroylphosphatidylcholine","C015153","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10644712","Engineering microsomal cytochrome P450 2C5 to be a soluble, monomeric enzyme. Mutations that alter aggregation, phospholipid dependence of catalysis, and membrane binding.","10644712",40]
["1,2-dilauroylphosphatidylcholine","1,2-dilauroylphosphatidylcholine","C015153","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21614002","A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects.","21614002",40]
["1,2-dilauroylphosphatidylcholine","1,2-dilauroylphosphatidylcholine","C015153","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22075563","Probing the oligomeric state and interaction surfaces of Fukutin-I in dilauroylphosphatidylcholine bilayers.","22075563",40]
["1,2-dilauroylphosphatidylcholine","1,2-dilauroylphosphatidylcholine","C015153","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22504882","Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation.","22504882",40]
["1,2-dilauroylphosphatidylcholine","1,2-dilauroylphosphatidylcholine","C015153","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23838197","New insights into the pH-dependent interfacial adsorption of dog gastric lipase using the monolayer technique.","23838197",40]
["1,2-dilauroylphosphatidylethanolamine","1,2-dilauroylphosphatidylethanolamine","C007445","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8262901","Molecular dynamics simulation of 1,2-dilauroyl-L-phosphatidylethanolamine binding to phospholipase A2: an attempt to explain the selective hydrolysis of substrate fatty acid ester at position 2.","8262901",40]
["1,2-Dimethylhydrazine","1,2-Dimethylhydrazine","D019813","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2012,"22420317","Dietary mustard seeds (Sinapis alba Linn) suppress 1,2-dimethylhydrazine-induced immuno-imbalance and colonic carcinogenesis in rats.","22420317",40]
["1,2-Dimethylhydrazine","1,2-Dimethylhydrazine","D019813","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2012,"22420317","Dietary mustard seeds (Sinapis alba Linn) suppress 1,2-dimethylhydrazine-induced immuno-imbalance and colonic carcinogenesis in rats.","22420317",40]
["1,2-Dimethylhydrazine","1,2-Dimethylhydrazine","D019813","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2000,"10769684","Response of the spleen of Balb/c and p53-transgenic mice to low doses of carcinogen and to polyclonal antibodies generated against the soluble 53 kDa protein.","10769684",40]
["1,2-Dimethylhydrazine","1,2-Dimethylhydrazine","D019813","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2012,"22420317","Dietary mustard seeds (Sinapis alba Linn) suppress 1,2-dimethylhydrazine-induced immuno-imbalance and colonic carcinogenesis in rats.","22420317",40]
["1,2-Dimethylhydrazine","1,2-Dimethylhydrazine","D019813","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23514809","Role of cytokines and Jak3/Stat3 signaling in the 1,2-dimethylhydrazine dihydrochloride-induced rat model of colon carcinogenesis: early target in the anticancer strategy.","23514809",40]
["1,2-Dimethylhydrazine","1,2-Dimethylhydrazine","D019813","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"6796253","Parameters for detection of mutagenesis of 1,2-dimethylhydrazine using an in vitro Bacillus subtilis system.","6796253",40]
["1,2-Dimethylhydrazine","1,2-Dimethylhydrazine","D019813","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7718806","[Comparative characteristics of specific binding of estradiol-17beta with proteins-receptors in CBA and C57Bl/6 murine line uterine cytosol during sarcomagenesis induced by 1,2-dimethylhydrazine].","7718806",40]
["1,2-Dimethylhydrazine","1,2-Dimethylhydrazine","D019813","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"3871659","Comparison of immune status and 1,2-dimethylhydrazine induced tumorigenesis in brown--Norway and Fischer rats. Emphasis on splenic and colonic lymphocyte function.","3871659",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C899,B899)","v":"1,2-dimyristoylphosphatidylethanolamine"},"1,2-dimyristoylphosphatidylethanolamine","C018525","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J899,K899)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2004,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q899,Q899)","v":"15204438"},"Membrane interaction of erythroid spectrin: surface-density-dependent high-affinity binding to phosphatidylethanolamine.","15204438",40]
["1,2-dimyristoylphosphatidylethanolamine","1,2-dimyristoylphosphatidylethanolamine","C018525","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22538355","Gly(6) of kalata B1 is critical for the selective binding to phosphatidylethanolamine membranes.","22538355",40]
["1,2-dimyristoylphosphatidylethanolamine","1,2-dimyristoylphosphatidylethanolamine","C018525","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25011632","Assembly and stability of Salmonella enterica ser. Typhi TolC protein in POPE and DMPE.","25011632",40]
["1,2-dimyristoylphosphatidylethanolamine","1,2-dimyristoylphosphatidylethanolamine","C018525","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26184723","Fluorescence study of the effect of cholesterol on spectrin-aminophospholipid interactions.","26184723",40]
["1,2-dimyristoylphosphatidylethanolamine","1,2-dimyristoylphosphatidylethanolamine","C018525","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3607004","Electrostatic coupling of spectrin dimers to phosphatidylserine containing lipid lamellae.","3607004",40]
["1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine","1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine","C108836","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26071843","PIP2 and PIP3 interact with N-terminus region of TRPM4 channel.","26071843",40]
["1,2-dioctanoylglycerol","1,2-dioctanoylglycerol","C044295","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1756112","Diacylglycerol-induced melanogenesis in Skh-2 pigmented hairless mice.","1756112",40]
["1,2-dioctanoylglycerol","1,2-dioctanoylglycerol","C044295","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2706740","Comparison of epidermal protein kinase C activity, ornithine decarboxylase induction and DNA synthesis stimulated by TPA or dioctanoylglycerol in mouse strains with differing susceptibility to TPA-induced tumor promotion.","2706740",40]
["1,2-dioctanoylglycerol","1,2-dioctanoylglycerol","C044295","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2743335","Synthetic lipid second messenger sn-1,2-didecanoylglycerol: a complete tumor promoter in mouse skin.","2743335",40]
["1,2-dioctanoylglycerol","1,2-dioctanoylglycerol","C044295","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1987,"3498045","Diacylglycerols stimulate short-circuit current across frog skin by increasing apical Na+ permeability.","3498045",40]
["1,2-dioctanoylglycerol","1,2-dioctanoylglycerol","C044295","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1991,"1872854","Lysophosphatidylcholine as a possible second messenger synergistic to diacylglycerol and calcium ion for T-lymphocyte activation.","1872854",40]
["1,2-dioctanoylglycerol","1,2-dioctanoylglycerol","C044295","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1989,"2785492","Inhibition of the CD3-mediated calcium signal by protein kinase C activators in human T (Jurkat) lymphoblastoid cells.","2785492",40]
["1,2-dioctanoylglycerol","1,2-dioctanoylglycerol","C044295","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1989,"2786413","The diacylglycerol analogue, 1,2-sn-dioctanoylglycerol, induces an increase in cytosolic free Ca2+ and cytosolic acidification of T lymphocytes through a protein kinase C-independent process.","2786413",40]
["1,2-dioctanoylglycerol","1,2-dioctanoylglycerol","C044295","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1988,"2902930","Activation of human T cells with the physiological regulator of protein kinase C.","2902930",40]
["1,2-dioleoyl-3-succinylglycerol","1,2-dioleoyl-3-succinylglycerol","C088169","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16308208","Generation of immunoliposomes using recombinant single-chain Fv fragments bound to Ni-NTA-liposomes.","16308208",40]
["1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"11199267","Serum as a modulator of lipoplex-mediated gene transfection: dependence of amphiphile, cell type and complex stability.","11199267",40]
["1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11361005","Isothermal titration calorimetric analysis of the interaction between cationic lipids and plasmid DNA.","11361005",40]
["1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11508840","The mechanism of the stabilization of the hexagonal II (HII) phase in phosphatidylethanolamine membranes in the presence of low concentrations of dimethyl sulfoxide.","11508840",40]
["1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11583168","Effect of nonbilayer lipids on membrane binding and insertion of the catalytic domain of leader peptidase.","11583168",40]
["1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11583999","Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery.","11583999",40]
["1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15501933","Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy.","15501933",40]
["1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15544347","Lipid modulation of the activity of diacylglycerol kinase alpha- and zeta-isoforms: activation by phosphatidylethanolamine and cholesterol.","15544347",40]
["1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17704174","Interaction of an amphipathic peptide with phosphatidycholine/phosphatidylethanolamine mixed membranes.","17704174",40]
["1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"19961210","Study on the interaction of cationic lipids with bovine serum albumin.","19961210",40]
["1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26184723","Fluorescence study of the effect of cholesterol on spectrin-aminophospholipid interactions.","26184723",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,1992,"1518813","Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway.","1518813",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2012,"22226776","PEGylated cationic liposomes robustly augment vaccine-induced immune responses: Role of lymphatic trafficking and biodistribution.","22226776",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2015,"26714419","Cationic Immune Stimulating Complexes Containing Soluble Leishmania Antigens: Preparation, Characterization and in Vivo Immune Response Evaluation.","26714419",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2009,"19503805","Efficient siRNA delivery by the cationic liposome DOTAP in human hematopoietic stem cells differentiating into dendritic cells.","19503805",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2011,"21267720","Enantiospecific adjuvant activity of cationic lipid DOTAP in cancer vaccine.","21267720",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2012,"22226776","PEGylated cationic liposomes robustly augment vaccine-induced immune responses: Role of lymphatic trafficking and biodistribution.","22226776",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2016,"27412723","An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept.","27412723",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2017,"28866132","Combining R-DOTAP and a particulate antigen delivery platform to trigger dendritic cell activation: Formulation development and in-vitro interaction studies.","28866132",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16149907","Reversible mode of binding of serum proteins to DOTAP/cholesterol Lipoplexes: a possible explanation for intravenous lipofection efficiency.","16149907",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"19961210","Study on the interaction of cationic lipids with bovine serum albumin.","19961210",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21542594","Binding of cationic lipids to milk β-lactoglobulin.","21542594",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2017,"28762497","T cell-dependent antigen adjuvanted with DOTAP-CpG-B but not DOTAP-CpG-A induces robust germinal center responses and high affinity antibodies in mice.","28762497",40]
["1,2-dioleoyloxy-3-(trimethylammonium)propane","1,2-dioleoyloxy-3-(trimethylammonium)propane","C070046","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1993,"8267621","Cationic lipids improve antisense oligonucleotide uptake and prevent degradation in cultured cells and in human serum.","8267621",40]
["1,2-dioleoylphosphatidylinositol 4,5-bisphosphate","1,2-dioleoylphosphatidylinositol 4,5-bisphosphate","C532047","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22538354","Effect of phosphorylation of phosphatidylinositol on myelin basic protein-mediated binding of actin filaments to lipid bilayers in vitro.","22538354",40]
["1,2-dioleoylphosphatidylserine","1,2-dioleoylphosphatidylserine","C042511","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11444970","Soluble phosphatidylserine binds to a single identified site in the C2 domain of human factor Va.","11444970",40]
["1,2-dioleoylphosphatidylserine","1,2-dioleoylphosphatidylserine","C042511","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22229667","The importance of an asymmetric distribution of acidic lipids for synaptotagmin 1 function as a Ca2+ sensor.","22229667",40]
["1,2-dioleoylphosphatidylserine","1,2-dioleoylphosphatidylserine","C042511","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23643891","Insertion of TAT peptide and perturbation of negatively charged model phospholipid bilayer revealed by neutron diffraction.","23643891",40]
["1,2-dioleoylphosphatidylserine","1,2-dioleoylphosphatidylserine","C042511","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27160923","Detection of cancer cells using SapC-DOPS nanovesicles.","27160923",40]
["1,2-dioleoylphosphatidylserine","1,2-dioleoylphosphatidylserine","C042511","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6466619","Interaction of prothrombin with factor Va-phospholipid complexes.","6466619",40]
["1,2-dioleoylphosphatidylserine","1,2-dioleoylphosphatidylserine","C042511","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7577961","Inhibition of prothrombinase at macroscopic lipid membranes: competition between antithrombin and prothrombin.","7577961",40]
["1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine-N-(N-(5-amino-1-carboxypentyl(iminodiacetic acid)succinimide))","1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine-N-(N-(5-amino-1-carboxypentyl(iminodiacetic acid)succinimide))","C093198","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11210529","Expression, purification, and characterization of Rab5 effector complex, rabaptin-5/rabex-5.","11210529",40]
["1,2-dioleoyl-sn-glycero-3-phosphoglycerol","1,2-dioleoyl-sn-glycero-3-phosphoglycerol","C051388","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15321714","Phospholipid catalysis of diabetic amyloid assembly.","15321714",40]
["1,2-dioleoyl-sn-glycero-3-phosphoglycerol","1,2-dioleoyl-sn-glycero-3-phosphoglycerol","C051388","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15347587","Cytochrome c adsorption to supported, anionic lipid bilayers studied via atomic force microscopy.","15347587",40]
["1,2-dioleoyl-sn-glycero-3-phosphoglycerol","1,2-dioleoyl-sn-glycero-3-phosphoglycerol","C051388","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25909158","Oligomers of Parkinson's Disease-Related α-Synuclein Mutants Have Similar Structures but Distinctive Membrane Permeabilization Properties.","25909158",40]
["1,2-dioleoyl-sn-glycero-3-phosphoglycerol","1,2-dioleoyl-sn-glycero-3-phosphoglycerol","C051388","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25445669","The role of tryptophans on the cellular uptake and membrane interaction of arginine-rich cell penetrating peptides.","25445669",40]
["1,2-dioleoyl-sn-glycero-3-phosphoglycerol","1,2-dioleoyl-sn-glycero-3-phosphoglycerol","C051388","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27240304","Reduced and mutant lysozyme refolding with lipid vesicles. Model study of disulfide impact on equilibria and dynamics.","27240304",40]
["1,2-dioleoyl-sn-glycero-3-phosphoglycerol","1,2-dioleoyl-sn-glycero-3-phosphoglycerol","C051388","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27806910","Structure and function of PspA and Vipp1 N-terminal peptides: Insights into the membrane stress sensing and mitigation.","27806910",40]
["1,2-dioleoyl-sn-glycero-3-phosphoglycerol","1,2-dioleoyl-sn-glycero-3-phosphoglycerol","C051388","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7696507","Protein surface-distribution and protein-protein interactions in the binding of peripheral proteins to charged lipid membranes.","7696507",40]
["1,2-dioleoyl-sn-glycero-3-phosphoglycerol","1,2-dioleoyl-sn-glycero-3-phosphoglycerol","C051388","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8672424","Partitioning of HIV-1 Gag and Gag-related proteins to membranes.","8672424",40]
["1,2-dioleoyl-sn-glycero-3-phosphoglycerol","1,2-dioleoyl-sn-glycero-3-phosphoglycerol","C051388","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9692963","FTIR study of the thermal denaturation of alpha-actinin in its lipid-free and dioleoylphosphatidylglycerol-bound states and the central and N-terminal domains of alpha-actinin in D2O.","9692963",40]
["1,2-dipalmitoyl-3-phosphatidylethanolamine","1,2-dipalmitoyl-3-phosphatidylethanolamine","C007510","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,2014,"24597467","Use of thermodynamic coupling between antibody-antigen binding and phospholipid acyl chain phase transition energetics to predict immunoliposome targeting affinity.","24597467",40]
["1,2-dipalmitoyl-3-phosphatidylethanolamine","1,2-dipalmitoyl-3-phosphatidylethanolamine","C007510","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2013,"23535021","Effective stimulation of invariant natural killer T cells by oligomannose-coated liposomes.","23535021",40]
["1,2-dipalmitoyl-3-phosphatidylethanolamine","1,2-dipalmitoyl-3-phosphatidylethanolamine","C007510","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2015,"25673047","Anchoring dipalmitoyl phosphoethanolamine to nanoparticles boosts cellular uptake and fluorine-19 magnetic resonance signal.","25673047",40]
["1,2-dipalmitoyl-3-phosphatidylethanolamine","1,2-dipalmitoyl-3-phosphatidylethanolamine","C007510","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11508840","The mechanism of the stabilization of the hexagonal II (HII) phase in phosphatidylethanolamine membranes in the presence of low concentrations of dimethyl sulfoxide.","11508840",40]
["1,2-dipalmitoyl-3-phosphatidylethanolamine","1,2-dipalmitoyl-3-phosphatidylethanolamine","C007510","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18389231","Spectroscopic and calorimetric studies on the interaction of human serum albumin with DPPC/PEG:2000-DPPE membranes.","18389231",40]
["1,2-dipalmitoyl-3-phosphatidylethanolamine","1,2-dipalmitoyl-3-phosphatidylethanolamine","C007510","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3348808","Binding of C3 molecules to membranes via the SH-residue generated by the cleavage of a thioester bond can initiate complement activation.","3348808",40]
["1,2-dipalmitoyl-3-phosphatidylethanolamine","1,2-dipalmitoyl-3-phosphatidylethanolamine","C007510","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1997,"9218554","Grafted poly-(ethylene glycol) on lipid surfaces inhibits protein adsorption and cell adhesion.","9218554",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1998,"9623764","The interaction of phospholipase A2 with liposomes: an immunological approach to its study.","9623764",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11687229","Association of acylated cationic decapeptides with dipalmitoylphosphatidylserine-dipalmitoylphosphatidylcholine lipid membranes.","11687229",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C963,B963)","v":"1,2-Dipalmitoylphosphatidylcholine"},"1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J963,K963)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2002,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q963,Q963)","v":"12460572"},"Molecular dynamics simulations on discoidal HDL particles suggest a mechanism for rotation in the apo A-I belt model.","12460572",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14507703","Interaction of pulmonary surfactant protein SP-A with DPPC/egg-PG bilayers.","14507703",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14507728","Aggregation of puroindoline in phospholipid monolayers spread at the air-liquid interface.","14507728",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12829482","Ion channels of alamethicin dimer N-terminally linked by disulfide bond.","12829482",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14645043","Permeation across hydrated DPPC lipid bilayers: simulation of the titrable amphiphilic drug valproic acid.","14645043",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14695273","Distribution of GD3 in DPPC monolayers: a thermodynamic and atomic force microscopy combined study.","14695273",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14997358","Binding of chimeric metal-binding green fluorescent protein to lipid monolayer.","14997358",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15240466","AFM visualization of mobile influenza A M2 molecules in planar bilayers.","15240466",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15339796","Dynamic structure of vesicle-bound melittin in a variety of lipid chain lengths by solid-state NMR.","15339796",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15738465","Molecular dynamics study of the lung surfactant peptide SP-B1-25 with DPPC monolayers: insights into interactions and peptide position and orientation.","15738465",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15979580","GPI-alkaline phosphatase insertion into phosphatidylcholine monolayers: phase behavior and morphology changes.","15979580",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16040748","Interaction of the antimicrobial peptide cyclo(RRWWRF) with membranes by molecular dynamics simulations.","16040748",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16150829","Interaction of a partially fluorinated long-chain nicotinate with dipalmitoylphosphatidylcholine.","16150829",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16278220","Model of biologically active apolipoprotein E bound to dipalmitoylphosphatidylcholine.","16278220",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16632503","Lipid specificity of surfactant protein B studied by time-of-flight secondary ion mass spectrometry.","16632503",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17583923","Protein-directed assembly of binary monolayers at the interface and surface patterns of protein on the monolayers.","17583923",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16997879","In situ scanning probe microscopy studies of tetanus toxin-membrane interactions.","16997879",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17186235","Membrane binding of a lipidated N-Ras protein studied in lipid monolayers.","17186235",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17434940","Comparison of DPPC and DPPG environments in pulmonary surfactant models.","17434940",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17693477","Surfactant protein A forms extensive lattice-like structures on 1,2-dipalmitoylphosphatidylcholine/rough-lipopolysaccharide-mixed monolayers.","17693477",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18389231","Spectroscopic and calorimetric studies on the interaction of human serum albumin with DPPC/PEG:2000-DPPE membranes.","18389231",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1998703","Size and stability of dipalmitoylphosphatidylcholine/cholesterol unilamellar vesicles are affected by interaction with proteins.","1998703",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22148887","Slow insertion kinetics during interaction of a model antimicrobial peptide with unilamellar phospholipid vesicles.","22148887",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22300899","Zwitterionic lipid (DPPC)-protein (BSA) complexes at the air-water interface.","22300899",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23031572","Thermotropic and structural effects of poly(malic acid) on fully hydrated multilamellar DPPC-water systems.","23031572",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23499547","Early stages of interactions of cell-penetrating peptide penetratin with a DPPC bilayer.","23499547",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24668218","Surface tension effects on the phase transition of a DPPC bilayer with and without protein: a molecular dynamics simulation.","24668218",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24987931","Integration of surface-active, periodically sequenced peptides into lipid-based microbubbles.","24987931",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27742354","Polyunsaturated chains in asymmetric lipids disorder raft mixtures and preferentially associate with α-Synuclein.","27742354",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28130642","Interaction of aurein 1.2 and its analogue with DPPC lipid bilayer.","28130642",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2818591","A region-matched hydrophobic interaction between melittin and dimyristoylphosphatidylcholine in a ternary mixture of phosphatidylcholines.","2818591",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28407364","Identification of a conserved 8 aa insert in the PIP5K protein in the Saccharomycetaceae family of fungi and the molecular dynamics simulations and structural analysis to investigate its potential functional role.","28407364",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28695731","Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes.","28695731",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3396853","Interactions of calcium binding proteins, parvalbumin and alpha-lactalbumin, with dipalmitoylphosphatidylcholine vesicles.","3396853",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3559547","Spectroscopic studies on Zn(II)-phthalocyanine in homogeneous and microheterogeneous systems.","3559547",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7306517","Interaction of rhodopsin with two unsaturated phosphatidylcholines: a deuterium nuclear magnetic resonance study.","7306517",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8573110","Comparison of lipid aggregation and self-aggregation activities of pulmonary surfactant-associated protein A.","8573110",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8634309","Effect of serum protein binding on real-time trafficking of liposomes with different charges analyzed by positron emission tomography.","8634309",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"9172743","Influence of lipid chain unsaturation on melittin-induced micellization.","9172743",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9199811","Structure and orientation of lung surfactant SP-C and L-alpha-dipalmitoylphosphatidylcholine in aqueous monolayers.","9199811",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9692961","Definition of the specific roles of lysolecithin and palmitic acid in altering the susceptibility of dipalmitoylphosphatidylcholine bilayers to phospholipase A2.","9692961",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9813343","Regulatory mechanisms of surfactant secretion.","9813343",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2002,"12377605","Experimental study of podophyllotoxin dipalmitoylphosphatidylcholine liposome for topical skin application.","12377605",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2009,"19432456","Lipid nanostructures: self-assembly and effect on skin properties.","19432456",40]
["1,2-Dipalmitoylphosphatidylcholine","1,2-Dipalmitoylphosphatidylcholine","D015060","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21319163","Decrease of liposomal size and retarding effect on fluconazole skin permeation by lysine derivatives.","21319163",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14507728","Aggregation of puroindoline in phospholipid monolayers spread at the air-liquid interface.","14507728",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15498759","Surfactant protein A binds Mycoplasma pneumoniae with high affinity and attenuates its growth by recognition of disaturated phosphatidylglycerols.","15498759",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15584897","Interaction of three-finger toxins with phospholipid membranes: comparison of S- and P-type cytotoxins.","15584897",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16632503","Lipid specificity of surfactant protein B studied by time-of-flight secondary ion mass spectrometry.","16632503",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17434940","Comparison of DPPC and DPPG environments in pulmonary surfactant models.","17434940",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"19053706","Interfacial structure of wild-type and mutant forms of puroindoline-b bound to DPPG monolayers.","19053706",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21869972","Lipid binding interactions of antimicrobial plant seed defence proteins: puroindoline-a and β-purothionin.","21869972",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26903220","Binding of cationic peptides (KX)4K to DPPG bilayers. Increasing the hydrophobicity of the uncharged amino acid X drives formation of membrane bound β-sheets: A DSC and FT-IR study.","26903220",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"6171298","Interaction of myelin basic protein with dipalmitoylphosphatidylglycerol: dependence on the lipid phase and investigation of a metastable state.","6171298",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6201246","Comparison of metastable phase behavior of the complexes of dipalmitoyl phosphatidylglycerol with Mg+2 and myelin basic protein.","6201246",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8573110","Comparison of lipid aggregation and self-aggregation activities of pulmonary surfactant-associated protein A.","8573110",40]
["1,2-dipalmitoylphosphatidylglycerol","1,2-dipalmitoylphosphatidylglycerol","C030345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9062115","Interactions of thionin from Pyrularia pubera with dipalmitoylphosphatidylglycerol large unilamellar vesicles.","9062115",40]
["1,2-distearoyllecithin","1,2-distearoyllecithin","C010942","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"21283989","Preparation, characterisation and entrapment of a non-glycosidic threitol ceramide into liposomes for presentation to invariant natural killer T cells.","21283989",40]
["1,2-distearoyllecithin","1,2-distearoyllecithin","C010942","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2818591","A region-matched hydrophobic interaction between melittin and dimyristoylphosphatidylcholine in a ternary mixture of phosphatidylcholines.","2818591",40]
["1,2-distearoyllecithin","1,2-distearoyllecithin","C010942","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3167002","Synthetic branched-chain analogues of distearoylphosphatidylcholine: structure-activity relationship in inhibiting and activating protein kinase C.","3167002",40]
["1,2-distearoyllecithin","1,2-distearoyllecithin","C010942","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"7104334","Melittin-phospholipid interaction studied by employing the single tryptophan residue as an intrinsic fluorescent probe.","7104334",40]
["1,2-distearoyllecithin","1,2-distearoyllecithin","C010942","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8889162","Reversible adsorption and nonreversible insertion of Escherichia coli alpha-hemolysin into lipid bilayers.","8889162",40]
["1,2-distearoylphosphatidylethanolamine","1,2-distearoylphosphatidylethanolamine","C038089","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,3,2017,"28516182","Intracellular accumulation and immunological responses of lipid modified magnetic iron nanoparticles in mouse antigen processing cells.","28516182",40]
["1,2-distearoylphosphatidylethanolamine","1,2-distearoylphosphatidylethanolamine","C038089","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2012,"22229467","Effective targeted gene delivery to dendritic cells via synergetic interaction of mannosylated lipid with DOPE and BCAT.","22229467",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1027,B1027)","v":"1,2-distearoylphosphatidylethanolamine"},"1,2-distearoylphosphatidylethanolamine","C038089","2_KE",826,2,"Keratinocytes","Activation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1027,K1027)","v":"Keratinocytes"},"D015603","Keratinocytes",1,3,2007,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1027,Q1027)","v":"17344000"},"Biocompatible, biodegradable and sterically stabilized phospholipid nanomicelles improve cryopreservation of oral keratinocytes: a preliminary investigation.","17344000",40]
["1,2-distearoylphosphatidylethanolamine","1,2-distearoylphosphatidylethanolamine","C038089","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17400180","Influence of poly(ethylene glycol) grafting density and polymer length on liposomes: relating plasma circulation lifetimes to protein binding.","17400180",40]
["1,2-distearoylphosphatidylethanolamine","1,2-distearoylphosphatidylethanolamine","C038089","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1997,"9218554","Grafted poly-(ethylene glycol) on lipid surfaces inhibits protein adsorption and cell adhesion.","9218554",40]
["1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)","1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)","C519184","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2012,"22226776","PEGylated cationic liposomes robustly augment vaccine-induced immune responses: Role of lymphatic trafficking and biodistribution.","22226776",40]
["1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)","1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)","C519184","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2012,"22226776","PEGylated cationic liposomes robustly augment vaccine-induced immune responses: Role of lymphatic trafficking and biodistribution.","22226776",40]
["1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)","1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)","C519184","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16762454","PEGylated phospholipid nanomicelles interact with beta-amyloid((1-42)) and mitigate its beta-sheet formation, aggregation and neurotoxicity in vitro.","16762454",40]
["1,2-ditetradecylphosphatidylcholine","1,2-ditetradecylphosphatidylcholine","C047037","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"4052389","Interaction of lipoprotein lipase and apolipoprotein C-II with sonicated vesicles of 1,2-ditetradecylphosphatidylcholine: comparison of binding constants.","4052389",40]
["1,2-dithiol-3-thione","1,2-dithiol-3-thione","C049325","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2016,"27013356","3H-1,2-dithiole-3-thione as a novel therapeutic agent for the treatment of experimental autoimmune encephalomyelitis.","27013356",40]
["1,2-dithiol-3-thione","1,2-dithiol-3-thione","C049325","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2007,"17854798","Induction of Nrf2-regulated genes by 3H-1, 2-dithiole-3-thione through the ERK signaling pathway in murine keratinocytes.","17854798",40]
["1,2-dithiol-3-thione","1,2-dithiol-3-thione","C049325","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1733561","Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats.","1733561",40]
["1,2-epoxy-3-(p-nitrophenoxy)propane","1,2-epoxy-3-(p-nitrophenoxy)propane","C007606","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1998,"9504260","Allergic contact dermatitis from epoxy propane.","9504260",40]
["1,2-ethanediol,1-phenyl-1,2-diacetate","1,2-ethanediol,1-phenyl-1,2-diacetate","C577688","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22406575","Fragrance material review on 1,2-ethanediol, 1-phenyl-, 1,2-diacetate.","22406575",40]
["1,2-hexanediol","1,2-hexanediol","C119102","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2009,"19514921","Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol.","19514921",40]
["1,2-hexanediol","1,2-hexanediol","C119102","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21669264","Synergistic effect of 1,4-cyclohexanediol and 1,2-hexanediol on percutaneous absorption and penetration of metronidazole.","21669264",40]
["1,2-hexanoylphosphatidylcholine","1,2-hexanoylphosphatidylcholine","C032166","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2001,"11311244","Sub-micellar phospholipid accelerates amyloid formation by apolipoprotein C-II.","11311244",40]
["1,2-hexanoylphosphatidylcholine","1,2-hexanoylphosphatidylcholine","C032166","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19537801","Lipids enhance apolipoprotein C-II-derived amyloidogenic peptide oligomerization but inhibit fibril formation.","19537801",40]
["1,2-hexanoylphosphatidylcholine","1,2-hexanoylphosphatidylcholine","C032166","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2009,"19432456","Lipid nanostructures: self-assembly and effect on skin properties.","19432456",40]
["1,2-indanedione","1,2-indanedione","C413384","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12873147","Investigating the origin of the slow-binding inhibition of HCV NS3 serine protease by a novel substrate based inhibitor.","12873147",40]
["1,2-indanedione","1,2-indanedione","C413384","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19396020","Spectroscopic investigations of the binding interaction of a new indanedione derivative with human and bovine serum albumins.","19396020",40]
["1,2-indanedione","1,2-indanedione","C413384","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"20676971","Small molecule inhibitors of the human papillomavirus E1-E2 interaction.","20676971",40]
["1,2-isopropylidene-6-chloro-deoxyglucofuranose","1,2-isopropylidene-6-chloro-deoxyglucofuranose","C055776","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1987,"2834162","[Effect of decrease in calcium ion concentration and pH in mitogen-stimulated thymocytes during treatment with synthetic cycloamidophosphates of glucofuranoses].","2834162",40]
["1,2-linoleoylphosphatidylcholine","1,2-linoleoylphosphatidylcholine","C002448","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14507700","Solid-state NMR investigation of the depth of insertion of protegrin-1 in lipid bilayers using paramagnetic Mn2+.","14507700",40]
["1,2-linoleoylphosphatidylcholine","1,2-linoleoylphosphatidylcholine","C002448","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15339796","Dynamic structure of vesicle-bound melittin in a variety of lipid chain lengths by solid-state NMR.","15339796",40]
["1,2-linoleoylphosphatidylcholine","1,2-linoleoylphosphatidylcholine","C002448","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27742354","Polyunsaturated chains in asymmetric lipids disorder raft mixtures and preferentially associate with α-Synuclein.","27742354",40]
["1,2-naphthoquinone","1,2-naphthoquinone","C040756","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12151627","Stability of hemoglobin and albumin adducts of naphthalene oxide, 1,2-naphthoquinone, and 1,4-naphthoquinone.","12151627",40]
["1,2-naphthoquinone","1,2-naphthoquinone","C040756","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12385719","Measurement of hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone after administration of naphthalene to F344 rats.","12385719",40]
["1,2-naphthoquinone","1,2-naphthoquinone","C040756","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"21139334","Immunochemical method to detect proteins that undergo selective modification by 1,2-naphthoquinone derived from naphthalene through metabolic activation.","21139334",40]
["1,2-naphthoquinone","1,2-naphthoquinone","C040756","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"22129745","Peroxiredoxin 6 is a molecular target for 1,2-naphthoquinone, an atmospheric electrophile, in human pulmonary epithelial A549 cells.","22129745",40]
["1,2-naphthoquinone","1,2-naphthoquinone","C040756","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"24067727","Activation of EGFR/MEK/ERK/AP-1 signaling mediated by 1,2-naphthoquinone, an atmospheric electrophile, in human pulmonary A549 cells.","24067727",40]
["1,2-O-bis(8-(2-(2-pentylcyclopropylmethyl)cyclopropyl)octanoyl)-sn-glycero-3-phosphatidylethanolamine","1,2-O-bis(8-(2-(2-pentylcyclopropylmethyl)cyclopropyl)octanoyl)-sn-glycero-3-phosphatidylethanolamine","C000607905","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23594444","Effects of newly synthesized DCP-LA-phospholipids on protein kinase C and protein phosphatases.","23594444",40]
["1,2-octanediol","1,2-octanediol","C535047","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2009,"19514921","Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol.","19514921",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2003,"12540796","Modulation of cellular immune response against hepatitis C virus nonstructural protein 3 by cationic liposome encapsulated DNA immunization.","12540796",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11867462","Structure, composition, and peptide binding properties of detergent soluble bilayers and detergent resistant rafts.","11867462",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12962277","Specificity of membrane binding of the neuronal protein NAP-22.","12962277",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14763851","Affinity purification of lipid vesicles.","14763851",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15321714","Phospholipid catalysis of diabetic amyloid assembly.","15321714",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15454440","Interaction of melittin with membrane cholesterol: a fluorescence approach.","15454440",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16807052","Electrochemical screening of self-assembling beta-sheet peptides using supported phospholipid monolayers.","16807052",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18502811","Sorting of streptavidin protein coats on phase-separating model membranes.","18502811",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19714900","Specular neutron reflectivity studies of the interaction of cytochrome c with supported phosphatidylcholine bilayers doped with phosphatidylserine.","19714900",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23415670","Free energy of WALP23 dimer association in DMPC, DPPC, and DOPC bilayers.","23415670",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23643891","Insertion of TAT peptide and perturbation of negatively charged model phospholipid bilayer revealed by neutron diffraction.","23643891",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24107937","Multiplexed biomimetic lipid membranes on graphene by dip-pen nanolithography.","24107937",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25103814","Comparing crystal structures of Ca(2+) -ATPase in the presence of different lipids.","25103814",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25172666","Surface features of the lipid droplet mediate perilipin 2 localization.","25172666",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25445669","The role of tryptophans on the cellular uptake and membrane interaction of arginine-rich cell penetrating peptides.","25445669",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27366981","Structure prediction and functional analyses of a thermostable lipase obtained from Shewanella putrefaciens.","27366981",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27806910","Structure and function of PspA and Vipp1 N-terminal peptides: Insights into the membrane stress sensing and mitigation.","27806910",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28653654","MPP1 interacts with DOPC/SM/Cholesterol in an artificial membrane system using Langmuir-Blodgett monolayer.","28653654",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28709976","Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center.","28709976",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3768326","A domain of membrane-bound blood coagulation factor Va is located far from the phospholipid surface. A fluorescence energy transfer measurement.","3768326",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6307366","Cooperative lipid activation of (Na+ + K+)-ATPASE as a consequence of non-cooperative lipid-protein interactions.","6307366",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6826567","Clathrin-induced pH-dependent fusion of phosphatidylcholine vesicles.","6826567",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6860639","Interaction of bovine blood clotting factor Va and its subunits with phospholipid vesicles.","6860639",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7577961","Inhibition of prothrombinase at macroscopic lipid membranes: competition between antithrombin and prothrombin.","7577961",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"7690593","Temperature dependence of the interaction of alamethicin helices in membranes.","7690593",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8889162","Reversible adsorption and nonreversible insertion of Escherichia coli alpha-hemolysin into lipid bilayers.","8889162",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"9172747","Critical micelle concentrations and stirring are rate limiting in the loss of lipid mass during membrane degradation by phospholipase A2.","9172747",40]
["1,2-oleoylphosphatidylcholine","1,2-oleoylphosphatidylcholine","C017251","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23269481","Characterization of new DOPC/DHPC platform for dermal applications.","23269481",40]
["1,3(2H,4H)-isoquinolinedione","1,3(2H,4H)-isoquinolinedione","C472069","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24722522","Insight into the interactions between novel isoquinolin-1,3-dione derivatives and cyclin-dependent kinase 4 combining QSAR and molecular docking.","24722522",40]
["1,3,4-butanetriol","1,3,4-butanetriol","C114589","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10092841","Probing the role of C-1 ester group in Naja naja phospholipase A2-phospholipid interactions using butanetriol-containing phosphatidylcholine analogues.","10092841",40]
["1,3,4-oxadiazol-2(3H)-one","1,3,4-oxadiazol-2(3H)-one","C586624","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26344596","Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors.","26344596",40]
["1,3,4-oxadiazole","1,3,4-oxadiazole","C583463","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25146684","Synthesis and structure-activity relationship studies of 2-(1,3,4-oxadiazole-2(3H)-thione)-3-amino-5-arylthieno[2,3-b]pyridines as inhibitors of DRAK2.","25146684",40]
["1,3,4-oxadiazole","1,3,4-oxadiazole","C583463","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27343854","Synthesis, characterization and interaction studies of 1,3,4-oxadiazole derivatives of fatty acid with human serum albumin (HSA): A combined multi-spectroscopic and molecular docking study.","27343854",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1091,B1091)","v":"1,3,4-thiadiazole"},"1,3,4-thiadiazole","C058949","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1091,K1091)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2011,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1091,Q1091)","v":"21889345"},"Synthesis, biological evaluation and molecular docking studies of 1,3,4-thiadiazole derivatives containing 1,4-benzodioxan as potential antitumor agents.","21889345",40]
["1,3,4-thiadiazole","1,3,4-thiadiazole","C058949","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25985954","Biological and pharmacological activities of 1,3,4-thiadiazole based compounds.","25985954",40]
["1,3,4-thiadiazole","1,3,4-thiadiazole","C058949","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"26999261","Determination on the binding of thiadiazole derivative to human serum albumin: a spectroscopy and computational approach.","26999261",40]
["1,3,4-trihydroxy-5-cyclohexene-1-carboxylic acid","1,3,4-trihydroxy-5-cyclohexene-1-carboxylic acid","C480611","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14667226","Parallel solid-phase synthesis and evaluation of inhibitors of Streptomyces coelicolor type II dehydroquinase.","14667226",40]
["1,3,4-trihydroxycyclohex-5-en-1-carboxylic acid","1,3,4-trihydroxycyclohex-5-en-1-carboxylic acid","C502985","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16033267","Structure-based design, synthesis, and biological evaluation of inhibitors of Mycobacterium tuberculosis type II dehydroquinase.","16033267",40]
["1,3,5,8-tetrahydroxyxanthone","1,3,5,8-tetrahydroxyxanthone","C574093","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24482356","Xanthones from Swertia mussotii as multitarget-directed antidiabetic agents.","24482356",40]
["1,3,5-triacryloylhexahydrotriazine","1,3,5-triacryloylhexahydrotriazine","C049485","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1986,"3726891","Studies on the acute toxicity primary irritancy and genotoxic potential of 1,3,5-triacryloylhexahydro-s-triazine (TAHT).","3726891",40]
["1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole","1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole","C419153","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"26397183","Pharmacological activation of estrogen receptors-α and -β differentially modulates keratinocyte differentiation with functional impact on wound healing.","26397183",40]
["1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole","1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole","C419153","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"26397183","Pharmacological activation of estrogen receptors-α and -β differentially modulates keratinocyte differentiation with functional impact on wound healing.","26397183",40]
["1,3,6-naphthalenetrisulfonate","1,3,6-naphthalenetrisulfonate","C114532","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9719643","Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas.","9719643",40]
["1,3,6-tri-O-galloylglucopyranose","1,3,6-tri-O-galloylglucopyranose","C106217","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9154941","Multiple interactions between polyphenols and a salivary proline-rich protein repeat result in complexation and precipitation.","9154941",40]
["1,3,7,9-tetramethyluric acid","1,3,7,9-tetramethyluric acid","C077059","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11846444","Caffeine and other xanthines as cytochemical blockers and removers of heterocyclic DNA intercalators from chromatin.","11846444",40]
["1,3-benzodioxole-5-propanol,alpha-methyl-5-acetate","1,3-benzodioxole-5-propanol,alpha-methyl-5-acetate","C577690","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22406568","Fragrance material review on 1,3-benzodioxole-5-propanol, α-methyl-, 5-acetate.","22406568",40]
["1,3-benzthiazinan-4-one","1,3-benzthiazinan-4-one","C543931","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19596198","Design and synthesis of new 1,3-benzthiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.","19596198",40]
["1,3-bis(14-methylpentadecanoyl)glycerol","1,3-bis(14-methylpentadecanoyl)glycerol","C090384","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"7951153","Studies on thermophile products. VII. Effect of 1,3-di-14-methylpentadecanoyl glycerol and its related isofatty acids on T cell proliferation in vitro.","7951153",40]
["1,3-bis(4-amidinophenoxy)-2-(4-amidinophenoxymethyl)ethylpropane","1,3-bis(4-amidinophenoxy)-2-(4-amidinophenoxymethyl)ethylpropane","C074442","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1284429","Inhibition of human alpha-, beta- and gamma-thrombin by mono-, bis-, tris- and tetra-benzamidine structures: thermodynamic study.","1284429",40]
["1,3-bis(4-amidinophenoxy)-2-(4-amidinophenoxymethyl)ethylpropane","1,3-bis(4-amidinophenoxy)-2-(4-amidinophenoxymethyl)ethylpropane","C074442","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2001,"11572598","Aromatic polyamidines inhibiting the Tat-induced HIV-1 transcription recognize structured TAR-RNA.","11572598",40]
["1,3-bis(pyridin-2-ylethynyl)benzene","1,3-bis(pyridin-2-ylethynyl)benzene","C573496","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22267204","Structure-activity relationships for negative allosteric mGluR5 modulators.","22267204",40]
["1,3-butadiene","1,3-butadiene","C031763","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2001,"11397416","Comparative toxicity of dithiocarbamates and butadiene metabolites in human lymphoid and bone marrow cells.","11397416",40]
["1,3-butadiene","1,3-butadiene","C031763","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1953,"13103828","Synthetic rubbers; their chemistry and dermatological aspects.","13103828",40]
["1,3-butadiene","1,3-butadiene","C031763","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1986,"3705101","Alkylation of nuclear proteins and DNA after exposure of rats and mice to [1,4-14C]1,3-butadiene.","3705101",40]
["1,3-butadiene","1,3-butadiene","C031763","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1999,"10434027","Mutagenicity of 1,3-butadiene at the Hprt locus of T-lymphocytes following inhalation exposures of female mice and rats.","10434027",40]
["1,3-butadiene","1,3-butadiene","C031763","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"10648904","Comparison of the mutations at Hprt exon 3 of T-lymphocytes from B6C3F1 mice and F344 rats exposed by inhalation to 1,3-butadiene or the racemic mixture of 1,2:3,4-diepoxybutane.","10648904",40]
["1,3-butadiene","1,3-butadiene","C031763","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2001,"11397400","Mutagenicity at the Hprt locus in T cells of female mice following inhalation exposures to low levels of 1,3-butadiene.","11397400",40]
["1,3-butadiene","1,3-butadiene","C031763","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2004,"14991748","Characterization of Hprt mutations in cDNA and genomic DNA of T-cell mutants from control and 1,3-butadiene-exposed male B6C3F1 mice and F344 rats.","14991748",40]
["1,3-butadiene","1,3-butadiene","C031763","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"16945358","Age-, gender-, and species-dependent mutagenicity in T cells of mice and rats exposed by inhalation to 1,3-butadiene.","16945358",40]
["1,3-butadiene","1,3-butadiene","C031763","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1998,"9667740","Comparison of the mutagenic potency of 1,3-butadiene at the hprt locus of T-lymphocytes following inhalation exposure of female B6C3F1 mice and F344 rats.","9667740",40]
["1,3-butadiene","1,3-butadiene","C031763","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"7520989","Development of a cloning assay with high cloning efficiency to detect induction of 6-thioguanine-resistant lymphocytes in spleen of adult mice following in vivo inhalation exposure to 1,3-butadiene.","7520989",40]
["1,3-butadiene","1,3-butadiene","C031763","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1993,"8070866","Mutagenicity of 1,3-butadiene and its epoxide metabolites in human TK6 cells and in splenic T cells isolated from exposed B6C3F1 mice.","8070866",40]
["1,3-butanediol-1,3-dioctanoate","1,3-butanediol-1,3-dioctanoate","C019282","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1980,"7433367","Effects of 1,3-butanediol-1,3-dioctanoate and corn oil on lipids of chick plasma, liver, and skin.","7433367",40]
["1,3-butylene glycol","1,3-butylene glycol","C028491","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"11011933","Allergic contact dermatitis due to 1,3-butylene glycol.","11011933",40]
["1,3-butylene glycol","1,3-butylene glycol","C028491","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2004,"15291838","Allergic contact dermatitis due to 1,3-butylene glycol in medicaments.","15291838",40]
["1,3-butylene glycol","1,3-butylene glycol","C028491","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"16285485","[Allergic contact eczema from shellac and 1,3-butylene glycol in an eyeliner].","16285485",40]
["1,3-butylene glycol","1,3-butylene glycol","C028491","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2007,"17441866","Allergic contact dermatitis due to 1,3-butylene glycol and glycerol.","17441866",40]
["1,3-butylene glycol","1,3-butylene glycol","C028491","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2014,"25182293","Case of allergic contact dermatitis due to 1,3-butylene glycol.","25182293",40]
["1,3-butylene glycol","1,3-butylene glycol","C028491","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1997,"9285172","Contact dermatitis due to 1,3-butylene glycol.","9285172",40]
["1,3-butylene glycol","1,3-butylene glycol","C028491","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2003,"16285485","[Allergic contact eczema from shellac and 1,3-butylene glycol in an eyeliner].","16285485",40]
["1,3-butylene glycol","1,3-butylene glycol","C028491","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27430380","Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum.","27430380",40]
["1,3-di-(1-pyrenyl)propane","1,3-di-(1-pyrenyl)propane","C035116","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"7150417","An intramolecular excimer forming probe used to study the interaction of alpha-lactalbumin with model membranes.","7150417",40]
["1,3-di-(4-amidinophenoxy)-2,2-bis-(4-amidinophenoxymethyl)propane","1,3-di-(4-amidinophenoxy)-2,2-bis-(4-amidinophenoxymethyl)propane","C057885","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2001,"11572598","Aromatic polyamidines inhibiting the Tat-induced HIV-1 transcription recognize structured TAR-RNA.","11572598",40]
["1,3-di-(N-propyloxymannopyranosyl)carbamoyl-5-methylazidobenzene","1,3-di-(N-propyloxymannopyranosyl)carbamoyl-5-methylazidobenzene","C115881","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9757127","Crystallization of succinylated concanavalin A bound to a synthetic bivalent ligand and preliminary structural analysis.","9757127",40]
["1,3-dibenzyl-5,6--dihydroxy-4,7-di-(phenoxymethyl)-1,3-azepin-2-one","1,3-dibenzyl-5,6--dihydroxy-4,7-di-(phenoxymethyl)-1,3-azepin-2-one","C105324","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9083478","Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitor.","9083478",40]
["1,3-dibenzyl-5,6-dihydroxy-4,7-di-(phenoxymethyl)-2-thia-1,3-azepine S,S-dioxide","1,3-dibenzyl-5,6-dihydroxy-4,7-di-(phenoxymethyl)-2-thia-1,3-azepine S,S-dioxide","C105323","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9083478","Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitor.","9083478",40]
["1,3-dibromo-2,4,6-tris-(methylisothiouronium)benzene","1,3-dibromo-2,4,6-tris-(methylisothiouronium)benzene","C108416","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2005,"15746094","Interference with phosphoenzyme isomerization and inhibition of the sarco-endoplasmic reticulum Ca2+ ATPase by 1,3-dibromo-2,4,6-tris(methylisothiouronium) benzene.","15746094",40]
["1,3-dibutyl-2-thiourea","1,3-dibutyl-2-thiourea","C034546","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2004,"15573652","Allergic contact dermatitis from dibutylthiourea in a wet suit.","15573652",40]
["1,3-dibutyl-2-thiourea","1,3-dibutyl-2-thiourea","C034546","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2008,"18674454","Positive patch-test reactions to mixed dialkyl thioureas: cross-sectional data from the North American Contact Dermatitis Group, 1994 to 2004.","18674454",40]
["1,3-dibutyl-2-thiourea","1,3-dibutyl-2-thiourea","C034546","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2010,"20597932","Sensitization to thiourea derivatives among Finnish patients with suspected contact dermatitis.","20597932",40]
["1,3-dibutyl-2-thiourea","1,3-dibutyl-2-thiourea","C034546","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2015,"25532938","Investigation of diethylthiourea and ethyl isothiocyanate as potent skin allergens in chloroprene rubber.","25532938",40]
["1,3-dibutyl-2-thiourea","1,3-dibutyl-2-thiourea","C034546","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"7634791","Contact dermatitis due to occupational dibutylthiourea exposure: a case of phonecard dermatitis.","7634791",40]
["1,3-dibutyl-2-thiourea","1,3-dibutyl-2-thiourea","C034546","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1998,"9687044","Occupational airborne allergic contact dermatitis from dibutylthiourea.","9687044",40]
["1,3-dibutyl-2-thiourea","1,3-dibutyl-2-thiourea","C034546","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"3130217","Contact dermatitis to thioureas.","3130217",40]
["1,3-dibutyl-2-thiourea","1,3-dibutyl-2-thiourea","C034546","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1985,"3937662","Contact dermatitis to dibutylthiourea in swimming goggles.","3937662",40]
["1,3-dibutyl-2-thiourea","1,3-dibutyl-2-thiourea","C034546","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1982,"6806056","[A case of allergy to dibutylthiourea caused by diver's footgear (author's transl)].","6806056",40]
["1,3-dichloro-1-propene","1,3-dichloro-1-propene","C023891","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"14531879","Allergic contact dermatitis due to 1,3-dichloropropene soil fumigant.","14531879",40]
["1,3-dichloro-1-propene","1,3-dichloro-1-propene","C023891","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"19018104","Structural and mechanistic analysis of trans-3-chloroacrylic acid dehalogenase activity.","19018104",40]
["1,3-dichloro-6-trifluoromethyl-9-phenanthryl-3-(n-butyl)aminopropanol","1,3-dichloro-6-trifluoromethyl-9-phenanthryl-3-(n-butyl)aminopropanol","C044961","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11891669","Stereoselective halofantrine and desbutylhalofantrine disposition in the rat: cardiac and plasma concentrations and plasma protein binding.","11891669",40]
["1,3-dichloro-6-trifluoromethyl-9-phenanthryl-3-(n-butyl)aminopropanol","1,3-dichloro-6-trifluoromethyl-9-phenanthryl-3-(n-butyl)aminopropanol","C044961","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"18972574","The effect of experimental hyperlipidemia on the stereoselective tissue distribution, lipoprotein association and microsomal metabolism of (+/-)-halofantrine.","18972574",40]
["1,3-dicyclopentyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylic acid diethyl ester","1,3-dicyclopentyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylic acid diethyl ester","C587910","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2013,"23791971","Anti-inflammatory and immunosuppressive activities of 1,3-dicyclopentyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylic acid diethyl ester (ZL-5015).","23791971",40]
["1,3-didecanoylglycerol","1,3-didecanoylglycerol","C030829","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7240252","The adsorption to and hydrolysis of 1,3-didecanoyl glycerol monolayers by pancreatic lipase. Effects of substrate packing density.","7240252",40]
["1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one","1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one","C532657","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2014,"25336630","Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy.","25336630",40]
["1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate","1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate","C503118","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,-1,2005,"15821026","JTP-27536 [(+)-1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-[(R)-3-cyclo-hexyl-1-phenylpropyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate], a novel inhibitor of immunoglobulins and interleukin-5 with anti-inflammatory properties in mouse allergic dermatitis model.","15821026",40]
["1,3-diisopropylcarbodiimide","1,3-diisopropylcarbodiimide","C081611","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1998,"9598300","Contact hypersensitivity to dicyclohexylcarbodiimide and diisopropylcarbodiimide in female B6C3F1 mice.","9598300",40]
["1,3-diisopropylcarbodiimide","1,3-diisopropylcarbodiimide","C081611","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"18784767","Toxicology study of diispropylcarbodiimide (CAS No. 693-13-0) in genetically modified (FVB Tg.AC Hemizygous) mice and carcinogenicity study of diispropylcarbodiimide in genetically modified [B6.129-Trp53tm1Brd (N5) haploinsufficient] mice (dermal studies).","18784767",40]
["1,3-diisopropylcarbodiimide","1,3-diisopropylcarbodiimide","C081611","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22060820","Comparative dermal toxicity of dicyclohexylcarbodiimide and diisopropylcarbodiimide in rodents.","22060820",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1155,B1155)","v":"1,3-dimethyl-3-butenyl salicylate"},"1,3-dimethyl-3-butenyl salicylate","C526484","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1155,K1155)","v":"Skin"},"D012867","Skin",0,1,2007,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1155,Q1155)","v":"18022747"},"Fragrance material review on 1,3-dimethyl-3-butenyl salicylate.","18022747",40]
["1,3-dimethyl-3-phenylbutyl acetate","1,3-dimethyl-3-phenylbutyl acetate","C577681","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22406562","Fragrance material review on 1,3-dimethyl-3-phenylbutyl acetate.","22406562",40]
["1,3-dimethylbenzimidazoline-2-thione","1,3-dimethylbenzimidazoline-2-thione","C078257","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1446015","Metabolism of benzimidazoline-2-thiones by rat hepatic microsomes and hog liver flavin-containing monooxygenase.","1446015",40]
["1,3-dimethylol-5,5-dimethylhydantoin","1,3-dimethylol-5,5-dimethylhydantoin","C056057","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2002,"12225423","Contact allergy from DMDM hydantoin, 1994-2000.","12225423",40]
["1,3-dimethylol-5,5-dimethylhydantoin","1,3-dimethylol-5,5-dimethylhydantoin","C056057","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"3378426","Patch test reactivity to DMDM hydantoin. Relationship to formaldehyde allergy.","3378426",40]
["1,3-dimethylurea","1,3-dimethylurea","C018276","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26625778","In silico docking of methyl isocyanate (MIC) and its hydrolytic product (1, 3-dimethylurea) shows significant interaction with DNA Methyltransferase 1 suggests cancer risk in Bhopal-Gas- Tragedy survivors.","26625778",40]
["1,3-dimethyluric acid","1,3-dimethyluric acid","C031274","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17847127","Effects of water deprivation on the pharmacokinetics of theophylline and one of its metabolites, 1,3-dimethyluric acid, after intravenous and oral administration of aminophylline to rats.","17847127",40]
["1,3-dimethyluric acid","1,3-dimethyluric acid","C031274","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2008,"18088504","Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU.","18088504",40]
["1,3-diphenylisobenzofuran","1,3-diphenylisobenzofuran","C011238","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1851398","Cutaneous photoprotection using a hydroxyl radical scavenger in photodynamic therapy.","1851398",40]
["1,3-diphenylisobenzofuran","1,3-diphenylisobenzofuran","C011238","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2522745","Prevention of cutaneous phototoxicity in photodynamic therapy.","2522745",40]
["1,3-dipropyl-8-cyclopentylxanthine","1,3-dipropyl-8-cyclopentylxanthine","C051360","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7788877","Binding of A1 adenosine receptor ligand [3H]8-cyclopentyl-1,3-dipropylxanthine in coronary smooth muscle.","7788877",40]
["1,3-ditolylguanidine","1,3-ditolylguanidine","C050232","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2006,"16529908","Prenatal cocaine alters dopamine and sigma receptor binding in nucleus accumbens and striatum in dams and adolescent offspring.","16529908",40]
["1,3-ditolylguanidine","1,3-ditolylguanidine","C050232","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1996,"8913792","[3H]1,3-di(2-tolyl) guanidine binds to a sigma 2 receptor on Jurkat cell membranes, but sigma compounds fail to influence immunomodulatory events in human peripheral blood lymphocytes.","8913792",40]
["1,3-ditolylguanidine","1,3-ditolylguanidine","C050232","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1996,"8913792","[3H]1,3-di(2-tolyl) guanidine binds to a sigma 2 receptor on Jurkat cell membranes, but sigma compounds fail to influence immunomodulatory events in human peripheral blood lymphocytes.","8913792",40]
["1,3-mannosylmannose","1,3-mannosylmannose","C108662","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26507789","A Rigid Hinge Region Is Necessary for High-Affinity Binding of Dimannose to Cyanovirin and Associated Constructs.","26507789",40]
["1,3-propane sultone","1,3-propane sultone","C003218","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1998,"9891446","Differential growth response to exogenous calcium in normal and carcinogen-exposed primary human keratinocyte cell cultures.","9891446",40]
["1,3-propane sultone","1,3-propane sultone","C003218","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8643558","Malignant conversion of chemically transformed normal human cells.","8643558",40]
["1,3-propane sultone","1,3-propane sultone","C003218","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9891446","Differential growth response to exogenous calcium in normal and carcinogen-exposed primary human keratinocyte cell cultures.","9891446",40]
["1,3-propanediol","1,3-propanediol","C041787","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24002450","Characterization and cofactor binding mechanism of a novel NAD(P)H-dependent aldehyde reductase from Klebsiella pneumoniae DSM2026.","24002450",40]
["1,3-propanediol","1,3-propanediol","C041787","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26481430","1,3-propanediol binds deep inside the channel to inhibit water permeation through aquaporins.","26481430",40]
["1,3-propanediol","1,3-propanediol","C041787","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1958,"13535376","[Effects of 1,2-propanediol on the skin and mucous membranes].","13535376",40]
["1,3-xylenediamine","1,3-xylenediamine","C066883","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2001,"11417528","Occupational contact dermatitis due to the epoxy hardener m-xylylenediamine.","11417528",40]
["1,3-xylenediamine","1,3-xylenediamine","C066883","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1990,"2148720","[Allergic contact eczema caused by m-xylylene-diamine in the polyurethane silk production].","2148720",40]
["1,4-(4-4'-Bis-((4-(dimethylamine)pyridinium-1-yl) methyl)diphenyl)butane dibromide","1,4-(4-4'-Bis-((4-(dimethylamine)pyridinium-1-yl) methyl)diphenyl)butane dibromide","C507944","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27029499","Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1).","27029499",40]
["1,4,7,10-tetraaza-1,4,10-tri(carboxymethyl)-7-(((4-phosphonomethylphenyl)aminocarbonyl)phenyl)dodecane","1,4,7,10-tetraaza-1,4,10-tri(carboxymethyl)-7-(((4-phosphonomethylphenyl)aminocarbonyl)phenyl)dodecane","C417706","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10968620","Ternary Gd(III)L-HSA adducts: evidence for the replacement of inner-sphere water molecules by coordinating groups of the protein. Implications for the design of contrast agents for MRI.","10968620",40]
["1,4,7,10-tetraaza-7-(4-bromophenyl)-1,4,10-tri(carboxymethyl)dodecane","1,4,7,10-tetraaza-7-(4-bromophenyl)-1,4,10-tri(carboxymethyl)dodecane","C417705","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10968620","Ternary Gd(III)L-HSA adducts: evidence for the replacement of inner-sphere water molecules by coordinating groups of the protein. Implications for the design of contrast agents for MRI.","10968620",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,2004,"15120256","Generation of DOTA-conjugated antibody fragments for radioimmunoimaging.","15120256",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12825956","A new biotin derivative-DOTA conjugate as a candidate for pretargeted diagnosis and therapy of tumors.","12825956",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14503959","Design, synthesis, and evaluation of radiolabeled integrin alpha v beta 3 receptor antagonists for tumor imaging and radiotherapy.","14503959",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17340009","Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes.","17340009",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19397856","Evaluation of [64Cu]Cu-DOTA and [64Cu]Cu-CB-TE2A chelates for targeted positron emission tomography with an alphavbeta6-specific peptide.","19397856",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20056547","Design, synthesis and in vitro characterization of Glucagon-Like Peptide-1 derivatives for pancreatic beta cell imaging by SPECT.","20056547",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20722424","Design, synthesis, and evaluation of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid derived, redox-sensitive contrast agents for magnetic resonance imaging.","20722424",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20926300","Synthesis and evaluation of macrocyclic amino acid derivatives for tumor imaging by gallium-68 positron emission tomography.","20926300",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21328514","Spacer effects on in vivo properties of DOTA-conjugated dimeric [Tyr3]octreotate peptides synthesized by a \"Cu(I)-click\" and \"sulfo-click\" ligation method.","21328514",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21461972","The interaction of La(3+) complexes of DOTA/DTPA glycoconjugates with the RCA(120) lectin: a saturation transfer difference NMR spectroscopic study.","21461972",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21523391","Comparison of the binding and internalization properties of 12 DOTA-coupled and ¹¹¹In-labelled CCK2/gastrin receptor binding peptides: a collaborative project under COST Action BM0607.","21523391",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"22068898","Evaluation of 177Lu-DOTA-sst2 antagonist versus 177Lu-DOTA-sst2 agonist binding in human cancers in vitro.","22068898",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22172391","68Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers.","22172391",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22187146","Site-specific DOTA/europium-labeling of recombinant human relaxin-3 for receptor-ligand interaction studies.","22187146",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22768790","Influence of DOTA chelator position on biodistribution and targeting properties of (111)In-labeled synthetic anti-HER2 affibody molecules.","22768790",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24378707","[DOTA]Somatostatin-14 analogs and their (111)In-radioligands: effects of decreasing ring-size on sst1-5 profile, stability and tumor targeting.","24378707",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24408895","Imaging of platelet-derived growth factor receptor β expression in glioblastoma xenografts using affibody molecule 111In-DOTA-Z09591.","24408895",40]
["1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24922178","Gd(DOTAlaP): exploring the boundaries of fast water exchange in gadolinium-based magnetic resonance imaging contrast agents.","24922178",40]
["1,4,7,10-tetraazacyclododecane-1,4,7,10-tetracetic acid","1,4,7,10-tetraazacyclododecane-1,4,7,10-tetracetic acid","C578439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28628723","A Multifunctional Radiotheranostic Agent for Dual Targeting of Breast Cancer Cells.","28628723",40]
["1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid","1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid","C520644","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20722424","Design, synthesis, and evaluation of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid derived, redox-sensitive contrast agents for magnetic resonance imaging.","20722424",40]
["1,4,7-triazacyclononane","1,4,7-triazacyclononane","C075712","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"16964506","An examination of the binding behavior of histidine-containing peptides with immobilized metal complexes derived from the macrocyclic ligand, 1,4,7-triazacyclononane.","16964506",40]
["1,4,7-triazacyclononane","1,4,7-triazacyclononane","C075712","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20184374","Double selective synthetic approach to the N-functionalized 1,4,7-triazacyclononane derivatives: chelating compounds for controllable protein orientation.","20184374",40]
["1,4,7-triazacyclononane","1,4,7-triazacyclononane","C075712","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21429825","Comparison of the binding behavior of several histidine-containing proteins with immobilized copper(II) complexes of 1,4,7-triazacyclononane and 1,4-bis(1,4,7-triazacyclononan-1-yl)butane.","21429825",40]
["1,4,7-triazacyclononane-1,4-diacetate","1,4,7-triazacyclononane-1,4-diacetate","C519451","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22443100","Syntheses of 2-nitroimidazole derivatives conjugated with 1,4,7-triazacyclononane-N,N'-diacetic acid labeled with F-18 using an aluminum complex method for hypoxia imaging.","22443100",40]
["1,4,7-triazacyclononane-N,N',N''-triacetic acid","1,4,7-triazacyclononane-N,N',N''-triacetic acid","C048993","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20926300","Synthesis and evaluation of macrocyclic amino acid derivatives for tumor imaging by gallium-68 positron emission tomography.","20926300",40]
["1,4,7-triazacyclononane-N,N',N''-triacetic acid","1,4,7-triazacyclononane-N,N',N''-triacetic acid","C048993","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23096079","In vivo characterization of 68Ga-NOTA-VEGF 121 for the imaging of VEGF receptor expression in U87MG tumor xenograft models.","23096079",40]
["1,4,7-triazacyclononane-N,N',N''-triacetic acid","1,4,7-triazacyclononane-N,N',N''-triacetic acid","C048993","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25036155","The effect of mini-PEG-based spacer length on binding and pharmacokinetic properties of a 68Ga-labeled NOTA-conjugated antagonistic analog of bombesin.","25036155",40]
["1,4,7-tris(carboxymethyl)-10-(vinylsulfone)-1,4,7,10-tetraazacyclododecane","1,4,7-tris(carboxymethyl)-10-(vinylsulfone)-1,4,7,10-tetraazacyclododecane","C527697","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28891030","Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4.","28891030",40]
["1,4,8-trimethylfuro(2,3-H)quinolin-2(1H)-one","1,4,8-trimethylfuro(2,3-H)quinolin-2(1H)-one","C494223","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2004,"15110967","1,4,8-trimethylfuro[2,3-H]quinolin-2(1H)-one, a new furocoumarin bioisoster.","15110967",40]
["1,4-benzodioxan","1,4-benzodioxan","C527681","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21782456","Oxadiazole derivatives containing 1,4-benzodioxan as potential immunosuppressive agents against RAW264.7 cells.","21782456",40]
["1,4-benzodioxan","1,4-benzodioxan","C527681","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21889345","Synthesis, biological evaluation and molecular docking studies of 1,3,4-thiadiazole derivatives containing 1,4-benzodioxan as potential antitumor agents.","21889345",40]
["1,4-benzothiazine","1,4-benzothiazine","C446962","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19447623","Non-nucleoside inhibitors of HCV NS5B polymerase. Part 1: Synthetic and computational exploration of the binding modes of benzothiadiazine and 1,4-benzothiazine HCV NS5b polymerase inhibitors.","19447623",40]
["1,4-benzothiazine","1,4-benzothiazine","C446962","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"11861815","Induction of apoptosis by 1,4-benzothiazine analogs in mouse thymocytes.","11861815",40]
["1,4-bis((4-((4-heptylpiperazin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)methyl)benzene","1,4-bis((4-((4-heptylpiperazin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)methyl)benzene","C000608078","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25906763","Investigation of Optical Spectroscopic and Computational Binding Mode of Bovine Serum Albumin with 1, 4-Bis ((4-((4-Heptylpiperazin-1-yl) Methyl)-1H-1, 2, 3-Triazol-1-yl) Methyl) Benzene.","25906763",40]
["1,4-bis(2-(3,5-dichloropyridyloxy))benzene","1,4-bis(2-(3,5-dichloropyridyloxy))benzene","C028474","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21220114","Helix 11 dynamics is critical for constitutive androstane receptor activity.","21220114",40]
["1,4-bis(2,3-epoxypropoxy)butane","1,4-bis(2,3-epoxypropoxy)butane","C014376","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2016,"26537833","Sensitization to reactive diluents and hardeners in epoxy resin systems. IVDK data 2002-2011. Part II: concomitant reactions.","26537833",40]
["1,4-bis(2,3-epoxypropoxy)butane","1,4-bis(2,3-epoxypropoxy)butane","C014376","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2016,"26538018","Sensitization to reactive diluents and hardeners in epoxy resin systems. IVDK data 2002-2011. Part I: reaction frequencies.","26538018",40]
["1,4-bis(2,3-epoxypropoxy)butane","1,4-bis(2,3-epoxypropoxy)butane","C014376","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"25990692","Comparative histologic and immunologic evaluation of 1,4-butanediol diglycidyl ether crosslinked versus noncrosslinked acellular swim bladder matrix for healing of full-thickness skin wounds in rabbits.","25990692",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1219,B1219)","v":"1,4-bis(aminocyclohexyl)methane"},"1,4-bis(aminocyclohexyl)methane","C072821","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1219,K1219)","v":"Dermatitis, Contact"},"D003877","Dermatitis, Contact",0,2,1991,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1219,Q1219)","v":"1783741"},"Toxicity of 1,4-bis(aminocyclohexyl)methane.","1783741",40]
["1,4-bis(aminocyclohexyl)methane","1,4-bis(aminocyclohexyl)methane","C072821","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1783741","Toxicity of 1,4-bis(aminocyclohexyl)methane.","1783741",40]
["1,4-bis(aminomethyl)-2,3,5,6-tetrafluorobenzene","1,4-bis(aminomethyl)-2,3,5,6-tetrafluorobenzene","C059795","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1989,"2524357","Allergic contact dermatitis from tetrafluoroterephthalonitrile and TFX diamine.","2524357",40]
["1,4-bis(bromoacetoxy)-2-butene","1,4-bis(bromoacetoxy)-2-butene","C027994","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1980,"6449352","Dermatitis from slimicides in a paper mill.","6449352",40]
["1,4-bis(chloromethyl)benzene","1,4-bis(chloromethyl)benzene","C021150","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1987,"3816216","Contact dermatitis caused by \"chloromethyl heterocyclic intermediates\".","3816216",40]
["1,4-cyclohexanediol","1,4-cyclohexanediol","C064620","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21669264","Synergistic effect of 1,4-cyclohexanediol and 1,2-hexanediol on percutaneous absorption and penetration of metronidazole.","21669264",40]
["1,4-diazepane","1,4-diazepane","C545228","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28764962","Chiral-pool synthesis of 1,2,4-trisubstituted 1,4-diazepanes as novel σ1 receptor ligands.","28764962",40]
["1,4-diethylepipolythiodioxopiperazine","1,4-diethylepipolythiodioxopiperazine","C466230","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"12063251","Influx of calcium through a redox-sensitive plasma membrane channel in thymocytes causes early necrotic cell death induced by the epipolythiodioxopiperazine toxins.","12063251",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2006,"16533816","The cGMP/protein kinase G pathway contributes to dihydropyridine-sensitive calcium response and cytokine production in TH2 lymphocytes.","16533816",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10769189","Conserved Ca2+-antagonist-binding properties and putative folding structure of a recombinant high-affinity dihydropyridine-binding domain.","10769189",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12601159","Modulation of cardiac Ca(V)1.2 channels by dihydropyridine and phosphatase inhibitor requires Ser-1142 in the domain III pore loop.","12601159",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1319724","Dihydropyridine binding of the calcium channel complex from skeletal muscle is modulated by subunit interaction.","1319724",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1992,"1334810","Testosterone sensitive dihydropyridine binding in the Harderian gland of the male hamster.","1334810",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15504730","Opposite effects of a single IIIS5 mutation on phenylalkylamine and dihydropyridine interaction with L-type Ca2+ channels.","15504730",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"20064722","Synthesis and biological activity of the calcium modulator (R) and (S)-3-methyl 5-pentyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.","20064722",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18250364","A number of marketed dihydropyridine calcium channel blockers have mineralocorticoid receptor antagonist activity.","18250364",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18310913","Structure-activity relationships of receptor binding of 1,4-dihydropyridine derivatives.","18310913",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21530277","Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors.","21530277",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"23130626","Synthesis and SAR of b-annulated 1,4-dihydropyridines define cardiomyogenic compounds as novel inhibitors of TGFβ signaling.","23130626",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23688558","Antagonism of L-type Ca2+ channels CaV1.3 and CaV1.2 by 1,4-dihydropyrimidines and 4H-pyrans as dihydropyridine mimics.","23688558",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1987,"2435904","Diethyl 3,6-dihydro-2,4-dimethyl-2,6-methano-1,3-benzothiazocine-5,11- dicarboxylates as calcium entry antagonists: new conformationally restrained analogues of Hantzsch 1,4-dihydropyridines related to nitrendipine as probes for receptor-site conformation.","2435904",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"2461198","Direct coupling of a G-protein to dihydropyridine binding sites.","2461198",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25019089","Development of dual inhibitors against Alzheimer's disease using fragment-based QSAR and molecular docking.","25019089",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26673131","Binding mechanisms of 1,4-dihydropyridine derivatives to L-type calcium channel Cav1.2: a molecular modeling study.","26673131",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28434782","Dimeric isoxazolyl-1,4-dihydropyridines have enhanced binding at the multi-drug resistance transporter.","28434782",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"3157549","Stereospecificity for nicotinamide nucleotides in enzymatic and chemical hydride transfer reactions.","3157549",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8091452","Dihydropyridine ligand binding decreases earlier in adolescent than in infant swine after global cerebral ischemia.","8091452",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9346909","Nine L-type amino acid residues confer full 1,4-dihydropyridine sensitivity to the neuronal calcium channel alpha1A subunit. Role of L-type Met1188.","9346909",40]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"26689352","1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells.","26689352",40]
["1,4-dihydroquinone","1,4-dihydroquinone","C403008","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28645578","The electrophilic character of quinones is essential for the suppression of Bach1.","28645578",40]
["1,4-dihydroquinone","1,4-dihydroquinone","C403008","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10594297","The impact of vehicle on assessment of relative skin sensitization potency of 1,4-dihydroquinone in the local lymph node assay.","10594297",40]
["1,4-dihydroxy-2-nonene","1,4-dihydroxy-2-nonene","C091765","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9101442","Metabolic fate of 4-hydroxynonenal in hepatocytes: 1,4-dihydroxynonene is not the main product.","9101442",40]
["1,4-dimethyl-3,6-epidithio-2,5-dioxopiperazine","1,4-dimethyl-3,6-epidithio-2,5-dioxopiperazine","C048801","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1986,"2422547","Structural relationship of epipolythiodioxopiperazines and their immunomodulating activity.","2422547",40]
["1,4-dioxane","1,4-dioxane","C025223","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1959,"13828973","The inhibition by dioxan of antigen-antibody precipitation. I. Precipitation reactions with protein antigens.","13828973",40]
["1,4-dioxane","1,4-dioxane","C025223","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1960,"13828975","The inhibition by dioxan of antigen-antibody precipitation. II. Precipitin reactions with polysaccharide antigens.","13828975",40]
["1,4-dioxane","1,4-dioxane","C025223","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12209463","Fourier transform IR study of aggregational behavior of N-acetyl-L- and N-butyloxycarbonyl-L-glutamic acid oligomeric benzyl esters in dioxane and benzene: beta-turn --&gt; antiparallel beta-sheet transition.","12209463",40]
["1,4-dioxin","1,4-dioxin","C038902","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2009,"19429259","Induction of S100A4, S100A6, and galectin-1 during the lineage commitment of CD4+CD8+ thymocyte cell line is suppressed by 2,3,7,8-tetrachlorodibenzo-p-dioxin.","19429259",40]
["1,4-dioxin","1,4-dioxin","C038902","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2009,"19429259","Induction of S100A4, S100A6, and galectin-1 during the lineage commitment of CD4+CD8+ thymocyte cell line is suppressed by 2,3,7,8-tetrachlorodibenzo-p-dioxin.","19429259",40]
["1,4-diphenyl-2-mercaptoimidazole","1,4-diphenyl-2-mercaptoimidazole","C545737","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,2009,"19741152","Oral administration of 1,4-aryl-2-mercaptoimidazole inhibits T-cell proliferation and reduces clinical severity in the murine experimental autoimmune encephalomyelitis model.","19741152",40]
["1,4-diphenyl-2-mercaptoimidazole","1,4-diphenyl-2-mercaptoimidazole","C545737","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2009,"19741152","Oral administration of 1,4-aryl-2-mercaptoimidazole inhibits T-cell proliferation and reduces clinical severity in the murine experimental autoimmune encephalomyelitis model.","19741152",40]
["1,4-glucan","1,4-glucan","C040088","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15581376","Alpha-glucan recognition by a new family of carbohydrate-binding modules found primarily in bacterial pathogens.","15581376",40]
["1,4-glucan","1,4-glucan","C040088","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23229556","Understanding how noncatalytic carbohydrate binding modules can display specificity for xyloglucan.","23229556",40]
["1,4-glucan","1,4-glucan","C040088","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23989143","The structure of amylosucrase from Deinococcus radiodurans has an unusual open active-site topology.","23989143",40]
["1,4-glucan","1,4-glucan","C040088","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"2951252","Alpha-glucan synthesis on a protein primer. A reconstituted system for the formation of protein-bound alpha-glucan.","2951252",40]
["1,4-glucan","1,4-glucan","C040088","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3082632","The initiation of glycogen biosynthesis in rat heart alpha-1,4 glucans tightly associated with glycogen synthase.","3082632",40]
["1,4-naphthoquinone","1,4-naphthoquinone","C035342","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"20153715","1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes.","20153715",40]
["1,4-naphthoquinone","1,4-naphthoquinone","C035342","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12151627","Stability of hemoglobin and albumin adducts of naphthalene oxide, 1,2-naphthoquinone, and 1,4-naphthoquinone.","12151627",40]
["1,4-naphthoquinone","1,4-naphthoquinone","C035342","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12385719","Measurement of hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone after administration of naphthalene to F344 rats.","12385719",40]
["1,4-naphthoquinone","1,4-naphthoquinone","C035342","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21267750","Studies on filarial GST as a target for antifilarial drug development-in silico and in vitro inhibition of filarial GST by substituted 1,4-naphthoquinones.","21267750",40]
["1,4-naphthoquinone","1,4-naphthoquinone","C035342","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"22071524","Molecular insights into human monoamine oxidase (MAO) inhibition by 1,4-naphthoquinone: evidences for menadione (vitamin K3) acting as a competitive and reversible inhibitor of MAO.","22071524",40]
["1,4-naphthoquinone","1,4-naphthoquinone","C035342","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"23037999","A method for detecting covalent modification of sensor proteins associated with 1,4-naphthoquinone-induced activation of electrophilic signal transduction pathways.","23037999",40]
["1,4-naphthoquinone","1,4-naphthoquinone","C035342","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"24176397","Antiproliferative activities and SAR studies of substituted anthraquinones and 1,4-naphthoquinones.","24176397",40]
["1,4-naphthoquinone","1,4-naphthoquinone","C035342","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"24288292","Antiallergic effects of pigments isolated from green sea urchin (Strongylocentrotus droebachiensis) shells.","24288292",40]
["1,4-phenanthrenequinone","1,4-phenanthrenequinone","C105959","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"14749026","Structure-activity relationships in allergic contact dermatitis. Part III. The sensitizing capacity of substituted phenanthrenequinones: a quantum-mechanical approach.","14749026",40]
["1,4-phenanthrenequinone","1,4-phenanthrenequinone","C105959","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2008,"18840408","Denbinobin, a naturally occurring 1,4-phenanthrenequinone, inhibits HIV-1 replication through an NF-kappaB-dependent pathway.","18840408",40]
["1,4-phenyldiglyoxal","1,4-phenyldiglyoxal","C018360","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8204621","Effect of nucleotides and actin on the intramolecular cross-linking of myosin subfragment-1.","8204621",40]
["1,4-phenylenebis(methylene)selenocyanate","1,4-phenylenebis(methylene)selenocyanate","C074153","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21732699","Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compounds.","21732699",40]
["1,5-AEDANS","1,5-AEDANS","C048876","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"2964442","Conformational changes in the vicinity of the N-iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine attached to the specific thiol of sarcoplasmic reticulum Ca2+-ATPase throughout the catalytic cycle.","2964442",40]
["1,5-anhydro-1-(5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl)-1-thioglucitol","1,5-anhydro-1-(5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl)-1-thioglucitol","C549343","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20302302","(1S)-1,5-anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-D-glucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment.","20302302",40]
["1,5-anhydro-1-(5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl)-1-thioglucitol","1,5-anhydro-1-(5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl)-1-thioglucitol","C549343","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26354015","[Pharmacological and clinical profile of a new SGLT2 inhibitor, luseogliflozin (Lusefi®)].","26354015",40]
["1,5-anhydroglucitol","1,5-anhydroglucitol","C006584","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,1996,"8852764","Lymphocyte activation effect of (1--&gt;6)-2,5-anhydro-D-glucitol and it derivatives with 3,4-di-O-methyl and sulfate groups.","8852764",40]
["1,5-anhydroglucitol","1,5-anhydroglucitol","C006584","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,1996,"8852764","Lymphocyte activation effect of (1--&gt;6)-2,5-anhydro-D-glucitol and it derivatives with 3,4-di-O-methyl and sulfate groups.","8852764",40]
["1,5-benzothiazepine","1,5-benzothiazepine","C106746","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18397890","Molecular modeling of benzothiazepine binding in the L-type calcium channel.","18397890",40]
["1,5-diazabicyclo(3.1.0)hexane-2,4-dione","1,5-diazabicyclo(3.1.0)hexane-2,4-dione","C417222","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2000,"11076502","Selective inhibition of human Molt-4 leukemia type II inosine 5'-monophosphate dehydrogenase by the 1,5-diazabicyclo[3.1.0]hexane-2,4-diones.","11076502",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1283,B1283)","v":"1,5-difluoro-2,4-dinitrobenzene"},"1,5-difluoro-2,4-dinitrobenzene","C002041","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1283,K1283)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2004,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1283,Q1283)","v":"15218036"},"Oligomerization of ribonuclease A: two novel three-dimensional domain-swapped tetramers.","15218036",40]
["1,5-I-AEDANS","1,5-I-AEDANS","C006421","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2144771","Characterization of the substrate-induced conformational change of N-iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine-labeled sarcoplasmic reticulum Ca2(+)-ATPase by using different kinds of substrate.","2144771",40]
["1,5-I-AEDANS","1,5-I-AEDANS","C006421","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2521338","Changes in the steady-state fluorescence anisotropy of N-iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine attached to the specific thiol of sarcoplasmic reticulum Ca2+-ATPase throughout the catalytic cycle.","2521338",40]
["1,5-I-AEDANS","1,5-I-AEDANS","C006421","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"2931426","N-Iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine modification of myosin from chicken gizzard.","2931426",40]
["1,5-I-AEDANS","1,5-I-AEDANS","C006421","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"2964442","Conformational changes in the vicinity of the N-iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine attached to the specific thiol of sarcoplasmic reticulum Ca2+-ATPase throughout the catalytic cycle.","2964442",40]
["1,5-I-AEDANS","1,5-I-AEDANS","C006421","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"2976460","Chemical derivatization of Ca2+-pump protein from skeletal muscle with N-substituted maleimides and 5-(2-iodoacetamidoethyl)aminonaphthalene 1-sulfonate.","2976460",40]
["1,5-I-AEDANS","1,5-I-AEDANS","C006421","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"4065323","Fluorescent labelling of histone H3: effect on histone-histone interaction and core particle assembly.","4065323",40]
["1,5-I-AEDANS","1,5-I-AEDANS","C006421","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"6893329","A fluorescent probe for conformational changes in skeletal muscle G-actin.","6893329",40]
["1,5-I-AEDANS","1,5-I-AEDANS","C006421","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1982,"6983119","Induction of cell-mediated cytotoxic self responses by epidermal cells modified with a haptenic sulphydryl reagent.","6983119",40]
["1,5-I-AEDANS","1,5-I-AEDANS","C006421","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6983119","Induction of cell-mediated cytotoxic self responses by epidermal cells modified with a haptenic sulphydryl reagent.","6983119",40]
["1,5-pentanediol","1,5-pentanediol","C578469","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"12755747","Allergic contact dermatitis from pentylene glycol in an emollient cream, with possible co-sensitization to resveratrol.","12755747",40]
["1,5-pentanediol","1,5-pentanediol","C578469","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2008,"18186759","Allergic contact dermatitis to pentylene glycol in a cosmetic cream.","18186759",40]
["1,5-pentanediol","1,5-pentanediol","C578469","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2010,"20546226","Allergic contact dermatitis to propyl gallate and pentylene glycol in an emollient cream.","20546226",40]
["1,6,9,12,15,18-henicosahexaene","1,6,9,12,15,18-henicosahexaene","C000592658","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24495846","Lipoxygenase inhibitors derived from marine macroalgae.","24495846",40]
["1,6,9,12,15-henicosapentaene","1,6,9,12,15-henicosapentaene","C000592657","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24495846","Lipoxygenase inhibitors derived from marine macroalgae.","24495846",40]
["1,6-anhydro-beta-glucopyranose","1,6-anhydro-beta-glucopyranose","C014989","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26354439","Producing glucose 6-phosphate from cellulosic biomass: structural insights into levoglucosan bioconversion.","26354439",40]
["1,6-bis(4,7-diaza-6-methyl-5-oxo-3-((2-((5-(phenylthio)tetrazol-1-yl)methyl)pyrrolidin-1-yl)carbonyl)octyloxy)-2,4-hexadiyne","1,6-bis(4,7-diaza-6-methyl-5-oxo-3-((2-((5-(phenylthio)tetrazol-1-yl)methyl)pyrrolidin-1-yl)carbonyl)octyloxy)-2,4-hexadiyne","C491032","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15353788","Medicine. Targeting apoptotic pathways in cancer cells.","15353788",40]
["1,6-bis(4,7-diaza-6-methyl-5-oxo-3-((2-((5-(phenylthio)tetrazol-1-yl)methyl)pyrrolidin-1-yl)carbonyl)octyloxy)-2,4-hexadiyne","1,6-bis(4,7-diaza-6-methyl-5-oxo-3-((2-((5-(phenylthio)tetrazol-1-yl)methyl)pyrrolidin-1-yl)carbonyl)octyloxy)-2,4-hexadiyne","C491032","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15353805","A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death.","15353805",40]
["1,6-bis(carboxyphenoxy)hexane","1,6-bis(carboxyphenoxy)hexane","C120991","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2009,"19539989","The simultaneous effect of polymer chemistry and device geometry on the in vitro activation of murine dendritic cells.","19539989",40]
["1,6-diaminohexane","1,6-diaminohexane","C007297","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1954,"13219576","[Skin lesions caused by hexamethylenediamine].","13219576",40]
["1,6-diaminohexane","1,6-diaminohexane","C007297","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1952,"14953590","[Dermatitis caused by hexamethylenediamine].","14953590",40]
["1,6-diaminohexane","1,6-diaminohexane","C007297","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2007,"17454030","Review of the toxicology of three alkyl diamines.","17454030",40]
["1,6-dinitropyrene","1,6-dinitropyrene","C033309","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10814878","Inhibition of benzo[a]pyrene- and 1,6-dinitropyrene-DNA adduct formation in human mammary epithelial cells bydibenzoylmethane and sulforaphane.","10814878",40]
["1,6-dinitropyrene","1,6-dinitropyrene","C033309","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"11381742","DNA adduct formation and T lymphocyte mutation induction in F344 rats implanted with tumorigenic doses of 1,6-dinitropyrene.","11381742",40]
["1,6-dinitropyrene","1,6-dinitropyrene","C033309","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"7757982","DNA adduct formation and T-lymphocyte mutation induction in F344 rats implanted with tumorigenic doses of 1,6-dinitropyrene.","7757982",40]
["1,6-dinitropyrene","1,6-dinitropyrene","C033309","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1997,"9330623","Analysis of mutations in the K-ras and p53 genes of lung tumors and in the hprt gene of 6-thioguanine-resistant T-lymphocytes from rats treated with 1,6-dinitropyrene.","9330623",40]
["1,6-galactan","1,6-galactan","C044347","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24693939","Galactosyltransferases from Arabidopsis thaliana in the biosynthesis of type II arabinogalactan: molecular interaction enhances enzyme activity.","24693939",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2003,"12743574","Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation.","12743574",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2003,"12743574","Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation.","12743574",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2014,"24742817","Respiratory sensitizer hexamethylene diisocyanate inhibits SOD 1 and induces ERK-dependent detoxifying and maturation pathways in dendritic-like cells.","24742817",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"12786730","Allergic contact dermatitis from 1,6-hexamethylene diisocyanate in a domestic setting.","12786730",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"14531868","Allergic contact dermatitis from dicyclohexylmethane-4,4'-diisocyanate.","14531868",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2008,"18759878","Contact sensitization to 4,4'-diaminodiphenylmethane and to isocyanates among general dermatology patients.","18759878",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2013,"22411214","Skin symptoms in bakery and auto body shop workers: associations with exposure and respiratory symptoms.","22411214",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2012,"22428543","Occupational contact allergy to monomeric isocyanates.","22428543",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2000,"10706755","Too hot to handle: an unusual exposure of HDI in specialty painters.","10706755",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1834431","Allergic contact dermatitis from 1,6-diisocyanatohexane in an anti-pill finish.","1834431",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,2014,"24683011","Exhaled nitric oxide in spray painters exposed to isocyanates: effect modification by atopy and smoking.","24683011",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,1988,"2854010","Experiences of specific IgE in asthma due to diisocyanates.","2854010",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2000,"11112159","Identification of human lung and skin proteins conjugated with hexamethylene diisocyanate in vitro and in vivo.","11112159",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12628819","Enzyme induced biodegradation of polycarbonate-polyurethanes: dose dependence effect of cholesterol esterase.","12628819",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1799650","Covalent immobilization of proteins on to the surface of poly(vinyl alcohol) hydrogel.","1799650",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"11112159","Identification of human lung and skin proteins conjugated with hexamethylene diisocyanate in vitro and in vivo.","11112159",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2001,"11964686","Recent developments in diisocyanate asthma.","11964686",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2003,"12772950","Recent developments in diisocyanate asthma.","12772950",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"16804626","Tape-strip sampling for measuring dermal exposure to 1,6-hexamethylene diisocyanate.","16804626",40]
