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["Overview - AOP ",null,null,{"$f":"(HYPERLINK(\"https://aopwiki.org/aops/42\",\"aop 42\"))","v":"aop 42"}]
["TPO Inhibition and Altered Neurodevelopment"]
["MeSH Chemical Name (hyperlinked) ","ChemName","chemuid","1_MIE","2_KE","3_KE","5_KE","8_AO"]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4,B4)","v":"Propylthiouracil"},"Propylthiouracil","D011441",899,1171,692,39,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5,B5)","v":"Amiodarone"},"Amiodarone","D000638",627,288,379,33,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C6,B6)","v":"Thiouracil"},"Thiouracil","D013889",536,192,264,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7,B7)","v":"Methimazole"},"Methimazole","D008713",478,1349,468,21,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8,B8)","v":"Potassium Iodide"},"Potassium Iodide","D011193",330,85,165,2,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C9,B9)","v":"Methylthiouracil"},"Methylthiouracil","D008779",305,118,138,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C10,B10)","v":"Thiourea"},"Thiourea","D013890",282,69,90,90,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C11,B11)","v":"Glucose"},"Glucose","D005947",258,128,265,3491,144]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C12,B12)","v":"Cholesterol"},"Cholesterol","D002784",244,170,564,1463,81]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C13,B13)","v":"Hydrogen Peroxide"},"Hydrogen Peroxide","D006861",219,61,18,694,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C14,B14)","v":"Serotonin"},"Serotonin","D012701",212,42,154,7158,223]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C15,B15)","v":"Epinephrine"},"Epinephrine","D004837",198,89,363,161,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C16,B16)","v":"Norepinephrine"},"Norepinephrine","D009638",194,87,287,3248,33]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C17,B17)","v":"Ethanol"},"Ethanol","D000431",159,63,147,4518,479]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C18,B18)","v":"Dexamethasone"},"Dexamethasone","D003907",158,57,230,2148,62]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C19,B19)","v":"perchlorate"},"perchlorate","C494474",156,48,51,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C20,B20)","v":"Propranolol"},"Propranolol","D011433",144,112,280,143,41]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C21,B21)","v":"Vitamin A"},"Vitamin A","D014801",138,49,152,214,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C22,B22)","v":"Sodium Pertechnetate Tc 99m"},"Sodium Pertechnetate Tc 99m","D013670",134,24,30,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C23,B23)","v":"Sodium Chloride, Dietary"},"Sodium Chloride, Dietary","D017673",118,51,46,71,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C24,B24)","v":"Radioactive Fallout"},"Radioactive Fallout","D011847",114,6,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C25,B25)","v":"sodium perchlorate"},"sodium perchlorate","C031068",108,27,30,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C26,B26)","v":"Tetradecanoylphorbol Acetate"},"Tetradecanoylphorbol Acetate","D013755",108,16,12,757,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C27,B27)","v":"Ascorbic Acid"},"Ascorbic Acid","D001205",102,40,116,412,29]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C28,B28)","v":"Povidone-Iodine"},"Povidone-Iodine","D011206",101,18,77,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C29,B29)","v":"Sodium Iodide"},"Sodium Iodide","D012974",101,13,20,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C30,B30)","v":"Phenobarbital"},"Phenobarbital","D010634",96,33,98,323,48]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C31,B31)","v":"Vitamin D"},"Vitamin D","D014807",92,38,54,476,80]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C32,B32)","v":"Carbimazole"},"Carbimazole","D002231",91,381,133,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C33,B33)","v":"Minocycline"},"Minocycline","D008911",88,3,8,260,53]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C34,B34)","v":"potassium perchlorate"},"potassium perchlorate","C009006",87,40,25,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C35,B35)","v":"Prostaglandins E"},"Prostaglandins E","D011458",85,2,12,25,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C36,B36)","v":"Dopamine"},"Dopamine","D004298",83,46,153,4028,446]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C37,B37)","v":"Vitamin E"},"Vitamin E","D014810",82,36,63,419,43]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C38,B38)","v":"ammonium perchlorate"},"ammonium perchlorate","C053506",81,14,24,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C39,B39)","v":"Carbachol"},"Carbachol","D002217",81,2,6,558,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C40,B40)","v":"Reserpine"},"Reserpine","D012110",79,45,72,185,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C41,B41)","v":"Colforsin"},"Colforsin","D005576",79,5,6,228,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C42,B42)","v":"thiocyanate"},"thiocyanate","C031760",78,17,14,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C43,B43)","v":"Phenytoin"},"Phenytoin","D010672",76,29,123,326,89]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C44,B44)","v":"Blood Glucose"},"Blood Glucose","D001786",72,80,284,481,108]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C45,B45)","v":"Lithium Carbonate"},"Lithium Carbonate","D016651",71,48,42,105,36]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C46,B46)","v":"Tretinoin"},"Tretinoin","D014212",71,48,40,1501,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C47,B47)","v":"Fluorodeoxyglucose F18"},"Fluorodeoxyglucose F18","D019788",70,6,20,80,35]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C48,B48)","v":"Theophylline"},"Theophylline","D013806",69,15,34,178,24]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C49,B49)","v":"Isoproterenol"},"Isoproterenol","D007545",69,45,56,272,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C50,B50)","v":"Technetium Tc 99m Sestamibi"},"Technetium Tc 99m Sestamibi","D017256",69,3,14,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C51,B51)","v":"Vitamin B 12"},"Vitamin B 12","D014805",65,13,50,79,146]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C52,B52)","v":"Chlorpromazine"},"Chlorpromazine","D002746",65,18,32,205,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C53,B53)","v":"Histamine"},"Histamine","D006632",63,20,52,712,71]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C54,B54)","v":"Sodium Chloride"},"Sodium Chloride","D012965",63,19,40,201,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C55,B55)","v":"diisopropanolnitrosamine"},"diisopropanolnitrosamine","C012457",63,7,24,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C56,B56)","v":"Diethylstilbestrol"},"Diethylstilbestrol","D004054",62,11,64,121,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C57,B57)","v":"Iodized Oil"},"Iodized Oil","D007459",60,17,52,0,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C58,B58)","v":"Carbamazepine"},"Carbamazepine","D002220",59,33,74,362,129]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C59,B59)","v":"Water"},"Water","D014867",59,16,38,207,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C60,B60)","v":"Iopanoic Acid"},"Iopanoic Acid","D007480",59,46,76,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C61,B61)","v":"Calcitriol"},"Calcitriol","D002117",58,10,22,829,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C62,B62)","v":"Calcium, Dietary"},"Calcium, Dietary","D002136",57,12,32,52,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C63,B63)","v":"Acetylcholine"},"Acetylcholine","D000109",56,9,38,3470,126]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C64,B64)","v":"Povidone"},"Povidone","D011205",54,8,38,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C65,B65)","v":"bisphenol A"},"bisphenol A","C006780",52,24,38,384,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C66,B66)","v":"sunitinib"},"sunitinib","C473478",52,22,16,16,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C67,B67)","v":"Cholecalciferol"},"Cholecalciferol","D002762",52,10,20,166,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C68,B68)","v":"Phenylbutazone"},"Phenylbutazone","D010653",52,12,16,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C69,B69)","v":"Zineb"},"Zineb","D015038",52,13,13,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C70,B70)","v":"perfluorooctane sulfonic acid"},"perfluorooctane sulfonic acid","C076994",50,24,34,104,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C71,B71)","v":"DDT"},"DDT","D003634",49,10,20,33,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C72,B72)","v":"decabromobiphenyl ether"},"decabromobiphenyl ether","C010902",49,23,15,49,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C73,B73)","v":"Niacinamide"},"Niacinamide","D009536",48,9,10,122,33]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C74,B74)","v":"Prednisone"},"Prednisone","D011241",48,30,56,35,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C75,B75)","v":"Genistein"},"Genistein","D019833",48,17,6,233,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C76,B76)","v":"Amitrole"},"Amitrole","D000640",48,13,12,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C77,B77)","v":"Maneb"},"Maneb","D008344",47,9,11,17,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C78,B78)","v":"Hydroxypropiophenone"},"Hydroxypropiophenone","D006910",47,11,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C79,B79)","v":"Nitric Oxide"},"Nitric