["1,6-hexamethylene diisocyanate","1,6-hexamethylene diisocyanate","C015262","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2000,"11007611","The foreign body reaction to a biodegradable biomaterial differs between rats and mice.","11007611",40]
["1,6-hexanediol diacrylate","1,6-hexanediol diacrylate","C020355","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"10954995","1,6-hexanediol diacrylate: a rapid and potent sensitizer in the printing industry.","10954995",40]
["1,6-hexanediol diacrylate","1,6-hexanediol diacrylate","C020355","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2014,"25231388","Severe bullous allergic contact dermatitis caused by glycidyl methacrylate and other acrylates.","25231388",40]
["1,6-hexanediol diacrylate","1,6-hexanediol diacrylate","C020355","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2015,"26028576","Erythema multiforme contact dermatitis after accidental exposure to acrylate-based printing inks.","26028576",40]
["1,6-hexanediol diacrylate","1,6-hexanediol diacrylate","C020355","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1981,"6458229","[Irritation and allergy to acrylates and methacrylates. - Part II: Polyfunctional acrylic monomers (author's transl)].","6458229",40]
["1,6-hexanediol diacrylate","1,6-hexanediol diacrylate","C020355","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1981,"7315737","Hexanediol diacrylate.","7315737",40]
["1,6-hexanediol diglycidyl ether","1,6-hexanediol diglycidyl ether","C414962","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2016,"26537833","Sensitization to reactive diluents and hardeners in epoxy resin systems. IVDK data 2002-2011. Part II: concomitant reactions.","26537833",40]
["1,6-hexanediol diglycidyl ether","1,6-hexanediol diglycidyl ether","C414962","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2016,"26538018","Sensitization to reactive diluents and hardeners in epoxy resin systems. IVDK data 2002-2011. Part I: reaction frequencies.","26538018",40]
["1,6-hexanediol diglycidyl ether","1,6-hexanediol diglycidyl ether","C414962","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"10875681","Dermal penetration and metabolism of five glycidyl ethers in human, rat and mouse skin.","10875681",40]
["1,7-bis(3,4-dihydroxyphenyl)hept-4-en-3-one oxime","1,7-bis(3,4-dihydroxyphenyl)hept-4-en-3-one oxime","C557715","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"21061471","Diarylheptanoid hirsutenoxime inhibits toll-like receptor 4-mediated NF-κB activation regulated by Akt pathway in keratinocytes.","21061471",40]
["1,7-bis(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one","1,7-bis(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one","C471106","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2016,"27564257","New therapy with ASC-J9® to suppress the prostatitis via altering the cytokine CCL2 signals.","27564257",40]
["1,7-bis(4-hydroxyphenyl)-4-N-phenylaminocarbonylhepta-1,6-dien-3,5-dione","1,7-bis(4-hydroxyphenyl)-4-N-phenylaminocarbonylhepta-1,6-dien-3,5-dione","C000589611","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"27038334","A novel chemically modified curcumin reduces inflammation-mediated connective tissue breakdown in a rat model of diabetes: periodontal and systemic effects.","27038334",40]
["1,7-dimethylxanthine","1,7-dimethylxanthine","C021183","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"2859173","Pharmacokinetics of paraxanthine, one of the primary metabolites of caffeine, in the rat.","2859173",40]
["1,7-dimethylxanthine","1,7-dimethylxanthine","C021183","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3371146","Caffeine disposition in the pregnant rabbit. II. Fetal distribution of caffeine and paraxanthine during chronic maternal caffeine administration.","3371146",40]
["1,7-dimethylxanthine","1,7-dimethylxanthine","C021183","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3612497","Caffeine and paraxanthine pharmacokinetics in the rabbit: concentration and product inhibition effects.","3612497",40]
["1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydroacridine","1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydroacridine","C122128","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26043757","Molecular perception of interactions between bis(7)tacrine and cystamine-tacrine dimer with cholinesterases as the promising proposed agents for the treatment of Alzheimer's disease.","26043757",40]
["1,8-diazabicyclo(5.4.0)undec-7-ene","1,8-diazabicyclo(5.4.0)undec-7-ene","C031033","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11587187","Improved preparation of amyloid-beta peptides using DBU as Nalpha-Fmoc deprotection reagent.","11587187",40]
["1,8-dihydroxy-10-(2-(4-methylphenyl)-1-oxoethyl)-9(10H)-anthracenone","1,8-dihydroxy-10-(2-(4-methylphenyl)-1-oxoethyl)-9(10H)-anthracenone","C423348","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2001,"11262091","Antipsoriatic anthrones with modulated redox properties. 5. Potent inhibition of human keratinocyte growth, induction of keratinocyte differentiation, and reduced membrane damage by novel 10-arylacetyl-1,8-dihydroxy-9(10H)-anthracenones.","11262091",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1347,B1347)","v":"1,8-dinitropyrene"},"1,8-dinitropyrene","C033310","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1347,K1347)","v":"Protein Binding"},"D011485","Protein Binding",1,1,1995,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1347,Q1347)","v":"7626273"},"Erythrocyte-mediated toxification of 1,8-dinitropyrene. II. Covalent bind to erythrocyte-proteins.","7626273",40]
["1,9-dimethylmethylene blue","1,9-dimethylmethylene blue","C016401","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28377303","The monoamine oxidase inhibition properties of selected structural analogues of methylene blue.","28377303",40]
["1,N(6)-ethenoadenine","1,N(6)-ethenoadenine","C004981","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10891085","Cisplatin adducts inhibit 1,N(6)-ethenoadenine repair by interacting with the human 3-methyladenine DNA glycosylase.","10891085",40]
["1,N(6)-ethenoadenine","1,N(6)-ethenoadenine","C004981","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11527427","Design and evaluation of a tryptophanless RecA protein with wild type activity.","11527427",40]
["1,N(6)-ethenoadenine","1,N(6)-ethenoadenine","C004981","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9425080","Specific interaction of wild-type and truncated mouse N-methylpurine-DNA glycosylase with ethenoadenine-containing DNA.","9425080",40]
["10-(2-(4-methoxyphenyl)-2-oxoethylidene)-10H-anthracen-9-one","10-(2-(4-methoxyphenyl)-2-oxoethylidene)-10H-anthracen-9-one","C550360","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19220018","10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.","19220018",40]
["10-(3-propionyloxysuccinimide)-2-(trifluoromethyl)phenothiazine","10-(3-propionyloxysuccinimide)-2-(trifluoromethyl)phenothiazine","C042522","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6547949","The synthesis and reaction of a specific affinity label for the hydrophobic drug-binding domains of calmodulin.","6547949",40]
["10-(6'-plastoquinonyl)decyltriphenylphosphonium","10-(6'-plastoquinonyl)decyltriphenylphosphonium","C532038","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2012,"22591624","In vivo immunoregulatory properties of the novel mitochondria-targeted antioxidant SkQ1.","22591624",40]
["10-(6'-plastoquinonyl)decyltriphenylphosphonium","10-(6'-plastoquinonyl)decyltriphenylphosphonium","C532038","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2012,"22591624","In vivo immunoregulatory properties of the novel mitochondria-targeted antioxidant SkQ1.","22591624",40]
["10-(6'-plastoquinonyl)decyltriphenylphosphonium","10-(6'-plastoquinonyl)decyltriphenylphosphonium","C532038","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2012,"22591624","In vivo immunoregulatory properties of the novel mitochondria-targeted antioxidant SkQ1.","22591624",40]
["10-(6'-plastoquinonyl)decyltriphenylphosphonium","10-(6'-plastoquinonyl)decyltriphenylphosphonium","C532038","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"18703059","Interrelations of mitochondrial fragmentation and cell death under ischemia/reoxygenation and UV-irradiation: protective effects of SkQ1, lithium ions and insulin.","18703059",40]
["10-(6'-plastoquinonyl)decyltriphenylphosphonium","10-(6'-plastoquinonyl)decyltriphenylphosphonium","C532038","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"28429222","Comparison of the Effects of Mitochondria-Targeted Antioxidant 10-(6'-Plastoquinonyl)Decyltriphenylphosphonium Bromide (SkQ1) and a Fragment of its Molecule Dodecyltriphenylphosphonium on Carrageenan-Induced Acute Inflammation in Mouse Model of Subcuteneous Air Pouch.","28429222",40]
["10-(cyclohexylamino)-12-((2-hydroxyethyl)amino)-15-oxa-14-azatetracyclohexadeca-1(16),2,4,6,9,11,13-heptaen-8-one","10-(cyclohexylamino)-12-((2-hydroxyethyl)amino)-15-oxa-14-azatetracyclohexadeca-1(16),2,4,6,9,11,13-heptaen-8-one","C559861","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21438571","Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4.","21438571",40]
["10,10'-dimethyl-9,9'-biacridinium","10,10'-dimethyl-9,9'-biacridinium","C033472","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1986,"2430396","Cellular reactivity of polymorphonuclear leukocytes in psoriasis and atopic dermatitis--measurement of lucigenin-dependent chemiluminescence.","2430396",40]
["10,10'-dimethyl-9,9'-biacridinium","10,10'-dimethyl-9,9'-biacridinium","C033472","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2811856","Vesicular uptake system for the cation lucigenin in the rat hepatocyte.","2811856",40]
["10,10'-dimethyl-9,9'-biacridinium","10,10'-dimethyl-9,9'-biacridinium","C033472","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"2853769","The mechanism of enzymically induced chemiluminescence reactions of lucigenin.","2853769",40]
["10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide","10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide","C004822","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3750374","Clinical pharmacokinetics of carbamazepine and its epoxy and hydroxy metabolites in humans after an overdose.","3750374",40]
["10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide","10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide","C004822","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8946662","Relationships between carbamazepine-diol, carbamazepine-epoxide, and carbamazepine total and free steady-state concentrations in epileptic patients: the influence of age, sex, and comedication.","8946662",40]
["10,11-dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide","10,11-dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide","C428744","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20578208","Binding of licarbazepine enantiomers to mouse and human plasma proteins.","20578208",40]
["10,11-dihydro-10-hydroxycarbamazepine","10,11-dihydro-10-hydroxycarbamazepine","C039775","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2076729","Protein binding of oxcarbazepine and its primary active metabolite, 10-hydroxycarbazepine, in patients with trigeminal neuralgia.","2076729",40]
["10,11-dihydro-10-hydroxycarbamazepine","10,11-dihydro-10-hydroxycarbamazepine","C039775","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6650125","Pharmacokinetics of 10-OH-carbazepine, the main metabolite of the antiepileptic oxcarbazepine, from serum and saliva concentrations.","6650125",40]
["10,11-dihydro-10-hydroxycarbamazepine","10,11-dihydro-10-hydroxycarbamazepine","C039775","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8992022","Pharmacokinetics of oxcarbazepine in the dog.","8992022",40]
["10,11-dihydroxy-N-n-propylnorapomorphine","10,11-dihydroxy-N-n-propylnorapomorphine","C425777","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12086672","betagamma Dimers mediate synergy of dopamine D2 and adenosine A2 receptor-stimulated PKA signaling and regulate ethanol consumption.","12086672",40]
["10,11-dihydroxy-N-n-propylnorapomorphine","10,11-dihydroxy-N-n-propylnorapomorphine","C425777","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2005,"15617728","Effects of long-term biogenic amine transporter blockade on receptor/G-protein coupling in rat brain.","15617728",40]
["10,11-methylenedioxycamptothecin","10,11-methylenedioxycamptothecin","C120496","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"25129757","Transdermal delivery of 10,11-methylenedioxycamptothecin by hyaluronic acid based nanoemulsion for inhibition of keloid fibroblast.","25129757",40]
["10074-G5","10074-G5","C534883","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2008,"19022175","Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules.","19022175",40]
["10074-G5","10074-G5","C534883","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"20801893","In vitro cytotoxicity and in vivo efficacy, pharmacokinetics, and metabolism of 10074-G5, a novel small-molecule inhibitor of c-Myc/Max dimerization.","20801893",40]
["10074-G5","10074-G5","C534883","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23177256","Pharmacophore identification of c-Myc inhibitor 10074-G5.","23177256",40]
["10074-G5","10074-G5","C534883","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23801058","Disruption of Myc-Max heterodimerization with improved cell-penetrating analogs of the small molecule 10074-G5.","23801058",40]
["10-acetoxy-8,9-epoxythymol isobutyrate","10-acetoxy-8,9-epoxythymol isobutyrate","C057029","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1988,"2970374","[Allergic contact dermatitis caused by Asteraceae. Identification of an 8,9-epoxythymol-diester as the contact allergen of Arnica sachalinensis].","2970374",40]
["10-acetoxy-8,9-epoxythymol isobutyrate","10-acetoxy-8,9-epoxythymol isobutyrate","C057029","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"2970374","[Allergic contact dermatitis caused by Asteraceae. Identification of an 8,9-epoxythymol-diester as the contact allergen of Arnica sachalinensis].","2970374",40]
["10-carboxydecyl-2-chloroethylsulfide","10-carboxydecyl-2-chloroethylsulfide","C099676","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8644110","In vivo and in vitro toxicity of newly synthesized monofunctional sulfur mustard derivatives.","8644110",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,1999,"10392438","[Effectiveness of cycloferon in treating virus-associated inflammatory gynecologic diseases].","10392438",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2014,"25975104","[Cycloferon therapy of chronic gastroduodenitis in children].","25975104",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"2417573","Interaction of sodium salt of 9-oxo-10-acridineacetic acid (CMA) and its analogs with serum albumin. A model for study on binding of the interferon inducer with receptor.","2417573",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"16786663","[Immunocorrective effect of cycloferon and thymogen in patients with uterine cancer].","16786663",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1991,"1805690","[The role of immunocytes in the production of interferon in response to its induction by aromatic hydrocarbons].","1805690",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2012,"22741199","[Evaluation of safety and pharmacotherapeutic efficacy of cycloferon in treatment of Astrakhan rickettsial fever].","22741199",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2012,"22993934","[Cycloferon use in complex therapy of children with salmonellosis and yersiniosis infection].","22993934",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22997921","[Efficacy of combined immunocorrection in the treatment of chronic viral hepatitis C].","22997921",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"24003487","[Efficiency of cycloferon against slow viral infection caused by SV-40 in monkeys and man].","24003487",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2013,"24400389","[Evaluation of the effectiveness of immunomodulating therapy in children with chronic gastroduodenitis].","24400389",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1986,"3081999","Production of interferon-beta by murine T-cell lines induced by 10-carboxymethyl-9-acridanone.","3081999",40]
["10-carboxymethyl-9-acridanone","10-carboxymethyl-9-acridanone","C026430","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"3878695","Competition of sodium salt of 9-oxo-10-acridineacetic acid with analogs during induction of interferon in the mouse bone marrow-derived macrophages.","3878695",40]
["10-deazaaminopterin","10-deazaaminopterin","C017178","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1983,"6825121","Phase I trial of 10-deaza-aminopterin in patients with advanced cancer.","6825121",40]
["10-decarbamoylmitomycin C","10-decarbamoylmitomycin C","C067795","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12183457","Differential activation of p53 by the various adducts of mitomycin C.","12183457",40]
["10-decarbamoylmitomycin C","10-decarbamoylmitomycin C","C067795","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2015,"25565400","Decarbamoyl mitomycin C (DMC) activates p53-independent ataxia telangiectasia and rad3 related protein (ATR) chromatin eviction.","25565400",40]
["10-decarboxymethylaclacinomycin T","10-decarboxymethylaclacinomycin T","C478393","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12878604","Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism.","12878604",40]
["10-ethyldithranol","10-ethyldithranol","C053912","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1987,"3653461","Dithranol: further investigations on the structure-activity-relationship. The new series of the 10-mono-alkyldithranol derivatives.","3653461",40]
["10-formyl-5,8-dideazafolate","10-formyl-5,8-dideazafolate","C092738","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14500878","On the structural and functional modularity of glycinamide ribonucleotide formyltransferases.","14500878",40]
["10-formylmethylflavin","10-formylmethylflavin","C115829","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25000466","Formation of a flavin-linked peptide.","25000466",40]
["10-hydroxy-11,12-epoxyeicosa-5,8,14-trienoic acid","10-hydroxy-11,12-epoxyeicosa-5,8,14-trienoic acid","C022948","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10553878","Stereoselective actions of hepoxilins A3 and B3 and their cyclopropane analogs (HxdeltaA3 and HxdeltaB3) on bradykinin and PAF-evoked potentiation of vascular leakage in rat skin.","10553878",40]
["10-hydroxy-11,12-epoxyeicosa-5,8,14-trienoic acid","10-hydroxy-11,12-epoxyeicosa-5,8,14-trienoic acid","C022948","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"9131155","Epimer-specific actions of hepoxilins A3 and B3 on PAF- and bradykinin-evoked vascular permeability in the rat skin in vivo.","9131155",40]
["10-hydroxy-12-octadecenoic acid","10-hydroxy-12-octadecenoic acid","C040430","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2017,"28438083","Supplemental feeding of a gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, alleviates spontaneous atopic dermatitis and modulates intestinal microbiota in NC/nga mice.","28438083",40]
["10-hydroxy-2-decenoic acid","10-hydroxy-2-decenoic acid","C055543","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"28793915","The functional property of royal jelly 10-hydroxy-2-decenoic acid as a melanogenesis inhibitor.","28793915",40]
["10-hydroxycamptothecin","10-hydroxycamptothecin","C028098","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2004,"15225428","[Anti-tumor effects of 10-hydroxycamptothecinc-treated DC-Hepa1-6 fusion vaccines].","15225428",40]
["10-hydroxycamptothecin","10-hydroxycamptothecin","C028098","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17896941","Hydroxycamptothecin deactivation rates and binding to model membranes and HSA determined by fluorescence spectra analysis.","17896941",40]
["10-hydroxycamptothecin","10-hydroxycamptothecin","C028098","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22160573","Interaction of human serum albumin with 10-hydroxycamptothecin: spectroscopic and molecular modeling studies.","22160573",40]
["10-hydroxynortriptyline","10-hydroxynortriptyline","C013567","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1571065","Comparative cardiotoxicity of nortriptyline and its isomeric 10-hydroxymetabolites.","1571065",40]
["10-hydroxynortriptyline","10-hydroxynortriptyline","C013567","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17944232","[Influence of ORM1 polymorphism on serum concentration of free nortriptyline].","17944232",40]
["10-hydroxynortriptyline","10-hydroxynortriptyline","C013567","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1852713","Stereoselective efflux of (E)-10-hydroxynortriptyline enantiomers from the cerebrospinal fluid of depressed patients.","1852713",40]
["10-hydroxynortriptyline","10-hydroxynortriptyline","C013567","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"6808544","Antidepressive effect and pharmacokinetics of amitriptyline with consideration of unbound drug and 10-hydroxynortriptyline plasma levels.","6808544",40]
["10-hydroxywarfarin","10-hydroxywarfarin","C065719","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24297869","A cellular system for quantitation of vitamin K cycle activity: structure-activity effects on vitamin K antagonism by warfarin metabolites.","24297869",40]
["10-hydroxyyohimbine","10-hydroxyyohimbine","C081037","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8097957","Alpha 2-adrenoceptor antagonist potencies of two hydroxylated metabolites of yohimbine.","8097957",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1411,B1411)","v":"10-isobutyryl dithranol"},"10-isobutyryl dithranol","C050406","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1411,K1411)","v":"Skin"},"D012867","Skin",0,1,1986,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1411,Q1411)","v":"3757176"},"Tumor-producing and skin-irritating activity of dithranol (anthralin) and its 10-acyl analogues in SENCAR mice.","3757176",40]
["10-N-(bromoacetyl)amino-1-decylglucopyranoside","10-N-(bromoacetyl)amino-1-decylglucopyranoside","C044848","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12023968","The role of constant region carbohydrate in the assembly and secretion of human IgD and IgA1.","12023968",40]
["10-nitro-9,12-octadecadienoic acid","10-nitro-9,12-octadecadienoic acid","C501855","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19534727","Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions.","19534727",40]
["10-nitrofolic acid","10-nitrofolic acid","C468779","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12372420","Nitration and chlorination of folic acid by peroxynitrite and hypochlorous acid, and the selective binding of 10-nitro-folate to folate receptor beta.","12372420",40]
["10-nitro-oleic acid","10-nitro-oleic acid","C521487","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2014,"24140437","Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid.","24140437",40]
["1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine","1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine","C026613","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1986,"3800968","PAF-acether (1-O-hexadecyl/octadecyl-2-acetyl-sn-glycero-3-phosphocholine)-induced fibrinogen binding to platelets depends on metabolic energy.","3800968",40]
["1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine","1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine","C026613","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1984,"6581831","Inflammatory characteristics of platelet activating factor (PAF-acether) in human skin.","6581831",40]
["10-oxahexadecanolide","10-oxahexadecanolide","C571586","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21801793","Fragrance material review on 10-oxahexadecanolide.","21801793",40]
["10-propargyl-10-deazaaminopterin","10-propargyl-10-deazaaminopterin","C418863","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2014,"24452280","Clinical remission of primary aggressive CD8+ cutaneous T-cell lymphoma after pralatrexate infusion.","24452280",40]
["10-propargyl-10-deazaaminopterin","10-propargyl-10-deazaaminopterin","C418863","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2008,"18280345","CD4+ CD56+ hematodermic/plasmacytoid dendritic cell tumor with response to pralatrexate.","18280345",40]
["10-propargyl-10-deazaaminopterin","10-propargyl-10-deazaaminopterin","C418863","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2012,"22394596","Identification of an active, well-tolerated dose of pralatrexate in patients with relapsed or refractory cutaneous T-cell lymphoma.","22394596",40]
["10-propionyl dithranol","10-propionyl dithranol","C038463","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1983,"6192640","Irritation and staining by dithranol (anthralin) and related compounds. III. Cumulative irritancy and staining during repeated chamber testing.","6192640",40]
["10-valeryl dithranol","10-valeryl dithranol","C050405","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1986,"3757176","Tumor-producing and skin-irritating activity of dithranol (anthralin) and its 10-acyl analogues in SENCAR mice.","3757176",40]
["11-((1-(3-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-1,2,3-triazol-4-yl)methoxy)-N-propylnoraporphine","11-((1-(3-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-1,2,3-triazol-4-yl)methoxy)-N-propylnoraporphine","C559079","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21334902","Further SAR study on 11-O-substituted aporphine analogues: identification of highly potent dopamine D3 receptor ligands.","21334902",40]
["11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene","11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene","C561234","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25600203","Metabolism and Disposition of Pacritinib (SB1518), an Orally Active Janus Kinase 2 Inhibitor in Preclinical Species and Humans.","25600203",40]
["11-(3-(4-((4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine","11-(3-(4-((4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine","C559080","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21334902","Further SAR study on 11-O-substituted aporphine analogues: identification of highly potent dopamine D3 receptor ligands.","21334902",40]
["11-(dansylamino)undecanoic acid","11-(dansylamino)undecanoic acid","C054400","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10606528","Binding of recombinant rat liver fatty acid-binding protein to small anionic phospholipid vesicles results in ligand release: a model for interfacial binding and fatty acid targeting.","10606528",40]
["11-(dansylamino)undecanoic acid","11-(dansylamino)undecanoic acid","C054400","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15374624","A native 13-kDa fatty acid binding protein from the liver fluke Fasciola hepatica.","15374624",40]
["11-(dansylamino)undecanoic acid","11-(dansylamino)undecanoic acid","C054400","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21997768","A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin.","21997768",40]
["11-(dansylamino)undecanoic acid","11-(dansylamino)undecanoic acid","C054400","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22971149","Characterizing the fatty acid binding site in the cavity of potassium channel KcsA.","22971149",40]
["11-(dansylamino)undecanoic acid","11-(dansylamino)undecanoic acid","C054400","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3426548","Studies on fatty acid-binding proteins. The binding properties of rat liver fatty acid-binding protein.","3426548",40]
["11,11-azi-stearic acid","11,11-azi-stearic acid","C103296","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8732774","Irreversible inhibition of hepatic fatty acid salt uptake by photoaffinity labeling with 11, 11-azistearate.","8732774",40]
["11,12-dihydroxyeicosatrienoic acid","11,12-dihydroxyeicosatrienoic acid","C410128","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16904368","Inhibition of ATP binding to the carboxyl terminus of Kir6.2 by epoxyeicosatrienoic acids.","16904368",40]
["11,12-epoxy-5,8,14-eicosatrienoic acid","11,12-epoxy-5,8,14-eicosatrienoic acid","C046783","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16904368","Inhibition of ATP binding to the carboxyl terminus of Kir6.2 by epoxyeicosatrienoic acids.","16904368",40]
["11,12-epoxy-5,8,14-eicosatrienoic acid","11,12-epoxy-5,8,14-eicosatrienoic acid","C046783","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25139746","Nitric oxide and protein kinase G act on TRPC1 to inhibit 11,12-EET-induced vascular relaxation.","25139746",40]
["11,12-epoxy-5,8,14-eicosatrienoic acid","11,12-epoxy-5,8,14-eicosatrienoic acid","C046783","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"27416746","CYP2J2 and its metabolites (epoxyeicosatrienoic acids) attenuate cardiac hypertrophy by activating AMPKα2 and enhancing nuclear translocation of Akt1.","27416746",40]
["11,12-epoxyeicosatrienoic acid methyl ester","11,12-epoxyeicosatrienoic acid methyl ester","C515338","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16904368","Inhibition of ATP binding to the carboxyl terminus of Kir6.2 by epoxyeicosatrienoic acids.","16904368",40]
["11,13-dihydroxy-14-octadecaenoic acid","11,13-dihydroxy-14-octadecaenoic acid","C067685","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1991,"1847965","Identification of 11,13-dihydroxy-14-octadecaenoic acid as a circulating Na+/K(+)-ATPase inhibitor.","1847965",40]
["11,14,17-eicosatrienoic acid","11,14,17-eicosatrienoic acid","C034152","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2010,"20514327","Skin aging and photoaging alter fatty acids composition, including 11,14,17-eicosatrienoic acid, in the epidermis of human skin.","20514327",40]
["11,14,17-eicosatrienoic acid","11,14,17-eicosatrienoic acid","C034152","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20514317","Prevention of UV-induced skin damages by 11,14,17-eicosatrienoic acid in hairless mice in vivo.","20514317",40]
["11,15-dioxo-9-hydroxy-2,3,4,5-tetranorprostan-1,20-dioic acid","11,15-dioxo-9-hydroxy-2,3,4,5-tetranorprostan-1,20-dioic acid","C527346","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,2011,"21721371","Serum tryptase level is a better predictor of systemic side effects than prostaglandin D2 metabolites during venom immunotherapy in children.","21721371",40]
["11,17-dihydroxy-6-methyl-17-(1-propynyl)androsta-1,4,6-triene-3-one","11,17-dihydroxy-6-methyl-17-(1-propynyl)androsta-1,4,6-triene-3-one","C049154","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"7956914","Effects of selective type I and II adrenal steroid agonists on immune cell distribution.","7956914",40]
["111In-DOTA-1-Nal(3)-octreotide","111In-DOTA-1-Nal(3)-octreotide","C487387","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12937948","DOTA-NOC, a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5 for labelling with various radiometals.","12937948",40]
["11-aminoundecyltrimethoxysilane","11-aminoundecyltrimethoxysilane","C000597752","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,2014,"24281326","Development of a new parallelized, optical biosensor platform for label-free detection of autoimmunity-related antibodies.","24281326",40]
["11-dehydro-thromboxane B2","11-dehydro-thromboxane B2","C049235","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,1997,"9414142","Urinary excretion of leukotriene E4 and 11-dehydrothromboxane B2 in patients with spontaneous asthma attacks.","9414142",40]
["11-deoxyprostaglandin E2-1-alcohol","11-deoxyprostaglandin E2-1-alcohol","C067521","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1847772","Characterisation of PGE2 receptors mediating increased vascular permeability in inflammation.","1847772",40]
["11-dimethylaminopropoxy-4-methylbenzofuro(3,2-g)coumarin","11-dimethylaminopropoxy-4-methylbenzofuro(3,2-g)coumarin","C400072","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10543884","New tetracyclic analogues of photochemotherapeutic drugs 5-MOP and 8-MOP: synthesis, DNA interaction, and antiproliferative activity.","10543884",40]
["11-glutathionylhepoxilin A3","11-glutathionylhepoxilin A3","C061163","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10553878","Stereoselective actions of hepoxilins A3 and B3 and their cyclopropane analogs (HxdeltaA3 and HxdeltaB3) on bradykinin and PAF-evoked potentiation of vascular leakage in rat skin.","10553878",40]
["11-hexadecenal","11-hexadecenal","C061128","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26923548","A single aldehyde group can serve as a structural element for recognition by transmembrane protein CD36.","26923548",40]
["11-hexadecenyl trifluoromethyl ketone","11-hexadecenyl trifluoromethyl ketone","C480312","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28070757","RNAi-Induced Electrophysiological and Behavioral Changes Reveal two Pheromone Binding Proteins of Helicoverpa armigera Involved in the Perception of the Main Sex Pheromone Component Z11-16:Ald.","28070757",40]
["11-hexadecenyl trifluoromethyl ketone","11-hexadecenyl trifluoromethyl ketone","C480312","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2018,"29447443","Inhibitor Bound Dengue NS2B-NS3pro Reveals Multiple Dynamic Binding Modes.","29447443",40]
["11-hydroxy-delta(9)-tetrahydrocannabinol","11-hydroxy-delta(9)-tetrahydrocannabinol","C001427","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1990,"2159920","Age-related suppression of murine lymphoid cell blastogenesis by marijuana components.","2159920",40]
["11-hydroxy-delta(9)-tetrahydrocannabinol","11-hydroxy-delta(9)-tetrahydrocannabinol","C001427","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"3003204","The effect of delta-9-tetrahydrocannabinol and 11-hydroxy-delta-9-tetrahydrocannabinol on T-lymphocyte and B-lymphocyte mitogen responses.","3003204",40]
["11-hydroxy-N-(n-propyl)noraporphine","11-hydroxy-N-(n-propyl)noraporphine","C008081","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18585036","Synthesis and binding studies of 2-O- and 11-O-substituted N-alkylnoraporphines.","18585036",40]
["11-hydroxyyohimbine","11-hydroxyyohimbine","C081038","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8097957","Alpha 2-adrenoceptor antagonist potencies of two hydroxylated metabolites of yohimbine.","8097957",40]
["11-keto-boswellic acid","11-keto-boswellic acid","C447943","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19648270","Identification of human cathepsin G as a functional target of boswellic acids from the anti-inflammatory remedy frankincense.","19648270",40]
["11-ketodexamethasone","11-ketodexamethasone","C484907","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15062542","The 11-ketosteroid 11-ketodexamethasone is a glucocorticoid receptor agonist.","15062542",40]
["11-mercaptoundecanoic acid","11-mercaptoundecanoic acid","C505222","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19908744","Fabrication of nano scaled protein monolayer consisting of cytochrome c on self-assembled 11-MUA layer for bioelectronic device.","19908744",40]
["11-mercaptoundecanoic acid","11-mercaptoundecanoic acid","C505222","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26369114","Fatigue Test of Cytochrome C Self-Assembled on a 11-MUA Layer Based on Electrochemical Analysis for Bioelectronic Device.","26369114",40]
["11-methoxygelselegine","11-methoxygelselegine","C576442","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22579843","Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans.","22579843",40]
["11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid","11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid","C016780","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11955826","Partition coefficient, blood to plasma ratio, protein binding and short-term stability of 11-nor-Delta(9)-carboxy tetrahydrocannabinol glucuronide.","11955826",40]
["11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid","11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid","C016780","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12505464","Interpretations of the TDxFLx calibration data of the abused drugs.","12505464",40]
["11-octadecenoic acid","11-octadecenoic acid","C050413","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,2014,"25119335","Elaidic, vaccenic, and rumenic acid status during pregnancy: association with maternal plasmatic LC-PUFAs and atopic manifestations in infants.","25119335",40]
["11-O-protocatechuoyl-tri-O-methylnorbergenin","11-O-protocatechuoyl-tri-O-methylnorbergenin","C000589836","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"24268551","Synthesis, antioxidant capacity, and structure-activity relationships of tri-O-methylnorbergenin analogues on tyrosinase inhibition.","24268551",40]
["11-oxahexadecanolide","11-oxahexadecanolide","C571587","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21801789","Fragrance material review on 11-oxahexadecanolide.","21801789",40]
["11-phenylundeca-5,9-dienoic acid","11-phenylundeca-5,9-dienoic acid","C000604944","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25968900","11-Phenylundeca-5Z,9Z-dienoic Acid: Stereoselective Synthesis and Dual Topoisomerase I/IIα Inhibition.","25968900",40]
["12,13-bisepieupalmerin","12,13-bisepieupalmerin","C043525","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8102324","Diterpenoids from Caribbean gorgonians act as noncompetitive inhibitors of the nicotinic acetylcholine receptor.","8102324",40]
["12-acetoxyhawtriwaic acid lactone","12-acetoxyhawtriwaic acid lactone","C513234","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2008,"18670081","Topically applied diterpenoids from Egletes viscosa (Asteraceae) attenuate the dermal inflammation in mouse ear induced by tetradecanoylphorbol 13-acetate- and oxazolone.","18670081",40]
["12-aminododecanoic acid","12-aminododecanoic acid","C046049","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2016,"26653407","Systematic evaluation of self-adjuvanting lipopeptide nano-vaccine platforms for the induction of potent CD8(+) T-cell responses.","26653407",40]
["12-aminododecanoic acid","12-aminododecanoic acid","C046049","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28045391","Crystal structure of a putrescine aminotransferase from Pseudomonas sp. strain AAC.","28045391",40]
["12-deoxyphorbolphenylacetate","12-deoxyphorbolphenylacetate","C029704","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1995,"7870033","Differential regulation by anti-tumor-promoting 12-deoxyphorbol-13-phenylacetate reveals distinct roles of the classical and novel protein kinase C isozymes in biological responses of primary mouse keratinocytes.","7870033",40]
["12-deoxyphorbolphenylacetate-20-acetate","12-deoxyphorbolphenylacetate-20-acetate","C029705","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"7929699","12-Deoxyphorbol-13-O-phenylacetate 20 acetate [an agonist of protein kinase C beta 1 (PKC beta 1)] induces DNA synthesis, interleukin-2 (IL-2) production, IL-2 receptor alpha-chain (CD25) and beta-chain (CD122) expression, and translocation of PKC beta isozyme in human peripheral blood lymphocytes: evidence for a role of PKC beta 1 in human T cell activation.","7929699",40]
["12-doxylstearate methyl ester","12-doxylstearate methyl ester","C024283","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"6245076","Mobility of apolar lipids of reconstituted low density lipoprotein as monitored by electron spin resonance spectroscopy.","6245076",40]
["12-doxylstearic acid","12-doxylstearic acid","C037404","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6298212","Self-aggregation, a new property of cardiac fatty acid-binding protein. Predictable influence on energy production in the heart.","6298212",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1475,B1475)","v":"12-formyl-5,6-dihydro-3,9-dihydroxy-6-propylindolo(2,1-a)isoquinoline"},"12-formyl-5,6-dihydro-3,9-dihydroxy-6-propylindolo(2,1-a)isoquinoline","C109176","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1475,K1475)","v":"Protein Binding"},"D011485","Protein Binding",1,1,1997,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1475,Q1475)","v":"9357519"},"Inhibition of tubulin polymerization by 5,6-dihydroindolo[2,1-alpha]isoquinoline derivatives.","9357519",40]
["12-hydroxy stearic acid","12-hydroxy stearic acid","C539357","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2009,"19958732","Allergic contact dermatitis from 12-hydroxystearic Acid and hydrogenated castor oil.","19958732",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1992,"1323467","Defect of epidermal 12(S)-hydroxyeicosatetraenoic acid receptors in psoriasis.","1323467",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1992,"1384866","Differential increase in 12-HETE release and CD29/CD49f expression of platelets from normal donors and from patients with atopic dermatitis by Staphylococcus aureus.","1384866",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1984,"6331487","Levels of arachidonic acid and its metabolites in the skin in human allergic and irritant contact dermatitis.","6331487",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1982,"6187199","Leukotrienes and lipoxygenase factors: mediators and modulators of the allergic reaction.","6187199",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1980,"6251366","Mediators of immediate hypersensitivity derived from arachidonic acid.","6251366",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1999,"10073141","10-alpha-Aminoacyl-9(10H)-anthracenones: inhibition of 12(S)-HETE biosynthesis and HaCaT cell growth.","10073141",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1992,"1323467","Defect of epidermal 12(S)-hydroxyeicosatetraenoic acid receptors in psoriasis.","1323467",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1991,"1789988","Effect of ciclosporin on epidermal 12(S)-hydroxyeicosatetraenoic acid binding sites.","1789988",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1990,"2175266","Regulation of 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE) binding sites on human epidermal cells by interferon-gamma.","2175266",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1997,"9254882","Effect of 12-O-tetradecanoylphorbol-13-acetate on inhibition of expression of keratin 1 mRNA in mouse keratinocytes mimicked by 12(S)-hydroxyeicosatetraenoic acid.","9254882",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1994,"7825861","Metabolism of leukotriene B4 (LTB4) and 12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HETE) in human keratinocytes.","7825861",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1993,"8394769","Characterization of high-affinity 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE) binding sites on normal human keratinocytes.","8394769",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1996,"8759634","Antipsoriatic anthrones with modulated redox properties. 3. 10-thio-substituted 1,8-dihydroxy-9(10H)-anthracenones as inhibitors of keratinocyte growth, 5-lipoxygenase, and the formation of 12(S)-HETE in mouse epidermis.","8759634",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1999,"10375396","The 650-kDa 12(S)-hydroxyeicosatetraenoic acid binding complex: occurrence in human platelets, identification of hsp90 as a constituent, and binding properties of its 50-kDa subunit.","10375396",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10585225","Study of binding of 12(S)-hydroxy-5(Z),8(Z),10(E), 14(Z)-eicosatetraenoic acid to bovine serum albumin using dynamic surface tension measurements.","10585225",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10823935","A 12(S)-hydroxyeicosatetraenoic acid receptor interacts with steroid receptor coactivator-1.","10823935",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11786549","The oxidized lipid and lipoxygenase product 12(S)-hydroxyeicosatetraenoic acid induces hypertrophy and fibronectin transcription in vascular smooth muscle cells via p38 MAPK and cAMP response element-binding protein activation. Mediation of angiotensin II effects.","11786549",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21712392","Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetraenoic acid.","21712392",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"10940814","Assessment of toxic potential of industrial chemicals using a cultured human bioartificial skin model: production of interleukin 1alpha and hydroxyeicosatetraenoic acids.","10940814",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1789988","Effect of ciclosporin on epidermal 12(S)-hydroxyeicosatetraenoic acid binding sites.","1789988",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2560200","SC-41930 inhibits neutrophil infiltration of the cavine dermis induced by 12(R)-hydroxyeicosatetraenoic acid.","2560200",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1985,"3010613","Cutaneous responses to lipoxygenase products of arachidonic acid.","3010613",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1987,"3027188","Effects of chronic intracutaneous administration of arachidonic acid and its metabolites. Induction of leukocytoclastic vasculitis by leukotriene B4 and 12-hydroxyeicosatetraenoic acid and its prevention by prostaglandin E2.","3027188",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1985,"3998504","Cutaneous responses to 12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HETE).","3998504",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1981,"6274465","The inflammatory effects of hydroperoxy and hydroxy acid products of arachidonate lipoxygenase in rabbit skin.","6274465",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1995,"7601505","Antiinflammatory effects of second-generation leukotriene B4 receptor antagonist, SC-53228: impact upon leukotriene B4- and 12(R)-HETE-mediated events.","7601505",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1997,"9199895","Effects of reactive oxygen species on the biosynthesis of 12 (S)-hydroxyeicosatetraenoic acid in mouse epidermal homogenate.","9199895",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1992,"1727629","Beta-oxidation of 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid by MOLT-4 lymphocytes.","1727629",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"2996948","Lipoxygenase pathways of macrophages.","2996948",40]
["12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6804096","Regulation of T-lymphocyte mitogenesis by the leukocyte product 15-hydroxy-eicosatetraenoic acid (15-HETE).","6804096",40]
["12-hydroxy-5,8,10-heptadecatrienoic acid","12-hydroxy-5,8,10-heptadecatrienoic acid","C008033","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2012,"22391335","12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity.","22391335",40]
["12-hydroxy-5,8,10-heptadecatrienoic acid","12-hydroxy-5,8,10-heptadecatrienoic acid","C008033","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2014,"24821912","12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor.","24821912",40]
["12-hydroxy-5,8,10-heptadecatrienoic acid","12-hydroxy-5,8,10-heptadecatrienoic acid","C008033","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2014,"24890114","Time heals all wounds--but 12-HHT is faster.","24890114",40]
["12-hydroxy-5,8,10-heptadecatrienoic acid","12-hydroxy-5,8,10-heptadecatrienoic acid","C008033","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2016,"26896822","The leukotriene B4 receptor BLT2 protects barrier function via actin polymerization with phosphorylation of myosin phosphatase target subunit 1 in human keratinocytes.","26896822",40]
["12-hydroxy-5,8,10-heptadecatrienoic acid","12-hydroxy-5,8,10-heptadecatrienoic acid","C008033","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"26571566","[Identification of the old and new lipid mediator, 12-HHT and the role in skin wound healing].","26571566",40]
["12-hydroxy-5,8,14-eicosatrienoic acid","12-hydroxy-5,8,14-eicosatrienoic acid","C067514","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1995,"7798640","Enhancement of delayed hypersensitivity inflammatory reactions in guinea pig skin by 12(R)-hydroxy-5,8,14-eicosatrienoic acid.","7798640",40]
["12-hydroxynevirapine sulfate","12-hydroxynevirapine sulfate","C000593863","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"18729332","Demonstration of the metabolic pathway responsible for nevirapine-induced skin rash.","18729332",40]
["12-hydroxyscabrolide A","12-hydroxyscabrolide A","C581249","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2013,"23200246","Anti-inflammatory norditerpenoids from the soft coral Sinularia maxima.","23200246",40]
["12-methylbenzanthracene","12-methylbenzanthracene","C021220","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1996,"8931739","Effects of methyl substitutions on benz[a]anthracene derivatives-induced immunosuppression.","8931739",40]
["12-nitrofolic acid","12-nitrofolic acid","C468780","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12372420","Nitration and chlorination of folic acid by peroxynitrite and hypochlorous acid, and the selective binding of 10-nitro-folate to folate receptor beta.","12372420",40]
["12-O-hexadecanoyl-4-deoxy-4 alpha-16-hydroxyphorbol-13-acetate","12-O-hexadecanoyl-4-deoxy-4 alpha-16-hydroxyphorbol-13-acetate","C028115","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1980,"7451556","Relationship between ornithine decarboxylase-inducing activity and configuration at C-4 in phorbol ester derivatives.","7451556",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1991,"1710462","TGF-beta 1 and skin carcinogenesis: antiproliferative effect in vitro and TGF-beta 1 mRNA expression during epidermal hyperproliferation and multistage tumorigenesis.","1710462",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21042803","Green tea prevents down-regulation of gap junction intercellular communication in human keratinocytes treated with PMA.","21042803",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16101150","12-O-retinoylphorbol-13-acetate (RPA) behaves like a retinoid-derivative in binding to retinol-binding-protein: a correlation with its specific action as an incomplete tumor promoter?","16101150",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2005,"16101150","12-O-retinoylphorbol-13-acetate (RPA) behaves like a retinoid-derivative in binding to retinol-binding-protein: a correlation with its specific action as an incomplete tumor promoter?","16101150",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1710462","TGF-beta 1 and skin carcinogenesis: antiproliferative effect in vitro and TGF-beta 1 mRNA expression during epidermal hyperproliferation and multistage tumorigenesis.","1710462",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1987,"3117560","Tumor-promoting phorbol esters cause a stable reduction of dermal collagen in mouse skin.","3117560",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1988,"3365842","Differential effects of phorbol esters on c-fos and c-myc and ornithine decarboxylase gene expression in mouse skin in vivo.","3365842",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1984,"6435122","Suppression of the first stage of phorbol 12-tetradecanoate 13-acetate-effected tumor promotion in mouse skin by nontoxic inhibition of DNA synthesis.","6435122",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1983,"6863986","Growth stimulation and tumor promotion in skin.","6863986",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1982,"7077157","Preparation of retinoic acid esters of phorbol derivatives.","7077157",40]
["12-O-retinoylphorbol-13-acetate","12-O-retinoylphorbol-13-acetate","C032974","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1994,"7528111","Effects of complete and incomplete tumor promoters on hair growth, angiogenesis, and tenascin expression in the skin of NMRI mice.","7528111",40]
["12-O-tetradeca-2,4,6,8-tetranoylphorbol-13-acetate","12-O-tetradeca-2,4,6,8-tetranoylphorbol-13-acetate","C032975","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1992,"1352313","The effects of interferon-beta on phorbol ester or calcium ionophore-induced intercellular adhesion molecule-I expression in epidermal carcinoma cells.","1352313",40]
["12-O-tetradeca-2,4,6,8-tetranoylphorbol-13-acetate","12-O-tetradeca-2,4,6,8-tetranoylphorbol-13-acetate","C032975","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2004,"15254728","Alpha 2-HS glycoprotein (fetuin-A) modulates murine skin tumorigenesis.","15254728",40]
["12-O-tetradeca-2,4,6,8-tetranoylphorbol-13-acetate","12-O-tetradeca-2,4,6,8-tetranoylphorbol-13-acetate","C032975","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8993955","Enhancing effect of ultraviolet A on ornithine decarboxylase induction and dermatitis evoked by 12-o-tetradecanoylphorbol-13-acetate and its inhibition by curcumin in mouse skin.","8993955",40]
["12-oxahexadecanolide","12-oxahexadecanolide","C571588","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21801790","Fragrance material review on 12-oxahexadecanolide.","21801790",40]
["12-oxophytodienoic acid","12-oxophytodienoic acid","C025999","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17113611","Preparative enzymatic solid phase synthesis of cis(+)-12-oxo-phytodienoic acid - physical interaction of AOS and AOC is not necessary.","17113611",40]
["12-oxophytodienoic acid","12-oxophytodienoic acid","C025999","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"26873978","Regulation of Arabidopsis thaliana seed dormancy and germination by 12-oxo-phytodienoic acid.","26873978",40]
["13,14-dihydro-15-ketoprostaglandin D2","13,14-dihydro-15-ketoprostaglandin D2","C034832","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2012,"22206772","PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis.","22206772",40]
["13,14-dihydro-15-ketoprostaglandin E1","13,14-dihydro-15-ketoprostaglandin E1","C036808","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1997,"9115911","In vivo formation of prostaglandin E1 and prostaglandin E2 in atopic dermatitis.","9115911",40]
["13,14-dihydroprostaglandin E2","13,14-dihydroprostaglandin E2","C025395","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1979,"398987","The use of immobilized ligands and [125I]protein a for immunoassays of thromboxane B2, prostaglandin D2, 13,14-dihydro-prostaglandin E2, 5,6-dihydro-prostaglandin I2, 6-keto-prostaglandin F1 alpha, 15-hydroxy-9 alpha, 11 alpha(epoxymethano)prosta-5,13-dienoic acid and 15-hydroxy-11 alpha,9 alpha(epoxymethano)prosta-5,13-dienoic acid.","398987",40]
["13,14-dihydroretinoic acid","13,14-dihydroretinoic acid","C503916","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26030625","9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice.","26030625",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1539,B1539)","v":"13,14-epoxyabietic acid"},"13,14-epoxyabietic acid","C104668","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1539,K1539)","v":"Dermatitis, Allergic Contact"},"D017449","Dermatitis, Allergic Contact",0,2,1994,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1539,Q1539)","v":"9868506"},"Allergenic components in modified and unmodified rosin. Chemical characterization and studies of allergenic activity.","9868506",40]
["13,14-epoxyabietic acid","13,14-epoxyabietic acid","C104668","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1996,"8957638","Isolated colophony allergens as screening substances for contact allergy.","8957638",40]
["13,15-O-bidesmethylascomycin","13,15-O-bidesmethylascomycin","C084050","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1993,"7693638","Enzymatic synthesis and immunosuppressive activity of novel desmethylated immunomycins (ascomycins).","7693638",40]
["13-197 compound","13-197 compound","C584232","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23483555","Pharmacokinetics, protein binding and metabolism of a quinoxaline urea analog as an NF-κB inhibitor in mice and rats by LC-MS/MS.","23483555",40]
["13-aza-13,14-dihydrocopalyl diphosphate","13-aza-13,14-dihydrocopalyl diphosphate","C555700","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21602811","Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase.","21602811",40]
["13-cis-retinal","13-cis-retinal","C031338","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11964248","Light-induced hydrolysis and rebinding of nonisomerizable bacteriorhodopsin pigment.","11964248",40]
["13-cis-retinal","13-cis-retinal","C031338","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21774470","An amino acid residue (S201) in the retinal binding pocket regulates the photoreaction pathway of phoborhodopsin.","21774470",40]
["13-deoxytedanolide","13-deoxytedanolide","C409106","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15598566","13-Deoxytedanolide, a marine sponge-derived antitumor macrolide, binds to the 60S large ribosomal subunit.","15598566",40]
["13-deoxytedanolide","13-deoxytedanolide","C409106","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17321546","The structures of antibiotics bound to the E site region of the 50 S ribosomal subunit of Haloarcula marismortui: 13-deoxytedanolide and girodazole.","17321546",40]
["13-desmethylspirolide C","13-desmethylspirolide C","C517170","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20954707","Human muscarinic acetylcholine receptors are a target of the marine toxin 13-desmethyl C spirolide.","20954707",40]
["13-desmethylspirolide C","13-desmethylspirolide C","C517170","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23343192","Development of a solid-phase receptor-based assay for the detection of cyclic imines using a microsphere-flow cytometry system.","23343192",40]
["13-hydroperoxy-9,11-octadecadienoic acid","13-hydroperoxy-9,11-octadecadienoic acid","C038649","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10509870","The linoleic acid metabolite, 13-HpODE augments the phosphorylation of EGF receptor and SHP-2 leading to their increased association.","10509870",40]
["13-hydroperoxy-9,11-octadecadienoic acid","13-hydroperoxy-9,11-octadecadienoic acid","C038649","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9494102","Mechanism of reaction of myoglobin with the lipid hydroperoxide hydroperoxyoctadecadienoic acid.","9494102",40]
["13-hydroperoxy-9,11-octadecadienoic acid","13-hydroperoxy-9,11-octadecadienoic acid","C038649","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1995,"7774717","Lipid hydroperoxide-induced apoptosis: lack of inhibition by Bcl-2 over-expression.","7774717",40]
["13-hydroxy-6,9,11-octadecatrienoic acid","13-hydroxy-6,9,11-octadecatrienoic acid","C063303","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1990,"2307669","Metabolism of 15-hydroxy-5,8,11,13-eicosatetraenoic acid by MOLT-4 cells and blood T-lymphocytes.","2307669",40]
["13-hydroxy-9,11-octadecadienoic acid","13-hydroxy-9,11-octadecadienoic acid","C024348","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2011,"21068754","Epidermal FABP (FABP5) regulates keratinocyte differentiation by 13(S)-HODE-mediated activation of the NF-κB signaling pathway.","21068754",40]
["13-hydroxy-9,11-octadecadienoic acid","13-hydroxy-9,11-octadecadienoic acid","C024348","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12909723","The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells.","12909723",40]
["13-hydroxy-9,11-octadecadienoic acid","13-hydroxy-9,11-octadecadienoic acid","C024348","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1992,"1330604","13-hydroxyoctadecadienoic acid attenuates oedema formation induced by leukotriene B4 in vivo in rabbit skin.","1330604",40]
["13-hydroxy-9,11-octadecadienoic acid","13-hydroxy-9,11-octadecadienoic acid","C024348","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1990,"2106562","Induction of epidermal hyperproliferation by topical n-3 polyunsaturated fatty acids on guinea pig skin linked to decreased levels of 13-hydroxyoctadecadienoic acid (13-hode).","2106562",40]
["13-O-desmethylascomycin","13-O-desmethylascomycin","C084049","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1993,"7693638","Enzymatic synthesis and immunosuppressive activity of novel desmethylated immunomycins (ascomycins).","7693638",40]
["13-oxo-9,11-octadecadienoic acid","13-oxo-9,11-octadecadienoic acid","C064441","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17604003","13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells.","17604003",40]
["13-valent pneumococcal vaccine","13-valent pneumococcal vaccine","C538862","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2017,"27895132","Protection against Streptococcus pneumoniae Invasive Pathogenesis by a Protein-Based Vaccine Is Achieved by Suppression of Nasopharyngeal Bacterial Density during Influenza A Virus Coinfection.","27895132",40]
["13-valent pneumococcal vaccine","13-valent pneumococcal vaccine","C538862","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2012,"22495545","Pneumococcal conjugate vaccine for adults: a new paradigm.","22495545",40]
["13-valent pneumococcal vaccine","13-valent pneumococcal vaccine","C538862","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"25562448","Lower response to early T-cell-dependent vaccination after neurotrauma or neurosurgery in adults.","25562448",40]
["14-(ethylamino)-8,9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione","14-(ethylamino)-8,9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione","C545120","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2009,"19684251","E6201 [(3S,4R,5Z,8S,9S,11E)-14-(ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-1 and MEK kinase-1: in vitro characterization of its anti-inflammatory and antihyperproliferative activities.","19684251",40]
["14-(ethylamino)-8,9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione","14-(ethylamino)-8,9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione","C545120","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"21698359","Pharmacokinetic characterization of a natural product-inspired novel MEK1 inhibitor E6201 in preclinical species.","21698359",40]
["14-(ethylamino)-8,9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione","14-(ethylamino)-8,9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione","C545120","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2010,"20627998","E6201, a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-1 and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase-1: in vivo effects on cutaneous inflammatory responses by topical administration.","20627998",40]
["14,15-dihydrosiphonodiol","14,15-dihydrosiphonodiol","C548230","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"19802655","Polyacetylene diols with antiproliferative and driving Th1 polarization effects from the marine sponge Callyspongia sp.","19802655",40]
["14,15-dihydrosiphonodiol","14,15-dihydrosiphonodiol","C548230","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"20493278","Polyacetylenediols regulate the function of human monocyte-derived dendritic cells.","20493278",40]
["14,15-dihydrosiphonodiol","14,15-dihydrosiphonodiol","C548230","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2010,"20493278","Polyacetylenediols regulate the function of human monocyte-derived dendritic cells.","20493278",40]
["14,15-epoxy-5,8,11-eicosatrienoic acid","14,15-epoxy-5,8,11-eicosatrienoic acid","C046782","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2003,"12840027","Epoxyeicosatrienoic acids activate transglutaminases in situ and induce cornification of epidermal keratinocytes.","12840027",40]
["14,15-epoxy-5,8,11-eicosatrienoic acid","14,15-epoxy-5,8,11-eicosatrienoic acid","C046782","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16904368","Inhibition of ATP binding to the carboxyl terminus of Kir6.2 by epoxyeicosatrienoic acids.","16904368",40]
["14,15-epoxy-5,8,11-eicosatrienoic acid","14,15-epoxy-5,8,11-eicosatrienoic acid","C046782","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21469660","20-Iodo-14,15-epoxyeicosa-8(Z)-enoyl-3-azidophenylsulfonamide: photoaffinity labeling of a 14,15-epoxyeicosatrienoic acid receptor.","21469660",40]
["14,15-epoxy-5,8,11-eicosatrienoic acid","14,15-epoxy-5,8,11-eicosatrienoic acid","C046782","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9246605","Post-receptor signal transduction and regulation of 14(R),15(S)-epoxyeicosatrienoic acid (14,15-EET) binding in U-937 cells.","9246605",40]
["14,15-secoestra-1,3,5(10)-trien-15-yne-3,17-diol","14,15-secoestra-1,3,5(10)-trien-15-yne-3,17-diol","C050965","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3467792","Mechanism-based inactivation of 17 beta,20 alpha-hydroxysteroid dehydrogenase by an acetylenic secoestradiol.","3467792",40]
["14,21-dihydroxydocosa-4,7,10,12,16,19-hexaenoic acid","14,21-dihydroxydocosa-4,7,10,12,16,19-hexaenoic acid","C569432","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21839062","Autacoid 14S,21R-dihydroxy-docosahexaenoic acid counteracts diabetic impairment of macrophage prohealing functions.","21839062",40]
["14-deoxy-11,12-didehydroandrographolide","14-deoxy-11,12-didehydroandrographolide","C495626","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,1,2009,"19263340","Evaluation of immunomodulatory activity of an extract of andrographolides from Andographis paniculata.","19263340",40]
["14-deoxy-11,12-didehydroandrographolide","14-deoxy-11,12-didehydroandrographolide","C495626","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21219911","Andrographolide and 14-deoxy-11, 12-didehydroandrographolide inhibit cytochrome P450s in HepG2 hepatoma cells.","21219911",40]
["14-deoxyandrographolide","14-deoxyandrographolide","C114791","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,1,2009,"19263340","Evaluation of immunomodulatory activity of an extract of andrographolides from Andographis paniculata.","19263340",40]
["14-deoxyandrographolide","14-deoxyandrographolide","C114791","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20649583","14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway.","20649583",40]
["14-desoxo-3alpha,5alpha,7beta,10,15beta-O-pentaacetyl-14beta-O-butanoyl-10,18-dihydromyrinsol","14-desoxo-3alpha,5alpha,7beta,10,15beta-O-pentaacetyl-14beta-O-butanoyl-10,18-dihydromyrinsol","C554710","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2010,"21128141","New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity.","21128141",40]
["14-desoxo-3beta,5alpha,7beta,10,15beta-O-pentaacetyl-14alpha-O-benzoyl-10,18-dihydromyrinsol","14-desoxo-3beta,5alpha,7beta,10,15beta-O-pentaacetyl-14alpha-O-benzoyl-10,18-dihydromyrinsol","C554709","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2010,"21128141","New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity.","21128141",40]
["14-epi-2alpha-hydroxypropoxy-1alpha,25-dihydroxy-19-nortachysterol","14-epi-2alpha-hydroxypropoxy-1alpha,25-dihydroxy-19-nortachysterol","C583150","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25486940","Synthesis and properties of 14-epi-1α,25-dihydroxy-19-nortachysterol and its 2-substituted derivatives.","25486940",40]
["14-hydroxy-4,14-retro-retinol","14-hydroxy-4,14-retro-retinol","C072014","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1996,"8981025","Metabolism of topical retinaldehyde and retinol by mouse skin in vivo: predominant formation of retinyl esters and identification of 14-hydroxy-4, 14-retro-retinol.","8981025",40]
["14-hydroxy-4,14-retro-retinol","14-hydroxy-4,14-retro-retinol","C072014","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11099483","Retinoids as ligands and coactivators of protein kinase C alpha.","11099483",40]
["14-hydroxy-4,14-retro-retinol","14-hydroxy-4,14-retro-retinol","C072014","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"8292589","Intracellular signaling activity of synthetic (14R)-, (14S)-, and (14RS)-14-hydroxy-4,14-retro-retinol.","8292589",40]
["14-hydroxy-4,14-retro-retinol","14-hydroxy-4,14-retro-retinol","C072014","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1996,"8760808","Retro-retinoids in regulated cell growth and death.","8760808",40]
["14-hydroxyclarithromycin","14-hydroxyclarithromycin","C056228","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1829073","The in-vitro and disc susceptibility testing of clarithromycin and its 14-hydroxy metabolite.","1829073",40]
["14-methoxymetopon","14-methoxymetopon","C081949","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12887410","Binding characteristics of [3H]14-methoxymetopon, a high affinity mu-opioid receptor agonist.","12887410",40]
["14-O-methylmorphine-6-O-sulfate","14-O-methylmorphine-6-O-sulfate","C579042","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22934777","A novel µ-opioid receptor ligand with high in vitro and in vivo agonist efficacy.","22934777",40]
["14-phenylpropoxymetopon","14-phenylpropoxymetopon","C478565","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22677527","Deconstructing 14-phenylpropyloxymetopon: minimal requirements for binding to mu opioid receptors.","22677527",40]
["15(S)-15-methylprostaglandin E1","15(S)-15-methylprostaglandin E1","C025170","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1990,"2339673","Cyclophosphamide and 15(S)-15 methyl PGE1 correct the T/B lymphocyte ratios of NZB/NZW mice.","2339673",40]
["15(S)-15-methylprostaglandin E1","15(S)-15-methylprostaglandin E1","C025170","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1983,"6224618","Preservation of T-lymphocyte activity in autoimmune MRL-lpr mice treated with prostaglandin.","6224618",40]
["15,15'-didehydroastaxanthin","15,15'-didehydroastaxanthin","C052906","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3109483","Resonance Raman study of reconstituted carotenoproteins incorporating astaxanthin and 15,15'-didehydroastaxanthin.","3109483",40]
["15,16-dihydro-11-methylcyclopenta(a)phenanthren-17-one","15,16-dihydro-11-methylcyclopenta(a)phenanthren-17-one","C005765","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1992,"1547520","Tumorigenicity of cyclopenta[a]phenanthrene derivatives and micronucleus induction in mouse skin.","1547520",40]
["15,16-dihydrocyclopenta(a)phenanthren-17-one","15,16-dihydrocyclopenta(a)phenanthren-17-one","C011770","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1992,"1547520","Tumorigenicity of cyclopenta[a]phenanthrene derivatives and micronucleus induction in mouse skin.","1547520",40]
["15,16-dihydrotanshinone I","15,16-dihydrotanshinone I","C401932","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2015,"26553968","Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function.","26553968",40]
["15-acetyldeoxynivalenol","15-acetyldeoxynivalenol","C046760","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,1995,"8560498","Effects of trichothecene structure on cytokine secretion and gene expression in murine CD4+ T-cells.","8560498",40]
["15-demethoxyaclacinomycin T","15-demethoxyaclacinomycin T","C478392","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12878604","Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism.","12878604",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2008,"18463970","15-deoxy-Delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of toll-like receptors 4 and 9 in autoimmune T lymphocyte.","18463970",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2008,"18463970","15-deoxy-Delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of toll-like receptors 4 and 9 in autoimmune T lymphocyte.","18463970",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2002,"12225793","Cyclopentenone prostaglandins induce caspase activation and apoptosis in dendritic cells by a PPAR-gamma-independent mechanism: regulation by inflammatory and T cell-derived stimuli.","12225793",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2003,"12672054","Prostaglandin D2 inhibits the production of interleukin-12 in murine dendritic cells through multiple signaling pathways.","12672054",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2003,"12734337","Prostaglandin D2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells.","12734337",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1603,B1603)","v":"15-deoxy-delta(12,14)-prostaglandin J2"},"15-deoxy-delta(12,14)-prostaglandin J2","C097240","2_KE",826,2,"Keratinocytes","Activation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1603,K1603)","v":"Keratinocytes"},"D015603","Keratinocytes",1,3,2006,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1603,Q1603)","v":"16113051"},"Potentiation of tumor formation by topical administration of 15-deoxy-delta12,14-prostaglandin J2 in a model of skin carcinogenesis.","16113051",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2006,"16572732","Induction of the 72-kilodalton heat shock protein and protection from ultraviolet B-induced cell death in human keratinocytes by repetitive exposure to heat shock or 15-deoxy-delta(12,14)-prostaglandin J2.","16572732",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"20174873","Effects of 15-deoxy-∆¹²,¹⁴-prostaglandin J₂ on the production of IL-8 and the expression of Toll-like receptor 2 in human primary keratinocytes stimulated with lipopolysaccharide.","20174873",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"27185495","15-deoxy prostaglandin J2, the nonenzymatic metabolite of prostaglandin D2, induces apoptosis in keratinocytes of human hair follicles: a possible explanation for prostaglandin D2-mediated inhibition of hair growth.","27185495",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10838168","Peroxisome proliferator-activated receptor gamma1 (PPARgamma1) expresses in rat mesangial cells and PPARgamma agonists modulate its differentiation.","10838168",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2001,"11457450","15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways.","11457450",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11466314","15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit.","11466314",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12684535","The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras.","12684535",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12829715","Peroxisome proliferator-activated receptor gamma and ligands inhibit surfactant protein B gene expression in the lung.","12829715",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14532268","Molecular basis for the direct inhibition of AP-1 DNA binding by 15-deoxy-Delta 12,14-prostaglandin J2.","14532268",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14636064","An endogenous electrophile that modulates the regulatory mechanism of protein turnover: inhibitory effects of 15-deoxy-Delta 12,14-prostaglandin J2 on proteasome.","14636064",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14662774","Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1.","14662774",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15289320","Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism.","15289320",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15531761","Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists.","15531761",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15695504","Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma.","15695504",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16198309","Covalent binding of 15-deoxy-delta12,14-prostaglandin J2 to PPARgamma.","16198309",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17169324","Direct evidence for the covalent modification of glutathione-S-transferase P1-1 by electrophilic prostaglandins: implications for enzyme inactivation and cell survival.","17169324",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17706193","Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis in cancer cells.","17706193",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19360348","Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells.","19360348",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19446632","Methods for imaging and detecting modification of proteins by reactive lipid species.","19446632",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19723057","Effects of 15-deoxy-delta 12, 14-prostaglandin J2 on the expression of p53 in MCF-7 cells.","19723057",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19723058","15-Deoxy-delta 12, 14-prostaglandin J2 induces upregulation of multidrug resistance-associated protein 1 via Nrf2 activation in human breast cancer cells.","19723058",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"20019843","Albumin-binding and tumor vasculature determine the antitumor effect of 15-deoxy-Delta-(12,14)-prostaglandin-J(2) in vivo.","20019843",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21374648","High-performance affinity purification for identification of 15-deoxy-Δ 12,14 -PGJ₂ interacting factors using magnetic nanobeads.","21374648",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"16337105","Inhibition of skin sclerosis by 15deoxy delta12,14-prostaglandin J2 and retrovirally transfected prostaglandin D synthase in a mouse model of bleomycin-induced scleroderma.","16337105",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"11801678","15-deoxy-Delta 12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway.","11801678",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2002,"11849312","Prostaglandin D(2), its metabolite 15-d-PGJ(2), and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells.","11849312",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"11859145","Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis.","11859145",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2002,"12225793","Cyclopentenone prostaglandins induce caspase activation and apoptosis in dendritic cells by a PPAR-gamma-independent mechanism: regulation by inflammatory and T cell-derived stimuli.","12225793",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2003,"12707336","The cyclopentenone-type prostaglandin 15-deoxy-delta 12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms.","12707336",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2003,"14522590","Peroxisome proliferator-activated receptor gamma ligands attenuate immunological symptoms of experimental allergic asthma.","14522590",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2006,"16939878","15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism.","16939878",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17371958","15-deoxy-Delta12,14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors.","17371958",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17673570","Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in T lymphocytes.","17673570",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22700433","15-Deoxy-Δ¹²,¹⁴-prostaglandin J₂-glycerol, a putative metabolite of 2-arachidonyl glycerol and a peroxisome proliferator-activated receptor γ ligand, modulates nuclear factor of activated T cells.","22700433",40]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23333326","15-Deoxy-Δ(12,14)-prostaglandin J2 inhibits IL-13 production in T cells via an NF-κB-dependent mechanism.","23333326",40]
["15-deoxymethylspergualin","15-deoxymethylspergualin","C059810","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1989,"2524464","In vitro immunosuppressive properties of spergualins to murine T cell response.","2524464",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2003,"14573767","Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor.","14573767",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2014,"25171226","Immunopathogenesis of HIV infection in cocaine users: role of arachidonic acid.","25171226",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2012,"22440736","Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia.","22440736",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2017,"28292936","Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ12,14-Prostamide J2, as a Selective Antitumor Therapeutic.","28292936",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15745794","Design, synthesis, and biological activity of novel PPARgamma ligands based on rosiglitazone and 15d-PGJ2.","15745794",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16006125","Molecular recognition of 15-deoxy-delta(12,14)-prostaglandin J2 by nuclear factor-kappa B and other cellular proteins.","16006125",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16236024","Spectroscopic analyses of the binding kinetics of 15d-PGJ2 to the PPARgamma ligand-binding domain by multi-wavelength global fitting.","16236024",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16291835","Identification of novel protein targets for modification by 15-deoxy-Delta12,14-prostaglandin J2 in mesangial cells reveals multiple interactions with the cytoskeleton.","16291835",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16979589","Addition of electrophilic lipids to actin alters filament structure.","16979589",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"19912441","PPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells.","19912441",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23192983","Prostaglandin 15d-PGJ(2) inhibits androgen receptor signaling in prostate cancer cells.","23192983",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23707573","Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: molecular modeling with biological evaluation.","23707573",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28716729","Study of new interactions of glitazone's stereoisomers and the endogenous ligand 15d-PGJ2 on six different PPAR gamma proteins.","28716729",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2003,"14703419","[Peroxisome proliferation-activated receptor-gamma ligands ameliorate autoimmune myocarditis associated with inhibition of T cell immunity].","14703419",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2009,"19888466","Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells.","19888466",40]
["15-deoxyprostaglandin J2","15-deoxyprostaglandin J2","C477819","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21690493","Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells.","21690493",40]
["15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","C025086","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2500117","Specific high affinity binding of lipoxygenase metabolites of arachidonic acid by liver fatty acid binding protein.","2500117",40]
["15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","C025086","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3086322","Purification of arachidonate 5-lipoxygenase from porcine leukocytes and its reactivity with hydroperoxyeicosatetraenoic acids.","3086322",40]
["15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","C025086","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1981,"6274465","The inflammatory effects of hydroperoxy and hydroxy acid products of arachidonate lipoxygenase in rabbit skin.","6274465",40]
["15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","C025086","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1988,"2837956","Role of lipoxygenase metabolites of arachidonic acid in T cell activation.","2837956",40]
["15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","C025086","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1985,"2981258","Effect of lipoxygenase metabolites of arachidonic acid on proliferation of human T cells and T cell subsets.","2981258",40]
["15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","C025086","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"2996948","Lipoxygenase pathways of macrophages.","2996948",40]
["15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","C025086","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1984,"6231646","Modulation of Fc gamma receptors on I cells and monocytes by 15 hydroperoxyeicosatetranoic acid.","6231646",40]
["15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","C025086","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1995,"7774717","Lipid hydroperoxide-induced apoptosis: lack of inhibition by Bcl-2 over-expression.","7774717",40]
["15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","15-hydroperoxy-5,8,11,13-eicosatetraenoic acid","C025086","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1994,"8288627","Lipid hydroperoxides induce apoptosis in T cells displaying a HIV-associated glutathione peroxidase deficiency.","8288627",40]
["15-hydroperoxyabietic acid","15-hydroperoxyabietic acid","C055834","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1992,"1288422","Rosin allergy: identification of a dehydroabietic acid peroxide with allergenic properties.","1288422",40]
["15-hydroperoxyabietic acid","15-hydroperoxyabietic acid","C055834","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1994,"9868506","Allergenic components in modified and unmodified rosin. Chemical characterization and studies of allergenic activity.","9868506",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1667,B1667)","v":"15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid"},"15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid","D019796","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1667,K1667)","v":"Protein Binding"},"D011485","Protein Binding",1,1,1991,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1667,Q1667)","v":"1830308"},"Differential effect of pH on thromboxane A2/prostaglandin H2 receptor agonist and antagonist binding in human platelets.","1830308",40]
["15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid","15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid","D019796","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2521385","Regulation of thromboxane receptor activation in human platelets.","2521385",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1984,"6199312","Effect of 15-hydroxyeicosatetraenoic acid (15-HETE) on anti-immunoglobulin E- and calcium ionophore-induced histamine release from human leukocytes. Comparison with the effects of eicosatetraynoic acid and nordihydroguaiaretic acid.","6199312",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10224163","Albumin modifies the metabolism of hydroxyeicosatetraenoic acids via 12-lipoxygenase in human platelets.","10224163",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19838939","Gamma tocopherol upregulates the expression of 15-S-HETE and induces growth arrest through a PPAR gamma-dependent mechanism in PC-3 human prostate cancer cells.","19838939",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2500117","Specific high affinity binding of lipoxygenase metabolites of arachidonic acid by liver fatty acid binding protein.","2500117",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"10940814","Assessment of toxic potential of industrial chemicals using a cultured human bioartificial skin model: production of interleukin 1alpha and hydroxyeicosatetraenoic acids.","10940814",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2556975","15-hydroxyeicosatetraenoic acid (15-HETE) specifically inhibits the LTB4-induced skin response.","2556975",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1992,"1727629","Beta-oxidation of 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid by MOLT-4 lymphocytes.","1727629",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1990,"2124949","Lipoxygenase inhibitors suppress intracellular calcium rise induced by ionomycin in rat thymocytes.","2124949",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1990,"2307669","Metabolism of 15-hydroxy-5,8,11,13-eicosatetraenoic acid by MOLT-4 cells and blood T-lymphocytes.","2307669",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1988,"2837958","Effect of arachidonic acid metabolites on thymocyte tolerance.","2837958",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"2996948","Lipoxygenase pathways of macrophages.","2996948",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6804096","Regulation of T-lymphocyte mitogenesis by the leukocyte product 15-hydroxy-eicosatetraenoic acid (15-HETE).","6804096",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1997,"9191291","Regulation of human T-lymphocyte proliferative responses by the lipoxygenase product 15-HETE.","9191291",40]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1997,"9388724","Activation of mitogen-induced T-lymphocyte proliferation by leukotriene C-4.","9388724",40]
["15-hydroxyeicosatrienoic acid","15-hydroxyeicosatrienoic acid","C095123","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1995,"7640878","Incorporation of 15-hydroxyeicosatrienoic acid in specific phospholipids of cultured human keratinocytes and psoriatic plaques.","7640878",40]
["15-hydroxyeicosatrienoic acid","15-hydroxyeicosatrienoic acid","C095123","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"10994774","15-hydroxyeicosatrienoic acid (15-HETrE) suppresses epidermal hyperproliferation via the modulation of nuclear transcription factor (AP-1) and apoptosis.","10994774",40]
["15-keto-13,14-dihydroprostaglandin E2","15-keto-13,14-dihydroprostaglandin E2","C025087","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1997,"9115911","In vivo formation of prostaglandin E1 and prostaglandin E2 in atopic dermatitis.","9115911",40]
["15-keto-13,14-dihydroprostaglandin E2","15-keto-13,14-dihydroprostaglandin E2","C025087","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1985,"3859200","Actions of prostaglandin E2 metabolites on skin microcirculation.","3859200",40]
["15-ketoprostaglandin E","15-ketoprostaglandin E","C011008","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6698991","Albumin-eicosanoid interactions. A model system to determine their attributes and inhibition.","6698991",40]
["15-ketoprostaglandin E2","15-ketoprostaglandin E2","C026346","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"19000823","Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2.","19000823",40]
["15-ketoprostaglandin E2","15-ketoprostaglandin E2","C026346","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1985,"3859200","Actions of prostaglandin E2 metabolites on skin microcirculation.","3859200",40]
["15-methoxylabda-8(17),13-dien-16,15-olide","15-methoxylabda-8(17),13-dien-16,15-olide","C570586","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"22071304","Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells.","22071304",40]
["15-O-desmethylascomycin","15-O-desmethylascomycin","C084048","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1993,"7693638","Enzymatic synthesis and immunosuppressive activity of novel desmethylated immunomycins (ascomycins).","7693638",40]
["15-oxospiramilactone","15-oxospiramilactone","C560615","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21321609","A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/β-catenin signaling and colon cancer cell tumorigenesis.","21321609",40]
["16 alpha,17-epoxy-3 beta-hydroxy-5 alpha-pregnan-20-one","16 alpha,17-epoxy-3 beta-hydroxy-5 alpha-pregnan-20-one","C028109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21155814","Preclinical pharmacokinetics, dose proportionality, gender difference and protein binding study of 16-dehydropregnenolone, an antihyperlipidemic agent, in rats.","21155814",40]
["16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione","16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione","C020175","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2919163","Binding of hormone accelerates the kinetics of glucocorticoid and progesterone receptor binding to DNA.","2919163",40]
["16-(2'-O-glucopyranosylglucopyranosyloxy)hexadecanoic acid 1',4''-lactone 6',6''-diacetate","16-(2'-O-glucopyranosylglucopyranosyloxy)hexadecanoic acid 1',4''-lactone 6',6''-diacetate","C067958","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2009,"19844071","Natural synergism of acid and lactone type mixed sophorolipids in interfacial activities and cytotoxicities.","19844071",40]
["16-(4-fluorophenoxy)-3-oxa-5,6,15-trihydroxy-7,9,11,13-hexadecatetraenoic acid","16-(4-fluorophenoxy)-3-oxa-5,6,15-trihydroxy-7,9,11,13-hexadecatetraenoic acid","C485114","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,1,2004,"15056011","Novel 3-oxa lipoxin A4 analogues with enhanced chemical and metabolic stability have anti-inflammatory activity in vivo.","15056011",40]
["16-(4-fluorophenoxy)-3-oxa-5,6,15-trihydroxy-7,9,13-hexadecatrien-11-ynoic acid","16-(4-fluorophenoxy)-3-oxa-5,6,15-trihydroxy-7,9,13-hexadecatrien-11-ynoic acid","C485115","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,1,2004,"15056011","Novel 3-oxa lipoxin A4 analogues with enhanced chemical and metabolic stability have anti-inflammatory activity in vivo.","15056011",40]
["16,16-Dimethylprostaglandin E2","16,16-Dimethylprostaglandin E2","D015064","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,2,1992,"1373359","Protective effect of 16,16-dimethyl prostaglandin E2 on isolated rat hepatocytes against complement-mediated immune attack.","1373359",40]
["16,16-Dimethylprostaglandin E2","16,16-Dimethylprostaglandin E2","D015064","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1991,"1825425","Effect of di-M-PGE2 on T cell differentiation. Flow cytometry study at thymus level.","1825425",40]
["16,16-Dimethylprostaglandin E2","16,16-Dimethylprostaglandin E2","D015064","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2528784","Effect of prostaglandin E in multiple experimental models. VI. Effect on T-cell subsets.","2528784",40]
["16,16-Dimethylprostaglandin E2","16,16-Dimethylprostaglandin E2","D015064","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1985,"3871180","Alterations in serum antibody and peripheral T-lymphocyte subsets resulting from treatment of murine immune complex glomerulonephritis with PGE2.","3871180",40]
["16,16-Dimethylprostaglandin E2","16,16-Dimethylprostaglandin E2","D015064","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1981,"6975108","[Restoration of the humoral immune response in mice immunosuppressed by treatment with di-M-PGE2].","6975108",40]
["16,16-Dimethylprostaglandin E2","16,16-Dimethylprostaglandin E2","D015064","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6983392","Induction of serum thymic-like activity in adult thymectomized mice by a synthetic analog of PGE2.","6983392",40]
["16,16-Dimethylprostaglandin E2","16,16-Dimethylprostaglandin E2","D015064","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6983915","The differential effects of PGE on the immune response in normal and immunosuppressed mice.","6983915",40]
["16,16-Dimethylprostaglandin E2","16,16-Dimethylprostaglandin E2","D015064","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1998,"9481403","Pretreatment of donor stimulator cells by 16,16 dimethyl prostaglandin E2 influences the recipient immune response.","9481403",40]
["16,22-diketocholesterol","16,22-diketocholesterol","C586241","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23756172","Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.","23756172",40]
["16a,17-dihydroxykauran-19-oic acid","16a,17-dihydroxykauran-19-oic acid","C095248","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21992237","Epidermal regeneration by ent-16α, 17-dihydroxy-kauran-19-oic acid isolated from Siegesbeckia pubescens.","21992237",40]
["16-acetylgitoxin","16-acetylgitoxin","C025972","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7251233","On the plasma protein binding of 16-acetyl-gitoxin.","7251233",40]
["16-fluoro-5-androsten-17-one","16-fluoro-5-androsten-17-one","C066783","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1992,"1381206","Dehydroepiandrosterone (DHEA) and synthetic DHEA analogs are modest inhibitors of HIV-1 IIIB replication.","1381206",40]
["16-mercaptohexadecanoic acid","16-mercaptohexadecanoic acid","C450319","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11834780","Protein nanoarrays generated by dip-pen nanolithography.","11834780",40]
["16-mercaptohexadecanoic acid","16-mercaptohexadecanoic acid","C450319","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21755270","Surface characterization and efficiency of a matrix-free and flat carboxylated gold sensor chip for surface plasmon resonance (SPR).","21755270",40]
["16-mercaptohexadecanoic acid","16-mercaptohexadecanoic acid","C450319","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26934871","Regeneration of a thiolated and antibody functionalized GaAs (001) surface using wet chemical processes.","26934871",40]
["16-O-beta-D-glucopyranosyl-19-deoxycinncassiol G","16-O-beta-D-glucopyranosyl-19-deoxycinncassiol G","C000602062","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2014,"25089845","Diterpenoids with Immunosuppressive Activities from Cinnamomum cassia.","25089845",40]
["16-phyllocladanol","16-phyllocladanol","C528687","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2008,"18334227","Diterpene, 16-phyllocladanol enhances Th1 polarization induced by LPS-primed DC, but not TNF-alpha-primed DC.","18334227",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2009,"19690146","Heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin enhances EphA2+ tumor cell recognition by specific CD8+ T cells.","19690146",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2012,"22552283","Combination therapy with HSP90 inhibitor 17-DMAG reconditions the tumor microenvironment to improve recruitment of therapeutic T cells.","22552283",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2008,"17579866","Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.","17579866",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2014,"24796797","Hsp90 blockade modulates bullous pemphigoid IgG-induced IL-8 production by keratinocytes.","24796797",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11855755","Pharmacokinetics, tissue distribution, and metabolism of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (NSC 707545) in CD2F1 mice and Fischer 344 rats.","11855755",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17662999","Mechanistic studies on Hsp90 inhibition by ansamycin derivatives.","17662999",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24849514","Targeting oncoprotein stability overcomes drug resistance caused by FLT3 kinase domain mutations.","24849514",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26662567","17-DMAG induces heat shock protein 90 functional impairment in human bladder cancer cells: knocking down the hallmark traits of malignancy.","26662567",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21490339","Heat-shock protein 90 inhibition in autoimmunity to type VII collagen: evidence that nonmalignant plasma cells are not therapeutic targets.","21490339",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2009,"19657113","Selective depletion of alloreactive T cells by targeted therapy of heat shock protein 90: a novel strategy for control of graft-versus-host disease.","19657113",40]
["17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","17-(dimethylaminoethylamino)-17-demethoxygeldanamycin","C448659","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2009,"19708781","Geldanamycin analog 17-DMAG inhibits iNOS and caspases in gamma-irradiated human T cells.","19708781",40]
["17,18,19,20-tetranor-16-(3-biphenyl)-2,3,13,14-tetradehydroprostaglandin E1","17,18,19,20-tetranor-16-(3-biphenyl)-2,3,13,14-tetradehydroprostaglandin E1","C561620","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21383594","The anti-inflammatory mechanism of prostaglandin e2 receptor 4 activation in rat experimental autoimmune myocarditis.","21383594",40]
["17,20-dihydroxyvitamin D2","17,20-dihydroxyvitamin D2","C512457","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2006,"16817851","An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2.","16817851",40]
["17-acetoxyjolkinolide B","17-acetoxyjolkinolide B","C530787","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2008,"18566223","17-Acetoxyjolkinolide B irreversibly inhibits IkappaB kinase and induces apoptosis of tumor cells.","18566223",40]
["17-amino-17-demethoxygeldanamycin -C2-galactose","17-amino-17-demethoxygeldanamycin -C2-galactose","C515135","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"17034135","Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugates.","17034135",40]
["17-aminogeldanamycin","17-aminogeldanamycin","C515136","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"17034135","Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugates.","17034135",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1731,B1731)","v":"17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-((3'-isoquinolyl)acetamido)morphinan"},"17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-((3'-isoquinolyl)acetamido)morphinan","C550365","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1731,K1731)","v":"Protein Binding"},"D011485","Protein Binding",1,2,2011,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1731,Q1731)","v":"21685245"},"Preclinical disposition (in vitro) of novel μ-opioid receptor selective antagonists.","21685245",40]
["17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-((4'-pyridyl)acetamido)morphinan","17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-((4'-pyridyl)acetamido)morphinan","C550364","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21685245","Preclinical disposition (in vitro) of novel μ-opioid receptor selective antagonists.","21685245",40]
["17-cyclopropylmethyl-6,7-didehydro-4,5-epoxy-5'-guanidinyl-3,14-dihydroxyindolo(2',3'-6,7)morphinan","17-cyclopropylmethyl-6,7-didehydro-4,5-epoxy-5'-guanidinyl-3,14-dihydroxyindolo(2',3'-6,7)morphinan","C411465","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23976952","Selective κ opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters.","23976952",40]
["17-cyclopropylmethyl-6,7-didehydro-quinolino(2',3'-6,7)morphinan-4-ol","17-cyclopropylmethyl-6,7-didehydro-quinolino(2',3'-6,7)morphinan-4-ol","C572008","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"22197670","Synthesis of quinolinomorphinan-4-ol derivatives as δ opioid receptor agonists.","22197670",40]
["17-hydroxy-4,6,8(14)-androstatriene-3-one","17-hydroxy-4,6,8(14)-androstatriene-3-one","C051278","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3801517","The binding of fluorescent 4,6,8(14)-triene-3-one steroids to cyclodextrins as a model for steroid-protein interactions.","3801517",40]
["17-hydroxy-4,6,8(14)-pregnatriene-3,20-dione","17-hydroxy-4,6,8(14)-pregnatriene-3,20-dione","C051279","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3801517","The binding of fluorescent 4,6,8(14)-triene-3-one steroids to cyclodextrins as a model for steroid-protein interactions.","3801517",40]
["17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid","17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid","C062894","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17182589","Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness.","17182589",40]
["17-O-((2-(3-(4-azido-3-iodophenyl)propionamido)ethyl)carbamyl)estradiol-3-N-bis(chloroethyl)carbamate","17-O-((2-(3-(4-azido-3-iodophenyl)propionamido)ethyl)carbamyl)estradiol-3-N-bis(chloroethyl)carbamate","C090647","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7969073","Interaction of an estramustine photoaffinity analogue with cytoskeletal proteins in prostate carcinoma cells.","7969073",40]
["17-phenyltrinorprostaglandin E2","17-phenyltrinorprostaglandin E2","C092396","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2004,"15140225","Proteinase-activated receptor-2 stimulates prostaglandin production in keratinocytes: analysis of prostaglandin receptors on human melanocytes and effects of PGE2 and PGF2alpha on melanocyte dendricity.","15140225",40]
["18,19-dihydroetorphine","18,19-dihydroetorphine","C034765","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11160640","Pharmacokinetic and pharmacodynamic evaluations of a potent analgesic, dihydroetorphine, in hairless rat.","11160640",40]
["18,19-dihydroetorphine","18,19-dihydroetorphine","C034765","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"9863246","[Studies on transdermal delivery system of dihydroetorphine hydrochloride].","9863246",40]
["1843U89","1843U89","C079601","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8805515","The complex of the anti-cancer therapeutic, BW1843U89, with thymidylate synthase at 2.0 A resolution: implications for a new mode of inhibition.","8805515",40]
["18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate","18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate","C521270","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2016,"26869766","Amelioration of concanavalin A-induced autoimmune hepatitis by magnesium isoglycyrrhizinate through inhibition of CD4(+)CD25(-)CD69(+) subset proliferation.","26869766",40]
["18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate","18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate","C521270","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,-1,2010,"20707204","[Effect of magnesium isoglycyrrhizinate on allergy contact dermatitis (ACD) in mice].","20707204",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2010,"19897483","18Beta-glycyrrhetinic acid ameliorates acute Propionibacterium acnes-induced liver injury through inhibition of macrophage inflammatory protein-1alpha.","19897483",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2010,"19897483","18Beta-glycyrrhetinic acid ameliorates acute Propionibacterium acnes-induced liver injury through inhibition of macrophage inflammatory protein-1alpha.","19897483",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2013,"23438306","18β-Glycyrrhetinic acid from licorice root impairs dendritic cells maturation and Th1 immune responses.","23438306",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2016,"27018762","Decline in Immunological Responses Mediated by Dendritic Cells in Mice Treated with 18α-Glycyrrhetinic Acid.","27018762",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,-1,2012,"22832704","A novel transdermal fomulation of 18β-glycyrrhetic acid with lysine for improving bioavailability and efficacy.","22832704",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,-1,2012,"22077323","Enhanced transdermal delivery of 18β-glycyrrhetic acid via elastic vesicles: in vitro and in vivo evaluation.","22077323",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,2013,"23746951","18β-glycyrrhetinic acid induces immunological adjuvant activity of Th1 against Candida albicans surface mannan extract.","23746951",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21737643","18beta-glycyrrhetinic acid and glabridin prevent oxidative DNA fragmentation in UVB-irradiated human keratinocyte cultures.","21737643",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2017,"28813533","18ß-glycyrrhetinic acid derivative promotes proliferation, migration and aquaporin-3 expression in human dermal fibroblasts.","28813533",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11756680","Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture.","11756680",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"27403722","Novel Chemical Ligands to Ebola Virus and Marburg Virus Nucleoproteins Identified by Combining Affinity Mass Spectrometry and Metabolomics Approaches.","27403722",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23114775","18β-Glycyrrhetinic acid inhibits methicillin-resistant Staphylococcus aureus survival and attenuates virulence gene expression.","23114775",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"28736984","Randomized, double-blinded, placebo-controlled pilot study on the effects of topical blackcurrant emulsion enriched in essential fatty acids, ceramides and 18-beta glycyrrhetinic acid on clinical signs and skin barrier function in dogs with atopic dermatitis.","28736984",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2010,"20682015","18β-glycyrrhetinic acid inhibits periodontitis via glucocorticoid-independent nuclear factor-κB inactivation in interleukin-10-deficient mice.","20682015",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2013,"22991231","18β-glycyrrhetinic acid inhibits hepatocellular carcinoma development by reversing hepatic stellate cell-mediated immunosuppression in mice.","22991231",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"23152913","18β-glycyrrhetinic acid delivered orally induces isolated lymphoid follicle maturation at the intestinal mucosa and attenuates rotavirus shedding.","23152913",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23707333","18β-Glycyrrhetinic acid potently inhibits Kv1.3 potassium channels and T cell activation in human Jurkat T cells.","23707333",40]
["18alpha-glycyrrhetinic acid","18alpha-glycyrrhetinic acid","C119129","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"26329786","18β-glycyrrhetinic acid suppresses experimental autoimmune encephalomyelitis through inhibition of microglia activation and promotion of remyelination.","26329786",40]
["18-crown-6","18-crown-6","C015762","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16766206","Using ESI-MS to probe protein structure by site-specific noncovalent attachment of 18-crown-6.","16766206",40]
["18-crown-6","18-crown-6","C015762","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22134366","Synthesis of N-(2-chloro purin-6-yl) aza-18-crown-6 and its interaction with human serum albumin.","22134366",40]
["18-crown-6","18-crown-6","C015762","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22926972","Structural and energetic effects in the molecular recognition of acetylated amino acids by 18-crown-6.","22926972",40]
["18F-ST889","18F-ST889","C574177","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22483590","Radiofluorinated histamine H₃ receptor antagonist as a potential probe for in vivo PET imaging: radiosynthesis and pharmacological evaluation.","22483590",40]
["18-hydroxyperseanol","18-hydroxyperseanol","C000602063","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2014,"25089845","Diterpenoids with Immunosuppressive Activities from Cinnamomum cassia.","25089845",40]
["18-methoxycoronaridine","18-methoxycoronaridine","C103345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20303928","Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states.","20303928",40]
["19K antigen, Mycobacterium tuberculosis","19K antigen, Mycobacterium tuberculosis","C510665","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2005,"16249121","Strain-specific mycobacterial lipids and the stimulation of protective immunity to tuberculosis.","16249121",40]
["19-nor-1,24,25,26-tetrahydroxyvitamin D2","19-nor-1,24,25,26-tetrahydroxyvitamin D2","C426835","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2001,"11370854","In vitro metabolism of 19-nor-1alpha, 25-(OH)2D2 in cultured cell lines: inducible synthesis of lipid- and water-soluble metabolites.","11370854",40]
["19-nor-1,24,25,28-tetrahydroxyvitamin D2","19-nor-1,24,25,28-tetrahydroxyvitamin D2","C426834","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2001,"11370854","In vitro metabolism of 19-nor-1alpha, 25-(OH)2D2 in cultured cell lines: inducible synthesis of lipid- and water-soluble metabolites.","11370854",40]
["19-nor-1,24,25-trihydroxyvitamin D2","19-nor-1,24,25-trihydroxyvitamin D2","C426833","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2001,"11370854","In vitro metabolism of 19-nor-1alpha, 25-(OH)2D2 in cultured cell lines: inducible synthesis of lipid- and water-soluble metabolites.","11370854",40]
["19-nor-1,25-dihydroxyvitamin D3","19-nor-1,25-dihydroxyvitamin D3","C555222","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23788554","Recent developments of 19-nor-1,25-dihydroxyvitamin D3 analogues.","23788554",40]
["19-norprogesterone","19-norprogesterone","C030703","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14667982","Nestorone: clinical applications for contraception and HRT.","14667982",40]
["1a alloantigen, human","1a alloantigen, human","C039231","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,2002,"11861302","HPA-1a phenotype-genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet beta 3 integrin that disrupts the HPA-1a epitope.","11861302",40]
["1a alloantigen, human","1a alloantigen, human","C039231","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,2008,"18045240","Immunologic and structural analysis of eight novel domain-deletion beta3 integrin peptides designed for detection of HPA-1 antibodies.","18045240",40]
["1a alloantigen, human","1a alloantigen, human","C039231","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,2,1991,"1926322","Captopril-enhanced binding of PlA1 (HPA-1a) antibodies in posttransfusion purpura.","1926322",40]
["1a alloantigen, human","1a alloantigen, human","C039231","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1985,"3162148","[Alloimmune thrombocytopenia in newborn infants caused by specific anti-platelet antibodies].","3162148",40]
["1a alloantigen, human","1a alloantigen, human","C039231","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1988,"3280252","Neonatal alloimmune thrombocytopenia: a clinical perspective.","3280252",40]
["1a alloantigen, human","1a alloantigen, human","C039231","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1988,"3349816","In utero fetal sampling in neonatal alloimmune thrombocytopenia: justification and usefulness.","3349816",40]
["1a alloantigen, human","1a alloantigen, human","C039231","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1988,"3349817","Screening for neonatal alloimmune thrombocytopenia: an economic perspective.","3349817",40]
["1a alloantigen, human","1a alloantigen, human","C039231","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1988,"3355887","GPIIIa-related PLA1 antigens with different molecular weights: studies in platelets, endothelial cells, and megakaryocytes.","3355887",40]
["1a alloantigen, human","1a alloantigen, human","C039231","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1994,"7986721","Analysis of immunoglobulin class, IgG subclass and titre of HPA-1a antibodies in alloimmunized mothers giving birth to babies with or without neonatal alloimmune thrombocytopenia.","7986721",40]
["1a alloantigen, human","1a alloantigen, human","C039231","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2009,"19494351","Naturally processed peptides spanning the HPA-1a polymorphism are efficiently generated and displayed from platelet glycoprotein by HLA-DRB3*0101-positive antigen-presenting cells.","19494351",40]
["1a alloantigen, human","1a alloantigen, human","C039231","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12406067","Human platelet alloantigen polymorphism in Glanzmann's thrombasthenia and its impact on the severity of the disease.","12406067",40]
["1a alloantigen, human","1a alloantigen, human","C039231","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18045240","Immunologic and structural analysis of eight novel domain-deletion beta3 integrin peptides designed for detection of HPA-1 antibodies.","18045240",40]
["1a alloantigen, human","1a alloantigen, human","C039231","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18654666","Developing recombinant HPA-1a-specific antibodies with abrogated Fcgamma receptor binding for the treatment of fetomaternal alloimmune thrombocytopenia.","18654666",40]
["1a alloantigen, human","1a alloantigen, human","C039231","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18710823","What's happening--probing of HPA-1a antigen-antibody interaction by surface plasmon resonance technology.","18710823",40]
["1a alloantigen, human","1a alloantigen, human","C039231","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19000229","Blockade of maternal anti-HPA-1a-mediated platelet clearance by an HPA-1a epitope-specific F(ab') in an in vivo mouse model of alloimmune thrombocytopenia.","19000229",40]
["1a alloantigen, human","1a alloantigen, human","C039231","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22036924","Human platelet antigen 1a epitopes are dependent on the cation-regulated conformation of integrin α(IIb)β(3) (GPIIb/IIIa).","22036924",40]
["1a alloantigen, human","1a alloantigen, human","C039231","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23645838","Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia.","23645838",40]
["1a alloantigen, human","1a alloantigen, human","C039231","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25972474","Characterization of a human platelet antigen-1a-specific monoclonal antibody derived from a B cell from a woman alloimmunized in pregnancy.","25972474",40]
["1a alloantigen, human","1a alloantigen, human","C039231","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28427432","Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: a laboratory study using an in vitro model.","28427432",40]
["1a alloantigen, human","1a alloantigen, human","C039231","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"7505078","Lack of binding of peptides carrying the human platelet antigen 1 (HPA-1) dimorphism to purified HLA-DRw52a molecules.","7505078",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1795,B1795)","v":"1a alloantigen, human"},"1a alloantigen, human","C039231","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1795,K1795)","v":"T-Lymphocytes"},"D013601","T-Lymphocytes",1,1,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1795,Q1795)","v":"16178861"},"Reactivity of T cells from women with antibodies to the human platelet antigen (HPA)-1a to peptides encompassing the HPA-1 polymorphism.","16178861",40]
["1a alloantigen, human","1a alloantigen, human","C039231","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1993,"7505078","Lack of binding of peptides carrying the human platelet antigen 1 (HPA-1) dimorphism to purified HLA-DRw52a molecules.","7505078",40]
["1a alloantigen, human","1a alloantigen, human","C039231","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1996,"8878431","Molecular identification of T cells that respond in a primary bulk culture to a peptide derived from a platelet glycoprotein implicated in neonatal alloimmune thrombocytopenia.","8878431",40]
["1-acetamido-2-(3-carboxy-2-hydroxyphenyl)ethylboronic acid","1-acetamido-2-(3-carboxy-2-hydroxyphenyl)ethylboronic acid","C410123","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10820001","Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 beta-Lactamase(,).","10820001",40]
["1'-acetoxychavicol acetate","1'-acetoxychavicol acetate","C047948","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2015,"25661358","Anti-inflammatory effect of water-soluble complex of 1'-acetoxychavicol acetate with highly branched β-1,3-glucan on contact dermatitis.","25661358",40]
["1'-acetoxychavicol acetate","1'-acetoxychavicol acetate","C047948","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8784473","1'-Acetoxychavicol acetate, a superoxide anion generation inhibitor, potently inhibits tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in ICR mouse skin.","8784473",40]
["1'-acetoxychavicol acetate","1'-acetoxychavicol acetate","C047948","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9809987","Suppression of tumor promoter-induced oxidative stress and inflammatory responses in mouse skin by a superoxide generation inhibitor 1'-acetoxychavicol acetate.","9809987",40]
["1-acetylhydrazinylthiophene formamidine","1-acetylhydrazinylthiophene formamidine","C030806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"7252575","Trial of a new compound as a chemical radioprotector and its effect on melatonin.","7252575",40]
["1-acetyl-N-(4-((aminoiminomethyl)amino)-1-(2-benzothiazolylcarbonyl)butyl)-4-hydroxy-2-pyrrolidinecarboxamide","1-acetyl-N-(4-((aminoiminomethyl)amino)-1-(2-benzothiazolylcarbonyl)butyl)-4-hydroxy-2-pyrrolidinecarboxamide","C477196","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12930148","Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone.","12930148",40]
["1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine","1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine","C078632","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15049708","Generation of singlet oxygen induces phospholipid scrambling in human erythrocytes.","15049708",40]
["1-acyl-2-acetyl-sn-glycero-3-phosphocholine","1-acyl-2-acetyl-sn-glycero-3-phosphocholine","C069030","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1997,"9246603","Identification of sn-2 acetyl glycerophosphocholines in human keratinocytes.","9246603",40]
["1-allyl-2-methyl-3-hydroxypyrid-4-one","1-allyl-2-methyl-3-hydroxypyrid-4-one","C507647","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16798643","Iron mobilization from transferrin and non-transferrin-bound-iron by deferiprone. Implications in the treatment of thalassemia, anemia of chronic disease, cancer and other conditions.","16798643",40]
["1-allyl-3-methylimidazolium","1-allyl-3-methylimidazolium","C544334","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23295204","Effect of two imidazolium derivatives of ionic liquids on the structure and activity of adenosine deaminase.","23295204",40]
["1alpha,20-dihydroxyvitamin D3","1alpha,20-dihydroxyvitamin D3","C539020","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2008,"19000766","Metabolism of 1alpha-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1alpha,20-dihydroxyvitamin D3.","19000766",40]
["1alpha-hydroxymethyl-16-ene-24,24-difluoro-25-hydroxy-26,27-bis-homovitamin D3","1alpha-hydroxymethyl-16-ene-24,24-difluoro-25-hydroxy-26,27-bis-homovitamin D3","C580739","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2012,"22907250","Differential photoprotective effects of 1,25-dihydroxyvitamin D3 and a low calcaemic deltanoid.","22907250",40]
["1alpha-hydroxymethyl-16-ene-24,24-difluoro-25-hydroxy-26,27-bis-homovitamin D3","1alpha-hydroxymethyl-16-ene-24,24-difluoro-25-hydroxy-26,27-bis-homovitamin D3","C580739","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22907250","Differential photoprotective effects of 1,25-dihydroxyvitamin D3 and a low calcaemic deltanoid.","22907250",40]
["1-amino-2-methylanthraquinone","1-amino-2-methylanthraquinone","C034090","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1983,"6625663","The acute toxicity of 1-methylaminoanthraquinone in dogs and rabbits and its metabolism in sheep.","6625663",40]
["1-aminoanthracene","1-aminoanthracene","C049062","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15373829","Crystal structures of bovine odorant-binding protein in complex with odorant molecules.","15373829",40]
["1-aminoanthracene","1-aminoanthracene","C049062","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15979570","Odorant binding initially occurring at the central pocket in bovine odorant-binding protein.","15979570",40]
["1-aminobenzotriazole","1-aminobenzotriazole","C033020","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24550229","1-Aminobenzotriazole coincubated with (S)-warfarin results in potent inactivation of CYP2C9.","24550229",40]
["1-aminobenzotriazole","1-aminobenzotriazole","C033020","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9168258","Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.","9168258",40]
["1-aminobenzotriazole","1-aminobenzotriazole","C033020","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1992,"1409385","Inhibition of hepatic and cutaneous biotransformation of resorufin ethers following intraperitoneal administration of 1-aminobenzotriazole.","1409385",40]
["1-aminocyclopropanephosphonate","1-aminocyclopropanephosphonate","C053848","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3651390","1-Aminocyclopropanephosphonate: time-dependent inactivation of 1-aminocyclopropanecarboxylate deaminase and Bacillus stearothermophilus alanine racemase by slow dissociation behavior.","3651390",40]
["1-aminoindan","1-aminoindan","C016992","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25514361","Rasagiline, a suicide inhibitor of monoamine oxidases, binds reversibly to α-synuclein.","25514361",40]
["1-aminooxy-3-aminopropane","1-aminooxy-3-aminopropane","C046252","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17407445","A structural insight into the inhibition of human and Leishmania donovani ornithine decarboxylases by 1-amino-oxy-3-aminopropane.","17407445",40]
["1-aminooxy-4-((3-nitro-2-pyridyl)dithio)but-2-ene","1-aminooxy-4-((3-nitro-2-pyridyl)dithio)but-2-ene","C069106","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2095214","Synthesis of 1-(aminooxy)-4-[(3-nitro-2-pyridyl)dithio]butane and 1-(aminooxy)-4-[(3-nitro-2-pyridyl)dithio]but-2-ene, novel heterobifunctional cross-linking reagents.","2095214",40]
["1-aminopyrene","1-aminopyrene","C004482","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2005,"16708424","Ultraviolet radiation increases the toxicity of pyrene, 1-aminopyrene and 1-hydroxypyrene to human keratinocytes.","16708424",40]
["1-aminopyrene","1-aminopyrene","C004482","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8644108","Erythrocyte enzymes catalyze 1-nitropyrene and 3-nitrofluoranthene nitroreduction.","8644108",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10193192","1-anilino-8-naphthalene sulfonate as a protein conformational tightening agent.","10193192",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11322189","An electrospray ionization mass spectrometry investigation of 1-anilino-8-naphthalene-sulfonate (ANS) binding to proteins.","11322189",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12833479","Association of fluorescent probes 1-anilinonaphthalene-8-sulfonate and 4,4'-dianilino-1,1'-binaphthyl-5,5'-disulfonic acid with T7 RNA polymerase.","12833479",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1403732","Spectrofluorimetric study of the binding of 1-anilinonaphthalene-8-sulfonate to bovine serum albumin.","1403732",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14579352","Fluorescent dyes as probes to study lipid-binding proteins.","14579352",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14581221","Perturbation of protein tertiary structure in frozen solutions revealed by 1-anilino-8-naphthalene sulfonate fluorescence.","14581221",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14680830","cDNA cloning, expression, and mutagenesis of a PR-10 protein SPE-16 from the seeds of Pachyrrhizus erosus.","14680830",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1472032","Circular dichroic evidence for regulation of enzymatic activity by nonsubstrate hydrophobic ligand on glutathione S-transferase P.","1472032",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15081405","1,8-Anilinonaphthalene sulfonate binds to central cavity of human hemoglobin.","15081405",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15752696","The binding of 1,8 ANS congeners to I-FABP and comparison of some hypotheses about ANS' spectral sensitivity to environment.","15752696",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15752765","4,4'-Dianilino-1,1'-binaphthyl-5,5'-sulfonate, a novel molecule having chaperone-like activity.","15752765",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15769522","Quaternary association and reactivation of dimeric concanavalin A.","15769522",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16461396","ANS fluorescence detects widespread perturbations of protein tertiary structure in ice.","16461396",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16641488","Tunnel plasticity and quaternary structural integrity of a pentameric protein ring.","16641488",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16741984","Elucidating the binding thermodynamics of 8-anilino-1-naphthalene sulfonic acid with the A-state of alpha-lactalbumin: an isothermal titration calorimetric investigation.","16741984",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"16949725","Photophysics of ANS. III: Circular dichroism of ANS and anilinonaphthalene in I-FABP.","16949725",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16961435","Characterization of the interactions of fluorescent probes with proteins: coumarin 153 and 1,8-ANS in complex with holo- and apomyoglobin.","16961435",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"16978762","Photophysics of ANS. I. Protein-ANS complexes: Intestinal fatty acid binding protein and single-trp mutants.","16978762",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"16979813","Photophysics of ANS. V. Decay modes of ANS in proteins: the IFABP-ANS complex.","16979813",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17434452","Molten globule state of tear lipocalin: ANS binding restores tertiary interactions.","17434452",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1924140","Binding study of the fluorescence probe 1-anilino-8-naphthalensulfonate to human plasma and human and bovine serum albumin using potentiometric titration.","1924140",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19378188","A competition assay for DNA binding using the fluorescent probe ANS.","19378188",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19683079","Kinetics and thermodynamics of the interaction of 1-anilino-naphthalene-8-sulfonate with proteins.","19683079",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20025845","Selective binding of the fluorescent dye 1-anilinonaphthalene-8-sulfonic acid to peroxisome proliferator-activated receptor gamma allows ligand identification and characterization.","20025845",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2313585","Use of 1-anilino-8-naphthalene sulfonate as a fluorescent probe in the investigation of drug interactions with human alpha-1-acid glycoprotein and serum albumin.","2313585",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22829890","Reevaluation of ANS binding to human and bovine serum albumins: key role of equilibrium microdialysis in ligand - receptor binding characterization.","22829890",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22875404","Kinetics and thermodynamics of 1-anilino-8-naphthalene sulfonate interactions with Urinary Trypsin Inhibitor.","22875404",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24854592","Application of ANS fluorescent probes to identify hydrophobic sites on the surface of DREAM.","24854592",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25816771","Thermodynamic analysis of the disorder-to-α-helical transition of 18.5-kDa myelin basic protein reveals an equilibrium intermediate representing the most compact conformation.","25816771",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"2954553","Distances between the FITC-binding site in the (Ca2++Mg2+)-ATPase from sarcoplasmic reticulum and fluorescent probes located in the membrane.","2954553",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3365404","Energy-transfer studies of the distance between the high-affinity metal binding site and the colchicine and 8-anilino-1-naphthalenesulfonic acid binding sites on calf brain tubulin.","3365404",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3509976","The effects of the anilinonaphthalenesulfonates on the alkylation of tubulin: correlation between the appearance of sulfhydryl groups and apolar binding sites.","3509976",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3771101","Binding of 1-anilinonaphthalene-8-sulfonic acid to type I collagen.","3771101",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"3861197","Differential binding of the fluorescent probe 8-anilinonaphthalene-2-sulfonic acid to rhodanese catalytic intermediates.","3861197",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"6129102","Use of the fluorescent probe, 1-anilino-8-naphthalene sulfonate, to monitor the interaction of pesticide chemicals with mitochondrial membranes.","6129102",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6225641","Detection of conformational changes in chloroplast coupling factor 1 by 8-anilino-1-naphthalene-sulphonate fluorescence changes.","6225641",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1859,B1859)","v":"1-anilino-8-naphthalenesulfonate"},"1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1859,K1859)","v":"Protein Binding"},"D011485","Protein Binding",1,1,1984,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1859,Q1859)","v":"6548152"},"Specialized functional domains in hemoglobin: dimensions in solution of the apohemoglobin dimer labeled with fluorescein iodoacetamide.","6548152",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6714237","Interaction of native and modified Naja melanoleuca phospholipases A2 with the fluorescent probe 8-anilinonaphtalene-1-sulfonate.","6714237",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6726638","Use of the fluorescence probe 1-anilino-8-naphthalenesulfonate in predicting interindividual differences in the plasma protein binding of acidic drugs in rats.","6726638",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6870273","Binding of hydrophobic ligands to plant lectins: titration with arylaminonaphthalenesulfonates.","6870273",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"7115897","Properties of the complexes formed by 1-anilinonaphthalene-8-sulfonate with phosphorylase kinase and calmodulin.","7115897",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7197725","A spectrofluorometric investigation, using 1-anilino-naphthalene-8-sulphonate, of the interaction between washed bovine spermatozoa and seminal plasma or egg-yolk lipoprotein.","7197725",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7305408","The use of 1-anilino Naphthalene-8-sulfonate (ANS) for studying the effects of iodination on thyroglobulin conformation.","7305408",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1994,"7516732","Influence of the medium conditions on the 1-anilino-8-naphthalene sulfonate-bovine serum albumin binding.","7516732",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7702745","Energy transfer from tryptophan residues of proteins to 8-anilinonaphthalene-1-sulfonate.","7702745",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8004205","A competition assay for DNA binding using the fluorescent probe ANS.","8004205",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8099962","Use of 1-anilino-8-napthalenesulphonate as an ion probe for the potentiometric study of the binding of sulphonamides to bovine serum albumin and plasma.","8099962",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8645725","Effect of chaotropic denaturant on the binding of 1-anilino-8-naphthalene sulfonic acid to proteins.","8645725",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8770188","Characterization of the sources of protein-ligand affinity: 1-sulfonato-8-(1')anilinonaphthalene binding to intestinal fatty acid binding protein.","8770188",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8789718","A simple assay for intracellular lipid-binding proteins using displacement of 1-anilinonaphthalene 8-sulfonic acid.","8789718",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8804572","The essentiality of His-47 and the N-terminal region for the binding of 8-anilinonaphthalene-1-sulfonate with Taiwan cobra phospholipase A2.","8804572",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9057847","Binding of 1-anilinonaphthalene-8-sulfonic acid to alpha-crystallin.","9057847",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9449342","1-Anilino-8-naphthalene sulfonate anion-protein binding depends primarily on ion pair formation.","9449342",40]
["1-anilino-8-naphthalenesulfonate","1-anilino-8-naphthalenesulfonate","C027132","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9553072","Inhibition of assembly of bacterial cell division protein FtsZ by the hydrophobic dye 5,5'-bis-(8-anilino-1-naphthalenesulfonate).","9553072",40]
["1-arachidonyl monoglyceride","1-arachidonyl monoglyceride","C026433","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"17602815","Assessment of skin absorption and irritation potential of arachidonic acid and glyceryl arachidonate using in vitro diffusion cell techniques.","17602815",40]
["1-aza-7-benzyloxycarbonylamino-8-oxo-4-thiabicyclo(3.3.0)octane-2-carbonitrile","1-aza-7-benzyloxycarbonylamino-8-oxo-4-thiabicyclo(3.3.0)octane-2-carbonitrile","C545539","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19888757","Constrained peptidomimetics reveal detailed geometric requirements of covalent prolyl oligopeptidase inhibitors.","19888757",40]
["1-azafagomine","1-azafagomine","C414749","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"11828410","Direct NMR-spectroscopic determination of active-enzyme concentration by titration with a labeled inhibitor: determination of the k(cat) value of almond beta-glucosidase.","11828410",40]
["1-azidonaphthalene-5-sulfonate","1-azidonaphthalene-5-sulfonate","C022976","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6311257","Covalent modification of hydrophilic and hydrophobic domains of yeast cytochrome c oxidase with fluorescent azides.","6311257",40]
["1-benzilic-4,4'-quinuclidinyl benzilate","1-benzilic-4,4'-quinuclidinyl benzilate","C044493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1985,"2858352","Binding of N-[propionyl-3H]propionylated alpha-bungarotoxin and L-[benzilic-4,4'-3H] quinuclidinyl benzilate to CNS extracts of the cockroach Periplaneta americana.","2858352",40]
["1-benzoylethylpyridinium chloride","1-benzoylethylpyridinium chloride","C400243","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10488245","Inhibition of acetylcholinesterase by three new pyridinium compounds and their effect on phosphonylation of the enzyme.","10488245",40]
["1-benzoylethylpyridinium-4-aldoxime chloride","1-benzoylethylpyridinium-4-aldoxime chloride","C400244","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10488245","Inhibition of acetylcholinesterase by three new pyridinium compounds and their effect on phosphonylation of the enzyme.","10488245",40]
["1'-benzyl-3-(2-fluoroethyl)-3H-spiro((2)benzofuran-1,4'-piperidine)","1'-benzyl-3-(2-fluoroethyl)-3H-spiro((2)benzofuran-1,4'-piperidine)","C558383","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24130175","Synthesis, characterization, and metabolism studies of fluspidine enantiomers.","24130175",40]
["1-benzylimidazole","1-benzylimidazole","C017062","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16439365","Conformational flexibility of mammalian cytochrome P450 2B4 in binding imidazole inhibitors with different ring chemistry and side chains. Solution thermodynamics and molecular modeling.","16439365",40]
["1-benzyl-N-(2,6-dimethylphenyl)-3-pyrrolidine carboxamide","1-benzyl-N-(2,6-dimethylphenyl)-3-pyrrolidine carboxamide","C553457","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20580661","Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models.","20580661",40]
["1-benzyl-N-(3-(spiroisobenzofuran-1(3H),4'-piperidin-1-yl)propyl)pyrrolidine-2-carboxamide","1-benzyl-N-(3-(spiroisobenzofuran-1(3H),4'-piperidin-1-yl)propyl)pyrrolidine-2-carboxamide","C543193","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19527931","Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide.","19527931",40]
["1-benzylpiperidine","1-benzylpiperidine","C071293","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10425601","Automated docking of 82 N-benzylpiperidine derivatives to mouse acetylcholinesterase and comparative molecular field analysis with 'natural' alignment.","10425601",40]
["1-benzylpiperidine","1-benzylpiperidine","C071293","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"23078965","Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: synthesis, biological assessment, and molecular modeling.","23078965",40]
["1-benzylpiperidine","1-benzylpiperidine","C071293","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24745967","Benzylpiperidine variations on histamine H3 receptor ligands for improved drug-likeness.","24745967",40]
["1-biotinamido-4-(4'-(maleimidomethyl)cyclohexanecarboxamido)butane","1-biotinamido-4-(4'-(maleimidomethyl)cyclohexanecarboxamido)butane","C479840","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16411652","Cytosolic and nuclear protein targets of thiol-reactive electrophiles.","16411652",40]
["1-biotinamido-4-(4'-(maleimidomethyl)cyclohexanecarboxamido)butane","1-biotinamido-4-(4'-(maleimidomethyl)cyclohexanecarboxamido)butane","C479840","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"19548357","Reversibility of covalent electrophile-protein adducts and chemical toxicity.","19548357",40]
["1-biphenyl-4-methyl-1H-imidazole","1-biphenyl-4-methyl-1H-imidazole","C542154","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19397311","Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole: ligand-induced structural response through alpha-helical repositioning.","19397311",40]
["1-bromo-2,5-bis(4-hydroxystyryl)benzene","1-bromo-2,5-bis(4-hydroxystyryl)benzene","C507418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16313197","Mechanism of A beta(1-40) fibril-induced fluorescence of (trans,trans)-1-bromo-2,5-bis(4-hydroxystyryl)benzene (K114).","16313197",40]
["1-bromopinacolone","1-bromopinacolone","C036537","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2765553","Reactions of 1-bromo-2-[14C]pinacolone with acetylcholinesterase from Torpedo nobiliana. Effects of 5-trimethylammonio-2-pentanone and diisopropyl fluorophosphate.","2765553",40]
["1-bromopinacolone","1-bromopinacolone","C036537","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"7142196","1-Bromopinacolone, an active site-directed covalent inhibitor for acetylcholinesterase.","7142196",40]
["1-bromopropane","1-bromopropane","C118559","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12606292","Dose-dependent biochemical changes in rat central nervous system after 12-week exposure to 1-bromopropane.","12606292",40]
["1-Butanol","1-Butanol","D020001","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2005,"15652502","1-Butanol interferes with phospholipase D1 and protein kinase Calpha association and inhibits phospholipase D1 basal activity.","15652502",40]
["1-Butanol","1-Butanol","D020001","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22078843","Characterization of compounds and potential neuraminidase inhibitors from the n-butanol extract of Compound Indigowoad Root Granule using ultrafiltration and liquid chromatography-tandem mass spectrometry.","22078843",40]
["1-Butanol","1-Butanol","D020001","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"2905956","Plasma binding of 1-butanol, phenol, nitrobenzene and pentachlorophenol in the rainbow trout and rat: a comparative study.","2905956",40]
["1-Butanol","1-Butanol","D020001","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3488975","Radiation-induced binding of methanol, ethanol and 1-butanol to haemoglobin.","3488975",40]
["1-butyl-3-methylimidazolium chloride","1-butyl-3-methylimidazolium chloride","C502841","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2005,"15903191","Acute toxicity profile of 1-butyl-3-methylimidazolium chloride.","15903191",40]
["1-butyl-3-methylimidazolium chloride","1-butyl-3-methylimidazolium chloride","C502841","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23822219","Mediating electrostatic binding of 1-butyl-3-methylimidazolium chloride to enzyme surfaces improves conformational stability.","23822219",40]
["1-butyl-3-methylimidazolium chloride","1-butyl-3-methylimidazolium chloride","C502841","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2005,"15903191","Acute toxicity profile of 1-butyl-3-methylimidazolium chloride.","15903191",40]
["1-butyl-3-methylimidazolium hexafluorophosphate","1-butyl-3-methylimidazolium hexafluorophosphate","C412621","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23540249","Hyphenation of ionic liquid albumin glassy carbon biosensor or protein label-free sensor with differential pulse stripping voltammetry for interaction studies of human serum albumin with fenoprofen enantiomers.","23540249",40]
["1-butyl-3-methylimidazolium tetrafluoroborate","1-butyl-3-methylimidazolium tetrafluoroborate","C419324","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24721594","Deciphering the interaction of a model transport protein with a prototypical imidazolium room temperature ionic liquid: effect on the conformation and activity of the protein.","24721594",40]
["1-butyl-4-nitromethyl-3-quinolin-2-yl-4H-quinoline","1-butyl-4-nitromethyl-3-quinolin-2-yl-4H-quinoline","C584457","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23364515","Identification of a small-molecule inhibitor of bacterial AraC family activators.","23364515",40]
["1-butyl-4-nitromethyl-3-quinolin-2-yl-4H-quinoline","1-butyl-4-nitromethyl-3-quinolin-2-yl-4H-quinoline","C584457","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"24002059","Small-molecule inhibitor of the Shigella flexneri master virulence regulator VirF.","24002059",40]
["1-carba-1-deazariboflavin","1-carba-1-deazariboflavin","C015052","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11950835","Anabaena sp. PCC 7119 flavodoxin as electron carrier from photosystem I to ferredoxin-NADP+ reductase. Role of Trp(57) and Tyr(94).","11950835",40]
["1-carbapen-2-em-3-carboxylic acid","1-carbapen-2-em-3-carboxylic acid","C093704","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14625287","Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis.","14625287",40]
["1-chloro-2-ketohexanol-6-phosphate","1-chloro-2-ketohexanol-6-phosphate","C030195","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7225356","Synthesis of 1-chloro-2-oxohexanol 6-phosphate, a covalent active-site reagent for phosphoglucose isomerase.","7225356",40]
["1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene","1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene","C055238","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17487473","Comparative CYP-dependent binding of the adrenocortical toxicants 3-methylsulfonyl-DDE and o,p'-DDD in Y-1 adrenal cells.","17487473",40]
["1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene","1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene","C055238","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"2055367","Adrenocortical toxicity of 3-methylsulfonyl-DDE in mice. II. Mitochondrial changes following ecologically relevant doses.","2055367",40]
["1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene","1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene","C055238","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1988,"3345572","Metabolic activation and toxicity of a DDT-metabolite, 3-methylsulphonyl-DDE, in the adrenal zona fasciculata in mice.","3345572",40]
["1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene","1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene","C055238","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1994,"8171446","In vitro bioactivation of the environmental pollutant 3-methylsulphonyl-2, 2-bis(4-chlorophenyl)-1,1-dichloroethene in the human adrenal gland.","8171446",40]
["1-chloromethylpyrene","1-chloromethylpyrene","C052575","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1990,"2325693","1-Chloromethylpyrene: a reference skin sensitizer and genotoxin.","2325693",40]
["1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","C539237","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2009,"18992850","Effect of phosphodiesterase 7 inhibitor ASB16165 on development and function of cytotoxic T lymphocyte.","18992850",40]
["1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","C539237","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2009,"18992850","Effect of phosphodiesterase 7 inhibitor ASB16165 on development and function of cytotoxic T lymphocyte.","18992850",40]
["1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","C539237","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2009,"19379723","ASB16165, a phosphodiesterase 7A inhibitor, reduces cutaneous TNF-alpha level and ameliorates skin edema in phorbol ester 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation model in mice.","19379723",40]
["1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","C539237","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"20132810","Phosphodiesterase 7A inhibitor ASB16165 impairs proliferation of keratinocytes in vitro and in vivo.","20132810",40]
["1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","C539237","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2009,"19379723","ASB16165, a phosphodiesterase 7A inhibitor, reduces cutaneous TNF-alpha level and ameliorates skin edema in phorbol ester 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation model in mice.","19379723",40]
["1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","C539237","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20132810","Phosphodiesterase 7A inhibitor ASB16165 impairs proliferation of keratinocytes in vitro and in vivo.","20132810",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1923,B1923)","v":"1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide"},"1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide","C539237","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1923,K1923)","v":"T-Lymphocytes"},"D013601","T-Lymphocytes",1,3,2009,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1923,Q1923)","v":"19195485"},"ASB16165, a novel inhibitor for phosphodiesterase 7A (PDE7A), suppresses IL-12-induced IFN-gamma production by mouse activated T lymphocytes.","19195485",40]
["1-cyclopentyl-6-imidazol-1-yl-1h-benzoidazole-2-thiol-hydrochloride","1-cyclopentyl-6-imidazol-1-yl-1h-benzoidazole-2-thiol-hydrochloride","C495120","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15072922","Characterization of a new class of selective nonsteroidal progesterone receptor agonists.","15072922",40]
["1-decyl methyl sulfoxide","1-decyl methyl sulfoxide","C054274","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1988,"3373011","Hairless mouse skin is limited as a model for assessing the effects of penetration enhancers in human skin.","3373011",40]
["1-decylpyrrolidine-3,4-diol","1-decylpyrrolidine-3,4-diol","C000599730","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2014,"25445961","Iminosugar derivative WGN-26 suppresses acute allograft rejection via inhibiting the IFN-γ/p-STAT1/T-bet signaling pathway.","25445961",40]
["1-deoxygluco-heptulose 2-phosphate","1-deoxygluco-heptulose 2-phosphate","C044547","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2106586","Refined crystal structure of the phosphorylase-heptulose 2-phosphate-oligosaccharide-AMP complex.","2106586",40]
["1-deoxylulose 5-phosphate","1-deoxylulose 5-phosphate","C109460","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12269807","Multistate binding in pyridoxine 5'-phosphate synthase: 1.96 A crystal structure in complex with 1-deoxy-D-xylulose phosphate.","12269807",40]
["1-deoxylulose 5-phosphate","1-deoxylulose 5-phosphate","C109460","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15846973","Pools of 14C-malic acid as a substrate for pyruvate production for the DOXP/MEP pathway of biosynthesis of carotenoids in chloroplasts.","15846973",40]
["1-deoxylulose 5-phosphate","1-deoxylulose 5-phosphate","C109460","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1999,"10497868","Vgamma9/Vdelta2 T cell activation induced by bacterial low molecular mass compounds depends on the 1-deoxy-D-xylulose 5-phosphate pathway of isoprenoid biosynthesis.","10497868",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,2,1992,"1284982","The effect of glycosylation trimming enzyme inhibitors on monoclonal antibody recognition of alpha-sialoglycoprotein epitopes.","1284982",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2004,"15203163","Specific inhibition effects of N-pentafluorobenzyl-1-deoxynojirimycin on human CD4+ T cells.","15203163",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1991,"1678778","Effect of a glucosidase inhibitor on the bioactivity and immunoreactivity of human immunodeficiency virus type 1 envelope glycoprotein.","1678778",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2012,"22101135","An iminosugar N-pentafluorobenzyl-1-deoxynojirimycin as a novel potential immunosuppressant for the treatment of Th2-related diseases.","22101135",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1994,"7905523","The safety and efficacy of combination N-butyl-deoxynojirimycin (SC-48334) and zidovudine in patients with HIV-1 infection and 200-500 CD4 cells/mm3.","7905523",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1995,"8548334","The tolerability and pharmacokinetics of N-butyl-deoxynojirimycin in patients with advanced HIV disease (ACTG 100). The AIDS Clinical Trials Group (ACTG) of the National Institute of Allergy and Infectious Diseases.","8548334",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1997,"9143306","Recombinant HIV envelope expressed in an alpha-glucosidase I-deficient CHO cell line and its parental cell line in the presence of 1-deoxynojirimycin is functional.","9143306",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2014,"24390139","SERCA2 dysfunction in Darier disease causes endoplasmic reticulum stress and impaired cell-to-cell adhesion strength: rescue by Miglustat.","24390139",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2001,"11264342","Antiviral effect of N-butyldeoxynojirimycin against bovine viral diarrhea virus correlates with misfolding of E2 envelope proteins and impairment of their association into E1-E2 heterodimers.","11264342",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1475231","Distribution and elimination of the glycosidase inhibitors 1-deoxymannojirimycin and N-methyl-1-deoxynojirimycin in the rat in vivo.","1475231",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2006,"16546175","Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the alpha-glucosidase inhibitor miglustat.","16546175",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23303182","A novel transition-state analogue for lysozyme, 4-O-β-tri-N-acetylchitotriosyl moranoline, provided evidence supporting the covalent glycosyl-enzyme intermediate.","23303182",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23545138","(3R,4S,5R,6R,7S)-3,4,5,7-Tetrahydroxyconidine, an azetidine analogue of 6,7-diepicastanospermine and a conformationally constrained d-deoxyaltronojirimycin, from l-arabinose.","23545138",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24026016","Synthesis and biological evaluation of N-(2-fluorophenyl)-2β-deoxyfuconojirimycin acetamide as a potent inhibitor for α-l-fucosidases.","24026016",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24907709","Interaction of di-N-acetylchitobiosyl moranoline with a family GH19 chitinase from moss, Bryum coronatum.","24907709",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25708517","Design and application of a novel high-throughput screening technique for 1-deoxynojirimycin.","25708517",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8140045","Disposition of glycosidase inhibitors in the isolated perfused rat liver: hepatobiliary and subcellular concentration gradients of 1-deoxymannojirimycin and N-methyl-1-deoxynojirimycin.","8140045",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8988638","Steady-state kinetic and calorimetric studies on the binding of Aspergillus niger glucoamylase with gluconolactone, 1-deoxynojirimycin, and beta-cyclodextrin.","8988638",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23474038","A Phase 2 study of migalastat hydrochloride in females with Fabry disease: selection of population, safety and pharmacodynamic effects.","23474038",40]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2008,"18698230","Prediction of response of mutated alpha-galactosidase A to a pharmacological chaperone.","18698230",40]
["1-deoxy-nojirimycin","1-deoxy-nojirimycin","C478924","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25352425","Synthetic 1-deoxynojirimycin N-substituted peptides offer prolonged disruption to N-linked glycan processing.","25352425",40]
["1-dodecanoyl-sn-glycerophosphoethanolamine","1-dodecanoyl-sn-glycerophosphoethanolamine","C063390","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2157477","Complex formation of peptide antibiotic Ro09-0198 with lysophosphatidylethanolamine: 1H NMR analyses in dimethyl sulfoxide solution.","2157477",40]
["1-dodecyl glycidyl ether","1-dodecyl glycidyl ether","C414961","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"10875681","Dermal penetration and metabolism of five glycidyl ethers in human, rat and mouse skin.","10875681",40]
["1E7-03 compound","1E7-03 compound","C000598974","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"26801627","Protein Phosphatase-1 regulates Rift Valley fever virus replication.","26801627",40]
["1-epidechloroacutumine","1-epidechloroacutumine","C473531","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"12377240","Alkaloids from Menispermum dauricum.","12377240",40]
["1-ethoxysilatrane","1-ethoxysilatrane","C042292","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1986,"2940364","Effect of haemorrhage on wound healing and its possible modification by 1-ethoxysilatrane.","2940364",40]
["1-ethyl-2-benzimidazolinone","1-ethyl-2-benzimidazolinone","C102635","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2003,"12421833","Unexpected down-regulation of the hIK1 Ca2+-activated K+ channel by its opener 1-ethyl-2-benzimidazolinone in HaCaT keratinocytes. Inverse effects on cell growth and proliferation.","12421833",40]
["1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide methiodide","1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide methiodide","C041829","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3964300","Binding of DNA to albumin and transferrin modified by treatment with water-soluble carbodiimides.","3964300",40]
["1-ethyl-3-(3-dimethylaminoethyl)carbodiimide","1-ethyl-3-(3-dimethylaminoethyl)carbodiimide","C074139","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7758805","The importance of acidic amino acid residues in the binding of ligands to the V1a vasopressin receptor.","7758805",40]
["1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-","1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-","C044846","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21689106","SKF-83566, a D1-dopamine receptor antagonist, inhibits the dopamine transporter.","21689106",40]
["1-hexadecyl-2-acetyl-glycero-3-phosphocholine","1-hexadecyl-2-acetyl-glycero-3-phosphocholine","C037145","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"20041255","Platelet activating factor stimulates arachidonic acid release in differentiated keratinocytes via arachidonyl non-selective phospholipase A2.","20041255",40]
["1-hexanol","1-hexanol","C036260","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2004,"15160491","Modulation of actomyosin motor function by 1-hexanol.","15160491",40]
["1-hexylindolactam-V10","1-hexylindolactam-V10","C526800","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18072722","Synthesis, conformational analysis, and biological evaluation of 1-hexylindolactam-V10 as a selective activator for novel protein kinase C isozymes.","18072722",40]
["1-hexylthio-2-nonanoylamino-1,2-dideoxy-sn-glycero-3-phosphocholine","1-hexylthio-2-nonanoylamino-1,2-dideoxy-sn-glycero-3-phosphocholine","C093009","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7711016","Conformation of micellar phospholipid bound to the active site of phospholipase A2.","7711016",40]
["1H-indole-2-carboxylic acid (4-(2-(cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl)cyclohexyl)amide","1H-indole-2-carboxylic acid (4-(2-(cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl)cyclohexyl)amide","C553924","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2018,"29337986","The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors.","29337986",40]
["1H-indole-3-carbaldehyde quinolin-8-yl-hydrazone","1H-indole-3-carbaldehyde quinolin-8-yl-hydrazone","C571887","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22245285","Human T cell expansion and experimental autoimmune encephalomyelitis inhibited by Lenaldekar, a small molecule discovered in a zebrafish screen.","22245285",40]
["1H-indole-3-carbaldehyde quinolin-8-yl-hydrazone","1H-indole-3-carbaldehyde quinolin-8-yl-hydrazone","C571887","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22490804","Zebrafish screen identifies novel compound with selective toxicity against leukemia.","22490804",40]
["1H-indole-3-carbaldehyde quinolin-8-yl-hydrazone","1H-indole-3-carbaldehyde quinolin-8-yl-hydrazone","C571887","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2014,"24718491","Targeting insulin-like growth factor 1 leads to amelioration of inflammatory demyelinating disease.","24718491",40]
["1H-tetrazole","1H-tetrazole","C045574","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21536435","Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X(7) antagonists.","21536435",40]
["1H-tetrazole","1H-tetrazole","C045574","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23414805","Chemical tagging of a drug target using 5-sulfonyl tetrazole.","23414805",40]
["1H-tetrazole","1H-tetrazole","C045574","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23414808","Synthesis of tetrazole analogues of phosphonohydroxamic acids: an attempt to improve the inhibitory activity against the DXR.","23414808",40]
["1H-tetrazole","1H-tetrazole","C045574","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8397193","Specific modification of structure and property of myoglobin by the formation of tetrazolylhistidine 64(E7). Reaction of the modified myoglobin with molecular oxygen.","8397193",40]
["1-hydroxy-19-norvitamin D3","1-hydroxy-19-norvitamin D3","C114865","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26232635","Synthesis, metabolism, and biological activity of 2-[3-(tetrazolyl)propyl]-1α,25-dihydroxy-19-norvitamin D3.","26232635",40]
["1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene","1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene","C105351","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2002,"12427017","Nitric oxide-mediated inhibition of Hdm2-p53 binding.","12427017",40]
["1-hydroxyalantolactone","1-hydroxyalantolactone","C000599362","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,2,2016,"26017682","1β-Hydroxyalantolactone, a sesquiterpene lactone from Inula japonica, attenuates atopic dermatitis-like skin lesions induced by 2,4-dinitrochlorobenzene in the mouse.","26017682",40]
["1-hydroxyalantolactone","1-hydroxyalantolactone","C000599362","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25200604","A sesquiterpene lactone from a medicinal herb inhibits proinflammatory activity of TNF-α by inhibiting ubiquitin-conjugating enzyme UbcH5.","25200604",40]
["1-hydroxyethyl radical","1-hydroxyethyl radical","C065424","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11473574","Protein adducts in type I and type II fibre predominant muscles of the ethanol-fed rat: preferential localisation in the sarcolemmal and subsarcolemmal region.","11473574",40]
["1-hydroxyethyl radical","1-hydroxyethyl radical","C065424","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11781504","Protein binding of alpha-hydroxyethyl free radicals.","11781504",40]
["1-hydroxyethyl radical","1-hydroxyethyl radical","C065424","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11796198","Free radical mechanisms in immune reactions associated with alcoholic liver disease.","11796198",40]
["1-hydroxymethyl-3-norhydroxy-3,25-dihydroxyvitamin D3","1-hydroxymethyl-3-norhydroxy-3,25-dihydroxyvitamin D3","C076211","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1992,"1324319","New vitamin D3 derivatives with unexpected antiproliferative activity: 1-(hydroxymethyl)-25-hydroxyvitamin D3 homologs.","1324319",40]
["1-hydroxymethylmidazolam","1-hydroxymethylmidazolam","C040081","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10215689","Characterization of the pharmacodynamic interaction between parent drug and active metabolite in vivo: midazolam and alpha-OH-midazolam.","10215689",40]
["1-hydroxymethylmidazolam","1-hydroxymethylmidazolam","C040081","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10215698","Midazolam metabolism by modified Caco-2 monolayers: effects of extracellular protein binding.","10215698",40]
["1-hydroxymethylmidazolam","1-hydroxymethylmidazolam","C040081","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21992114","The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4.","21992114",40]
["1-hydroxymethylmidazolam","1-hydroxymethylmidazolam","C040081","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8646820","Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.","8646820",40]
["1-hydroxymethylmidazolam glucuronide","1-hydroxymethylmidazolam glucuronide","C061795","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2582710","Decreased plasma albumin concentration results in increased volume of distribution and decreased elimination of midazolam in intensive care patients.","2582710",40]
["1-hydroxypyrene","1-hydroxypyrene","C033146","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2005,"16001207","Dermal and bronchial symptoms in children: are they caused by PAH containing parquet glue or by passive smoking?","16001207",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1987,B1987)","v":"1-hydroxypyrene"},"1-hydroxypyrene","C033146","2_KE",826,2,"Keratinocytes","Activation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1987,K1987)","v":"Keratinocytes"},"D015603","Keratinocytes",1,3,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1987,Q1987)","v":"16708424"},"Ultraviolet radiation increases the toxicity of pyrene, 1-aminopyrene and 1-hydroxypyrene to human keratinocytes.","16708424",40]
["1-hydroxypyrene","1-hydroxypyrene","C033146","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14749914","Correlation between biomarkers of polycyclic aromatic hydrocarbon exposure and electrophilic tissue burden in a rat model.","14749914",40]
["1-hydroxypyrene","1-hydroxypyrene","C033146","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1986,"3726495","Biological monitoring of polycyclic aromatic hydrocarbons. Metabolites in urine.","3726495",40]
["1-hydroxyvitamin D5","1-hydroxyvitamin D5","C103958","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14712498","Effect of vitamin D analog (1alpha hydroxy D5) immunoconjugated to Her-2 antibody on breast cancer.","14712498",40]
["1-isopropyl-5-(1-(2-(2-methylpyrrolidin-1-yl)ethyl)-1H-indol-4-yl)pyridin-2(1H)-one","1-isopropyl-5-(1-(2-(2-methylpyrrolidin-1-yl)ethyl)-1H-indol-4-yl)pyridin-2(1H)-one","C000601545","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25394333","From ergolines to indoles: improved inhibitors of the human H3 receptor for the treatment of narcolepsy.","25394333",40]
["1-isopropyloxygenipin","1-isopropyloxygenipin","C569486","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20118574","Neuritogenic activities of 1-alkyloxygenipins.","20118574",40]
["1-kestose","1-kestose","C072433","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2013,"23218283","Structure and protective effect on UVB-induced keratinocyte damage of fructan from white garlic.","23218283",40]
["1-kestose","1-kestose","C072433","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22098191","Crystal structure of 6-SST/6-SFT from Pachysandra terminalis, a plant fructan biosynthesizing enzyme in complex with its acceptor substrate 6-kestose.","22098191",40]
["1-kestose","1-kestose","C072433","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26956120","Functional analysis of the binding model of microbial inulinases using docking and molecular dynamics simulation.","26956120",40]
["1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate","1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate","C477931","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14570904","Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3'-OH kinase-Akt pathway.","14570904",40]
["1-menthene","1-menthene","C048063","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"3234846","[Toxicologic properties and the nature of the combined effect of a orthomenthane hydrocarbon mixture].","3234846",40]
["1-methoxy-5-methylphenazinium methyl sulfate","1-methoxy-5-methylphenazinium methyl sulfate","C023530","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2002,"12184917","A new assay system for guinea pig interferon biological activity.","12184917",40]
["1-methyl-1,2,3,4-tetrahydroisoquinoline","1-methyl-1,2,3,4-tetrahydroisoquinoline","C050386","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2006,"16515537","The mechanism of 1,2,3,4-tetrahydroisoquinolines neuroprotection: the importance of free radicals scavenging properties and inhibition of glutamate-induced excitotoxicity.","16515537",40]
["1-methyl-1H-indole-2-carboxylic acid (4-(1-(4-(4-acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo(3,4-d)pyrimidin-3-yl)-2-methoxyphenyl)amide","1-methyl-1H-indole-2-carboxylic acid (4-(1-(4-(4-acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo(3,4-d)pyrimidin-3-yl)-2-methoxyphenyl)amide","C505452","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2005,"16014572","A-770041, a novel and selective small-molecule inhibitor of Lck, prevents heart allograft rejection.","16014572",40]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15893609","A role of IL-1 in MPTP-induced changes in striatal dopaminergic and serotoninergic transporter binding: clues from interleukin-1 type I receptor-deficient mice.","15893609",40]
["1-naphthol","1-naphthol","C029350","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3336003","Conjugative clearance of 1-naphthol and disposition of its glucuronide and sulfate conjugates in the isolated perfused rat kidney.","3336003",40]
["1-O-hexadecyl-2-N-methylcarbamol -sn-glycerol-3-phosphocholine","1-O-hexadecyl-2-N-methylcarbamol -sn-glycerol-3-phosphocholine","C083283","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2005,"16184199","Staphylococcal lipoteichoic acid inhibits delayed-type hypersensitivity reactions via the platelet-activating factor receptor.","16184199",40]
["1-pentanoyl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)pyrrolidine-2-carboxamide","1-pentanoyl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)pyrrolidine-2-carboxamide","C571002","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21713967","1-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-pyrrolidine-2-carboxamide: investigation of structural variations.","21713967",40]
["1-Propanol","1-Propanol","D000433","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1988,"3342628","Contamination reduction during central venous catheterization.","3342628",40]
["2-(2-(5-nitro-2-thienyl)vinyl)quinoline","2-(2-(5-nitro-2-thienyl)vinyl)quinoline","C585478","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2013,"23945945","Characterization of novel inhibitors of HIV-1 replication that function via alteration of viral RNA processing and rev function.","23945945",40]
["2-(2-hydroxybiphenyl-4-yl)propanoic acid","2-(2-hydroxybiphenyl-4-yl)propanoic acid","C581359","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"23205941","Intraprotein formation of a long wavelength absorbing complex and inhibition of excited-state deprotonation in a chiral hydroxybiphenyl.","23205941",40]
["2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxylic acid amide","2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxylic acid amide","C500066","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2005,"15771432","Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazoles.","15771432",40]
["2-(alpha-(2-fluoromethoxyphenoxy)benzyl)morpholine","2-(alpha-(2-fluoromethoxyphenoxy)benzyl)morpholine","C506462","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"20309528","Norepinephrine transporter occupancy by antidepressant in human brain using positron emission tomography with (S,S)-[18F]FMeNER-D2.","20309528",40]
["2,2,2-trichloroethanol","2,2,2-trichloroethanol","C005849","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12856888","Binding of the general anesthetics chloroform and 2,2,2-trichloroethanol to the hydrophobic core of a four-alpha-helix bundle proteins.","12856888",40]
["2,2'-Dipyridyl","2,2'-Dipyridyl","D015082","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22385827","Protein recognition of hetero-/homoleptic ruthenium(II) tris(bipyridine)s for α-chymotrypsin and cytochrome c.","22385827",40]
["2,2'-methylene-bis-(6-(2H-benzotriazole-2-yl))-4-(1,1,3,3-tetramethylbutyl)phenol","2,2'-methylene-bis-(6-(2H-benzotriazole-2-yl))-4-(1,1,3,3-tetramethylbutyl)phenol","C510891","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21692815","Surface distribution and depths profiling of particulate organic UV absorbers by Raman imaging and tape stripping.","21692815",40]
["2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone","2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone","C060262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2004,"15005624","Quinones facilitate the self-assembly of the phosphorylated tubulin binding region of tau into fibrillar polymers.","15005624",40]
["2,4-D amine","2,4-D amine","C037991","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1992,"1629935","Dermal absorption of the phenoxy herbicide 2,4-D dimethylamine in humans: effect of DEET and anatomic site.","1629935",40]
["2,4-Dichlorophenoxyacetic Acid","2,4-Dichlorophenoxyacetic Acid","D015084","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"20383622","Adverse effects of 2,4-dichlorophenoxyacetic acid on rat cerebellar granule cell cultures were attenuated by amphetamine.","20383622",40]
["2,5-diaminotoluene","2,5-diaminotoluene","C007303","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2017,"27555055","Two decades of p-phenylenediamine and toluene-2,5-diamine patch testing - focus on co-sensitizations in the European baseline series and cross-reactions with chemically related substances.","27555055",40]
["2,6-Dichloroindophenol","2,6-Dichloroindophenol","D015086","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"856300","[Study of the kinetic mechanism of the pyruvate-2,6-dichlorophenolindophenol reductase activity of muscle pyruvate dehydrogenase].","856300",40]
["24,25-Dihydroxyvitamin D 3","24,25-Dihydroxyvitamin D 3","D015650","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6604593","24,25-dihydroxyvitamin D3 in serum: sample purification with Sep-Pak C-18 cartridges and liquid chromatography before protein-binding assay.","6604593",40]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"20684184","The role of vitamin D in regulating immune responses.","20684184",40]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"23092798","Analytical evaluation of a new automated protein binding assay to determine 25-hydroxyvitamin D concentrations.","23092798",40]
["2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine","2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine","C049584","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7586200","DNA-binding and disposition of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in the rat.","7586200",40]
["2-amino-4-(3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo(5,4-b)pyridin-2-yl)phenyl)-2-methylbutanoic acid","2-amino-4-(3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo(5,4-b)pyridin-2-yl)phenyl)-2-methylbutanoic acid","C572311","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"22257889","Isoform-selective thiazolo[5,4-b]pyridine S1P1 agonists possessing acyclic amino carboxylate head-groups.","22257889",40]
["2beta-carbomethoxy-3beta-(4-iodophenyl)tropane","2beta-carbomethoxy-3beta-(4-iodophenyl)tropane","C069723","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10459174","Comparative in vivo study of iodine-123-labeled beta-CIT and nor-beta-CIT binding to serotonin transporters in rat brain.","10459174",40]
["2-chloranil","2-chloranil","C039499","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6635333","In vitro binding of 3,4,5,6-tetrachloro-1,2-benzoquinone by rat liver glutathione S-transferases.","6635333",40]
["2-deoxy-2,3-dehydro-N-acetylneuraminic acid","2-deoxy-2,3-dehydro-N-acetylneuraminic acid","C036137","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16647045","Insights from modeling the 3D structure of H5N1 influenza virus neuraminidase and its binding interactions with ligands.","16647045",40]
["2-ethylhexyl acrylate","2-ethylhexyl acrylate","C036758","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20001660","The potential dermal irritating effect of residual (meth)acrylic monomers in pressure sensitive adhesive tapes.","20001660",40]
["2-heptyl-4-quinolone","2-heptyl-4-quinolone","C528166","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26811339","PqsBC, a Condensing Enzyme in the Biosynthesis of the Pseudomonas aeruginosa Quinolone Signal: CRYSTAL STRUCTURE, INHIBITION, AND REACTION MECHANISM.","26811339",40]
["2-iodonisoxetine","2-iodonisoxetine","C493911","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15219270","Selective binding of 2-[125I]iodo-nisoxetine to norepinephrine transporters in the brain.","15219270",40]
["2'-methoxykurarinone","2'-methoxykurarinone","C411318","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"20883179","(2S)-2′-methoxykurarinone from Sophora flavescens suppresses cutaneous T cell-attracting chemokine/CCL27 expression induced by interleukin-ß/tumor necrosis factor-α via heme oxygenase-1 in human keratinocytes.","20883179",40]
["2-methyl-4-isothiazolin-3-one","2-methyl-4-isothiazolin-3-one","C011506","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2014,"24679904","Descriptive study of sensitization to methylchloroisothiazolinone and methylisothiazolinone in a skin allergy unit.","24679904",40]
["2-methyl-4-isothiazolin-3-one","2-methyl-4-isothiazolin-3-one","C011506","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2016,"27538353","Octylisothiazolinone, an additional cause of allergic contact dermatitis caused by leather: case series and potential implications for the study of cross-reactivity with methylisothiazolinone.","27538353",40]
["2-methyl-4-isothiazolin-3-one","2-methyl-4-isothiazolin-3-one","C011506","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2003,"12880425","Involvement of oxidative stress in apoptosis induced by a mixture of isothiazolinones in normal human keratinocytes.","12880425",40]
["2-nitronaphthalene","2-nitronaphthalene","C048317","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"16797226","Induction of LacZ mutations in Muta Mouse can distinguish carcinogenic from non-carcinogenic analogues of diaminotoluenes and nitronaphthalenes.","16797226",40]
["2-oxindole","2-oxindole","C022960","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"25808617","Computational analysis of spiro-oxindole inhibitors of the MDM2-p53 interaction: insights and selection of novel inhibitors.","25808617",40]
["2-phenylquinazoline","2-phenylquinazoline","C516488","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"23017888","4-Substituted-2-phenylquinazolines as inhibitors of BCRP.","23017888",40]
["3-((2'-hydroxy-4'-iodobenzoyl)oxy)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid isopropyl ester","3-((2'-hydroxy-4'-iodobenzoyl)oxy)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid isopropyl ester","C112872","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1998,"9632371","2beta-Substituted analogues of 4'-iodococaine: synthesis and dopamine transporter binding potencies.","9632371",40]
["3-(2,2,2-trimethylhydrazine)propionate","3-(2,2,2-trimethylhydrazine)propionate","C050147","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18273902","Interaction of mildronate with the mitochondrial carnitine/acylcarnitine transport protein.","18273902",40]
["3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole","3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole","C090937","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2007,"17673145","Modulation of human monocyte-derived dendritic cells maturation by a soluble guanylate cyclase activator, YC-1, in a cyclic nucleotide independent manner.","17673145",40]
["3,3-(ethylenedioxy)-eudesmano-13,6-diacetate","3,3-(ethylenedioxy)-eudesmano-13,6-diacetate","C511609","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2006,"16554308","Chemical modification of santonin into a diacetoxy acetal form confers the ability to induce differentiation of human promyelocytic leukemia cells via the down-regulation of NF-kappaB DNA binding activity.","16554308",40]
["3,4-dicarbethoxyhexane-2,5-dione","3,4-dicarbethoxyhexane-2,5-dione","C065728","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1990,"2144809","Contact allergy to 3,4-dicarbethoxyhexane-2,5-dione.","2144809",40]
["3,4-dihydroxyphenyllactic acid","3,4-dihydroxyphenyllactic acid","C035055","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24528010","Identification of a potential anticancer target of danshensu by inverse docking.","24528010",40]
["3,5-dimethoxy-4'-hydroxystilbene","3,5-dimethoxy-4'-hydroxystilbene","C506282","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15773817","Inhibition of mammalian DNA polymerases by resveratrol: mechanism and structural determinants.","15773817",40]
["3-azido-2,7-naphthalene disulfonate","3-azido-2,7-naphthalene disulfonate","C019152","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6311257","Covalent modification of hydrophilic and hydrophobic domains of yeast cytochrome c oxidase with fluorescent azides.","6311257",40]
["3-carboxy-4-methyl-5-propyl-2-furanpropionic acid","3-carboxy-4-methyl-5-propyl-2-furanpropionic acid","C041693","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8671898","Retention of an albumin-bound furan dicarboxylic acid in patients with chronic renal failure or after a kidney transplant.","8671898",40]
["3-Hydroxyanthranilic Acid","3-Hydroxyanthranilic Acid","D015095","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2006,"16385630","Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines.","16385630",40]
["3-hydroxyleukotriene B4","3-hydroxyleukotriene B4","C090952","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1995,"8548366","3(S)-hydroxy-leukotriene B4 is a potent granulocyte chemotaxin in the guinea pig dermis.","8548366",40]
["3-iodo-2-hydroxy-6-methoxy-N-((1-ethyl-2-pyrrolidinyl)methyl)benzamide","3-iodo-2-hydroxy-6-methoxy-N-((1-ethyl-2-pyrrolidinyl)methyl)benzamide","C055743","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19683898","Increase of striatal dopamine transmission in first episode drug-naive schizophrenic patients as demonstrated by [(123)I]IBZM SPECT.","19683898",40]
["3-nitrosobenzamide","3-nitrosobenzamide","C076039","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"7527151","Comparison of the cytotoxic and antiretroviral effects of 3-nitrosobenzamide and 4-iodo-3-nitrobenzamide.","7527151",40]
["3-phenylpropyl acetate","3-phenylpropyl acetate","C577735","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22414651","Fragrance material review on 3-phenylpropyl acetate.","22414651",40]
["4-(2-mercaptophenylcarboxamido)benzenesulfonamide","4-(2-mercaptophenylcarboxamido)benzenesulfonamide","C514064","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16942027","Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX.","16942027",40]
["4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone","4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone","D012368","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1985,"3998494","Phosphodiesterase inhibition by Ro 20-1724 reduces hyper-IgE synthesis by atopic dermatitis cells in vitro.","3998494",40]
["4-(hydroxymethyl)colchicine","4-(hydroxymethyl)colchicine","C043919","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6094813","Synthesis and binding to tubulin of colchicine spin probes.","6094813",40]
["4,4'-diaminodiphenylmethane","4,4'-diaminodiphenylmethane","C009505","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"7634786","Sensitivity to diaminodiphenylmethane.","7634786",40]
["4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-geldanamycin","4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-geldanamycin","C523490","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17662999","Mechanistic studies on Hsp90 inhibition by ansamycin derivatives.","17662999",40]
["4,5-dibromorhodamine 123","4,5-dibromorhodamine 123","C121365","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2008,"18381757","Pro-tolerogenic effects of photodynamic therapy with TH9402 on dendritic cells.","18381757",40]
["4,7-dichloroquinoline","4,7-dichloroquinoline","C035317","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1982,"6213361","Allergic contact dermatitis from 4,7-dichloroquinoline.","6213361",40]
["4-Aminobenzoic Acid","4-Aminobenzoic Acid","D010129","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"6126158","Modification of the acceptor binding site of gamma-glutamyl transpeptidase by the diazonium derivatives of p-aminohippurate and p-aminobenzoate.","6126158",40]
["4-Aminopyridine","4-Aminopyridine","D015761","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"7075108","4-Aminopyridine kinetics.","7075108",40]
["4-benzoylpyridine","4-benzoylpyridine","C066738","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"23656552","Comparative inhibition of tetrameric carbonyl reductase activity in pig heart cytosol by alkyl 4-pyridyl ketones.","23656552",40]
["4-chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester","4-chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester","C527120","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2008,"18186753","Allergic contact dermatitis from 4-chloro-2-[methylthio]pyrimidine-5-carboxylic acid ethyl ester and methyl 4-hydroxy-2-hexynoate in a laboratory chemist.","18186753",40]
["4-chloromethylbiphenyl","4-chloromethylbiphenyl","C033487","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1982,"7057779","Activity of 4CMB in the mouse-skin sebaceous-gland suppression test.","7057779",40]
["4-ethoxymethylene-2-phenyl-2-oxazoline-5-one","4-ethoxymethylene-2-phenyl-2-oxazoline-5-one","C119678","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2006,"16814963","17beta-estradiol enhances contact hypersensitivity and IFN-gamma expression in inflamed skin of BALB/c mice.","16814963",40]
["4-hydroxy-2-nonenal","4-hydroxy-2-nonenal","C027576","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16451125","Synergy of fatty acid and reactive alkenal activation of proton conductance through uncoupling protein 1 in mitochondria.","16451125",40]
["4-hydroxy-2-nonenal","4-hydroxy-2-nonenal","C027576","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1984,"6548938","The mechanism of action of 4-hydroxynonenal in cell injury.","6548938",40]
["4-hydroxyphenylprinomide","4-hydroxyphenylprinomide","C079526","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8430060","Prinomide tromethamine pharmacokinetics: mutually dependent saturable and competitive protein binding between prinomide and its own metabolite.","8430060",40]
["4-isopropyldibenzoylmethane","4-isopropyldibenzoylmethane","C049936","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1990,"2150650","[Photoallergic contact eczema caused by 4-isopropyldibenzoylmethane].","2150650",40]
["4-methylumbelliferyl-N-acetylchitotetraoside","4-methylumbelliferyl-N-acetylchitotetraoside","C027049","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7275944","Hydrolysis of 4-methylumbelliferyl N-acetyl-chitooligosaccharides catalyzed by human lysozyme.","7275944",40]
["4-nitrophenylgalactoside","4-nitrophenylgalactoside","C059200","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2271705","Binding of p-nitrophenyl alpha-D-galactopyranoside to lac permease of Escherichia coli.","2271705",40]
["4-O-methyl-12-O-tetradecanoylphorbol 13-acetate","4-O-methyl-12-O-tetradecanoylphorbol 13-acetate","C020922","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1987,"3117560","Tumor-promoting phorbol esters cause a stable reduction of dermal collagen in mouse skin.","3117560",40]
["4-phenylenediamine","4-phenylenediamine","C029728","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2006,"17014438","p-Phenylenediamine allergy: the role of Bandrowski's base.","17014438",40]
["4-phenylenediamine","4-phenylenediamine","C029728","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2011,"21469591","The association between prolonged occupational exposure to paraphenylenediamine (hair-dye) and renal impairment.","21469591",40]
["4-phenylenediamine","4-phenylenediamine","C029728","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1996,"8930490","Contact anaphylaxis due to para-phenylenediamine.","8930490",40]
["4-phenylenediamine","4-phenylenediamine","C029728","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"12063532","Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones.","12063532",40]
["4-xylene","4-xylene","C031286","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27070865","Binding Energy Distribution Analysis Method: Hamiltonian Replica Exchange with Torsional Flattening for Binding Mode Prediction and Binding Free Energy Estimation.","27070865",40]
["5-(6)-carboxyfluorescein diacetate succinimidyl ester","5-(6)-carboxyfluorescein diacetate succinimidyl ester","C087165","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2001,"11238628","Human vascular endothelial cells stimulate a lower frequency of alloreactive CD8+ pre-CTL and induce less clonal expansion than matching B lymphoblastoid cells: development of a novel limiting dilution analysis method based on CFSE labeling of lymphocytes.","11238628",40]
["5-(ethylpropyl)amiloride","5-(ethylpropyl)amiloride","C043988","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2549314","Methyl isobutyl amiloride: a new probe to assess the number of Na-H antiporters.","2549314",40]
["5,8,11,14-Eicosatetraynoic Acid","5,8,11,14-Eicosatetraynoic Acid","D015117","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1994,"7881868","Reduced drug resistance in a multidrug resistant cell line by 5,8,11,14-eicosatetraynoic acid.","7881868",40]
["5-acetylneuraminyl-2-3-galactosyl-1-3-(fucopyranosyl-1-4)-N-acetylglucosamine","5-acetylneuraminyl-2-3-galactosyl-1-3-(fucopyranosyl-1-4)-N-acetylglucosamine","C086528","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10452802","Selectin/glycoconjugate binding assays for the identification and optimization of selectin antagonists.","10452802",40]
["5-aminoisatin","5-aminoisatin","C459159","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"16119092","[Glycerol-3-phosphate dehydrogenase--cytosolic isatin-binding protein].","16119092",40]
["5-chloro-2-methyl-4-isothiazolin-3-one","5-chloro-2-methyl-4-isothiazolin-3-one","C011421","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2016,"26536492","Patch Testing for Methylisothiazolinone and Methylchloroisothiazolinone-Methylisothiazolinone Contact Allergy.","26536492",40]
["5-chloro-2-methyl-4-isothiazolin-3-one","5-chloro-2-methyl-4-isothiazolin-3-one","C011421","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"25395006","Assessment of the sensitizing potency of preservatives with chance of skin contact by the loose-fit coculture-based sensitization assay (LCSA).","25395006",40]
["5-hydroxymethyluracil","5-hydroxymethyluracil","C008055","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8764400","On the connection between inherent DNA flexure and preferred binding of hydroxymethyluracil-containing DNA by the type II DNA-binding protein TF1.","8764400",40]
["5-isobutylnaphthalene-1-acetic acid","5-isobutylnaphthalene-1-acetic acid","C060743","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2633918","Pharmacokinetics and metabolism of 14C isobytylnaphtyl acetic acid in rat.","2633918",40]
["5-thio-D-glucose","5-thio-D-glucose","C003002","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"10209867","The use of fluoro- and deoxy-substrate analogs to examine binding specificity and catalysis in the enzymes of the sorbitol pathway.","10209867",40]
["6-(3-methyl-1H-pyrazol-4-yl)-2-(pyrrolidin-1-ylmethyl)thieno(3,2-d)pyrimidin-4(3H)-one","6-(3-methyl-1H-pyrazol-4-yl)-2-(pyrrolidin-1-ylmethyl)thieno(3,2-d)pyrimidin-4(3H)-one","C000622935","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28533114","2-Aminomethylthieno[3,2-d]pyrimidin-4(3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase.","28533114",40]
["6,7-dihydroxyflavone","6,7-dihydroxyflavone","C485383","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25143381","Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor.","25143381",40]
["6-hydroxyflavone","6-hydroxyflavone","C529356","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"29102848","Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses.","29102848",40]
["6-methyl-2-ethyl-3-hydroxypyridine","6-methyl-2-ethyl-3-hydroxypyridine","C009820","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6836956","[Effect of the antioxidant OP-6 on some model reactions of the blood coagulation system].","6836956",40]
["7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2H-1-benzopyran-2-propanoic acid","7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2H-1-benzopyran-2-propanoic acid","C082206","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1993,"8392493","Leukotriene B4-induced granulocyte trafficking in guinea pig dermis. Effect of second-generation leukotriene B4 receptor antagonists, SC-50605 and SC-51146.","8392493",40]
["7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide","7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide","D015123","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1993,"8284318","Fluorescence line-narrowing studies of antibody-benzo[a]pyrene tetrol complexes.","8284318",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8259,B8259)","v":"7-carboxynalidixic acid"},"7-carboxynalidixic acid","C025188","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J8259,K8259)","v":"Protein Binding"},"D011485","Protein Binding",1,1,1988,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q8259,Q8259)","v":"3205675"},"Pharmacokinetics of nalidixic acid in man: hydroxylation and glucuronidation.","3205675",40]
["7-hydroxyamoxapine","7-hydroxyamoxapine","C041917","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24780296","Old drug new use--amoxapine and its metabolites as potent bacterial β-glucuronidase inhibitors for alleviating cancer drug toxicity.","24780296",40]
["7-hydroxystaurosporine","7-hydroxystaurosporine","C054852","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2002,"12015852","7-Hydroxystaurosporine-induced apoptosis in 9L glioma cells provides an effective antigen source for dendritic cells and yields a potent vaccine strategy in an intracranial glioma model.","12015852",40]
["8,9-dihydro-8,9-dihydroxybenzanthracene 10,11-oxide","8,9-dihydro-8,9-dihydroxybenzanthracene 10,11-oxide","C026622","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1980,"22283004","The involvement of a 'bay-region' and a non-'bay-region' diol-epoxide in the metabolic activation of benz[a]anthracene in mouse skin and in hamster embryo cells.","22283004",40]
["8-epi-prostaglandin F2alpha","8-epi-prostaglandin F2alpha","C075750","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2005,"15787871","Inverse association between Chlamydia pneumoniae respiratory tract infection and initiation of asthma or allergic rhinitis in children.","15787871",40]
["9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine","9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine","C050127","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2587248","Mechanism of inhibition of adenovirus DNA replication by the acyclic nucleoside triphosphate analogue (S)-HPMPApp: influence of the adenovirus DNA binding protein.","2587248",40]
["9,10-Dimethyl-1,2-benzanthracene","9,10-Dimethyl-1,2-benzanthracene","D015127","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1991,"1915314","Relationship between DNA adduct formation and unscheduled DNA synthesis (UDS) in cultured mouse epidermal keratinocytes.","1915314",40]
["9,10-Dimethyl-1,2-benzanthracene","9,10-Dimethyl-1,2-benzanthracene","D015127","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1979,"117059","The effects of UVB and 7, 12, dimethylbenz(alpha)anthracene (DMBA) on epidermal melanocytes of the tail in C57BL mice.","117059",40]
["9-benzyl-3-methylene-1,5-di-p-toluenesulfonyl-1,5,9-triazacyclododeane","9-benzyl-3-methylene-1,5-di-p-toluenesulfonyl-1,5,9-triazacyclododeane","C498074","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2007,"17603023","Design and cellular kinetics of dansyl-labeled CADA derivatives with anti-HIV and CD4 receptor down-modulating activity.","17603023",40]
["9-hydroxy-10,12-octadecadienoic acid","9-hydroxy-10,12-octadecadienoic acid","C024347","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10394368","Loss-of-function mutations in PPAR gamma associated with human colon cancer.","10394368",40]
["abietyl alcohol","abietyl alcohol","C026490","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1980,"7408638","[Allergologic studies of intolerance to rosin].","7408638",40]
["ABO Blood-Group System","ABO Blood-Group System","D000017","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1965,"14273763","HUMAN ABO BLOOD GROUP ANTIGENS ON SPERMATOZOA FROM SECRETORS AND NON-SECRETORS.","14273763",40]
["ABO Blood-Group System","ABO Blood-Group System","D000017","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1986,"3538727","[Antigenic similarity of microorganisms to human group-specific blood factors and the immune response of persons with various ABO classifications].","3538727",40]
["ABO Blood-Group System","ABO Blood-Group System","D000017","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2008,"18978296","AB0-incompatible allogeneic hematopoietic stem cell transplantation.","18978296",40]
["ABO Blood-Group System","ABO Blood-Group System","D000017","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26764597","Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.","26764597",40]
["Abscisic Acid","Abscisic Acid","D000040","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19855379","Structural basis of abscisic acid signalling.","19855379",40]
["Abscisic Acid","Abscisic Acid","D000040","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24443499","A role for PacMYBA in ABA-regulated anthocyanin biosynthesis in red-colored sweet cherry cv. Hong Deng (Prunus avium L.).","24443499",40]
["Abscisic Acid","Abscisic Acid","D000040","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28884328","The Glycine soja NAC transcription factor GsNAC019 mediates the regulation of plant alkaline tolerance and ABA sensitivity.","28884328",40]
["acemannan","acemannan","C058414","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1988,"2975271","Enhancement of allo-responsiveness of human lymphocytes by acemannan (Carrisyn).","2975271",40]
["Acetaldehyde","Acetaldehyde","D000079","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"20500519","The alcohol metabolite acetaldehyde and psoriasis: another trigger factor?","20500519",40]
["acetamide","acetamide","C030686","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"22530909","A QSAR analysis of 2-phenoxy-N-substituted acetamide analogues as hypoxia-inducible factor-1(HIF-1) inhibitors: a rational approach to anticancer drug design.","22530909",40]
["Acetaminophen","Acetaminophen","D000082","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2007,"17374012","Urticaria and anaphylaxis to povidone in a paracetamol preparation.","17374012",40]
["Acetaminophen","Acetaminophen","D000082","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,2005,"15859361","Safety of celecoxib in patients with adverse skin reactions to acetaminophen (paracetamol) and nimesulide associated or not with common non-steroidal anti-inflammatory drugs.","15859361",40]
["Acetaminophen","Acetaminophen","D000082","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7281185","Effects of N-acetylcysteine on metabolism, covalent binding, and toxicity of acetaminophen in isolated mouse hepatocytes.","7281185",40]
["acetaminophen glucuronide","acetaminophen glucuronide","C037386","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1986,"3085287","Effects of butylated hydroxyanisole on acetaminophen hepatotoxicity and glucuronidation in vivo.","3085287",40]
["Acetone","Acetone","D000096","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20703875","Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca.","20703875",40]
["Acetrizoic Acid","Acetrizoic Acid","D000100","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1975,"1184321","Failure to induce hypersensitivity reactions to opaque contrast media analogs in guinea pigs.","1184321",40]
["acetyl acetonate","acetyl acetonate","C049529","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1985,"4085238","Contact urticaria and dermatitis from self-adhesive pads.","4085238",40]
["Acetylcholine","Acetylcholine","D000109","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2006,"16512874","Cholinergic control of epidermal cohesion.","16512874",40]
["Acetylcholine","Acetylcholine","D000109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2003,"14622212","Hypocretin-1 causes G protein activation and increases ACh release in rat pons.","14622212",40]
["Acetylcholine","Acetylcholine","D000109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7204380","Interaction of acetylcholine esterase with fluorescent analogs of acetylcholine.","7204380",40]
["Acetylcholine","Acetylcholine","D000109","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22168155","Novel cholinergic peptides SLURP-1 and -2 regulate epithelialization of cutaneous and oral wounds.","22168155",40]
["Acetylgalactosamine","Acetylgalactosamine","D000116","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"560855","Carbohydrate binding specificity of four N-acetyl-D-galactosamine- \"specific\" lectins: Helix pomatia A hemagglutinin, soy bean agglutinin, lima bean lectin, and Dolichos biflorus lectin.","560855",40]
["Acetylglucosamine","Acetylglucosamine","D000117","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"11087713","A novel carbohydrate binding activity of annexin V toward a bisecting N-acetylglucosamine.","11087713",40]
["Acetylglucosamine","Acetylglucosamine","D000117","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15728497","The two major oligomeric forms of human mannan-binding lectin: chemical characterization, carbohydrate-binding properties, and interaction with MBL-associated serine proteases.","15728497",40]
["Acetylglucosamine","Acetylglucosamine","D000117","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7305946","The binding of monosaccharide inhibitors to hen egg-white lysozyme by proton magnetic resonance at 270 MHz and analysis by ring-current calculations.","7305946",40]
["Acetylglucosamine","Acetylglucosamine","D000117","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1996,"8558919","Circulating malignant lymphocytes from Sezary syndrome express high level of glycoproteins carrying beta (1-6)N-acetylglucosamine-branched N-linked oligosaccharides.","8558919",40]
["acrivastine","acrivastine","C043648","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1992,"1355745","An evaluation of the antihistamine activity of acrivastine and its onset in human skin.","1355745",40]
["Acrolein","Acrolein","D000171","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2001,"11329622","Acrolein induces activation of the epidermal growth factor receptor of human keratinocytes for cell death.","11329622",40]
["Acrolein","Acrolein","D000171","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6380709","Metabolism and binding of cyclophosphamide and its metabolite acrolein to rat hepatic microsomal cytochrome P-450.","6380709",40]
["Acrylonitrile","Acrylonitrile","D000181","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26347064","Design, synthesis, and anti-melanogenic effects of (E)-2-benzoyl-3-(substituted phenyl)acrylonitriles.","26347064",40]
["Acticoat","Acticoat","C117408","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20798627","Suprathel-acetic acid matrix versus acticoat and aquacel as an antiseptic dressing: an in vitro study.","20798627",40]
["acyl azide etomidate","acyl azide etomidate","C519839","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17311911","Identification of anesthetic binding sites on human serum albumin using a novel etomidate photolabel.","17311911",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C11203,B11203)","v":"Adamantane"},"Adamantane","D000218","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J11203,K11203)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2014,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q11203,Q11203)","v":"24508127"},"Switching cannabinoid response from CB(2) agonists to FAAH inhibitors.","24508127",40]
["Adapalene","Adapalene","D000068816","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2015,"25960068","Allergic contact dermatitis caused by adapalene.","25960068",40]
["Adenine","Adenine","D000225","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,1998,"9557716","Effectiveness of postinoculation (R)-9-(2-phosphonylmethoxypropyl) adenine treatment for prevention of persistent simian immunodeficiency virus SIVmne infection depends critically on timing of initiation and duration of treatment.","9557716",40]
["Adenine","Adenine","D000225","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2006,"16801436","Activities of alkoxyalkyl esters of cidofovir (CDV), cyclic CDV, and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine against orthopoxviruses in cell monolayers and in organotypic cultures.","16801436",40]
["Adenine","Adenine","D000225","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4512009","Double helical complex formed from a polynucleotide and a complementary monomer.","4512009",40]
["Adenine","Adenine","D000225","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21389257","The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines.","21389257",40]
["A-factor (Streptomyces)","A-factor (Streptomyces)","C025035","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1956957","Molecular mechanisms of the A-factor-dependent control of secondary metabolism in Streptomyces.","1956957",40]
["afimoxifene","afimoxifene","C016601","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23729263","Studying protein-ligand interactions using X-ray crystallography.","23729263",40]
["Aflatoxin B1","Aflatoxin B1","D016604","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"19551989","Biosensor-based screening method for the detection of aflatoxins B1-G1.","19551989",40]
["Agar","Agar","D000362","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1958,"13574927","A simplified modification of the triangular double-diffusion agar precipitin test.","13574927",40]
["Agar","Agar","D000362","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19884780","Purification and characterization of neoagarotetraose from hydrolyzed agar.","19884780",40]
["alantolactone","alantolactone","C004363","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1982,"7165323","Allergic contact dermatitis to methylenelactones. Use of lymphocyte transformation test.","7165323",40]
["Albuterol","Albuterol","D000420","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2005,"15845862","Interleukin-10-secreting \"regulatory\" T cells induced by glucocorticoids and beta2-agonists.","15845862",40]
["Albuterol","Albuterol","D000420","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9184473","The interaction between salmeterol and the beta 2-adrenoceptor protein.","9184473",40]
["Alfentanil","Alfentanil","D015760","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3086065","Alfentanil in anesthesia and analgesia.","3086065",40]
["alginic acid","alginic acid","C008970","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2008,"18462788","The effect of sulfation of alginate hydrogels on the specific binding and controlled release of heparin-binding proteins.","18462788",40]
["aliskiren","aliskiren","C446481","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18957390","Prorenin and the (pro)renin receptor: binding kinetics, signalling and interaction with aliskiren.","18957390",40]
["allergen Can f I","allergen Can f I","C091462","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2015,"26218644","Allergenic Can f 1 and its human homologue Lcn-1 direct dendritic cells to induce divergent immune responses.","26218644",40]
["allicin","allicin","C006452","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19632706","Allicin and disulfiram enhance platelet integrin alphaIIbbeta3-fibrinogen binding.","19632706",40]
["Allopurinol","Allopurinol","D000493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1998,"9665650","Effect of deferoxamine and allopurinol on non-protein-bound iron concentrations in plasma and cortical brain tissue of newborn lambs following hypoxia-ischemia.","9665650",40]
["Allura Red AC Dye","Allura Red AC Dye","C005915","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25306366","Characterisation of interaction between food colourant allura red AC and human serum albumin: multispectroscopic analyses and docking simulations.","25306366",40]
["aloemannan","aloemannan","C120643","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10418327","In vivo metabolism of aloemannan.","10418327",40]
["Alphacopal","Alphacopal","C062046","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1989,"2689081","Contact allergy to Manilla resin. Nomenclature and physico-chemistry of Manilla, kauri, damar and copal resins.","2689081",40]
["alpha-galactosyl epitope","alpha-galactosyl epitope","C076569","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2011,"22162709","Conversion of tumors into autologous vaccines by intratumoral injection of α-Gal glycolipids that induce anti-Gal/α-Gal epitope interaction.","22162709",40]
["alpha-galactosylceramide","alpha-galactosylceramide","C493154","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2007,"17979847","Innate Valpha14(+) natural killer T cells mature dendritic cells, leading to strong adaptive immunity.","17979847",40]
["alpha-galactosylceramide","alpha-galactosylceramide","C493154","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2013,"23935988","Intra-peritoneal hyperthermia combining α-galactosylceramide in the treatment of ovarian cancer.","23935988",40]