Oxide","D009569",46,33,26,2759,54]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C80,B80)","v":"Hexachlorobenzene"},"Hexachlorobenzene","D006581",46,15,26,7,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C81,B81)","v":"Metformin"},"Metformin","D008687",45,13,40,266,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C82,B82)","v":"2,2',4,4'-tetrabromodiphenyl ether"},"2,2',4,4'-tetrabromodiphenyl ether","C511295",45,25,19,40,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C83,B83)","v":"Aminosalicylic Acid"},"Aminosalicylic Acid","D010131",44,3,4,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C84,B84)","v":"Arachidonic Acid"},"Arachidonic Acid","D016718",43,3,0,417,23]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C85,B85)","v":"Triclosan"},"Triclosan","D014260",42,26,26,17,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C86,B86)","v":"Sodium Selenite"},"Sodium Selenite","D018038",41,34,10,51,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C87,B87)","v":"Indomethacin"},"Indomethacin","D007213",40,10,22,146,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C88,B88)","v":"Aspirin"},"Aspirin","D001241",38,12,30,221,52]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C89,B89)","v":"Chlorodiphenyl (54% Chlorine)"},"Chlorodiphenyl (54% Chlorine)","D020111",37,101,34,74,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C90,B90)","v":"Glucosamine"},"Glucosamine","D005944",37,2,4,76,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C91,B91)","v":"Dinoprostone"},"Dinoprostone","D015232",36,3,10,671,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C92,B92)","v":"sorafenib"},"sorafenib","C471405",35,5,12,12,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C93,B93)","v":"Sodium Fluoride"},"Sodium Fluoride","D012969",35,2,6,77,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C94,B94)","v":"Ethylenethiourea"},"Ethylenethiourea","D005031",35,7,18,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C95,B95)","v":"Urea"},"Urea","D014508",34,17,50,139,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C96,B96)","v":"Niacin"},"Niacin","D009525",34,5,25,43,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C97,B97)","v":"Iohexol"},"Iohexol","D007472",34,5,12,15,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C98,B98)","v":"Nicotine"},"Nicotine","D009538",33,20,12,1876,304]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C99,B99)","v":"Folic Acid"},"Folic Acid","D005492",33,11,51,245,162]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C100,B100)","v":"Diethylhexyl Phthalate"},"Diethylhexyl Phthalate","D004051",33,14,18,107,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C101,B101)","v":"Prednisolone"},"Prednisolone","D011239",33,31,84,66,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C102,B102)","v":"Cycloheximide"},"Cycloheximide","D003513",33,11,16,193,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C103,B103)","v":"Ouabain"},"Ouabain","D010042",33,15,20,189,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C104,B104)","v":"desethylamiodarone"},"desethylamiodarone","C036116",33,20,20,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C105,B105)","v":"kojic acid"},"kojic acid","C011890",33,3,8,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C106,B106)","v":"Diazepam"},"Diazepam","D003975",32,8,18,724,92]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C107,B107)","v":"3-methyl-4',6-dihydroxy-3',5'-dibromoflavone"},"3-methyl-4',6-dihydroxy-3',5'-dibromoflavone","C057452",32,30,16,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C108,B108)","v":"pentabromodiphenyl ether"},"pentabromodiphenyl ether","C086401",31,21,25,26,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C109,B109)","v":"Morphine"},"Morphine","D009020",30,7,26,1484,62]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C110,B110)","v":"Thiopental"},"Thiopental","D013874",30,0,14,110,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C111,B111)","v":"Cadmium Chloride"},"Cadmium Chloride","D019256",30,8,10,121,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C112,B112)","v":"6-iodo-5-hydroxy-eicosatrienoic acid, delta-lactone"},"6-iodo-5-hydroxy-eicosatrienoic acid, delta-lactone","C026915",30,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C113,B113)","v":"Carbon Tetrachloride"},"Carbon Tetrachloride","D002251",30,8,44,161,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C114,B114)","v":"Methylcholanthrene"},"Methylcholanthrene","D008748",30,7,29,42,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C115,B115)","v":"Imipramine"},"Imipramine","D007099",29,13,20,531,29]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C116,B116)","v":"4-hydroxypropiophenone"},"4-hydroxypropiophenone","C069170",29,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C117,B117)","v":"Sphingosine"},"Sphingosine","D013110",29,0,4,313,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C118,B118)","v":"Drinking Water"},"Drinking Water","D060766",28,2,4,19,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C119,B119)","v":"Norethynodrel"},"Norethynodrel","D009641",28,0,8,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C120,B120)","v":"Phentolamine"},"Phentolamine","D010646",28,7,12,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C121,B121)","v":"Prostaglandins F"},"Prostaglandins F","D011460",28,1,4,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C122,B122)","v":"Norethindrone"},"Norethindrone","D009640",27,4,10,21,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C123,B123)","v":"fenvalerate"},"fenvalerate","C017690",27,20,7,30,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C124,B124)","v":"dronedarone"},"dronedarone","C118667",27,6,8,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C125,B125)","v":"Tetracycline"},"Tetracycline","D013752",27,4,12,374,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C126,B126)","v":"Cyclophosphamide"},"Cyclophosphamide","D003520",26,15,14,102,23]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C127,B127)","v":"Uracil"},"Uracil","D014498",26,15,10,33,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C128,B128)","v":"Glycogen"},"Glycogen","D006003",26,21,98,121,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C129,B129)","v":"Caffeine"},"Caffeine","D002110",25,8,22,412,240]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C130,B130)","v":"Vitamin K"},"Vitamin K","D014812",25,9,18,27,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C131,B131)","v":"2,4,5,2',4',5'-hexachlorobiphenyl"},"2,4,5,2',4',5'-hexachlorobiphenyl","C014024",25,14,26,21,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C132,B132)","v":"Pentachlorophenol"},"Pentachlorophenol","D010416",25,8,22,11,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C133,B133)","v":"Clomiphene"},"Clomiphene","D002996",25,6,28,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C134,B134)","v":"mancozeb"},"mancozeb","C013099",25,9,9,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C135,B135)","v":"Sulfamethazine"},"Sulfamethazine","D013418",25,3,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C136,B136)","v":"Tamoxifen"},"Tamoxifen","D013629",24,13,26,263,39]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C137,B137)","v":"Isoniazid"},"Isoniazid","D007538",24,2,12,17,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C138,B138)","v":"Acrylamide"},"Acrylamide","D020106",24,1,4,46,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C139,B139)","v":"Atrazine"},"Atrazine","D001280",24,6,6,58,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C140,B140)","v":"potassium thiocyanate"},"potassium thiocyanate","C009941",24,11,10,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C141,B141)","v":"sulfanilamide"},"sulfanilamide","C036944",24,3,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C142,B142)","v":"Trimethoprim"},"Trimethoprim","D014295",24,3,8,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C143,B143)","v":"Valproic Acid"},"Valproic Acid","D014635",23,14,28,806,196]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C144,B144)","v":"Mercuric Chloride"},"Mercuric Chloride","D008627",23,11,12,73,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C145,B145)","v":"Calcimycin"},"Calcimycin","D000001",23,0,2,62,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C146,B146)","v":"Chlortetracycline"},"Chlortetracycline","D002751",23,5,4,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C147,B147)","v":"Perchloric Acid"},"Perchloric Acid","C576518",23,53,10,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C148,B148)","v":"Pregnenolone Carbonitrile"},"Pregnenolone Carbonitrile","D011285",23,7,19,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C149,B149)","v":"Halothane"},"Halothane","D006221",22,1,24,182,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C150,B150)","v":"Trimethoprim, Sulfamethoxazole Drug Combination"},"Trimethoprim, Sulfamethoxazole Drug Combination","D015662",22,1,13,1,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C151,B151)","v":"resveratrol"},"resveratrol","C059514",21,11,4,827,49]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C152,B152)","v":"Lithium Chloride"},"Lithium Chloride","D018021",21,6,8,391,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C153,B153)","v":"Apigenin"},"Apigenin","D047310",21,7,3,116,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C154,B154)","v":"Pentobarbital"},"Pentobarbital","D010424",21,9,14,462,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C155,B155)","v":"Epoprostenol"},"Epoprostenol","D011464",21,5,4,102,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C156,B156)","v":"2-iodohexadecanal"},"2-iodohexadecanal","C065952",21,5,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C157,B157)","v":"perfluorooctanoic acid"},"perfluorooctanoic