["alpha-ketoglutaric acid","alpha-ketoglutaric acid","C029743","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23818625","P(II) signal transduction proteins are ATPases whose activity is regulated by 2-oxoglutarate.","23818625",40]
["alpha-Linolenic Acid","alpha-Linolenic Acid","D017962","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14729912","A plasma membrane protein from Zea mays binds with the herbivore elicitor volicitin.","14729912",40]
["alpha-peroxyachifolid","alpha-peroxyachifolid","C070257","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1815484","[Peroxides as plant constituents. 8. Guaianolide-peroxides from yarrow,Achillea millefolium L., a soluble component causing yarrow dermatitis].","1815484",40]
["alpinetin","alpinetin","C436748","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,2014,"24964870","Immunosuppressive activity of alpinetin on activation and cytokines secretion of murine T lymphocytes.","24964870",40]
["Alprenolol","Alprenolol","D000526","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"913021","Plasma protein binding of basic drugs. II. Importance of alpha 1-acid glycoprotein for interindividual variation.","913021",40]
["aluminum chloride","aluminum chloride","C010845","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1996,"8833470","Evaluation of cutaneous hypersensitivity to aluminum by routine patch testing with A1C1(3).","8833470",40]
["aluminum fluoride","aluminum fluoride","C032311","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9163420","Structure of ADP x AIF4(-)-stabilized nitrogenase complex and its implications for signal transduction.","9163420",40]
["aluminum sulfate","aluminum sulfate","C041524","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2008,"18582945","Molecular differences between the divergent responses of ovalbumin-specific CD4 T cells to alum-precipitated ovalbumin compared to ovalbumin expressed by Salmonella.","18582945",40]
["aluminum sulfate","aluminum sulfate","C041524","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2012,"22474329","A comparative study of stress-mediated immunological functions with the adjuvanticity of alum.","22474329",40]
["Am 580","Am 580","C068073","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"23296452","Reduced retinoid signaling in the skin after systemic retinoid-X receptor ligand treatment in mice with potential relevance for skin disorders.","23296452",40]
["Amifostine","Amifostine","D004999","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2000,"10742082","Systemic inflammatory response syndrome associated with amifostine.","10742082",40]
["Amikacin","Amikacin","D000583","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"17355928","[Pharmacokinetics of amikacin in the subeschar tissue fluid following severe burns].","17355928",40]
["Aminoglutethimide","Aminoglutethimide","D000616","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1987,"2961395","Skin reaction following aminoglutethimide and radiotherapy.","2961395",40]
["aminomethyltrioxsalen","aminomethyltrioxsalen","C018822","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1998,"9490707","Inactivation of leukocytes in platelet concentrates by photochemical treatment with psoralen plus UVA.","9490707",40]
["Aminophylline","Aminophylline","D000628","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1974,"4364952","Alteration of rabbit PCA reaction by drugs known to influence intracellular cyclic AMP.","4364952",40]
["Aminosalicylic Acid","Aminosalicylic Acid","D010131","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21752201","Molecular docking, 3D-QSAR studies, and in silico ADME prediction of p-aminosalicylic acid derivatives as neuraminidase inhibitors.","21752201",40]
["Amiodarone","Amiodarone","D000638","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1985,"3978832","Amiodarone and thyroid hormone action.","3978832",40]
["Amlodipine","Amlodipine","D017311","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"19496159","Stereoselective plasma protein binding of amlodipine.","19496159",40]
["Ammonia","Ammonia","D000641","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22214383","Structure and catalytic mechanism of nicotinate (vitamin B3) degradative enzyme maleamate amidohydrolase from Bordetella bronchiseptica RB50.","22214383",40]
["Ammonium Hydroxide","Ammonium Hydroxide","D064753","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"3365963","Structural determinants of the response of the skin to chemical irritants.","3365963",40]
["Amoxicillin","Amoxicillin","D000658","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2010,"20121757","CD8+ T cells mediate skin allergy to amoxicillin in a mouse model.","20121757",40]
["Amoxicillin","Amoxicillin","D000658","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2013,"23886463","[Mechanism of amoxicillin induced peripheral thrombocytopenia: about one case].","23886463",40]
["Amoxicillin-Potassium Clavulanate Combination","Amoxicillin-Potassium Clavulanate Combination","D019980","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2016,"26860882","[Aminopenicillin-induced exanthematous eruption in a patient with infectious mononucleosis].","26860882",40]
["Amphetamine","Amphetamine","D000661","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4694352","The disposition kinetics of amphetamine in the ruminant animal.","4694352",40]
["Amphotericin B","Amphotericin B","D000666","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"26709977","Topical amphotericin B in ultradeformable liposomes: Formulation, skin penetration study, antifungal and antileishmanial activity in vitro.","26709977",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C14723,B14723)","v":"Ampicillin"},"Ampicillin","D000667","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J14723,K14723)","v":"Drug Eruptions"},"D003875","Drug Eruptions",0,2,2012,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q14723,Q14723)","v":"23163077"},"Two contrasting post-zoster dermatomal phenomena.","23163077",40]
["Ampicillin","Ampicillin","D000667","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1980,"6103375","Amoxicillin and ampicillin: rashes equally likely.","6103375",40]
["amprenavir","amprenavir","C095108","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"16794810","Insights into amprenavir resistance in E35D HIV-1 protease mutation from molecular dynamics and binding free-energy calculations.","16794810",40]
["Amygdalin","Amygdalin","D000678","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23079707","Functional characterization, homology modeling and docking studies of β-glucosidase responsible for bioactivation of cyanogenic hydroxynitrile glucosides from Leucaena leucocephala (subabul).","23079707",40]
["anabaseine","anabaseine","C091713","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20518527","Online fluorescence enhancement assay for the acetylcholine binding protein with parallel mass spectrometric identification.","20518527",40]
["andrographolide","andrographolide","C030419","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"26903706","Andrographolide Sodium Bisulfate Prevents UV-Induced Skin Photoaging through Inhibiting Oxidative Stress and Inflammation.","26903706",40]
["anhydrovitamin A","anhydrovitamin A","C031469","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1993,"8340762","Anhydroretinol: a naturally occurring inhibitor of lymphocyte physiology.","8340762",40]
["Anthralin","Anthralin","D000875","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1992,"1314863","Anthralin decreases keratinocyte TGF-alpha expression and EGF-receptor binding in vitro.","1314863",40]
["Anthralin","Anthralin","D000875","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2002,"12476012","The response of uninvolved skin of patients with psoriasis to single and repeated applications of dithranol cream: an immunohistochemical assessment.","12476012",40]
["anthrarobin","anthrarobin","C032186","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"8565505","Allergic contact dermatitis from anthrarobin.","8565505",40]
["anthrax toxin","anthrax toxin","C030325","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16188881","Effects of spontaneous deamidation on the cytotoxic activity of the Bacillus anthracis protective antigen.","16188881",40]
["anthrax toxin","anthrax toxin","C030325","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21425348","Mechanism of reactant and product dissociation from the anthrax edema factor: a locally enhanced sampling and steered molecular dynamics study.","21425348",40]
["antigen Sm10, Schistosoma","antigen Sm10, Schistosoma","C106491","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1997,"9084036","Characterization of a schistosome T cell-stimulating antigen (Sm10) associated with protective immunity in humans.","9084036",40]
["antigens, CD200","antigens, CD200","C042739","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2016,"27342516","[CD200/CD200R Expression Levels and Its Significance after Allogeneic Hematopoietic Stem Cell Transplantation].","27342516",40]
["Antipyrine","Antipyrine","D000983","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"4045694","Pharmacokinetic evidence for blood flow depression in dose dependent disposition of 4-aminoantipyrine in rabbits.","4045694",40]
["Apamin","Apamin","D001030","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1981,"6165536","[Immunochemical analysis of the neurotoxin apamine and its derivatives].","6165536",40]
["Apigenin","Apigenin","D047310","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,3,2009,"19405952","Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells.","19405952",40]
["Apomorphine","Apomorphine","D001058","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"26645629","Binding Interactions of Dopamine and Apomorphine in D2High and D2Low States of Human Dopamine D2 Receptor Using Computational and Experimental Techniques.","26645629",40]
["aprepitant","aprepitant","C114556","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,2014,"24525842","Topical non-peptide antagonists of sensory neurotransmitters substance P and CGRP do not modify patch test and prick test reactions: a vehicle-controlled, double-blind pilot study.","24525842",40]
["arachidic acid","arachidic acid","C094477","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"26344377","Kojibiose ameliorates arachidic acid-induced metabolic alterations in hyperglycaemic rats.","26344377",40]
["Arachidonic Acid","Arachidonic Acid","D016718","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10551823","The two calcium-binding proteins, S100A8 and S100A9, are involved in the metabolism of arachidonic acid in human neutrophils.","10551823",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C16131,B16131)","v":"Arachidonic Acid"},"Arachidonic Acid","D016718","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J16131,K16131)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2007,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q16131,Q16131)","v":"17804608"},"Inhibition of L-type Ca2+ channel current and negative inotropy induced by arachidonic acid in adult rat ventricular myocytes.","17804608",40]
["Arachidonic Acid","Arachidonic Acid","D016718","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1984,"6420056","Requirement for autologous cancer extracts and lipoxygenation of arachidonic acid for human T-cell responses in leukocyte adherence inhibition and transmembrane potential change assays.","6420056",40]
["Arbutin","Arbutin","D001104","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"18437986","[The effect of aloesin on melanocytes in the pigmented skin equivalent model].","18437986",40]
["arsenic acid","arsenic acid","C025657","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1997,"9219563","Arsenate suppression of human keratinocyte programming.","9219563",40]
["arsenic trioxide","arsenic trioxide","C006632","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25863441","Arsenic trioxide binding to serum proteins.","25863441",40]
["arsenobetaine","arsenobetaine","C038992","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2001,"11156571","Modulation of cell adhesion and viability of cultured murine bone marrow cells by arsenobetaine, a major organic arsenic compound in marine animals.","11156571",40]
["artemisinine","artemisinine","C031327","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15908211","Three-dimensional structure of Plasmodium falciparum Ca2+ -ATPase(PfATP6) and docking of artemisinin derivatives to PfATP6.","15908211",40]
["artesunate","artesunate","C039726","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1994,"8088141","Topical application of artesunate on guinea pig allergic contact dermatitis.","8088141",40]
["ascorbate-2-phosphate","ascorbate-2-phosphate","C011669","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2004,"15378602","Slow-down of age-dependent telomere shortening is executed in human skin keratinocytes by hormesis-like-effects of trace hydrogen peroxide or by anti-oxidative effects of pro-vitamin C in common concurrently with reduction of intracellular oxidative stress.","15378602",40]
["Ascorbic Acid","Ascorbic Acid","D001205","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2016,"26875881","The role of the antioxidant ascorbic acid in the elicitation of contact allergic reactions to p-phenylenediamine.","26875881",40]
["Ascorbic Acid","Ascorbic Acid","D001205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15866766","Ascorbate depletion: a critical step in nickel carcinogenesis?","15866766",40]
["Ascorbic Acid","Ascorbic Acid","D001205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1979,"35158","The mechanism of reduction of single-site redox proteins by ascorbic acid.","35158",40]
["Ascorbic Acid","Ascorbic Acid","D001205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9481873","Thiamine oxidative transformations catalyzed by copper ions and ascorbic acid.","9481873",40]
["Ascorbic Acid","Ascorbic Acid","D001205","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1997,"9284103","The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamin C.","9284103",40]
["Ascorbic Acid","Ascorbic Acid","D001205","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1998,"9853298","Inhibition of apoptosis and virus replication in feline immunodeficiency virus-infected cells by N-acetylcysteine and ascorbic acid.","9853298",40]
["asiaticoside","asiaticoside","C004446","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2015,"25893368","Triterpenes with healing activity: A systematic review.","25893368",40]
["Aspirin","Aspirin","D001241","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2001,"11273998","Aspirin (5 mmol/L) inhibits leukocyte attack and triggered reactive cell proliferation in a 3D human coronary in vitro model.","11273998",40]
["Aspirin","Aspirin","D001241","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2004,"15005690","Histological spectrum of cutaneous reactions to aspirin in chronic idiopathic urticaria.","15005690",40]
["Aspirin","Aspirin","D001241","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"2011121","Acetylsalicylate-human serum albumin interaction as studied by NMR spectroscopy--antigenicity-producing mechanism of acetylsalicylic acid.","2011121",40]
["Aspirin","Aspirin","D001241","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4447065","How aspirin might work: a pharmacokinetic approach.","4447065",40]
["Aspirin","Aspirin","D001241","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2008,"18612428","Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents.","18612428",40]
["astaxanthine","astaxanthine","C005948","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3109483","Resonance Raman study of reconstituted carotenoproteins incorporating astaxanthin and 15,15'-didehydroastaxanthin.","3109483",40]
["astragaloside A","astragaloside A","C052064","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22687479","Topical astragaloside IV-releasing hydrogel improves healing of skin wounds in vivo.","22687479",40]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"12422206","Tackling multiple sclerosis.","12422206",40]
["Atracurium","Atracurium","D001279","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1985,"2408513","Histaminoid responses to atracurium, vecuronium and tubocurarine.","2408513",40]
["Atropine","Atropine","D001285","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20599844","Percutaneous exposure to the nerve agent VX: Efficacy of combined atropine, obidoxime and diazepam treatment.","20599844",40]
["Auranofin","Auranofin","D001310","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1988,"2977188","Immunogenetic and racial determinants of gold toxicity in rheumatoid arthritis.","2977188",40]
["Aurothioglucose","Aurothioglucose","D006051","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,1975,"125528","Effect of aurothioglucose on some allergic and non-allergic skin reactions in animals.","125528",40]
["AWD 12-281","AWD 12-281","C470045","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2002,"12098602","Effects of the phosphodiesterase 4 inhibitors SB 207499 and AWD 12-281 on the inflammatory reaction in a model of allergic dermatitis.","12098602",40]
["Azaperone","Azaperone","D001376","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1839270","Occupational (photo)allergic contact dermatitis from azaperone in a piglet dealer.","1839270",40]
["aziridine","aziridine","C033132","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1994,"8088152","Allergic contact dermatitis from aziridine crosslinker cx100.","8088152",40]
["Azithromycin","Azithromycin","D017963","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2011,"22010986","Drug reaction with eosinophilia and systemic symptoms (DRESS) associated with azithromycin in acute Epstein-Barr virus infection.","22010986",40]
["bafilomycin A","bafilomycin A","C057620","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1988,"3264168","Immunosuppressive effects of the macrolide antibiotic bafilomycin towards lymphocytes and lymphoid cell lines.","3264168",40]
["baicalein","baicalein","C006680","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"27453273","Baicalein induces apoptosis and reduces inflammation in LPS-stimulated keratinocytes by blocking the activation of NF-κB: implications for alleviating oral lichen planus.","27453273",40]
["baicalin","baicalin","C038044","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28158928","Baicalin positively regulates osteoclast function by activating MAPK/Mitf signalling.","28158928",40]
["batridene","batridene","C016259","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6979837","[Effect of the immunosuppressive agent batridene on contact allergic dermatitis induced by 2,4-dinitrochlorobenzene].","6979837",40]
["baysilon","baysilon","C013830","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18627199","Water-in-silicone oil emulsion stabilizing surfactants formed from native albumin and alpha,omega-triethoxysilylpropyl-polydimethylsiloxane.","18627199",40]
["BCG Vaccine","BCG Vaccine","D001500","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2006,"16488518","Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from Mycobacterium tuberculosis increases the survival time of Mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv.","16488518",40]
["BCG Vaccine","BCG Vaccine","D001500","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2011,"21866040","Impaired Bacillus Calmette-Guérin cellular immune response in HIV-exposed, uninfected infants.","21866040",40]
["BCG Vaccine","BCG Vaccine","D001500","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2014,"24690183","Polyclonal activation of naïve T cells by urease deficient-recombinant BCG that produced protein complex composed of heat shock protein 70, CysO and major membrane protein-II.","24690183",40]
["BCG Vaccine","BCG Vaccine","D001500","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2009,"19064635","Immunogenicity and protective efficacy of prime-boost regimens with recombinant (delta)ureC hly+ Mycobacterium bovis BCG and modified vaccinia virus ankara expressing M. tuberculosis antigen 85A against murine tuberculosis.","19064635",40]
["BCG Vaccine","BCG Vaccine","D001500","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2015,"26108288","Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of Macaques.","26108288",40]
["BCG Vaccine","BCG Vaccine","D001500","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1998,"9659324","Exacerbation of atopic dermatitis after bacillus Calmette-Guérin vaccination.","9659324",40]
["BCG Vaccine","BCG Vaccine","D001500","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1966,"5943373","[Evolution of BCG post-vaccination allergy and related defense mechanisms].","5943373",40]
["BCG Vaccine","BCG Vaccine","D001500","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,2017,"28660649","Neonatal BCG has no effect on allergic sensitization and suspected food allergy until 13 months.","28660649",40]
["BCG Vaccine","BCG Vaccine","D001500","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2009,"19550341","Effective anti-tumor responses induced by recombinant bacillus Calmette-Guérin vaccines based on different tandem repeats of MUC1 and GM-CSF.","19550341",40]
["BCG Vaccine","BCG Vaccine","D001500","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2467445","Analysis of Mycobacterium tuberculosis genoma and production of a recombinant protein containing specific B and T cell antigenic determinants--new approaches to second generation antituberculosis vaccines.","2467445",40]
["BCG Vaccine","BCG Vaccine","D001500","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1980,"6965664","Difference in antigen-presenting ability of macrophages between high- and low-responder mice in delayed-type hypersensitivity to Mycobacterium bovis BCG.","6965664",40]
["BCG Vaccine","BCG Vaccine","D001500","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1993,"8417205","Antitumor effects of bacillus Calmette-Guerin in a syngeneic rat bladder tumor model system, RBT323.","8417205",40]
["Benactyzine","Benactyzine","D001535","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4450999","Proceedings: Some factors influencing the effects of benactyzine.","4450999",40]
["Bendroflumethiazide","Bendroflumethiazide","D001539","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"4096738","Skin blister fluid--an access to the peripheral compartment. Implications of a study on the behaviour of bendroflumethiazide in rats.","4096738",40]
["Bentonite","Bentonite","D001546","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,1,2001,"11685665","A skin moisturizing cream containing Quaternium-18-Bentonite effectively improves chronic hand dermatitis.","11685665",40]
["Benzene","Benzene","D001554","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18069094","Substituted benzylaminoalkylindoles with preference for the sigma2 binding site.","18069094",40]
["Benzene","Benzene","D001554","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6982049","The effect of organic solvents on the lymphocyte rosette tests and the immunoglobulin level.","6982049",40]
["benzeneboronic acid","benzeneboronic acid","C010686","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8102883","Immobilized phenylboronic acids for the selective extraction of beta-blocking drugs from aqueous solution and plasma.","8102883",40]
["Benzo(a)pyrene","Benzo(a)pyrene","D001564","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2012,"22951985","Activation of the aryl hydrocarbon receptor sensitises human keratinocytes for CD95L- and TRAIL-induced apoptosis.","22951985",40]
["Benzo(a)pyrene","Benzo(a)pyrene","D001564","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27262192","Interaction of Nucleotide Excision Repair Protein XPC-RAD23B with DNA Containing Benzo[a]pyrene-Derived Adduct and Apurinic/Apyrimidinic Site within a Cluster.","27262192",40]
["Benzo(a)pyrene","Benzo(a)pyrene","D001564","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1995,"7859347","Inhibition of tumor promotion in benzo[a]pyrene-initiated CD-1 mouse skin by crocetin.","7859347",40]
["benzo(b)thiophene-2-carboxylic acid","benzo(b)thiophene-2-carboxylic acid","C026163","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1984,"6331614","Benzo(B)thiophene-2-carboxylic acid: calcium uptake and cyclic AMP production in isolated bone cells.","6331614",40]
["benzonidazole","benzonidazole","C009999","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2002,"12435678","Benznidazole treatment following acute Trypanosoma cruzi infection triggers CD8+ T-cell expansion and promotes resistance to reinfection.","12435678",40]
["benzonitrile","benzonitrile","C014356","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24948704","A novel benzonitrile analogue inhibits rhinovirus replication.","24948704",40]
["benzothiazole","benzothiazole","C005465","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20204681","A spectroscopic study of 2-[4'-(dimethylamino)phenyl]-benzothiazole binding to insulin amyloid fibrils.","20204681",40]
["Benzoyl Peroxide","Benzoyl Peroxide","D001585","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1986,"3741801","Effect of repeated skin administration on in vivo percutaneous absorption of drugs.","3741801",40]
["Benztropine","Benztropine","D001590","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22895898","Novel C-1 substituted cocaine analogs unlike cocaine or benztropine.","22895898",40]
["Bepridil","Bepridil","D015764","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9525919","Identification of binding sites for bepridil and trifluoperazine on cardiac troponin C.","9525919",40]
["Berberine","Berberine","D001599","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22765939","Interaction mechanism between berberine and the enzyme lysozyme.","22765939",40]
["bermoprofen","bermoprofen","C040006","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,1988,"3265405","[Inhibitory effect of AD-1590, a non-steroidal anti-inflammatory drug, on allergic inflammation in mice and rats].","3265405",40]
["beta Carotene","beta Carotene","D019207","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27379378","Reducing the Harmful Effects of Infrared Radiation on the Skin Using Bicosomes Incorporating β-Carotene.","27379378",40]
["beta,beta-dimethylacryloyl alkannin","beta,beta-dimethylacryloyl alkannin","C000617126","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27697724","Suppressive effect of β,β-dimethylacryloyl alkannin on activated dendritic cells in psoriasis by the TLR7/8 pathway.","27697724",40]
["betadex","betadex","C031215","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16856195","Supramolecular control of oligosaccharide-protein interactions: switchable and tunable ligands for concanavalin A based on beta-cyclodextrin.","16856195",40]
["beta-elemene","beta-elemene","C445979","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16041842","The pharmacokinetics of a novel anti-tumor agent, beta-elemene, in Sprague-Dawley rats.","16041842",40]
["beta-hydroxyisovaleric acid","beta-hydroxyisovaleric acid","C004961","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25143371","The relative bioavailability of the calcium salt of β-hydroxy-β-methylbutyrate is greater than that of the free fatty acid form in rats.","25143371",40]
["Betamethasone","Betamethasone","D001623","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2004,"15059096","Topical corticosteroid allergy in an urban Australian centre.","15059096",40]
["Betamethasone","Betamethasone","D001623","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1986,"3709148","Contact sensitivity to clobetasol propionate.","3709148",40]
["Betamethasone","Betamethasone","D001623","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27480519","Effect of betamethasone on patch test reactivity in patients with parthenium dermatitis.","27480519",40]
["Betamethasone","Betamethasone","D001623","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"7605335","Structure-activity relationships in glucocorticoid-induced apoptosis in T lymphocytes.","7605335",40]
["beta-penta-O-galloyl-glucose","beta-penta-O-galloyl-glucose","C013185","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"22260360","Epigallocatechin-3-gallate and penta-O-galloyl-β-D-glucose inhibit protein phosphatase-1.","22260360",40]
["betulinic acid","betulinic acid","C002070","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2005,"16077934","Transient activation of EGFR/AKT cell survival pathway and expression of survivin contribute to reduced sensitivity of human melanoma cells to betulinic acid.","16077934",40]
["BI 2536","BI 2536","C518477","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"18005335","Selectivity-determining residues in Plk1.","18005335",40]
["Bilirubin","Bilirubin","D001663","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2016,"27578921","Conjugated Bilirubin Differentially Regulates CD4+ T Effector Cells and T Regulatory Cell Function through Outside-In and Inside-Out Mechanisms: The Effects of HAV Cell Surface Receptor and Intracellular Signaling.","27578921",40]
["Bilirubin","Bilirubin","D001663","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1975,"1185408","The lack of effect of phototherapy on serum bilirubin-binding capacity in newborn infants.","1185408",40]
["Bilirubin","Bilirubin","D001663","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2779527","Ceftriaxone binding to human serum albumin: competition with bilirubin.","2779527",40]
["Bilirubin","Bilirubin","D001663","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3822673","Binding effect of albumin on uptake of bilirubin by brain.","3822673",40]
["Bilirubin","Bilirubin","D001663","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4436437","Competitive binding of bilirubin and drugs to human serum albumin studied by enzymatic oxidation.","4436437",40]
["Bilirubin","Bilirubin","D001663","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1969,"5367658","[Recent acquisitions concerning hepatic chromosecretion].","5367658",40]
["Bilirubin","Bilirubin","D001663","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1967,"6070129","The use and possible diagnostic significance of sephadex gel filtration of serum from icteric newborn.","6070129",40]
["Bilirubin","Bilirubin","D001663","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"7438433","Analysis of fluorescence quenching data by the method of Levine.","7438433",40]
["Bilirubin","Bilirubin","D001663","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8820620","The influence of clinical status on total bilirubin binding capacity in newborn infants.","8820620",40]
["bilirubin glucuronate","bilirubin glucuronate","C016266","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26632182","Estimating the Differences of UGT1A1 Activity in Recombinant UGT1A1 Enzyme, Human Liver Microsomes and Rat Liver Microsome Incubation Systems in Vitro.","26632182",40]
["Biopterin","Biopterin","D001708","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2005,"16293777","A novel mechanism in control of human pigmentation by {beta}-melanocyte-stimulating hormone and 7-tetrahydrobiopterin.","16293777",40]
["Biopterin","Biopterin","D001708","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17658743","Interaction energies between tetrahydrobiopterin analogues and aromatic residues in tyrosine hydroxylase and phenylalanine hydroxylase.","17658743",40]
["Biotin","Biotin","D001710","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,2007,"17425345","Steric crowding effects on target detection in an affinity biosensor.","17425345",40]
["Biotin","Biotin","D001710","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10796986","Extremely high thermal stability of streptavidin and avidin upon biotin binding.","10796986",40]
["Biotin","Biotin","D001710","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14763851","Affinity purification of lipid vesicles.","14763851",40]
["Biotin","Biotin","D001710","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20142036","The switch regulating transcription of the Escherichia coli biotin operon does not require extensive protein-protein interactions.","20142036",40]
["Biotin","Biotin","D001710","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"22038806","Aromatic side-chain cluster of biotin binding site of avidin allows circular dichroism spectroscopic investigation of its ligand binding properties.","22038806",40]
["Biotin","Biotin","D001710","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"4052026","Detection of the low-density-lipoprotein receptor with biotin-low-density lipoprotein. A rapid new method for ligand blotting.","4052026",40]
["Biotin","Biotin","D001710","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7028859","Suppression of endogenous avidin-binding activity in tissues and its relevance to biotin-avidin detection systems.","7028859",40]
["Biotin","Biotin","D001710","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9258456","Biotin-pyrene conjugates with poly(ethylene glycol) spacers are convenient fluorescent probes for avidin and streptavidin.","9258456",40]
["bis(aminopropyl)laurylamine","bis(aminopropyl)laurylamine","C109057","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2010,"20946459","Occupational allergic contact dermatitis caused by N-(3-aminopropyl)-N-dodecylpropane-1,3-diamine in a surface disinfectant.","20946459",40]
["bisabolangelone","bisabolangelone","C455067","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2013,"23727177","Bisabolangelone inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.","23727177",40]
["bisphenol A","bisphenol A","C006780","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20510433","Investigation of the interaction between endocrine disruptor bisphenol A and human serum albumin.","20510433",40]
["bisphenol A","bisphenol A","C006780","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28645579","Anti-androgenic mechanisms of Bisphenol A involve androgen receptor signaling pathway.","28645579",40]
["blood dendritic cell antigen 3, human","blood dendritic cell antigen 3, human","C516094","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2006,"17000725","The frequency of BDCA3-positive dendritic cells is increased in the peripheral circulation of Kenyan children with severe malaria.","17000725",40]
["Blood Glucose","Blood Glucose","D001786","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11872677","Albumin binding of acylated insulin (NN304) does not deter action to stimulate glucose uptake.","11872677",40]
["Blood Glucose","Blood Glucose","D001786","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26833058","Polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9).","26833058",40]
["BO 2727","BO 2727","C085890","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9099223","Affinities of BO-2727 for bacterial penicillin-binding proteins and morphological change of gram-negative rods.","9099223",40]
["boranophosphate","boranophosphate","C510710","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2014,"25150148","Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes.","25150148",40]
["Bortezomib","Bortezomib","D000069286","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2009,"20524309","Bortezomib as therapy for mixed humoral and cellular rejection: should it be first line?","20524309",40]
["botrocetin","botrocetin","C030961","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15665869","The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation.","15665869",40]
["brazilin","brazilin","C044362","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23605640","Interaction of plant pigment brazilin with synthetic and natural DNA: spectroscopic and in silico perspective.","23605640",40]
["Bromcresol Purple","Bromcresol Purple","D001962","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3214125","Serum albumin by dye-binding: bromocresol green or bromocresol purple? The case for conservatism.","3214125",40]
["Bromocriptine","Bromocriptine","D001971","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14630029","Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopy.","14630029",40]
["brotizolam","brotizolam","C020960","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6661377","Pharmacokinetics of oral brotizolam in patients with liver cirrhosis.","6661377",40]
["Brucella Vaccine","Brucella Vaccine","D002004","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1974,"4280294","[Immunomorphological changes in the vessels induced by vaccination against brucellosis].","4280294",40]
["bryostatin 1","bryostatin 1","C046785","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1988,"3263149","Regulation of hematopoiesis-IV: The role of interleukin-3 and bryostatin 1 in the growth of erythropoietic progenitors from normal and anemic W/Wv mice.","3263149",40]
["Budesonide","Budesonide","D019819","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1993,"8508649","Contact allergy to topical budesonide in nasal spray.","8508649",40]
["Budesonide","Budesonide","D019819","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1992,"1445051","Spongiotic (eczematous-type) dermatitis after inhaled budesonide.","1445051",40]
["bufuralol","bufuralol","C010831","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14977863","Impact of incubation conditions on bufuralol human clearance predictions: enzyme lability and nonspecific binding.","14977863",40]
["Bupivacaine","Bupivacaine","D002045","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1986,"3954004","A mistaken case of hypersensitivity to a local anaesthetic.","3954004",40]
["Bupropion","Bupropion","D016642","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,1,2001,"11480688","Bupropion-induced hypersensitivity reactions.","11480688",40]
["Busulfan","Busulfan","D002066","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2006,"17269453","Induction of tolerance across fully mismatched barriers by a nonmyeloablative treatment excluding antibodies or irradiation use.","17269453",40]
["Busulfan","Busulfan","D002066","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1989,"2663795","Late tissue-specific toxicity of total body irradiation and busulfan in a murine bone marrow transplant model.","2663795",40]
["Butylated Hydroxytoluene","Butylated Hydroxytoluene","D002084","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1984,"6498327","[Effect of dibunol liniment on posttraumatic skin regeneration in mice].","6498327",40]
["Butyric Acid","Butyric Acid","D020148","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1993,"8500547","Modulation of SPARC expression during butyrate-induced terminal differentiation of cultured human keratinocytes: regulation via a TGF-beta-dependent pathway.","8500547",40]
["cabozantinib","cabozantinib","C558660","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"25427282","Cutaneous adverse effects associated with the tyrosine-kinase inhibitor cabozantinib.","25427282",40]
["Cadmium Chloride","Cadmium Chloride","D019256","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6083804","Cadmium binding to human alpha 2-macroglobulin.","6083804",40]
["caffeic acid","caffeic acid","C040048","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2014,"25329614","Caffeic acid reduces the viability and migration rate of oral carcinoma cells (SCC-25) exposed to low concentrations of ethanol.","25329614",40]
["Caffeine","Caffeine","D002110","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3225766","Caffeine as a potential risk factor for theophylline neurotoxicity.","3225766",40]
["Caffeine","Caffeine","D002110","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1972,"5031131","[Inhibition of dermographism in human skin after topical application of caffeine].","5031131",40]
["Calcifediol","Calcifediol","D002112","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14657394","A pathway for the metabolism of vitamin D3: unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1).","14657394",40]
["Calcimycin","Calcimycin","D000001","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1992,"1491510","Characterization of the triphenyltin-induced increase in intracellular Ca2+ of mouse thymocytes: comparison with the action of A23187.","1491510",40]
["Calcimycin","Calcimycin","D000001","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1984,"6433775","Ionophore A23-187 induces responses to TCGF in mouse lymphocytes.","6433775",40]
["calcipotriene","calcipotriene","C055085","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10026395","Decrease in enkephalin levels in psoriatic lesions after calcipotriol and mometasone furoate treatment.","10026395",40]
["calcipotriene","calcipotriene","C055085","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9602871","The calcipotriol dose-irritation relationship: 48 hour occlusive testing in healthy volunteers using Finn Chambers.","9602871",40]
["Calcitriol","Calcitriol","D002117","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2007,"17182549","1,25-Dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells.","17182549",40]
["Calcitriol","Calcitriol","D002117","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1999,"10048649","Contact allergy to calcipotriol does exist. Report of an unequivocal case and review of the literature.","10048649",40]
["Calcitriol","Calcitriol","D002117","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1999,"10377179","Mitogen-activated protein kinase inhibits 1,25-dihydroxyvitamin D3-dependent signal transduction by phosphorylating human retinoid X receptor alpha.","10377179",40]
["Calcitriol","Calcitriol","D002117","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2010,"20153426","Conversion of vitamin D3 to hormonally active 1alpha,25-dihydroxyvitamin D3 in cultured keratinocytes: relevance to cell growth and differentiation.","20153426",40]
["Calcitriol","Calcitriol","D002117","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1995,"7598535","Distribution of 1,25-dihydroxyvitamin D3[22-oxa] in vivo receptor binding in adult and developing skin.","7598535",40]
["Calcitriol","Calcitriol","D002117","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12796488","2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts.","12796488",40]
["Calcitriol","Calcitriol","D002117","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"19815065","H2O2-dependent translocation of TCTP into the nucleus enables its interaction with VDR in human keratinocytes: TCTP as a further module in calcitriol signalling.","19815065",40]
["Calcitriol","Calcitriol","D002117","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28636886","SIRT1 enzymatically potentiates 1,25-dihydroxyvitamin D3 signaling via vitamin D receptor deacetylation.","28636886",40]
["Calcitriol","Calcitriol","D002117","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"20969563","A randomized, double-blind, negatively controlled pilot study to determine whether the use of emollients or calcipotriol alters the sensitivity of the skin to ultraviolet radiation during phototherapy with narrowband ultraviolet B.","20969563",40]
["Calcitriol","Calcitriol","D002117","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"11014983","Constant, but not pulsed calcitriol suppresses hemodialysis patients' antigen-induced lymphocyte proliferation.","11014983",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C26179,B26179)","v":"Calcitriol"},"Calcitriol","D002117","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J26179,K26179)","v":"T-Lymphocytes"},"D013601","T-Lymphocytes",1,3,1996,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q26179,Q26179)","v":"8983428"},"[Mechanism of immunomodulating effect of vitamin D: possible involvement of lipid peroxidation system].","8983428",40]
["Calcium Chloride","Calcium Chloride","D002122","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1987,"3610796","Calcinosis cutis secondary to percutaneous penetration of calcium chloride in dogs.","3610796",40]
["calcium phosphate","calcium phosphate","C020243","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28261732","Mineral binding peptides with enhanced binding stability in serum.","28261732",40]
["Calcium, Dietary","Calcium, Dietary","D002136","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2015,"26097536","Inhibition of 4-nitroquinoline-1-oxide-induced oral carcinogenesis by dietary calcium.","26097536",40]
["calix(4)arene","calix(4)arene","C121325","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20023949","Densely packed Gd(III)-chelates with fast water exchange on a calix[4]arene scaffold: a potential MRI contrast agent.","20023949",40]
["Camptothecin","Camptothecin","D002166","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2016,"27793873","Unusual case of hyperpigmentation secondary to irinotecan.","27793873",40]
["Camptothecin","Camptothecin","D002166","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25060396","Contribution of transcription factor, SP1, to the promotion of HB-EGF expression in defense mechanism against the treatment of irinotecan in ovarian clear cell carcinoma.","25060396",40]
["Canola Oil","Canola Oil","D000074262","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24393360","BnWRI1 coordinates fatty acid biosynthesis and photosynthesis pathways during oil accumulation in rapeseed.","24393360",40]
["Canthaxanthin","Canthaxanthin","D016644","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1993,"8129287","Cancer prevention by carotenoids. Mechanistic studies in cultured cells.","8129287",40]
["Capsaicin","Capsaicin","D002211","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2012,"22579786","Tumor macrophages as a target for Capsaicin mediated immunotherapy.","22579786",40]
["Capsaicin","Capsaicin","D002211","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1992,"1630631","The partial inhibition of inflammatory responses induced by capsaicin using the Fab fragment of a selective calcitonin gene-related peptide antiserum in rabbit skin.","1630631",40]
["Capsaicin","Capsaicin","D002211","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"24819823","Gender differences in itch and pain-related sensations provoked by histamine, cowhage and capsaicin.","24819823",40]
["carazolol","carazolol","C014382","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22748765","Ligand-specific interactions modulate kinetic, energetic, and mechanical properties of the human β2 adrenergic receptor.","22748765",40]
["Carbamazepine","Carbamazepine","D002220","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1999,"10709136","Carbamazepine hypersensitivity syndrome.","10709136",40]
["Carbamazepine","Carbamazepine","D002220","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1981,"6452860","Skin reactions to carbamazepine.","6452860",40]
["Carbamazepine","Carbamazepine","D002220","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18096676","CYP3A4-Mediated carbamazepine (CBZ) metabolism: formation of a covalent CBZ-CYP3A4 adduct and alteration of the enzyme kinetic profile.","18096676",40]
["Carbamazepine","Carbamazepine","D002220","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6650125","Pharmacokinetics of 10-OH-carbazepine, the main metabolite of the antiepileptic oxcarbazepine, from serum and saliva concentrations.","6650125",40]
["Carbaryl","Carbaryl","D012721","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1992,"1360392","The nature of Cl- secretion, induced by carbaryl, across the isolated skin of Rana esculenta.","1360392",40]
["Carbenoxolone","Carbenoxolone","D002229","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"606633","Changes in the plasma clearance and protein binding of carbenoxolone with age, and their possible relationship with adverse drug effects.","606633",40]
["Carbon Dioxide","Carbon Dioxide","D002245","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1962,"14037882","Separation of antigens by immunological specificity. 2. Release of antigen and antibody from their complexes by aqueous carbon dioxide.","14037882",40]
["Carbon Dioxide","Carbon Dioxide","D002245","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1966,"6003322","[Effect of carbon dioxide on the organism].","6003322",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C27587,B27587)","v":"Carbon Monoxide"},"Carbon Monoxide","D002248","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J27587,K27587)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2001,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q27587,Q27587)","v":"11264014"},"Carbon monoxide complex of cytochrome b(5) at acidic pH.","11264014",40]
["Carbon Monoxide","Carbon Monoxide","D002248","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20353168","Probing soluble guanylate cyclase activation by CO and YC-1 using resonance Raman spectroscopy.","20353168",40]
["Carbon Monoxide","Carbon Monoxide","D002248","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23661270","Effects of local protein environment on the binding of diatomic molecules to heme in myoglobins. DFT and dispersion-corrected DFT studies.","23661270",40]
["Carbon Monoxide","Carbon Monoxide","D002248","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4364769","Heme-heme interaction in cytochrome c oxidase: the cooperativity of the hemes of cytochrome c oxidase as evidenced in the reaction with CO.","4364769",40]
["Carbon Monoxide","Carbon Monoxide","D002248","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"6474","Dissociation of CO from carboxyhemoglobin.","6474",40]
["Carbon Monoxide","Carbon Monoxide","D002248","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"857909","A carbon monoxide derivative of ruthenium (II) myoglobin probe of heme protein conformation.","857909",40]
["Carbon Tetrachloride","Carbon Tetrachloride","D002251","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"6287730","[Significance of biochemical indices of liver fibrosis].","6287730",40]
["Carboplatin","Carboplatin","D016190","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2009,"19307994","The Immune adjuvant properties of front-line carboplatin-paclitaxel: a randomized phase 2 study of alternative schedules of intravenous oregovomab chemoimmunotherapy in advanced ovarian cancer.","19307994",40]
["carboxymethyl dextran","carboxymethyl dextran","C014392","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16620750","Covalent immobilization of histidine-tagged proteins for surface plasmon resonance.","16620750",40]
["Carboxymethylcellulose Sodium","Carboxymethylcellulose Sodium","D002266","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2011,"21480918","Cutaneous adverse drug reactions caused by delayed sensitization to carboxymethylcellulose.","21480918",40]
["carcinoma-associated antigen 17-1A","carcinoma-associated antigen 17-1A","C050928","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1997,"9435872","Construction and biological activity of a recombinant bispecific single-chain antibody designed for therapy of minimal residual colorectal cancer.","9435872",40]
["carprofen","carprofen","C007005","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12712611","In vitro stereoselective covalent binding of carprofen glucuronides to human serum albumin: characterization of the mechanism.","12712611",40]
["Carrageenan","Carrageenan","D002351","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27030165","Effects of conformational ordering on protein/polyelectrolyte electrostatic complexation: ionic binding and chain stiffening.","27030165",40]
["castanospermine","castanospermine","C037806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9642271","Inhibition of glucose trimming with castanospermine reduces calnexin association and promotes proteasome degradation of the alpha-subunit of the nicotinic acetylcholine receptor.","9642271",40]
["catalpol","catalpol","C078040","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27301615","Catalpol stimulates VEGF production via the JAK2/STAT3 pathway to improve angiogenesis in rats' stroke model.","27301615",40]
["Catechin","Catechin","D002392","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1997,"9261215","[Effect of tea extracts, catechin and caffeine against type-I allergic reaction].","9261215",40]
["Catechin","Catechin","D002392","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21228463","Human serum albumin as an antioxidant in the oxidation of (-)-epigallocatechin gallate: participation of reversible covalent binding for interaction and stabilization.","21228463",40]
["Catechin","Catechin","D002392","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2014,"24759182","Epigallocatechin gallate suppresses LPS endocytosis and nitric oxide production by reducing Rab5-caveolin-1 interaction.","24759182",40]
["Catechin","Catechin","D002392","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2009,"19735514","Protective effect of epigallocatechin gallate on the immune function of dendritic cells after ultraviolet B irradiation.","19735514",40]
["catharanthine","catharanthine","C017836","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25588192","Theoretical insight into the structural mechanism for the binding of vinblastine with tubulin.","25588192",40]
["CC 1065","CC 1065","C018782","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1996,"8781375","End points for biomonitoring: assay sensitivity/selectivity.","8781375",40]
["CD1a antigen","CD1a antigen","C419393","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2014,"25001859","Elevated postinjury thrombospondin 1-CD47 triggering aids differentiation of patients' defective inflammatory CD1a+dendritic cells.","25001859",40]
["CD1a antigen","CD1a antigen","C419393","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2005,"15723809","Molecular mechanism of lipopeptide presentation by CD1a.","15723809",40]
["CD223 antigen","CD223 antigen","C076113","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2016,"26696540","Expression of PD-1/LAG-3 and cytokine production by CD4(+) T cells during infection with Plasmodium parasites.","26696540",40]
["CD223 antigen","CD223 antigen","C076113","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2007,"17785860","A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells.","17785860",40]
["CD226 antigen","CD226 antigen","C108133","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2015,"26359290","Multiple sclerosis associated genetic variants of CD226 impair regulatory T cell function.","26359290",40]
["CD226 antigen","CD226 antigen","C108133","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2005,"15752754","Identification and characterization of murine DNAM-1 (CD226) and its poliovirus receptor family ligands.","15752754",40]
["CD3 antigen, gamma chain","CD3 antigen, gamma chain","C452842","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21764047","CD3γ-independent pathways in TCR-mediated signaling in mature T and iNKT lymphocytes.","21764047",40]
["CD3 Complex","CD3 Complex","D017252","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1991,"1834468","A humanized monovalent CD3 antibody which can activate homologous complement.","1834468",40]
["CD3 Complex","CD3 Complex","D017252","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,1991,"1827479","Human bronchial epithelial cells modulate CD3 and mitogen-induced DNA synthesis in T cells but function poorly as antigen-presenting cells compared to pulmonary macrophages.","1827479",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C29699,B29699)","v":"CD3 Complex"},"CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J29699,K29699)","v":"CD4-Positive T-Lymphocytes"},"D015496","CD4-Positive T-Lymphocytes",1,1,2001,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q29699,Q29699)","v":"11714771"},"Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3 zeta signaling receptor molecule.","11714771",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2005,"16018273","[Comparative investigation of the hematologic and immunologic effects of splenectomy and spleen autotransplantation in mice].","16018273",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2009,"19172487","Functional characterization of N297A, a murine surrogate for low-Fc binding anti-human CD3 antibodies.","19172487",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1995,"7783685","CD3+/TCR-alpha beta- cells are important in protecting spinal cord tissues against Theiler's virus strain GD VII infection.","7783685",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1998,"9767441","A comparison of two techniques for the molecular tracking of specific T-cell responses; CD4+ human T-cell clones persist in a stable hierarchy but at a lower frequency than clones in the CD8+ population.","9767441",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2012,"22077498","Increased natural killer cells and decreased CD3(+)CD8(+)CD62L(+) T cells in CML patients who sustained complete molecular remission after discontinuation of imatinib.","22077498",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,1995,"7622182","The outer surface lipoprotein A of Borrelia burgdorferi provides direct and indirect augmenting/co-stimulatory signals for the activation of CD4+ and CD8+ T cells.","7622182",40]
["CD3 Complex","CD3 Complex","D017252","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2008,"18438416","CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells.","18438416",40]
["CD3 Complex","CD3 Complex","D017252","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2017,"28465009","Crk adaptor proteins regulate CD3ζ chain phosphorylation and TCR/CD3 down-modulation in activated T cells.","28465009",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1999,"10384095","The CD3 epsilon subunit of the TCR contains endocytosis signals.","10384095",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2001,"11298321","Down-modulation of TCR/CD3 surface complexes after HIV-1 infection is associated with differential expression of the viral regulatory genes.","11298321",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2002,"11854357","Characterization of T cell differentiation in the murine gut.","11854357",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2003,"12679562","Bulk cultures of canine peripheral blood lymphocytes with solid phase anti-CD3 antibody and recombinant interleukin-2 for use in immunotherapy.","12679562",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2003,"14659899","Use of anti-CD3/CD28 mAb coupled magnetic beads permitting subsequent phenotypic analysis of activated human T cells by indirect immunofluorescence.","14659899",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1992,"1534027","Effects of anti-CD3 monoclonal antibody on engraftment of T-cell-depleted bone marrow allografts in mice: host T-cell suppression, growth factors, and space.","1534027",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1990,"1688586","Activation of human T lymphocytes via the CD2 antigen results in tyrosine phosphorylation of T cell antigen receptor zeta-chains.","1688586",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1991,"1714644","Anti-CD3 monoclonal antibody therapy. An approach toward optimization by in vitro analysis of new anti-CD3 antibodies.","1714644",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2007,"17997796","Differential expression of T-cell CD3-zeta chains in patients with cervical dysplasia before and after treatment.","17997796",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1991,"1849799","Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction.","1849799",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1990,"1970592","The expanded populations of CD4-CD8- T cell receptor alpha/beta+ T cells associated with the lpr and gld mutations are CD2-.","1970592",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1990,"2143171","Generation of alloreactive cytolytic T lymphocytes by immobilized anti-CD3 monoclonal antibodies. Analysis of requirements for human cytolytic T-lymphocyte differentiation.","2143171",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C31107,B31107)","v":"CD3 Complex"},"CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J31107,K31107)","v":"T-Lymphocytes"},"D013601","T-Lymphocytes",1,1,1990,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q31107,Q31107)","v":"2152856"},"FcR-mediated crosslinking of Ta1 (CDw26) induces human T lymphocyte activation.","2152856",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2470516","Murine anti-CD3 monoclonal antibody induces potent cytolytic activity in both T and NK cell populations.","2470516",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2523173","Usefulness of CD3 or CD6 anti-T monoclonal antibodies in the treatment of acute corneal graft rejection.","2523173",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"25514620","Discriminant score for celiac disease based on immunohistochemical analysis of duodenal biopsies.","25514620",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2017,"28433528","Evolutionary history of the T cell receptor complex as revealed by small-spotted catshark (Scyliorhinus canicula).","28433528",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1986,"2944201","The structure and function of the T3-Ti molecular complex on human T lymphocytes.","2944201",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1995,"7636241","Identification of heavy chain residues in a humanized anti-CD3 antibody important for efficient antigen binding and T cell activation.","7636241",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1995,"7879076","Pathogenesis and therapy of cytomegalovirus (CMV)-associated lung disease following anti-CD3 monoclonal antibody treatment in mice with persistent murine CMV in the salivary glands.","7879076",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1993,"8117800","Immunohistochemical analysis of tissue distribution of B and T cells in germfree and conventional chickens.","8117800",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1997,"9023553","Production and characterization of a new monoclonal antibody effective in recognizing the CD3 T-cell associated antigen in formalin-fixed embedded tissue.","9023553",40]
["CD3 Complex","CD3 Complex","D017252","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1997,"9363914","FK506 enhances IL-13 production by T cells activated through CD3/CD28.","9363914",40]
["CD6 antigen","CD6 antigen","C062279","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2014,"24662291","Syntenin-1 and ezrin proteins link activated leukocyte cell adhesion molecule to the actin cytoskeleton.","24662291",40]
["CD6 antigen","CD6 antigen","C062279","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2013,"23568178","CD6 as a therapeutic target in autoimmune diseases: successes and challenges.","23568178",40]
["CD8 antigen, alpha chain","CD8 antigen, alpha chain","C409469","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2010,"19950178","An active CD8alpha/pMHCI interaction is required for CD8 single positive thymocyte differentiation.","19950178",40]
["CD8 antigen, alpha chain","CD8 antigen, alpha chain","C409469","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2014,"24104458","Characterizing CEACAM5 interaction with CD8α and CD1d in intestinal homeostasis.","24104458",40]
["CD8 antigen, alpha chain","CD8 antigen, alpha chain","C409469","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2016,"27543048","Medullary thymic epithelial cells and CD8α+ dendritic cells coordinately regulate central tolerance but CD8α+ cells are dispensable for thymic regulatory T cell production.","27543048",40]
["CD8alpha antigen","CD8alpha antigen","C431698","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2002,"11751957","Immature and mature CD8alpha+ dendritic cells prolong the survival of vascularized heart allografts.","11751957",40]
["CD8alpha antigen","CD8alpha antigen","C431698","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21630253","The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.","21630253",40]
["cediranib","cediranib","C500926","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2007,"18320010","Defective differentiation of myeloid and plasmacytoid dendritic cells in advanced cancer patients is not normalized by tyrosine kinase inhibition of the vascular endothelial growth factor receptor.","18320010",40]
["Cefazolin","Cefazolin","D002437","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17223858","Protein binding of cefazolin is saturable in vivo both between and within patients.","17223858",40]
["Cefazolin","Cefazolin","D002437","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"932492","Protein binding and concentrations of cephaloridine and cefazolin in serum and interstitial fluid of dogs.","932492",40]
["Cefoperazone","Cefoperazone","D002438","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"6446398","Single-dose pharmacokinetics of cefoperazone following intravenous administration.","6446398",40]
["Cefotaxime","Cefotaxime","D002439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1986,"3540731","[Cefotiam, a new cephalosporin. Microbiological research, preliminary evaluation of its effect on phagocytosis and clinical multicenter research].","3540731",40]
["Cefotaxime","Cefotaxime","D002439","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1983,"6317911","[Postmarketing survey on the clinical use of cefotiam].","6317911",40]
["Ceftazidime","Ceftazidime","D002442","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2088186","Pharmacokinetics of ceftazidime in serum and suction blister fluid during continuous and intermittent infusions in healthy volunteers.","2088186",40]
["Ceftizoxime","Ceftizoxime","D015296","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"6296035","Comparative pharmacokinetics of ceftizoxime and other third-generation cephalosporins in humans.","6296035",40]
["Cefuroxime","Cefuroxime","D002444","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2001,"11590398","Effects of cefuroxime axetil on Staphylococcus aureus colonization and superantigen production in atopic dermatitis.","11590398",40]
["Celecoxib","Celecoxib","D000068579","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2004,"15237269","Acute generalized exanthematic pustulosis: a case and an overview of side effects affecting the skin caused by celecoxib and other COX-2 inhibitors reported so far.","15237269",40]
["Cellulose","Cellulose","D002482","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2002,"12568992","False positive endotoxin results in a DC product caused by (1--&gt;3)-beta-D-glucans acquired from a sterilizing cellulose filter.","12568992",40]
["Cellulose","Cellulose","D002482","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11488929","Cellulose-binding modules from extracellular matrix proteins of Dictyostelium discoideum stalk and sheath.","11488929",40]
["Cellulose","Cellulose","D002482","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15474046","Laccase from Melanocarpus albomyces binds effectively to cellulose.","15474046",40]
["Cellulose","Cellulose","D002482","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23784776","Increased enzyme binding to substrate is not necessary for more efficient cellulose hydrolysis.","23784776",40]
["Cellulose","Cellulose","D002482","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26616493","Engineering Cel7A carbohydrate binding module and linker for reduced lignin inhibition.","26616493",40]
["centaureidin","centaureidin","C083161","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1998,"9632366","Structure-activity requirements for flavone cytotoxicity and binding to tubulin.","9632366",40]
["Cephalexin","Cephalexin","D002506","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"11639","Chemical studies related to cephalosporin allergy. II. Competitive amine-catalyzed intra- and intermolecular aminolysis of cephalexin and cephaloglycin in aqueous solution.","11639",40]
["Cephalothin","Cephalothin","D002512","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4569661","Anomalous serum bactericidal activity.","4569661",40]
["Cetirizine","Cetirizine","D017332","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1997,"9412767","Maculopapular and urticarial eruption from cetirizine.","9412767",40]
["Cetirizine","Cetirizine","D017332","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"11030449","Activity of ebastine (10 and 20 mg) and cetirizine at 24 hours of a steady state treatment in the skin of healthy volunteers.","11030449",40]
["CGP 31523A","CGP 31523A","C044430","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6524904","In vitro activity of CGP 31523A, a broad-spectrum cephalosporin, in comparison with those of other agents.","6524904",40]
["Chalcone","Chalcone","D002599","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2014,"24067925","Antidepressant-like and anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa).","24067925",40]
["chelerythrine","chelerythrine","C016299","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26183621","Selective targeting of PPARγ by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency.","26183621",40]
["Chitin","Chitin","D002686","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10671445","Identification of a chitin-binding protein secreted by Pseudomonas aeruginosa.","10671445",40]
["Chitin","Chitin","D002686","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20714419","Chitin research revisited.","20714419",40]
["Chitin","Chitin","D002686","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8298282","Linkages between macromolecules in Candida albicans cell wall.","8298282",40]
["Chitosan","Chitosan","D048271","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,3,2016,"27187416","Effect of Chitosan Properties on Immunoreactivity.","27187416",40]
["Chitosan","Chitosan","D048271","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"20507705","Biocompatibility and growth of human keratinocytes and fibroblasts on biosynthesized cellulose-chitosan film.","20507705",40]
["Chitosan","Chitosan","D048271","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12800138","Optimal covalent immobilization of glucose oxidase-containing liposomes for highly stable biocatalyst in bioreactor.","12800138",40]
["Chitosan","Chitosan","D048271","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"22035370","Modification of cellulose films by adsorption of CMC and chitosan for controlled attachment of biomolecules.","22035370",40]
["Chitosan","Chitosan","D048271","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2008,"19186542","[Influence of chitosan on immunophenotype and functional activity of murine mononuclear leukocytes after immunization with inactivated influenza vaccine].","19186542",40]
["Chloral Hydrate","Chloral Hydrate","D002697","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1975,"806430","Warfarin interactions with chloral hydrate and glutethimide.","806430",40]
["Chloramphenicol","Chloramphenicol","D002701","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1962,"14034863","[Allergic dermatoses caused by chloramphenicol (chlorocid) therapy].","14034863",40]
["Chloramphenicol","Chloramphenicol","D002701","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1996,"8934079","Skin reactions due to eye drops: report of two cases.","8934079",40]
["Chloramphenicol","Chloramphenicol","D002701","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1973,"4365366","Identification of the chloramphenicol-binding protein in Escherichia coli ribosomes by partial reconstitution.","4365366",40]
["Chlorhexidine","Chlorhexidine","D002710","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2004,"15573648","Allergic contact dermatitis from chlorhexidine.","15573648",40]
["Chlorhexidine","Chlorhexidine","D002710","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1998,"9449513","Contact allergic dermatitis and life-threatening anaphylaxis to chlorhexidine.","9449513",40]
["chlorhexidine gluconate","chlorhexidine gluconate","C010882","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1996,"8895928","Local reactions to a chlorhexidine gluconate-impregnated antimicrobial dressing in very low birth weight infants.","8895928",40]
["chlorin","chlorin","C006969","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19464192","Peptide-conjugated chlorin-type photosensitizer binds neuropilin-1 in vitro and in vivo.","19464192",40]
["chloroacetamide","chloroacetamide","C013874","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1999,"10344489","Occupational allergic contact dermatitis from a glue, containing isothiazolinones and N-methylol-chloroacetamide, in a carpenter.","10344489",40]
["Chloroform","Chloroform","D002725","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7473860","Ketone potentiation of haloalkane-induced hepato- and nephrotoxicity. II. Implication of monooxygenases.","7473860",40]
["Chlorogenic Acid","Chlorogenic Acid","D002726","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2018,"29314466","Covalent bonding of Chlorogenic Acid induces structural modifications on sunflower proteins.","29314466",40]
["Chlorophyll","Chlorophyll","D002734","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25194026","The light-harvesting chlorophyll a/b binding proteins Lhcb1 and Lhcb2 play complementary roles during state transitions in Arabidopsis.","25194026",40]
["Chlorophyll","Chlorophyll","D002734","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1971,"5128170","Formation of two chlorophyll-protein complexes during greening of etiolated bean leaves.","5128170",40]
["chlorophyll a","chlorophyll a","C032081","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15304514","Early steps in the assembly of light-harvesting chlorophyll a/b complex: time-resolved fluorescence measurements.","15304514",40]
["Chloroquine","Chloroquine","D002738","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2015,"25889324","Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria.","25889324",40]
["Chloroquine","Chloroquine","D002738","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10191268","Inhibition of the peroxidative degradation of haem as the basis of action of chloroquine and other quinoline antimalarials.","10191268",40]
["chloroquine diphosphate","chloroquine diphosphate","C023676","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2004,"15689129","[The functional status of circulating lymphoid and phagocytic cells in patients with tropical malaria, living in the endemic areas of Guinea].","15689129",40]
["Chlorpheniramine","Chlorpheniramine","D002744","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2009,"19659969","Allergic contact dermatitis from dibucaine hydrochloride, chlorpheniramine maleate, and naphazoline hydrochloride in an over-the-counter topical antiseptic.","19659969",40]
["Chlorpromazine","Chlorpromazine","D002746","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1955,"13233054","Contact dermatitis from chlorpromazine; report of two cases.","13233054",40]
["Chlorpromazine","Chlorpromazine","D002746","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1978,"712593","Radioimmunoassay for psychotropic drugs I: synthesis and properties of haptens for chlorpromazine.","712593",40]
["Chlorpromazine","Chlorpromazine","D002746","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2543336","An attempt to reduce the photosensitizing potential of chlorpromazine with the simultaneous use of beta- and dimethyl-beta-cyclodextrins in guinea pigs.","2543336",40]
["Chlorthalidone","Chlorthalidone","D002752","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25899870","Simultaneous determination of azilsartan and chlorthalidone in rat and human plasma by liquid chromatography-electrospray tandem mass spectrometry.","25899870",40]
["Cholecalciferol","Cholecalciferol","D002762","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2000,"10687144","Vitamin D3 treatment to diminish the levels of immune suppressive CD34+ cells increases the effectiveness of adoptive immunotherapy.","10687144",40]
["Cholecalciferol","Cholecalciferol","D002762","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16908172","Synthesis and evaluation of a 3-position diastereomer of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 (ED-71).","16908172",40]
["Cholecalciferol","Cholecalciferol","D002762","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1969,"4305188","Metabolism and serum protein binding of 3H-vitamin D4 in vitamin D-resistant rickets.","4305188",40]
["Cholecalciferol","Cholecalciferol","D002762","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20194632","Evidence that vitamin D(3) promotes mast cell-dependent reduction of chronic UVB-induced skin pathology in mice.","20194632",40]
["Cholesterol","Cholesterol","D002784","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2015,"25646304","The combination of ISCOMATRIX adjuvant and TLR agonists induces regression of established solid tumors in vivo.","25646304",40]
["Cholesterol","Cholesterol","D002784","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2016,"26826307","Immune responses to vaccines delivered by encapsulation into and/or adsorption onto cationic lipid-PLGA hybrid nanoparticles.","26826307",40]
["Cholesterol","Cholesterol","D002784","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2001,"11518526","Cholesterol, a modulator of membrane-associated Abeta-fibrillogenesis and neurotoxicity.","11518526",40]
["Cholesterol","Cholesterol","D002784","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12591949","The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.","12591949",40]
["Cholesterol","Cholesterol","D002784","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14993927","Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.","14993927",40]
["Cholesterol","Cholesterol","D002784","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18408565","The effect of SLCO1B1*15 on the disposition of pravastatin and pitavastatin is substrate dependent: the contribution of transporting activity changes by SLCO1B1*15.","18408565",40]
["Cholesterol","Cholesterol","D002784","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"21289441","Guanidination of notexin alters its membrane-damaging activity in response to sphingomyelin and cholesterol.","21289441",40]
["Cholesterol","Cholesterol","D002784","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23315940","Hexosamine biosynthesis impairs insulin action via a cholesterolgenic response.","23315940",40]
["Cholesterol","Cholesterol","D002784","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25000142","Interaction of Alzheimer's β-amyloid peptides with cholesterol: mechanistic insights into amyloid pore formation.","25000142",40]
["Cholesterol","Cholesterol","D002784","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"29211995","Identification of Two New Cholesterol Interaction Sites on the A2A Adenosine Receptor.","29211995",40]
["Cholesterol","Cholesterol","D002784","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4777222","Electrical properties of black membranes from oxidized cholesterol and a strongly bound protein fraction of human erythrocyte membranes.","4777222",40]
["Cholesterol","Cholesterol","D002784","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6428456","Thermodynamics of lipid-protein association. Enthalphy of association of apolipoprotein A-II with dimyristoylphosphatidylcholine-cholesterol mixtures.","6428456",40]
["Cholesterol","Cholesterol","D002784","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1971,"5569944","Esterification of cholesterol by epidermis.","5569944",40]
["Cholesterol","Cholesterol","D002784","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17643927","Immunomodulation by statins: inhibition of cholesterol vs. isoprenoid biosynthesis.","17643927",40]
["cholesteryl sulfate","cholesteryl sulfate","C007045","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27551080","Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2.","27551080",40]
["Choline","Choline","D002794","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2016,"27288077","The Long and Winding Road: From the High-Affinity Choline Uptake Site to Clinical Trials for Malignant Brain Tumors.","27288077",40]
["Choline","Choline","D002794","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1978,"30801","Comparison of the secondary structures and binding sites of C-reactive protein and the phosphorylcholine-binding murine myeloma proteins.","30801",40]
["Chondroitin","Chondroitin","D002807","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1971,"4256063","Nature of the interaction of chondroitin 4-sulphate and chondroitin sulphate-proteoglycan with collagen.","4256063",40]
["chromic oxide","chromic oxide","C023600","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"21384495","Chromium(III) oxide nanoparticles induced remarkable oxidative stress and apoptosis on culture cells.","21384495",40]
["Cibacron Blue F 3GA","Cibacron Blue F 3GA","C012842","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"7138873","The presence of elements of a dinucleotide fold in UDP-glucose 4-epimerase from Saccharomyces fragilis.","7138873",40]
["ciclopirox","ciclopirox","C011585","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"24286179","Development of ciclopirox olamine topical formulations: evaluation of drug release, penetration and cutaneous retention.","24286179",40]
["ciglitazone","ciglitazone","C039671","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12594039","The genomic organization of mouse resistin reveals major differences from the human resistin: functional implications.","12594039",40]
["Cimetidine","Cimetidine","D002927","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2297356","Investigation of the mechanisms of the extensive excretion of cimetidine into rat milk.","2297356",40]
["Cimetidine","Cimetidine","D002927","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1986,"2936446","The effect of cimetidine on PBL from healthy donors and melanoma patients: augmentation of T cell responses to TCGF mitogens and alloantigens and of TCGF production.","2936446",40]
["cinnamic aldehyde","cinnamic aldehyde","C012843","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21936546","Synthesis of functionalized cinnamaldehyde derivatives by an oxidative Heck reaction and their use as starting materials for preparation of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.","21936546",40]
["Cinoxacin","Cinoxacin","D002937","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2752487","Protein binding of quinolonecarboxylic acids. I. Cinoxacin, nalidixic acid and pipemidic acid.","2752487",40]
["Ciprofloxacin","Ciprofloxacin","D002939","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2015,"24731770","DRESS syndrome induced by meropenem.","24731770",40]
["Cisplatin","Cisplatin","D002945","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2007,"17200373","Therapeutic synergy of human papillomavirus E7 subunit vaccines plus cisplatin in an animal tumor model: causal involvement of increased sensitivity of cisplatin-treated tumors to CTL-mediated killing in therapeutic synergy.","17200373",40]
["Cisplatin","Cisplatin","D002945","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,2013,"22826048","Occupational immediate-type allergic asthma due to potassium tetrachloroplatinate in production of cytotoxic drugs.","22826048",40]
["Cisplatin","Cisplatin","D002945","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19288144","Exploring metallodrug-protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound.","19288144",40]
["Cisplatin","Cisplatin","D002945","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22733664","Protein flexibility is key to cisplatin crosslinking in calmodulin.","22733664",40]
["Cisplatin","Cisplatin","D002945","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25993317","Phospholipase A2 inhibits cisplatin-induced acute kidney injury by modulating regulatory T cells by the CD206 mannose receptor.","25993317",40]
["Cisplatin","Cisplatin","D002945","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"7199395","The binding of platinum ethylenediamine dichloride to proteins, in vitro and in vivo.","7199395",40]
["Cisplatin","Cisplatin","D002945","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1989,"2791713","Drug selectivity and membrane transport properties of normal human lymphocytes.","2791713",40]
["Citric Acid","Citric Acid","D019343","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21989394","CcpA represses the expression of the divergent cit operons of Enterococcus faecalis through multiple cre sites.","21989394",40]
["citronella oil","citronella oil","C076730","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"8706410","Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract.","8706410",40]
["Clarithromycin","Clarithromycin","D017291","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,2001,"11449533","Immediate reaction to clarithromycin.","11449533",40]
["Clindamycin","Clindamycin","D002981","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2010,"20398826","Clindamycin-induced Sweet syndrome.","20398826",40]
["Clindamycin","Clindamycin","D002981","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23445168","Concentrations of clindamycin hydrochloride in homogenates of normal dog skin when administered at two oral dosage regimens.","23445168",40]
["Clobetasol","Clobetasol","D002990","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1992,"1618247","0.25% prednicarbate cream and the corresponding vehicle induce less skin atrophy than 0.1% betamethasone-17-valerate cream and 0.05% clobetasol-17-propionate cream.","1618247",40]
["Clobetasol","Clobetasol","D002990","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1995,"7774190","The influence of patch tests with clobetasol propionate on adjacent patch test reactions.","7774190",40]
["Clofibrate","Clofibrate","D002994","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7198457","Pharmacokinetic approach of plafibride in rat.","7198457",40]
["Clomiphene","Clomiphene","D002996","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4685498","Sequential changes in total and free testosterone and androstenedione in plasma during spontaneous and Clomid-induced ovulatory cycles.","4685498",40]
["Clonazepam","Clonazepam","D002998","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6732363","Pharmacokinetics of clonazepam in the dog.","6732363",40]
["Clonidine","Clonidine","D003000","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"25933958","Clonidine intensifies memantine cutaneous analgesia in response to local skin noxious pinprick in the rat.","25933958",40]
["Clostridium perfringens epsilon-toxin","Clostridium perfringens epsilon-toxin","C039811","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25485476","Interaction of Clostridium perfringens epsilon-toxin with biological and model membranes: A putative protein receptor in cells.","25485476",40]
["Clozapine","Clozapine","D003024","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9577836","Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors.","9577836",40]
["Coal","Coal","D003031","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2017,"28823652","PKC θ-mediated Ca2+/NF-AT signalling pathway may be involved in T-cell immunosuppression in coal-burning arsenic-poisoned population.","28823652",40]
["Coal Tar","Coal Tar","D003033","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2001,"11484907","Pharmacological coal tar induces G:C to T:A transversion mutations in the skin of muta mouse.","11484907",40]
["Cocaine","Cocaine","D003042","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1994,"7948538","Wasting associated with cocaine and heroin use in patients infected with human immunodeficiency virus.","7948538",40]
["Cocaine","Cocaine","D003042","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14519759","The human dopamine transporter forms a tetramer in the plasma membrane: cross-linking of a cysteine in the fourth transmembrane segment is sensitive to cocaine analogs.","14519759",40]
["Cocaine","Cocaine","D003042","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25100754","Relationship between cerebral sigma-1 receptor occupancy and attenuation of cocaine's motor stimulatory effects in mice by PD144418.","25100754",40]
["Cocaine","Cocaine","D003042","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9593100","Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain.","9593100",40]
["Coconut Oil","Coconut Oil","D000074263","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"28564614","Enhanced barrier functions and anti-inflammatory effect of cultured coconut extract on human skin.","28564614",40]
["Codeine","Codeine","D003061","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1958008","Cutaneous responses to histamine, compound 48/80, and codeine in patients with chronic renal failure.","1958008",40]
["coenzyme Q10","coenzyme Q10","C024989","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12734183","Reconstitution of recombinant uncoupling proteins: UCP1, -2, and -3 have similar affinities for ATP and are unaffected by coenzyme Q10.","12734183",40]
["Colchicine","Colchicine","D003078","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1975,"1056742","A reexamination of the reaction between colchicine and tubulin.","1056742",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C40195,B40195)","v":"Colchicine"},"Colchicine","D003078","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J40195,K40195)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2007,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q40195,Q40195)","v":"18041823"},"Luminescence studies of perturbation of tryptophan residues of tubulin in the complexes of tubulin with colchicine and colchicine analogues.","18041823",40]
["Colchicine","Colchicine","D003078","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1972,"4117007","Histamine release from human leukocytes: studies with deuterium oxide, colchicine, and cytochalasin B.","4117007",40]
["Colchicine","Colchicine","D003078","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8896903","Formylcolchicine bound to lactosaminated serum albumin is a more active antifibrotic agent than free colchicine.","8896903",40]
["Colchicine","Colchicine","D003078","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2014,"24881570","Discovery of structurally simplified analogs of colchicine as an immunosuppressant.","24881570",40]
["Collodion","Collodion","D003101","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7490453","An improved method to create nitrocellulose particles suitable for the immobilization of antigen and antibody.","7490453",40]
["concanamycin A","concanamycin A","C036978","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2000,"10733506","Granule exocytosis, and not the fas/fas ligand system, is the main pathway of cytotoxicity mediated by alloantigen-specific CD4(+) as well as CD8(+) cytotoxic T lymphocytes in humans.","10733506",40]
["Congo Red","Congo Red","D003224","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15974928","An Abeta sequestration approach using non-antibody Abeta binding agents.","15974928",40]
["copper bis(3,5-diisopropylsalicylate)","copper bis(3,5-diisopropylsalicylate)","C030865","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1987,"3500502","Copper(II)(3,5-diisopropylsalicylate)2 accelerates recovery of B and T cell reactivity following irradiation.","3500502",40]
["corchoionoside B","corchoionoside B","C105664","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1997,"9085554","Medicinal foodstuffs. V. Moroheiya. (1): Absolute stereostructures of corchoionosides A, B, and C, histamine release inhibitors from the leaves of Vietnamese Corchorus olitorius L. (Tiliaceae).","9085554",40]
["coumarin","coumarin","C030123","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23902929","Synthetic models related to methoxalen and menthofuran-cytochrome P450 (CYP) 2A6 interactions. benzofuran and coumarin derivatives as potent and selective inhibitors of CYP2A6.","23902929",40]
["CP 115953","CP 115953","C070116","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8390992","Exploiting mechanistic differences between drug classes to define functional drug interaction domains on topoisomerase II. Evidence that several diverse DNA cleavage-enhancing agents share a common site of action on the enzyme.","8390992",40]
["Cromolyn Sodium","Cromolyn Sodium","D004205","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,2,1973,"4149221","[Disodium cromoglycate (Lomudal). Clinical actions, indications and practical use in asthmatic lung diseases].","4149221",40]
["Cromolyn Sodium","Cromolyn Sodium","D004205","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"3146462","Contact dermatitis from sodium cromoglycate eyedrops.","3146462",40]
["Cromolyn Sodium","Cromolyn Sodium","D004205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6406905","Basophil variants with impaired cromoglycate binding do not respond to an immunological degranulation stimulus.","6406905",40]
["cryptococcal polysaccharide","cryptococcal polysaccharide","C014426","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2006,"17096589","Direct inhibition of T-cell responses by the Cryptococcus capsular polysaccharide glucuronoxylomannan.","17096589",40]
["cucurbit(7)uril","cucurbit(7)uril","C456276","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23510488","Enthalpic signature of methonium desolvation revealed in a synthetic host-guest system based on cucurbit[7]uril.","23510488",40]
["Curcumin","Curcumin","D003474","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2016,"27340353","Curcumin improves regulatory T cells in gut-associated lymphoid tissue of colitis mice.","27340353",40]
["Curcumin","Curcumin","D003474","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"22841393","Curcumin induces human cathelicidin antimicrobial peptide gene expression through a vitamin D receptor-independent pathway.","22841393",40]
["Curcumin","Curcumin","D003474","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19189206","Interaction of curcumin and diacetylcurcumin with the lipocalin member beta-lactoglobulin.","19189206",40]
["Curcumin","Curcumin","D003474","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28002947","A Carbocyclic Curcumin Inhibits Proliferation of Gram-Positive Bacteria by Targeting FtsZ.","28002947",40]
["Curcumin","Curcumin","D003474","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"25682767","Curcumin relieves TPA-induced Th1 inflammation in K14-VEGF transgenic mice.","25682767",40]
["Cyanamide","Cyanamide","D003484","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1997,"9267733","Drug eruption induced by cyanamide (carbimide): a clinical and histopathologic study of 7 patients.","9267733",40]
["cyanidin-3-O-beta-glucopyranoside","cyanidin-3-O-beta-glucopyranoside","C462279","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2004,"14743345","Effect of cyanidin 3-O-beta-glucopyranoside on micronucleus induction in cultured human lymphocytes by four different mutagens.","14743345",40]
["Cycloheximide","Cycloheximide","D003513","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1969,"5800129","Carcinogensis and inhibited biosynthesis of soluble mouse skin proteins by actidione.","5800129",40]
["cyclopentenone","cyclopentenone","C013905","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23355003","Increased generation of cyclopentenone prostaglandins after brain ischemia and their role in aggregation of ubiquitinated proteins in neurons.","23355003",40]
["Cyclophosphamide","Cyclophosphamide","D003520","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1977,"65425","Cyclophosphamide-induced specific suppression of the protective immune response to rodent malaria.","65425",40]
["Cyclophosphamide","Cyclophosphamide","D003520","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2009,"19417562","Anti-4-1BB scFv immunogene therapy and low dose cyclophosphamide exhibit a synergistic antitumor effect in established murine lung tumors.","19417562",40]
["Cyclophosphamide","Cyclophosphamide","D003520","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1987,"2884193","Changes in lymphocyte subsets after treatment with cyclophosphamide and during the development of contact sensitivity in the guinea pig.","2884193",40]
["Cyclophosphamide","Cyclophosphamide","D003520","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1979,"463564","Effects of cyclophosphamide on open, granulating skin wounds in rats.","463564",40]
["Cyclophosphamide","Cyclophosphamide","D003520","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2003,"12609827","Highly effective treatment of acquired immunodeficiency syndrome-related lymphoma with dose-adjusted EPOCH: impact of antiretroviral therapy suspension and tumor biology.","12609827",40]
["Cyclophosphamide","Cyclophosphamide","D003520","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"16733672","Low-dose cyclophosphamide modulates galectin-1 expression and function in an experimental rat lymphoma model.","16733672",40]
["Cyclophosphamide","Cyclophosphamide","D003520","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2017,"28855352","Low-Dose Cyclophosphamide Induces Antitumor T-Cell Responses, which Associate with Survival in Metastatic Colorectal Cancer.","28855352",40]
["Cyclophosphamide","Cyclophosphamide","D003520","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1979,"317907","The effects of cyclophosphamide on mitogen-induced and antibody-dependent cellular cytotoxicity in guinea pigs.","317907",40]
["Cyclophosphamide","Cyclophosphamide","D003520","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6819082","The effects of cyclophosphamide on in vitro cytotoxic responses to a syngeneic tumour.","6819082",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C42563,B42563)","v":"Cyclophosphamide"},"Cyclophosphamide","D003520","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J42563,K42563)","v":"T-Lymphocytes"},"D013601","T-Lymphocytes",1,3,1993,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q42563,Q42563)","v":"8439585"},"Humoral stimulating activities in post-cyclophosphamide rat sera and their purified fractions.","8439585",40]
["cyclopropane","cyclopropane","C030797","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23886812","Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: identification of an efficient lead for potent inhibitors of GABA transports.","23886812",40]
["Cystamine","Cystamine","D003538","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1968,"5689411","Some effects of binding agents on the x-irradiation of DNA.","5689411",40]
["cytisine","cytisine","C004712","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22553201","Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein.","22553201",40]
["cytolethal distending toxin","cytolethal distending toxin","C067044","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2001,"11238981","Campylobacter upsaliensis exerts a cytolethal distending toxin effect on HeLa cells and T lymphocytes.","11238981",40]
["Cytosine","Cytosine","D003596","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2013,"23677065","Formation of cyclobutane pyrimidine dimers at dipyrimidines containing 5-hydroxymethylcytosine.","23677065",40]
["Cytosine","Cytosine","D003596","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26546041","GADD45a physically and functionally interacts with TET1.","26546041",40]
["Dacarbazine","Dacarbazine","D003606","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2010,"19889936","Immunological factors relating to the antitumor effect of temozolomide chemoimmunotherapy in a murine glioma model.","19889936",40]
["Dacarbazine","Dacarbazine","D003606","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24675463","Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43.","24675463",40]
["Danazol","Danazol","D003613","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1992,"1387593","Erythema multiforme during danazol therapy.","1387593",40]
["danthron","danthron","C004315","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21084305","Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.","21084305",40]
["Dapsone","Dapsone","D003622","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1992,"1530873","Desensitization to dapsone in HIV-positive patients.","1530873",40]
["Darunavir","Darunavir","D000069454","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23403426","GRL-0519, a novel oxatricyclic ligand-containing nonpeptidic HIV-1 protease inhibitor (PI), potently suppresses replication of a wide spectrum of multi-PI-resistant HIV-1 variants in vitro.","23403426",40]
["Dasatinib","Dasatinib","D000069439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"17154512","2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor.","17154512",40]
["Daunorubicin","Daunorubicin","D003630","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1986,"3484557","Specific immunosuppression by immunotoxins containing daunomycin.","3484557",40]
["DC-S238","DC-S238","C000604575","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26390175","Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening.","26390175",40]
["DDT","DDT","D003634","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1987,"3318960","Sub-chronic effect of DDT on humoral immune response to a thymus-independent antigen (bacterial lipopolysaccharide) in mice.","3318960",40]
["DEET","DEET","D003671","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1983,"6851542","Contact urticaria to diethyltoluamide.","6851542",40]
["Deferoxamine","Deferoxamine","D003676","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23924612","Gram-positive siderophore-shuttle with iron-exchange from Fe-siderophore to apo-siderophore by Bacillus cereus YxeB.","23924612",40]
["dehydrosoyasaponin I","dehydrosoyasaponin I","C071764","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12208870","Different mechanisms underlying the stimulation of K(Ca) channels by nitric oxide and carbon monoxide.","12208870",40]
["delphinidin","delphinidin","C017185","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"16902416","Delphinidin, an anthocyanidin in pigmented fruits and vegetables, protects human HaCaT keratinocytes and mouse skin against UVB-mediated oxidative stress and apoptosis.","16902416",40]
["Dental Amalgam","Dental Amalgam","D003723","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1983,"6627922","Dermatitis from a chromium dental plate.","6627922",40]
["Dental Amalgam","Dental Amalgam","D003723","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22540268","Cutaneous amalgam tattoo in a dental professional: an unreported occupational argyria.","22540268",40]
["Deoxycholic Acid","Deoxycholic Acid","D003840","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2008,"18368492","The effect of retinoic acid and deoxycholic acid on the differentiation of primary human esophageal keratinocytes.","18368492",40]
["deoxynivalenol","deoxynivalenol","C007262","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"27389473","Deoxynivalenol induced mouse skin tumor initiation: Elucidation of molecular mechanisms in human HaCaT keratinocytes.","27389473",40]
["Deoxyribose","Deoxyribose","D003855","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15109568","Polyamine depletion switches the form of 2-deoxy-D-ribose-induced cell death from apoptosis to necrosis in HL-60 cells.","15109568",40]
["dermonecrotic toxin, Loxosceles intermedia","dermonecrotic toxin, Loxosceles intermedia","C516323","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"27563734","Potential Implications for Designing Drugs Against the Brown Spider Venom Phospholipase-D.","27563734",40]
["Desipramine","Desipramine","D003891","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2015,"26315493","Inhibitory effect of antidepressant drugs on contact hypersensitivity reaction is connected with their suppressive effect on NKT and CD8(+) T cells but not on TCR delta T cells.","26315493",40]
["Desipramine","Desipramine","D003891","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1998,"9778103","Effect of desipramine on immunological parameters in mice, and their reversal by stress.","9778103",40]
["Dexamethasone","Dexamethasone","D003907","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,1999,"10596698","Effects of theophylline, dexamethasone and salbutamol on cytokine gene expression in human peripheral blood CD4+ T-cells.","10596698",40]
["Dexamethasone","Dexamethasone","D003907","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2011,"20667622","Dexamethasone upregulates FOXP3 expression without increasing regulatory activity.","20667622",40]
["Dexamethasone","Dexamethasone","D003907","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2001,"11261790","Inhibition of glucocorticoid-mediated, caspase-independent dendritic cell death by CD40 activation.","11261790",40]
["Dexamethasone","Dexamethasone","D003907","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1963,"13950860","Injectable repository steroids in allergy.","13950860",40]
["Dexamethasone","Dexamethasone","D003907","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2003,"12797492","Glucocorticoid receptor-binding characteristics in severe asthma.","12797492",40]
["Dexamethasone","Dexamethasone","D003907","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"183058","A comparative study of receptors for natural and synthetic glucocorticoids in fetal rabbit lung.","183058",40]
["Dexamethasone","Dexamethasone","D003907","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2015,"26306445","Foreign Body Reaction to Subcutaneous Implants.","26306445",40]
["Dexamethasone","Dexamethasone","D003907","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23493372","Dexamethasone-mediated changes in adipose triacylglycerol metabolism are exaggerated, not diminished, in the absence of a functional GR dimerization domain.","23493372",40]
["Dexamethasone","Dexamethasone","D003907","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8648168","Epidermal barrier ontogenesis: maturation in serum-free media and acceleration by glucocorticoids and thyroid hormone but not selected growth factors.","8648168",40]
["Dexamethasone","Dexamethasone","D003907","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17227296","Spontaneous cell proliferation is associated with poor sensitivity to glucocorticoids in patients infected with HTLV.","17227296",40]
["Dexamethasone","Dexamethasone","D003907","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2012,"23047455","Accelerated antibody-mediated graft loss of rodent pancreatic islets after pretreatment with dexamethasone-treated immature donor dendritic cells.","23047455",40]
["Dexamethasone","Dexamethasone","D003907","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1987,"3498684","The effect of dexamethasone on growth and differentiation of bone-marrow derived mucosal mast cells in vitro.","3498684",40]
["Dexamethasone","Dexamethasone","D003907","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1996,"8865289","Early production of macrophage inflammatory protein-1 alpha occurs in respiratory distress syndrome and is associated with poor outcome.","8865289",40]
["Dexetimide","Dexetimide","D003909","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9487562","Unusual reduction of the in vitro skin permeation of [3H]dexetimide by atropine.","9487562",40]
["Dextran Sulfate","Dextran Sulfate","D016264","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1995,"7544748","Activated immunocompetent cells in rat colitis mucosa induced by dextran sulfate sodium and not complete but partial suppression of colitis by FK506.","7544748",40]
["diacetone glucose butyrate","diacetone glucose butyrate","C404264","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1999,"10638835","Stable prodrugs of n-butyric acid: suppression of T cell alloresponses in vitro and prolongation of heart allograft survival in a fully allogeneic rat strain combination.","10638835",40]
["diacetylfluorescein","diacetylfluorescein","C018506","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1996,"8906363","Indication that intracellular fluorescence polarization of T lymphocytes is cell cycle dependent.","8906363",40]
["Diazepam","Diazepam","D003975","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1448430","Studies on the excretion of diazepam and nordazepam into milk for the prediction of milk-to-plasma drug concentration ratios.","1448430",40]
["Diazepam","Diazepam","D003975","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3589146","Albumin as a potential membrane transport barrier for hepatic clearance of diazepam studied by a universal organ clearance approach.","3589146",40]
["diazepinomicin","diazepinomicin","C492422","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20655882","TLN-4601 peripheral benzodiazepine receptor (PBR/TSPO) binding properties do not mediate apoptosis but confer tumor-specific accumulation.","20655882",40]
["diazolidinylurea","diazolidinylurea","C044982","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"3378427","Contact allergy to diazolidinyl urea (Germall II).","3378427",40]
["dibenzacridine","dibenzacridine","C022289","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"11062160","Tumorigenicity of four optically active bay-region 3,4-diol 1, 2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice.","11062160",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C46083,B46083)","v":"Dibutyl Phthalate"},"Dibutyl Phthalate","D003993","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J46083,K46083)","v":"Dermatitis, Contact"},"D003877","Dermatitis, Contact",0,2,1975,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q46083,Q46083)","v":"1235308"},"Dibutyl phthalate sensitivity.","1235308",40]
["dichloro(4-isopropylbenzaldehyde thiosemicarbazone)cadmium(I)","dichloro(4-isopropylbenzaldehyde thiosemicarbazone)cadmium(I)","C121762","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1999,"10499288","Synthesis and characterization of complexes of p-isopropyl benzaldehyde and methyl 2-pyridyl ketone thiosemicarbazones with Zn(II) and Cd(II) metallic centers. Cytotoxic activity and induction of apoptosis in Pam-ras cells.","10499288",40]
["Diclofenac","Diclofenac","D004008","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11784137","Synthesis, structure, and activity of diclofenac analogues as transthyretin amyloid fibril formation inhibitors.","11784137",40]
["Diclofenac","Diclofenac","D004008","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26652101","Structural Insights into the Competitive Binding of Diclofenac and Naproxen by Equine Serum Albumin.","26652101",40]
["Diclofenac","Diclofenac","D004008","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23417751","Development of a codrug approach for sustained drug delivery across microneedle-treated skin.","23417751",40]
["Dicyclohexylcarbodiimide","Dicyclohexylcarbodiimide","D004024","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1979,"498780","Dicyclohexyl carbodiimide sensitivity.","498780",40]
["didecyldimethylammonium","didecyldimethylammonium","C027118","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2008,"18759880","Immediate-type allergy by occupational exposure to didecyl dimethyl ammonium chloride.","18759880",40]
["Diethyl Pyrocarbonate","Diethyl Pyrocarbonate","D004047","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1731613","Chemical modification of glucosamine-6-phosphate synthase by diethyl pyrocarbonate: evidence of histidine requirement for enzymatic activity.","1731613",40]
["Diethylcarbamazine","Diethylcarbamazine","D004049","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2000,"11127254","Tolerance to diethylcarbamazine-medicated salt in individuals infected with Onchocerca volvulus.","11127254",40]
["Diethylstilbestrol","Diethylstilbestrol","D004054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1971,"4326364","Effects of steroid conjugates on availability of pyridoxal phosphate for kynureninase and kynurenine aminotransferase activity.","4326364",40]
["Diethylstilbestrol","Diethylstilbestrol","D004054","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22888145","Prenatal exposure of mice to diethylstilbestrol disrupts T-cell differentiation by regulating Fas/Fas ligand expression through estrogen receptor element and nuclear factor-κB motifs.","22888145",40]
["diethyxime","diethyxime","C012284","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,1,1998,"9575415","[The mechanism of the effect of the cholinesterase reactivator diethyxime on different models of the development of delayed hypersensitivity in acute dichloroethane poisoning].","9575415",40]
["Digitoxin","Digitoxin","D004074","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1968,"5724007","The uptake of 3H-ouabain and 3H-digitoxin by guinea pig atria, previously extracted with glycerol.","5724007",40]
["Digoxigenin","Digoxigenin","D004076","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16388805","Dynamic force spectroscopy of the digoxigenin-antibody complex.","16388805",40]
["Digoxin","Digoxin","D004077","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4734270","Radioimmunoassay of plasma digoxin, with use of iodinated tracer.","4734270",40]
["Digoxin","Digoxin","D004077","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6862727","The quinidine-digoxin interaction in patients with impaired renal function.","6862727",40]
["digoxin-like factors","digoxin-like factors","C034504","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1988,"3390908","A digoxin-like factor associates with erythrocyte sodium concentration, sodium transport, and ouabain binding.","3390908",40]
["dihydrofolate","dihydrofolate","C010920","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2744204","A fluorescence study of substrate and inhibitor binding to bovine liver dihydrofolate reductase.","2744204",40]
["Dihydrostreptomycin Sulfate","Dihydrostreptomycin Sulfate","D004096","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"2414804","[Effects of aminoglycosides on T and B lymphocyte populations: in vitro study].","2414804",40]
["dihydroxy-vitamin D3","dihydroxy-vitamin D3","C118756","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"20691220","Primary effect of 1α,25(OH)₂D₃ on IL-10 expression in monocytes is short-term down-regulation.","20691220",40]
["diisopropylamine dichloroacetate","diisopropylamine dichloroacetate","C001002","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1999,"10545828","Effects of diisopropylamine dichloroacetate on proliferation and differentiation of normal human keratinocytes in vitro.","10545828",40]
["Diltiazem","Diltiazem","D004110","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1988,"2964858","Acute generalized exanthematous pustular dermatitis induced by diltiazem.","2964858",40]
["dimethisoquin","dimethisoquin","C009146","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1952,"14952029","Contact dermatitis due to quotane.","14952029",40]
["Dimethyl Fumarate","Dimethyl Fumarate","D000069462","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2011,"21545603","Correlation between lesion site and concentration of dimethyl fumarate in different parts of shoes in patients with contact dermatitis caused by dimethyl fumarate in footwear.","21545603",40]
["Dimethyl Sulfoxide","Dimethyl Sulfoxide","D004121","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17657708","Astressin-amide and astressin-acid are structurally different in dimethylsulfoxide.","17657708",40]
["Dimethyl Sulfoxide","Dimethyl Sulfoxide","D004121","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1950807","Dimethylsulfoxide (DMSO) for human single-stage intraoperative tissue expansion and circulatory enhancement.","1950807",40]
["dimethyldioctadecylammonium","dimethyldioctadecylammonium","C015831","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2001,"11457550","Lipophilic quaternary ammonium salt acts as a mucosal adjuvant when co-administered by the nasal route with vaccine antigens.","11457550",40]
["Dimethylnitrosamine","Dimethylnitrosamine","D004128","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6487369","Hepatic extraction of chenodeoxycholic acid in dogs chronically intoxicated with dimethylnitrosamine.","6487369",40]
["Dimyristoylphosphatidylcholine","Dimyristoylphosphatidylcholine","D004134","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1998,"9623764","The interaction of phospholipase A2 with liposomes: an immunological approach to its study.","9623764",40]
["Dinitrochlorobenzene","Dinitrochlorobenzene","D004137","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,3,2000,"10973687","Accessory cell populations in draining lymph nodes of lambs in the elicitation phase of DNCB-induced contact hypersensitivity.","10973687",40]
["Dinitrochlorobenzene","Dinitrochlorobenzene","D004137","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"7720373","Effect of allergic contact dermatitis on wound healing.","7720373",40]
["Dinitrochlorobenzene","Dinitrochlorobenzene","D004137","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1976,"325854","Immunotherapy with dinitrochlorobenzene (DNCB) for recurrent squamous cell tumor of conjunctiva.","325854",40]
["Dinitrochlorobenzene","Dinitrochlorobenzene","D004137","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1978,"273890","[Skin reactions to dinitrochlorobenzene in different clinical conditions in acute lymphoblastic leukemia in children].","273890",40]
["Dinitrochlorobenzene","Dinitrochlorobenzene","D004137","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1981,"6457866","Effect of murine tumors upon delayed hypersensitivity to dinitrochlorobenzene. III. In vivo activity of the nonspecific suppressor cell.","6457866",40]
["Dinitrofluorobenzene","Dinitrofluorobenzene","D004139","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15218036","Oligomerization of ribonuclease A: two novel three-dimensional domain-swapped tetramers.","15218036",40]
["Dinitrofluorobenzene","Dinitrofluorobenzene","D004139","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2016,"26642795","Percutaneous exposure to high-dose hapten induces systemic immunosuppression through the inhibition of dendritic cell migration.","26642795",40]
["Dinoprost","Dinoprost","D015237","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2007,"17697149","Prostaglandin metabolism in human hair follicle.","17697149",40]
["Dinoprostone","Dinoprostone","D015232","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1997,"9344500","Prostaglandin E2 and IL-4 provide naive CD4+ T cells with distinct inhibitory signals for the priming of IFN-gamma production.","9344500",40]
["Dinoprostone","Dinoprostone","D015232","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2004,"15219461","Inhibition of IL-6, TNF-alpha, and cyclooxygenase-2 protein expression by prostaglandin E2-induced IL-10 in bone marrow-derived dendritic cells.","15219461",40]
["Dinoprostone","Dinoprostone","D015232","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1990,"2317944","Depressed lymphocyte transformation and the role of prostaglandins in atopic dermatitis.","2317944",40]
["Dinoprostone","Dinoprostone","D015232","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2002,"12359631","Fructose-1,6-diphosphate attenuates prostaglandin E2 production and cyclo-oxygenase-2 expression in UVB-irradiated HaCaT keratinocytes.","12359631",40]
["Dinoprostone","Dinoprostone","D015232","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7542625","Prostaglandin E2 induces up-regulation of murine macrophage beta-endorphin receptors.","7542625",40]
["Dinoprostone","Dinoprostone","D015232","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1986,"2419709","Accumulation of cyclic 3',5'-adenosine monophosphate in cultured neonatal human dermal fibroblasts exposed to parathyroid hormone and prostaglandin E2.","2419709",40]
["Dinoprostone","Dinoprostone","D015232","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2002,"11751971","Prostaglandin E(2)-mediated activation of HIV-1 long terminal repeat transcription in human T cells necessitates CCAAT/enhancer binding protein (C/EBP) binding sites in addition to cooperative interactions between C/EBPbeta and cyclic adenosine 5'-monophosphate response element binding protein.","11751971",40]
["Dinoprostone","Dinoprostone","D015232","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1986,"3487685","Vitamin E supplementation suppresses prostaglandin E1(2) synthesis and enhances the immune response of aged mice.","3487685",40]
["Dinoprostone","Dinoprostone","D015232","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"7552777","Hypertonic/hyperoncotic fluids reverse prostaglandin E2 (PGE2)-induced T-cell suppression.","7552777",40]
["Diphenhydramine","Diphenhydramine","D004155","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1946,"21027120","Histamine antagonists; the effect of oral and local use of beta-dimethylamincethyl benzhydryl ether hydrochloride on the whealing due to histamine, antigen-antibody reactions, and other whealing mechanisms; therapeutic results in allergic manifestations.","21027120",40]
["Diphenhydramine","Diphenhydramine","D004155","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6705445","Diphenhydramine disposition in chronic liver disease.","6705445",40]
["diphenylcyclopropenone","diphenylcyclopropenone","C029402","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2001,"12092234","[Treatment of alopecia areata with diphencyprone].","12092234",40]
["Diphtheria Toxoid","Diphtheria Toxoid","D004168","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1970,"5492143","Disappearance of the delayed hypersensitivity reaction after intravenous antigen injection in the rat and guinea pig.","5492143",40]
["Diphtheria Toxoid","Diphtheria Toxoid","D004168","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21613460","Improved specificity of a multiplex immunoassay for quantitation of anti-diphtheria toxin antibodies with the use of diphtheria toxoid.","21613460",40]
["Dipyridamole","Dipyridamole","D004176","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1990,"2282202","The additive effect of certain drugs on the cyclosporine A inhibition of human T-cell proliferation. Studies using theophyllamine, warfarin, verapamil and dipyridamol.","2282202",40]
["Diquat","Diquat","D004178","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11562367","Opposite roles of selenium-dependent glutathione peroxidase-1 in superoxide generator diquat- and peroxynitrite-induced apoptosis and signaling.","11562367",40]
["Disopyramide","Disopyramide","D004206","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"7387819","Plasma binding of disopyramide.","7387819",40]
["Disperse Orange 1","Disperse Orange 1","C556349","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2011,"22653007","Textile dyes Disperse Orange 1 and Yellow 3 contain more than one allergen as shown by patch testing with thin-layer chromatograms.","22653007",40]
["Disulfiram","Disulfiram","D004221","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2016,"26948417","Facial allergic contact dermatitis without hand involvement caused by disposable latex gloves.","26948417",40]
["Dithiothreitol","Dithiothreitol","D004229","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3675570","Reversible oxidation of glyceraldehyde 3-phosphate dehydrogenase thiols in human lung carcinoma cells by hydrogen peroxide.","3675570",40]
["Ditiocarb","Ditiocarb","D004050","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1986,"3010015","Clinical characterization of imuthiol.","3010015",40]
["DMH1 compound","DMH1 compound","C583032","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23639540","Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probe.","23639540",40]
["docetaxel","docetaxel","C067311","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2001,"11705254","Cutaneous drug reaction case reports: from the world literature.","11705254",40]
["docetaxel","docetaxel","C067311","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11286326","Clinical pharmacokinetics of capecitabine.","11286326",40]
["dodecyltrimethylammonium","dodecyltrimethylammonium","C022806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6715307","Interaction of cationic detergents, cetyl- and dodecyl-trimethylammonium bromides, with lysozyme.","6715307",40]
["donepezil","donepezil","C076946","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2017,"27721157","Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease.","27721157",40]
["Dopamine","Dopamine","D004298","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11329058","The neurotransmitter dopamine inhibits angiogenesis induced by vascular permeability factor/vascular endothelial growth factor.","11329058",40]
["Dopamine","Dopamine","D004298","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14697776","Analogues of FAUC 73 revealing new insights into the structural requirements of nonaromatic dopamine D3 receptor agonists.","14697776",40]
["Dopamine","Dopamine","D004298","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16289323","Dopamine, oxytocin, and vasopressin receptor binding in the medial prefrontal cortex of monogamous and promiscuous voles.","16289323",40]
["Dopamine","Dopamine","D004298","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19514701","Selective binding of RNase B glycoforms by polydopamine-immobilized concanavalin A.","19514701",40]
["Dopamine","Dopamine","D004298","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21209197","Dopamine D2 receptor overexpression alters behavior and physiology in Drd2-EGFP mice.","21209197",40]
["Dopamine","Dopamine","D004298","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24832624","Endogenous neurotoxic dopamine derivative covalently binds to Parkinson's disease-associated ubiquitin C-terminal hydrolase L1 and alters its structure and function.","24832624",40]
["Dopamine","Dopamine","D004298","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"26645629","Binding Interactions of Dopamine and Apomorphine in D2High and D2Low States of Human Dopamine D2 Receptor Using Computational and Experimental Techniques.","26645629",40]
["Dopamine","Dopamine","D004298","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1970,"4318487","Tetrahydropapaveroline: an alkaloid metabolite of dopamine in vitro.","4318487",40]
["Dopamine","Dopamine","D004298","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1998,"9633189","[Comparative analysis of the action of antibodies to dopamine and serotonin on the functional activity of T- and B-lymphocytes and peritoneal macrophages].","9633189",40]
["Doxepin","Doxepin","D004316","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"12582408","Allergic contact dermatitis from topical doxepin: Food and Drug Administration's postmarketing surveillance experience.","12582408",40]
["Doxorubicin","Doxorubicin","D004317","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2003,"14724543","[Liposomal doxorubicin and palmoplantar erythrodysesthesia].","14724543",40]
["Doxorubicin","Doxorubicin","D004317","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1984,"6233126","Hypersensitivity reaction to doxorubicin.","6233126",40]
["Doxorubicin","Doxorubicin","D004317","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12213455","The disaccharide anthracycline MEN 10755 binds human serum albumin to a non-classical drug binding site.","12213455",40]
["Doxorubicin","Doxorubicin","D004317","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28272881","Role of Aromatic and Negatively Charged Residues of DrrB in Multisubstrate Specificity Conferred by the DrrAB System of Streptomyces peucetius.","28272881",40]
["Doxorubicin","Doxorubicin","D004317","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2002,"12045569","Treatment options in extravasation injury: an experimental study in rats.","12045569",40]
["Doxorubicin","Doxorubicin","D004317","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1980,"6970189","Doxorubicin and daunorubicin modulation of macrophages, T and B lymphocytes (anthracycline lymphocyte modulation).","6970189",40]
["Doxycycline","Doxycycline","D004318","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2018,"29489861","The Dox-pDC - A murine conditionally immortalized plasmacytoid dendritic cell line with native immune profile.","29489861",40]
["Dronabinol","Dronabinol","D013759","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11168391","delta(9)-Tetrahydrocannabinol increases nerve growth factor production by prostate PC-3 cells. Involvement of CB1 cannabinoid receptor and Raf-1.","11168391",40]
["Dronabinol","Dronabinol","D013759","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2017,"28104530","Long-lasting alterations of hippocampal GABAergic neurotransmission in adult rats following perinatal Δ9-THC exposure.","28104530",40]
["Dronabinol","Dronabinol","D013759","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1996,"8662742","Cannabinoid inhibition of adenylate cyclase-mediated signal transduction and interleukin 2 (IL-2) expression in the murine T-cell line, EL4.IL-2.","8662742",40]
["Duffy Blood-Group System","Duffy Blood-Group System","D004375","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18036613","Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface.","18036613",40]
["Durapatite","Durapatite","D017886","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20858015","Human common salivary protein 1 (CSP-1) promotes binding of Streptococcus mutans to experimental salivary pellicle and glucans formed on hydroxyapatite surface.","20858015",40]
["Dust","Dust","D004391","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2015,"26339029","Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells.","26339029",40]
["Dust","Dust","D004391","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1964,"14303760","[C-REACTIVE PROTEIN IN ALLERGIC SKIN DISEASES DUE TO CEMENT DUST].","14303760",40]
["Dust","Dust","D004391","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1982,"6126672","The house dust mite and atopic dermatitis.","6126672",40]
["Dust","Dust","D004391","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1987,"3313464","House dust sensitivity and environmental control.","3313464",40]
["Dust","Dust","D004391","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1993,"8224834","Nasal hyperreactivity and its effect on early and late sequelae of nasal challenge with house-dust mite extract.","8224834",40]
["E 3330","E 3330","C075569","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1998,"9551916","Nuclear targeted suppression of NF-kappa B activity by the novel quinone derivative E3330.","9551916",40]
["EBNA-3C, epstein-barr virus","EBNA-3C, epstein-barr virus","C498774","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18256156","Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein.","18256156",40]
["ebselen","ebselen","C042986","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1997,"9315318","Ebselen--an in vivo immune response modifier.","9315318",40]
["eckstolonol","eckstolonol","C507565","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2012,"22999063","Photo-oxidative stress by ultraviolet-B radiation and antioxidative defense of eckstolonol in human keratinocytes.","22999063",40]
["Edetic Acid","Edetic Acid","D004492","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1981,"6790568","Ethylenediaminetetraacetic acid (disodium salt)-labile bovine immunoglobulin M Fc binding to Brucella abortus: a cause of nonspecific agglutination.","6790568",40]
["Edetic Acid","Edetic Acid","D004492","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1995,"7623186","Topical application of 5-aminolevulinic acid, DMSO and EDTA: protoporphyrin IX accumulation in skin and tumours of mice.","7623186",40]
["efavirenz","efavirenz","C098320","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2009,"19748977","Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes.","19748977",40]
["Eicosapentaenoic Acid","Eicosapentaenoic Acid","D015118","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2005,"15753205","Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1.","15753205",40]
["Eicosapentaenoic Acid","Eicosapentaenoic Acid","D015118","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2006,"16133744","Polyunsaturated eicosapentaenoic acid changes lipid composition in lipid rafts.","16133744",40]
["Ellagic Acid","Ellagic Acid","D004610","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"20113347","Dietary compound ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation.","20113347",40]
["EMLA","EMLA","C036626","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"10625579","Effects on skin blood flow by provocation during local analgesia.","10625579",40]
["Emodin","Emodin","D004642","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21442678","Inhibition of experimental atopic dermatitis by rhubarb (rhizomes of Rheum tanguticum) and 5-lipoxygenase inhibition of its major constituent, emodin.","21442678",40]
["Enoxaparin","Enoxaparin","D017984","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,-1,1997,"9066940","Enoxaparin-associated dermal necrosis: a consequence of cross-reactivity with heparin-mediated antibodies.","9066940",40]
["enrofloxacin","enrofloxacin","C052904","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1994,"7520103","Effective treatment of mycoplasma contamination in cell lines with enrofloxacin (Baytril).","7520103",40]
["enterotoxin A, Staphylococcal","enterotoxin A, Staphylococcal","C026066","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,1997,"9300529","\"Bazinc\" instinct: how SEA attracts MHC class II molecules.","9300529",40]
["enterotoxin A, Staphylococcal","enterotoxin A, Staphylococcal","C026066","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2001,"11290341","Superantigen recognition by gammadelta T cells: SEA recognition site for human Vgamma2 T cell receptors.","11290341",40]
["enterotoxin A, Staphylococcal","enterotoxin A, Staphylococcal","C026066","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2010,"20116459","Staphylococcal enterotoxin A: Partial unfolding caused by high pressure or denaturing agents enhances superantigenicity.","20116459",40]
["enterotoxin A, Staphylococcal","enterotoxin A, Staphylococcal","C026066","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1995,"7822779","Inhibition of antigen-specific T cell activation by staphylococcal enterotoxins.","7822779",40]
["enterotoxin B, staphylococcal","enterotoxin B, staphylococcal","C031818","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2005,"16042784","A role for the Tec family kinase ITK in regulating SEB-induced interleukin-2 production in vivo via c-jun phosphorylation.","16042784",40]
["enterotoxin B, staphylococcal","enterotoxin B, staphylococcal","C031818","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1995,"8562515","ICAM-1 is required for T cell proliferation but not for anergy or apoptosis induced by Staphylococcus aureus enterotoxin B in vivo.","8562515",40]
["enterotoxin B, staphylococcal","enterotoxin B, staphylococcal","C031818","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2003,"14610492","Epicutaneous sensitization with superantigen induces allergic skin inflammation.","14610492",40]
["enterotoxin B, staphylococcal","enterotoxin B, staphylococcal","C031818","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24152989","Assessment of the functional regions of the superantigen staphylococcal enterotoxin B.","24152989",40]
["enterotoxin B, staphylococcal","enterotoxin B, staphylococcal","C031818","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2009,"19855072","The cellular and molecular immune response of the weanling piglet to staphylococcal enterotoxin B.","19855072",40]
["enterotoxin B, staphylococcal","enterotoxin B, staphylococcal","C031818","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2017,"28320831","Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology.","28320831",40]
["enterotoxin B, staphylococcal","enterotoxin B, staphylococcal","C031818","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1994,"8057748","The model of arthritis induced by superantigen in mice.","8057748",40]
["enterotoxin C, staphylococcal","enterotoxin C, staphylococcal","C034959","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23161916","Engineering a soluble high-affinity receptor domain that neutralizes staphylococcal enterotoxin C in rabbit models of disease.","23161916",40]
["enterotoxin E, Staphylococcal","enterotoxin E, Staphylococcal","C049463","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2583222","Activation of human T cells by toxic shock syndrome toxin-1: the toxin-binding structures expressed on human lymphoid cells acting as accessory cells are HLA class II molecules.","2583222",40]
["enterotoxin F, Staphylococcal","enterotoxin F, Staphylococcal","C030107","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28218671","Human scFvs That Counteract Bioactivities of Staphylococcus aureus TSST-1.","28218671",40]
["enterotoxin F, Staphylococcal","enterotoxin F, Staphylococcal","C030107","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2005,"15753253","Specific inhibitory action of anisodamine against a staphylococcal superantigenic toxin, toxic shock syndrome toxin 1 (TSST-1), leading to down-regulation of cytokine production and blocking of TSST-1 toxicity in mice.","15753253",40]
["enterotoxin F, Staphylococcal","enterotoxin F, Staphylococcal","C030107","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1988,"2830336","Toxic shock syndrome toxin-1 induces inositol phospholipid turnover, protein kinase C translocation, and calcium mobilization in human T cells.","2830336",40]
["enzacamene","enzacamene","C038939","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"17499903","Risk assessment of topically applied products.","17499903",40]
["Eosine Yellowish-(YS)","Eosine Yellowish-(YS)","D004801","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2001,"11244895","[Skin care in deep radiotherapy].","11244895",40]
["epibatidine","epibatidine","C082748","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25475645","Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4β2 and α3β4 subtypes.","25475645",40]
["epigallocatechin gallate","epigallocatechin gallate","C045651","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2004,"14672711","Epigallocatechin-3-gallate, constituent of green tea, suppresses the LPS-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and NF-kappaB.","14672711",40]
["epigallocatechin gallate","epigallocatechin gallate","C045651","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24590114","Differences in heat stability and ligand binding among β-lactoglobulin genetic variants A, B and C using (1)H NMR and fluorescence quenching.","24590114",40]
["epigallocatechin gallate","epigallocatechin gallate","C045651","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"16707481","(-)-Epigallocatechin-3-gallate prevents photocarcinogenesis in mice through interleukin-12-dependent DNA repair.","16707481",40]
["epigallocatechin gallate","epigallocatechin gallate","C045651","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2010,"20534878","Epigallocatechin-3-gallate directly suppresses T cell proliferation through impaired IL-2 utilization and cell cycle progression.","20534878",40]
["Epinephrine","Epinephrine","D004837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23306137","Radiotracers for cardiac sympathetic innervation: transport kinetics and binding affinities for the human norepinephrine transporter.","23306137",40]
["Epinephrine","Epinephrine","D004837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8980109","Amino acids of the alpha1B-adrenergic receptor involved in agonist binding: differences in docking catecholamines to receptor subtypes.","8980109",40]
["Epirubicin","Epirubicin","D015251","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2009,"18488220","Systemic immune effects of adjuvant chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide and/or radiotherapy in breast cancer: a longitudinal study.","18488220",40]
["Epoprostenol","Epoprostenol","D011464","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21339360","Beraprost enhances the APC function of B cells by upregulating CD86 expression levels.","21339360",40]
["Epoprostenol","Epoprostenol","D011464","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8790992","Effect of topical application of a stable prostacyclin analogue, SM-10902 on wound healing in diabetic mice.","8790992",40]
["Ergosterol","Ergosterol","D004875","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1996,"8647277","Possible nystatin-protein interaction in yeast plasma membrane vesicles in the presence of ergosterol. A Förster energy transfer study.","8647277",40]
["Erlotinib Hydrochloride","Erlotinib Hydrochloride","D000069347","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2007,"17725926","Epidermal growth factor receptor inhibitor-related folliculitis.","17725926",40]
["ertapenem","ertapenem","C446479","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24962030","Unbound fraction of ertapenem in intensive care unit patients.","24962030",40]
["Erythromycin","Erythromycin","D004917","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"8565504","Allergic contact dermatitis from erythromycin.","8565504",40]
["Erythromycin","Erythromycin","D004917","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1391680","Studies on the intravenous pharmacokinetics in rabbit and in vitro protein binding of two new salts of erythromycin: erythromycin maltobionate and erythromycin fumarate.","1391680",40]
["Escin","Escin","D004928","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"301389","Animal experiments on the question of the renal toleration of the horse chestnut saponin aescin.","301389",40]
["Estramustine","Estramustine","D004961","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7969073","Interaction of an estramustine photoaffinity analogue with cytoskeletal proteins in prostate carcinoma cells.","7969073",40]
["Ethanol","Ethanol","D000431","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2008,"17869084","Ethanol inhibits methionine adenosyltransferase II activity and S-adenosylmethionine biosynthesis and enhances caspase-3-dependent cell death in T lymphocytes: relevance to alcohol-induced immunosuppression.","17869084",40]
["Ethanol","Ethanol","D000431","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"20860616","Implications of ER stress, the unfolded protein response, and pro- and anti-apoptotic protein fingerprints in human monocyte-derived dendritic cells treated with alcohol.","20860616",40]
["Ethanol","Ethanol","D000431","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,2000,"11003205","Anti-interleukin-6 antibody treatment restores cell-mediated immune function in mice with acute ethanol exposure before burn trauma.","11003205",40]
["Ethanol","Ethanol","D000431","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"18923141","UNC-18 modulates ethanol sensitivity in Caenorhabditis elegans.","18923141",40]
["Ethanol","Ethanol","D000431","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23817978","Tryptophan 46 is a site for ethanol and ivermectin action in P2X4 receptors.","23817978",40]
["Ethanol","Ethanol","D000431","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1976,"1085164","The effect of ethanol on ion transport in frog skin.","1085164",40]
["Ethanol","Ethanol","D000431","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22594656","The effects of alcohol on the metabolism and toxicology of anti-psoriasis drugs.","22594656",40]
["Ethanol","Ethanol","D000431","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1999,"10549999","Ethanol-altered liver-associated T cells mediate liver injury in rats administered Concanavalin A (Con A) or lipopolysaccharide (LPS).","10549999",40]
["Ethanol","Ethanol","D000431","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1998,"9581645","Influence of ethanol consumption on immune competence of adult animals exposed to ethanol in utero.","9581645",40]
["Ethionamide","Ethionamide","D005000","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2017,"28302858","Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.","28302858",40]
["ethyl fumarate","ethyl fumarate","C061175","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8800297","The effect of fumaric acid esters and dithranol on acanthosis and hyperproliferation in psoriasis vulgaris.","8800297",40]
["ethyl sebacate","ethyl sebacate","C029410","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1997,"9145279","Allergic contact dermatitis due to diethyl sebacate.","9145279",40]
["ethylene","ethylene","C036216","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9808731","A nitrilase-like protein interacts with GCC box DNA-binding proteins involved in ethylene and defense responses.","9808731",40]
["ethylene dimethacrylate","ethylene dimethacrylate","C004919","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19100614","Via zinc(II) protoporphyrin to the synthesis of poly(ZnPP-MAA-EGDMA) for the imprinting and selective binding of bilirubin.","19100614",40]
["Ethylene Oxide","Ethylene Oxide","D005027","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1984,"6236041","Ethylene oxide dermatitis.","6236041",40]
["Ethylmaleimide","Ethylmaleimide","D005033","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11171069","Cysteine residues in the D-galactose-H+ symport protein of Escherichia coli: effects of mutagenesis on transport, reaction with N-ethylmaleimide and antibiotic binding.","11171069",40]
["Ethylmaleimide","Ethylmaleimide","D005033","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1988,"3409268","Effects of the sulfhydryl reagent N-ethylmaleimide on reserpine binding to the catecholamine transporter in chromaffin granule membranes.","3409268",40]
["Etidocaine","Etidocaine","D005041","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"598408","Disposition and placental transfer of etidocaine in pregnancy.","598408",40]
["etisazole","etisazole","C027996","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1980,"7438745","Etisazole: an animal antifungal agent with skin sensitizing properties in man.","7438745",40]
["Etomidate","Etomidate","D005045","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2017,"28337880","Effects of anesthesia using propofol and etomidate on T lymphocyte subpopulation of infectious shock patients in perioperative period.","28337880",40]
["Etoposide","Etoposide","D005047","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9923567","Relation between unbound plasma concentrations and toxicity in a prolonged oral etoposide schedule.","9923567",40]
["etoricoxib","etoricoxib","C422649","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,2011,"21834936","Response to a selective COX-2 inhibitor in patients with urticaria/angioedema induced by nonsteroidal anti-inflammatory drugs.","21834936",40]
["eucalyptol","eucalyptol","C010087","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2011,"21450899","Curcumin, myrecen and cineol modulate the percentage of lymphocyte subsets altered by 2,3,7, 8-tetracholorodibenzo-p-dioxins (TCDD) in rats.","21450899",40]
["Eugenol","Eugenol","D005054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24014106","Effects of eugenol on T-type Ca2+ channel isoforms.","24014106",40]
["eupatilin","eupatilin","C045325","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2009,"19565564","Eupatilin inhibits T-cell activation by modulation of intracellular calcium flux and NF-kappaB and NF-AT activity.","19565564",40]
["fanasil, pyrimethamine drug combination","fanasil, pyrimethamine drug combination","C001205","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1990,"2138674","Serious adverse drug reactions to pyrimethamine-sulphadoxine, pyrimethamine-dapsone and to amodiaquine in Britain.","2138674",40]
["Farnesol","Farnesol","D005204","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17640272","Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa.","17640272",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C57539,B57539)","v":"fenamiphos"},"fenamiphos","C002698","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J57539,K57539)","v":"Skin"},"D012867","Skin",0,1,1986,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q57539,Q57539)","v":"3742068"},"Estimating the hazard to humans applying Nemacur 3EC with rat dermal-dose ChE response data.","3742068",40]
["Fenitrothion","Fenitrothion","D005278","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1996,"8921343","Immunotoxicological insignificance of fenitrothion in mice and rats.","8921343",40]
["Fentanyl","Fentanyl","D005283","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2015,"25588572","Development of a peptidomimetic antagonist of neuropeptide FF receptors for the prevention of opioid-induced hyperalgesia.","25588572",40]
["Fentanyl","Fentanyl","D005283","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2002,"11772808","Intravenous fentanyl increases natural killer cell cytotoxicity and circulating CD16(+) lymphocytes in humans.","11772808",40]
["Feprazone","Feprazone","D011298","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1993,"8458203","Contact dermatitis from feprazone.","8458203",40]
["ferric oxide","ferric oxide","C000499","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"26090418","Effect of Fe3O4 Nanoparticles on Skin Tumor Cells and Dermal Fibroblasts.","26090418",40]
["ferrocene","ferrocene","C004998","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1999,"10420571","Evaluation of genotoxic and immunotoxic activities of potential glucose biosensor components: ferrocenes.","10420571",40]
["ferumoxides","ferumoxides","C065507","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2011,"21637760","Monitoring of in vivo function of superparamagnetic iron oxide labelled murine dendritic cells during anti-tumour vaccination.","21637760",40]
["Ficoll","Ficoll","D005362","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1984,"6201291","Hapten-Ficoll conjugates induce T-cell-dependent IgM anti-hapten responses and T cells mediating hapten-specific delayed-type hypersensitivity.","6201291",40]
["Ficusin","Ficusin","D005363","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1977,"915742","Preparation and skin-photosensitizing activity of substituted psoralens.","915742",40]
["Fingolimod Hydrochloride","Fingolimod Hydrochloride","D000068876","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2011,"20702533","CD4+ CD25+ regulatory T cells partially mediate the beneficial effects of FTY720, a sphingosine-1-phosphate analogue, during ischaemia/reperfusion-induced acute kidney injury.","20702533",40]
["Fingolimod Hydrochloride","Fingolimod Hydrochloride","D000068876","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"11950011","Effects of FTY720 in MRL-lpr/lpr mice: therapeutic potential in systemic lupus erythematosus.","11950011",40]
["Firefly Luciferin","Firefly Luciferin","D049454","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12950169","A mutagenesis study of the putative luciferin binding site residues of firefly luciferase.","12950169",40]
["FLA 99","FLA 99","C079651","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1995,"7623516","The effects of two inositol (1,4,5)-trisphosphate 5-phosphatase inhibitors on thyrotropin releasing hormone stimulated inositol (1,4,5)-trisphosphate production in GH3 cells.","7623516",40]
["Flecainide","Flecainide","D005424","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"3898035","Flecainide: a new prototype antiarrhythmic agent.","3898035",40]
["Fluconazole","Fluconazole","D015725","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28979038","Antifungal Extraction by the Extracorporeal Membrane Oxygenation Circuit.","28979038",40]
["Flufenamic Acid","Flufenamic Acid","D005439","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,1982,"7173741","[Anti-inflammatory and analgesic activities of a trans-cutaneous non-steroidal anti-inflammatory agent, etofenamate gel].","7173741",40]
["Fluocinolone Acetonide","Fluocinolone Acetonide","D005446","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,1966,"5342507","[Flubenisolonvalerate and fluocinolonacetonide in the treatment of skin diseases. A double-blind study].","5342507",40]
["Fluocinolone Acetonide","Fluocinolone Acetonide","D005446","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"26049018","Design, characterization and skin permeating potential of Fluocinolone acetonide loaded nanostructured lipid carriers for topical treatment of psoriasis.","26049018",40]
["Fluocortolone","Fluocortolone","D005448","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1994,"7842695","Allergic contact dermatitis from fluocortin butylester.","7842695",40]
["Fluorescein","Fluorescein","D019793","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2002,"12405878","The prediction of human skin responses by using the combined in vitro fluorescein leakage/Alamar Blue (resazurin) assay.","12405878",40]
["Fluorescein-5-isothiocyanate","Fluorescein-5-isothiocyanate","D016650","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2000,"10937574","IFN-gamma and LPS-mediated IL-10-dependent suppression of retinal microglial activation.","10937574",40]
["Fluorescein-5-isothiocyanate","Fluorescein-5-isothiocyanate","D016650","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1988,"2457917","Automatic microinjection system facilitates detection of growth inhibitory mRNA.","2457917",40]
["Fluorodeoxyglucose F18","Fluorodeoxyglucose F18","D019788","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2017,"28394841","Blastic Plasmacytoid Dendritic Cell Neoplasm Evaluated by FDG PET/CT.","28394841",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C59139,B59139)","v":"Fluorouracil"},"Fluorouracil","D005472","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J59139,K59139)","v":"CD4-Positive T-Lymphocytes"},"D015496","CD4-Positive T-Lymphocytes",1,1,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q59139,Q59139)","v":"16224030"},"5-Fluorouracil infusion reduces gut-associated lymphoid tissue cell number and mucosal immunoglobulin A levels.","16224030",40]
["Fluorouracil","Fluorouracil","D005472","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1997,"9291822","Hand-foot syndrome induced by high-dose, short-term, continuous 5-fluorouracil infusion.","9291822",40]
["Fluorouracil","Fluorouracil","D005472","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25612933","Probing the anticancer-drug-binding-induced microenvironment alterations in subdomain IIA of human serum albumin.","25612933",40]
["Fluorouracil","Fluorouracil","D005472","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1980,"6972072","Differences in chemotherapeutic susceptibility of human T-, B-, and non-T-/non-B-lymphocytes in culture.","6972072",40]
["Fluoxetine","Fluoxetine","D005473","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2002,"12464452","R-fluoxetine increases extracellular DA, NE, as well as 5-HT in rat prefrontal cortex and hypothalamus: an in vivo microdialysis and receptor binding study.","12464452",40]
["Flurbiprofen","Flurbiprofen","D005480","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16028901","Triplet excited States as chiral reporters for the binding of drugs to transport proteins.","16028901",40]
["flurbiprofen axetil","flurbiprofen axetil","C504422","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2016,"25537338","A novel injection strategy of flurbiprofen axetil by inhibiting protein binding with 6-methoxy-2-naphthylacetic acid.","25537338",40]
["Fluticasone","Fluticasone","D000068298","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2008,"18699801","Effects of inhaled fluticasone propionate on CTLA-4-positive CD4+CD25+ cells in induced sputum in mild asthmatics.","18699801",40]
["Folic Acid","Folic Acid","D005492","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1991,"1680150","Folic acid absorption in patients infected with the human immunodeficiency virus.","1680150",40]
["Folic Acid","Folic Acid","D005492","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1997,"9187851","Linear IgA bullous dermatosis after contact with sodium hypochlorite.","9187851",40]
["Folic Acid","Folic Acid","D005492","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18804700","Methyltetrahydrofolate in folate-binding protein glycine N-methyltransferase.","18804700",40]
["Folic Acid","Folic Acid","D005492","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22424148","Fragment-based design of symmetrical bis-benzimidazoles as selective inhibitors of the trimethoprim-resistant, type II R67 dihydrofolate reductase.","22424148",40]
["Folic Acid","Folic Acid","D005492","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26494420","Virtual screening, docking, and dynamics of potential new inhibitors of dihydrofolate reductase from Yersinia pestis.","26494420",40]
["Folic Acid","Folic Acid","D005492","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1971,"4943575","Folate inhibitors: a structure-activity analysis using linear modeling.","4943575",40]
["Folic Acid","Folic Acid","D005492","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"6170","Determination of erythrocyte folate by competitive protein binding assay preceded by extraction.","6170",40]
["Folic Acid","Folic Acid","D005492","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1983,"6825121","Phase I trial of 10-deaza-aminopterin in patients with advanced cancer.","6825121",40]
["fondaparinux","fondaparinux","C438268","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2017,"27766660","A rare cutaneous manifestation of hemorrhagic bullae to low-molecular-weight heparin and fondaparinux: report of two cases.","27766660",40]
["Formaldehyde","Formaldehyde","D005557","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1965,"14255685","CHEMICAL AND IMMUNOLOGICAL COMPOSITION OF SURFACE STRUCTURES OF LISTERIA MONOCYTOGENES.","14255685",40]
["Formaldehyde","Formaldehyde","D005557","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2017,"28444762","Screening allergic reactions to resol resin based on phenol and formaldehyde in a clinic of occupational dermatology.","28444762",40]
["Formaldehyde","Formaldehyde","D005557","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1953,"13081257","[Occupational dermatoses in fabric-finishing processes].","13081257",40]
["Formaldehyde","Formaldehyde","D005557","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1986,"2944733","[Tolerance of a hemorrhoid ointment in patients allergic to formaldehyde].","2944733",40]
["Formaldehyde","Formaldehyde","D005557","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22610548","Advancing formaldehyde cross-linking towards quantitative proteomic applications.","22610548",40]
["Formaldehyde","Formaldehyde","D005557","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2788599","[Significance of immunocytochemical indices of body reactivity of workers engaged in the production of carbonic plastics on the base of formaldehyde-containing and epoxide resins].","2788599",40]
["fosbretabulin","fosbretabulin","C058728","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12663938","Evaluation of antimitotic agents by quantitative comparisons of their effects on the polymerization of purified tubulin.","12663938",40]
["Fosfomycin","Fosfomycin","D005578","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21216609","Synthesis and evaluation of phosphonated N-heteroarylcarboxamides as DOXP-reductoisomerase (DXR) inhibitors.","21216609",40]
["Freund's Adjuvant","Freund's Adjuvant","D005620","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1963,"14054751","[MULTIPLE SCLEROSIS-AN IMMUNOLOGICAL PROBLEM].","14054751",40]
["Freund's Adjuvant","Freund's Adjuvant","D005620","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1964,"14185387","[APROPOS OF INDUCTION OF \"ALLERGIC POLYNEURITIS\" IN RABBITS WITH SCHWANN CELL TISSUE CULTURE ANTIGEN].","14185387",40]
["Freund's Adjuvant","Freund's Adjuvant","D005620","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1967,"4179299","[Comparative study of the adjuvant action of bacterial endotoxins. I. Evaluation of the adjuvant activity of endoperitoneal administration of endotoxins, Fruend adjuvant and RNA in mice].","4179299",40]
["Freund's Adjuvant","Freund's Adjuvant","D005620","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"7558513","Different T-cell activation by streptozotocin and Freund's adjuvant in popliteal lymph node (PLN).","7558513",40]
["Fructose","Fructose","D005632","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"17125255","Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.","17125255",40]
["fucoidan","fucoidan","C007789","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10694379","Fucoidan-dependent conformational changes in annexin II tetramer.","10694379",40]
["fucolipids","fucolipids","C025567","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10640390","Kinetic analysis of the binding of Ulex europeas agglutinin 1 (UEA 1) to H-antigenic fucolipid.","10640390",40]
["Fucose","Fucose","D005643","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1978,"680922","Serum protein bound fucose in diagnosis of breast malignancy.","680922",40]
["FuGene","FuGene","C411955","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2003,"12757621","Effect of cytofectins on the immune response of murine macrophages to mammalian DNA.","12757621",40]
["fumonisin B1","fumonisin B1","C056933","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2000,"10996037","Activation of rat splenic macrophage and lymphocyte functions by fumonisin B1.","10996037",40]
["Furosemide","Furosemide","D005665","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26820767","Purification and Characterization of Glucose 6-Phosphate Dehydrogenase, 6-Phosphogluconate Dehydrogenase, and Glutathione Reductase from Rat Heart and Inhibition Effects of Furosemide, Digoxin, and Dopamine on the Enzymes Activities.","26820767",40]
["Furosemide","Furosemide","D005665","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"7176178","[Impaired plasma protein binding of furosemide in nephrotic syndrome and uremia].","7176178",40]
["Fusidic Acid","Fusidic Acid","D005672","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1970,"4991433","[Penetration of fusidic acid into aseptic bone tissue].","4991433",40]
["G(M1) Ganglioside","G(M1) Ganglioside","D005677","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2006,"16818778","GM1 binding-deficient exotoxin is a potent noninflammatory broad spectrum intradermal immunoadjuvant.","16818778",40]
["G(M1) Ganglioside","G(M1) Ganglioside","D005677","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12681284","Imaging metabolism of phosphatidylinositol 4,5-bisphosphate in T-cell GM1-enriched domains containing Ras proteins.","12681284",40]
["G(M1) Ganglioside","G(M1) Ganglioside","D005677","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2004,"15085197","Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus.","15085197",40]
["G(M1) Ganglioside","G(M1) Ganglioside","D005677","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1986,"2877886","Two natural killer cell populations which belong to T cell lineage in nude mice.","2877886",40]
["G(M3) Ganglioside","G(M3) Ganglioside","D005679","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2006,"16675488","Melanoma-derived gangliosides impair migratory and antigen-presenting function of human epidermal Langerhans cells and induce their apoptosis.","16675488",40]
["gadodiamide","gadodiamide","C064925","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2007,"17627792","Nephrogenic systemic fibrosis: a case series suggesting gadolinium as a possible aetiological factor.","17627792",40]
["gadoterate meglumine","gadoterate meglumine","C072417","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21826007","Gadolinium contrast agent associated stimulation of human fibroblast collagen production.","21826007",40]
["Galactose","Galactose","D005690","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12382235","Terminal alpha-linked galactose rather than N-acetyl lactosamine is ligand for bovine heart galectin-1 in N-linked oligosaccharides of glycoproteins.","12382235",40]
["Galactose","Galactose","D005690","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17262177","Galactose-specific fimbrial adhesin of enteroaggregative Escherichia coli: a possible aggregative factor.","17262177",40]
["Galactose","Galactose","D005690","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4618738","The properties of the galactose-binding protein, the possible chemoreceptor for galactose chemotaxis in Escherichia coli.","4618738",40]
["galactosyl-(1,4)-fucopyranosyl-(1,3)-N-acetylglucosamine","galactosyl-(1,4)-fucopyranosyl-(1,3)-N-acetylglucosamine","C110530","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15845541","Selective binding of the scavenger receptor C-type lectin to Lewisx trisaccharide and related glycan ligands.","15845541",40]
["Galantamine","Galantamine","D005702","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11172080","Galantamine: effect on nicotinic receptor binding, acetylcholinesterase inhibition, and learning.","11172080",40]
["Gallic Acid","Gallic Acid","D005707","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1987,"2963726","Allergic contact dermatitis to propyl gallate.","2963726",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C62659,B62659)","v":"Gallic Acid"},"Gallic Acid","D005707","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J62659,K62659)","v":"Skin"},"D012867","Skin",0,1,2017,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q62659,Q62659)","v":"28064008"},"Functional response of novel bioprotective poloxamer-structured vesicles on inflamed skin.","28064008",40]
["gamma-Tocopherol","gamma-Tocopherol","D024504","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25689347","Exploitation of the ability of γ-tocopherol to facilitate membrane co-localization of Akt and PHLPP1 to develop PHLPP1-targeted Akt inhibitors.","25689347",40]
["Ganciclovir","Ganciclovir","D015774","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"10852616","Prolonged allograft survival through conditional and specific ablation of alloreactive T cells expressing a suicide gene.","10852616",40]
["ganglioside, GD2","ganglioside, GD2","C019403","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"23134699","Ganglioside GD2-specific trifunctional surrogate antibody Surek demonstrates therapeutic activity in a mouse melanoma model.","23134699",40]
["ganglioside, GD3","ganglioside, GD3","C026226","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1999,"10547417","Comparison of the effect of different immunological adjuvants on the antibody and T-cell response to immunization with MUC1-KLH and GD3-KLH conjugate cancer vaccines.","10547417",40]
["ganglioside, GM4","ganglioside, GM4","C028253","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17499534","Ganglioside from eel serum high density lipoprotein (HDL) and its role as a ligand for HDL binding protein.","17499534",40]
["gefitinib","gefitinib","C419708","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2014,"25228008","Gefitinib induces cytoplasmic translocation of the CDK inhibitor p27 and its binding to a cleaved intermediate of caspase 8 in non-small cell lung cancer cells.","25228008",40]
["gellan gum","gellan gum","C048288","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2015,"26079831","In vitro and in vivo ocular safety and eye surface permanence determination by direct and Magnetic Resonance Imaging of ion-sensitive hydrogels based on gellan gum and kappa-carrageenan.","26079831",40]
["Genistein","Genistein","D019833","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"18215507","Topical treatment with (-)-epigallocatechin-3-gallate and genistein after a single UV exposure can reduce skin damage.","18215507",40]
["Gentian Violet","Gentian Violet","D005840","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"2972522","Dermatitis from crystal violet.","2972522",40]
["geranylgeranic acid","geranylgeranic acid","C040155","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28455099","Membrane localization and dynamics of geranylgeranylated Rab5 hypervariable region.","28455099",40]
["ginsenoside M1","ginsenoside M1","C112772","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2014,"24834979","Immunosuppressive effect of compound K on islet transplantation in an STZ-induced diabetic mouse model.","24834979",40]
["ginsenoside Rg1","ginsenoside Rg1","C035054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2017,"28605639","Ginsenoside Rg1 attenuates the inflammatory response in DSS-induced mice colitis.","28605639",40]
["Glipizide","Glipizide","D005913","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25912461","Analysis of glipizide binding to normal and glycated human serum albumin by high-performance affinity chromatography.","25912461",40]
["globotriaosylceramide","globotriaosylceramide","C018549","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19212418","Detergent-resistant globotriaosyl ceramide may define verotoxin/glomeruli-restricted hemolytic uremic syndrome pathology.","19212418",40]
["glucopyranosyl lipid-A","glucopyranosyl lipid-A","C000608161","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2017,"28679495","Dose Selection for an Adjuvanted Respiratory Syncytial Virus F Protein Vaccine for Older Adults Based on Humoral and Cellular Immune Responses.","28679495",40]
["Glucosamine","Glucosamine","D005944","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1966,"5956635","The metabolism of plasma glycoproteins. II. Studies on the rate of incorporation of glucosamine-1-14C into protein-bound hexosamine in the rat bearing Walker 256 carcinoma.","5956635",40]
["Glucosamine","Glucosamine","D005944","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1981,"6260860","Lysis of target cells infected with vesicular stomatitis virus (VSV) in the presence of tunicamycin by anti-VSV cytotoxic T lymphocytes.","6260860",40]
["Glucose","Glucose","D005947","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1967,"4232422","Studies on the mechanism of delayed type hypersensitivity in tissue cultures. IX. The effect of glucose concentration on the reaction of delayed type hypersensitivity in tissue cultures.","4232422",40]
["Glucose","Glucose","D005947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10749686","Conserved arginine-516 of Penicillium amagasakiense glucose oxidase is essential for the efficient binding of beta-D-glucose.","10749686",40]
["Glucose","Glucose","D005947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12672794","A novel function for a glucose analog of blood group H antigen as a mediator of leukocyte-endothelial adhesion via intracellular adhesion molecule 1.","12672794",40]
["Glucose","Glucose","D005947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17692316","High glucose enhances MMP-2 production in adventitial fibroblasts via Akt1-dependent NF-kappaB pathway.","17692316",40]
["Glucose","Glucose","D005947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19537755","Fluorescence emission and polarization for analyzing binding of ruthenium metalloglycocluster to lectin and tetanus toxin C-fragment.","19537755",40]
["Glucose","Glucose","D005947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22575419","Investigation of the mechanism(s) involved in decreasing increased fibrinogen activity in hyperglycemic conditions using L-lysine supplementation.","22575419",40]
["Glucose","Glucose","D005947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26528809","A new strategy for achieving vertically-erected and hierarchical TiO2 nanosheets array/carbon cloth as a binder-free electrode for protein impregnation, direct electrochemistry and mediator-free glucose sensing.","26528809",40]
["Glucose","Glucose","D005947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"5473","Biological inactivation of proteins by the Maillard reaction. Effect of mild heat on the tertiary structure of insulin.","5473",40]
["Glucose","Glucose","D005947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7592791","Effect of the activation of phosphatidylinositol 3-kinase by a thiophosphotyrosine peptide on glucose transport in 3T3-L1 adipocytes.","7592791",40]
["Glucose","Glucose","D005947","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9746345","The transient association of ERp57 with N-glycosylated proteins is regulated by glucose trimming.","9746345",40]
["Glucose","Glucose","D005947","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1993,"8444168","The role of the Crabtree effect and an endogenous fuel in the energy metabolism of resting and proliferating thymocytes.","8444168",40]
["glucose-1-phosphate","glucose-1-phosphate","C031590","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"6791706","[Effect of glucose 1-phosphate and inorganic phosphate on binding of muscle phosphorylase b by glycogen].","6791706",40]
["Glutaral","Glutaral","D005976","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1986,"2943558","Glutaraldehyde dermatitis in nurses.","2943558",40]
["Glutaral","Glutaral","D005976","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1981,"6165755","Effects of glutaraldehyde and osmium tetroxide on newborn rat epidermal keratin.","6165755",40]
["Glyburide","Glyburide","D005905","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2004,"15102890","Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide.","15102890",40]
["Glycerol","Glycerol","D005990","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26463371","PpNrg1 is a transcriptional repressor for glucose and glycerol repression of AOX1 promoter in methylotrophic yeast Pichia pastoris.","26463371",40]
["Glycerol","Glycerol","D005990","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2001,"11382841","The ability of electrical measurements to predict skin moisturization. II. Correlation between one-hour measurements and long-term results.","11382841",40]
["glyceryl monothioglycolate","glyceryl monothioglycolate","C033769","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1984,"6234334","Permanent wave contact dermatitis: contact allergy to glyceryl monothioglycolate.","6234334",40]
["glycidamide","glycidamide","C071834","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15729833","Determination of haemoglobin adducts of acrylamide and glycidamide in smoking and non-smoking persons of the general population.","15729833",40]
["Glycogen","Glycogen","D006003","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15541350","Glycogen and related polysaccharides inhibit the laforin dual-specificity protein phosphatase.","15541350",40]
["glycolic acid","glycolic acid","C031149","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2002,"12213282","Inhibitory effect of glycolic acid on ultraviolet B-induced c-fos expression, AP-1 activation and p53-p21 response in a human keratinocyte cell line.","12213282",40]
["glycolic acid","glycolic acid","C031149","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"28330776","Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin.","28330776",40]
["Glycyrrhizic Acid","Glycyrrhizic Acid","D019695","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2005,"16207198","Vesicular drug eruption due to stronger Neo-Minophagen C.","16207198",40]
["Glyoxal","Glyoxal","D006037","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"10703647","Occupational allergic contact dermatitis from glyoxal, glutaraldehyde and neomycin sulfate in a dental nurse.","10703647",40]
["Gold Sodium Thiomalate","Gold Sodium Thiomalate","D006052","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1994,"7701895","Scarring alopecia following gold therapy.","7701895",40]
["Gold Sodium Thiomalate","Gold Sodium Thiomalate","D006052","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1994,"7799337","In vivo analysis of disease modifying drug therapy activity in rheumatoid arthritis by sequential immunohistological analysis of synovial membrane interleukin 1 beta.","7799337",40]
["Gold Sodium Thiosulfate","Gold Sodium Thiosulfate","D012971","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1995,"7774184","Contact allergy to gold sodium thiosulfate.","7774184",40]
["Granisetron","Granisetron","D017829","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2008,"18503688","Cutaneous adverse drug reactions during chemotherapy: consider non-antineoplastic drugs.","18503688",40]
["Grape Seed Proanthocyanidins","Grape Seed Proanthocyanidins","C511402","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"24798688","Grape seed proanthocyanidins inhibit cigarette smoke condensate-induced lung cancer cell migration through inhibition of NADPH oxidase and reduction in the binding of p22(phox) and p47(phox) proteins.","24798688",40]
["GSQ1530","GSQ1530","C471220","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12234840","In vitro antimicrobial activity of GSQ1530, a new heteroaromatic polycyclic compound.","12234840",40]
["Guanidine","Guanidine","D019791","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1964,"14124331","PHYSICAL AND IMMUNOLOGICAL PROPERTIES OF A SOLUBLE PRECURSOR OF THE POLIOVIRUS CAPSID.","14124331",40]
["Guanidine","Guanidine","D019791","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23984347","Spectroscopic studies on unfolding processes of apo-neuroglobin induced by guanidine hydrochloride and urea.","23984347",40]
["Guanine","Guanine","D006147","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15100216","A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme.NAD.inhibitor ternary complex.","15100216",40]
["Guanine","Guanine","D006147","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21602268","Adenine and guanine recognition of stop codon is mediated by different N domain conformations of translation termination factor eRF1.","21602268",40]
["guizhi-fuling","guizhi-fuling","C525079","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"26677713","[Research on immune-modulation effects and its mechanisms of Guizhi Fuling capsule and its active ingredient combination].","26677713",40]
["gusperimus","gusperimus","C037258","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1999,"10092197","Immunosuppressant deoxyspergualin-induced inhibition of cell proliferation is accompanied with an enhanced reduction of tetrazolium salt.","10092197",40]
["Gutta-Percha","Gutta-Percha","D006171","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1986,"3465705","[Methodology of a standard technic for evaluating bone biocompatibility of canal filling materials: II. Histologic results on 2 materials: gutta percha and zinc oxide eugenol].","3465705",40]
["H-2K(K) antigen","H-2K(K) antigen","C024755","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10520183","High peptide affinity for MHC class I does not correlate with immunodominance.","10520183",40]
["H-2K(K) antigen","H-2K(K) antigen","C024755","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1994,"8287623","Tumorigenicity of mouse T lymphoma cells is controlled by the level of major histocompatibility complex class I H-2Kk antigens.","8287623",40]
["Haloperidol","Haloperidol","D006220","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28188803","Activation of the sigma-1 receptor by haloperidol metabolites facilitates brain-derived neurotrophic factor secretion from human astroglia.","28188803",40]
["Halothane","Halothane","D006221","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1978,"81359","Sensitisation to halothane-altered liver components in severe hepatic necrosis after halothane anaesthesia.","81359",40]
["Halothane","Halothane","D006221","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1998510","Halothane metabolism: Kupffer cells carry and partially process trifluoroacetylated protein adducts.","1998510",40]
["hederacoside C","hederacoside C","C482302","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23607546","Pharmacokinetics of hederacoside C, an active ingredient in AG NPP709, in rats.","23607546",40]
["Hematoporphyrin Derivative","Hematoporphyrin Derivative","D017324","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1993,"8459315","Photodynamic effects on the nuclear envelope of human skin fibroblasts.","8459315",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"1247524","Influence of globin structures on the state of the heme. Ferrous low spin derivatives.","1247524",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12925227","Heme-scavenging role of alpha1-microglobulin in chronic ulcers.","12925227",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15326178","The C-helix in CooA rolls upon CO binding to ferrous heme.","15326178",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17582500","Interaction of iron(II)-heme and artemisinin with a peptide mimic of Plasmodium falciparum HRP-II.","17582500",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18278872","Dioxygen reactivity and heme redox potential of truncated human cystathionine beta-synthase.","18278872",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20947510","Perturbed heme binding is responsible for the blistering phenotype associated with mutations in the Caenorhabditis elegans dual oxidase 1 (DUOX1) peroxidase domain.","20947510",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23135388","Heme orientation modulates histidine dissociation and ligand binding kinetics in the hexacoordinated human neuroglobin.","23135388",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24000823","The species and heme pocket properties of sturgeon hemoglobins upon interaction with N-dodecyl trimethylammonium bromide.","24000823",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2557389","Preparation and spectral characterization of the heme d1.apomyoglobin complex: an unusual protein environment for the substrate-binding heme of Pseudomonas cytochrome oxidase.","2557389",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26874053","Internal switches modulating electron tunneling currents in respiratory complex III.","26874053",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1969,"4311823","The haem--protein interaction in cytochrome P-450.","4311823",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4710757","Heme formation from Fe(II) and porphyrin in the absence of ferrochelatase activity.","4710757",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"6243646","Electrostatic interactions in cytochrome c. The role of interactions between residues 13 and 90 and residues 79 and 47 in stabilizing the heme crevice structure.","6243646",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8458333","Evidence for an interaction between the CYP1(HAP1) activator and a cellular factor during heme-dependent transcriptional regulation in the yeast Saccharomyces cerevisiae.","8458333",40]
["Heme","Heme","D006418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9718296","Interaction site for soluble cytochromes on the tetraheme cytochrome subunit bound to the bacterial photosynthetic reaction center mapped by site-directed mutagenesis.","9718296",40]
["Hemin","Hemin","D006427","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20923763","Hemin binds to human cytoplasmic arginyl-tRNA synthetase and inhibits its catalytic activity.","20923763",40]
["Hemin","Hemin","D006427","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7998961","Multiple effects of haemin binding on protease susceptibility of bovine serum albumin and a novel isolation procedure for its large fragment.","7998961",40]
["Heparin","Heparin","D006493","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1994,"7911328","Anti-HIV-1 activity of chemically modified heparins: correlation between binding to the V3 loop of gp120 and inhibition of cellular HIV-1 infection in vitro.","7911328",40]
["Heparin","Heparin","D006493","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2004,"15274739","Intolerance of fondaparinux in a patient allergic to heparins.","15274739",40]
["Heparin","Heparin","D006493","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2017,"27941022","Basic Residues of β-Sheet A Contribute to Heparin Binding and Activation of Vaspin (Serpin A12).","27941022",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10512636","Vascular endothelial growth factor VEGF-like heparin-binding protein from the venom of Vipera aspis aspis (Aspic viper).","10512636",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"11067924","Characterization of the heparin-binding properties of IL-6.","11067924",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12553878","The heparin-binding 10 kDa fragment of connective tissue growth factor (CTGF) containing module 4 alone stimulates cell adhesion.","12553878",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1442259","Role of protein conformational changes, surface approximation and protein cofactors in heparin-accelerated antithrombin-proteinase reactions.","1442259",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15304392","Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia.","15304392",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16796563","Conformational transitions induced in heparin octasaccharides by binding with antithrombin III.","16796563",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18260648","Characterization of heparin oligosaccharides binding specifically to antithrombin III using mass spectrometry.","18260648",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20711880","Effect of the C-terminal domain peptide fragment (65-76) of monocytic chemotactic protein-1 (MCP-1) on the interaction between MCP-1 and heparin.","20711880",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21939260","Biophysical investigations on the interaction of the major bovine seminal plasma protein, PDC-109, with heparin.","21939260",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23338621","Recombinant hemangiopoietin promotes cell adhesion and binds heparin             in its multimeric form.","23338621",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25960020","Heparin enhances uptake of platelet factor 4/heparin complexes by monocytes and macrophages.","25960020",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2017,"27778131","The role of heparins and nano-heparins as therapeutic tool in breast cancer.","27778131",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"3997865","Heparin binding is necessary, but not sufficient, for fibronectin aggregation. A fluorescence polarization study.","3997865",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1979,"486155","On the molecular-weight-dependence of the anticoagulant activity of heparin.","486155",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7287751","Binding of high affinity heparin to antithrombin III. Characterization of the protein fluorescence enhancement.","7287751",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1995,"7487882","Identification of a heparin-binding protein using monoclonal antibodies that block heparin binding to porcine aortic endothelial cells.","7487882",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7911328","Anti-HIV-1 activity of chemically modified heparins: correlation between binding to the V3 loop of gp120 and inhibition of cellular HIV-1 infection in vitro.","7911328",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9325317","Heparin/heparan sulfate (HP/HS) interacting protein (HIP) supports cell attachment and selective, high affinity binding of HP/HS.","9325317",40]
["Heparin","Heparin","D006493","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9808060","Human endothelial cells do not exert heparin like accelerating effects on thrombin-antithrombin-complex formation.","9808060",40]
["Heparin","Heparin","D006493","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1993,"8241974","Low-dose heparin inhibits acute graft versus host disease in mice.","8241974",40]
["Heparin, Low-Molecular-Weight","Heparin, Low-Molecular-Weight","D006495","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2016,"25853237","Low-Molecular-Weight Heparins as Immunomodulators in Dermatology Practice.","25853237",40]
["Heparin, Low-Molecular-Weight","Heparin, Low-Molecular-Weight","D006495","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23245333","An apoptosis-homing peptide-conjugated low molecular weight heparin-taurocholate conjugate with antitumor properties.","23245333",40]
["Heparitin Sulfate","Heparitin Sulfate","D006497","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10708453","Vaccinia virus envelope H3L protein binds to cell surface heparan sulfate and is important for intracellular mature virion morphogenesis and virus infection in vitro and in vivo.","10708453",40]
["Heparitin Sulfate","Heparitin Sulfate","D006497","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12374790","Location of N-unsubstituted glucosamine residues in heparan sulfate.","12374790",40]
["Heparitin Sulfate","Heparitin Sulfate","D006497","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18715996","Heparan sulfate regulates ephrin-A3/EphA receptor signaling.","18715996",40]
["Heparitin Sulfate","Heparitin Sulfate","D006497","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20889969","Cobra CRISP functions as an inflammatory modulator via a novel Zn2+- and heparan sulfate-dependent transcriptional regulation of endothelial cell adhesion molecules.","20889969",40]
["Heparitin Sulfate","Heparitin Sulfate","D006497","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23571092","Mutation of the dengue virus type 2 envelope protein heparan sulfate binding sites or the domain III lateral ridge blocks replication in Vero cells prior to membrane fusion.","23571092",40]
["Heparitin Sulfate","Heparitin Sulfate","D006497","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8729007","Importance of specific amino acids in protein binding sites for heparin and heparan sulfate.","8729007",40]
["Heparitin Sulfate","Heparitin Sulfate","D006497","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9737951","Regulated diversity of heparan sulfate.","9737951",40]
["Heroin","Heroin","D003932","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1998,"9694946","Alterations of immune functions in heroin addicts and heroin withdrawal subjects.","9694946",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C70403,B70403)","v":"Hesperidin"},"Hesperidin","D006569","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J70403,K70403)","v":"CD4-Positive T-Lymphocytes"},"D015496","CD4-Positive T-Lymphocytes",1,1,2014,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q70403,Q70403)","v":"24891765"},"Hesperidin inhibits inflammatory response induced by Aeromonas hydrophila infection and alters CD4+/CD8+ T cell ratio.","24891765",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C70467,B70467)","v":"Hexachlorophene"},"Hexachlorophene","D006582","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J70467,K70467)","v":"Dermatitis, Allergic Contact"},"D017449","Dermatitis, Allergic Contact",0,2,1995,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q70467,Q70467)","v":"7593808"},"Allergy to Unna boots in four patients.","7593808",40]
["Hexobarbital","Hexobarbital","D006591","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1968,"4239201","[Influence of acidosis and alkalosis on the binding of drugs to plasma proteins].","4239201",40]
["hexylene glycol","hexylene glycol","C011480","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2529099","Skin reactions to hexylene glycol.","2529099",40]
["Histamine","Histamine","D006632","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1960,"14402485","Further observations on the disruption of rat mesentery mast cells caused by compound 48/80, antigen-antibody reaction, lecithinase A and decylamine.","14402485",40]
["Histamine","Histamine","D006632","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2003,"12847474","Histamine in the immune regulation of allergic inflammation.","12847474",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,-1,2013,"23966004","Feline non-flea induced hypersensitivity dermatitis: clinical features, diagnosis and treatment.","23966004",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1964,"14225128","INFANTILE ECZEMA, ASTHMA AND HAY FEVER IN MONGOLISM.","14225128",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2013,"24028473","Analysis of comorbidities and therapeutic approach for allergic rhinitis in a pediatric population in Spain.","24028473",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,-1,2010,"20956103","Facial eruption related to snorting Ecstasy.","20956103",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1967,"4232420","Studies on the mechanisms of delayed type hypersensitivity in tissue cultures. 8. Influence of some pharmacologically active substances on the migration activity of spleen cells and the result of delayed (cellular) type hypersensitivity in vitro.","4232420",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,2016,"27362402","Comparison of different local and imported histamine concentrations used as a skin prick test positive control.","27362402",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1974,"4367153","[Histamine sensitization induced with Bordetella pertussis and other microbial agents].","4367153",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1984,"6235759","The regulatory effect of histamine on the immune response: III. Defect on in vitro IgE production in atopics.","6235759",40]
["Histamine","Histamine","D006632","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2014,"25219105","Histamine exerts multiple effects on expression of genes associated with epidermal barrier function.","25219105",40]
["Histamine","Histamine","D006632","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21749919","The hydrophobic amino acids in putative helix 8 in carboxy-terminus of histamine H(3) receptor are involved in receptor-G-protein coupling.","21749919",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2002,"12140471","Sensitivity of human scalp skin to pruritic stimuli investigated by intradermal microdialysis in vivo.","12140471",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2004,"15500482","Determination of threshold concentrations of allergens and evaluation of two different histamine concentrations in canine intradermal testing.","15500482",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1990,"2201685","The histamine degradative uptake pathway in human vascular endothelial cells and skin fibroblasts is dependent on extracellular Na+ and Cl-.","2201685",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1982,"6291570","Adrenoceptor-agonist inhibition of the histamine-induced cutaneous response in man.","6291570",40]
["Histamine","Histamine","D006632","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9552753","Duodenal ulcer patients exhibit a greater skin response to histamine.","9552753",40]
["Histamine","Histamine","D006632","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6460188","Abnormal histamine-induced suppressor-cell function in atopic subjects.","6460188",40]
["histapyrrodine","histapyrrodine","C049920","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,1954,"13191099","[Clinical experiences with calcistin].","13191099",40]
["Histocompatibility Antigen H-2D","Histocompatibility Antigen H-2D","D064532","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9086276","Traffic control of completely assembled MHC class I molecules beyond the endoplasmic reticulum.","9086276",40]
["histrionicotoxin","histrionicotoxin","C007948","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8049208","The histrionicotoxin-sensitive ethidium binding site is located outside of the transmembrane domain of the nicotinic acetylcholine receptor: a fluorescence study.","8049208",40]
["homoisocitric acid","homoisocitric acid","C517550","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27601325","Determinants of dual substrate specificity revealed by the crystal structure of homoisocitrate dehydrogenase from Thermus thermophilus in complex with homoisocitrate·Mg(2+)·NADH.","27601325",40]
["huprine Y","huprine Y","C404519","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"22236498","Expanding the multipotent profile of huprine-tacrine heterodimers as disease-modifying anti-Alzheimer agents.","22236498",40]
["H-Y Antigen","H-Y Antigen","D006182","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2008,"18812197","Human CD8+ T-regulatory cells with low-avidity T-cell receptor specific for minor histocompatibility antigens.","18812197",40]
["Hyaluronic Acid","Hyaluronic Acid","D006820","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1996,"8636151","A blood group-related polymorphism of CD44 abolishes a hyaluronan-binding consensus sequence without preventing hyaluronan binding.","8636151",40]
["Hyaluronic Acid","Hyaluronic Acid","D006820","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2016,"27869206","Endotoxin free hyaluronan and hyaluronan fragments do not stimulate TNF-α, interleukin-12 or upregulate co-stimulatory molecules in dendritic cells or macrophages.","27869206",40]
["Hyaluronic Acid","Hyaluronic Acid","D006820","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,2005,"15864059","Native hyaluronan produces less hypersensitivity than cross-linked hyaluronan.","15864059",40]
["Hyaluronic Acid","Hyaluronic Acid","D006820","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2017,"28259681","Stem Cell-Containing Hyaluronic Acid-Based Spongy Hydrogels for Integrated Diabetic Wound Healing.","28259681",40]
["Hyaluronic Acid","Hyaluronic Acid","D006820","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11464867","Role of CD44H carbohydrate structure in neuroblastoma adhesive properties.","11464867",40]
["Hyaluronic Acid","Hyaluronic Acid","D006820","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22444322","The influence of glycosaminoglycans on IL-8-mediated functions of neutrophils.","22444322",40]
["Hyaluronic Acid","Hyaluronic Acid","D006820","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25937513","CD44S-hyaluronan interactions protect cells resulting from EMT against anoikis.","25937513",40]
["Hyaluronic Acid","Hyaluronic Acid","D006820","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4277351","Aggregation of cartilage proteoglycans. I. The role of hyaluronic acid.","4277351",40]
["Hyaluronic Acid","Hyaluronic Acid","D006820","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21412035","Fifty-kDa hyaluronic acid upregulates some epidermal genes without changing TNF-α expression in reconstituted epidermis.","21412035",40]
["Hyaluronic Acid","Hyaluronic Acid","D006820","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"25775637","Skin Necrosis from Intra-articular Hyaluronic Acid Injection.","25775637",40]
["Hydralazine","Hydralazine","D006830","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1995,"8547013","Drug-induced Sweet's syndrome (acute febrile neutrophilic dermatosis) associated with hydralazine.","8547013",40]
["hydrazine","hydrazine","C029424","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21905743","Hydrazide reactive peptide tags for site-specific protein labeling.","21905743",40]
["Hydrogel, Polyethylene Glycol Dimethacrylate","Hydrogel, Polyethylene Glycol Dimethacrylate","D020136","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2009,"20187087","The morphological and biomechanical changes of keratocytes cultured on modified p (HEMA-MMA) hydrogel studied by AFM.","20187087",40]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,1998,"9433911","Suppression of intracellular hydrogen peroxide generation and catalase levels in CD8+ T-lymphocytes from HIV+ individuals.","9433911",40]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2001,"11182298","Vitamin E analog modulates UVB-induced signaling pathway activation and enhances cell survival.","11182298",40]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"136969","Oxidative titrations of Rhus vernicifera laccase and its specific interaction with hydrogen peroxide.","136969",40]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17592724","Hydrogen peroxide-mediated oxidative stress disrupts calcium binding on calmodulin: more evidence for oxidative stress in vitiligo.","17592724",40]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2017,"27913425","CD36 mediates H2O2-induced calcium influx in lung microvascular endothelial cells.","27913425",40]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9585534","Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide.","9585534",40]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2911585","Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.","2911585",40]
["Hydrogen Sulfide","Hydrogen Sulfide","D006862","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25537304","Reactivity of inorganic sulfide species toward a heme protein model.","25537304",40]
["hydroquinone","hydroquinone","C031927","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20034485","Topoisomerase II inhibition by the bioactivated benzene metabolite hydroquinone involves multiple mechanisms.","20034485",40]
["Hydroxychloroquine","Hydroxychloroquine","D006886","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"24121037","Cellular and urinary microRNA alterations in NZB/W mice with hydroxychloroquine or prednisone treatment.","24121037",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C73923,B73923)","v":"hydroxyethyl methacrylate"},"hydroxyethyl methacrylate","C005044","2_KE",826,2,"Keratinocytes","Activation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J73923,K73923)","v":"Keratinocytes"},"D015603","Keratinocytes",1,3,2008,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q73923,Q73923)","v":"18793918"},"Mechanisms of N-acetyl cysteine-mediated protection from 2-hydroxyethyl methacrylate-induced apoptosis.","18793918",40]
["Hydroxyindoleacetic Acid","Hydroxyindoleacetic Acid","D006897","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2475644","Indole amine deficiency in blood and cerebrospinal fluid from patients with human immunodeficiency virus infection.","2475644",40]
["hydroxypropyl guar","hydroxypropyl guar","C519976","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16229524","Hydroxypropyl guar-borate interactions with tear film mucin and lysozyme.","16229524",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C74115,B74115)","v":"Hydroxyurea"},"Hydroxyurea","D006918","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J74115,K74115)","v":"CD4-Positive T-Lymphocytes"},"D015496","CD4-Positive T-Lymphocytes",1,3,2016,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q74115,Q74115)","v":"27620852"},"Barriers to HIV Cure.","27620852",40]
["Hydroxyzine","Hydroxyzine","D006919","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,2,1990,"1973069","Does reversed-type anaphylaxis in healthy subjects mimic a real allergic reaction?","1973069",40]
["Hydroxyzine","Hydroxyzine","D006919","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1683840","Pharmacological modulation by cetirizine and ebastine of the cutaneous reactivity to histamine.","1683840",40]
["Hymecromone","Hymecromone","D006923","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6687990","Manganese, calcium, and saccharide binding to concanavalin A, as studied by ultrafiltration.","6687990",40]
["Hypochlorous Acid","Hypochlorous Acid","D006997","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9916287","Which conditions promote a remanent (persistent) bactericidal activity of chlorine covers?","9916287",40]
["ibandronic acid","ibandronic acid","C073007","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2012,"21225298","The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes--in vitro study.","21225298",40]
["Ibuprofen","Ibuprofen","D007052","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"28009827","Synthesis, Bioevaluation and Molecular Dynamic Simulation Studies of Dexibuprofen-Antioxidant Mutual Prodrugs.","28009827",40]
["Ibuprofen","Ibuprofen","D007052","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2003,"14559395","Post-iontophoresis transport of ibuprofen lysine across rabbit ear skin.","14559395",40]
["ibuproxam","ibuproxam","C025377","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1987,"2957156","Contact dermatitis to ibuproxam.","2957156",40]
["Idazoxan","Idazoxan","D019329","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12919003","Identification and characterization of the imidazoline I2b-binding sites in the hamster brown adipose tissue as a study model for imidazoline receptors.","12919003",40]
["ifenprodil","ifenprodil","C010739","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22743575","Structural changes of regulatory domain heterodimer of N-methyl-D-aspartate receptor subunits GluN1 and GluN2B through the binding of spermine and ifenprodil.","22743575",40]
["Imatinib Mesylate","Imatinib Mesylate","D000068877","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2003,"12582389","Adverse cutaneous reactions to imatinib (STI571) in Philadelphia chromosome-positive leukemias: a prospective study of 54 patients.","12582389",40]
["Imatinib Mesylate","Imatinib Mesylate","D000068877","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10815921","The tyrosine kinase inhibitor CGP 57148 (ST1 571) induces apoptosis in BCR-ABL-positive cells by down-regulating BCL-X.","10815921",40]
["Imatinib Mesylate","Imatinib Mesylate","D000068877","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16840200","Intermittent dosage of imatinib mesylate in CML patients with a history of significant hematologic toxicity after standard dosing.","16840200",40]
["imidacloprid","imidacloprid","C082359","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20005950","Native subunit composition of two insect nicotinic receptor subtypes with differing affinities for the insecticide imidacloprid.","20005950",40]
["imidazole","imidazole","C029899","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"17002288","Structural, kinetic, and thermodynamic analysis of glucoimidazole-derived glycosidase inhibitors.","17002288",40]
["Imipramine","Imipramine","D007099","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1979,"112637","Binding of imipramine to plasma protein and to brain tissue: relationship to CSF tricyclic levels in man.","112637",40]
["Imipramine","Imipramine","D007099","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4412708","Deamination of beta-phenylethylamine by monoamine oxidase--inhibition by imipramine.","4412708",40]
["imiquimod","imiquimod","C056493","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1999,"10597781","A randomized, controlled, safety study using imiquimod for the topical treatment of anogenital warts in HIV-infected patients. Imiquimod Study Group.","10597781",40]
["imiquimod","imiquimod","C056493","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2013,"23407395","IL-1R1 signaling facilitates Munro's microabscess formation in psoriasiform imiquimod-induced skin inflammation.","23407395",40]
["imiquimod","imiquimod","C056493","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2009,"18596825","Imiquimod, a Toll-like receptor 7 agonist, inhibits melanogenesis and proliferation of human melanocytes.","18596825",40]
["INCB018424","INCB018424","C540383","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21677670","Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammation.","21677670",40]
["indanocine","indanocine","C404326","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2000,"10655426","Tubulin/microtubules: still a promising target for new chemotherapeutic agents.","10655426",40]
["indirubin-3'-monoxime","indirubin-3'-monoxime","C474021","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"21948866","Dietary ligands of the aryl hydrocarbon receptor induce anti-inflammatory and immunoregulatory effects on murine dendritic cells.","21948866",40]
["Indocyanine Green","Indocyanine Green","D007208","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9252530","Nontraditional effects of protein binding and hematocrit on uptake of indocyanine green by perfused rat liver.","9252530",40]
["indol-3-yl pyruvic acid","indol-3-yl pyruvic acid","C008122","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3548822","Stereochemistry and mechanism of a new single-turnover, half-transamination reaction catalyzed by the tryptophan synthase alpha 2 beta 2 complex.","3548822",40]
["Indomethacin","Indomethacin","D007213","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,1991,"1906386","A role for prostaglandins in the suppression of cutaneous cellular immunity and tumour development in benzo(a)pyrene- but not dimethylbenz(a)anthracene-treated mice.","1906386",40]
["Indomethacin","Indomethacin","D007213","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12813129","Reduction of beta-catenin/T-cell transcription factor signaling by aspirin and indomethacin is caused by an increased stabilization of phosphorylated beta-catenin.","12813129",40]
["Indomethacin","Indomethacin","D007213","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1978,"728148","Indomethacin inhibition of cell proliferation induced by the phorbolester TPA is reversed by prostaglandin E2 in mouse epidermis in vivo.","728148",40]
["Indomethacin","Indomethacin","D007213","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1983,"6408901","Improvement of abnormal lymphocyte responses in \"atypical\" mycobacteriosis with indomethacin.","6408901",40]
["Industrial Waste","Industrial Waste","D007220","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"24395402","Evaluation of electric arc furnace-processed steel slag for dermal corrosion, irritation, and sensitization from dermal contact.","24395402",40]
["Inositol","Inositol","D007294","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7845353","Molecular and genetic characterization of the rhizopine catabolism (mocABRC) genes of Rhizobium meliloti L5-30.","7845353",40]
["Inositol 1,4,5-Trisphosphate","Inositol 1,4,5-Trisphosphate","D015544","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12123706","Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in vitro.","12123706",40]
["Inositol 1,4,5-Trisphosphate","Inositol 1,4,5-Trisphosphate","D015544","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1993,"8468465","Modulation of the intracellular Ca2+ and inositol trisphosphate concentrations in murine T lymphocytes by the glycosylphosphatidylinositol-anchored protein sgp-60.","8468465",40]
["Inulin","Inulin","D007444","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2013,"23506468","Development of soluble inulin microparticles as a potent and safe vaccine adjuvant and delivery system.","23506468",40]
["Iodipamide","Iodipamide","D007458","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1978,"698028","Iotroxamide studies in man--plasma binding, renal and biliary excretion studies in jaundiced and anicteric patients.","698028",40]
["Iodoquinol","Iodoquinol","D004103","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1975,"122845","Letter: Diiodohydroxyquin warning.","122845",40]
["Ionomycin","Ionomycin","D015759","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2001,"11476900","Effect of phorbol ester and calcium ionophore on human thymocytes.","11476900",40]
["Iopanoic Acid","Iopanoic Acid","D007480","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1979,"113366","Pharmacokinetics of iopanoic acid in the rhesus monkey: biliary excretion, plasma protein binding and biotransformation.","113366",40]
["iotrolan","iotrolan","C033300","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1991,"1838559","Late phase allergic reaction to a CT contrast medium (iotrolan).","1838559",40]