acid","C023036",21,6,18,30,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C158,B158)","v":"Colchicine"},"Colchicine","D003078",20,3,12,339,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C159,B159)","v":"Creatinine"},"Creatinine","D003404",20,7,44,17,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C160,B160)","v":"Acetazolamide"},"Acetazolamide","D000086",20,1,2,33,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C161,B161)","v":"lead acetate"},"lead acetate","C008261",20,5,4,158,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C162,B162)","v":"Desipramine"},"Desipramine","D003891",20,18,31,316,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C163,B163)","v":"Methyltestosterone"},"Methyltestosterone","D008777",20,9,30,8,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C164,B164)","v":"3-Iodobenzylguanidine"},"3-Iodobenzylguanidine","D019797",20,5,6,3,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C165,B165)","v":"Alloxan"},"Alloxan","D000496",20,4,17,18,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C166,B166)","v":"Deoxyglucose"},"Deoxyglucose","D003847",20,9,20,273,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C167,B167)","v":"Metyrapone"},"Metyrapone","D008797",20,7,10,67,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C168,B168)","v":"3,4,5,3',4'-pentachlorobiphenyl"},"3,4,5,3',4'-pentachlorobiphenyl","C023035",20,12,23,37,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C169,B169)","v":"Edetic Acid"},"Edetic Acid","D004492",20,2,16,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C170,B170)","v":"Monensin"},"Monensin","D008985",20,1,4,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C171,B171)","v":"Tolbutamide"},"Tolbutamide","D014044",20,6,12,34,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C172,B172)","v":"Galactose"},"Galactose","D005690",19,0,8,248,57]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C173,B173)","v":"Thiamine"},"Thiamine","D013831",19,4,24,66,29]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C174,B174)","v":"25-hydroxyvitamin D"},"25-hydroxyvitamin D","C104450",19,14,22,24,26]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C175,B175)","v":"Sodium, Dietary"},"Sodium, Dietary","D012982",19,6,26,63,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C176,B176)","v":"Swainsonine"},"Swainsonine","D017026",19,4,0,10,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C177,B177)","v":"2,3',4,4',5-pentachlorobiphenyl"},"2,3',4,4',5-pentachlorobiphenyl","C070055",19,3,8,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C178,B178)","v":"Ether"},"Ether","D004986",19,2,4,32,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C179,B179)","v":"HBME-1 antigen"},"HBME-1 antigen","C432845",19,4,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C180,B180)","v":"Ipodate"},"Ipodate","D007487",19,7,60,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C181,B181)","v":"Lugol's solution"},"Lugol's solution","C010389",19,7,8,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C182,B182)","v":"Rose Bengal"},"Rose Bengal","D012395",19,11,8,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C183,B183)","v":"tetrabromobisphenol A"},"tetrabromobisphenol A","C020806",19,21,10,35,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C184,B184)","v":"Amphetamine"},"Amphetamine","D000661",18,12,23,554,57]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C185,B185)","v":"Bromocriptine"},"Bromocriptine","D001971",18,15,47,41,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C186,B186)","v":"rosiglitazone"},"rosiglitazone","C089730",18,1,4,389,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C187,B187)","v":"Phenylephrine"},"Phenylephrine","D010656",18,11,6,38,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C188,B188)","v":"Lindane"},"Lindane","D001556",18,3,8,62,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C189,B189)","v":"Aminoglutethimide"},"Aminoglutethimide","D000616",18,2,10,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C190,B190)","v":"Dithiothreitol"},"Dithiothreitol","D004229",18,15,8,32,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C191,B191)","v":"Freund's Adjuvant"},"Freund's Adjuvant","D005620",18,2,10,20,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C192,B192)","v":"Liver Glycogen"},"Liver Glycogen","D008112",18,10,64,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C193,B193)","v":"nonylphenol"},"nonylphenol","C025256",18,4,2,59,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C194,B194)","v":"Phenylthiourea"},"Phenylthiourea","D010670",18,14,10,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C195,B195)","v":"resorcinol"},"resorcinol","C031389",18,11,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C196,B196)","v":"Sulfamethoxazole"},"Sulfamethoxazole","D013420",18,3,4,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C197,B197)","v":"Trypan Blue"},"Trypan Blue","D014343",18,2,12,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C198,B198)","v":"Cisplatin"},"Cisplatin","D002945",17,3,8,275,23]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C199,B199)","v":"Thioctic Acid"},"Thioctic Acid","D008063",17,9,4,226,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C200,B200)","v":"Methylprednisolone"},"Methylprednisolone","D008775",17,18,26,141,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C201,B201)","v":"Lovastatin"},"Lovastatin","D008148",17,3,8,119,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C202,B202)","v":"Chlordiazepoxide"},"Chlordiazepoxide","D002707",17,1,2,116,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C203,B203)","v":"3,4,3',4'-tetrachlorobiphenyl"},"3,4,3',4'-tetrachlorobiphenyl","C028451",17,11,23,30,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C204,B204)","v":"Calcium Chloride"},"Calcium Chloride","D002122",17,2,8,22,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C205,B205)","v":"Erythrosine"},"Erythrosine","D004923",17,5,8,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C206,B206)","v":"hexabromocyclododecane"},"hexabromocyclododecane","C089796",17,12,8,20,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C207,B207)","v":"Methylnitrosourea"},"Methylnitrosourea","D008770",17,4,8,33,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C208,B208)","v":"Choline"},"Choline","D002794",16,4,12,1120,54]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C209,B209)","v":"Clonidine"},"Clonidine","D003000",16,2,10,136,30]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C210,B210)","v":"Carbon Dioxide"},"Carbon Dioxide","D002245",16,7,20,184,25]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C211,B211)","v":"Doxorubicin"},"Doxorubicin","D004317",16,9,14,287,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C212,B212)","v":"Methylene Blue"},"Methylene Blue","D008751",16,6,10,40,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C213,B213)","v":"fenclofenac"},"fenclofenac","C012970",16,1,18,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C214,B214)","v":"Furosemide"},"Furosemide","D005665",16,1,16,43,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C215,B215)","v":"Mannose"},"Mannose","D008358",16,0,0,28,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C216,B216)","v":"TK 12627"},"TK 12627","C066840",16,10,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C217,B217)","v":"pioglitazone"},"pioglitazone","C060836",15,2,0,254,27]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C218,B218)","v":"Ubiquinone"},"Ubiquinone","D014451",15,9,26,165,27]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C219,B219)","v":"Taurine"},"Taurine","D013654",15,7,14,609,23]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C220,B220)","v":"methylmercuric chloride"},"methylmercuric chloride","C004925",15,8,4,66,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C221,B221)","v":"Cysteamine"},"Cysteamine","D003543",15,4,4,74,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C222,B222)","v":"Heparin"},"Heparin","D006493",15,6,76,176,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C223,B223)","v":"Dinoprost"},"Dinoprost","D015237",15,2,10,148,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C224,B224)","v":"Levonorgestrel"},"Levonorgestrel","D016912",15,3,7,37,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C225,B225)","v":"G(M1) Ganglioside"},"G(M1) Ganglioside","D005677",15,0,2,235,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C226,B226)","v":"Dimethoate"},"Dimethoate","D004117",15,8,6,22,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C227,B227)","v":"Dimethyl Sulfoxide"},"Dimethyl Sulfoxide","D004121",15,3,2,128,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C228,B228)","v":"3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester"},"3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester","D001498",15,0,0,58,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C229,B229)","v":"Butylated Hydroxytoluene"},"Butylated Hydroxytoluene","D002084",15,0,2,20,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C230,B230)","v":"Chlorpropamide"},"Chlorpropamide","D002747",15,1,8,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C231,B231)","v":"Clofibrate"},"Clofibrate","D002994",15,7,40,20,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C232,B232)","v":"fipronil"},"fipronil","C082360",15,3,6,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C233,B233)","v":"goitrin"},"goitrin","C004333",15,27,8,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C234,B234)","v":"phenothiazine"},"phenothiazine","C031637",15,6,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C235,B235)","v":"Chlorpyrifos"},"Chlorpyrifos","D004390",14,5,18,157,32]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C236,B236)","v":"Cholesterol, Dietary"},"Cholesterol, Dietary","D002791",14,11,18,151,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C237,B237)","v":"Dichlorodiphenyl