["irbesartan","irbesartan","C081309","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2006,"16677251","Lichenoid drug eruption due to an antihypertonic drug containing irbesartan and hydrochlorothiazide.","16677251",40]
["Isatin","Isatin","D007510","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23416001","Spirocyclic replacements for the isatin in the highly selective, muscarinic M1 PAM ML137: the continued optimization of an MLPCN probe molecule.","23416001",40]
["isoalantolactone","isoalantolactone","C032787","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1982,"7165323","Allergic contact dermatitis to methylenelactones. Use of lymphocyte transformation test.","7165323",40]
["Isoflurophate","Isoflurophate","D007531","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18344198","In vitro oxime protection of human red blood cell acetylcholinesterase inhibited by diisopropyl-fluorophosphate.","18344198",40]
["isoglobotrihexosylceramide","isoglobotrihexosylceramide","C514781","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18295796","Crystal structures of mouse CD1d-iGb3 complex and its cognate Valpha14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids.","18295796",40]
["Isoniazid","Isoniazid","D007538","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1979,"288324","Studies on the role of acetylhydrazine in isoniazid hepatotoxicity.","288324",40]
["Isoniazid","Isoniazid","D007538","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1979,"311522","The effect of oral isoniazid on human lymphocyte subpopulations.","311522",40]
["isopentenyl pyrophosphate","isopentenyl pyrophosphate","C004809","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2009,"19710470","Specific requirements for Vgamma9Vdelta2 T cell stimulation by a natural adenylated phosphoantigen.","19710470",40]
["Isoproterenol","Isoproterenol","D007545","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1976,"188460","Effects of choleragen on hormonal responsiveness of adenylate cyclase in human fibroblasts and rat fat cells.","188460",40]
["Isoproterenol","Isoproterenol","D007545","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1979,"315401","Effect of catecholamines on lymphopoiesis in fetal mouse thymic explants.","315401",40]
["Isotretinoin","Isotretinoin","D015474","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2005,"16185265","Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin.","16185265",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C77635,B77635)","v":"Isotretinoin"},"Isotretinoin","D015474","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J77635,K77635)","v":"Skin"},"D012867","Skin",0,1,2016,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q77635,Q77635)","v":"26845242"},"Isotretinoin treatment reduces acne lesions but not directly lesional acne inflammation.","26845242",40]
["isoxicam","isoxicam","C013580","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3447908","Comparative biochemical pharmacology of the oxicams.","3447908",40]
["Ivermectin","Ivermectin","D007559","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2005,"16409259","Ivermectin: pharmacology and application in dermatology.","16409259",40]
["jadomycin B","jadomycin B","C081750","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15817470","Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase.","15817470",40]
["JM 3100","JM 3100","C088327","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21210239","CXCL12/CXCR4 signaling in malignant brain tumors: a potential pharmacological therapeutic target.","21210239",40]
["JP5 jet fuel","JP5 jet fuel","C029662","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"17890764","Dermal exposure to jet fuel suppresses delayed-type hypersensitivity: a critical role for aromatic hydrocarbons.","17890764",40]
["kaempferol","kaempferol","C006552","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12565887","Flavonoid glycoside: a new inhibitor of eukaryotic DNA polymerase alpha and a new carrier for inhibitor-affinity chromatography.","12565887",40]
["kaitocephalin","kaitocephalin","C442421","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"23076153","The structure of (-)-kaitocephalin bound to the ligand binding domain of the (S)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/glutamate receptor, GluA2.","23076153",40]
["Kanamycin","Kanamycin","D007612","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1969,"5793757","The relationship between kanamycin pharmacokinetics: distribution and renal function.","5793757",40]
["KBF 611","KBF 611","C545905","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20038272","Preclinical pharmacokinetics of KBF611, a new antituberculosis agent in mice and rabbits, and comparison with thiacetazone.","20038272",40]
["Keratan Sulfate","Keratan Sulfate","D007632","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19008226","Homologous sequence in lumican and fibromodulin leucine-rich repeat 5-7 competes for collagen binding.","19008226",40]
["Ketoconazole","Ketoconazole","D007654","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1992,"1451511","Contact dermatitis from ketoconazole cream.","1451511",40]
["Ketoconazole","Ketoconazole","D007654","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1989,"2533540","Hypersensitivity to ketoconazole preparations: study of 4 cases.","2533540",40]
["Ketoprofen","Ketoprofen","D007660","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2009,"19157794","Skin application of ketoprofen systemically suppresses contact hypersensitivity by inducing CD4(+) CD25(+) regulatory T cells.","19157794",40]
["ketoprofen glucuronide","ketoprofen glucuronide","C044223","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24361714","Predicted multiple selected reaction monitoring to screen activated drug-mediated modifications on human serum albumin.","24361714",40]
["Ketotifen","Ketotifen","D007665","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2003,"14519926","Enhanced skin permeation of cationic drug ketotifen through excised guinea pig dorsal skin by surfactants with different electric charges.","14519926",40]
["KP 1339","KP 1339","C551585","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21935553","LC- and CZE-ICP-MS approaches for the in vivo analysis of the anticancer drug candidate sodium trans-[tetrachloridobis(1H-indazole)ruthenate(III)] (KP1339) in mouse plasma.","21935553",40]
["K-strophanthoside","K-strophanthoside","C008240","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1958,"13619655","Depolarizing action of K-strophantine and K-strophanthoside on isolated frog skin.","13619655",40]
["kyung-ok-ko","kyung-ok-ko","C000592339","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2016,"26899592","Effects of Oriental Medicine Kyung-Ok-Ko on Uterine Abnormality in Hyperandrogenized Rats.","26899592",40]
["Lactic Acid","Lactic Acid","D019344","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2006,"16288857","Preparation of protein loaded poly(D,L-lactide-co-glycolide) microparticles for the antigen delivery to dendritic cells using a static micromixer.","16288857",40]
["Lactic Acid","Lactic Acid","D019344","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2015,"25465442","CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses.","25465442",40]
["Lactic Acid","Lactic Acid","D019344","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,1,2009,"19797889","Late-onset immune-mediated adverse effects after poly-L-lactic acid injection in non-HIV patients: clinical findings and long-term follow-up.","19797889",40]
["Lactic Acid","Lactic Acid","D019344","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16848011","Point:Counterpoint authors respond to commentaries on \"Lactic acid accumulation is an advantage/disadvantage during muscle activity\".","16848011",40]
["Lactic Acid","Lactic Acid","D019344","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10417580","Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy.","10417580",40]
["lacto-N-fucopentaose III","lacto-N-fucopentaose III","C434666","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"16689863","Prevention of psoriasis-like lesions development in fsn/fsn mice by helminth glycans.","16689863",40]
["Lactose","Lactose","D007785","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12139934","High-resolution crystal structures of Erythrina cristagalli lectin in complex with lactose and 2'-alpha-L-fucosyllactose and correlation with thermodynamic binding data.","12139934",40]
["Lactulose","Lactulose","D007792","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2015,"26272706","Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics.","26272706",40]
["laminarin sulfate","laminarin sulfate","C053460","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"8579728","Differential effects of polysulfated polysaccharide on experimental encephalomyelitis, proliferation of autoimmune T cells, and inhibition of heparanase activity.","8579728",40]
["lamotrigine","lamotrigine","C047781","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1997,"9247416","Lamotrigine treatment of rapid cycling bipolar disorder.","9247416",40]
["lapatinib","lapatinib","C490728","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2008,"18313293","Neutral 5-substituted 4-indazolylaminoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase.","18313293",40]
["latanoprost","latanoprost","C072042","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2002,"11887105","Allergic contact dermatitis to latanoprost.","11887105",40]
["Latex","Latex","D007840","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1998,"9599345","Latex allergy awareness.","9599345",40]
["Latex","Latex","D007840","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1994,"10137371","Disease prevention means reduced spending.","10137371",40]
["Latex","Latex","D007840","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1994,"7984483","Hidden dilemma.","7984483",40]
["Latex","Latex","D007840","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,1995,"7573824","Is systematic preoperative screening for muscle relaxant and latex allergy advisable?","7573824",40]
["Latex","Latex","D007840","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,1996,"8828526","Allergy to latex in spina bifida: a multivariate study of associated factors in 100 consecutive patients.","8828526",40]
["latoconazole","latoconazole","C072774","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2015,"25675966","Anti-inflammatory activity of lanoconazole, a topical antifungal agent.","25675966",40]
["lauric acid","lauric acid","C030358","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27890614","Structural insights into the binding of lauric acid to CYP107L2 from Streptomyces avermitilis.","27890614",40]
["lawsone","lawsone","C005090","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"11115163","Allergic contact dermatitis caused by skin painting (pseudotattooing) with black henna, a mixture of henna and p-phenylenediamine and its derivatives.","11115163",40]
["lawsone","lawsone","C005090","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2002,"12492530","Fragrance sensitization caused by temporary henna tattoo.","12492530",40]
["LDS 751","LDS 751","C057718","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9652412","Transport of LDS-751 from the cytoplasmic leaflet of the plasma membrane by the rhodamine-123-selective site of P-glycoprotein.","9652412",40]
["leflunomide","leflunomide","C045463","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1998,"9640628","Effect of leflunomide and cyclosporine on graft survival and changes in lymphocyte phenotypes in a rat heart allotransplantation model.","9640628",40]
["lenalidomide","lenalidomide","C467567","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2017,"27889516","Lenalidomide enhances the function of dendritic cells generated from patients with multiple myeloma.","27889516",40]
["Lepromin","Lepromin","D007916","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1980,"6969506","[Lymphocyte sensitization to lepromin in patients with polar types of leprosy].","6969506",40]
["Leucovorin","Leucovorin","D002955","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1979,"313168","Immunoassay of leucovorin: use of 125I-labeled protein A to detect immunological binding.","313168",40]
["leukotoxin","leukotoxin","C018579","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23234758","Monodisperse and LPS-free Aggregatibacter actinomycetemcomitans leukotoxin: interactions with human β2 integrins and erythrocytes.","23234758",40]
["Leukotriene B4","Leukotriene B4","D007975","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2560652","Leukotriene B4 receptors on neutrophils in patients with psoriasis and atopic eczema.","2560652",40]
["Leukotriene B4","Leukotriene B4","D007975","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1992,"1336720","The inter-relation between inflammation and epidermal proliferation in normal skin following epicutaneous application of leukotriene-B4--an immunohistochemical study.","1336720",40]
["Levamisole","Levamisole","D007978","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,2,1986,"3767338","[Effect of papain and levamisole on the body's immunological indices and oxidation-reduction processes in experimental sensitization].","3767338",40]
["Levamisole","Levamisole","D007978","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,1981,"7193435","A child with atopic features, raised serum IgE, and recurrent infection treated with levamisole.","7193435",40]
["Levamisole","Levamisole","D007978","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1988,"3266914","Effect of levamisole on the course of experimental leishmaniasis in guinea-pigs and mice: haematological and immunological findings.","3266914",40]
["Levamisole","Levamisole","D007978","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1978,"356739","The use of levamisole in atopic dermatitis: a prospective study.","356739",40]
["Levamisole","Levamisole","D007978","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1980,"6966379","[Levamisole and rheumatoid arthritis].","6966379",40]
["levocetirizine","levocetirizine","C472067","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"18552044","[Does new antihistamines characterize tachyphylaxis phenomenon?].","18552044",40]
["Levonorgestrel","Levonorgestrel","D016912","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"6795390","Binding of the gestagens norethisterone and levonorgestrel in blood of various species.","6795390",40]
["Lewis X Antigen","Lewis X Antigen","D016256","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2005,"16239964","Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes.","16239964",40]
["Lewis X Antigen","Lewis X Antigen","D016256","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1996,"9398905","Helicobacter pylori expresses Lewis X.","9398905",40]
["LFA 878","LFA 878","C494439","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15304496","Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo.","15304496",40]
["Lidocaine","Lidocaine","D008012","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2013,"23278914","Serum lidocaine levels and cutaneous side effects after application of 23% lidocaine 7% tetracaine ointment to the face.","23278914",40]
["Lidocaine","Lidocaine","D008012","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,1995,"8906954","Lignocaine toxicity following pleurodesis.","8906954",40]
["Lidocaine","Lidocaine","D008012","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3411474","Differential effect of pentobarbital and chloralose in anesthetic doses on the serum protein binding of lidocaine in the dog.","3411474",40]
["Lidocaine","Lidocaine","D008012","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22812663","A pharmacokinetic study of a topical anesthetic (EMLA® ) in mouse soft tissue laceration.","22812663",40]
["Lidocaine","Lidocaine","D008012","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"8077605","In vitro effects of cocaine, lidocaine and monoamine uptake inhibitors on lymphocyte proliferative responses.","8077605",40]
["limonene","limonene","C008281","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,-1,2010,"20163165","Structural influence on radical formation and sensitizing capacity of alkylic limonene hydroperoxide analogues in allergic contact dermatitis.","20163165",40]
["Linagliptin","Linagliptin","D000069476","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2016,"26820308","Three Cases of Bullous Pemphigoid Associated with Dipeptidyl Peptidase-4 Inhibitors - One due to Linagliptin.","26820308",40]
["Linoleic Acid","Linoleic Acid","D019787","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18321850","Linoleic acid induces calcium signaling, Src kinase phosphorylation, and neurotransmitter release in mouse CD36-positive gustatory cells.","18321850",40]
["Linoleic Acid","Linoleic Acid","D019787","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1987,"2831674","[Clinical and immune-modulating effects of the treatment with unsaturated fatty acids in atopic dermatitis].","2831674",40]
["Lipid A","Lipid A","D008050","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2009,"19748578","Liposome-encapsulated HIV-1 Gag p24 containing lipid A induces effector CD4+ T-cells, memory CD8+ T-cells, and pro-inflammatory cytokines.","19748578",40]
["Lipid A","Lipid A","D008050","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16549045","The molecular mechanism of interaction between sushi peptide and Pseudomonas endotoxin.","16549045",40]
["Lipid A","Lipid A","D008050","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1994,"7980398","Binding of surfactant protein A to the lipid A moiety of bacterial lipopolysaccharides.","7980398",40]
["lipoamide","lipoamide","C013091","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11368334","Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates.","11368334",40]
["lipoarabinomannan","lipoarabinomannan","C050016","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19577573","Structural insights into antibody recognition of mycobacterial polysaccharides.","19577573",40]
["lipophosphonoglycan","lipophosphonoglycan","C008290","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2005,"15657947","A critical role for lipophosphoglycan in proinflammatory responses of dendritic cells to Leishmania mexicana.","15657947",40]
["lipoteichoic acid","lipoteichoic acid","C009900","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2017,"28764320","Lipoteichoic Acid Isolated from Staphylococcus aureus Induces Both Epithelial-Mesenchymal Transition and Wound Healing in HaCaT Cells.","28764320",40]
["lipoteichoic acid","lipoteichoic acid","C009900","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1992,"1486235","Thymocyte proliferation and maturation in response to staphylococcal lipoteichoic acid.","1486235",40]
["Lithium Chloride","Lithium Chloride","D018021","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"7945679","Modulation of cell-mediated immunity by lithium chloride.","7945679",40]
["Liver Glycogen","Liver Glycogen","D008112","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1971,"5003690","Immunological studies on glycogen storage diseases type 3 and V. Demonstration of the presence of an immunoreactive protein in one case of muscle phosphorylase deficiency.","5003690",40]
["locobase","locobase","C085972","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2002,"12190621","Effect of a lipid-rich emollient containing ceramide 3 in experimentally induced skin barrier dysfunction.","12190621",40]
["Lopinavir","Lopinavir","D061466","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2013,"23383047","Kinetics of microbial translocation markers in patients on efavirenz or lopinavir/r based antiretroviral therapy.","23383047",40]
["lopinavir-ritonavir drug combination","lopinavir-ritonavir drug combination","C558899","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2016,"26323809","Peripheral neuropathy in HIV patients in sub-Saharan Africa failing first-line therapy and the response to second-line ART in the EARNEST trial.","26323809",40]
["Lovastatin","Lovastatin","D008148","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"20526818","Immunomodulatory effects of IFN-beta and lovastatin on immunophenotype of monocyte-derived dendritic cells in multiple sclerosis.","20526818",40]
["Lovastatin","Lovastatin","D008148","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1980,"6965969","Sterol metabolism and lymphocyte function: inhibition of endogenous sterol biosynthesis does not prevent mitogen-induced human T lymphocyte activation.","6965969",40]
["Lutein","Lutein","D014975","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23720734","Mechanisms underlying carotenoid absorption in oxygenic photosynthetic proteins.","23720734",40]
["Luteolin","Luteolin","D047311","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26828287","Bovine serum albumin binding, antioxidant and anticancer properties of an oxidovanadium(IV) complex with luteolin.","26828287",40]
["LY 117018","LY 117018","C025430","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,1996,"8871601","The effect of a selective estrogen receptor modulator on the progression of spontaneous autoimmune disease in MRL lpr/lpr mice.","8871601",40]
["Lye","Lye","D008191","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1979,"520646","[Measurement of the electrical impedance for a determination of the skin injuries caused by lyes].","520646",40]
["lysoGM1 ganglioside","lysoGM1 ganglioside","C029465","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11168398","Characterization of the reversible nature of the reaction catalyzed by sphingolipid ceramide N-deacylase. A novel form of reverse hydrolysis reaction.","11168398",40]
["Mafenide","Mafenide","D008272","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"2966158","Mafenide-induced pseudochondritis.","2966158",40]
["Magnesium Chloride","Magnesium Chloride","D015636","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"19140515","[Regenerating activity of hydrophilic bischofit mineral ointment in the treatment of acute local cryotrauma].","19140515",40]
["Magnesium Sulfate","Magnesium Sulfate","D008278","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9577281","Modulation by magnesium of N-methyl-D-aspartate receptors in developing human brain.","9577281",40]
["maleimide-oligo(ethylene glycol)","maleimide-oligo(ethylene glycol)","C478641","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12643748","Maleimide-oligo(ethylene glycol) derivatives of camptothecin as albumin-binding prodrugs: synthesis and antitumor efficacy.","12643748",40]
["Malondialdehyde","Malondialdehyde","D008315","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2012,"22540842","Increased oxidative stress condition found in different stages of HIV disease in patients undergoing antiretroviral therapy in Umuahia (Nigeria).","22540842",40]
["mammeisin","mammeisin","C001878","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28889056","Voltammetric behavior of Mammeisin (MA) at a glassy carbon electrode and its interaction with Bovine Serum Albumin (BSA).","28889056",40]
["manganese chloride","manganese chloride","C025340","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2014,"24603521","Manganese oxidation state as a cause of irritant patch test reactions.","24603521",40]
["mangostin","mangostin","C021053","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27584012","α-Mangostin Extraction from the Native Mangosteen (Garcinia mangostana L.) and the Binding Mechanisms of α-Mangostin to HSA or TRF.","27584012",40]
["Mannose","Mannose","D008358","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,1999,"10383411","Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells.","10383411",40]
["Mannose","Mannose","D008358","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2016,"26865006","Mannosylation Allows for Synergic (CD44/C-Type Lectin) Uptake of Hyaluronic Acid Nanoparticles in Dendritic Cells, but Only upon Correct Ligand Presentation.","26865006",40]
["Mannose","Mannose","D008358","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21715597","Removal of two high-mannose N-linked glycans on gp120 renders human immunodeficiency virus 1 largely resistant to the carbohydrate-binding agent griffithsin.","21715597",40]
["Mannose","Mannose","D008358","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4751278","Carbohydrate-induced conformational change in concanavalin A.","4751278",40]
["Mannose","Mannose","D008358","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"25381907","Mannose-modified chitosan microspheres enhance OprF-OprI-mediated protection of mice against Pseudomonas aeruginosa infection via induction of mucosal immunity.","25381907",40]
["maraviroc","maraviroc","C502411","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2012,"22948867","Effect of maraviroc on HIV disease progression-related biomarkers.","22948867",40]
["marbofloxacin","marbofloxacin","C080260","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25411109","Pharmacokinetics of marbofloxacin after intravenous and intramuscular administration in Hanwoo, Korean native cattle.","25411109",40]
["Maytansine","Maytansine","D008453","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"985482","Binding of maytansine to rat brain tubulin.","985482",40]
["Measles Vaccine","Measles Vaccine","D008458","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1963,"14083427","KILLED MEASLES-VIRUS VACCINE.","14083427",40]
["Measles Vaccine","Measles Vaccine","D008458","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2004,"15041159","Influence of HLA-DRB1 alleles on lymphoproliferative responses to a naturally processed and presented measles virus phosphoprotein in measles immunized individuals.","15041159",40]
["Measles Vaccine","Measles Vaccine","D008458","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"25954009","Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality.","25954009",40]
["Mebendazole","Mebendazole","D008463","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,2,1978,"703692","[Host immune response to Trichinella parasitization and its alteration under the influence of of mebendazole. i. The development of cellular and humoral immune reactions in mice infested with Trichinella spiralis].","703692",40]
["Mechlorethamine","Mechlorethamine","D008466","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1997,"9049058","Nitrogen mustard-mediated mutagenesis in human T-lymphocytes in vitro.","9049058",40]
["medicarpin","medicarpin","C047353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26241182","LC-ESI-MS/MS method for bioanalytical determination of osteogenic phytoalexin, medicarpin, and its application to preliminary pharmacokinetic studies in rats.","26241182",40]
["Meglumine","Meglumine","D008536","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21726098","Comparative histological and immunohistochemical changes of dry type cutaneous leishmaniasis after administration of meglumine antimoniate, imiquimod or combination therapy.","21726098",40]
["melanogen","melanogen","C009904","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6198833","Protein-bound dopa and 5-S-cysteinyldopa in non-melanogenic tissues.","6198833",40]
["meloxicam","meloxicam","C065757","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21453256","Meloxicam carbopol-based gels: characterization and evaluation.","21453256",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C85379,B85379)","v":"Meperidine"},"Meperidine","D008614","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J85379,K85379)","v":"Protein Binding"},"D011485","Protein Binding",1,1,1987,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q85379,Q85379)","v":"3600099"},"Disposition of pethidine in man under acidic urinary pH. 3. A comparison of pharmacokinetics among Caucasian, Chinese and Indian subjects.","3600099",40]
["Mephenytoin","Mephenytoin","D008617","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1951,"14873548","Occurrence of skin pigmentation during mesantoin therapy.","14873548",40]
["Mercaptoethanol","Mercaptoethanol","D008623","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1982,"6982245","Restoration of impaired immune functions in aging animals. VI. Differential potentiating effect of 2-mercaptoethanol on young and old murine spleen cells.","6982245",40]
["Mercaptopurine","Mercaptopurine","D015122","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1972,"4625308","Antimetabolite therapy in the post-myocardial-infarction syndrome.","4625308",40]
["Mercaptopurine","Mercaptopurine","D015122","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"25846055","Oral administration of non-absorbable delayed release 6-mercaptopurine is locally active in the gut, exerts a systemic immune effect and alleviates Crohn's disease with low rate of side effects: results of double blind Phase II clinical trial.","25846055",40]
["Mercuric Chloride","Mercuric Chloride","D008627","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1990,"2088476","Spontaneous lymphocytic infiltrates of oral mucosa in HgCl2 induced autoimmunity of BN rats: phenotypic characteristics and contact hypersensitivity to Hg.","2088476",40]
["Mercuric Chloride","Mercuric Chloride","D008627","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1998,"9878595","Mercuric chloride induces apoptosis in human T lymphocytes: evidence of mitochondrial dysfunction.","9878595",40]
["meso-tetrakis(1-methyl-4-pyridiniumyl)porphyrin","meso-tetrakis(1-methyl-4-pyridiniumyl)porphyrin","C092399","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12080127","Rotation of periphery methylpyridine of meso-tetrakis(n-N-methylpyridiniumyl)porphyrin (n = 2, 3, 4) and its selective binding to native and synthetic DNAs.","12080127",40]
["Metaraminol","Metaraminol","D008680","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1971,"4327962","Effects of angiotensin infusion on catecholamine uptake and reactivity in blood vessels.","4327962",40]
["methacrylonitrile","methacrylonitrile","C008385","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2926097","Disposition of methacrylonitrile in rats and distribution in blood components.","2926097",40]
["Methadone","Methadone","D008691","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7193106","Methadone binding to orosomucoid (alpha 1-acid glycoprotein): determinant of free fraction in plasma.","7193106",40]
["Methamphetamine","Methamphetamine","D008694","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2009,"19811410","Proteomic analyses of the effects of drugs of abuse on monocyte-derived mature dendritic cells.","19811410",40]
["Methane","Methane","D008697","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4441088","Chemical modification of electric eel acetylcholinesterase by tetranitromethane.","4441088",40]
["Methanol","Methanol","D000432","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1953,"13072602","Purification of secretin by freezing out of impurities from methanolic solution at-80 degree C.","13072602",40]
["Methicillin","Methicillin","D008712","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3947051","[Microcalorimetric study of the effect of temperature on methicillin binding with human serum albumin].","3947051",40]
["Methimazole","Methimazole","D008713","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1986,"3098461","Effect of the anti-thyroid drug methimazole on interleukin-1 and interleukin-2 levels in vitro.","3098461",40]
["Methotrexate","Methotrexate","D008727","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2004,"14734779","Nucleotide sequencing of psoriatic arthritis tissue before and during methotrexate administration reveals a complex inflammatory T cell infiltrate with very few clones exhibiting features that suggest they drive the inflammatory process by recognizing autoantigens.","14734779",40]
["Methotrexate","Methotrexate","D008727","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1972,"4260377","[Damage due to treatment of psoriasis with folic acid antagonists].","4260377",40]
["Methotrexate","Methotrexate","D008727","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12203581","A bacterial small-molecule three-hybrid system.","12203581",40]
["Methotrexate","Methotrexate","D008727","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6398629","Methotrexate. I. Pharmacology and pharmacokinetics.","6398629",40]
["Methotrexate","Methotrexate","D008727","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"7396531","Binding properties of the 5-methyltetrahydrofolate/methotrexate transport system in L1210 cells.","7396531",40]
["Methotrexate","Methotrexate","D008727","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"24903472","A case of linear atrophoderma of Moulin successfully treated with methotrexate.","24903472",40]
["Methotrexate","Methotrexate","D008727","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2014,"24449571","Global molecular effects of tocilizumab therapy in rheumatoid arthritis synovium.","24449571",40]
["Methotrexate","Methotrexate","D008727","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1997,"9669212","Long-term exposure to methotrexate induces immunophenotypic changes, decreased methotrexate uptake and increased dihydrofolate gene copy number in Jurkat T cells.","9669212",40]
["Methoxsalen","Methoxsalen","D008730","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22310461","Effect of polyamidoamine dendrimer G3 and G4 on skin permeation of 8-methoxypsoralene--in vivo study.","22310461",40]
["Methoxsalen","Methoxsalen","D008730","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1979,"526353","Photocarcinogenesis by methoxypsoralen, neutral red and proflavine.","526353",40]
["Methoxsalen","Methoxsalen","D008730","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2669376","Methoxsalen and extracorporeal photoactivation in the treatment of cutaneous T-cell lymphoma.","2669376",40]
["methyl arachidonylfluorophosphonate","methyl arachidonylfluorophosphonate","C104810","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17158103","Closing the gate to the active site: effect of the inhibitor methoxyarachidonyl fluorophosphonate on the conformation and membrane binding of fatty acid amide hydrolase.","17158103",40]
["methyl isobutyl ketone","methyl isobutyl ketone","C005458","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25797582","Methyl isobutyl ketone exposure-related increases in specific measures of α2u-globulin (α2u) nephropathy in male rats along with in vitro evidence of reversible protein binding.","25797582",40]
["methyl(acetoxymethyl)nitrosamine","methyl(acetoxymethyl)nitrosamine","C014659","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10490506","Treatment of human cells with N-Nitroso(acetoxymethyl)methylamine: distribution patterns of piperidine-sensitive DNA damage at the nucleotide level of resolution are related to the sequence context.","10490506",40]
["methyl-beta-cyclodextrin","methyl-beta-cyclodextrin","C108732","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2002,"11801652","Induction of MHC class I presentation of exogenous antigen by dendritic cells is controlled by CD4+ T cells engaging class II molecules in cholesterol-rich domains.","11801652",40]
["methyl-beta-cyclodextrin","methyl-beta-cyclodextrin","C108732","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17762176","Methyl-beta-cyclodextrin increases permeability of Caco-2 cell monolayers by displacing specific claudins from cholesterol rich domains associated with tight junctions.","17762176",40]
["Methylcholanthrene","Methylcholanthrene","D008748","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1970,"4394040","Nature of the water-soluble metabolites of 7,12-dimethylbenza(a)-anthracene formed by liver microsomes of normal and 3-methylcholanthrene-treated rats.","4394040",40]
["Methylcholanthrene","Methylcholanthrene","D008748","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1953,"13232432","[Effect of carcinogens (benzopyrene and methylcholanthrene) on spermophile; impossible induction of subcutaneous malignant tumor].","13232432",40]
["Methylene Blue","Methylene Blue","D008751","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1996,"8855335","Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines.","8855335",40]
["methylethyl ketone","methylethyl ketone","C005222","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1986,"2948773","Contact urticaria from methyl ethyl ketone.","2948773",40]
["Methylnitronitrosoguanidine","Methylnitronitrosoguanidine","D008769","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1988,"2897625","Transformation studies on human fibroblasts from familial polyposis coli patients and normal donors.","2897625",40]
["methylparaben","methylparaben","C015358","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2007,"17186576","Effects of methyl paraben on skin keratinocytes.","17186576",40]
["Methylphenidate","Methylphenidate","D008774","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18282769","Methylphenidate DAT binding in adolescents with Attention-Deficit/ Hyperactivity Disorder comorbid with Substance Use Disorder--a single photon emission computed tomography with [Tc(99m)]TRODAT-1 study.","18282769",40]
["Methylprednisolone","Methylprednisolone","D008775","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1983,"6218809","Local skin rash after intraarticular methyl prednisolone acetate injection in a patient with rheumatoid arthritis.","6218809",40]
["Methylprednisolone","Methylprednisolone","D008775","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1975,"1091685","Histologic studies of human skin test responses to ragweed and compound 48/80. II. Effects of corticosteroid therapy.","1091685",40]
["Methylprednisolone","Methylprednisolone","D008775","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1993,"8472630","Immunoprotection in spontaneous remission of type 1 diabetes: long-term follow-up results.","8472630",40]
["Methylthiouracil","Methylthiouracil","D008779","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1970,"5475755","The influence of thyroactive substances on the induction of cervico-vaginal tumours in intact and castrate rats.","5475755",40]
["methysticin","methysticin","C076881","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21908763","Methysticin and 7,8-dihydromethysticin are two major kavalactones in kava extract to induce CYP1A1.","21908763",40]
["Metronidazole","Metronidazole","D008795","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1975,"1195110","Binding of metronidazole and its derivatives to plasma proteins: an assessment of drug binding phenomenon.","1195110",40]
["Metyrapone","Metyrapone","D008797","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"182488","Binding of a metyrapone spin label to microsomal cytochrome P-450.","182488",40]
["mezerein","mezerein","C011309","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2507191","Comparison of octahydromezerein and mezerein as protein kinase C activators and as mouse skin tumor promoters.","2507191",40]
["MF59 oil emulsion","MF59 oil emulsion","C089950","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2013,"23684834","The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect.","23684834",40]
["Mianserin","Mianserin","D008803","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"3931147","Mianserin protein binding in serum and plasma from healthy subjects and patients with depression and rheumatoid arthritis.","3931147",40]
["Midazolam","Midazolam","D008874","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1992,"1329119","Effects of midazolam on T-cell immunosuppressive response to surgical stress in mice.","1329119",40]
["Mifepristone","Mifepristone","D015735","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1993,"8506282","In vivo evidence against the existence of antiprogestins disrupting receptor binding to DNA.","8506282",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C88899,B88899)","v":"Mineral Oil"},"Mineral Oil","D008899","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J88899,K88899)","v":"Skin"},"D012867","Skin",0,1,1980,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q88899,Q88899)","v":"6454168"},"[Effect of mineral oil on mouse skin from its histochemical aspect].","6454168",40]
["Minocycline","Minocycline","D008911","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,1,2010,"19665822","Minocycline-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome with persistent myocarditis.","19665822",40]
["minor H antigen H60","minor H antigen H60","C114735","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"11021531","Differences that matter: major cytotoxic T cell-stimulating minor histocompatibility antigens.","11021531",40]
["Minoxidil","Minoxidil","D008914","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1988,"2975213","Pruritic rash with actinic keratosis and impending exfoliation in a patient with hypertension managed with minoxidil.","2975213",40]
["mithramycin A","mithramycin A","C066851","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17893516","Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells.","17893516",40]
["Mitomycin","Mitomycin","D016685","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2009,"19825097","Delayed hypersensitivity to Mitomycin C.","19825097",40]
["Mitomycin","Mitomycin","D016685","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1987,"3100710","Partial characterization of a mitomycin-C resistant T cell.","3100710",40]
["Mitoxantrone","Mitoxantrone","D008942","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2004,"15261556","Mechanisms of mitoxantrone in multiple sclerosis--what is known?","15261556",40]
["modafinil","modafinil","C048833","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23110414","Aryl-heteroaryl derivatives as novel wake-promoting agents.","23110414",40]
["Mometasone Furoate","Mometasone Furoate","D000068656","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2001,"11422529","Investigator-masked comparison of tazarotene gel q.d. plus mometasone furoate cream q.d. vs. mometasone furoate cream b.i.d. in the treatment of plaque psoriasis.","11422529",40]
["monocyte-macrophage differentiation antigen","monocyte-macrophage differentiation antigen","C036763","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23762286","CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver.","23762286",40]
["monomethoxypolyethylene glycol","monomethoxypolyethylene glycol","C028210","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2012,"22264524","The potential utility of methoxypoly(ethylene glycol)-mediated prevention of rhesus blood group antigen RhD recognition in transfusion medicine.","22264524",40]
["monoperoxysulfate","monoperoxysulfate","C071517","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"11288688","[Evaluation of allergic sensitivity to the virkon disinfectant preparation widely used in Poland].","11288688",40]
["monorden","monorden","C035359","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17683942","Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol.","17683942",40]
["montelukast","montelukast","C093875","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1999,"10051701","The effect of montelukast (MK-0476), a cysteinyl leukotriene receptor antagonist, on allergen-induced airway responses and sputum cell counts in asthma.","10051701",40]
["Morphine","Morphine","D009020","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"19995896","Morphine disrupts interleukin-23 (IL-23)/IL-17-mediated pulmonary mucosal host defense against Streptococcus pneumoniae infection.","19995896",40]
["Morphine","Morphine","D009020","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17028301","Morphine administration alters the profile of hippocampal postsynaptic density-associated proteins: a proteomics study focusing on endocytic proteins.","17028301",40]
["Morphine","Morphine","D009020","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8982659","Influence of nitric oxide on transepithelial transport in toad skin: effects of cholinergic agents and morphine.","8982659",40]
["Morphine","Morphine","D009020","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1991,"1950731","Opiates, human peripheral blood mononuclear cells, and HIV.","1950731",40]
["morphine propionate","morphine propionate","C523259","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"17637185","Ester prodrugs of morphine improve transdermal drug delivery: a mechanistic study.","17637185",40]
["Mumps Vaccine","Mumps Vaccine","D009108","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2001,"11528592","Immune responses to measles and mumps vaccination of infants at 6, 9, and 12 months.","11528592",40]
["muscarinic toxin-like protein 3","muscarinic toxin-like protein 3","C418969","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"11082188","Muscarinic toxin-like proteins from cobra venom.","11082188",40]
["Mycobacterium tuberculosis antigens","Mycobacterium tuberculosis antigens","C072681","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2010,"20176745","PE_PGRS antigens of Mycobacterium tuberculosis induce maturation and activation of human dendritic cells.","20176745",40]
["Mycobacterium tuberculosis antigens","Mycobacterium tuberculosis antigens","C072681","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2016,"27593157","Strategies to enhance immunogenicity of cDNA vaccine encoded antigens by modulation of antigen processing.","27593157",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C90499,B90499)","v":"mycobactins"},"mycobactins","C018608","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J90499,K90499)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2006,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q90499,Q90499)","v":"16923875"},"The structure of MbtI from Mycobacterium tuberculosis, the first enzyme in the biosynthesis of the siderophore mycobactin, reveals it to be a salicylate synthase.","16923875",40]
["Mycophenolic Acid","Mycophenolic Acid","D009173","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2000,"11032062","Treatment of recalcitrant ulcers in pyoderma gangrenosum with mycophenolate mofetil and autologous keratinocyte transplantation on a hyaluronic acid matrix.","11032062",40]
["Mycophenolic Acid","Mycophenolic Acid","D009173","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8681386","Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid.","8681386",40]
["Mycophenolic Acid","Mycophenolic Acid","D009173","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"7506264","Antigen-specific deletion of cloned T cells using peptide-toxin conjugate complexed with purified class II major histocompatibility complex antigen.","7506264",40]
["Mycoplasma arthritidis mitogen","Mycoplasma arthritidis mitogen","C052996","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1987,"3312095","Genetic control of T cell activation induced by Mycoplasma arthritidis.","3312095",40]
["Myristic Acid","Myristic Acid","D019814","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"26423150","Immunosuppression and Aberrant T Cell Development in the Absence of N-Myristoylation.","26423150",40]
["myristoyllysophosphatidylcholine","myristoyllysophosphatidylcholine","C035255","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25975280","Low affinity binding of plasma proteins to lipid-coated quantum dots as observed by in situ fluorescence correlation spectroscopy.","25975280",40]
["N-(11-cyano-2,2,6a,6b,9,9,12a-heptmethyl-10,14-dioxo-1,3,4,5,6a,6b,7,8,8a,9,10,12a,14,14a,14b-hexadecahydro-2H-picen-4a-yl)-2-2-difluoropropionamide","N-(11-cyano-2,2,6a,6b,9,9,12a-heptmethyl-10,14-dioxo-1,3,4,5,6a,6b,7,8,8a,9,10,12a,14,14a,14b-hexadecahydro-2H-picen-4a-yl)-2-2-difluoropropionamide","C000589490","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2015,"26170027","Topical application of RTA 408 lotion activates Nrf2 in human skin and is well-tolerated by healthy human volunteers.","26170027",40]
["N-(2-chloroethyl)-N'-(3-phosphopropyl)ethylenediamine","N-(2-chloroethyl)-N'-(3-phosphopropyl)ethylenediamine","C079884","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1993,"8441736","Inhibition of the vitamin B12 binding capacity of proteins by the hydrolysis product of cyclophosphamide.","8441736",40]
["N-(3-((2-benzo(1,3)dioxol-5-ylethyl)(3-(1-methyl-3-oxo-1,3-dihydroisoindol-2-yl)propionyl)amino)-1-benzyl-2-(hydroxylpropyl))-4-benzyloxy-3,5-dimethoxybenzamide","N-(3-((2-benzo(1,3)dioxol-5-ylethyl)(3-(1-methyl-3-oxo-1,3-dihydroisoindol-2-yl)propionyl)amino)-1-benzyl-2-(hydroxylpropyl))-4-benzyloxy-3,5-dimethoxybenzamide","C570102","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21264482","Computational analysis of aspartic protease plasmepsin II complexed with EH58 inhibitor: a QM/MM MD study.","21264482",40]
["N(4)-acetylsulfadimethoxine","N(4)-acetylsulfadimethoxine","C038180","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2743500","Characterization of binding sites for sulfadimethoxine and its major metabolite, N4-acetylsulfadimethoxine, on human and rabbit serum albumin.","2743500",40]
["N-(4-cyano-benzo(b)thiophene-2-carbonyl)guanidine","N-(4-cyano-benzo(b)thiophene-2-carbonyl)guanidine","C507425","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17828714","Dose-dependent pharmacokinetics of a new Na+/H+ exchanger inhibitor KR-33028 in rats.","17828714",40]
["N-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo(2,1-a)isoindol-9-yl)-N'-pyridin-2-ylurea","N-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo(2,1-a)isoindol-9-yl)-N'-pyridin-2-ylurea","C443683","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11741479","Structure-based generation of a new class of potent Cdk4 inhibitors: new de novo design strategy and library design.","11741479",40]
["N,N-diacetylchitobiose","N,N-diacetylchitobiose","C010913","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"7118879","Virtual coupling in the 1H NMR spectrum of N,N'-diacetyl chitobioside. Application to glycopeptides.","7118879",40]
["N,N-dimethyl-4-anisidine","N,N-dimethyl-4-anisidine","C050795","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1993,"7688094","Correlation of carcinogenic potency with mouse-skin 32P-postlabeling and muta-Rmouse lac Z- mutation data for DMBA and its K-region sulphur isostere: comparison with activities observed in standard genotoxicity assays.","7688094",40]
["N-acetylgalactosaminyl-1-4-N-acetylglucosamine","N-acetylgalactosaminyl-1-4-N-acetylglucosamine","C093701","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15265923","LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition.","15265923",40]
["N-acetylmuramic acid","N-acetylmuramic acid","C031651","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22573327","Structural studies on molecular interactions between camel peptidoglycan recognition protein, CPGRP-S, and peptidoglycan moieties N-acetylglucosamine and N-acetylmuramic acid.","22573327",40]
["N-Acetylneuraminic Acid","N-Acetylneuraminic Acid","D019158","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10570219","Conversion of cellular sialic acid expression from N-acetyl- to N-glycolylneuraminic acid using a synthetic precursor, N-glycolylmannosamine pentaacetate: inhibition of myelin-associated glycoprotein binding to neural cells.","10570219",40]
["N-Acetylneuraminic Acid","N-Acetylneuraminic Acid","D019158","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23896748","Sialic acid binding properties of soluble coronavirus spike (S1) proteins: differences between infectious bronchitis virus and transmissible gastroenteritis virus.","23896748",40]
["N-Acetylneuraminic Acid","N-Acetylneuraminic Acid","D019158","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3790067","The influence of N-acetylneuraminic acid on the properties of human orosomucoid.","3790067",40]
["Nafcillin","Nafcillin","D009254","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1968,"4973119","Penicillin allergy. A report of thirteen cases of severe reactions.","4973119",40]
["Nalidixic Acid","Nalidixic Acid","D009268","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6237890","Pharmacokinetic studies of norfloxacin in laboratory animals.","6237890",40]
["Naloxone","Naloxone","D009270","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1983,"6602701","Influence of morphine and naloxone on human peripheral blood T-lymphocytes.","6602701",40]
["NanoGel","NanoGel","C413692","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22118820","Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs.","22118820",40]
["naphthalene","naphthalene","C031721","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"12112628","The influence of maternal exposure to volatile organic compounds on the cytokine secretion profile of neonatal T cells.","12112628",40]
["Naproxen","Naproxen","D009288","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8352821","Pharmacokinetics and pharmacodynamics of naproxen in acute experimental hepatitis.","8352821",40]
["naringenin","naringenin","C005273","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11732902","Structure-guided programming of polyketide chain-length determination in chalcone synthase.","11732902",40]
["NBD-colcemid","NBD-colcemid","C052280","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10694388","NBD-isocolcemid-tubulin interaction: a novel one-step reaction involving no conformational adjustment of reactants.","10694388",40]
["neamine","neamine","C488396","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2005,"16153833","Neamine dimers targeting the HIV-1 TAR RNA.","16153833",40]
["Nelfinavir","Nelfinavir","D019888","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11849916","Determination of nelfinavir free drug concentrations in plasma by equilibrium dialysis and liquid chromatography/tandem mass spectrometry: important factors for method optimization.","11849916",40]
["Neomycin","Neomycin","D009355","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1969,"4242005","Neomycin and framycetin in topical preparations.","4242005",40]
["Neomycin","Neomycin","D009355","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24320996","Protein dynamics are influenced by the order of ligand binding to an antibiotic resistance enzyme.","24320996",40]
["Neopterin","Neopterin","D019798","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1991,"1673120","Neopterin and beta 2-microglobulin as prognostic indices in human immunodeficiency virus type 1 infection.","1673120",40]
["neosurugatoxin","neosurugatoxin","C036793","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9829625","Functional studies on blockade by neosurugatoxin of nicotinic receptors in nitroxidergic and sensory nerve terminals and intramural ganglionic cells.","9829625",40]
["netobimin","netobimin","C049626","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9760064","Sex differences in the disposition of albendazole metabolites in sheep.","9760064",40]
["Nevirapine","Nevirapine","D019829","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23947594","Identification of danger signals in nevirapine-induced skin rash.","23947594",40]
["N-glycolylneuraminyllactosylceramide","N-glycolylneuraminyllactosylceramide","C044298","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2006,"16208470","Role of tumour-associated N-glycolylated variant of GM3 ganglioside in cancer progression: effect over CD4 expression on T cells.","16208470",40]
["Niacin","Niacin","D009525","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22564238","Nicotinic acid: clinical considerations.","22564238",40]
["Niacinamide","Niacinamide","D009536","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2014,"24330088","Acne inversa-like lesions associated with the multi-kinase inhibitor sorafenib.","24330088",40]
["Niacinamide","Niacinamide","D009536","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2017,"28867735","Effects of Ascorbyl-2-phosphate Magnesium on Human Keratinocyte Toxicity and Pathological Changes by Sorafenib.","28867735",40]
["Nicergoline","Nicergoline","D009530","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6885199","Plasma binding of an alpha-blocking agent, nicergoline--affinity for serum albumin and native and modified alpha 1-acid glycoprotein.","6885199",40]
["nicotinamide N-oxide","nicotinamide N-oxide","C037645","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11459668","Nicotinamide N-oxides as CXCR2 antagonists.","11459668",40]
["Nicotine","Nicotine","D009538","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16835356","Beta3 subunits promote expression and nicotine-induced up-regulation of human nicotinic alpha6* nicotinic acetylcholine receptors expressed in transfected cell lines.","16835356",40]
["Nicotine","Nicotine","D009538","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"22085699","Sensitization of epithelial growth factor receptors by nicotine exposure to promote breast cancer cell growth.","22085699",40]
["Nicotine","Nicotine","D009538","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2001,"11737434","Receptor-mediated action of nicotine in human skin.","11737434",40]
["Nifedipine","Nifedipine","D009543","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2015,"26027835","Nifedipine prevents sodium caprate-induced barrier dysfunction in human epidermal keratinocyte cultures.","26027835",40]
["Niflumic Acid","Niflumic Acid","D009544","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2001,"11316692","Niflumic acid and cutaneous reactions in children.","11316692",40]
["Niridazole","Niridazole","D009560","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1975,"1089984","Marked prolongation of skin homograft survival with niridazole. A first report.","1089984",40]
["N-isopropyl-p-phenylenediamine","N-isopropyl-p-phenylenediamine","C056153","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"3378442","A case of allergic isopropyl-p-phenylenediamine (IPPD) dermatitis from a watch strap.","3378442",40]
["Nitric Oxide","Nitric Oxide","D009569","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2004,"15265904","Endogenous nitric oxide protects against T cell-dependent lethality during graft-versus-host disease and idiopathic pneumonia syndrome.","15265904",40]
["Nitric Oxide","Nitric Oxide","D009569","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2002,"12364865","Differential modulation of CD4 and CD8 T-cell proliferation by induction of nitric oxide synthesis in antigen presenting cells.","12364865",40]
["Nitric Oxide","Nitric Oxide","D009569","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2005,"16166326","Nitric oxide sensitizes tumor cells to dendritic cell-mediated apoptosis, uptake, and cross-presentation.","16166326",40]
["Nitric Oxide","Nitric Oxide","D009569","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,2005,"16266380","Exhaled nitric oxide and exercise-induced bronchoconstriction in young male conscripts: association only in atopics.","16266380",40]
["Nitric Oxide","Nitric Oxide","D009569","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1995,"8752505","[Increased production of nitric oxide in the immediate and late asthmatic responses in models of guinea pig experimental asthma].","8752505",40]
["Nitric Oxide","Nitric Oxide","D009569","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11278592","Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells.","11278592",40]
["Nitric Oxide","Nitric Oxide","D009569","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11988094","Nitric oxide inhibits the shedding of the glycosylphosphatidylinositol-anchored dipeptidase from porcine renal proximal tubules.","11988094",40]
["Nitric Oxide","Nitric Oxide","D009569","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"14644391","High glucose induced NF-kappaB DNA-binding activity in HAEC is maintained under low shear stress but inhibited under high shear stress: role of nitric oxide.","14644391",40]
["Nitric Oxide","Nitric Oxide","D009569","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16690332","Dynamics of NO rebinding to the heme domain of NO synthase-like proteins from bacterial pathogens.","16690332",40]
["Nitric Oxide","Nitric Oxide","D009569","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"19946124","Beta-actin association with endothelial nitric-oxide synthase modulates nitric oxide and superoxide generation from the enzyme.","19946124",40]
["Nitric Oxide","Nitric Oxide","D009569","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"21834687","Disruption of caveolae blocks ischemic preconditioning-mediated S-nitrosylation of mitochondrial proteins.","21834687",40]
["Nitric Oxide","Nitric Oxide","D009569","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"2851030","Effect of inositol hexakisphosphate on the spectroscopic properties of the nitric oxide derivative of ferrous naturally glycated human hemoglobin HbA1c.","2851030",40]
["Nitric Oxide","Nitric Oxide","D009569","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8710491","Inhibition of NF-kappaB DNA binding by nitric oxide.","8710491",40]
["Nitric Oxide","Nitric Oxide","D009569","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1997,"9350419","Diethyldithiocarbamate and nitric oxide synergize with oxidants and with membrane-damaging agents to injure mammalian cells.","9350419",40]
["Nitric Oxide","Nitric Oxide","D009569","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2002,"11777962","Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism.","11777962",40]
["Nitric Oxide","Nitric Oxide","D009569","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"7561103","Cytokine and nitric oxide regulation of the immunosuppression in Trypanosoma cruzi infection.","7561103",40]
["Nitric Oxide","Nitric Oxide","D009569","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1996,"8791671","Assay for detection of nitric oxide-induced apoptosis.","8791671",40]
["Nitrilotriacetic Acid","Nitrilotriacetic Acid","D009571","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15142599","Orientated binding of photosynthetic reaction centers on gold using Ni-NTA self-assembled monolayers.","15142599",40]
["Nitrofurazone","Nitrofurazone","D009583","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1980,"7436428","Inhibition of rat skin ornithine decarboxylase by nitrofurazone.","7436428",40]
["Nitroglycerin","Nitroglycerin","D005996","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1984,"6237565","Allergic contact dermatitis secondary to transdermal nitroglycerin.","6237565",40]
["nivalenol","nivalenol","C038405","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,1999,"10696820","Effects of four trichothecene mycotoxins on activation marker expression and cell proliferation of human lymphocytes in culture.","10696820",40]
["N-Methyl-3,4-methylenedioxyamphetamine","N-Methyl-3,4-methylenedioxyamphetamine","D018817","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"21269783","3,4-Methylenedioxymethamphetamine (MDMA) alters acute gammaherpesvirus burden and limits interleukin 27 responses in a mouse model of viral infection.","21269783",40]
["N-methyldiethanolamine","N-methyldiethanolamine","C008430","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1998,"9554055","The skin sensitization potential of four alkylalkanolamines.","9554055",40]
["Nogalamycin","Nogalamycin","D009621","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8913304","Factors affecting DNA sequence selectivity of nogalamycin intercalation: the crystal structure of d(TGTACA)2-nogalamycin2.","8913304",40]
["nonylphenol","nonylphenol","C025256","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"10805991","Nonylphenol affects the granulation pattern of epidermal mucous cells in rainbow trout, Oncorhynchus mykiss.","10805991",40]
["Norepinephrine","Norepinephrine","D009638","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11115406","Diacylglycerol kinase theta is translocated and phosphoinositide 3-kinase-dependently activated by noradrenaline but not angiotensin II in intact small arteries.","11115406",40]
["Norepinephrine","Norepinephrine","D009638","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20215412","Transmembrane segment five serines of the D4 dopamine receptor uniquely influence the interactions of dopamine, norepinephrine, and Ro10-4548.","20215412",40]
["Norepinephrine","Norepinephrine","D009638","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1967,"4291686","Effect of angiotensin and phenoxybenzamine on release of norepinephrine in vessels during sympathetic nerve stimulation.","4291686",40]
["Norepinephrine","Norepinephrine","D009638","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"25691620","Redox-regulated suppression of splenic T-lymphocyte activation in a model of sympathoexcitation.","25691620",40]
["Norethindrone","Norethindrone","D009640","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1972,"5060381","Adrenocortical function studies during the normal menstrual cycle and in women receiving norethindrone with and without mestranol.","5060381",40]
["Nortriptyline","Nortriptyline","D009661","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18076894","Uptake of amitriptyline and nortriptyline with liposomes, proteins, and serum: implications for drug detoxification.","18076894",40]
["Noscapine","Noscapine","D009665","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12183452","Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine.","12183452",40]
["N-retinoylglucosamine","N-retinoylglucosamine","C508934","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2005,"16280019","N-retinoyl-D-glucosamine, a new retinoic acid agonist, mediates topical retinoid efficacy with no irritation on photoaged skin.","16280019",40]
["N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine","N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine","C089665","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2008,"18389479","DiC14-amidine cationic liposomes stimulate myeloid dendritic cells through Toll-like receptor 4.","18389479",40]
["nutlin 3","nutlin 3","C482205","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23653682","In vitro selection of mutant HDM2 resistant to Nutlin inhibition.","23653682",40]
["NYVAC-C vaccine","NYVAC-C vaccine","C572770","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2007,"17224219","Generation and immunogenicity of novel HIV/AIDS vaccine candidates targeting HIV-1 Env/Gag-Pol-Nef antigens of clade C.","17224219",40]
["O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate","O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate","C009618","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17644233","Comparative effects of oral chlorpyrifos exposure on cholinesterase activity and muscarinic receptor binding in neonatal and adult rat heart.","17644233",40]
["octadeca-5,8-dienoic acid","octadeca-5,8-dienoic acid","C008695","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2008,"18287092","Human neutrophils convert the sebum-derived polyunsaturated fatty acid Sebaleic acid to a potent granulocyte chemoattractant.","18287092",40]
["Octopamine","Octopamine","D009655","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4277715","The physiological disposition of p-octopamine in man.","4277715",40]
["octyl 2-cyanoacrylate","octyl 2-cyanoacrylate","C100832","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,1,2016,"27620119","Allergic contact dermatitis caused by Dermabond(®).","27620119",40]
["Ofloxacin","Ofloxacin","D015242","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1759834","Enantioselective disposition of ofloxacin in humans.","1759834",40]
["Okadaic Acid","Okadaic Acid","D019319","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17867706","Isolation and characterization of okadaic acid binding proteins from the marine sponge Halichondria okadai.","17867706",40]
["Oleanolic Acid","Oleanolic Acid","D009828","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2007,"17727365","Simultaneous effect of ursolic acid and oleanolic acid on epidermal permeability barrier function and epidermal keratinocyte differentiation via peroxisome proliferator-activated receptor-alpha.","17727365",40]
["Oleanolic Acid","Oleanolic Acid","D009828","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2010,"19818416","Effects of esculentoside A on autoimmune syndrome induced by Campylobacterjejuni in mice and its modulation on T-lymphocyte proliferation and apoptosis.","19818416",40]
["Oleic Acid","Oleic Acid","D019301","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16843720","Fatty acids bound to human serum albumin and its structural variants modulate apolipoprotein B secretion in HepG2 cells.","16843720",40]
["oleuropein","oleuropein","C002769","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19908866","Synthesis, biological evaluation, and molecular modeling of oleuropein and its semisynthetic derivatives as cyclooxygenase inhibitors.","19908866",40]
["oligomycin A","oligomycin A","C031004","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26883908","Structural Analysis of the Streptomyces avermitilis CYP107W1-Oligomycin A Complex and Role of the Tryptophan 178 Residue.","26883908",40]
["Olopatadine Hydrochloride","Olopatadine Hydrochloride","D000069605","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18268402","The noncompetitive antagonism of histamine H1 receptors expressed in Chinese hamster ovary cells by olopatadine hydrochloride: its potency and molecular mechanism.","18268402",40]
["omega-conotoxin-MVIIC","omega-conotoxin-MVIIC","C075851","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10346894","Effects of chirality at Tyr13 on the structure-activity relationships of omega-conotoxins from Conus magus.","10346894",40]
["Omeprazole","Omeprazole","D009853","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27992223","Revealing the Mechanistic Pathway of Acid Activation of Proton Pump Inhibitors To Inhibit the Gastric Proton Pump: A DFT Study.","27992223",40]
["ONO4819","ONO4819","C487764","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2004,"15196475","Up-regulation of lymphocytic cholinergic activity by ONO-4819, a selective prostaglandin EP4 receptor agonist, in MOLT-3 human leukemic T cells.","15196475",40]
["orantinib","orantinib","C412603","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2002,"12384531","Combined therapy of local and metastatic 4T1 breast tumor in mice using SU6668, an inhibitor of angiogenic receptor tyrosine kinases, and the immunostimulator B7.2-IgG fusion protein.","12384531",40]
["oseltamivir carboxylate","oseltamivir carboxylate","C535162","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21722670","Characterization of the binding affinities of peramivir and oseltamivir carboxylate to the neuraminidase enzyme.","21722670",40]
["OTR4120","OTR4120","C533322","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"27924424","RGTA® or ReGeneraTing Agents mimic heparan sulfate in regenerative medicine: from concept to curing patients.","27924424",40]
["Ouabain","Ouabain","D010042","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1970,"4248267","Inhibitory sites on sodium- and potassium-activated adenosine triphosphatase for chlorpromazine free radical and ouabain.","4248267",40]
["Ouabain","Ouabain","D010042","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4279615","Ouabain-induced inhibition of cardiac (Na+ plus K+)-ATPase and the positive inotropic response.","4279615",40]
["Ouabain","Ouabain","D010042","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6319608","Partial purification and properties of the inhibitors of Na, K-ATPase and ouabain-binding in bovine central nervous system.","6319608",40]
["oxaliplatin","oxaliplatin","C030110","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2005,"16356307","Oxaliplatin induces a delayed immune-mediated hemolytic anemia: a case report and review of the literature.","16356307",40]
["oxaliplatin","oxaliplatin","C030110","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2010,"20924373","A pilot study on the immunogenicity of dendritic cell vaccination during adjuvant oxaliplatin/capecitabine chemotherapy in colon cancer patients.","20924373",40]
["Oxazolone","Oxazolone","D010081","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26462055","Synthesis of novel compounds containing morpholine and 5(4H)-oxazolone rings as potent tyrosinase inhibitors.","26462055",40]
["oxcarbamazepine","oxcarbamazepine","C476610","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,1,2013,"24067479","Lichen sclerosus et atrophicus induced by carbamazepine: a case report.","24067479",40]
["Oxidopamine","Oxidopamine","D016627","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2015,"25681534","Monoaminergic PET imaging and histopathological correlation in unilateral and bilateral 6-hydroxydopamine lesioned rat models of Parkinson's disease: a longitudinal in-vivo study.","25681534",40]
["oxybutynin","oxybutynin","C005419","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2003,"12964894","Transdermal oxybutynin. A viewpoint by Adrian Wagg.","12964894",40]
["Oxymetholone","Oxymetholone","D010110","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"11071398","Oxymetholone modulates cell-mediated immunity in male B6C3F1 mice.","11071398",40]
["Oxytetracycline","Oxytetracycline","D010118","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1966,"5954992","Distribution and excretion of doxycycline in man.","5954992",40]
["Ozone","Ozone","D010126","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2012,"23087018","Site-specific dynamics of CD11b+ and CD103+ dendritic cell accumulations following ozone exposure.","23087018",40]
["Ozone","Ozone","D010126","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2014,"24594710","Early life ozone exposure results in dysregulated innate immune function and altered microRNA expression in airway epithelium.","24594710",40]
["Paclitaxel","Paclitaxel","D017239","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2015,"25559954","Macrophage-produced IL-10 limits the chemotherapy efficacy in breast cancer.","25559954",40]
["Paclitaxel","Paclitaxel","D017239","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2018,"29496750","A localised skin reaction after chemotherapy.","29496750",40]
["Paclitaxel","Paclitaxel","D017239","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2014,"25070196","Expression of recombinant alpha and beta tubulins from the yew Taxus cuspidata and analysis of the microtubule assembly in the presence of taxol.","25070196",40]
["Paclitaxel","Paclitaxel","D017239","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8926579","Binding of taxol to plastic and glass containers and protein under in vitro conditions.","8926579",40]
["Palm Oil","Palm Oil","D000073878","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2016,"26748381","Oral tacrolimus oil formulations for enhanced lymphatic delivery and efficient inhibition of T-cell's interleukin-2 production.","26748381",40]
["Palmitic Acid","Palmitic Acid","D019308","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11296297","Epstein-Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic factors.","11296297",40]
["Palmitic Acid","Palmitic Acid","D019308","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7791757","Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae.","7791757",40]
["PAMAM Starburst","PAMAM Starburst","C104700","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21382406","PAMAM G4 dendrimers affect the aggregation of α-synuclein.","21382406",40]
["pamidronate","pamidronate","C019248","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2005,"16103105","MICA expressed by multiple myeloma and monoclonal gammopathy of undetermined significance plasma cells Costimulates pamidronate-activated gammadelta lymphocytes.","16103105",40]
["pantoprazole","pantoprazole","C064276","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8738854","Pharmacokinetics of pantoprazole in man.","8738854",40]
["Paraffin","Paraffin","D010232","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2531171","Detection of T cells in paraffin wax embedded tissue using antibodies against a peptide sequence from the CD3 antigen.","2531171",40]
["Paraoxon","Paraoxon","D010261","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1993,"8343978","Organophosphate sensitive and insensitive carboxylesterases in human skin.","8343978",40]
["paricalcitol","paricalcitol","C084656","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2009,"19660988","Paricalcitol (19-nor-1,25-dihydroxyvitamin D2) and calcitriol (1,25-dihydroxyvitamin D3) exert potent immunomodulatory effects on dendritic cells and inhibit induction of antigen-specific T cells.","19660988",40]
["Paroxetine","Paroxetine","D017374","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19476548","The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration.","19476548",40]
["Particulate Matter","Particulate Matter","D052638","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2013,"23697695","Effects of ambient fine particles on pulmonary function in children with mild atopic dermatitis.","23697695",40]
["Particulate Matter","Particulate Matter","D052638","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2008,"18948160","Generic construction of single component particles that elicit humoural and cellular immune responses without the need for adjuvants.","18948160",40]
["p-Azobenzenearsonate","p-Azobenzenearsonate","D010132","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,1987,"3100628","Arsonate-specific murine T cell clones. IV. Properties of I-E- and I-A-restricted clones.","3100628",40]
["PCI 32765","PCI 32765","C551803","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2017,"28715249","Durable Molecular Remissions in Chronic Lymphocytic Leukemia Treated With CD19-Specific Chimeric Antigen Receptor-Modified T Cells After Failure of Ibrutinib.","28715249",40]
["p-Dimethylaminoazobenzene","p-Dimethylaminoazobenzene","D004124","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4360359","[Distribution of protein binding carcinogen in primary liver tumors induced by 3'methyl-4-dimethylaminoazobenzene in rats].","4360359",40]
["pelargonic acid","pelargonic acid","C008776","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2018,"29648835","Agonists of G Protein-Coupled Odorant Receptors are Predicted from Chemical Features.","29648835",40]
["Penicillanic Acid","Penicillanic Acid","D010397","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1994,"7868407","Inhibition of the renal excretion of tazobactam by piperacillin.","7868407",40]
["Penicillin G","Penicillin G","D010400","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1992,"1283059","Assessment of histamine release from basophils in whole blood by benzylpenicilloyl poly-L-lysine in penicillin-sensitized patients.","1283059",40]
["Penicillin G","Penicillin G","D010400","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1966,"5976033","[Skin tests in drug allergy: analysis of skin sensitizing antibody using penicillin hapten].","5976033",40]
["Penicillin G Procaine","Penicillin G Procaine","D010402","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1970,"4246947","Treatment of gonorrhoea by penicillin and a renal blocking agent (probenecid).","4246947",40]
["Pentamidine","Pentamidine","D010419","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1992,"1353750","Efficacy and effects on pulmonary function tests of weekly 600 mg aerosol pentamidine as prophylaxis against Pneumocystis carinii pneumonia.","1353750",40]
["Pentamidine","Pentamidine","D010419","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1996,"9182110","HIV-induced cytopathology and viral load in a pentamidine-treated lymphocytic cell line.","9182110",40]
["Pentetic Acid","Pentetic Acid","D004369","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3059448","Stability, protein binding and clearance studies of [99mTc]DTPA. Evaluation of a commercially available dry-kit.","3059448",40]
["Pentoxifylline","Pentoxifylline","D010431","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2007,"18173533","Acute generalized exanthematous pustulosis induced by pentoxifylline.","18173533",40]
["Pentoxifylline","Pentoxifylline","D010431","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1998,"9667590","Synergistic immunomodulatory effects of interferon-beta1b and the phosphodiesterase inhibitor pentoxifylline in patients with relapsing-remitting multiple sclerosis.","9667590",40]
["perfluorodecalin","perfluorodecalin","C008805","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"25275529","Hyperoxygenation attenuated a murine model of atopic dermatitis through raising skin level of ROS.","25275529",40]
["perfluorooctanoic acid","perfluorooctanoic acid","C023036","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"18854981","Fluorescence study on site-specific binding of perfluoroalkyl acids to human serum albumin.","18854981",40]
["Periodic Acid","Periodic Acid","D010504","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2006,"17169163","Protein methylation is required to maintain optimal HIV-1 infectivity.","17169163",40]
["peroxymonosulfate","peroxymonosulfate","C038288","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2004,"15373851","Potassium peroxymonosulfate-induced contact dermatitis.","15373851",40]
["peroxynitric acid","peroxynitric acid","C039642","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"11053771","BCL-2 protects peroxynitrite-treated thymocytes from poly(ADP-ribose) synthase (PARS)-independent apoptotic but not from PARS-mediated necrotic cell death.","11053771",40]
["Pertussis Vaccine","Pertussis Vaccine","D010567","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1976,"970291","Pertussis vaccine pleurisy: a model of delayed hypersensitivity.","970291",40]
["Pertussis Vaccine","Pertussis Vaccine","D010567","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1990,"2257130","Acellular and whole cell pertussis vaccines protect against the lethal effects of intracerebral challenge by two different T-cell dependent humoral routes.","2257130",40]
["Perylene","Perylene","D010569","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"22581390","Laser light activation of a second-generation photosensitiser and its use as a potential photomodulatory agent in skin rejuvenation.","22581390",40]
["Petrolatum","Petrolatum","D010577","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2017,"28619576","Preapplication of white petroleum jelly to adjacent skin to prevent aluminum chloride-induced irritant dermatitis.","28619576",40]
["Petroleum","Petroleum","D010578","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1989,"2533536","Polyamine sensitization in offshore workers handling drilling muds.","2533536",40]
["PH 302","PH 302","C517786","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"17173379","Inhibition of cytochrome P450 3A4 by a pyrimidineimidazole: Evidence for complex heme interactions.","17173379",40]
["Phencyclidine","Phencyclidine","D010622","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10664474","1-[1-(2-Benzo[b]thiopheneyl)cyclohexyl]piperidine hydrochloride (BTCP) yields two active primary metabolites in vivo. Identification and quantification of BTCP primary metabolites in mice plasma, urine, and brain and their affinity for the neuronal dopamine transporter.","10664474",40]
["Phenobarbital","Phenobarbital","D010634","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1984,"6237236","[Hypersensitivity syndrome caused by phenytoins and phenobarbital].","6237236",40]
["Phenobarbital","Phenobarbital","D010634","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3252025","Alpha-1-acid glycoprotein concentrations and protein binding of propranolol in Sprague-Dawley and Dark Agouti rat strains treated by phenobarbital.","3252025",40]
["Phenobarbital","Phenobarbital","D010634","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1969,"5262999","Organic anion-binding protein in rat liver: drug induction and its physiologic consequence.","5262999",40]
["phenol-formaldehyde resin","phenol-formaldehyde resin","C011529","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2017,"28444762","Screening allergic reactions to resol resin based on phenol and formaldehyde in a clinic of occupational dermatology.","28444762",40]
["Phenoxybenzamine","Phenoxybenzamine","D010643","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1986,"3758070","Calcium release from calmodulin and its C-terminal or N-terminal halves in the presence of the calmodulin antagonists phenoxybenzamine and melittin measured by stopped-flow fluorescence with Quin 2 and intrinsic tyrosine. Inhibition of calmodulin-dependent protein kinase of cardiac sarcoplasmic reticulum.","3758070",40]
["phenstatin phosphate","phenstatin phosphate","C112107","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1998,"9572894","Antineoplastic agents. 379. Synthesis of phenstatin phosphate.","9572894",40]
["Phenylbutazone","Phenylbutazone","D010653","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1962,"13886917","[Modification of Rh antigen-antibody reactions].","13886917",40]
["Phenylbutazone","Phenylbutazone","D010653","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1971,"5132879","Biochemical properties of anti-inflammatory drugs. XII. Inhibition of urate binding to human albumin by salicylate and phenylbutazone analogues and some novel anti-antiflammatory drugs.","5132879",40]
["Phenylbutazone","Phenylbutazone","D010653","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1968,"5638560","Effect of anti-rheumatic drugs on experimental lathyrism.","5638560",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C101955,B101955)","v":"Phenylephrine"},"Phenylephrine","D010656","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J101955,K101955)","v":"Drug Eruptions"},"D003875","Drug Eruptions",0,2,1993,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q101955,Q101955)","v":"8365168"},"Allergic contact dermatitis from phenylephrine in a rectal ointment.","8365168",40]
["phenylisothiocyanate","phenylisothiocyanate","C005441","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"7370239","Interaction of phenylisothiocyanate with human erythrocyte band 3 protein. I. Covalent modification and inhibition of phosphate transport.","7370239",40]
["phenylsulfate","phenylsulfate","C025208","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1676666","Rapid, dose-dependent elimination of phenol across the gills, and slow elimination of phenyl sulfate in the urine of phenol-dosed lobsters, Homarus americanus.","1676666",40]
["Phenytoin","Phenytoin","D010672","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,1,2005,"15660903","Drug-induced hypersensitivity syndrome in a premature infant.","15660903",40]
["Phenytoin","Phenytoin","D010672","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1979,"155738","Metabolic activation and covalent binding of phenytoin in the rat gingiva.","155738",40]
["Phenytoin","Phenytoin","D010672","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2751110","Effect of protein binding on the high-performance liquid chromatography of phenytoin and imirestat in human serum by direct injection onto internal surface reversed-phase columns.","2751110",40]
["Phenytoin","Phenytoin","D010672","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1971,"5133553","Variations of serum diphenylhydantoin concentrations in epileptic out-patients.","5133553",40]
["Phenytoin","Phenytoin","D010672","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6825387","Effects of phenytoin, phenobarbital, and ascorbic acid on misonidazole elimination.","6825387",40]
["Phenytoin","Phenytoin","D010672","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1980,"6968202","Phenytoin and formation of T lymphocyte rosettes.","6968202",40]
["Phloretin","Phloretin","D010693","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"19146606","Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin.","19146606",40]
["Phloroglucinol","Phloroglucinol","D010696","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14761950","Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules.","14761950",40]
["Phosgene","Phosgene","D010705","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1989,"2721191","Phosgene (2,5-dichlorophenyl)hydrazone, a new strong sensitizer.","2721191",40]
["phosphatidylinositol 3,4,5-triphosphate","phosphatidylinositol 3,4,5-triphosphate","C060974","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10607590","Phosphatidylinositol polyphosphate binding to the mammalian septin H5 is modulated by GTP.","10607590",40]
["phosphatidylinositol 3-phosphate","phosphatidylinositol 3-phosphate","C055525","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10394369","Phosphatidylinositol 3-phosphate recognition by the FYVE domain.","10394369",40]
["phosphatidylinositol 3-phosphate","phosphatidylinositol 3-phosphate","C055525","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23154468","Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration.","23154468",40]
["Phosphatidylinositol 4,5-Diphosphate","Phosphatidylinositol 4,5-Diphosphate","D019269","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11265244","Endocytosis. Tent pegs for clathrin.","11265244",40]
["Phosphatidylinositol 4,5-Diphosphate","Phosphatidylinositol 4,5-Diphosphate","D019269","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"20926660","Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate.","20926660",40]
["Phosphatidylinositol 4,5-Diphosphate","Phosphatidylinositol 4,5-Diphosphate","D019269","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23564459","Energetics and location of phosphoinositide binding in human Kir2.1 channels.","23564459",40]
["phosphatidylinositol 4-phosphate","phosphatidylinositol 4-phosphate","C037178","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20616805","High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA.","20616805",40]
["phosphatidylinositol 5-phosphate","phosphatidylinositol 5-phosphate","C113567","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22260701","The emerging role of PtdIns5P: another signalling phosphoinositide takes its place.","22260701",40]
["phosphomannan","phosphomannan","C005437","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3606129","Structural study of phosphomannan-protein complex of Citeromyces matritensis containing beta-1,2 linkage. Application of partial acid degradation and acetolysis techniques under mild conditions.","3606129",40]
["phosphorus sesquisulfide","phosphorus sesquisulfide","C033768","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2009,"19706056","Chronic recurrent otitis externa secondary to allergic contact dermatitis to nickel and phosphorus sesquisulfide.","19706056",40]
["Phosphorylcholine","Phosphorylcholine","D010767","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"19995922","Miltefosine efficiently eliminates Leishmania major amastigotes from infected murine dendritic cells without altering their immune functions.","19995922",40]
["Phosphorylcholine","Phosphorylcholine","D010767","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"8977209","Site-directed mutagenesis of the phosphocholine-binding site of human C-reactive protein: role of Thr76 and Trp67.","8977209",40]
["Phosphorylcholine","Phosphorylcholine","D010767","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2016,"27102765","IgM antibodies against malondialdehyde and phosphorylcholine are together strong protection markers for atherosclerosis in systemic lupus erythematosus: Regulation and underlying mechanisms.","27102765",40]
["phylligenin","phylligenin","C532540","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"21060292","Inhibitory effects of phylligenin and quebrachitol isolated from Mitrephora vulpina on platelet activating factor receptor binding and platelet aggregation.","21060292",40]
["Phytic Acid","Phytic Acid","D010833","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19047051","Autocatalytic processing of Clostridium difficile toxin B. Binding of inositol hexakisphosphate.","19047051",40]
["Phytic Acid","Phytic Acid","D010833","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4530677","Organic phosphates and hemoglobin structure-function relationships in the feline.","4530677",40]
["Picibanil","Picibanil","D010844","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2009,"19307995","Clinical grade OK432-activated dendritic cells: in vitro characterization and tracking during intralymphatic delivery.","19307995",40]
["Picibanil","Picibanil","D010844","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1988,"3056221","Immunochemosurgery as a new approach to reasonable treatment of advanced cancer.","3056221",40]
["Picryl Chloride","Picryl Chloride","D010853","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1981,"6164207","Allergic contact dermatitis of the mouse ear.","6164207",40]
["Picryl Chloride","Picryl Chloride","D010853","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2016,"26642795","Percutaneous exposure to high-dose hapten induces systemic immunosuppression through the inhibition of dendritic cell migration.","26642795",40]
["Pilocarpine","Pilocarpine","D010862","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1999,"10354079","Pilocarpine-induced cholinergic sweat secretion compared with emotional sweat secretion in atopic dermatitis.","10354079",40]
["pimecrolimus","pimecrolimus","C117268","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17620098","Inhibition of T-cell activation in vitro in human peripheral blood mononuclear cells by pimecrolimus and glucocorticosteroids and combinations thereof.","17620098",40]
["Pindolol","Pindolol","D010869","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6317366","[Beta adrenergic receptors in the rat myocardium. 1. Optimal conditions for interaction of J-125-labeled hydroxybenzylpindolol with beta adrenergic receptors].","6317366",40]
["piperazine","piperazine","C034930","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1982,"7105689","Contact dermatitis to phenylbutazone-piperazine suppositories (Carudol) and piperazine gel (Carudol).","7105689",40]
["piperidine","piperidine","C032727","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19435660","Quinazolin-4-piperidin-4-methyl sulfamide PC-1 inhibitors: alleviating hERG interactions through structure based design.","19435660",40]
["piperlonguminine","piperlonguminine","C498077","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2018,"29355526","Piperlongumine and some of its analogs inhibit selectively the human immunoproteasome over the constitutive proteasome.","29355526",40]
["Piroxicam","Piroxicam","D010894","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"7720389","Contact allergy to cinnoxicam.","7720389",40]
["Piroxicam","Piroxicam","D010894","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1995,"7720389","Contact allergy to cinnoxicam.","7720389",40]
["PKH 26","PKH 26","C070080","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1998,"9539773","Alloantigen-induced unresponsiveness in cord blood T lymphocytes is associated with defective activation of Ras.","9539773",40]
["plant extract, Houttuynia cordata","plant extract, Houttuynia cordata","C442781","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2014,"25816564","Antioxidant Houttuynia cordata extract upregulates filaggrin expression in an aryl hydrocarbon-dependent manner.","25816564",40]
["Platelet Activating Factor","Platelet Activating Factor","D010972","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2009,"19234179","Ultraviolet B radiation generated platelet-activating factor receptor agonist formation involves EGF-R-mediated reactive oxygen species.","19234179",40]
["Platelet Activating Factor","Platelet Activating Factor","D010972","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2000,"10634803","Platelet-activating factor enhances vascular endothelial growth factor-induced endothelial cell motility and neoangiogenesis in a murine matrigel model.","10634803",40]
["Platelet Activating Factor","Platelet Activating Factor","D010972","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1999,"10454000","Platelet-activating factor plays a role in the mechanism of major histocompatibility complex in T lymphocytes.","10454000",40]
["p-Methoxy-N-methylphenethylamine","p-Methoxy-N-methylphenethylamine","D003189","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1960,"14402485","Further observations on the disruption of rat mesentery mast cells caused by compound 48/80, antigen-antibody reaction, lecithinase A and decylamine.","14402485",40]
["pneumococcal polysaccharide, type III","pneumococcal polysaccharide, type III","C026604","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1984,"6335831","Serum IgM/A, IgA and functionally distinct IgM anti-type III pneumococcal polysaccharide (SIII) antibodies in BALB/c and athymic (nude) mice.","6335831",40]
["PNU 142372","PNU 142372","C116491","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9792098","Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity.","9792098",40]
["Poliovirus Vaccine, Inactivated","Poliovirus Vaccine, Inactivated","D011054","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1988,"3257176","Improvement of four patients with HIV-1 related symptoms after hyperimmunization with killed poliomyelitis (Salk) vaccine.","3257176",40]
["Poloxamer","Poloxamer","D020442","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19332089","Extracellular matrix binding mixed micelles for drug delivery applications.","19332089",40]
["poly(caprolactone)-chitosan-poly(vinyl alcohol)","poly(caprolactone)-chitosan-poly(vinyl alcohol)","C000591493","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"25014084","Tissue engineered poly(caprolactone)-chitosan-poly(vinyl alcohol) nanofibrous scaffolds for burn and cutting wound healing.","25014084",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C105475,B105475)","v":"poly(glucosylethyl methacrylate)"},"poly(glucosylethyl methacrylate)","C090633","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J105475,K105475)","v":"Protein Binding"},"D011485","Protein Binding",1,1,1997,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q105475,Q105475)","v":"9195333"},"The mechanism of anticoagulant activity of a novel heparinoid sulfated glucoside-bearing polymer.","9195333",40]
["poly-4-vinyl-N-ethylpyridine","poly-4-vinyl-N-ethylpyridine","C027968","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7245957","[Modification of the immune response by using an antigen bound to synthetic polyelectrolytes].","7245957",40]
["polyallylamine","polyallylamine","C063994","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23647248","Investigating polymer thiolation in gene delivery.","23647248",40]
["poly-beta-hydroxybutyrate","poly-beta-hydroxybutyrate","C003182","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10416664","Structure and enzymatic degradation of poly(3-hydroxybutyrate) copolymer single crystals with an extracellular PHB depolymerase from Alcaligenes faecalis T1.","10416664",40]
["polydatin","polydatin","C058229","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26833058","Polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9).","26833058",40]
["Polyethylene","Polyethylene","D020959","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2010,"20920411","Effects of occlusion on the skin of atopic dermatitis patients.","20920411",40]
["Polyethyleneimine","Polyethyleneimine","D011094","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"25917525","An in situ gelling liquid crystalline system based on monoglycerides and polyethylenimine for local delivery of siRNAs.","25917525",40]
["polyglycerol","polyglycerol","C043941","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2008,"18279173","A case of allergic contact dermatitis to polyglyceryl laurate.","18279173",40]
["Polyglycolic Acid","Polyglycolic Acid","D011100","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2013,"23500056","PLGA nanoparticles enhance the expression of retinaldehyde dehydrogenase enzymes in dendritic cells and induce FoxP3(+) T-cells in vitro.","23500056",40]
["Polyglycolic Acid","Polyglycolic Acid","D011100","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15841471","Adsorption of poly(ethylene glycol)-modified ribonuclease A to a poly(lactide-co-glycolide) surface.","15841471",40]
["Polyglycolic Acid","Polyglycolic Acid","D011100","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2002,"11792429","Characterization of humoral and cellular immune responses in mice induced by immunization with HIV-1 Nef regulatory protein encapsulated in poly(DL-lactide-co-glycolide) microparticles.","11792429",40]
["polylactic acid-polyglycolic acid copolymer","polylactic acid-polyglycolic acid copolymer","C043435","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2016,"26715415","Activation of Antigen-Specific CD8(+) T Cells by Poly-DL-Lactide/Glycolide (PLGA) Nanoparticle-Primed Gr-1(high) Cells.","26715415",40]
["polylactic acid-polyglycolic acid copolymer","polylactic acid-polyglycolic acid copolymer","C043435","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2013,"23054976","Biodegradable particles as vaccine delivery systems: size matters.","23054976",40]
["polylactic acid-polyglycolic acid copolymer","polylactic acid-polyglycolic acid copolymer","C043435","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"26803409","Photoprotective efficiency of PLGA-curcumin nanoparticles versus curcumin through the involvement of ERK/AKT pathway under ambient UV-R exposure in HaCaT cell line.","26803409",40]
["Polymethyl Methacrylate","Polymethyl Methacrylate","D019904","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2008,"19292373","Hypersensitivity to polymethylmethacrylate following shoulder hemiarthroplasty.","19292373",40]
["poly-N-4-vinylbenzyllactonamide","poly-N-4-vinylbenzyllactonamide","C074112","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11587039","Hepatocyte attachment onto thermosensitive poly(N-isopropylacrylamide-co-N-p-vinylbenzyl-O-beta-D-galactopyranosyl-(1 --&gt; 4)-D-gluconamide).","11587039",40]
["polysialic acid","polysialic acid","C021319","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21940794","Polysialic acid controls NCAM signals at cell-cell contacts to regulate focal adhesion independent from FGF receptor activity.","21940794",40]
["Polytetrafluoroethylene","Polytetrafluoroethylene","D011138","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,1,2013,"23205881","Treatment of contact dermatitis associated with spinal cord stimulator pulse generator--technical note.","23205881",40]
["Polyvinyl Chloride","Polyvinyl Chloride","D011143","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1976,"58987","Effect of phthalate plasticizer on blood compatibility of polyvinyl chloride.","58987",40]
["pomalidomide","pomalidomide","C467566","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25043012","Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.","25043012",40]
["poriferasterol monoglucoside","poriferasterol monoglucoside","C054293","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1957,"13483228","[Behavior and topical reactions of Reichstein's substance F in certain cutaneous zones].","13483228",40]
["Potassium Chloride","Potassium Chloride","D011189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1971,"5288812","Activation of choline acetyltransferase by salts.","5288812",40]
["Potassium Dichromate","Potassium Dichromate","D011192","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1989,"2480254","[The effect of selected irritants on suspended keratinocytes using double vital staining].","2480254",40]
["Povidone","Povidone","D011205","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2007,"17374012","Urticaria and anaphylaxis to povidone in a paracetamol preparation.","17374012",40]
["Povidone","Povidone","D011205","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1966,"5972271","[Skin infiltration by polyvinylpyrrolidone].","5972271",40]
["Povidone-Iodine","Povidone-Iodine","D011206","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"2003110","Povidone-iodine: potential adverse reactions.","2003110",40]
["Practolol","Practolol","D011217","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1974,"4280498","Letter: Report on adverse reactions associated with practolol.","4280498",40]
["Prasugrel Hydrochloride","Prasugrel Hydrochloride","D000068799","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2012,"22811344","Prasugrel-induced rash.","22811344",40]
["precirol","precirol","C009032","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"26700229","Topical Amphotericin B solid lipid nanoparticles: Design and development.","26700229",40]
["Prednisolone","Prednisolone","D011239","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1964,"14223657","HAEMOLYTIC ANAEMIA WITH ACUTE RENAL DISEASE.","14223657",40]
["Prednisolone","Prednisolone","D011239","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1999,"10344492","Contact allergy to prednicarbate: frequency of positive reactions in consecutively-patch-tested patients.","10344492",40]
["Prednisolone","Prednisolone","D011239","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16945177","Effect of plasma lipid on pharmacokinetics of ciclosporin and its relationship with plasma prednisolone level in renal transplant patients.","16945177",40]
["Prednisolone","Prednisolone","D011239","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6349903","Prednisone and prednisolone kinetic observations after liver transplantation.","6349903",40]
["Prednisolone","Prednisolone","D011239","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"10940869","The effect of calcineurin inhibitors and corticosteroids on the differentiation of human dendritic cells.","10940869",40]