Dichloroethylene"},"Dichlorodiphenyl Dichloroethylene","D003633",14,11,12,23,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C238,B238)","v":"myricetin"},"myricetin","C040015",14,6,2,32,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C239,B239)","v":"Rifampin"},"Rifampin","D012293",14,8,18,49,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C240,B240)","v":"2,4-Dichlorophenoxyacetic Acid"},"2,4-Dichlorophenoxyacetic Acid","D015084",14,5,6,10,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C241,B241)","v":"Phloretin"},"Phloretin","D010693",14,5,2,15,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C242,B242)","v":"Potassium Cyanide"},"Potassium Cyanide","D011190",14,0,8,20,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C243,B243)","v":"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid"},"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid","D017878",14,4,0,19,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C244,B244)","v":"Inositol 1,4,5-Trisphosphate"},"Inositol 1,4,5-Trisphosphate","D015544",14,0,0,127,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C245,B245)","v":"iopromide"},"iopromide","C038192",14,3,8,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C246,B246)","v":"sphingosine 1-phosphate"},"sphingosine 1-phosphate","C060506",14,0,0,183,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C247,B247)","v":"Streptomycin"},"Streptomycin","D013307",14,3,6,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C248,B248)","v":"Sulfadimethoxine"},"Sulfadimethoxine","D013412",14,2,6,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C249,B249)","v":"triadimefon"},"triadimefon","C032910",14,5,2,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C250,B250)","v":"Fluoxetine"},"Fluoxetine","D005473",13,8,12,1070,58]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C251,B251)","v":"Inositol"},"Inositol","D007294",13,3,8,145,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C252,B252)","v":"Fluorouracil"},"Fluorouracil","D005472",13,2,6,69,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C253,B253)","v":"Spironolactone"},"Spironolactone","D013148",13,6,10,67,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C254,B254)","v":"Coal"},"Coal","D003031",13,8,2,13,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C255,B255)","v":"Dust"},"Dust","D004391",13,3,4,29,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C256,B256)","v":"Ketoconazole"},"Ketoconazole","D007654",13,4,4,18,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C257,B257)","v":"Glycerol"},"Glycerol","D005990",13,9,18,65,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C258,B258)","v":"Methallibure"},"Methallibure","D008693",13,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C259,B259)","v":"perfluorodecanoic acid"},"perfluorodecanoic acid","C036567",13,3,8,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C260,B260)","v":"potassium iodate"},"potassium iodate","C039693",13,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C261,B261)","v":"zinc chloride"},"zinc chloride","C016837",13,4,4,133,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C262,B262)","v":"Formaldehyde"},"Formaldehyde","D005557",12,0,2,170,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C263,B263)","v":"Procaine"},"Procaine","D011343",12,2,2,98,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C264,B264)","v":"Citric Acid"},"Citric Acid","D019343",12,3,4,13,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C265,B265)","v":"Permethrin"},"Permethrin","D026023",12,9,2,50,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C266,B266)","v":"Norgestrel"},"Norgestrel","D009644",12,4,4,7,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C267,B267)","v":"Petroleum"},"Petroleum","D010578",12,6,12,55,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C268,B268)","v":"Acetylglucosamine"},"Acetylglucosamine","D000117",12,1,0,91,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C269,B269)","v":"chlorine dioxide"},"chlorine dioxide","C025109",12,2,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C270,B270)","v":"hexamethylene bisacetamide"},"hexamethylene bisacetamide","C014026",12,0,0,31,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C271,B271)","v":"sodium bromide"},"sodium bromide","C027938",12,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C272,B272)","v":"Thapsigargin"},"Thapsigargin","D019284",12,0,0,61,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C273,B273)","v":"vitexin"},"vitexin","C032731",12,7,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C274,B274)","v":"Cocaine"},"Cocaine","D003042",11,5,7,1337,150]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C275,B275)","v":"Cimetidine"},"Cimetidine","D002927",11,6,18,24,75]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C276,B276)","v":"Catechin"},"Catechin","D002392",11,9,10,555,28]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C277,B277)","v":"Carnitine"},"Carnitine","D002331",11,17,38,165,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C278,B278)","v":"Pyridoxine"},"Pyridoxine","D011736",11,6,24,66,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C279,B279)","v":"Amiloride"},"Amiloride","D000584",11,1,4,67,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C280,B280)","v":"Iopamidol"},"Iopamidol","D007479",11,0,2,10,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C281,B281)","v":"beta Carotene"},"beta Carotene","D019207",11,4,12,70,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C282,B282)","v":"Carbofuran"},"Carbofuran","D002235",11,3,4,11,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C283,B283)","v":"phthalic acid"},"phthalic acid","C032279",11,8,8,17,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C284,B284)","v":"Omeprazole"},"Omeprazole","D009853",11,7,8,38,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C285,B285)","v":"2,2',4,4'-tetrahydroxybenzophenone"},"2,2',4,4'-tetrahydroxybenzophenone","C035476",11,9,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C286,B286)","v":"6-OH-BDE-47"},"6-OH-BDE-47","C580599",11,5,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C287,B287)","v":"6-propyl-2-selenouracil"},"6-propyl-2-selenouracil","C079082",11,8,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C288,B288)","v":"Carbaryl"},"Carbaryl","D012721",11,3,6,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C289,B289)","v":"Carbutamide"},"Carbutamide","D002271",11,0,6,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C290,B290)","v":"Diatrizoate"},"Diatrizoate","D003973",11,3,8,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C291,B291)","v":"Dolichol"},"Dolichol","D004286",11,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C292,B292)","v":"Paraffin"},"Paraffin","D010232",11,1,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C293,B293)","v":"potassium bromide"},"potassium bromide","C039004",11,2,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C294,B294)","v":"potassium nitrate"},"potassium nitrate","C023844",11,2,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C295,B295)","v":"salicylsalicylic acid"},"salicylsalicylic acid","C014182",11,3,16,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C296,B296)","v":"SK&F 93479"},"SK&F 93479","C033275",11,3,6,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C297,B297)","v":"Sulfadiazine"},"Sulfadiazine","D013411",11,4,12,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C298,B298)","v":"Technetium Tc 99m Medronate"},"Technetium Tc 99m Medronate","D013669",11,0,6,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C299,B299)","v":"technetium tc-99m tetrofosmin"},"technetium tc-99m tetrofosmin","C078700",11,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C300,B300)","v":"tributyltin"},"tributyltin","C011559",11,5,2,72,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C301,B301)","v":"Methadone"},"Methadone","D008691",10,3,14,35,59]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C302,B302)","v":"Tobacco Smoke Pollution"},"Tobacco Smoke Pollution","D014028",10,6,6,103,34]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C303,B303)","v":"Uric Acid"},"Uric Acid","D014527",10,5,24,79,33]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C304,B304)","v":"Heme"},"Heme","D006418",10,4,10,194,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C305,B305)","v":"Raloxifene Hydrochloride"},"Raloxifene Hydrochloride","D020849",10,0,12,80,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C306,B306)","v":"Antipyrine"},"Antipyrine","D000983",10,4,14,118,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C307,B307)","v":"Iron, Dietary"},"Iron, Dietary","D019266",10,6,2,38,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C308,B308)","v":"Lactic Acid"},"Lactic Acid","D019344",10,4,12,366,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C309,B309)","v":"Calcifediol"},"Calcifediol","D002112",10,11,8,47,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C310,B310)","v":"Disulfiram"},"Disulfiram","D004221",10,2,6,18,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C311,B311)","v":"Tacrolimus"},"Tacrolimus","D016559",10,3,2,318,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C312,B312)","v":"Warfarin"},"Warfarin","D014859",10,19,29,18,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C313,B313)","v":"Benzene"},"Benzene","D001554",10,0,2,41,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C314,B314)","v":"4-Aminobenzoic Acid"},"4-Aminobenzoic Acid","D010129",10,3,6,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C315,B315)","v":"Calcium