["Prednisolone","Prednisolone","D011239","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1991,"1904329","Cyclosporine A and prednisolone inhibit lectin- and alloantigen-induced release of sCD8: correlation with proliferative responses.","1904329",40]
["Prednisolone","Prednisolone","D011239","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1997,"9117012","The effect of treatment with oral corticosteroids on asthma symptoms and airway inflammation.","9117012",40]
["Prednisone","Prednisone","D011241","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1996,"8828529","Long-term oral corticosteroid therapy does not alter the results of immediate-type allergy skin prick tests.","8828529",40]
["Prednisone","Prednisone","D011241","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"936963","[Effect of prednisone and typhoid vaccine on the size of systemic neutrophil granulocyte pool].","936963",40]
["prehispanolone","prehispanolone","C071608","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1992,"1300024","[Proliferation of lymphocytes T and B by prehispanolone LC-5504 of Leonurus hereterophyllus Sweet].","1300024",40]
["Prilocaine","Prilocaine","D011318","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2004,"15606654","Contact urticaria from Emla cream.","15606654",40]
["Prilocaine","Prilocaine","D011318","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2009,"19151306","A comparison of the antimicrobial property of lidocaine/prilocaine cream (EMLA) and an alcohol-based disinfectant on intact human skin flora.","19151306",40]
["proanthocyanidin A1","proanthocyanidin A1","C473739","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2010,"19686816","Immunomodulatory effects of proanthocyanidin A-1 derived in vitro from Rhododendron spiciferum.","19686816",40]
["Probenecid","Probenecid","D011339","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4588853","5-Hydroxyindole acetic acid and homovanillic acid in cerebrospinal fluid in manic-depressive psychosis and the effect of probenecid treatment.","4588853",40]
["Procaine","Procaine","D011343","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1985,"3929282","Procaine effect on the active and passive ionic transport through isolated epithelia.","3929282",40]
["procyanidin","procyanidin","C017674","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"11027573","Influence of oligomer chain length on the antioxidant activity of procyanidins.","11027573",40]
["Promazine","Promazine","D011395","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1972,"4629719","[Cerebral and hepatic fixation of phenothiazine and iminodibenzyl derivatives in rats].","4629719",40]
["propacetamol","propacetamol","C063776","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1997,"9197966","Airborne contact dermatitis from propacetamol.","9197966",40]
["Propanidid","Propanidid","D011410","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1971,"4255777","Apparent anaphylactic reaction to propanidid.","4255777",40]
["Propofol","Propofol","D015742","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"21504123","NMR investigations of amyloid-β peptide interactions with propofol at clinically relevant concentrations with and without aqueous halothane solution.","21504123",40]
["Propoxycaine","Propoxycaine","D011430","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,1,1999,"10030585","Fingertip dermatitis in an ophthalmologist caused by proparacaine.","10030585",40]
["Propranolol","Propranolol","D011433","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1987,"3429058","Serum protein binding of phenytoin, diazepam and propranolol in chronic renal diseases.","3429058",40]
["Propranolol","Propranolol","D011433","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"6267246","The inhibitory effect of propranolol pretreatment on its own metabolism in the rat.","6267246",40]
["Propranolol","Propranolol","D011433","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1978,"719984","The influence of cirrhosis on steady-state blood concentrations of unbound propranolol after oral administration.","719984",40]
["propylene","propylene","C013658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2013,"23726029","The synthesis of isopropylidene mRNA cap analogs modified with phosphorothioate moiety and their evaluation as promoters of mRNA translation.","23726029",40]
["Propylene Glycol","Propylene Glycol","D019946","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26283792","Localization of proteins to the 1,2-propanediol utilization microcompartment by non-native signal sequences is mediated by a common hydrophobic motif.","26283792",40]
["prostaglandin A2","prostaglandin A2","C100008","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2002,"12225793","Cyclopentenone prostaglandins induce caspase activation and apoptosis in dendritic cells by a PPAR-gamma-independent mechanism: regulation by inflammatory and T cell-derived stimuli.","12225793",40]
["Prostaglandin D2","Prostaglandin D2","D015230","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2007,"17250998","Putative mechanism of the itch-scratch circle: repeated scratching decreases the cutaneous level of prostaglandin D2, a mediator that inhibits itching.","17250998",40]
["prostaglandin E3","prostaglandin E3","C033246","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28986997","PGE1 and E3 show lower efficacies than E2 to β-catenin-mediated activity as biased ligands of EP4 prostanoid receptors.","28986997",40]
["Prostaglandins D","Prostaglandins D","D011457","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1987,"2447989","Prostaglandin D2 release from human skin mast cells in response to ionophore A23187.","2447989",40]
["Prostaglandins E","Prostaglandins E","D011458","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"20689756","Effect of eicosapentaenoic acid on E-type prostaglandin synthesis and EP4 receptor signaling in human colorectal cancer cells.","20689756",40]
["Prostaglandins E","Prostaglandins E","D011458","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1992,"1537586","The inhibition of T-lymphocyte proliferation by fatty acids is via an eicosanoid-independent mechanism.","1537586",40]
["Prostaglandins E","Prostaglandins E","D011458","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1981,"6452226","The induction of nonspecific T suppressor lymphocytes by prostaglandin E1.","6452226",40]
["PROSTVAC","PROSTVAC","C588274","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2015,"26111351","Randomized phase II trial of docetaxel with or without PSA-TRICOM vaccine in patients with castrate-resistant metastatic prostate cancer: A trial of the ECOG-ACRIN cancer research group (E1809).","26111351",40]
["protoporphyrin IX","protoporphyrin IX","C028025","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2001,"11298571","Synergistic toxicity of delta-aminolaevulinic acid-induced protoporphyrin IX used for photodiagnosis and hypericum extract, a herbal antidepressant.","11298571",40]
["protoporphyrin IX","protoporphyrin IX","C028025","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23624237","Structural requirements within protoporphyrin IX in the inhibition of heat shock protein 90.","23624237",40]
["pseudolaric acid B","pseudolaric acid B","C058391","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"25895444","Synthesis and biological evaluation of pseudolaric acid B derivatives as potential immunosuppressive agents.","25895444",40]
["p-tert-butyl catechol","p-tert-butyl catechol","C015047","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2001,"11683828","Patch test sensitization caused by para-tertiary-butylcatechol. Results of a prospective study with a dilution series.","11683828",40]
["p-tert-butylphenolformaldehyde resin","p-tert-butylphenolformaldehyde resin","C014273","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1980,"7261462","Contact sensitization to p-tertiary butylphenol (PTBP) resin in plastic nail adhesive.","7261462",40]
["Putrescine","Putrescine","D011700","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11583148","Structure of a human S-adenosylmethionine decarboxylase self-processing ester intermediate and mechanism of putrescine stimulation of processing as revealed by the H243A mutant.","11583148",40]
["pyochelin","pyochelin","C025316","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16139844","Crystal structure at high resolution of ferric-pyochelin and its membrane receptor FptA from Pseudomonas aeruginosa.","16139844",40]
["pyrazolo(1,5-a)pyrimidine","pyrazolo(1,5-a)pyrimidine","C527752","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23639540","Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probe.","23639540",40]
["pyrene","pyrene","C030984","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28554074","Photochemistry and mechanism of designed pyrenyl probe towards promoted cleavage of proteins.","28554074",40]
["Pyridoxal Phosphate","Pyridoxal Phosphate","D011732","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"1003421","Pyridoxal phosphate. 5. 2-Formylethynylphosphonic acid and 2-formylethylphosphonic acid, potent inhibitors of pyridoxal phosphate binding and probes of enzyme topography.","1003421",40]
["Pyridoxal Phosphate","Pyridoxal Phosphate","D011732","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"1262325","13C NMR spectroscopy of labeled pyridoxal 5'-phosphate. Model studies, D-serine dehydratase, and L-glutamate decarboxylase.","1262325",40]
["Pyridoxal Phosphate","Pyridoxal Phosphate","D011732","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1975,"240513","Effects of buffers on aspartate aminotransferase activity and association of the enzyme with pyridoxal phosphate.","240513",40]
["Pyridoxal Phosphate","Pyridoxal Phosphate","D011732","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1971,"5134532","Pyridoxal 5'-phosphate as a site-specific protein reagent for a catalytically critical lysine residue in rabbit muscle phosphoglucose isomerase.","5134532",40]
["Pyridoxal Phosphate","Pyridoxal Phosphate","D011732","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6718404","Aspartate aminotransferase: studies on conformational adaptions and 3H-transfer during transamination.","6718404",40]
["Pyridoxine","Pyridoxine","D011736","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27377327","Novel potent pyridoxine-based inhibitors of AChE and BChE, structural analogs of pyridostigmine, with improved in vivo safety profile.","27377327",40]
["Pyrilamine","Pyrilamine","D011738","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,1990,"1968079","Characterization of histamine H1 binding sites on human T lymphocytes by means of 125I-iodobolpyramine. Preferential expression of H1 receptors on CD8 T lymphocytes.","1968079",40]
["Pyrimethamine","Pyrimethamine","D011739","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6416176","Protonated state of methotrexate, trimethoprim, and pyrimethamine bound to dihydrofolate reductase.","6416176",40]
["pyrrolidine","pyrrolidine","C032519","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25782742","trans-(3S,4S)-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part I: prime site exploration using an amino linker.","25782742",40]
["pyrrolo(2,3-a)isoquinoline-2-carboxylic acid hydrazide","pyrrolo(2,3-a)isoquinoline-2-carboxylic acid hydrazide","C525469","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17948983","Inhibition of monometalated methionine aminopeptidase: inhibitor discovery and crystallographic analysis.","17948983",40]
["Quartz","Quartz","D011791","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"16853146","Quantitative FT-IRRAS spectroscopic studies of the interaction of avidin with biotin on functionalized quartz surfaces.","16853146",40]
["quaternium-15","quaternium-15","C018375","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1839267","Occupational contact dermatitis due to quaternium 15 presenting as nail dystrophy.","1839267",40]
["Quercetin","Quercetin","D011794","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2014,"24610745","Eruca sativa and its flavonoid components, quercetin and isorhamnetin, improve skin barrier function by activation of peroxisome proliferator-activated receptor (PPAR)-α and suppression of inflammatory cytokines.","24610745",40]
["Quercetin","Quercetin","D011794","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"26626251","Flavonols Protect Against UV Radiation-Induced Thymine Dimer Formation in an Artificial Skin Mimic.","26626251",40]
["quillaic acid arabinopyranosyl-1-4-arabinopyranosyl-1-3-xylopyranosyl-1-4-rhamnopyranosyl-1-2-fucopyranosyl ester","quillaic acid arabinopyranosyl-1-4-arabinopyranosyl-1-3-xylopyranosyl-1-4-rhamnopyranosyl-1-2-fucopyranosyl ester","C513999","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2006,"16880670","Two new monodesmosidic triterpene saponins from Gypsophila oldhamiana.","16880670",40]
["Quinidine","Quinidine","D011802","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1987,"2960915","[Exfoliative dermatitis caused by quinidine. Description of a clinical case].","2960915",40]
["Quinidine","Quinidine","D011802","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3529516","Evaluation of a rapid ultrafiltration technique for determination of quinidine protein binding and comparison with equilibrium dialysis.","3529516",40]
["Quinine","Quinine","D011803","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1991,"1685525","The influence of alpha 1-acid glycoprotein on quinine and quinidine disposition in the rat isolated perfused liver preparation.","1685525",40]
["quinoline","quinoline","C037219","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26774652","4-Aryl-3-arylsulfonyl-quinolines as negative allosteric modulators of metabotropic GluR5 receptors: From HTS hit to development candidate.","26774652",40]
["quinone","quinone","C004532","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10917648","Quinone-binding sites in membrane proteins: what can we learn from the Rhodopseudomonas viridis reaction centre?","10917648",40]
["Raclopride","Raclopride","D020891","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19520172","Quantitative evaluation of changes in binding potential with a simplified reference tissue model and multiple injections of [11C]raclopride.","19520172",40]
["Raloxifene Hydrochloride","Raloxifene Hydrochloride","D020849","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2005,"16081843","The selective estrogen receptor modulators, tamoxifen and raloxifene, impair dendritic cell differentiation and activation.","16081843",40]
["Ramipril","Ramipril","D017257","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8331554","Central nervous and systemic kinetics of ramipril and ramiprilat in the conscious dog.","8331554",40]
["Ranitidine","Ranitidine","D011899","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1997,"9205741","Action of ebrotidine, ranitidine and cimetidine on the specific binding to histamine H1- and H2-receptors.","9205741",40]
["Reamberin","Reamberin","C549374","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22997921","[Efficacy of combined immunocorrection in the treatment of chronic viral hepatitis C].","22997921",40]
["Reserpine","Reserpine","D012110","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1973,"4588712","Increased acoplasmic transport of H3-dopamine in nigro-neostriatal neurons after reserpine.","4588712",40]
["resiquimod","resiquimod","C402365","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2007,"17023556","TLR7/8 agonists impair monocyte-derived dendritic cell differentiation and maturation.","17023556",40]
["Restylane","Restylane","C445361","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"19999067","Collagen stimulators. Beyond Botox, Juvederm, Restylane and Perlane.","19999067",40]
["resveratrol","resveratrol","C059514","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2014,"25169438","The effect of resveratrol and its methylthio-derivatives on the Nrf2-ARE pathway in mouse epidermis and HaCaT keratinocytes.","25169438",40]
["resveratrol","resveratrol","C059514","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21611669","Effect of ZnO#ZnS QDs heterojunctures on the stilbenes-plasma proteins interactions.","21611669",40]
["resveratrol","resveratrol","C059514","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23829535","Role of AMP-activated protein kinase in ferritin H gene expression by resveratrol in human T cells.","23829535",40]
["Retinaldehyde","Retinaldehyde","D012172","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19766652","Retinal-protein interactions in halorhodopsin from Natronomonas pharaonis: binding and retinal thermal isomerization catalysis.","19766652",40]
["retinol palmitate","retinol palmitate","C014794","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1988,"3224346","Pharmacokinetics and metabolism of retinol administered at a chemopreventive level to normal subjects.","3224346",40]
["Rhamnose","Rhamnose","D012210","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2008,"18178024","Collagen biosynthesis in cell culture: comparison of corneal keratocytes and skin fibroblasts. Effect of rhamnose-rich oligo- and polysaccharides.","18178024",40]
["rheumatoid arthritis nuclear antigen","rheumatoid arthritis nuclear antigen","C030352","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1985,"3919139","Characterization of an epibody. An antiidiotype that reacts with both the idiotype of rheumatoid factors (RF) and the antigen recognized by RF.","3919139",40]
["Rh-Hr Blood-Group System","Rh-Hr Blood-Group System","D012204","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1968,"4974911","[Prevention of serological conflict due to Rh factor incompatibility by administration of domestic anti-Rh (D) immunoglobulin].","4974911",40]
["Rh-Hr Blood-Group System","Rh-Hr Blood-Group System","D012204","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1976,"818313","Blocking of certain antigenic sites in the F(ab) region by combination of univalent fragments of Rh antibodies with red cell antigens.","818313",40]
["rhodioloside","rhodioloside","C009172","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2011,"21711135","Adjuvant effects of salidroside from Rhodiola rosea L. on the immune responses to ovalbumin in mice.","21711135",40]
["ribociclib","ribociclib","C000589651","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2018,"29355400","Clinical efficacy of ribociclib as a first-line therapy for HR-positive, advanced breast cancer.","29355400",40]
["Riboflavin","Riboflavin","D012256","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4367324","The biosynthesis of riboflavin: affinity chromatography purification of GTP-ring-opening enzyme.","4367324",40]
["Ribomunyl","Ribomunyl","C034206","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2005,"16392891","Effects of oral bacterial immunotherapy in children with atopic eczema/dermatitis syndrome : a pilot study.","16392891",40]
["Ribostamycin","Ribostamycin","D012271","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11741285","Ribostamycin inhibits the chaperone activity of protein disulfide isomerase.","11741285",40]
["Rifampin","Rifampin","D012293","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11745918","CYP3A inductive potential of the rifamycins, rifabutin and rifampin, in the rabbit.","11745918",40]
["Rifampin","Rifampin","D012293","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"336370","Kinetic studies of the interaction between rifampicin and DNA-dependent RNA polymerase of Escherichia coli.","336370",40]
["rimexolone","rimexolone","C013769","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2010,"20363256","Rimexolone inhibits proliferation, cytokine expression and signal transduction of human CD4+ T-cells.","20363256",40]
["risarestat","risarestat","C051003","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,1995,"8548397","Anti-inflammatory activity of an orally active peptide sequence from PF-4 on acute inflammation and DTH.","8548397",40]
["Ritonavir","Ritonavir","D019438","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2002,"12059949","Long-term efficacy and safety of ritonavir/indinavir at 400/400 mg twice a day in combination with two nucleoside reverse transcriptase inhibitors as first line antiretroviral therapy.","12059949",40]
["Ro 24-7429","Ro 24-7429","C070024","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1996,"8709290","Resistance of chimpanzee T cells to human immunodeficiency virus type 1 Tat-enhanced oxidative stress and apoptosis.","8709290",40]
["rocaglamide","rocaglamide","C107772","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2014,"24150948","The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints.","24150948",40]
["ropivacaine","ropivacaine","C037663","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"9989343","Recent advances in the pharmacokinetics of local anaesthetics. Long-acting amide enantiomers and continuous infusions.","9989343",40]
["roscovitine","roscovitine","C104586","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"16770643","Study of the inhibition of cyclin-dependent kinases with roscovitine and indirubin-3'-oxime from molecular dynamics simulations.","16770643",40]
["rosiglitazone","rosiglitazone","C089730","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2006,"17042679","Peripheral cytokine expression in autoimmune thyroiditis: effects of in vitro modulation by rosiglitazone and dexamethasone.","17042679",40]
["rosin","rosin","C013893","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"7774198","Allergic contact dermatitis from a wart remover solution.","7774198",40]
["rosin","rosin","C013893","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1992,"1536781","Colophony (rosin) in newspapers may contribute to hand eczema.","1536781",40]
["rotigotine","rotigotine","C047508","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2004,"15063038","Transdermal iontophoresis of rotigotine: influence of concentration, temperature and current density in human skin in vitro.","15063038",40]
["Roxithromycin","Roxithromycin","D015575","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2001,"11360921","Effect of roxithromycin on T lymphocyte proliferation and cytokine production elicited by mite antigen.","11360921",40]
["Rubber","Rubber","D012408","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2005,"16033405","Survey of sulfur-containing rubber accelerator levels in latex and nitrile exam gloves.","16033405",40]
["Rubber","Rubber","D012408","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1993,"8118785","Epidemiology of type IV allergies to rubber chemical additives.","8118785",40]
["Rubber","Rubber","D012408","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1998,"9674395","Latex: a cause of allergic contact eczema in users of natural rubber gloves.","9674395",40]
["Rubber","Rubber","D012408","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"3358474","Disulfiram and allergy to rubber.","3358474",40]
["Rubber","Rubber","D012408","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1995,"7598308","Safe use of latex rubber.","7598308",40]
["Rubber","Rubber","D012408","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,1996,"8774495","Current perspectives on latex allergy.","8774495",40]
["Rubella Vaccine","Rubella Vaccine","D012411","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21539881","Detection of platelet-binding anti-measles and anti-rubella virus IgG antibodies in infants with vaccine-induced thrombocytopenic purpura.","21539881",40]
["Ruthenium Red","Ruthenium Red","D012430","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"8788122","Ruthenium Red potently inhibits immune responses both in vitro and in vivo.","8788122",40]
["S 20098","S 20098","C084711","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"24031039","Synthesis and pharmacological evaluation of a series of the agomelatine analogues as melatonin MT1 /MT2 agonist and 5-HT2C antagonist.","24031039",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C114947,B114947)","v":"safingol"},"safingol","C005682","2_KE",826,2,"Keratinocytes","Activation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J114947,K114947)","v":"Keratinocytes"},"D015603","Keratinocytes",1,3,2015,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q114947,Q114947)","v":"26005054"},"Differential cytotoxicity of long-chain bases for human oral gingival epithelial keratinocytes, oral fibroblasts, and dendritic cells.","26005054",40]
["Salicylic Acid","Salicylic Acid","D020156","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2006,"16758568","Salicylic acid protects the skin from UV damage.","16758568",40]
["Salicylic Acid","Salicylic Acid","D020156","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2014,"25315322","Salicylic acid regulates Arabidopsis microbial pattern receptor kinase levels and signaling.","25315322",40]
["Salicylic Acid","Salicylic Acid","D020156","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1996,"8636021","Autoactivation of the marRAB multiple antibiotic resistance operon by the MarA transcriptional activator in Escherichia coli.","8636021",40]
["salmonella toxin","salmonella toxin","C027952","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"8747478","Biotinylated lipopolysaccharide binds to endotoxin receptor in endothelial and monocytic cells.","8747478",40]
["salvinorin A","salvinorin A","C090499","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21444610","Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin A.","21444610",40]
["sapropterin","sapropterin","C003402","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15779894","A tryptophan that modulates tetrahydrobiopterin-dependent electron transfer in nitric oxide synthase regulates enzyme catalysis by additional mechanisms.","15779894",40]
["sapropterin","sapropterin","C003402","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22162527","Local tetrahydrobiopterin administration augments reflex cutaneous vasodilation through nitric oxide-dependent mechanisms in aged human skin.","22162527",40]
["Saquinavir","Saquinavir","D019258","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2004,"15646074","P-glycoprotein expression affects the intracellular concentration and antiviral activity of the protease inhibitor saquinavir in a T cell line.","15646074",40]
["sarcoma glycoprotein gp96 rejection antigens","sarcoma glycoprotein gp96 rejection antigens","C052646","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9130645","The endoplasmic reticulum-resident stress protein gp96 binds peptides translocated by TAP.","9130645",40]
["sarpogrelate","sarpogrelate","C064294","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2006,"17060854","Induction of indefinite survival of fully mismatched cardiac allografts and generation of regulatory cells by sarpogrelate hydrochloride.","17060854",40]
["SCH 47112","SCH 47112","C109299","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1997,"9341975","SCH 47112, a novel staurosporine derivative, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and epidermal hyperplasia in hairless mouse skin.","9341975",40]
["Scopolamine Hydrobromide","Scopolamine Hydrobromide","D012601","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1989,"2526675","Allergic contact dermatitis caused by transdermal hyoscine.","2526675",40]
["Selenious Acid","Selenious Acid","D020887","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6715362","Selenite binding to carbon monoxide oxidase from Pseudomonas carboxydovorans. Selenium binds covalently to the protein and activates specifically the CO----methylene blue reaction.","6715362",40]
["sephadex","sephadex","C025614","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11445073","A novel approach for purification of recombinant proteins using the dextran-binding domain.","11445073",40]
["Sepharose","Sepharose","D012685","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12768338","A major integral protein of the plant plasma membrane binds flavin.","12768338",40]
["serine repeat antigen 5, Plasmodium falciparum","serine repeat antigen 5, Plasmodium falciparum","C480167","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"26725489","In silico approach to ascertain the calcium dependent role of Plasmodium falciparum SERA5.","26725489",40]
["Serotonin","Serotonin","D012701","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1968,"4185298","The blood platelets in immune hypersensitivity.","4185298",40]
["Serotonin","Serotonin","D012701","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,-1,1996,"8740260","Inhibitory effect of vasoactive intestinal polypeptide and ketanserin on established allergic contact dermatitis in man.","8740260",40]
["Serotonin","Serotonin","D012701","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11412989","The binding of arylguanidines at 5-HT(3) serotonin receptors: a structure-affinity investigation.","11412989",40]
["Serotonin","Serotonin","D012701","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12768277","Treatment improves serotonin transporter binding and reduces binge eating.","12768277",40]
["Serotonin","Serotonin","D012701","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18317590","Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans.","18317590",40]
["Serotonin","Serotonin","D012701","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19494135","PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors.","19494135",40]
["Serotonin","Serotonin","D012701","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2015,"25220079","BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels.","25220079",40]
["Serotonin","Serotonin","D012701","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1978,"361389","The effects of dietary tryptophan and its peripheral metabolism on brain-5-hydroxytryptamine synthesis and function.","361389",40]
["Serotonin","Serotonin","D012701","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1979,"542097","Photoaffinity labeling of serotonin-binding proteins.","542097",40]
["Serotonin","Serotonin","D012701","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1967,"6037228","Effect of 5-hydroxytryptamine on sodium transport across bullfrog skin.","6037228",40]
["Serotonin","Serotonin","D012701","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1992,"1640122","Regulation of the natural killer cell response to interferon-alpha by biogenic amines.","1640122",40]
["sevoflurane","sevoflurane","C009250","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1987,"2965767","[Effects of sevoflurane anesthesia and surgery on plasma beta-endorphin-like immunoreactivity and prolactin levels].","2965767",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C116931,B116931)","v":"Sewage"},"Sewage","D012722","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J116931,K116931)","v":"Protein Binding"},"D011485","Protein Binding",1,1,1997,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q116931,Q116931)","v":"9186950"},"Enterovirus genomes in wastewater: concentration on glass wool and glass powder and detection by RT-PCR.","9186950",40]
["Shikimic Acid","Shikimic Acid","D012765","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11526120","Spectroscopic and kinetic characterization of the bifunctional chorismate synthase from Neurospora crassa: evidence for a common binding site for 5-enolpyruvylshikimate 3-phosphate and NADPH.","11526120",40]
["sialyl Le(a) ganglioside","sialyl Le(a) ganglioside","C064564","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1374233","Comparison of L-selectin and E-selectin ligand specificities: the L-selectin can bind the E-selectin ligands sialyl Le(x) and sialyl Le(a).","1374233",40]
["Sildenafil Citrate","Sildenafil Citrate","D000068677","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21620965","Conformational conversion of PDE5 by incubation with sildenafil or metal ion is accompanied by stimulation of allosteric cGMP binding.","21620965",40]
["Silicon Dioxide","Silicon Dioxide","D012822","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1992,"1332528","Severe hypersensitivity reaction to injectable Gallium 67 in a worker exposed to silica.","1332528",40]
["Silicon Dioxide","Silicon Dioxide","D012822","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15386634","Functionalized nanoparticles for liquid atmospheric pressure matrix-assisted laser desorption/ionization peptide analysis.","15386634",40]
["Silicon Dioxide","Silicon Dioxide","D012822","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1972,"4340499","Effects of  -radiation on a silica-trypsin compound suspended in aqueous buffer.","4340499",40]
["Silicon Dioxide","Silicon Dioxide","D012822","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2014,"25239045","Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein.","25239045",40]
["Silver Nitrate","Silver Nitrate","D012835","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,1965,"14326613","ELECTRON MICROSCOPY OF DENDRITIC CELLS IN THE HUMAN CORNEAL EPITHELIUM: A MODIFIED MASSON'S AMMONIATED SILVER NITRATE STAIN.","14326613",40]
["Silymarin","Silymarin","D012838","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21731736","Silymarin protects epidermal keratinocytes from ultraviolet radiation-induced apoptosis and DNA damage by nucleotide excision repair mechanism.","21731736",40]
["Simethicone","Simethicone","D012841","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2001,"11218002","Allergic contact dermatitis from pharmaceutical grade BHA in Timodine, with no patch test reaction to analytical grade BHA.","11218002",40]
["Simvastatin","Simvastatin","D019821","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2008,"18471827","Amelioration of myocarditis by statin through inhibiting cross-talk between antigen presenting cells and lymphocytes in rats.","18471827",40]
["Singlet Oxygen","Singlet Oxygen","D026082","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25490375","Interaction between Human Serum Albumin and antidiabetic compounds and its influence on the O2((1)Δg)-mediated degradation of the protein.","25490375",40]
["sipuleucel-T","sipuleucel-T","C511774","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2007,"17696825","Immunotherapy for prostate cancer using antigen-loaded antigen-presenting cells: APC8015 (Provenge).","17696825",40]
["Sirolimus","Sirolimus","D020123","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2015,"25536542","Clinically-relevant cyclosporin and rapamycin concentrations enhance regulatory T cell function to a similar extent but with different mechanisms: an in-vitro study in healthy humans.","25536542",40]
["Sirolimus","Sirolimus","D020123","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2014,"24913978","Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infections.","24913978",40]
["Sirolimus","Sirolimus","D020123","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"20620542","Rapamycin inhibits activator protein-1 but not nuclear factor-kappaB activity of mature bone marrow-derived dendritic cells.","20620542",40]
["Sirolimus","Sirolimus","D020123","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17543119","Saccharomyces cerevisiae FKBP12 binds Arabidopsis thaliana TOR and its expression in plants leads to rapamycin susceptibility.","17543119",40]
["Sirolimus","Sirolimus","D020123","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"18768852","Defects in skin gamma delta T cell function contribute to delayed wound repair in rapamycin-treated mice.","18768852",40]
["Sirolimus","Sirolimus","D020123","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2009,"19696647","Indirect antitumor effects of mammalian target of rapamycin inhibitors against Kaposi sarcoma in transplant patients.","19696647",40]
["Sirolimus","Sirolimus","D020123","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2013,"24034707","Rapamycin augments human DC IL-12p70 and IL-27 secretion to promote allogeneic Type 1 polarization modulated by NK cells.","24034707",40]
["Sizofiran","Sizofiran","D012566","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2017,"28738674","Complex Consisting of β-Glucan and Antigenic Peptides with Cleavage Site for Glutathione and Aminopeptidases Induces Potent Cytotoxic T Lymphocytes.","28738674",40]
["SK&F 83959","SK&F 83959","C080703","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2003,"12921854","Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines.","12921854",40]
["Smallpox Vaccine","Smallpox Vaccine","D012900","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1972,"4110939","Vaccinia necrosum and its relationship to impaired immunologic responsiveness.","4110939",40]
["Smallpox Vaccine","Smallpox Vaccine","D012900","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1978,"654521","[Classification and terminology of postvaccinal skin lesions after smallpox vaccination].","654521",40]
["Smallpox Vaccine","Smallpox Vaccine","D012900","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2005,"15993917","Enhanced immunogenicity and protective effect conferred by vaccination with combinations of modified vaccinia virus Ankara and licensed smallpox vaccine Dryvax in a mouse model.","15993917",40]
["Smoke","Smoke","D012906","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2009,"18635815","Adjuvant and anti-inflammatory properties of cigarette smoke in murine allergic airway inflammation.","18635815",40]
["So 1100","So 1100","C090557","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1994,"7961020","Amelioration of both early and late radiation-induced damage to pig skin by essential fatty acids.","7961020",40]
["sodium arsenite","sodium arsenite","C017947","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1990,"2401003","Organization and disorganization of actin filaments in human epidermal keratinocytes: heat-shock treatment and recovery process.","2401003",40]
["Sodium Chloride","Sodium Chloride","D012965","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2013,"23838545","TGFβ/Smad signalling in psoriatic epidermis models exposed to salt water soaks and narrowband ultraviolet B radiation.","23838545",40]
["Sodium Chloride","Sodium Chloride","D012965","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17696453","Effects of cell volume regulating osmolytes on glycerol 3-phosphate binding to triosephosphate isomerase.","17696453",40]
["Sodium Chloride","Sodium Chloride","D012965","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1974,"4156421","Histological and histochemical studies on effects of some storage solutions on human split thickness skin grafts.","4156421",40]
["sodium citrate","sodium citrate","C102006","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12177002","Structure, function, and expression pattern of a novel sodium-coupled citrate transporter (NaCT) cloned from mammalian brain.","12177002",40]
["Sodium Dodecyl Sulfate","Sodium Dodecyl Sulfate","D012967","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,2006,"16787454","Stratum corneum cytokines and skin irritation response to sodium lauryl sulfate.","16787454",40]
["Sodium Dodecyl Sulfate","Sodium Dodecyl Sulfate","D012967","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1975,"1197385","The effect of the presence of the metal prosthetic groups on the subunit structure of bovine superoxide dismutase in sodium dodecyl sulfate.","1197385",40]
["Sodium Dodecyl Sulfate","Sodium Dodecyl Sulfate","D012967","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1795738","[The determination of protein hydrophobicity. 2. Determination of the of protein binding of sodium dodecyl sulfate with the use of the ultracentrifuge].","1795738",40]
["Sodium Dodecyl Sulfate","Sodium Dodecyl Sulfate","D012967","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1979,"574775","Protein-detergent interactions studied by capillary isotachophoresis.","574775",40]
["Sodium Dodecyl Sulfate","Sodium Dodecyl Sulfate","D012967","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20358390","A novel model of inflammatory pain in human skin involving topical application of sodium lauryl sulfate.","20358390",40]
["Sodium Fluoride","Sodium Fluoride","D012969","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2016,"26267553","Modulation and the Underlying Mechanism of T Cells in Thymus of Mice by Oral Administration of Sodium Fluoride.","26267553",40]
["Sodium Hypochlorite","Sodium Hypochlorite","D012973","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2008,"18413113","Self-treatment with bleach by a Latino farmworker.","18413113",40]
["Sodium Iodide","Sodium Iodide","D012974","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2014,"24879795","The thyroxine-containing thyroglobulin peptide (aa 2549-2560) is a target epitope in iodide-accelerated spontaneous autoimmune thyroiditis.","24879795",40]
["Sodium Salicylate","Sodium Salicylate","D012980","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1977,"856048","Effect of sodium salicylate and indomethacin on methotrexate-serum albumin binding.","856048",40]
["sodium sulfate","sodium sulfate","C012036","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"2820467","Sulfate potentiation of the chloride activation of angiotensin converting enzyme.","2820467",40]
["Soot","Soot","D053260","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2014,"24982919","Proinflammatory effects of diesel exhaust nanoparticles on scleroderma skin cells.","24982919",40]
["sorafenib","sorafenib","C471405","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2007,"17962173","Sorafenib: a promising new targeted therapy for renal cell carcinoma.","17962173",40]
["sorafenib","sorafenib","C471405","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2014,"24505595","Perforating folliculitis-like reaction related to sorafenib.","24505595",40]
["sorbitan sesquioleate","sorbitan sesquioleate","C058854","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2008,"19134439","Sorbitan sesquioleate: an emerging contact allergen.","19134439",40]
["Sotalol","Sotalol","D013015","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1976,"988964","Human pharmacokinetics of sotalol.","988964",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C120259,B120259)","v":"Spermidine"},"Spermidine","D013095","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J120259,K120259)","v":"Protein Binding"},"D011485","Protein Binding",1,1,1982,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q120259,Q120259)","v":"6216482"},"Spermidine-condensed phi X174 DNA cleavage by micrococcal nuclease: torus cleavage model and evidence for unidirectional circumferential DNA wrapping.","6216482",40]
["Spermine","Spermine","D013096","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11571284","p11 expression in human bronchial epithelial cells is increased by nitric oxide in a cGMP-dependent pathway involving protein kinase G activation.","11571284",40]
["spermine nitric oxide complex","spermine nitric oxide complex","C091861","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2001,"11481030","TNF-alpha induced endothelial MAdCAM-1 expression is regulated by exogenous, not endogenous nitric oxide.","11481030",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C120451,B120451)","v":"Sphingosine"},"Sphingosine","D013110","3_KE",398,3,"Dendritic Cells","Activation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J120451,K120451)","v":"Dendritic Cells"},"D003713","Dendritic Cells",1,3,2014,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q120451,Q120451)","v":"25207757"},"Modulation of IL-33/ST2-TIR and TLR signalling pathway by fingolimod and analogues in immune cells.","25207757",40]
["Sphingosine","Sphingosine","D013110","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2014,"24177187","Phytosphingosine derivatives ameliorate skin inflammation by inhibiting NF-κB and JAK/STAT signaling in keratinocytes and mice.","24177187",40]
["Sphingosine","Sphingosine","D013110","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"24398588","Phytosphigosine-1-phosphate increases sensitivity of EGF-dependent cell proliferation.","24398588",40]
["Sphingosine","Sphingosine","D013110","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2005,"16323834","Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH.","16323834",40]
["Sphingosine","Sphingosine","D013110","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21576386","Lipid phosphate phosphatase 3 enables efficient thymic egress.","21576386",40]
["sphingosine 1-phosphate","sphingosine 1-phosphate","C060506","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2003,"12648236","Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing.","12648236",40]
["sphingosine 1-phosphate","sphingosine 1-phosphate","C060506","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18263879","Eukaryotic elongation factor 1A interacts with sphingosine kinase and directly enhances its catalytic activity.","18263879",40]
["Spiperone","Spiperone","D013134","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"144230","Alterations in dopaminergic receptors in Huntington's disease.","144230",40]
["Spironolactone","Spironolactone","D013148","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1987,"2955736","[Erythema annulare centrifugum caused by aldactone].","2955736",40]
["splitomicin","splitomicin","C444426","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18269226","Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode.","18269226",40]
["squaric acid dibutyl ester","squaric acid dibutyl ester","C020637","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,1,1993,"8432926","Persistent allergic contact dermatitis from squaric acid dibutyl ester.","8432926",40]
["SRS-A","SRS-A","D013189","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,2003,"14515063","A cysteinyl leukotriene 2 receptor variant is associated with atopy in the population of Tristan da Cunha.","14515063",40]
["Stainless Steel","Stainless Steel","D013193","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2009,"19852615","Face and neck dermatitis from a stainless steel orthodontic appliance.","19852615",40]
["Stainless Steel","Stainless Steel","D013193","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21658801","Adsorption of prion and tissue proteins to surgical stainless steel surfaces and the efficacy of decontamination following dry and wet storage conditions.","21658801",40]
["Starch","Starch","D013213","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16772378","A redox-regulated chloroplast protein phosphatase binds to starch diurnally and functions in its accumulation.","16772378",40]
["Starch","Starch","D013213","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28065507","Crystal Structure of 4,6-α-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from α-Amylases in Oral Bacteria.","28065507",40]
["Staurosporine","Staurosporine","D019311","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,1993,"8102085","Effects of a new protein kinase C inhibitor CGP 41251 on T cell functions: inhibition of activation, growth, and target cell killing.","8102085",40]
["stearyl poly(ethylene oxide)","stearyl poly(ethylene oxide)","C439572","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11853382","Selective binding of albumin on stearyl poly(ethylene oxide) coupling polymer-modified poly(ether urethane) surfaces.","11853382",40]
["sticholysin II","sticholysin II","C404794","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18687335","Calorimetric scrutiny of lipid binding by sticholysin II toxin mutants.","18687335",40]
["Streptomycin","Streptomycin","D013307","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9141668","Properties of C-terminal truncated derivatives of the activator, StrR, of the streptomycin biosynthesis in Streptomyces griseus.","9141668",40]
["Streptozocin","Streptozocin","D013311","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1995,"7540575","Very-low-dose streptozotocin induces diabetes in insulin promoter-mB7-1 transgenic mice.","7540575",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C121859,B121859)","v":"Strychnine"},"Strychnine","D013331","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J121859,K121859)","v":"Skin"},"D012867","Skin",0,1,1995,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q121859,Q121859)","v":"8834483"},"Strychnine-dependent allodynia in the urethane-anesthetized rat is segmentally distributed and prevented by intrathecal glycine and betaine.","8834483",40]
["Succinylcholine","Succinylcholine","D013390","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1969,"5804292","[Changes in the binding properties of plasma proteins in plasma stored under various conditions].","5804292",40]
["Sucrose","Sucrose","D013395","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14767009","Labile iron in parenteral iron formulations: a quantitative and comparative study.","14767009",40]
["Sulfacetamide","Sulfacetamide","D013409","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2009,"19770443","Interaction of topical sulfacetamide and topical dapsone with benzoyl peroxide.","19770443",40]
["Sulfadiazine","Sulfadiazine","D013411","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1982,"7066727","Absorption, excretion and tissue distribution of silver sulphadiazine.","7066727",40]
["Sulfamethazine","Sulfamethazine","D013418","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"4049715","Dose dependent disposition of sulphadimidine and of its N4-acetyl and hydroxy metabolites in plasma and milk of dairy cows.","4049715",40]
["Sulfamethoxazole","Sulfamethoxazole","D013420","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,1998,"9824415","T-cell-mediated cytotoxicity against keratinocytes in sulfamethoxazol-induced skin reaction.","9824415",40]
["Sulfamethoxazole","Sulfamethoxazole","D013420","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2001,"11246171","Induction of delayed-type hypersensitivity to sulfamethoxazole in mice: role of metabolites.","11246171",40]
["Sulfamethoxypyridazine","Sulfamethoxypyridazine","D013421","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7991901","[Pharmacokinetics and plasma protein binding of sulfamethoxypyridazine in camels (Camelus dromedarius)].","7991901",40]
["sulfanilamide","sulfanilamide","C036944","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1960,"13819624","[On the causes of sulfonamide allergy of the skin].","13819624",40]
["Sulfasalazine","Sulfasalazine","D012460","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"20823682","Amelioration of dextran sulfate sodium-induced chronic colitis by sulfasalazine salicylazosulfapyridine via reducing NF-kappaB transcription factor p65 recruitment to ICAM-1 gene promoters.","20823682",40]
["sulfatroxazole","sulfatroxazole","C048358","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3730524","Pharmacokinetics, metabolism and renal excretion of sulfatroxazole and its 5-hydroxy- and N4-acetyl-metabolites in man.","3730524",40]
["Sulfisoxazole","Sulfisoxazole","D013444","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6149912","Influence of protein binding and metabolic interconversion on the disposition of sulfisoxazole and its N4-acetyl metabolite by the isolated perfused rat kidney.","6149912",40]
["sulfoevernan","sulfoevernan","C009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2212988","Sulphoevernan, a polyanionic polysaccharide, and the narcissus lectin potently inhibit human immunodeficiency virus infection by binding to viral envelope protein.","2212988",40]
["sulforafan","sulforafan","C016766","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22453842","Isothiocyanates inhibit psoriasis-related proinflammatory factors in human skin.","22453842",40]
["sulmazole","sulmazole","C029758","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6834245","Nonlinear pharmacokinetics of the new positive inotropic agent sulmazole in the dog.","6834245",40]
["sunitinib","sunitinib","C473478","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2007,"17846013","[Cutaneous side effects of antiangiogenic agents].","17846013",40]
["super glue 3","super glue 3","C014204","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2003,"12877862","Full-thickness skin necrosis of the fingertip after application of superglue.","12877862",40]
["Suramin","Suramin","D013498","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1968,"4239187","[On the influence of acid substances on the binding of promazine to bovine serum albumin].","4239187",40]
["SYBR Green I","SYBR Green I","C098022","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10373438","Functional and physical interaction between WRN helicase and human replication protein A.","10373438",40]
["Tacrine","Tacrine","D013619","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24220172","Novel tacrine-ebselen hybrids with improved cholinesterase inhibitory, hydrogen peroxide and peroxynitrite scavenging activity.","24220172",40]
["Tacrolimus","Tacrolimus","D016559","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2002,"12176404","Tacrolimus treats ongoing allograft rejection by inhibiting interleukin-10 mediated functional cytotoxic cell infiltration.","12176404",40]
["Tacrolimus","Tacrolimus","D016559","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,1994,"7531458","FK506 can inhibit apoptotic cell death induced by the HIV-1 envelope glycoprotein gp120.","7531458",40]
["Tacrolimus","Tacrolimus","D016559","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2006,"17101011","Allergic contact dermatitis from oleyl alcohol in Elidel cream.","17101011",40]
["Tacrolimus","Tacrolimus","D016559","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2003,"12948911","Potential future dermatological indications for tacrolimus ointment.","12948911",40]
["Tacrolimus","Tacrolimus","D016559","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16554484","An analog of a dipeptide-like structure of FK506 increases glial cell line-derived neurotrophic factor expression through cAMP response element-binding protein activated by heat shock protein 90/Akt signaling pathway.","16554484",40]
["Tacrolimus","Tacrolimus","D016559","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7518678","Interaction of tacrolimus(FK506) and its metabolites with FKBP and calcineurin.","7518678",40]
["Tacrolimus","Tacrolimus","D016559","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2007,"17225019","Vulvar lichen sclerosus: 11 women treated with tacrolimus 0.1% ointment.","17225019",40]
["Tacrolimus","Tacrolimus","D016559","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1992,"1371623","Blockade of interleukin-2 production from cloned T cells by cyclosporine and FK 506 assessed by proliferation assays in vitro.","1371623",40]
["Tacrolimus","Tacrolimus","D016559","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2006,"16902298","Targeting T cells to hit B cells: successful treatment of cutaneous plasmacytosis with topical pimecrolimus.","16902298",40]
["Tacrolimus","Tacrolimus","D016559","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2016,"26524694","Different Effects of Tacrolimus on Innate and Adaptive Immune Cells in the Allograft Transplantation.","26524694",40]
["Tacrolimus","Tacrolimus","D016559","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"7531627","IL-8/IL-8 receptor expression in psoriasis and the response to systemic tacrolimus (FK506) therapy.","7531627",40]
["Talaporfin","Talaporfin","C053434","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26736505","Talaporfin sodium binding and photocytotoxicity of photosensitization reaction on myocardial cell under various albumin concentrations and temperature.","26736505",40]
["tamibarotene","tamibarotene","C061133","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2014,"24709559","The synthetic retinoid Am80 delays recovery in a model of multiple sclerosis by modulating myeloid-derived suppressor cell fate and viability.","24709559",40]
["Tamoxifen","Tamoxifen","D013629","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2007,"17297448","Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors.","17297448",40]
["Tamoxifen","Tamoxifen","D013629","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1997,"9355731","Reduction of equilibrative nitrobenzylthioinosine-sensitive nucleoside transporter in tamoxifen-treated MCF-7 cells: an oestrogen-reversible phenomenon.","9355731",40]
["tamsulosin","tamsulosin","C088482","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17666829","Selective binding of tamsulosin to genetic variants of human alpha1-acid glycoprotein.","17666829",40]
["TASP0277308","TASP0277308","C569989","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2012,"22131329","Amelioration of collagen-induced arthritis by a novel S1P1 antagonist with immunomodulatory activities.","22131329",40]
["Taurine","Taurine","D013654","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7294826","Solubilization and characterization of cardiac sarcolemmal taurine-binding proteins.","7294826",40]
["Taurocholic Acid","Taurocholic Acid","D013656","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21464203","Studies in mice, hamsters, and rats demonstrate that repression of hepatic apoA-I expression by taurocholic acid in mice is not mediated by the farnesoid-X-receptor.","21464203",40]
["TB10.4 antigen, Mycobacterium tuberculosis","TB10.4 antigen, Mycobacterium tuberculosis","C501710","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21084459","Human leukocyte antigens A*3001 and A*3002 show distinct peptide-binding patterns of the Mycobacterium tuberculosis protein TB10.4: consequences for immune recognition.","21084459",40]
["Tea","Tea","D013662","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21308350","Diverse inhibition of plasminogen activator inhibitor type 1 by theaflavins of black tea.","21308350",40]
["Tea Tree Oil","Tea Tree Oil","D020947","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2001,"11553113","Safety, efficacy and provenance of tea tree (Melaleuca alternifolia) oil.","11553113",40]
["Tea Tree Oil","Tea Tree Oil","D020947","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21717824","Chronic wound treatment with topical tea tree oil.","21717824",40]
["Technetium Tc 99m Exametazime","Technetium Tc 99m Exametazime","D019690","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24475210","Clinical comparison of 99mTc exametazime and 123I Ioflupane SPECT in patients with chronic mild traumatic brain injury.","24475210",40]
["telithromycin","telithromycin","C106791","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17498392","Dose-dependent pharmacokinetics of telithromycin after intravenous and oral administration to rats: contribution of intestinal first-pass effect to low bioavailability.","17498392",40]
["Temazepam","Temazepam","D013693","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"6117653","Effect of age and gender on disposition of temazepam.","6117653",40]
["tenocyclidine","tenocyclidine","C012058","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8666993","Ethanol-induced inhibition of [3H]thienylcyclohexylpiperidine (TCP) binding to NMDA receptors in brain synaptic membranes and to a purified protein complex.","8666993",40]
["Tenofovir","Tenofovir","D000068698","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2007,"17417971","Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection.","17417971",40]
["tenoxicam","tenoxicam","C032801","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1991,"1838675","[Severe toxic dermatitis caused by tenoxicam (Tilcotil). 3 cases].","1838675",40]
["Terbutaline","Terbutaline","D013726","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2000,"10895896","Pharmacokinetics and pharmacodynamics of terbutaline in healthy horses.","10895896",40]
["Terfenadine","Terfenadine","D016593","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1995,"7783995","Skin reactions and terfenadine.","7783995",40]
["tert-butylcatechol","tert-butylcatechol","C038096","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1984,"6232092","Contact allergy to tertiary-butyl-catechol.","6232092",40]
["Tetanus Toxoid","Tetanus Toxoid","D013745","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1970,"4245833","[The testing of DTP vaccines using rat paw edema in comparison with clinical findings].","4245833",40]
["Tetanus Toxoid","Tetanus Toxoid","D013745","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2017,"29175591","Linking T cell epitopes to a common linear B cell epitope: A targeting and adjuvant strategy to improve T cell responses.","29175591",40]
["Tetanus Toxoid","Tetanus Toxoid","D013745","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1992,"1383258","Quantitation of antigen-specific immune responses in human immunodeficiency virus (HIV)-infected individuals by limiting dilution analysis.","1383258",40]
["Tetanus Toxoid","Tetanus Toxoid","D013745","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1986,"3488346","Antibodies to acetylcholine receptor and tetanus toxoid: in vitro synthesis by thymic lymphocytes.","3488346",40]
["tetrabromobisphenol A","tetrabromobisphenol A","C020806","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2010,"20074668","Effects of tetrabromobisphenol A, a brominated flame retardant, on the immune response to respiratory syncytial virus infection in mice.","20074668",40]
["Tetracaine","Tetracaine","D013748","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2005,"16219435","Menthol facilitates the skin analgesic effect of tetracaine gel.","16219435",40]
["tetrachloroplatinate","tetrachloroplatinate","C036919","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"11011925","A case of contact hypersensitivity to platinum salts.","11011925",40]
["Tetracycline","Tetracycline","D013752","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4150826","A study of the interaction of tetracycline with human serum lipoproteins and albumin.","4150826",40]
["Tetracycline","Tetracycline","D013752","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1966,"5965438","[Antibiotic-protein interaction as studied by gel filtration].","5965438",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,1,2011,"22189182","Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin.","22189182",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2004,"14623877","12-O-tetradecanoylphorbol-13-acetate and UV radiation-induced nucleoside diphosphate protein kinase B mediates neoplastic transformation of epidermal cells.","14623877",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"22871965","Phorbol esters enhance 1α,25-dihydroxyvitamin D3-regulated 25-hydroxyvitamin D-24-hydroxylase (CYP24A1) gene expression through ERK-mediated phosphorylation of specific protein 3 (Sp3) in Caco-2 cells.","22871965",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8139548","rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells.","8139548",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2001,"11532864","Inhibition of phorbol ester-induced AP-1-DNA binding, c-Jun protein and c-jun mRNA by dietary energy restriction is reversed by adrenalectomy in SENCAR mouse epidermis.","11532864",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1985,"3159344","Enhancement in the activities of mouse epidermal glucose-6-phosphate dehydrogenase, hexokinase, phosphofructokinase, and pyruvate kinase by 12-O-tetradecanoyl-phorbol-13-acetate.","3159344",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1979,"476606","Epidermal prostaglandins after topical application of a tumor promotor.","476606",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2000,"10940935","Requirement for integration of phorbol 12-myristate 13-acetate and calcium pathways is preserved in the transactivation domain of NFAT1.","10940935",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1991,"1830012","Differential modulation of leucocyte surface antigens by various inducers on the T-cell line MOLT-4.","1830012",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1989,"2552994","The phorbol ester TPA stimulates the expression of functional beta-adrenoceptors in human T lymphoblasts Molt 3.","2552994",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1984,"6332252","Influence of PMA on T-lymphocyte responses to mitogenic lymphokines.","6332252",40]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6809817","Independent and synergistic thymocyte proliferative activities of PMA and IL 1.","6809817",40]
["tetrakis(4-chlorophenyl)borate","tetrakis(4-chlorophenyl)borate","C030385","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20735009","Interfacial complexes between a protein and lipophilic ions at an oil-water interface.","20735009",40]
["tetra-N-acetyl-chitotetraosyl allosamizoline","tetra-N-acetyl-chitotetraosyl allosamizoline","C512151","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"17194033","A new fermentation process allows large-scale production of tetra-N-acetyl-chitotetraosyl allosamizoline.","17194033",40]
["tetrazepam","tetrazepam","C005245","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2008,"18973107","Systemic dermatitis due to tetrazepam.","18973107",40]
["tetroxoprim","tetroxoprim","C023507","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1989,"2507751","Effects of tetroxoprim and sulfadiazine on T lymphocyte proliferation and gamma-interferon production.","2507751",40]
["Thalidomide","Thalidomide","D013792","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2008,"18565795","CC-4047 promotes Th1 cell differentiation and reprograms polarized human Th2 cells by enhancing transcription factor T-bet.","18565795",40]
["Thalidomide","Thalidomide","D013792","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2001,"11358558","Successful thalidomide treatment of severe infantile Behçet disease.","11358558",40]
["Thalidomide","Thalidomide","D013792","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2014,"25161268","How does lenalidomide target the chronic lymphocytic leukemia microenvironment?","25161268",40]
["Theobromine","Theobromine","D013805","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9435909","Synthesis and structure-activity relationships of 3,7-dimethyl-1-propargylxanthine derivatives, A2A-selective adenosine receptor antagonists.","9435909",40]
["Theophylline","Theophylline","D013806","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1996,"8842438","Effects of theophylline and rolipram on leukotriene C4 (LTC4) synthesis and chemotaxis of human eosinophils from normal and atopic subjects.","8842438",40]
["Theophylline","Theophylline","D013806","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"2416513","Effectors of rat lung cGMP binding protein-phosphodiesterase.","2416513",40]
["Theophylline","Theophylline","D013806","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1972,"4344086","Effect of cytochalasin B on the response of the chromatophores of isolated frog skin to MSH, theophylline, and dibutyryl cyclic AMP.","4344086",40]
["Theophylline","Theophylline","D013806","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6223412","Suppressor, helper and immunoregulatory T cells in normal human blood as defined by theophylline sensitivity.","6223412",40]
["Thiamine","Thiamine","D013831","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"7433433","[Preparation of thiamine derivative-protein complexes].","7433433",40]
["Thiamine Pyrophosphate","Thiamine Pyrophosphate","D013835","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4593967","Energetic and spectroscopic studies on the interaction between thiamine diphosphate and apotransketolase.","4593967",40]
["thiazolidine-4-carboxylic acid","thiazolidine-4-carboxylic acid","C003438","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1991,"1668705","[Effect of thioproline in vitro on selected functions of peripheral blood lymphocytes from healthy persons and patients with lympho- proliferative syndromes].","1668705",40]
["Thimerosal","Thimerosal","D013849","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1980,"6451153","[A case of allergic drug contact dermatitis].","6451153",40]
["Thioacetazone","Thioacetazone","D013828","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1991,"1708068","Cutaneous sensitivity to thiacetazone.","1708068",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C128195,B128195)","v":"Thioctic Acid"},"Thioctic Acid","D008063","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J128195,K128195)","v":"T-Lymphocytes"},"D013601","T-Lymphocytes",1,3,2010,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q128195,Q128195)","v":"19944706"},"Lipoic acid effects on established atherosclerosis.","19944706",40]
["thioflavin T","thioflavin T","C009462","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16927253","Oligo(ethylene glycol) derivatives of thioflavin T as inhibitors of protein-amyloid interactions.","16927253",40]
["thiolactic acid","thiolactic acid","C023884","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1996,"8833480","Occupational allergic contact dermatitis from thiolactic acid contained in 'ester-free' permanent-waving solutions.","8833480",40]
["Thiopental","Thiopental","D013874","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1970,"5537099","Competition between sulphonamides and thiopental for the binding sites of plasma proteins.","5537099",40]
["Thiophanate","Thiophanate","D013875","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19121585","In vitro study on the interaction between thiophanate methyl and human serum albumin.","19121585",40]
["Thiourea","Thiourea","D013890","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1982,"6802568","Contact allergic reactions to diphenylthiourea and phenylisothiocyanate in PVC adhesive tape.","6802568",40]
["Thiourea","Thiourea","D013890","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22837679","A computational study on thiourea analogs as potent MK-2 inhibitors.","22837679",40]
["Thiourea","Thiourea","D013890","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2009,"19233899","Human mitochondrial thymidine kinase is selectively inhibited by 3'-thiourea derivatives of beta-thymidine: identification of residues crucial for both inhibition and catalytic activity.","19233899",40]
["threitol","threitol","C003460","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"21283989","Preparation, characterisation and entrapment of a non-glycosidic threitol ceramide into liposomes for presentation to invariant natural killer T cells.","21283989",40]
["Thromboxane B2","Thromboxane B2","D013929","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1983,"6600482","Induction of thromboxane release from macrophages by anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72-77.","6600482",40]
["thymostimulin","thymostimulin","C031407","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,1990,"1975746","A double-blind, placebo-controlled trial of thymostimulin in symptomatic HIV-infected patients.","1975746",40]
["thymostimulin","thymostimulin","C031407","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6983936","Effect of red cell transfusions, thymic hormone and deoxycytidine in severe combined immunodeficiency due to adenosine deaminase deficiency.","6983936",40]
["tiliroside","tiliroside","C052083","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20615751","Fluorescence studies of interaction between flavonol p-coumaroylglucoside tiliroside and bovine serum albumin.","20615751",40]
["Timolol","Timolol","D013999","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"14767648","Binding affinity of bunazosin, dorzolamide, and timolol to synthetic melanin.","14767648",40]
["tioconazole","tioconazole","C020527","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1996,"8733370","A study of 72 patients with contact allergy to tioconazole.","8733370",40]
["Tn antigen","Tn antigen","C040286","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"11886825","Novel Tn antigen-containing neoglycopeptides: synthesis and evaluation as anti tumor vaccines.","11886825",40]
["TO-901317","TO-901317","C423915","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2017,"28736297","1α-Hydroxy derivatives of 7-dehydrocholesterol are selective liver X receptor modulators.","28736297",40]
["Tobacco Smoke Pollution","Tobacco Smoke Pollution","D014028","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"27055391","Effect of alpha lipoic acid on smoking-induced skin damage.","27055391",40]
["Tobramycin","Tobramycin","D014031","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6846938","Pulmonary disposition of tobramycin.","6846938",40]
["tocotrienol, delta","tocotrienol, delta","C082097","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22640960","δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells.","22640960",40]
["Tolbutamide","Tolbutamide","D014044","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"894490","Kinetics of drug-drug interactions in sheep: tolbutamide and sulfadimethoxine.","894490",40]
["Tolmetin","Tolmetin","D014046","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2300531","Irreversible binding of tolmetin glucuronic acid esters to albumin in vitro.","2300531",40]
["Toluene","Toluene","D014050","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22414652","Fragrance material review on 2-(p-tolyloxy)ethyl acetate.","22414652",40]
["Toluene 2,4-Diisocyanate","Toluene 2,4-Diisocyanate","D014051","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1982,"6282760","Specific inhibition of contact sensitivity in the guinea pig following tolylene diisocyanate inhalation.","6282760",40]
["Toluene 2,4-Diisocyanate","Toluene 2,4-Diisocyanate","D014051","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1990,"1699434","Bronchial epithelial cells exposed to isocyanates potentiate activation and proliferation of T-cells.","1699434",40]
["TRAM 34","TRAM 34","C411671","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21750563","The KCa3.1 blocker TRAM-34 reduces infarction and neurological deficit in a rat model of ischemia/reperfusion stroke.","21750563",40]
["Tranexamic Acid","Tranexamic Acid","D014148","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23931279","Co-drug strategy for promoting skin targeting and minimizing the transdermal diffusion of hydroquinone and tranexamic acid.","23931279",40]
["traxanox","traxanox","C020178","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"3886506","[Effect of traxanox on antibody formation in C57BL/6 mice].","3886506",40]
["treprostinil","treprostinil","C427248","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22231731","Effect of prostaglandin I2 analogs on cytokine expression in human myeloid dendritic cells via epigenetic regulation.","22231731",40]
["Tretinoin","Tretinoin","D014212","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2015,"25642823","IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.","25642823",40]
["Tretinoin","Tretinoin","D014212","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2007,"17785784","In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid.","17785784",40]
["Tretinoin","Tretinoin","D014212","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2013,"23661510","Vitamin A notches up CD11b hi DC development.","23661510",40]
["Tretinoin","Tretinoin","D014212","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1995,"7720378","Allergic contact dermatitis from retinoic acid.","7720378",40]
["Tretinoin","Tretinoin","D014212","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2001,"11338296","Keratinocyte growth factor expression in human gingival fibroblasts and stimulation of in vitro gene expression by retinoic acid.","11338296",40]
["Tretinoin","Tretinoin","D014212","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2006,"16467112","Chemoprevention of skin carcinogenesis by phenylretinamides: retinoid receptor-independent tumor suppression.","16467112",40]
["Tretinoin","Tretinoin","D014212","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1994,"7881766","Retinoic acid induces expression of PA-FABP (psoriasis-associated fatty acid-binding protein) gene in human skin in vivo but not in cultured skin cells.","7881766",40]
["Tretinoin","Tretinoin","D014212","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,1997,"9444384","Interferon gamma-induced PNA-binding glycoproteins as markers of human keratinocyte differentiation: biological evidence using protein kinase C agonists, antagonists and retinoic acid.","9444384",40]
["Tretinoin","Tretinoin","D014212","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17244680","Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia.","17244680",40]
["Tretinoin","Tretinoin","D014212","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21049972","Structure, energetics, and dynamics of binding coactivator peptide to the human retinoid X receptor α ligand binding domain complex with 9-cis-retinoic acid.","21049972",40]
["Tretinoin","Tretinoin","D014212","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"25248321","All-trans-retinoic acid and CD38 ligation differentially regulate CD1d expression and α-galactosylceramide-induced immune responses.","25248321",40]
["Tretinoin","Tretinoin","D014212","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1975,"130780","Kinetics of epidermis and adnexa following vitamin A acid in the human.","130780",40]
["Tretinoin","Tretinoin","D014212","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"16526558","Enhanced skin regeneration by nanoegg formulation of all-trans retinoic acid.","16526558",40]
["Tretinoin","Tretinoin","D014212","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1988,"3045163","Topical tretinoin in the treatment of aging skin.","3045163",40]
["Tretinoin","Tretinoin","D014212","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1984,"6594079","Pachyonychia congenita. Electron microscopic and epidermal glycoprotein assessment before and during isotretinoin treatment.","6594079",40]
["Tretinoin","Tretinoin","D014212","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9885411","Modulation of human stratum corneum properties by salicylic acid and all-trans-retinoic acid.","9885411",40]
["Tretinoin","Tretinoin","D014212","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2009,"18984738","All-trans retinoic acid inhibits type 1 diabetes by T regulatory (Treg)-dependent suppression of interferon-gamma-producing T-cells without affecting Th17 cells.","18984738",40]
["Tretinoin","Tretinoin","D014212","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"3875405","Potentiation of mitogen-induced human T-lymphocyte activation by retinoic acid.","3875405",40]
["Triamcinolone Acetonide","Triamcinolone Acetonide","D014222","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2006,"16629794","Modulation of the atopy patch test: tacrolimus 0.1% compared with triamcinolone acetonide 0.1%.","16629794",40]
["Triamcinolone Acetonide","Triamcinolone Acetonide","D014222","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,-1,2001,"11703309","Intralesional steroids reduce inflammation from extravasated chemotherapeutic agents.","11703309",40]
["Triamterene","Triamterene","D014223","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1986,"2429018","Effects of standard diuretics and RPH 2823 on transepithelial Na+ transport in isolated frog skin.","2429018",40]
["tribenoside","tribenoside","C100302","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"20118558","The influence of Tribenoside on expression and deposition of epidermal laminins in HaCaT cells.","20118558",40]
["tributyltin","tributyltin","C011559","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"8039543","Effect of tri-n-butyltin on intracellular Ca2+ concentration of mouse thymocytes under Ca(2+)-free condition.","8039543",40]
["Trichloroethylene","Trichloroethylene","D014241","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,-1,2015,"25916453","[The significance of monitoring procalcitonin when applying antibiotics to trichlorethylene dermatitis].","25916453",40]
["trichostatin A","trichostatin A","C012589","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2011,"21421475","[Trichostatin A inhibits the activation of CD(4)(+) T cells by suppressing CD(28) expression in mice].","21421475",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C131907,B131907)","v":"Triclosan"},"Triclosan","D014260","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J131907,K131907)","v":"Dermatitis, Contact"},"D003877","Dermatitis, Contact",0,2,1975,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q131907,Q131907)","v":"1235279"},"Contact sensitivity to Irgasan DP 300.","1235279",40]
["Triclosan","Triclosan","D014260","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1958142","Hand-washing in a neonatal intensive care unit: comparative effectiveness of chlorhexidine gluconate 4% w/v and triclosan 1% w/v.","1958142",40]
["Trifluoroacetic Acid","Trifluoroacetic Acid","D014269","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1446014","Pentahaloethane-based chlorofluorocarbon substitutes and halothane: correlation of in vivo hepatic protein trifluoroacetylation and urinary trifluoroacetic acid excretion with calculated enthalpies of activation.","1446014",40]
["Trifluralin","Trifluralin","D014274","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1998,"9467199","Effect of 2,4-dicholorophenoxyacetic acid, trifluralin and triallate herbicides on immune function.","9467199",40]
["trimellitic anhydride","trimellitic anhydride","C015559","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1998,"9772201","Airway morphology and function of rats following dermal sensitization and respiratory challenge with low molecular weight chemicals.","9772201",40]
["Trimethoprim","Trimethoprim","D014295","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1979,"536341","Tissue penetration of trimethoprim and sulphonamides.","536341",40]
["Trimethoprim, Sulfamethoxazole Drug Combination","Trimethoprim, Sulfamethoxazole Drug Combination","D015662","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2015,"26315539","Proportions of CD4+, CD8+ and B cell subsets are not affected by exposure to HIV or to Cotrimoxazole prophylaxis in Malawian HIV-uninfected but exposed children.","26315539",40]
["Trimethoprim, Sulfamethoxazole Drug Combination","Trimethoprim, Sulfamethoxazole Drug Combination","D015662","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22908161","Has the emergence of community-associated methicillin-resistant Staphylococcus aureus increased trimethoprim-sulfamethoxazole use and resistance?: a 10-year time series analysis.","22908161",40]
["trimethyloxamine","trimethyloxamine","C005855","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27644004","O2 -independent demethylation of trimethylamine N-oxide by Tdm of Methylocella silvestris.","27644004",40]
["Trinitrobenzenesulfonic Acid","Trinitrobenzenesulfonic Acid","D014302","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2007,"17983376","A loose-fit coculture of activated keratinocytes and dendritic cell-related cells for prediction of sensitizing potential.","17983376",40]
["triphenylmethylphosphonium","triphenylmethylphosphonium","C011561","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6466610","Rapid laser flash photoaffinity labeling of binding sites for a noncompetitive inhibitor of the acetylcholine receptor.","6466610",40]
["tripterine","tripterine","C050414","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,1990,"2082679","[Immunosuppressive and antiinflammatory activities of tripterine].","2082679",40]
["trisialoganglioside GT1","trisialoganglioside GT1","C016481","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1992,"1383424","Isolated bovine spinal motoneurons have specific ganglioside antigens recognized by sera from patients with motor neuron disease and motor neuropathy.","1383424",40]
["troclosene","troclosene","C011765","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,2003,"12579187","Sanichlor-induced atopic dermatitis and asthma in ophthalmologists.","12579187",40]
["troglitazone","troglitazone","C057693","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"10671476","Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT.","10671476",40]
["troxacitabine","troxacitabine","C074908","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,1998,"9885404","Beta-L-1,3-dioxolane-cytidine: a novel nucleoside that inhibits proliferation and induces differentiation of keratinocytes in vitro.","9885404",40]
["tubeimoside I","tubeimoside I","C051084","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1994,"8010099","Effects of tubeimoside-1 on HIV core protein p24 and cytopathogenesis in vitro.","8010099",40]
["Tuberculin","Tuberculin","D014373","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,1995,"7621598","Defects in antigen-driven lymphocyte responses in common variable immunodeficiency (CVID) are due to a reduction in the number of antigen-specific CD4+ T cells.","7621598",40]
["Tuberculin","Tuberculin","D014373","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,1970,"5427401","The effect of an exorbitant intracutaneous dose of 200 micrograms PPD tuberculin compared with 0.02 micrograms PPD tuberculin.","5427401",40]
["Tuberculin","Tuberculin","D014373","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1975,"1081859","Local, passive transfer of purified protein derivative-delayed tuberculin hypersensitivity by guinea pig thymus-dependent lymphocytes.","1081859",40]
["Tuberculin","Tuberculin","D014373","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1984,"6421492","Adoptive protection of the Mycobacterium tuberculosis-infected lung. Dissociation between cells that passively transfer protective immunity and those that transfer delayed-type hypersensitivity to tuberculin.","6421492",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C133315,B133315)","v":"Tubocurarine"},"Tubocurarine","D014403","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J133315,K133315)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2011,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q133315,Q133315)","v":"21468359"},"A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors.","21468359",40]
["tungstate","tungstate","C045951","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27498640","QM/MM Analysis of Transition States and Transition State Analogues in Metalloenzymes.","27498640",40]
["Turpentine","Turpentine","D014425","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1977,"606485","Turpentine-induced hypersensitivity to peppermint oil.","606485",40]
["Tylosin","Tylosin","D015645","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1997,"10202771","[Tylosin-specific proliferation in vitro of the peripheral blood mononuclear cells in occupational tylosin allergy].","10202771",40]
["U 65556A","U 65556A","C068246","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2084178","Differential mutagenicity of two dihydrophenalene congeners: examination of formaldehyde generation and reactive intermediate formation as possible mechanisms.","2084178",40]
["Ubiquinone","Ubiquinone","D014451","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17381131","A new ubiquinone metabolite and its activity at the mitochondrial bc1 complex.","17381131",40]
["UHRA-9","UHRA-9","C000595464","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2014,"25202141","Nontoxic polyphosphate inhibitors reduce thrombosis while sparing hemostasis.","25202141",40]
["undecaprenyl pyrophosphate","undecaprenyl pyrophosphate","C088139","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21294851","Applying molecular dynamics simulations to identify rarely sampled ligand-bound conformational states of undecaprenyl pyrophosphate synthase, an antibacterial target.","21294851",40]
["Uracil","Uracil","D014498","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8366081","Dihydropyrimidine dehydrogenase. Kinetic mechanism for reduction of uracil by NADPH.","8366081",40]
["uranium hexafluoride","uranium hexafluoride","C036638","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"16491805","[Quantitative comparison of human percutaneous and inhalational exposures to uranium and fluorine with uranium hexafluoride and its hydrolysis products].","16491805",40]
["Urea","Urea","D014508","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2002,"12081711","Allergic contact dermatitis from urea-formaldehyde resin in medium-density fibreboard (MDF).","12081711",40]
["Urea","Urea","D014508","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15253438","Capillary isoelectric focusing with laser-induced fluorescence whole column imaging detection as a tool to monitor reactions of proteins.","15253438",40]
["Urea","Urea","D014508","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2008,"18365187","SANS/SAXS study of the BSA solvation properties in aqueous urea solutions via a global fit approach.","18365187",40]
["Urea","Urea","D014508","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4136824","Inhibition of guinea-pig complement by derivatives of benzamidine. I. Effect of p-nitrophenylureido derivative of m-(m-phenoxypropoxy)benzamidine on guinea-pig complement component haemolytic activity.","4136824",40]
["Urea","Urea","D014508","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7305338","Interactions of proteins with solvent components in 8 M urea.","7305338",40]
["Urea","Urea","D014508","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2002,"11803256","Do urea/ammonium lactate combinations achieve better skin protection and hydration than either component alone?","11803256",40]
["Uric Acid","Uric Acid","D014527","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1968,"5737250","[Modalities of purine excretion during enzyme treatment of gout and other hyperuricemic conditions with urate oxidase].","5737250",40]
["Uric Acid","Uric Acid","D014527","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2006,"16387838","Uric acid, a nucleic acid degradation product, down-regulates dsRNA-triggered arthritis.","16387838",40]
["Urocanic Acid","Urocanic Acid","D014560","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,1988,"2448393","Cis-urocanic acid, a product formed by ultraviolet B irradiation of the skin, initiates an antigen presentation defect in splenic dendritic cells in vivo.","2448393",40]
["Urocanic Acid","Urocanic Acid","D014560","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"26703629","Protective Effect of Chitin Urocanate Nanofibers against Ultraviolet Radiation.","26703629",40]
["Ursodeoxycholic Acid","Ursodeoxycholic Acid","D014580","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2014,"24265317","Ursodeoxycholic acid inhibits liver X receptor α-mediated hepatic lipogenesis via induction of the nuclear corepressor SMILE.","24265317",40]
["Vaccinium myrtillus extract","Vaccinium myrtillus extract","C073305","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"24397884","Nanoberries for topical delivery of antioxidants.","24397884",40]
["valdecoxib","valdecoxib","C406224","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2006,"16290146","Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II \"selective\" inhibitor celecoxib.","16290146",40]
["Valproic Acid","Valproic Acid","D014635","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1706921","Effect of valproic acid, its unsaturated metabolites and some structurally related fatty acids on the binding of warfarin and dansylsarcosine to human albumin.","1706921",40]
["Valproic Acid","Valproic Acid","D014635","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28120429","Structural insights into human microsomal epoxide hydrolase by combined homology modeling, molecular dynamics simulations, and molecular docking calculations.","28120429",40]
["Valproic Acid","Valproic Acid","D014635","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8440760","Effect of unbound clearance on binding parameters of valproic acid to serum proteins.","8440760",40]
["vandateroside I","vandateroside I","C000608334","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21510636","Glucosyloxybenzyl eucomate derivatives from Vanda teres stimulate HaCaT cytochrome c oxidase.","21510636",40]
["Varenicline","Varenicline","D000068580","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2009,"19489858","Varenicline-induced acute generalized exanthematous pustulosis.","19489858",40]
["vemurafenib","vemurafenib","C551177","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23856932","A STATement on vemurafenib-resistant melanoma.","23856932",40]
["Verapamil","Verapamil","D014700","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2006,"16996495","Verapamil-sensitive Ca2+ channel regulation of Th1-type proliferation of splenic lymphocytes induced by Walker 256 tumor development in rats.","16996495",40]
["Verapamil","Verapamil","D014700","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"7444161","Factors affecting the plasma protein binding of verapamil and norverapamil in man.","7444161",40]
["vesnarinone","vesnarinone","C041667","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2000,"10820260","Vesnarinone suppresses TNF-induced activation of NF-kappa B, c-Jun kinase, and apoptosis.","10820260",40]
["Vinblastine","Vinblastine","D014747","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2002,"12168052","A comparison of human G-Csf and human Gm-Csf given concurrently with anti-cancer chemotherapy.","12168052",40]
["Vincamine","Vincamine","D014749","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1981,"6454536","Contact sensitivity to vincamine tartrate.","6454536",40]
["Vincristine","Vincristine","D014750","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1992,"1398275","Functional depletion of T cells by vincristine and methylprednisolone as an in vitro model for the prevention of graft versus host disease.","1398275",40]
["Vitallium","Vitallium","D014800","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1980,"7418401","Generalized dermatitis from an osteosynthesis screw.","7418401",40]
["Vitamin A","Vitamin A","D014801","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2011,"21220692","Expression of retinaldehyde dehydrogenase enzymes in mucosal dendritic cells and gut-draining lymph node stromal cells is controlled by dietary vitamin A.","21220692",40]
["Vitamin A","Vitamin A","D014801","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1986,"2937294","Hepatic and dermatologic manifestations of chronic hypervitaminosis A in adults. Report of two cases.","2937294",40]
["Vitamin A","Vitamin A","D014801","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1764110","Elevated levels of all-trans-retinoic acid in cultured rat embryos 1.5 hr after intraamniotic microinjections with 13-cis-retinoic acid or retinol and correlations with dysmorphogenesis.","1764110",40]
["Vitamin A","Vitamin A","D014801","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"406937","Vitamin A receptors. I. Comparison of retinol binding to serum retinol-binding protein and to tissue receptors in chick retina and pigment epithelium.","406937",40]
["Vitamin A","Vitamin A","D014801","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8631836","Vitamin A2 bound to cellular retinol-binding protein as ultraviolet filter in the eye lens of the gecko Lygodactylus picturatus.","8631836",40]
["Vitamin A","Vitamin A","D014801","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1955,"13248820","The influence of vitamin A on the epidermis.","13248820",40]
["Vitamin A","Vitamin A","D014801","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1988,"3224346","Pharmacokinetics and metabolism of retinol administered at a chemopreventive level to normal subjects.","3224346",40]
["Vitamin A","Vitamin A","D014801","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2002,"11989744","Effect of dietary supplemental levels of vitamin A on the egg production and immune responses of heat-stressed laying hens.","11989744",40]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1970,"5460679","Immunological properties of human vitamin B 12 binders.","5460679",40]
["Vitamin B 12","Vitamin B 12","D014805","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20014271","Structure and binding of peptide-dendrimer ligands to vitamin B12.","20014271",40]
["Vitamin B 12","Vitamin B 12","D014805","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27638883","Molecular basis of cobalamin-dependent RNA modification.","27638883",40]
["Vitamin B 12","Vitamin B 12","D014805","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1968,"4179186","Serum vitamin B12 binding capacity in patients with anaemia.","4179186",40]
["Vitamin B 12","Vitamin B 12","D014805","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1969,"4977430","Plasma clearance of heated serum bound Co57-vitamin B12.","4977430",40]
["Vitamin B 12","Vitamin B 12","D014805","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1971,"5137036","[Transcobalamines and R-type B 12 -binders].","5137036",40]
["Vitamin B 12","Vitamin B 12","D014805","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"8273984","Omeprazole therapy causes malabsorption of cyanocobalamin (vitamin B12)","8273984",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C136835,B136835)","v":"Vitamin B 12"},"Vitamin B 12","D014805","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J136835,K136835)","v":"T-Lymphocytes"},"D013601","T-Lymphocytes",1,3,2007,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q136835,Q136835)","v":"17548438"},"Synergy between paclitaxel plus an exogenous methyl donor in the suppression of murine demyelinating diseases.","17548438",40]
["Vitamin D","Vitamin D","D014807","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2016,"26369615","Species-specific regulation of innate immunity by vitamin D signaling.","26369615",40]
["Vitamin D","Vitamin D","D014807","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,2016,"27014952","Vitamin D in atopic dermatitis, chronic urticaria and allergic contact dermatitis.","27014952",40]
["Vitamin D","Vitamin D","D014807","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2000,"10726977","Different vitamin D analogues induce sphingomyelin hydrolysis and apoptosis in the human keratinocyte cell line HaCaT.","10726977",40]
["Vitamin D","Vitamin D","D014807","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17693608","Co-chaperone potentiation of vitamin D receptor-mediated transactivation: a role for Bcl2-associated athanogene-1 as an intracellular-binding protein for 1,25-dihydroxyvitamin D3.","17693608",40]
["Vitamin D","Vitamin D","D014807","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24139874","Multifunctional and potent roles of the 3-hydroxypropoxy group provide eldecalcitol's benefit in osteoporosis treatment.","24139874",40]
["Vitamin D","Vitamin D","D014807","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"9891040","Selective interaction of vitamin D receptor with transcriptional coactivators by a vitamin D analog.","9891040",40]
["Vitamin D","Vitamin D","D014807","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2004,"15294940","A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development.","15294940",40]
["Vitamin D","Vitamin D","D014807","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2012,"22085500","Vitamin D, multiple sclerosis and inflammatory bowel disease.","22085500",40]
["Vitamin E","Vitamin E","D014810","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2006,"17181943","[Effects of TCE and PCE on cultured human keratinocyte lipid peroxidation and protective effect of vitamin E on it].","17181943",40]
["Vitamin E","Vitamin E","D014810","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1977,"836040","Studies on the binding of d-alpha-tocopherol to rat liver nuclei.","836040",40]
["Vitamin E","Vitamin E","D014810","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1990,"2111403","Prevention of experimental cancer and immunostimulation by vitamin E (immunosurveillance).","2111403",40]
["Vitamin K","Vitamin K","D014812","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1970,"5439310","Immunochemical measurement of vitamin K-induced biosynthesis of prothrombin in the isolated perfused rat liver.","5439310",40]
["Vitamin K","Vitamin K","D014812","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11988107","Characteristics and composition of the vitamin K-dependent gamma-glutamyl carboxylase-binding domain on osteocalcin.","11988107",40]
["Vitamin K 3","Vitamin K 3","D024483","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2006,"16516204","Activation of ErbB2 by 2-methyl-1,4-naphthoquinone (menadione) in human keratinocytes: role of EGFR and protein tyrosine phosphatases.","16516204",40]
["Voriconazole","Voriconazole","D065819","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2017,"27373453","Voriconazole exposure regulates distinct cell-cycle and terminal differentiation pathways in primary human keratinocytes.","27373453",40]
["VX","VX","C009680","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1995,"7589933","An explanation on the limited efficacy of detoxication against VX toxicity by purified specific antibodies.","7589933",40]
["waglerin","waglerin","C077895","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12069578","Residues in the epsilon subunit of the nicotinic acetylcholine receptor interact to confer selectivity of waglerin-1 for the alpha-epsilon subunit interface site.","12069578",40]
["Warfarin","Warfarin","D014859","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1975,"1197921","Effect of plasma protein binding on the anticoagulant action of warfarin in rats.","1197921",40]
["Warfarin","Warfarin","D014859","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28674307","Effects of Teicoplanin on the PT-INR Controlled by Warfarin in Infection Patients.","28674307",40]
["Warfarin","Warfarin","D014859","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1979,"481132","Differences in the protein binding of several drugs and bilirubin in serum and heparinized plasma of rats.","481132",40]
["Warfarin","Warfarin","D014859","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8305289","Warfarin metabolites: stereochemical aspects of protein binding and displacement by phenylbutazone.","8305289",40]
["Warfarin","Warfarin","D014859","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2004,"15327512","Warfarin-induced skin necrosis.","15327512",40]
["Waste Water","Waste Water","D062065","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2015,"25723343","Colour changes in Labeo rohita (Ham.) due to pigment translocation in melanophores, on exposure to municipal wastewater of Tung Dhab drain, Amritsar, India.","25723343",40]
["Water","Water","D014867","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2017,"28936777","Phytosphingosine enhances moisture level in human skin barrier through stimulation of the filaggrin biosynthesis and degradation leading to NMF formation.","28936777",40]
["Water","Water","D014867","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12036370","NMR-Based screening with competition water-ligand observed via gradient spectroscopy experiments: detection of high-affinity ligands.","12036370",40]
["Water","Water","D014867","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15600083","Pure shear horizontal SAW biosensor on langasite.","15600083",40]
["Water","Water","D014867","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16828799","Sequestered water and binding energy are coupled in complexes of lambda Cro repressor with non-consensus binding sequences.","16828799",40]
["Water","Water","D014867","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20600625","Displacement of disordered water molecules from hydrophobic pocket creates enthalpic signature: binding of phosphonamidate to the S₁'-pocket of thermolysin.","20600625",40]
["Water","Water","D014867","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"27339138","Dynamics and mechanism of ultrafast water-protein interactions.","27339138",40]
["Water","Water","D014867","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22924639","Modeling the self-assembly of peptide amphiphiles into fibers using coarse-grained molecular dynamics.","22924639",40]
["Water","Water","D014867","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26803501","Molecular interactions of the γ-clade homeodomain-leucine zipper class I transcription factors during the wheat response to water deficit.","26803501",40]
["Water","Water","D014867","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27936493","New additions to the ClusPro server motivated by CAPRI.","27936493",40]
["Water","Water","D014867","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1975,"1148274","The mechanical properties of stratum corneum. I. The effect of water and ambient temperature on the tensile properties of newborn rat stratum corneum.","1148274",40]
["Water","Water","D014867","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"19146603","Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study.","19146603",40]
["Water","Water","D014867","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"26616204","Water resistance profile as a marker of skin barrier damage in atopic dermatitis patients.","26616204",40]
["Win 55212-2","Win 55212-2","C070417","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"16849427","The cannabinoid WIN 55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurin.","16849427",40]
["wogonin","wogonin","C085514","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15043845","Binding of wogonin to human serum albumin: a common binding site of wogonin in subdomain IIA.","15043845",40]
["xinfeng","xinfeng","C533622","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"25790670","[Exploration of the mechanism of xinfeng capsule in the treatment of ankylosing spondylitis based on B and T lymphocyte attenuator and oxidative stress].","25790670",40]
["Xylitol","Xylitol","D014993","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21569743","Antiirritant properties of polyols and amino acids.","21569743",40]