Oxalate"},"Calcium Oxalate","D002129",10,0,0,15,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C316,B316)","v":"Industrial Waste"},"Industrial Waste","D007220",10,4,4,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C317,B317)","v":"Iproniazid"},"Iproniazid","D007490",10,5,6,22,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C318,B318)","v":"Isotretinoin"},"Isotretinoin","D015474",10,2,8,39,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C319,B319)","v":"leucomalachite green"},"leucomalachite green","C015320",10,5,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C320,B320)","v":"Mephobarbital"},"Mephobarbital","D008618",10,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C321,B321)","v":"Phenoxybenzamine"},"Phenoxybenzamine","D010643",10,3,8,16,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C322,B322)","v":"Sulfamonomethoxine"},"Sulfamonomethoxine","D013422",10,6,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C323,B323)","v":"Tyramine"},"Tyramine","D014439",10,1,12,34,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C324,B324)","v":"Urethane"},"Urethane","D014520",10,0,4,136,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C325,B325)","v":"Tea"},"Tea","D013662",9,7,4,166,36]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C326,B326)","v":"Heroin"},"Heroin","D003932",9,2,6,133,24]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C327,B327)","v":"Nifedipine"},"Nifedipine","D009543",9,3,13,143,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C328,B328)","v":"Mifepristone"},"Mifepristone","D015735",9,6,3,185,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C329,B329)","v":"Hydrochlorothiazide"},"Hydrochlorothiazide","D006852",9,6,0,6,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C330,B330)","v":"oxcarbazepine"},"oxcarbazepine","C036006",9,5,8,46,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C331,B331)","v":"Pilocarpine"},"Pilocarpine","D010862",9,2,4,839,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C332,B332)","v":"Diosgenin"},"Diosgenin","D004144",9,0,0,29,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C333,B333)","v":"daidzein"},"daidzein","C004742",9,2,6,75,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C334,B334)","v":"Gallic Acid"},"Gallic Acid","D005707",9,0,2,67,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C335,B335)","v":"Malathion"},"Malathion","D008294",9,1,2,59,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C336,B336)","v":"Medroxyprogesterone"},"Medroxyprogesterone","D008525",9,1,6,18,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C337,B337)","v":"Metronidazole"},"Metronidazole","D008795",9,2,4,7,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C338,B338)","v":"5-Methoxytryptamine"},"5-Methoxytryptamine","D008735",9,5,13,18,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C339,B339)","v":"Acetic Acid"},"Acetic Acid","D019342",9,0,6,38,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C340,B340)","v":"Desogestrel"},"Desogestrel","D017135",9,2,6,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C341,B341)","v":"Ethionamide"},"Ethionamide","D005000",9,2,2,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C342,B342)","v":"Biureas"},"Biureas","D001736",9,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C343,B343)","v":"Chlordan"},"Chlordan","D002706",9,0,2,5,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C344,B344)","v":"wortmannin"},"wortmannin","C009687",9,1,0,23,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C345,B345)","v":"xanthohumol"},"xanthohumol","C104536",9,8,2,22,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C346,B346)","v":"2,2',3,5',6-pentachlorobiphenyl"},"2,2',3,5',6-pentachlorobiphenyl","C032904",9,1,5,24,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C347,B347)","v":"2,4,4'-trichlorobiphenyl"},"2,4,4'-trichlorobiphenyl","C081766",9,2,4,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C348,B348)","v":"2-mercaptobenzimidazole"},"2-mercaptobenzimidazole","C030698",9,3,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C349,B349)","v":"3,3',5,5'-tetramethylbenzidine"},"3,3',5,5'-tetramethylbenzidine","C021758",9,8,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C350,B350)","v":"Chloramphenicol"},"Chloramphenicol","D002701",9,8,14,26,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C351,B351)","v":"Chloroquine"},"Chloroquine","D002738",9,8,10,78,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C352,B352)","v":"Cyclofenil"},"Cyclofenil","D003506",9,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C353,B353)","v":"Cystamine"},"Cystamine","D003538",9,2,0,22,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C354,B354)","v":"Danazol"},"Danazol","D003613",9,2,22,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C355,B355)","v":"Daunorubicin"},"Daunorubicin","D003630",9,0,0,19,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C356,B356)","v":"fipronil sulfone"},"fipronil sulfone","C534368",9,2,4,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C357,B357)","v":"Fucose"},"Fucose","D005643",9,2,6,88,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C358,B358)","v":"fucosyl GM1 ganglioside"},"fucosyl GM1 ganglioside","C039123",9,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C359,B359)","v":"Iodoacetic Acid"},"Iodoacetic Acid","D019807",9,9,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C360,B360)","v":"Mirex"},"Mirex","D008917",9,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C361,B361)","v":"nitrofen"},"nitrofen","C007350",9,3,4,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C362,B362)","v":"Pentetic Acid"},"Pentetic Acid","D004369",9,1,2,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C363,B363)","v":"Phosphorylcholine"},"Phosphorylcholine","D010767",9,1,0,36,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C364,B364)","v":"sodium nitrate"},"sodium nitrate","C031618",9,3,4,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C365,B365)","v":"sphingosine phosphorylcholine"},"sphingosine phosphorylcholine","C005356",9,0,0,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C366,B366)","v":"Sulfamoxole"},"Sulfamoxole","D013423",9,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C367,B367)","v":"Trimeprazine"},"Trimeprazine","D014291",9,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C368,B368)","v":"Isoflurane"},"Isoflurane","D007530",8,3,14,734,152]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C369,B369)","v":"Propofol"},"Propofol","D015742",8,2,2,609,114]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C370,B370)","v":"Toluene"},"Toluene","D014050",8,2,0,197,41]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C371,B371)","v":"Amitriptyline"},"Amitriptyline","D000639",8,7,6,122,29]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C372,B372)","v":"Metoclopramide"},"Metoclopramide","D008787",8,7,26,3,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C373,B373)","v":"Okadaic Acid"},"Okadaic Acid","D019319",8,0,0,165,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C374,B374)","v":"Metoprolol"},"Metoprolol","D008790",8,7,14,19,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C375,B375)","v":"Prazosin"},"Prazosin","D011224",8,6,2,36,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C376,B376)","v":"Vinblastine"},"Vinblastine","D014747",8,1,0,11,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C377,B377)","v":"fluorophosphate"},"fluorophosphate","C012980",8,0,2,4,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C378,B378)","v":"gluconic acid"},"gluconic acid","C030691",8,0,2,8,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C379,B379)","v":"Hyaluronic Acid"},"Hyaluronic Acid","D006820",8,2,12,313,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C380,B380)","v":"Inulin"},"Inulin","D007444",8,1,0,37,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C381,B381)","v":"naringenin"},"naringenin","C005273",8,5,0,57,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C382,B382)","v":"4,4'-hexafluorisopropylidene diphenol"},"4,4'-hexafluorisopropylidene diphenol","C583074",8,3,4,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C383,B383)","v":"Barbital"},"Barbital","D001462",8,0,2,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C384,B384)","v":"beta-Aminoethyl Isothiourea"},"beta-Aminoethyl Isothiourea","D000338",8,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C385,B385)","v":"biochanin A"},"biochanin A","C004541",8,5,0,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C386,B386)","v":"Chlorothiazide"},"Chlorothiazide","D002740",8,0,2,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C387,B387)","v":"Cholic Acid"},"Cholic Acid","D019826",8,4,8,18,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C388,B388)","v":"Cottonseed Oil"},"Cottonseed Oil","D003369",8,0,4,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C389,B389)","v":"cyhalothrin"},"cyhalothrin","C037304",8,4,2,37,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C390,B390)","v":"Dicumarol"},"Dicumarol","D001728",8,4,12,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C391,B391)","v":"Dimercaprol"},"Dimercaprol","D004112",8,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C392,B392)","v":"EMD 49209"},"EMD 49209","C103020",8,8,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C393,B393)","v":"FOE 5043"},"FOE 5043","C094127",8,4,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C394,B394)","v":"Heparitin Sulfate"},"Heparitin Sulfate","D006497",8,1,2,131,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C395,B395)","v":"inositol phosphate glycan"},"inositol phosphate glycan","C028039",8,4,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C396,B396)","v":"Latex"},"Latex","D007840",8,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C397,B397)","v":"Lipofuscin"},"Lipofuscin","D008062",8,0,0,65,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C398,B398)","v":"photomirex"},"photomirex","C016665",8,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C399,B399)","v":"Toxaphene"},"Toxaphene","D014112",8,2,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C400,B400)","v":"Carbon Monoxide"},"Carbon Monoxide","D002248",7,2,6,278,152]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C401,B401)","v":"Curcumin"},"Curcumin","D003474",7,7,10,773,63]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C402,B402)","v":"Dextroamphetamine"},"Dextroamphetamine","D003913",7,6,12,237,62]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C403,B403)","v":"Quercetin"},"Quercetin","D011794",7,7,6,441,35]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C404,B404)","v":"Sertraline"},"Sertraline","D020280",7,8,13,91,31]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C405,B405)","v":"Lidocaine"},"Lidocaine","D008012",7,0,6,251,21]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C406,B406)","v":"Pentylenetetrazole"},"Pentylenetetrazole","D010433",7,3,11,529,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C407,B407)","v":"Luteolin"},"Luteolin","D047311",7,4,0,112,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C408,B408)","v":"Methanol"},"Methanol","D000432",7,2,2,42,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C409,B409)","v":"Carbon Disulfide"},"Carbon Disulfide","D002246",7,1,14,24,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C410,B410)","v":"Meprobamate"},"Meprobamate","D008620",7,1,2,34,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C411,B411)","v":"Silicon Dioxide"},"Silicon Dioxide","D012822",7,0,2,142,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C412,B412)","v":"Alfaxalone Alfadolone Mixture"},"Alfaxalone Alfadolone Mixture","D000530",7,0,6,4,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C413,B413)","v":"Diazoxide"},"Diazoxide","D003981",7,0,0,100,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C414,B414)","v":"Parathion"},"Parathion","D010278",7,2,2,33,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C415,B415)","v":"Quinacrine"},"Quinacrine","D011796",7,0,2,20,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C416,B416)","v":"Adenine"},"Adenine","D000225",7,2,4,115,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C417,B417)","v":"cyanogen"},"cyanogen","C011206",7,6,2,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C418,B418)","v":"Diethylnitrosamine"},"Diethylnitrosamine","D004052",7,3,4,21,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C419,B419)","v":"imidacloprid"},"imidacloprid","C082359",7,1,4,12,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C420,B420)","v":"Methoxychlor"},"Methoxychlor","D008731",7,7,0,29,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C421,B421)","v":"14-iodo-15-hydroxyeicosatrienoic acid, omega lactone"},"14-iodo-15-hydroxyeicosatrienoic acid, omega lactone","C030074",7,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C422,B422)","v":"2,2',4,4',5-brominated diphenyl ether"},"2,2',4,4',5-brominated diphenyl ether","C477694",7,6,14,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C423,B423)","v":"2,4,6-tribromophenol"},"2,4,6-tribromophenol","C004554",7,5,6,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C424,B424)","v":"2-Acetylaminofluorene"},"2-Acetylaminofluorene","D015073",7,2,4,25,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C425,B425)","v":"4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid"},"4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid","D012856",7,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C426,B426)","v":"acetochlor"},"acetochlor","C043377",7,6,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C427,B427)","v":"alachlor"},"alachlor","C000188",7,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C428,B428)","v":"Calcium Gluconate"},"Calcium Gluconate","D002125",7,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C429,B429)","v":"chloramine-T"},"chloramine-T","C016300",7,3,4,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C430,B430)","v":"diethyl phthalate"},"diethyl phthalate","C007379",7,2,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C431,B431)","v":"Erythromycin"},"Erythromycin","D004917",7,5,0,45,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C432,B432)","v":"Ethiodized Oil"},"Ethiodized Oil","D004998",7,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C433,B433)","v":"glucosylorientin"},"glucosylorientin","C058774",7,5,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C434,B434)","v":"glucosylvitexin"},"glucosylvitexin","C058773",7,5,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C435,B435)","v":"Methysergide"},"Methysergide","D008784",7,2,4,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C436,B436)","v":"monobutyl phthalate"},"monobutyl phthalate","C028577",7,1,4,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C437,B437)","v":"N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide"},"N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide","C063509",7,0,0,130,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C438,B438)","v":"N,N'-methylene-bis(2-amino-5-sulfhydryl-1,3,4-thiadiazole)"},"N,N'-methylene-bis(2-amino-5-sulfhydryl-1,3,4-thiadiazole)","C044397",7,4,6,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C439,B439)","v":"N-acetylsphingosine"},"N-acetylsphingosine","C064769",7,0,0,27,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C440,B440)","v":"Orotic Acid"},"Orotic Acid","D009963",7,4,12,48,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C441,B441)","v":"Phorbol 12,13-Dibutyrate"},"Phorbol 12,13-Dibutyrate","D015240",7,0,0,142,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C442,B442)","v":"sodium chlorate"},"sodium chlorate","C032706",7,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C443,B443)","v":"Staurosporine"},"Staurosporine","D019311",7,0,0,113,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C444,B444)","v":"triclocarban"},"triclocarban","C009540",7,7,0,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C445,B445)","v":"Xylazine"},"Xylazine","D014991",7,1,6,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C446,B446)","v":"Ketamine"},"Ketamine","D007649",6,0,6,929,183]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C447,B447)","v":"Simvastatin"},"Simvastatin","D019821",6,1,16,312,41]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C448,B448)","v":"Coffee"},"Coffee","D003069",6,4,12,25,30]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C449,B449)","v":"Amobarbital"},"Amobarbital","D000654",6,0,8,90,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C450,B450)","v":"Atropine"},"Atropine","D001285",6,4,12,394,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C451,B451)","v":"Fluvoxamine"},"Fluvoxamine","D016666",6,2,2,58,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C452,B452)","v":"Digoxin"},"Digoxin","D004077",6,11,38,23,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C453,B453)","v":"Verapamil"},"Verapamil","D014700",6,1,14,125,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C454,B454)","v":"Aminophylline"},"Aminophylline","D000628",6,3,6,22,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C455,B455)","v":"1-Deoxynojirimycin"},"1-Deoxynojirimycin","D017485",6,2,0,15,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C456,B456)","v":"clobazam"},"clobazam","C012255",6,1,4,6,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C457,B457)","v":"Doxycycline"},"Doxycycline","D004318",6,0,2,215,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C458,B458)","v":"piperine"},"piperine","C008922",6,8,3,57,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C459,B459)","v":"Primidone"},"Primidone","D011324",6,1,4,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C460,B460)","v":"Theobromine"},"Theobromine","D013805",6,3,0,29,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C461,B461)","v":"arsenic trioxide"},"arsenic trioxide","C006632",6,8,4,80,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C462,B462)","v":"Diclofenac"},"Diclofenac","D004008",6,1,8,58,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C463,B463)","v":"Digitoxin"},"Digitoxin","D004074",6,3,8,6,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C464,B464)","v":"Mycophenolic Acid"},"Mycophenolic Acid","D009173",6,0,0,67,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C465,B465)","v":"Orphenadrine"},"Orphenadrine","D009966",6,2,10,12,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C466,B466)","v":"Platelet Activating Factor"},"Platelet Activating Factor","D010972",6,2,0,246,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C467,B467)","v":"salicylanilide"},"salicylanilide","C034596",6,0,0,4,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C468,B468)","v":"Trifluoperazine"},"Trifluoperazine","D014268",6,0,2,69,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C469,B469)","v":"zoledronic acid"},"zoledronic acid","C088658",6,0,2,30,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C470,B470)","v":"Etodolac"},"Etodolac","D017308",6,0,6,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C471,B471)","v":"Levamisole"},"Levamisole","D007978",6,3,2,18,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C472,B472)","v":"manganese chloride"},"manganese chloride","C025340",6,1,4,53,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C473,B473)","v":"Nitrendipine"},"Nitrendipine","D009568",6,1,4,30,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C474,B474)","v":"2,2',4,4',5-pentachlorodiphenyl