["Xylose","Xylose","D014994","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17933895","Regulation of D-xylose metabolism in Caulobacter crescentus by a LacI-type repressor.","17933895",40]
["Yellow Fever Vaccine","Yellow Fever Vaccine","D022341","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2007,"17255244","Innate immune responses in human dendritic cells upon infection by chimeric yellow-fever dengue vaccine serotypes 1-4.","17255244",40]
["Yi-Gan San","Yi-Gan San","C524644","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"19913081","Partial agonistic effect of yokukansan on human recombinant serotonin 1A receptors expressed in the membranes of Chinese hamster ovary cells.","19913081",40]
["Zeranol","Zeranol","D015029","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17097287","Characterization of the estrogenic activities of zearalenone and zeranol in vivo and in vitro.","17097287",40]
["ziconotide","ziconotide","C078452","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10694509","Binding of six chimeric analogs of omega-conotoxin MVIIA and MVIIC to N- and P/Q-type calcium channels.","10694509",40]
["ziconotide","ziconotide","C078452","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10938268","Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes.","10938268",40]
["ziconotide","ziconotide","C078452","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1994,"8087420","Characterization of the binding of omega-conopeptides to different classes of non-L-type neuronal calcium channels.","8087420",40]
["ziconotide","ziconotide","C078452","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1998,"9727385","A-53930A and B, novel N-type Ca2+ channel blockers.","9727385",40]
["ZIK 1392","ZIK 1392","C035836","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1982,"6755244","[Experimental finding with a new type of fungicide].","6755244",40]
["zileuton","zileuton","C063449","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2001,"11694324","Leukotrienes play protective roles early during experimental VSV encephalitis.","11694324",40]
["zileuton","zileuton","C063449","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8213344","The properties of A-69412: a small hydrophilic 5-lipoxygenase inhibitor.","8213344",40]
["zileuton","zileuton","C063449","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1995,"8620669","In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite.","8620669",40]
["zileuton","zileuton","C063449","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"8620671","The effect of mild or moderate hepatic impairment (cirrhosis) on the pharmacokinetics of zileuton.","8620671",40]
["zileuton","zileuton","C063449","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"8620676","The pharmacokinetics of single oral doses of zileuton 200 to 800mg, its enantiomers, and its metabolites, in normal healthy volunteers.","8620676",40]
["zileuton","zileuton","C063449","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2002,"11805220","Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase II: in vivo studies.","11805220",40]
["zileuton","zileuton","C063449","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1998,"9865762","In vivo correlation of neutrophil receptor expression, ischemia-reperfusion injury, and selective 5-lipoxygenase inhibition in guinea pigs.","9865762",40]
["zileuton","zileuton","C063449","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2001,"11527251","Zileuton and atopic dermatitis.","11527251",40]
["zileuton","zileuton","C063449","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1991,"1995987","From the National Institutes of Health.","1995987",40]
["zileuton","zileuton","C063449","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2013,"24021192","Effects of zileuton on airway smooth muscle remodeling after repeated allergen challenge in brown Norway rats.","24021192",40]
["Zimeldine","Zimeldine","D015031","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1982,"6460587","Zimelidine and norzimelidine protein binding measured by equilibrium dialysis and cerebrospinal fluid.","6460587",40]
["Zimeldine","Zimeldine","D015031","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1989,"2530181","Popliteal lymph node reactions in mice induced by the drug zimeldine.","2530181",40]
["zinc 1,4,8,11,15,18,22,25-octa-n-butoxyphthalocyanine","zinc 1,4,8,11,15,18,22,25-octa-n-butoxyphthalocyanine","C061188","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8980387","Tumour-localising and -photosensitising properties of a novel zinc(II) octadecylphthalocyanine.","8980387",40]
["Zinc Acetate","Zinc Acetate","D019345","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1991,"1839272","Contact allergy to di-isopropyl sebacate in Zineryt lotion.","1839272",40]
["Zinc Acetate","Zinc Acetate","D019345","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1986,"2946543","Allergic contact dermatitis due to diisopropyl sebacate.","2946543",40]
["Zinc Acetate","Zinc Acetate","D019345","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1991,"1839272","Contact allergy to di-isopropyl sebacate in Zineryt lotion.","1839272",40]
["Zinc Acetate","Zinc Acetate","D019345","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28900091","[Secondary Structure of Aβ(1-16) Complexes with Zinc: A Study in the Gas Phase Using Deuterium/Hydrogen Exchange and Ultra-High-Resolution Mass Spectrometry].","28900091",40]
["Zinc Acetate","Zinc Acetate","D019345","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1993,"8374604","Immunolocalization of metallothionein (MT), and X.R.M.A. localization of zinc in hamster skin.","8374604",40]
["Zinc Acetate","Zinc Acetate","D019345","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2001,"11695361","Effect of oral zinc supplementation upon Taenia crassiceps murine cysticercosis.","11695361",40]
["zinc chelate-sepharose","zinc chelate-sepharose","C030523","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1714749","Zinc chelates bind human hemopexin.","1714749",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2006,"16426290","Allergenicity and cross-reactivity of naphthenic acid and its metallic salts in experimental animals.","16426290",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,1,2010,"20557345","Generalized exacerbation of systemic allergic dermatitis due to zinc patch test and dental treatments.","20557345",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1996,"8981023","Nickel chloride/chlorides of divalent metal interactions in nickel-sensitive subjects.","8981023",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1997,"9145275","Lymphocytoma cutis involving the lower lip.","9145275",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1958,"13618083","[Dermatoses caused by zinc chloride].","13618083",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,1,2010,"20557345","Generalized exacerbation of systemic allergic dermatitis due to zinc patch test and dental treatments.","20557345",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,1982,"6981341","Zinc and T-lymphocyte function in hemodialysis patients.","6981341",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1993,"8427819","In vitro lymphocyte reactivity to heavy metal salts in the diagnosis of oral mucosal hypersensitivity to amalgam restorations.","8427819",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1588311","Purification and characterization of pyruvate decarboxylase from Sarcina ventriculi.","1588311",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15953358","Opposite effects of Zn on the in vitro binding of [3H]LY354740 to recombinant and native metabotropic glutamate 2 and 3 receptors.","15953358",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1992,"1644799","Properties of the reaction of cis-dichlorodiammineplatinum(II) with metallothionein.","1644799",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"18951909","Allosteric modulation of 5-HT(1A) receptors by zinc: Binding studies.","18951909",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19928950","Rapid and reversible inhibition of aquaporin-4 by zinc.","19928950",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"20413590","Zinc modulates the interaction of protein C and activated protein C with endothelial cell protein C receptor.","20413590",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20664913","Zinc ions bind to and inhibit activated protein C.","20664913",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2226843","Synergy between zinc and phorbol ester in translocation of protein kinase C to cytoskeleton.","2226843",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23335960","G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.","23335960",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3017409","Binding of coagulation factor XI to washed human platelets.","3017409",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3258866","Zinc can increase the activity of protein kinase C and contributes to its binding to plasma membranes in T lymphocytes.","3258866",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8434938","The binding of terbium ions to tubulin induces ring formation.","8434938",40]
["zinc chloride","zinc chloride","C016837","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9062956","Effect of divalent metal ions on the binding of tissue factor and activated factor VII.","9062956",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1999306","Interspecies variations in response to topical application of selected zinc compounds.","1999306",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"24175872","A review of topical corrosive black salve.","24175872",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1993,"7688532","Effect of zinc supplementation on resistance of cultured human skin fibroblasts toward oxidant stress.","7688532",40]
["zinc chloride","zinc chloride","C016837","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1993,"8248330","Protective effect of selenium and zinc on UV-A damage in human skin fibroblasts.","8248330",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1992,"1372657","Cl- channels in intact human T lymphocytes.","1372657",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2008,"18468760","Imidazole antifungals, but not triazole antifungals, increase membrane Zn2+ permeability in rat thymocytes Possible contribution to their cytotoxicity.","18468760",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2010,"20079827","Zinc at clinically-relevant concentrations potentiates the cytotoxicity of polysorbate 80, a non-ionic surfactant.","20079827",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1989,"2566603","Interaction of histidine-rich glycoprotein with human T lymphocytes.","2566603",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1988,"3258866","Zinc can increase the activity of protein kinase C and contributes to its binding to plasma membranes in T lymphocytes.","3258866",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"3873627","Effect of methionine-enkephalin plus ZnCl2 on active T cell rosettes.","3873627",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1985,"3874832","Stimulating effect of zinc chloride on DNA synthesis of human thymocytes.","3874832",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1984,"6334561","Modulatory effect of zinc on the proliferative response of murine spleen cells to polyclonal T cell mitogens.","6334561",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1983,"6604771","Alterations in human natural killer cell activity and monocyte cytotoxicity induced by zinc deficiency.","6604771",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6981341","Zinc and T-lymphocyte function in hemodialysis patients.","6981341",40]
["zinc chloride","zinc chloride","C016837","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1982,"6983115","Development of a serum-free defined culture medium for lymphoblast transformation tests of mouse spleen and thymus cells.","6983115",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C139907,B139907)","v":"zinc chlorin"},"zinc chlorin","C558702","1_MIE",396,1,"Protein","Covalent Binding",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J139907,K139907)","v":"Protein Binding"},"D011485","Protein Binding",1,1,2013,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q139907,Q139907)","v":"23935866"},"Factors controlling the redox potential of ZnCe6 in an engineered bacterioferritin photochemical 'reaction centre'.","23935866",40]
["zinc chromate","zinc chromate","C023616","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"2973393","Irritant contact dermatitis and chrome-passivated metal.","2973393",40]
["zinc dibenzyldithiocarbamate","zinc dibenzyldithiocarbamate","C005895","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"10908178","Allergic contact dermatitis to socks presenting as bleached rubber syndrome.","10908178",40]
["zinc dibenzyldithiocarbamate","zinc dibenzyldithiocarbamate","C005895","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"12786726","Patch testing with zinc dibenzyldithiocarbamate. A multicentre study of the Information Network of Departments of Dermatology and the German Contact Dermatitis Research Group.","12786726",40]
["zinc dibutyldithiocarbamate","zinc dibutyldithiocarbamate","C017801","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"8654121","Allergic reaction to nonrubber products by testing with rubber mixes. Part IV: the carba mix.","8654121",40]
["zinc fluoride","zinc fluoride","C038904","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22283393","Two ZnF-UBP domains in isopeptidase T (USP5).","22283393",40]
["zinc hematoporphyrin","zinc hematoporphyrin","C017802","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21882349","Z-DNA recognition in B-Z-B sequences by a cationic zinc porphyrin.","21882349",40]
["zinc hydroxide","zinc hydroxide","C052745","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"7901850","Structural analysis of the zinc hydroxide-Thr-199-Glu-106 hydrogen-bond network in human carbonic anhydrase II.","7901850",40]
["zinc mesoporphyrin","zinc mesoporphyrin","C058069","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18325350","Zinc mesoporphyrin induces rapid and marked degradation of the transcription factor Bach1 and up-regulates HO-1.","18325350",40]
["Zinc Oxide","Zinc Oxide","D015034","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2016,"27887623","Generation of protective immunity against Orientia tsutsugamushi infection by immunization with a zinc oxide nanoparticle combined with ScaA antigen.","27887623",40]
["Zinc Oxide","Zinc Oxide","D015034","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2016,"27887623","Generation of protective immunity against Orientia tsutsugamushi infection by immunization with a zinc oxide nanoparticle combined with ScaA antigen.","27887623",40]
["Zinc Oxide","Zinc Oxide","D015034","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"21656222","Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles.","21656222",40]
["Zinc Oxide","Zinc Oxide","D015034","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2012,"22842014","Effects of subtoxic concentrations of TiO2 and ZnO nanoparticles on human lymphocytes, dendritic cells and exosome production.","22842014",40]
["Zinc Oxide","Zinc Oxide","D015034","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2012,"22901679","Effects of flame made zinc oxide particles in human lung cells - a comparison of aerosol and suspension exposures.","22901679",40]
["Zinc Oxide","Zinc Oxide","D015034","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2013,"23894303","Gene expression profiling of immune-competent human cells exposed to engineered zinc oxide or titanium dioxide nanoparticles.","23894303",40]
["Zinc Oxide","Zinc Oxide","D015034","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2016,"27887623","Generation of protective immunity against Orientia tsutsugamushi infection by immunization with a zinc oxide nanoparticle combined with ScaA antigen.","27887623",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1995,"8706397","Rosin (colophony) and zinc oxide in adhesive bandages. An appropriate combination for rosin-sensitive patients?","8706397",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,2014,"25123235","Topically applied ZnO nanoparticles suppress allergen induced skin inflammation but induce vigorous IgE production in the atopic dermatitis mouse model.","25123235",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1990,"2096023","Inhibitory effect of zinc oxide on contact allergy due to colophony.","2096023",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1974,"4617689","On 8-hydroxyquinoline-zinc oxide incompatibility.","4617689",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1982,"7140266","Cross sensitivity between zinc oxide plaster and Cupressus leylandii shrubs.","7140266",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1990,"2141112","Paste bandages for leg ulcers.","2141112",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1988,"2971581","[The effectiveness of prednisolone in zinc oxide containing ointments].","2971581",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1995,"7763227","Probable chloracne with the use of a cow udder ointment.","7763227",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2001,"11573228","Skin protection for photosensitized patients.","11573228",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2001,"11705727","The relationship between UVB screening and cytoprotection by microcorpuscular ZnO or ascorbate against DNA photodamage and membrane injuries in keratinocytes by oxidative stress.","11705727",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"20677183","Toxicological aspects of long-term treatment of keratinocytes with ZnO and TiO2 nanoparticles.","20677183",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2010,"21122045","UV irradiation-induced zinc dissociation from commercial zinc oxide sunscreen and its action in human epidermal keratinocytes.","21122045",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21780369","Zinc oxide nanoparticle induced genotoxicity in primary human epidermal keratinocytes.","21780369",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23270955","Investigation of the photocatalytic effect of zinc oxide nanoparticles in the presence of nitrite.","23270955",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23862422","Phototoxicity of zinc oxide nanoparticles in HaCaT keratinocytes-generation of oxidative DNA damage during UVA and visible light irradiation.","23862422",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"24001789","ZnO nanoparticles induce TNF-α expression via ROS-ERK-Egr-1 pathway in human keratinocytes.","24001789",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2014,"24750048","Yashada bhasma (Zinc calx) and Tankana (Borax) inhibit Propionibacterium acne and suppresses acne induced inflammation in vitro.","24750048",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"27542711","UVB irradiation-enhanced zinc oxide nanoparticles-induced DNA damage and cell death in mouse skin.","27542711",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"27570453","Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes.","27570453",40]
["Zinc Oxide","Zinc Oxide","D015034","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"27693632","Comparative analysis of the relative potential of silver, Zinc-oxide and titanium-dioxide nanoparticles against UVB-induced DNA damage for the prevention of skin carcinogenesis.","27693632",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15236241","Identification and characterization of Cu(2)O- and ZnO-binding polypeptides by Escherichia coli cell surface display: toward an understanding of metal oxide binding.","15236241",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16581242","Morphological and binding properties of interleukin-6 on thin ZnO films grown on (100) silicon substrates for biosensor applications.","16581242",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18039464","Grafting of material-binding function into antibodies Functionalization by peptide grafting.","18039464",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19400578","Protective antigen detection using horizontally stacked hexagonal ZnO platelets.","19400578",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20000396","Direct and selective immobilization of proteins by means of an inorganic material-binding peptide: discussion on functionalization in the elongation to material-binding peptide.","20000396",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20026000","Screening of peptides with a high affinity for ZnO using spot-synthesized peptide arrays and computational analysis.","20026000",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20499830","Interaction of MnO and ZnO nanomaterials with biomedically important proteins and cells.","20499830",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20506179","Peptide array-based characterization and design of ZnO-high affinity peptides.","20506179",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2010,"20708676","Zinc oxide nanoparticle disruption of store-operated calcium entry in a muscarinic receptor signaling pathway.","20708676",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20848304","Bio-inorganic synthesis of ZnO powders using recombinant His-tagged ZnO binding peptide as a promoter.","20848304",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"20947422","Material-binding peptide application--ZnO crystal structure control by means of a ZnO-binding peptide.","20947422",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21371570","ZnO-ZnS QDs interfacial heterostructure for drug and food delivery application: enhancement of the binding affinities of flavonoid aglycones to bovine serum albumin.","21371570",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21553287","Targeting and sensing cancer cells with ZnO nanoprobes in vitro.","21553287",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21611669","Effect of ZnO#ZnS QDs heterojunctures on the stilbenes-plasma proteins interactions.","21611669",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23010116","Systematic investigation on the interaction of bovine serum albumin with ZnO nanoparticles using fluorescence spectroscopy.","23010116",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23274157","Interaction of cytochrome c with zinc oxide nanoparticles.","23274157",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2014,"24937133","Bactericidal effect of polyethyleneimine capped ZnO nanoparticles on multiple antibiotic resistant bacteria harboring genes of high-pathogenicity island.","24937133",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"25565839","Analysis of zinc oxide nanoparticles binding proteins in rat blood and brain homogenate.","25565839",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26065816","Green biosynthesis of ZnO nanoparticles using Vitex negundo L. extract: Spectroscopic investigation of interaction between ZnO nanoparticles and human serum albumin.","26065816",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26361274","Low-Index ZnO Crystal Plane-Specific Binding Behavior of Whole Immunoglobulin G Proteins.","26361274",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26364076","Inulin as a novel biocompatible coating: evaluation of surface affinities toward CaHPO4, α-Fe2O3, ZnO, CaHPO4@ZnO and α-Fe2O3@ZnO nanoparticles.","26364076",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27441385","Synergistic toxicity of zno nanoparticles and dimethoate in mice: Enhancing their biodistribution by synergistic binding of serum albumin and dimethoate to zno nanoparticles.","27441385",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"27984146","Deciphering the interaction of bovine heart cystatin with ZnO nanoparticles: Spectroscopic and thermodynamic approach.","27984146",40]
["Zinc Oxide","Zinc Oxide","D015034","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3945970","Effect of intratracheal injection of zinc oxide dust in guinea pigs.","3945970",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1999,"10640841","Efficacy of topical application of eosin compared with zinc oxide paste and corticosteroid cream for diaper dermatitis.","10640841",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2001,"11573228","Skin protection for photosensitized patients.","11573228",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2001,"11705727","The relationship between UVB screening and cytoprotection by microcorpuscular ZnO or ascorbate against DNA photodamage and membrane injuries in keratinocytes by oxidative stress.","11705727",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2004,"15575860","Granular parakeratosis.","15575860",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C139971,B139971)","v":"Zinc Oxide"},"Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J139971,K139971)","v":"Skin"},"D012867","Skin",0,1,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q139971,Q139971)","v":"15807813"},"Skin changes induced by a zinc oxide dressing compared with a hydrocolloid dressing in healthy individuals.","15807813",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2005,"15909441","Comparison of two peri-wound skin protectants in venous leg ulcers: a randomised controlled trial.","15909441",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2009,"19469888","Protective effects of a cream containing Dead Sea minerals against UVB-induced stress in human skin.","19469888",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2009,"19646780","The safety of nanosized particles in titanium dioxide- and zinc oxide-based sunscreens.","19646780",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"20795900","Zinc oxide nanoparticles in modern sunscreens: an analysis of potential exposure and hazard.","20795900",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21642632","Safety evaluation of sunscreen formulations containing titanium dioxide and zinc oxide nanoparticles in UVB sunburned skin: an in vitro and in vivo study.","21642632",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"21830917","Repeated dose dermal toxicity study of nano zinc oxide with Sprague-Dawley rats.","21830917",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22293917","Topical tacrolimus and 50% zinc oxide paste for Hailey-Hailey disease: less is more.","22293917",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22471715","Dermal toxicity of ZnO nanoparticles: a worrying feature of sunscreen?","22471715",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2012,"22975498","Measurement of skin permeation/penetration of nanoparticles for their safety evaluation.","22975498",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23454052","The effect of formulation on the penetration of coated and uncoated zinc oxide nanoparticles into the viable epidermis of human skin in vivo.","23454052",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"24575878","Enhanced sun protection of nano-sized metal oxide particles over conventional metal oxide particles: an in vitro comparative study.","24575878",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"24731914","Development and validation of TOF-SIMS and CLSM imaging method for cytotoxicity study of ZnO nanoparticles in HaCaT cells.","24731914",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"24977261","Penetration, photo-reactivity and photoprotective properties of nanosized ZnO.","24977261",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2014,"25123235","Topically applied ZnO nanoparticles suppress allergen induced skin inflammation but induce vigorous IgE production in the atopic dermatitis mouse model.","25123235",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27102240","Effect of flexing and massage on in vivo human skin penetration and toxicity of zinc oxide nanoparticles.","27102240",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27281296","Engineered Zinc Oxide Nanoparticles; Biological Interactions at the Organ Level.","27281296",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27345703","ZnO nanoparticles and organic chemical UV-filters are equally well tolerated by human immune cells.","27345703",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27542711","UVB irradiation-enhanced zinc oxide nanoparticles-induced DNA damage and cell death in mouse skin.","27542711",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27573548","Use of Agave tequilana-lignin and zinc oxide nanoparticles for skin photoprotection.","27573548",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"28064368","Nanostructured ZnO films on stainless steel are highly safe and effective for antimicrobial applications.","28064368",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"28326861","Cutaneous applied nano-ZnO reduce the ability of hair follicle stem cells to differentiate.","28326861",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1981,"7021745","Subcutaneous implantation for the biological evaluation of endodontic materials.","7021745",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1993,"7654594","Zinc oxide increases degradation of collagen in necrotic wound tissue.","7654594",40]
["Zinc Oxide","Zinc Oxide","D015034","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1994,"7908478","Occlusivity and effects of two occlusive dressings on normal human skin.","7908478",40]
["Zinc Oxide","Zinc Oxide","D015034","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2014,"24757670","Potent anti-inflammatory activity of carbohydrate polymer with oxide of zinc.","24757670",40]
["Zinc Oxide","Zinc Oxide","D015034","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23435881","No protective effects of high-dosage dietary zinc oxide on weaned pigs infected with Salmonella enterica serovar typhimurium DT104.","23435881",40]
["Zinc Oxide","Zinc Oxide","D015034","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2014,"25123235","Topically applied ZnO nanoparticles suppress allergen induced skin inflammation but induce vigorous IgE production in the atopic dermatitis mouse model.","25123235",40]
["Zinc Oxide","Zinc Oxide","D015034","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"25378273","Acute exposure to ZnO nanoparticles induces autophagic immune cell death.","25378273",40]
["Zinc Oxide","Zinc Oxide","D015034","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2017,"28165880","Complete transformation of ZnO and CuO nanoparticles in culture medium and lymphocyte cells during toxicity testing.","28165880",40]
["Zinc Oxide-Eugenol Cement","Zinc Oxide-Eugenol Cement","D015035","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2002,"12353045","Adverse reactions associated with the use of eugenol in dentistry.","12353045",40]
["Zinc Oxide-Eugenol Cement","Zinc Oxide-Eugenol Cement","D015035","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,2017,"27873521","A Case of Recurrent Urticaria Due to Formaldehyde Release from Root-Canal Disinfectant.","27873521",40]
["Zinc Oxide-Eugenol Cement","Zinc Oxide-Eugenol Cement","D015035","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2016,"26960744","Cytotoxicity and anti-inflammatory effects of zinc ions and eugenol during setting of ZOE in immortalized human oral keratinocytes grown as three-dimensional spheroids.","26960744",40]
["Zinc Oxide-Eugenol Cement","Zinc Oxide-Eugenol Cement","D015035","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"17055915","Reactions of connective tissue to amalgam, intermediate restorative material, mineral trioxide aggregate, and mineral trioxide aggregate mixed with chlorhexidine.","17055915",40]
["Zinc Oxide-Eugenol Cement","Zinc Oxide-Eugenol Cement","D015035","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2010,"19775730","Comparision of biocompatibility and cytotoxicity of two new root canal sealers.","19775730",40]
["Zinc Oxide-Eugenol Cement","Zinc Oxide-Eugenol Cement","D015035","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1988,"3163136","A comparative tissue toxicity evaluation of established and newer root canal sealers.","3163136",40]
["Zinc Oxide-Eugenol Cement","Zinc Oxide-Eugenol Cement","D015035","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1986,"3465705","[Methodology of a standard technic for evaluating bone biocompatibility of canal filling materials: II. Histologic results on 2 materials: gutta percha and zinc oxide eugenol].","3465705",40]
["Zinc Oxide-Eugenol Cement","Zinc Oxide-Eugenol Cement","D015035","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1977,"407166","Biologic evaluation of filling materials. A comparison of results using cell culture techniques, implantation tests and pulp studies.","407166",40]
["zinc phosphate","zinc phosphate","C043952","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2016,"26921522","Lipid-enveloped zinc phosphate hybrid nanoparticles for codelivery of H-2K(b) and H-2D(b)-restricted antigenic peptides and monophosphoryl lipid A to induce antitumor immunity against melanoma.","26921522",40]
["zinc phosphate","zinc phosphate","C043952","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2016,"26921522","Lipid-enveloped zinc phosphate hybrid nanoparticles for codelivery of H-2K(b) and H-2D(b)-restricted antigenic peptides and monophosphoryl lipid A to induce antitumor immunity against melanoma.","26921522",40]
["zinc phosphate","zinc phosphate","C043952","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,2017,"28989131","Comparison of Hypersensitivity in Metal Ceramic Crowns cemented with Zinc Phosphate and Self-adhesive Resin: A Prospective Study.","28989131",40]
["Zinc Phosphate Cement","Zinc Phosphate Cement","D015036","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1984,"6598295","[Histologic evaluation of the biologic tolerance of zinc oxyphosphate cement].","6598295",40]
["zinc protoporphyrin","zinc protoporphyrin","C017803","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2012,"22900010","Blockage of heme oxygenase-1 abrogates the protective effect of regulatory T cells on murine pregnancy and promotes the maturation of dendritic cells.","22900010",40]
["zinc protoporphyrin","zinc protoporphyrin","C017803","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11222374","Unique effects of zinc protoporphyrin on HO-1 induction and apoptosis.","11222374",40]
["zinc protoporphyrin","zinc protoporphyrin","C017803","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19100614","Via zinc(II) protoporphyrin to the synthesis of poly(ZnPP-MAA-EGDMA) for the imprinting and selective binding of bilirubin.","19100614",40]
["zinc protoporphyrin","zinc protoporphyrin","C017803","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20491653","In vivo uptake of a haem analogue Zn protoporphyrin IX by the human malaria parasite P. falciparum-infected red blood cells.","20491653",40]
["zinc protoporphyrin","zinc protoporphyrin","C017803","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2719938","Interaction of zinc protoporphyrin with intact oxyhemoglobin.","2719938",40]
["zinc protoporphyrin","zinc protoporphyrin","C017803","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1997,"9395306","Hemin and related porphyrins inhibit beta-amyloid aggregation.","9395306",40]
["zinc selenide","zinc selenide","C044696","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16492023","Size series of small indium arsenide-zinc selenide core-shell nanocrystals and their application to in vivo imaging.","16492023",40]
["zinc selenide","zinc selenide","C044696","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24835726","Fluorescence resonance energy transfer between ZnSe ZnS quantum dots and bovine serum albumin in bioaffinity assays of anticancer drugs.","24835726",40]
["Zinc Sulfate","Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,1,1999,"10344487","ZnSO4 treatment of NiSO4-positive patients.","10344487",40]
["Zinc Sulfate","Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1989,"2620519","Acupuncture needle dermatitis.","2620519",40]
["Zinc Sulfate","Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,-1,1996,"8617190","Effects of short-term zinc supplementation on cellular immunity, respiratory symptoms, and growth of malnourished Equadorian children.","8617190",40]
["Zinc Sulfate","Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1980,"7423143","[The effect of oral zinc sulfate on human immunologic reactivity].","7423143",40]
["Zinc Sulfate","Zinc Sulfate","D019287","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2003,"12624476","Effects of zinc histidine and zinc sulfate on natural human keratinocytes.","12624476",40]
["Zinc Sulfate","Zinc Sulfate","D019287","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2009,"19000913","Zinc regulates the dopamine transporter in a membrane potential and chloride dependent manner.","19000913",40]
["Zinc Sulfate","Zinc Sulfate","D019287","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21611669","Effect of ZnO#ZnS QDs heterojunctures on the stilbenes-plasma proteins interactions.","21611669",40]
["Zinc Sulfate","Zinc Sulfate","D019287","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1982,"7081095","Binding of zinc to casein.","7081095",40]
["Zinc Sulfate","Zinc Sulfate","D019287","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1994,"7983574","Comparison of the metal-binding anticandidal activities of serum and abscess fluid supernatants.","7983574",40]
["Zinc Sulfate","Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1992,"1447651","Clinical response of alopecia, trichorrhexis nodosa, and dry, scaly skin to zinc supplementation.","1447651",40]
["Zinc Sulfate","Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2006,"16417711","Possible mechanisms of action of the compounds injected intralesionally in the treatment of cutaneous leishmaniasis, in addition to their direct effects on the parasites.","16417711",40]
["Zinc Sulfate","Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1991,"1990212","Enhancement of re-epithelialization with topical zinc oxide in porcine partial-thickness wounds.","1990212",40]
["Zinc Sulfate","Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23896840","Zinc sulphate administered by transdermal iontophoresis improves breaking strength of surgical wounds in skin of alloxan-induced diabetic rats.","23896840",40]
["Zinc Sulfate","Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2017,"27516148","In vitro permeation and biological activity of punicalagin and zinc (II) across skin and mucous membranes prone to Herpes simplex virus infection.","27516148",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C140035,B140035)","v":"Zinc Sulfate"},"Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J140035,K140035)","v":"Skin"},"D012867","Skin",0,1,1983,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q140035,Q140035)","v":"6229814"},"[Zinc in skin diseases].","6229814",40]
["Zinc Sulfate","Zinc Sulfate","D019287","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1997,"9511156","[Morphofunctional changes in animal skin during combined administration of zinc sulfate and vitamin A].","9511156",40]
["Zinc Sulfate","Zinc Sulfate","D019287","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2000,"10965435","Influence of cadmium and zinc sulphates on the function of human T lymphocytes in vitro.","10965435",40]
["Zinc Sulfate","Zinc Sulfate","D019287","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1992,"1293769","[Study on zinc resistance to the immunosuppression caused by cyclophosphamidum in the mouse].","1293769",40]
["Zinc Sulfate","Zinc Sulfate","D019287","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2015,"25803777","Effects of zinc sulfate supplementation on cell-mediated immune response in head and neck cancer patients treated with radiation therapy.","25803777",40]
["Zinc Sulfate","Zinc Sulfate","D019287","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1995,"8528136","DNA fragmentation induced in lymphocytes by gamma irradiation or dexamethasone: inhibition by diethyldithiocarbamate (DTC), potentiated by zinc.","8528136",40]
["zinc sulfide","zinc sulfide","C031238","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23586311","In vitro cytotoxicity of CdSe/ZnS quantum dots with different surface coatings to human keratinocytes HaCaT cells.","23586311",40]
["zinc sulfide","zinc sulfide","C031238","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23620993","Thiol antioxidant-functionalized CdSe/ZnS quantum dots: synthesis, characterization, cytotoxicity.","23620993",40]
["zinc sulfide","zinc sulfide","C031238","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21371570","ZnO-ZnS QDs interfacial heterostructure for drug and food delivery application: enhancement of the binding affinities of flavonoid aglycones to bovine serum albumin.","21371570",40]
["zinc sulfide","zinc sulfide","C031238","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21482179","Synthesis and characterizations of ultra-small ZnS and Zn(1-x)Fe(x)S quantum dots in aqueous media and spectroscopic study of their interactions with bovine serum albumin.","21482179",40]
["zinc sulfide","zinc sulfide","C031238","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2013,"23261560","Self-assembling peptide assemblies bound to ZnS nanoparticles and their interactions with mammalian cells.","23261560",40]
["zinc sulfide","zinc sulfide","C031238","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24835726","Fluorescence resonance energy transfer between ZnSe ZnS quantum dots and bovine serum albumin in bioaffinity assays of anticancer drugs.","24835726",40]
["zinc sulfide","zinc sulfide","C031238","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"22195482","The cytotoxicity of OPA-modified CdSe/ZnS core/shell quantum dots and its modulation by silibinin in human skin cells.","22195482",40]
["zinc tetrasulfophthalocyanine","zinc tetrasulfophthalocyanine","C052735","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21367615","In vitro toxicity testing of zinc tetrasulfophthalocyanines in fibroblast and keratinocyte cells for the treatment of melanoma cancer by photodynamic therapy.","21367615",40]
["zinc tetrasulfophthalocyanine","zinc tetrasulfophthalocyanine","C052735","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"7463038","Metal phthalocyanine substituted hemoglobins. Complexes of manganese and zinc tetrasulfonated phthalocyanines with apohemoglobin.","7463038",40]
["zinc tetrasulfophthalocyanine","zinc tetrasulfophthalocyanine","C052735","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21763732","A delivery system to avoid self-aggregation and to improve in vitro and in vivo skin delivery of a phthalocyanine derivative used in the photodynamic therapy.","21763732",40]
["ZINC12296427","ZINC12296427","C000612159","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26959013","Computational Study on New Natural Compound Inhibitors of Pyruvate Dehydrogenase Kinases.","26959013",40]
["ZINC12389251","ZINC12389251","C000612160","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26959013","Computational Study on New Natural Compound Inhibitors of Pyruvate Dehydrogenase Kinases.","26959013",40]
["ZINC13451138","ZINC13451138","C574249","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22405030","Potential selective inhibitors against Rv0183 of Mycobacterium tuberculosis targeting host lipid metabolism.","22405030",40]
["Zineb","Zineb","D015038","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"11016679","Contact allergy due to propineb.","11016679",40]
["Zineb","Zineb","D015038","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,1997,"9034689","Allergic contact dermatitis from the fungicide Rondo-M and the insecticide Alfacron.","9034689",40]
["Zineb","Zineb","D015038","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,3,1980,"6448120","Cutaneous allergic reactions to dithiocarbamates.","6448120",40]
["Zineb","Zineb","D015038","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1985,"3160613","[Dimethoate and dithiocarbamate as occupational contact allergens in a female agrotechnician].","3160613",40]
["Zineb","Zineb","D015038","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1983,"6861483","Allergic contact dermatitis from ethylene thiourea.","6861483",40]
["Zineb","Zineb","D015038","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1976,"977138","Experimental study on contact dermatitis caused by dithiocarbamates maneb, mancozeb, zineb, and their related compounds.","977138",40]
["Zineb","Zineb","D015038","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21375462","Neoplastic alterations induced in mammalian skin following mancozeb exposure using in vivo and in vitro models.","21375462",40]
["Zineb","Zineb","D015038","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1997,"9418944","Studies on rat thyroid after oral administration of mancozeb: morphological and biochemical evaluations.","9418944",40]
["Zineb","Zineb","D015038","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1992,"1733566","Status of ornithine decarboxylase activity and DNA synthesis in mancozeb-exposed mouse skin.","1733566",40]
["Zineb","Zineb","D015038","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21375462","Neoplastic alterations induced in mammalian skin following mancozeb exposure using in vivo and in vitro models.","21375462",40]
["Zineb","Zineb","D015038","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1987,"3652029","Tumour initiating activity of mancozeb--a carbamate fungicide in mouse skin.","3652029",40]
["Zineb","Zineb","D015038","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2002,"12211077","Effect of dithiocarbamate pesticide zineb and its commercial formulation, azzurro. II. micronucleus induction in immunophenotyped human lymphocytes.","12211077",40]
["Zineb","Zineb","D015038","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2016,"26796295","Exposure to cypermethrin and mancozeb alters the expression profile of THBS1, SPP1, FEZ1 and GPNMB in human peripheral blood mononuclear cells.","26796295",40]
["zingerone","zingerone","C013738","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2017,"29117507","Zingerone protects keratinocyte stem cells from UVB-induced damage.","29117507",40]
["Zinostatin","Zinostatin","D009353","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1976,"63321","Radioimmunoassay of neocarzinostatin, an antitumor protein.","63321",40]
["Zinostatin","Zinostatin","D009353","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1996,"8606548","Applicability of monoclonal antibody Fab fragments as a carrier of neocarzinostatin in targeting chemotherapy.","8606548",40]
["Zinostatin","Zinostatin","D009353","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,1976,"141012","Neocarzinostatin (NSC 157365) a new cancerostatic compound.","141012",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11983081","Design, production, and characterization of recombinant neocarzinostatin apoprotein in Escherichia coli.","11983081",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15169956","Affinity transfer by CDR grafting on a nonimmunoglobulin scaffold.","15169956",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16529771","Structures of in vitro evolved binding sites on neocarzinostatin scaffold reveal unanticipated evolutionary pathways.","16529771",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16568976","Synthetic ligands for apo-neocarzinostatin.","16568976",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16651736","Preparation of neocarzinostatin apoprotein mutants and the randomized library on the chromophore-binding cavity.","16651736",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1828722","Neocarzinostatin: selective tryptophan oxidation and neocarzinostatin-chromophore binding to apo-neocarzinostatin.","1828722",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18624396","Influence of conformational flexibility on complexation-induced changes in chemical shift in a neocarzinostatin protein-ligand complex.","18624396",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19415706","Disulfide bond substitution by directed evolution in an engineered binding protein.","19415706",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19702337","Molecular basis of substrate promiscuity for the SAM-dependent O-methyltransferase NcsB1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.","19702337",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21268152","Role of steric effects in protein-directed enediyne cycloaromatization of neocarzinostatin.","21268152",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23322746","Evaluating the use of Apo-neocarzinostatin as a cell penetrating protein.","23322746",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2016,"26642954","Probing the biophysical interaction between Neocarzinostatin toxin and EpCAM RNA aptamer.","26642954",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"2961908","Facilitated internalization of neocarzinostatin and its lipophilic polymer conjugate, SMANCS, into cytosol in acidic pH.","2961908",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1974,"4282218","Structure of the antitumor protein neocarzinostatin. Purification, amino acid composition, disulfide reduction, and isolation and composition of tryptic peptides.","4282218",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"6444949","Reversible modification of arginine residues in neocarzinostatin. Isolation of a biologically active 89-residue fragment from the tryptic hydrolysate.","6444949",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"6445749","Effect of nonprotein chromophore removal on neocarzinostatin action.","6445749",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"6446321","A model for the activation and inactivation of neocarzinostatin, an antitumor protein.","6446321",40]
["Zinostatin","Zinostatin","D009353","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"6452126","Neocarzinostatin: controlled release of chromophore and its interaction with DNA.","6452126",40]
["Zinostatin","Zinostatin","D009353","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1989,"2522915","Skin fibroblasts from patients with the genetic disorder hereditary hemorrhagic telangiectasia compared with ataxia-telangiectasia fibroblasts in their response to the radiomimetic drug neocarzinostatin.","2522915",40]
["Zinostatin","Zinostatin","D009353","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1983,"6220700","Repair of potentially lethal and sublethal damage induced by neocarzinostatin in normal and ataxia-telangiectasia skin fibroblasts.","6220700",40]
["Zinostatin","Zinostatin","D009353","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1983,"6223717","Induction and repair of DNA damage in normal and ataxia-telangiectasia skin fibroblasts treated with neocarzinostatin.","6223717",40]
["Zinostatin","Zinostatin","D009353","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1988,"2451896","Interferon induction by SMANCS: a polymer-conjugated derivative of neocarzinostatin.","2451896",40]
["Zinostatin","Zinostatin","D009353","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1989,"2521660","In vitro manipulation of human anti-DNA antibody production by anti-idiotypic antibodies conjugated with neocarzinostatin.","2521660",40]
["Zinostatin","Zinostatin","D009353","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1996,"8620506","Changes in cellular components of spleen and lymph node cells and the effector cells responsible for Meth A tumor eradication induced by zinostatin stimalamer.","8620506",40]
["zinpyr-1","zinpyr-1","C501987","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2006,"16998866","Single and three-color flow cytometry assay for intracellular zinc ion availability in human lymphocytes with Zinpyr-1 and double immunofluorescence: relationship with metallothioneins.","16998866",40]
["zinpyr-1","zinpyr-1","C501987","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2006,"16998866","Single and three-color flow cytometry assay for intracellular zinc ion availability in human lymphocytes with Zinpyr-1 and double immunofluorescence: relationship with metallothioneins.","16998866",40]
["zinquin","zinquin","C084731","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21905645","Reactions of the fluorescent sensor, Zinquin, with the zinc-proteome: adduct formation and ligand substitution.","21905645",40]
["zinterol","zinterol","C002904","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2001,"11325796","Murine ventricular L-type Ca(2+) current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor.","11325796",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C140099,B140099)","v":"ziprasidone"},"ziprasidone","C092292","5_AO",827,5,"skin","sensitisation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J140099,K140099)","v":"Drug Eruptions"},"D003875","Drug Eruptions",0,1,2012,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q140099,Q140099)","v":"22611746"},"Drug rash with eosinophilia and systemic symptoms (DRESS syndrome).","22611746",40]
["ziprasidone","ziprasidone","C092292","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"18032984","Clinical relevance of relative receptor binding affinity: quetiapine and ziprasidone as examples.","18032984",40]
["Ziram","Ziram","D015039","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2000,"10908178","Allergic contact dermatitis to socks presenting as bleached rubber syndrome.","10908178",40]
["Ziram","Ziram","D015039","5_AO",827,5,"skin","sensitisation","Dermatitis, Allergic Contact","D017449","Dermatitis, Allergic Contact",0,2,2003,"12786726","Patch testing with zinc dibenzyldithiocarbamate. A multicentre study of the Information Network of Departments of Dermatology and the German Contact Dermatitis Research Group.","12786726",40]
["Ziram","Ziram","D015039","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,2,1988,"2972524","Contact dermatitis due to Ziram and Maneb.","2972524",40]
["Ziram","Ziram","D015039","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2004,"15526271","Effects of in vitro exposure to low levels of organotin and carbamate pesticides on human natural killer cell cytotoxic function.","15526271",40]
["ziyuglycoside I","ziyuglycoside I","C484848","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2008,"18256460","Anti-wrinkle activity of ziyuglycoside I isolated from a Sanguisorba officinalis root extract and its application as a cosmeceutical ingredient.","18256460",40]
["ZK 118182","ZK 118182","C067426","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11937363","3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents.","11937363",40]
["ZK 156718","ZK 156718","C447607","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"11779200","ZK 156718, a low calcemic, antiproliferative, and prodifferentiating vitamin D analog.","11779200",40]
["ZK 191784","ZK 191784","C470666","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2007,"18161923","Calcitriol analog ZK191784 ameliorates acute and chronic dextran sodium sulfate-induced colitis by modulation of intestinal dendritic cell numbers and phenotype.","18161923",40]
["ZK 191784","ZK 191784","C470666","5_AO",827,5,"skin","sensitisation","Dermatitis, Contact","D003877","Dermatitis, Contact",0,-1,2002,"12485451","A novel immunosuppressive 1alpha,25-dihydroxyvitamin D3 analog with reduced hypercalcemic activity.","12485451",40]
["ZK 191784","ZK 191784","C470666","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2002,"12485451","A novel immunosuppressive 1alpha,25-dihydroxyvitamin D3 analog with reduced hypercalcemic activity.","12485451",40]
["ZK 200775","ZK 200775","C114423","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2000,"10613825","Autoimmune encephalomyelitis ameliorated by AMPA antagonists.","10613825",40]
["ZK 216348","ZK 216348","C481822","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2004,"14694204","Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects.","14694204",40]
["ZK 93426","ZK 93426","C042568","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"8594163","The atom assignment problem in automated de novo drug design. 5. Tests for envelope-directed fragment placement based on molecular similarity.","8594163",40]
["ZK159222","ZK159222","C410228","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2005,"15647825","1,25-Dihydroxyvitamin D3 stimulates cyclic vitamin D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetylation in intact osteoblasts.","15647825",40]
["ZK203278","ZK203278","C544428","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2009,"19239489","Immunomodulation by a novel, dissociated Vitamin D analogue.","19239489",40]
["ZK203278","ZK203278","C544428","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21169995","Control of T cell activation by vitamin D.","21169995",40]
["ZM 241385","ZM 241385","C097270","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2002,"12382078","Localization of adenosine A2A-receptors in rat brain with [3H]ZM-241385.","12382078",40]
["ZM 241385","ZM 241385","C097270","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15013482","Binding of tritiated and radioiodinated ZM241,385 to brain A2A adenosine receptors.","15013482",40]
["ZM 241385","ZM 241385","C097270","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15507221","Characterization of [3H]ZM 241385 binding in wild-type and adenosine A2A receptor knockout mice.","15507221",40]
["ZM 241385","ZM 241385","C097270","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2009,"19461661","Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008.","19461661",40]
["ZM 241385","ZM 241385","C097270","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20147292","Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues.","20147292",40]
["ZM 241385","ZM 241385","C097270","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21885291","Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine.","21885291",40]
["ZM 241385","ZM 241385","C097270","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2017,"28984574","Ligand modulation of sidechain dynamics in a wild-type human GPCR.","28984574",40]
["ZM 253270","ZM 253270","C095798","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7562491","Pharmacological characterization of a new class of nonpeptide neurokinin A antagonists that demonstrate species selectivity.","7562491",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2003,"12859150","Zinc octa-n-alkyl phthalocyanines in photodynamic therapy: photophysical properties, accumulation and apoptosis in cell cultures, studies in erythrocytes and topical application to Balb/c mice skin.","12859150",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2005,"15880654","Loss of E-cadherin mediated cell-cell adhesion as an early trigger of apoptosis induced by photodynamic treatment.","15880654",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2006,"16427302","Zn(II)-phthalocyanines as phototherapeutic agents for cutaneous diseases. Photosensitization of fibroblasts and keratinocytes.","16427302",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"17058928","[Spectroscopic studies on the interactions of a hexadeca-carboxy zinc phthalocyanine and serum albumin and preparation of the bioconjugates].","17058928",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21152655","A set of highly water-soluble tetraethyleneglycol-substituted Zn(II) phthalocyanines: synthesis, photochemical and photophysical properties, interaction with plasma proteins and in vitro phototoxicity.","21152655",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21536490","Photophysical, photochemical and BSA binding/BQ quenching properties of quaternizable coumarin containing water soluble zinc phthalocyanine complexes.","21536490",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"23827257","Rational design of a zinc phthalocyanine binding protein.","23827257",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24341134","Photodynamic therapy of Porphyromonas gingivalis via liposome-encapsulated sensitizers.","24341134",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24451248","Saccharide substituted zinc phthalocyanines: optical properties, interaction with bovine serum albumin and near infrared fluorescence imaging for sentinel lymph nodes.","24451248",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1987,"3559547","Spectroscopic studies on Zn(II)-phthalocyanine in homogeneous and microheterogeneous systems.","3559547",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"8581821","The effect of different liposomal formulations on the interaction of Zn(II)-phthalocyanine with isolated low and high density lipoproteins.","8581821",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2003,"12859150","Zinc octa-n-alkyl phthalocyanines in photodynamic therapy: photophysical properties, accumulation and apoptosis in cell cultures, studies in erythrocytes and topical application to Balb/c mice skin.","12859150",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1992,"1403374","Dark induction of haem oxygenase messenger RNA by haematoporphyrin derivative and zinc phthalocyanine; agents for photodynamic therapy.","1403374",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2011,"21128702","Improving the topical delivery of zinc phthalocyanine using oleic acid as a penetration enhancer: in vitro permeation and retention.","21128702",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2016,"27064601","Delivery of a hydrophobic phthalocyanine photosensitizer using PEGylated gold nanoparticle conjugates for the in vivo photodynamic therapy of amelanotic melanoma.","27064601",40]
["Zn(II)-phthalocyanine","Zn(II)-phthalocyanine","C052159","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1996,"8725049","Light scattering of human skin: a comparison between zinc (II)-phthalocyanine and photofrin II.","8725049",40]
["ZnPc(COOH)16","ZnPc(COOH)16","C549929","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"17058928","[Spectroscopic studies on the interactions of a hexadeca-carboxy zinc phthalocyanine and serum albumin and preparation of the bioconjugates].","17058928",40]
["Zolazepam","Zolazepam","D015041","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1992,"1483902","Effect of tiletamine/zolazepam sedation on intradermal allergy testing in atopic dogs.","1483902",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,3,2011,"21673342","DC-like cell-dependent activation of human natural killer cells by the bisphosphonate zoledronic acid is regulated by γδ T lymphocytes.","21673342",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2011,"21903898","Zoledronate activates NK cells.","21903898",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2007,"17118497","Enhancement of BCG-induced Th1 immune response through Vgamma9Vdelta2 T cell activation with non-peptidic drugs.","17118497",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2009,"19555208","Zoledronic acid, an aminobisphosphonate, modulates differentiation and maturation of human dendritic cells.","19555208",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2008,"18156189","Copulsing tumor antigen-pulsed dendritic cells with zoledronate efficiently enhance the expansion of tumor antigen-specific CD8+ T cells via Vgamma9gammadelta T cell activation.","18156189",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2011,"21753152","Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells.","21753152",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,3,2013,"23593363","Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells.","23593363",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","CD8-Positive T-Lymphocytes","D018414","CD8-Positive T-Lymphocytes",1,1,2016,"26828454","Zoledronic acid induces dose-dependent increase of antigen-specific CD8 T-cell responses in combination with peptide/poly-IC vaccine.","26828454",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2006,"16956814","The effect of zoledronic acid on the function and differentiation of myeloid cells.","16956814",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2007,"17118497","Enhancement of BCG-induced Th1 immune response through Vgamma9Vdelta2 T cell activation with non-peptidic drugs.","17118497",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2007,"17301819","Zoledronic acid inhibits the function of Toll-like receptor 4 ligand activated monocyte-derived dendritic cells.","17301819",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2007,"17403919","Enhanced ability of dendritic cells to stimulate innate and adaptive immunity on short-term incubation with zoledronic acid.","17403919",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2008,"18156189","Copulsing tumor antigen-pulsed dendritic cells with zoledronate efficiently enhance the expansion of tumor antigen-specific CD8+ T cells via Vgamma9gammadelta T cell activation.","18156189",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2009,"19238075","Zoledronic acid and interleukin-2 treatment improves immunocompetence in HIV-infected persons by activating Vgamma9Vdelta2 T cells.","19238075",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2009,"19555208","Zoledronic acid, an aminobisphosphonate, modulates differentiation and maturation of human dendritic cells.","19555208",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"20549316","Coculturing dendritic cells with zoledronate acid efficiently enhance the anti-tumor effects of cytokine-induced killer cells.","20549316",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2010,"20582413","Aminobisphosphonate-pretreated dendritic cells trigger successful Vgamma9Vdelta2 T cell amplification for immunotherapy in advanced cancer patients.","20582413",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2011,"21477159","A phase I/IIa clinical trial of immunotherapy for elderly patients with acute myeloid leukaemia using dendritic cells co-pulsed with WT1 peptide and zoledronate.","21477159",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"21673342","DC-like cell-dependent activation of human natural killer cells by the bisphosphonate zoledronic acid is regulated by γδ T lymphocytes.","21673342",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2011,"21753152","Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells.","21753152",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C140163,B140163)","v":"zoledronic acid"},"zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J140163,K140163)","v":"Dendritic Cells"},"D003713","Dendritic Cells",1,1,2011,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q140163,Q140163)","v":"21903898"},"Zoledronate activates NK cells.","21903898",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"22075551","Zoledronic acid modulates maturation of human monocyte-derived dendritic cells.","22075551",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2013,"23593363","Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells.","23593363",40]
["zoledronic acid","zoledronic acid","C088658","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2014,"25483657","The effects of zoledronate on monocyte-derived dendritic cells from melanoma patients differ depending on the clinical stage of the disease.","25483657",40]
["zoledronic acid","zoledronic acid","C088658","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2012,"23157790","Drug-induced dermatomyositis after zoledronic acid.","23157790",40]
["zoledronic acid","zoledronic acid","C088658","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2015,"26437156","Zoledronic acid-associated symmetrical drug-related intertriginous and flexural exanthema (SDRIFE): report of baboon syndrome in a woman with recurrent metastatic breast cancer after receiving zoledronic acid.","26437156",40]
["zoledronic acid","zoledronic acid","C088658","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2015,"26588338","Zoledronic Acid-Induced Interface Dermatitis.","26588338",40]
["zoledronic acid","zoledronic acid","C088658","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2012,"21225298","The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes--in vitro study.","21225298",40]
["zoledronic acid","zoledronic acid","C088658","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2011,"21551338","Bisphosphonates inhibit expression of p63 by oral keratinocytes.","21551338",40]
["zoledronic acid","zoledronic acid","C088658","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2012,"22172403","Zoledronic acid induces S-phase arrest via a DNA damage response in normal human oral keratinocytes.","22172403",40]
["zoledronic acid","zoledronic acid","C088658","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2012,"22182245","Low concentration amino-bisphosphonates stimulate human keratinocyte proliferation and in vitro wound healing.","22182245",40]
["zoledronic acid","zoledronic acid","C088658","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2012,"22650360","Exposing human epithelial cells to zoledronic acid can mediate osteonecrosis of jaw: an in vitro model.","22650360",40]
["zoledronic acid","zoledronic acid","C088658","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23428615","Low zoledronate concentrations stimulate human keratinocyte proliferation.","23428615",40]
["zoledronic acid","zoledronic acid","C088658","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2013,"23773293","Zoledronic acid decreases gene expression of vascular endothelial growth factor and basic fibroblast growth factor by human epithelial cells.","23773293",40]
["zoledronic acid","zoledronic acid","C088658","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,1,2014,"24021731","Zoledronic acid impairs re-epithelialization through down-regulation of integrin αvβ6 and transforming growth factor beta signalling in a three-dimensional in vitro wound healing model.","24021731",40]
["zoledronic acid","zoledronic acid","C088658","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2014,"24342576","In vitro effect of bisphosphonates on oral keratinocytes and fibroblasts.","24342576",40]
["zoledronic acid","zoledronic acid","C088658","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2015,"25913629","The influence of geranylgeraniol on human oral keratinocytes after bisphosphonate treatment: An in vitro study.","25913629",40]
["zoledronic acid","zoledronic acid","C088658","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16684881","The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.","16684881",40]
["zoledronic acid","zoledronic acid","C088658","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"18625688","Biodistribution and plasma protein binding of zoledronic acid.","18625688",40]
["zoledronic acid","zoledronic acid","C088658","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20462513","Delivery of zoledronic acid encapsulated in folate-targeted liposome results in potent in vitro cytotoxic activity on tumor cells.","20462513",40]
["zoledronic acid","zoledronic acid","C088658","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2012,"22392982","Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity.","22392982",40]
["zoledronic acid","zoledronic acid","C088658","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2014,"24968029","Macrophage depletion by free bisphosphonates and zoledronate-loaded red blood cells.","24968029",40]
["zoledronic acid","zoledronic acid","C088658","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26318908","The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.","26318908",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21496396","Zoledronic acid enhances Vδ2 T-lymphocyte antitumor response to human glioma cell lines.","21496396",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2003,"12959943","Induction of gammadelta T-lymphocyte effector functions by bisphosphonate zoledronic acid in cancer patients in vivo.","12959943",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2005,"15756684","Cytotoxic effects of gammadelta T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy.","15756684",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2006,"16698685","Type I IFN-mediated enhancement of anti-leukemic cytotoxicity of gammadelta T cells expanded from peripheral blood cells by stimulation with zoledronate.","16698685",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2007,"17403919","Enhanced ability of dendritic cells to stimulate innate and adaptive immunity on short-term incubation with zoledronic acid.","17403919",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2007,"17457212","Zoledronic acid has direct antiproliferative and antimetastatic effect on pancreatic carcinoma cells and acts as an antigen for delta2 gamma/delta T cells.","17457212",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17671215","Targeting human {gamma}delta} T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer.","17671215",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2008,"18297280","Zoledronic acid modulates antitumoral responses of prostate cancer-tumor associated macrophages.","18297280",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2009,"18458903","In vivo effects of zoledronic acid on peripheral gammadelta T lymphocytes in early breast cancer patients.","18458903",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2008,"19016372","Zoledronate facilitates large-scale ex vivo expansion of functional gammadelta T cells from cancer patients for use in adoptive immunotherapy.","19016372",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2009,"19016713","Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.","19016713",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2009,"19250873","Regression of melanoma metastases following treatment with the n-bisphosphonate zoledronate and localised radiotherapy.","19250873",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2009,"19400555","Induction of gamma delta T cells using zoledronate plus interleukin-2 in patients with metastatic cancer.","19400555",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2010,"20445349","Effect of IL-18 on expansion of gammadelta T cells stimulated by zoledronate and IL-2.","20445349",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2010,"20681408","Zoledronate stimulates gamma delta T cells in prostate cancer patients.","20681408",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"20831354","Zoledronate-activated Vγ9γδ T cell-based immunotherapy is feasible and restores the impairment of γδ T cells in patients with solid tumors.","20831354",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21034859","Multicompartment vectors as novel drug delivery systems: selective activation of Tγδ lymphocytes after zoledronic acid delivery.","21034859",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21047568","Fluvastatin does not prevent the acute-phase response to intravenous zoledronic acid in post-menopausal women.","21047568",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2010,"21069948","Lysis of aminobisphosphonate-sensitized MCF-7 breast tumor cells by Vγ9Vδ2 T cells.","21069948",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2010,"21138682","[gammadelta T cells stimulated by zoledronate kill osteosarcoma cells].","21138682",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21304399","Adoptive immunotherapy for advanced non-small cell lung cancer using zoledronate-expanded γδTcells: a phase I clinical study.","21304399",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21646473","High phosphoantigen levels in bisphosphonate-treated human breast tumors promote Vgamma9Vdelta2 T-cell chemotaxis and cytotoxicity in vivo.","21646473",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21647691","Pilot trial of interleukin-2 and zoledronic acid to augment γδ T cells as treatment for patients with refractory renal cell carcinoma.","21647691",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21673342","DC-like cell-dependent activation of human natural killer cells by the bisphosphonate zoledronic acid is regulated by γδ T lymphocytes.","21673342",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21843051","New perspectives on zoledronic acid in breast cancer: potential augmentation of anticancer immune response.","21843051",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21847128","Clinical evaluation of autologous gamma delta T cell-based immunotherapy for metastatic solid tumours.","21847128",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2011,"21903898","Zoledronate activates NK cells.","21903898",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"21931292","Expansion of human peripheral blood γδ T cells using zoledronate.","21931292",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2012,"22025284","Sensitization of human osteosarcoma cells to Vγ9Vδ2 T-cell-mediated cytotoxicity by zoledronate.","22025284",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2012,"22029653","Gamma delta T cells from HIV+ donors can be expanded in vitro by zoledronate/interleukin-2 to become cytotoxic effectors for antibody-dependent cellular cytotoxicity.","22029653",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2011,"22075551","Zoledronic acid modulates maturation of human monocyte-derived dendritic cells.","22075551",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22863589","[Amplification of  γδ T cells in PBMCs of healthy donors and osteosarcoma patients stimulated by zoledronate].","22863589",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"22996365","Zoledronate sensitizes neuroblastoma-derived tumor-initiating cells to cytolysis mediated by human γδ T cells.","22996365",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"23052225","Long-term effects of amino-bisphosphonates on circulating γδ T cells.","23052225",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2013,"23074158","Monocytes and γδ T cells control the acute-phase response to intravenous zoledronate: insights from a phase IV safety trial.","23074158",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2012,"23187773","Updates in the treatment of multiple myeloma.","23187773",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23294710","[Effect of zoledronate on the cytotoxicity of γδ T cells from PBMCs of osteosarcoma patients against osteosarcoma].","23294710",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23321500","Potent antitumor activity of zoledronic acid-induced Vγ9Vδ2 T cells against primary effusion lymphoma.","23321500",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23387443","Comparison of γδ T cell responses and farnesyl diphosphate synthase inhibition in tumor cells pretreated with zoledronic acid.","23387443",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23794630","Essential requirements of zoledronate-induced cytokine and γδ T cell proliferative responses.","23794630",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2013,"23835291","A randomized phase II trial evaluating different schedules of zoledronic acid on bone mineral density in patients with prostate cancer beginning androgen deprivation therapy.","23835291",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C140227,B140227)","v":"zoledronic acid"},"zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J140227,K140227)","v":"T-Lymphocytes"},"D013601","T-Lymphocytes",1,3,2014,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q140227,Q140227)","v":"24162933"},"Neutrophil uptake of nitrogen-bisphosphonates leads to the suppression of human peripheral blood γδ T cells.","24162933",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2014,"24515916","Intraperitoneal injection of in vitro expanded Vγ9Vδ2 T cells together with zoledronate for the treatment of malignant ascites due to gastric cancer.","24515916",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2014,"25421542","Effects of zoledronic acid and the association between its efficacy and γδT cells in postmenopausal women with breast cancer treated with preoperative hormonal therapy: a study protocol.","25421542",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"25444923","Upregulation of the mevalonate pathway by cholesterol depletion abolishes tolerance to N-bisphosphonate induced Vγ9Vδ2 T cell cytotoxicity in PC-3 prostate cancer cells.","25444923",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"25544757","Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma.","25544757",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2015,"26047704","Isopentenyl pyrophosphate secreted from Zoledronate-stimulated myeloma cells, activates the chemotaxis of γδT cells.","26047704",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2016,"26811335","Analysis of Immune Cells from Human Mammary Ductal Epithelial Organoids Reveals Vδ2+ T Cells That Efficiently Target Breast Carcinoma Cells in the Presence of Bisphosphonate.","26811335",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2016,"26999703","Zoledronic acid increases the circulating soluble RANKL level in mice, with a further increase in lymphocyte-derived soluble RANKL in zoledronic acid- and glucocorticoid-treated mice stimulated with bacterial lipopolysaccharide.","26999703",40]
["zoledronic acid","zoledronic acid","C088658","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2016,"27763869","Therapeutic Potential of Zoledronate-Activated Autologous γδT Cells in Atopic Dermatitis.","27763869",40]
["zolmitriptan","zolmitriptan","C089750","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2004,"15118377","Fixed drug eruption of the penis due to zolmitriptan.","15118377",40]
["zolpidem","zolpidem","C049109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2002,"12449497","Mechanism-based pharmacodynamic modeling of the interaction of midazolam, bretazenil, and zolpidem with ethanol.","12449497",40]
["zolpidem","zolpidem","C049109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2007,"17360122","Status epilepticus alters zolpidem sensitivity of [3H]flunitrazepam binding in the developing rat brain.","17360122",40]
["zolpidem","zolpidem","C049109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17451983","Modeling of alphak/gamma2 (k=1, 2, 3 and 5) interface of GABA A receptor and docking studies with zolpidem: implications for selectivity.","17451983",40]
["zolpidem","zolpidem","C049109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2010,"20652804","The effects of zolpidem treatment and withdrawal on the in vitro expression of recombinant alpha1beta2gamma2s GABA(A) receptors expressed in HEK 293 cells.","20652804",40]
["zolpidem","zolpidem","C049109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21103864","Emergence of anti-conflict effects of zolpidem in rhesus monkeys following extended post-injection intervals.","21103864",40]
["zolpidem","zolpidem","C049109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2011,"21616065","Actions of two GABAA receptor benzodiazepine-site ligands that are mediated via non-γ2-dependent modulation.","21616065",40]
["zolpidem","zolpidem","C049109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22922343","Differential effects of short- and long-term zolpidem treatment on recombinant α1β2γ2s subtype of GABA(A) receptors in vitro.","22922343",40]
["zolpidem","zolpidem","C049109","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3198298","Plasma protein binding of zolpidem in liver and renal insufficiency.","3198298",40]
["zomepirac","zomepirac","C020549","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,3,1982,"7081784","Anaphylactic reaction to zomepirac.","7081784",40]
["zomepirac","zomepirac","C020549","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10507755","Limitations of hepatocytes and liver homogenates in modelling in vivo formation of acyl glucuronide-derived drug-protein adducts.","10507755",40]
["zomepirac","zomepirac","C020549","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"11197750","Bile duct ligation promotes covalent drug-protein adduct formation in plasma but not in liver of rats given zomepirac.","11197750",40]
["zomepirac","zomepirac","C020549","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2299592","Effect of esterase inhibition on the disposition of zomepirac glucuronide and its covalent binding to plasma proteins in the guinea pig.","2299592",40]
["zomepirac","zomepirac","C020549","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"3949982","Irreversible binding of zomepirac to plasma protein in vitro and in vivo.","3949982",40]
["zomepirac","zomepirac","C020549","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6480878","Zomepirac--aspirin interactions in man.","6480878",40]
["zomepirac","zomepirac","C020549","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6627828","Influence of uremia, hemodialysis, and nonesterified fatty acids on zomepirac plasma protein binding.","6627828",40]
["zomepirac","zomepirac","C020549","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1980,"6769977","Review of the pharmacokinetics and metabolism of zomepirac in man and animals.","6769977",40]
["zomepirac","zomepirac","C020549","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1981,"7264940","Plasma protein binding of zomepirac sodium.","7264940",40]
["zomepirac","zomepirac","C020549","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1995,"7487878","Synthesis and mass-spectrometric characterization of human serum albumins modified by covalent binding of two non-steroidal anti-inflammatory drugs: tolmetin and zomepirac.","7487878",40]
["zomepirac glucuronide","zomepirac glucuronide","C027368","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"10507755","Limitations of hepatocytes and liver homogenates in modelling in vivo formation of acyl glucuronide-derived drug-protein adducts.","10507755",40]
["zomepirac glucuronide","zomepirac glucuronide","C027368","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"1981713","Covalent binding of zomepirac glucuronide to proteins: evidence for a Schiff base mechanism.","1981713",40]
["zomepirac glucuronide","zomepirac glucuronide","C027368","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1990,"2299592","Effect of esterase inhibition on the disposition of zomepirac glucuronide and its covalent binding to plasma proteins in the guinea pig.","2299592",40]
["zonisamide","zonisamide","C022189","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2008,"18637135","Predicting possible zonisamide hypersensitivity syndrome.","18637135",40]
["zonisamide","zonisamide","C022189","5_AO",827,5,"skin","sensitisation","Drug Eruptions","D003875","Drug Eruptions",0,2,2011,"21998830","Case of drug rash with eosinophilia and systemic symptoms induced by zonisamide and reactivation of human herpes virus 7.","21998830",40]
["zonisamide","zonisamide","C022189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2004,"15270757","Dialyzability of the antiepileptic drug zonisamide in patients undergoing hemodialysis.","15270757",40]
["zonisamide","zonisamide","C022189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2008,"19000278","Disposition and safety of zonisamide after intravenous and oral single dose and oral multiple dosing in normal hound dogs.","19000278",40]
["zonisamide","zonisamide","C022189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21175212","Interactions of monoamine oxidases with the antiepileptic drug zonisamide: specificity of inhibition and structure of the human monoamine oxidase B complex.","21175212",40]
["zonisamide","zonisamide","C022189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23811149","Study on the interaction of the epilepsy drug, zonisamide with human serum albumin (HSA) by spectroscopic and molecular docking techniques.","23811149",40]
["zonisamide","zonisamide","C022189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"4049458","Blood-brain barrier transport of CI-912: single-passage equilibration of erythrocyte-borne drug.","4049458",40]
["zonisamide","zonisamide","C022189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1983,"6138046","Absorption, distribution and excretion of 3-(sulfamoyl[14C]methyl)-1,2-benziosoxazole (AD-810) in Rats, Dogs and Monkeys and of AD-810 in Men.","6138046",40]
["zonisamide","zonisamide","C022189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1995,"7573757","Drug interactions of zonisamide with phenytoin and sodium valproate: serum concentrations and protein binding.","7573757",40]
["zonisamide","zonisamide","C022189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1994,"7925145","Influence of additional therapy with zonisamide (Excegran) on protein binding and metabolism of carbamazepine.","7925145",40]
["zonisamide","zonisamide","C022189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1993,"8271568","Concentrations of zonisamide in serum, free fraction, mixed saliva and cerebrospinal fluid in epileptic children treated with monotherapy.","8271568",40]
["zonisamide","zonisamide","C022189","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1993,"8401412","Pharmacokinetic interaction of zonisamide in rats. Effect of zonisamide on other antiepileptics.","8401412",40]
["zopiclone","zopiclone","C515050","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21481885","On the zopiclone enantioselective binding to human albumin and plasma proteins. An electrokinetic chromatography approach.","21481885",40]
["zopiclone","zopiclone","C515050","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1999,"9951403","Stereoselective binding of zopiclone to human plasma proteins.","9951403",40]
["zopolrestat","zopolrestat","C067172","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1991,"1808615","Pharmacokinetics of zopolrestat, a carboxylic acid aldose reductase inhibitor, in normal and diabetic rats.","1808615",40]
["zopolrestat","zopolrestat","C067172","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"23857942","Zopolrestat as a human glyoxalase I inhibitor and its structural basis.","23857942",40]
["zopolrestat","zopolrestat","C067172","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8780524","Kinetic and spectroscopic evidence for active site inhibition of human aldose reductase.","8780524",40]
["zosteric acid","zosteric acid","C503399","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26132116","Unravelling the Structural and Molecular Basis Responsible for the Anti-Biofilm Activity of Zosteric Acid.","26132116",40]
["zosterin","zosterin","C070927","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2001,"11697245","[Comparative immunologic activity of marine bioglycans].","11697245",40]
["zosuquidar trihydrochloride","zosuquidar trihydrochloride","C095179","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2006,"16434546","Dependence of nelfinavir brain uptake on dose and tissue concentrations of the selective P-glycoprotein inhibitor zosuquidar in rats.","16434546",40]
["zosuquidar trihydrochloride","zosuquidar trihydrochloride","C095179","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1996,"8797588","Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979.","8797588",40]
["zotarolimus","zotarolimus","C489443","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Delayed","D006968","Hypersensitivity, Delayed",0,2,2007,"17438408","Zotarolimus, a novel sirolimus analogue with potent anti-proliferative activity on coronary smooth muscle cells and reduced potential for systemic immunosuppression.","17438408",40]
["zotarolimus","zotarolimus","C489443","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2007,"17438408","Zotarolimus, a novel sirolimus analogue with potent anti-proliferative activity on coronary smooth muscle cells and reduced potential for systemic immunosuppression.","17438408",40]
["zoxamide","zoxamide","C451427","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2015,"26596626","M233I Mutation in the β-Tubulin of Botrytis cinerea Confers Resistance to Zoxamide.","26596626",40]
["Zoxazolamine","Zoxazolamine","D015049","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1989,"2585278","Kinetics of drug action in disease states. XXXV: Effect of hypovolemia on the pharmacodynamics of zoxazolamine in rats.","2585278",40]
["Zoxazolamine","Zoxazolamine","D015049","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1986,"2872034","Dose-dependent pharmacokinetics of zoxazolamine in the rat.","2872034",40]
["Zoxazolamine","Zoxazolamine","D015049","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1988,"3247308","Pharmacodynamics of zoxazolamine and chlorzoxazone in rats.","3247308",40]
["Zoxazolamine","Zoxazolamine","D015049","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1984,"6149908","Effects of model traumatic injury on hepatic drug metabolism in the rat. II. In vivo metabolism of hexobarbital and zoxazolamine.","6149908",40]
["ZSTK474","ZSTK474","C510150","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2014,"24844601","ZSTK474, a novel PI3K inhibitor, modulates human CD14+ monocyte-derived dendritic cell functions and suppresses experimental autoimmune encephalomyelitis.","24844601",40]
["ZSTK474","ZSTK474","C510150","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,2014,"24844601","ZSTK474, a novel PI3K inhibitor, modulates human CD14+ monocyte-derived dendritic cell functions and suppresses experimental autoimmune encephalomyelitis.","24844601",40]
["zuonin A","zuonin A","C579789","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2013,"24001752","Elucidating binding modes of zuonin A enantiomers to JNK1 via in silico methods.","24001752",40]
["zwittergent 3-12","zwittergent 3-12","C034730","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,2,1992,"1524210","Use of a zwitterionic detergent for the restoration of the antibody binding capacity of immunoblotted Francisella tularensis lipopolysaccharide.","1524210",40]
["zwittergent 3-12","zwittergent 3-12","C034730","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2000,"10870829","Quantitative determination of zwitterionic detergents using salt-induced phase separation of Triton X-100.","10870829",40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C140291,B140291)","v":"Zymosan"},"Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J140291,K140291)","v":"Antigen-Antibody Reactions"},"D000937","Antigen-Antibody Reactions",1,1,1975,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q140291,Q140291)","v":"1170051"},"Participation of an early component of complement and Hageman factor in C3 destruction by zymosan.","1170051",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1958,"13628858","[The influence of zymosan on antibody behavior].","13628858",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1962,"14016298","[Action of zymosan on the production of agglutinins by Salmonella typhosa O and H agglutinogens].","14016298",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1963,"14074392","MOTION PICTURE STUDIES ON DEGRANULATION OF HORSE EOSINOPHILS DURING PHAGOCYTOSIS.","14074392",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1965,"14316948","THE ROLE OF SERUM COMPLEMENT IN CHEMOTAXIS OF LEUKOCYTES IN VITRO.","14316948",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1965,"14321431","MOUSE BETA-1C-GLOBULIN: PRODUCTION OF ANTISERUM AND CHARACTERIZATION IN THE COMPLEMENT REACTION.","14321431",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1989,"2705780","Possible involvement of a 95-kDa protein phosphorylation in phorbol 12-myristate 13-acetate-induced suppression of zymosan phagocytosis in guinea pig macrophages.","2705780",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1988,"3351307","Monoclonal antibodies against the major zymosan-induced chemotactic factor in rabbit serum.","3351307",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1967,"4164055","Role of the thymus in tolerance. V. Suppressive effect of treatment with nonaggregated and aggregated bovine gamma-globulin on specific immune responses in normal adult rats.","4164055",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1974,"4607759","Induction of host resistance in different mouse strains.","4607759",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Antibody Reactions","D000937","Antigen-Antibody Reactions",1,1,1973,"4707840","The influence of stimulation with Zymosan on the total complement level in lung cancer and tuberculosis.","4707840",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Antigen-Presenting Cells","D000938","Antigen-Presenting Cells",1,1,2006,"16543948","Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance.","16543948",40]
["Zymosan","Zymosan","D015054","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,3,2013,"23010280","Low dose zymosan ameliorates both chronic and relapsing experimental autoimmune encephalomyelitis.","23010280",40]
["Zymosan","Zymosan","D015054","4_KE",272,4,"T-cells","Activation/Proliferation","CD4-Positive T-Lymphocytes","D015496","CD4-Positive T-Lymphocytes",1,1,2014,"24993442","Epicutaneous immunization with TNP-Ig and Zymosan induces TCRαβ+ CD4+ contrasuppressor cells that reverse skin-induced suppression via IL-17A.","24993442",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2003,"12761116","Differential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles.","12761116",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2005,"15728245","Regulated recruitment of DC-SIGN to cell-cell contact regions during zymosan-induced human dendritic cell aggregation.","15728245",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2006,"16543948","Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance.","16543948",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2006,"16730865","Female genital tract immunization: evaluation of candidate immunoadjuvants on epithelial cell secretion of CCL20 and dendritic/Langerhans cell maturation.","16730865",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2007,"17312158","Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells.","17312158",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2007,"17458858","Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan.","17458858",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2007,"17568998","Nonspecific immunotherapy with intratumoral lipopolysaccharide and zymosan A but not GM-CSF leads to an effective anti-tumor response in subcutaneous RG-2 gliomas.","17568998",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2009,"19318593","Cyclooxygenase-2 induced by zymosan in human monocyte-derived dendritic cells shows high stability, and its expression is enhanced by atorvastatin.","19318593",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2009,"19509280","Fungal zymosan and mannan activate the cryopyrin inflammasome.","19509280",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2009,"19564345","The induction of IL-10 by zymosan in dendritic cells depends on CREB activation by the coactivators CREB-binding protein and TORC2 and autocrine PGE2.","19564345",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2010,"20087927","Zymosan enhances the mucosal adjuvant activity of poly(I:C) in a nasal influenza vaccine.","20087927",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"21345313","Modulation of TNFSF expression in lymphoid tissue inducer cells by dendritic cells activated with Toll-like receptor ligands.","21345313",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2011,"21486701","GM-CSF plays a key role in zymosan-stimulated human dendritic cells for activation of Th1 and Th17 cells.","21486701",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,1,2015,"25957979","Zymosan Induces Immune Responses Comparable with Those of Adults in Monocytes, Dendritic Cells, and Monocyte-Derived Dendritic Cells from Cord Blood.","25957979",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2015,"26183538","Zymosan and PMA activate the immune responses of Mutz3-derived dendritic cells synergistically.","26183538",40]
["Zymosan","Zymosan","D015054","3_KE",398,3,"Dendritic Cells","Activation","Dendritic Cells","D003713","Dendritic Cells",1,3,2016,"26673542","Pharmacological inhibition of eicosanoids and platelet-activating factor signaling impairs zymosan-induced release of IL-23 by dendritic cells.","26673542",40]
["Zymosan","Zymosan","D015054","5_AO",827,5,"skin","sensitisation","Dermatitis, Atopic","D003876","Dermatitis, Atopic",1,1,1994,"8155999","Eosinophil chemiluminescence response to cytokines and opsonized zymosans in atopic dermatitis.","8155999",40]
["Zymosan","Zymosan","D015054","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1991,"2001066","Effects of zymosan-activated human granulocytes on isolated human airways.","2001066",40]
["Zymosan","Zymosan","D015054","5_AO",827,5,"skin","sensitisation","Hypersensitivity, Immediate","D006969","Hypersensitivity, Immediate",1,1,1995,"8750311","Leukotriene B4 and C4 generation by human leukocytes after ex vivo stimulation with Ca-ionophore and opsonized zymosan in children with atopic asthma.","8750311",40]
["Zymosan","Zymosan","D015054","2_KE",826,2,"Keratinocytes","Activation","Keratinocytes","D015603","Keratinocytes",1,3,2016,"26767426","MALT1 Protease Activity Controls the Expression of Inflammatory Genes in Keratinocytes upon Zymosan Stimulation.","26767426",40]
["Zymosan","Zymosan","D015054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,2001,"11454666","Modulation of haem oxygenase-1 expression by nitric oxide and leukotrienes in zymosan-activated macrophages.","11454666",40]
["Zymosan","Zymosan","D015054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2003,"12817025","Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation and TNF-alpha secretion are down-regulated by lung collectin surfactant protein A.","12817025",40]
["Zymosan","Zymosan","D015054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2007,"17675523","Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly.","17675523",40]
["Zymosan","Zymosan","D015054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2011,"21402701","Notch- and transducin-like enhancer of split (TLE)-dependent histone deacetylation explain interleukin 12 (IL-12) p70 inhibition by zymosan.","21402701",40]
["Zymosan","Zymosan","D015054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,2012,"22851705","The role of properdin in zymosan- and Escherichia coli-induced complement activation.","22851705",40]
["Zymosan","Zymosan","D015054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1977,"268620","Interaction between the third complement protein and cell surface macromolecules.","268620",40]
["Zymosan","Zymosan","D015054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1985,"2981649","Stimulus-dependent inhibition of superoxide generation by prostaglandins.","2981649",40]
["Zymosan","Zymosan","D015054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,1,1985,"4044589","Effect of divalent metal ions and pH upon the binding reactivity of human serum amyloid P component, a C-reactive protein homologue, for zymosan. Preferential reactivity in the presence of copper and acidic pH.","4044589",40]
["Zymosan","Zymosan","D015054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1981,"6462133","The binding of human complement proteins C5, factor B, beta 1H and properdin to complement fragment C3b on zymosan.","6462133",40]
["Zymosan","Zymosan","D015054","1_MIE",396,1,"Protein","Covalent Binding","Protein Binding","D011485","Protein Binding",1,2,1995,"7897229","Zymosan-triggered association of tyrosine phosphoproteins and lyn kinase with cytoskeleton in human monocytes.","7897229",40]
["Zymosan","Zymosan","D015054","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,2013,"23788175","Collagen hydrolysate inhibits zymosan-induced inflammation.","23788175",40]
["Zymosan","Zymosan","D015054","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1978,"702362","Characterization of a histamine-independent vascular permeability-increasing factor generated on exposure of rabbit plasma to zymosan [proceedings].","702362",40]
["Zymosan","Zymosan","D015054","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1997,"9200477","Effect of the inducible nitric oxide synthase inhibitors aminoguanidine and L-N6-(1-iminoethyl)lysine on zymosan-induced plasma extravasation in rat skin.","9200477",40]
["Zymosan","Zymosan","D015054","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2003,"12761116","Differential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles.","12761116",40]
["Zymosan","Zymosan","D015054","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2006,"16977380","Cytokine production profile of splenocytes derived from zymosan A-treated SKG mice developing arthritis.","16977380",40]
["Zymosan","Zymosan","D015054","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1992,"1740643","Characterization of immunosuppressive functions of murine peritoneal macrophages induced with various agents.","1740643",40]
["Zymosan","Zymosan","D015054","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2008,"19005921","Single pre-exposure to a high dose of zymosan enhances lung defense mechanisms and accelerates the pulmonary clearance of a bacterial pathogen in rats.","19005921",40]
["Zymosan","Zymosan","D015054","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,3,1990,"2356533","[Correction of immunologic reactivity in elderly patients with diffuse toxic goiter].","2356533",40]
["Zymosan","Zymosan","D015054","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,2013,"23574321","T cell activation status determines the cytokine pattern induced by zymosan and bacterial DNA both in thymocytes and splenocytes.","23574321",40]
["Zymosan","Zymosan","D015054","4_KE",272,4,"T-cells","Activation/Proliferation","T-Lymphocytes","D013601","T-Lymphocytes",1,1,1974,"4546446","Combined detection of human T and B lymphocytes by rosette formation with sheep erythrocytes and zymosan-C3 complexes.","4546446",40]
["zymosterol","zymosterol","C015582","5_AO",827,5,"skin","sensitisation","Skin","D012867","Skin",0,1,1990,"2205410","Effect of chemical carcinogens on cholesterol biosynthetic pathways in the skin of mice.","2205410",40]