ether"},"2,2',4,4',5-pentachlorodiphenyl ether","C058905",6,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C475,B475)","v":"2,4,2',4'-tetrachlorobiphenyl"},"2,4,2',4'-tetrachlorobiphenyl","C035976",6,0,4,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C476,B476)","v":"2,4,5,2',5'-pentachlorobiphenyl"},"2,4,5,2',5'-pentachlorobiphenyl","C009828",6,0,9,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C477,B477)","v":"2-amino-5-nitrothiazole"},"2-amino-5-nitrothiazole","C034870",6,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C478,B478)","v":"4-methoxy-3-phenylenediamine"},"4-methoxy-3-phenylenediamine","C007294",6,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C479,B479)","v":"4-nonylphenol"},"4-nonylphenol","C041594",6,3,8,27,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C480,B480)","v":"4-tert-octylphenol"},"4-tert-octylphenol","C105260",6,0,0,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C481,B481)","v":"5,8,11,14-Eicosatetraynoic Acid"},"5,8,11,14-Eicosatetraynoic Acid","D015117",6,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C482,B482)","v":"5-nitrothiazole"},"5-nitrothiazole","C581042",6,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C483,B483)","v":"8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate"},"8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate","C006014",6,0,0,16,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C484,B484)","v":"Acrylonitrile"},"Acrylonitrile","D000181",6,0,0,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C485,B485)","v":"beta-Naphthoflavone"},"beta-Naphthoflavone","D019324",6,5,4,23,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C486,B486)","v":"bis(4-hydroxyphenyl)sulfone"},"bis(4-hydroxyphenyl)sulfone","C543008",6,2,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C487,B487)","v":"butachlor"},"butachlor","C054409",6,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C488,B488)","v":"Butylated Hydroxyanisole"},"Butylated Hydroxyanisole","D002083",6,2,2,15,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C489,B489)","v":"calyculin A"},"calyculin A","C059041",6,0,0,30,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C490,B490)","v":"castanospermine"},"castanospermine","C037806",6,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C491,B491)","v":"ceramide 1-phosphate"},"ceramide 1-phosphate","C065576",6,0,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C492,B492)","v":"chlorite"},"chlorite","C001599",6,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C493,B493)","v":"Cyanamide"},"Cyanamide","D003484",6,6,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C494,B494)","v":"Cytochalasin B"},"Cytochalasin B","D003571",6,0,0,17,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C495,B495)","v":"Deoxycholic Acid"},"Deoxycholic Acid","D003840",6,4,2,26,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C496,B496)","v":"Diatrizoate Meglumine"},"Diatrizoate Meglumine","D003974",6,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C497,B497)","v":"dibenzofuran"},"dibenzofuran","C023614",6,0,4,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C498,B498)","v":"Dibutyl Phthalate"},"Dibutyl Phthalate","D003993",6,1,0,40,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C499,B499)","v":"Dienestrol"},"Dienestrol","D004028",6,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C500,B500)","v":"Dimethylformamide"},"Dimethylformamide","D004126",6,0,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C501,B501)","v":"Endosulfan"},"Endosulfan","D004726",6,3,2,30,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C502,B502)","v":"ethylenediamine"},"ethylenediamine","C031234",6,0,2,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C503,B503)","v":"Etretinate"},"Etretinate","D005050",6,4,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C504,B504)","v":"Fluocortolone"},"Fluocortolone","D005448",6,3,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C505,B505)","v":"Fluprednisolone"},"Fluprednisolone","D005477",6,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C506,B506)","v":"Gossypol"},"Gossypol","D006072",6,3,8,18,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C507,B507)","v":"hexadecafluoro-nonanoic acid"},"hexadecafluoro-nonanoic acid","C018959",6,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C508,B508)","v":"Heymann Nephritis Antigenic Complex"},"Heymann Nephritis Antigenic Complex","D026541",6,2,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C509,B509)","v":"Hydrochloric Acid"},"Hydrochloric Acid","D006851",6,0,2,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C510,B510)","v":"Iodohippuric Acid"},"Iodohippuric Acid","D007465",6,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C511,B511)","v":"iomeprol"},"iomeprol","C057937",6,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C512,B512)","v":"iotrolan"},"iotrolan","C033300",6,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C513,B513)","v":"Ioxaglic Acid"},"Ioxaglic Acid","D007485",6,1,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C514,B514)","v":"ioxynil"},"ioxynil","C008161",6,2,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C515,B515)","v":"ipriflavone"},"ipriflavone","C018986",6,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C516,B516)","v":"Linuron"},"Linuron","D008044",6,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C517,B517)","v":"malachite green"},"malachite green","C005095",6,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C518,B518)","v":"methanandamide"},"methanandamide","C088155",6,0,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C519,B519)","v":"Methane"},"Methane","D008697",6,2,0,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C520,B520)","v":"Methoxyflurane"},"Methoxyflurane","D008733",6,0,4,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C521,B521)","v":"metolachlor"},"metolachlor","C051786",6,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C522,B522)","v":"mezerein"},"mezerein","C011309",6,0,0,17,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C523,B523)","v":"Monocrotophos"},"Monocrotophos","D008999",6,3,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C524,B524)","v":"NCGC00242364"},"NCGC00242364","C586517",6,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C525,B525)","v":"N-vinyl-2-pyrrolidinone"},"N-vinyl-2-pyrrolidinone","C042670",6,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C526,B526)","v":"Oxytetracycline"},"Oxytetracycline","D010118",6,0,6,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C527,B527)","v":"p-Dimethylaminoazobenzene"},"p-Dimethylaminoazobenzene","D004124",6,0,10,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C528,B528)","v":"perfluorohexanesulfonic acid"},"perfluorohexanesulfonic acid","C471071",6,3,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C529,B529)","v":"phorbol-12,13-didecanoate"},"phorbol-12,13-didecanoate","C008876",6,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C530,B530)","v":"Phosphatidylinositol 4,5-Diphosphate"},"Phosphatidylinositol 4,5-Diphosphate","D019269",6,2,2,93,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C531,B531)","v":"Polyvinyl Alcohol"},"Polyvinyl Alcohol","D011142",6,0,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C532,B532)","v":"Potassium Dichromate"},"Potassium Dichromate","D011192",6,1,4,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C533,B533)","v":"pregna-4,17-diene-3,16-dione"},"pregna-4,17-diene-3,16-dione","C023617",6,0,0,19,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C534,B534)","v":"pyridine"},"pyridine","C023666",6,5,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C535,B535)","v":"Rose Bengal B"},"Rose Bengal B","C048837",6,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C536,B536)","v":"Silicic Acid"},"Silicic Acid","D012824",6,1,2,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C537,B537)","v":"sodium arsenate"},"sodium arsenate","C009277",6,1,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C538,B538)","v":"temelastine"},"temelastine","C049054",6,1,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C539,B539)","v":"temiverine"},"temiverine","C105354",6,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C540,B540)","v":"thiobarbituric acid"},"thiobarbituric acid","C029684",6,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C541,B541)","v":"Thiophanate"},"Thiophanate","D013875",6,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C542,B542)","v":"Triamcinolone"},"Triamcinolone","D014221",6,2,14,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C543,B543)","v":"tris(1,3-dichloro-2-propyl)phosphate"},"tris(1,3-dichloro-2-propyl)phosphate","C016805",6,5,6,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C544,B544)","v":"W 7"},"W 7","C017967",6,0,2,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C545,B545)","v":"Waste Water"},"Waste Water","D062065",6,1,2,29,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C546,B546)","v":"Zeranol"},"Zeranol","D015029",6,3,4,33,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C547,B547)","v":"Lysergic Acid Diethylamide"},"Lysergic Acid Diethylamide","D008238",5,1,6,114,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C548,B548)","v":"Sirolimus"},"Sirolimus","D020123",5,1,2,434,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C549,B549)","v":"Berberine"},"Berberine","D001599",5,3,8,235,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C550,B550)","v":"Saline Solution, Hypertonic"},"Saline Solution, Hypertonic","D012462",5,1,2,61,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C551,B551)","v":"25-Hydroxyvitamin D 2"},"25-Hydroxyvitamin D 2","D015652",5,5,0,2,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C552,B552)","v":"Nialamide"},"Nialamide","D009526",5,0,2,8,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C553,B553)","v":"Sewage"},"Sewage","D012722",5,1,0,16,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C554,B554)","v":"sodium arsenite"},"sodium arsenite","C017947",5,4,2,129,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C555,B555)","v":"Bilirubin"},"Bilirubin","D001663",5,6,36,76,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C556,B556)","v":"Iothalamic Acid"},"Iothalamic Acid","D007483",5,0,2,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C557,B557)","v":"Styrene"},"Styrene","D020058",5,2,2,20,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C558,B558)","v":"Ketoprofen"},"Ketoprofen","D007660",5,0,2,14,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C559,B559)","v":"Meglumine"},"Meglumine","D008536",5,2,2,29,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C560,B560)","v":"2,2',4,4',5,6'-hexabromodiphenyl ether"},"2,2',4,4',5,6'-hexabromodiphenyl ether","C555859",5,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C561,B561)","v":"6-anilino-2-thiouracil"},"6-anilino-2-thiouracil","C099649",5,4,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C562,B562)","v":"Acetaldehyde"},"Acetaldehyde","D000079",5,0,2,82,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C563,B563)","v":"Adrenochrome"},"Adrenochrome","D000323",5,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C564,B564)","v":"benzyl isothiocyanate"},"benzyl isothiocyanate","C031403",5,2,2,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C565,B565)","v":"carbendazim"},"carbendazim","C006698",5,3,2,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C566,B566)","v":"Centchroman"},"Centchroman","D002486",5,3,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C567,B567)","v":"coumarin"},"coumarin","C030123",5,4,2,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C568,B568)","v":"Diamide"},"Diamide","D003958",5,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C569,B569)","v":"Dianisidine"},"Dianisidine","D003962",5,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C570,B570)","v":"Dihydrotachysterol"},"Dihydrotachysterol","D004097",5,1,14,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C571,B571)","v":"flufenoxuron"},"flufenoxuron","C067660",5,3,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C572,B572)","v":"Guanine"},"Guanine","D006147",5,2,2,77,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C573,B573)","v":"Hexamethonium"},"Hexamethonium","D018738",5,0,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C574,B574)","v":"Indocyanine Green"},"Indocyanine Green","D007208",5,3,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C575,B575)","v":"Mercaptoethanol"},"Mercaptoethanol","D008623",5,0,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C576,B576)","v":"Mercaptopurine"},"Mercaptopurine","D015122",5,7,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C577,B577)","v":"NCGC 00229600"},"NCGC 00229600","C556685",5,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C578,B578)","v":"Phenindione"},"Phenindione","D010630",5,2,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C579,B579)","v":"potassium bromate"},"potassium bromate","C019536",5,0,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C580,B580)","v":"purine"},"purine","C030985",5,0,4,16,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C581,B581)","v":"Pyridoxal Phosphate"},"Pyridoxal Phosphate","D011732",5,4,24,60,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C582,B582)","v":"Succinylcholine"},"Succinylcholine","D013390",5,0,2,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C583,B583)","v":"Sulfaguanidine"},"Sulfaguanidine","D013414",5,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C584,B584)","v":"Tolonium Chloride"},"Tolonium Chloride","D014048",5,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C585,B585)","v":"Methylphenidate"},"Methylphenidate","D008774",4,2,10,190,260]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C586,B586)","v":"Methamphetamine"},"Methamphetamine","D008694",4,1,2,868,199]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C587,B587)","v":"Haloperidol"},"Haloperidol","D006220",4,7,10,632,127]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C588,B588)","v":"Streptozocin"},"Streptozocin","D013311",4,0,8,216,49]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C589,B589)","v":"Fentanyl"},"Fentanyl","D005283",4,1,4,50,40]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C590,B590)","v":"Ranitidine"},"Ranitidine","D011899",4,8,4,11,36]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C591,B591)","v":"Nitrous Oxide"},"Nitrous Oxide","D009609",4,2,4,68,34]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C592,B592)","v":"Naloxone"},"Naloxone","D009270",4,2,6,229,32]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C593,B593)","v":"Metrizamide"},"Metrizamide","D008793",4,0,0,20,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C594,B594)","v":"Vitamin B 6"},"Vitamin B 6","D025101",4,1,4,24,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C595,B595)","v":"Naproxen"},"Naproxen","D009288",4,2,4,9,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C596,B596)","v":"Trichlorfon"},"Trichlorfon","D014236",4,0,0,52,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C597,B597)","v":"Acetaminophen"},"Acetaminophen","D000082",4,3,10,160,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C598,B598)","v":"alpha-Tocopherol"},"alpha-Tocopherol","D024502",4,6,2,157,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C599,B599)","v":"Thimerosal"},"Thimerosal","D013849",4,6,0,22,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C600,B600)","v":"Enflurane"},"Enflurane","D004737",4,0,6,46,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C601,B601)","v":"Flurbiprofen"},"Flurbiprofen","D005480",4,0,2,30,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C602,B602)","v":"Sucrose"},"Sucrose","D013395",4,4,10,83,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C603,B603)","v":"Thalidomide"},"Thalidomide","D013792",4,13,6,86,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C604,B604)","v":"Promethazine"},"Promethazine","D011398",4,0,2,4,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C605,B605)","v":"Clomipramine"},"Clomipramine","D002997",4,3,14,92,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C606,B606)","v":"Fenofibrate"},"Fenofibrate","D011345",4,2,0,123,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C607,B607)","v":"N-Acetylneuraminic Acid"},"N-Acetylneuraminic Acid","D019158",4,1,10,44,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C608,B608)","v":"Riboflavin"},"Riboflavin","D012256",4,5,18,20,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C609,B609)","v":"tanespimycin"},"tanespimycin","C112765",4,0,0,18,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C610,B610)","v":"1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine"},"1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307",4,0,2,163,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C611,B611)","v":"ABO Blood-Group System"},"ABO Blood-Group System","D000017",4,0,2,45,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C612,B612)","v":"Camphor"},"Camphor","D002164",4,1,4,8,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C613,B613)","v":"Cholestyramine Resin"},"Cholestyramine Resin","D002792",4,11,30,9,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C614,B614)","v":"Codeine"},"Codeine","D003061",4,0,0,14,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C615,B615)","v":"Dapsone"},"Dapsone","D003622",4,4,2,14,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C616,B616)","v":"Etidronic Acid"},"Etidronic Acid","D012968",4,1,2,8,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C617,B617)","v":"Gadolinium DTPA"},"Gadolinium DTPA","D019786",4,0,0,22,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C618,B618)","v":"Ifosfamide"},"Ifosfamide","D007069",4,1,2,6,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C619,B619)","v":"Methoxamine"},"Methoxamine","D008729",4,1,4,8,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C620,B620)","v":"N-acetylserotonin"},"N-acetylserotonin","C006389",4,0,2,14,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C621,B621)","v":"Pargyline"},"Pargyline","D010293",4,1,2,13,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C622,B622)","v":"Quinine"},"Quinine","D011803",4,3,4,27,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C623,B623)","v":"Cyproheptadine"},"Cyproheptadine","D003533",4,0,14,13,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C624,B624)","v":"Mescaline"},"Mescaline","D008635",4,0,0,6,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C625,B625)","v":"Mitotane"},"Mitotane","D008939",4,1,8,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C626,B626)","v":"Ozone"},"Ozone","D010126",4,3,10,130,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C627,B627)","v":"Perphenazine"},"Perphenazine","D010546",4,3,8,12,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C628,B628)","v":"Rotenone"},"Rotenone","D012402",4,0,6,86,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C629,B629)","v":"1,7-dimethylxanthine"},"1,7-dimethylxanthine","C021183",4,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C630,B630)","v":"14-iodo-15-hydroxy-5,8,11-eicosatrienoic acid"},"14-iodo-15-hydroxy-5,8,11-eicosatrienoic acid","C055893",4,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C631,B631)","v":"2,6-dichloro-4-nitrophenol"},"2,6-dichloro-4-nitrophenol","C015802",4,4,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C632,B632)","v":"24,25-Dihydroxyvitamin D 3"},"24,25-Dihydroxyvitamin D 3","D015650",4,0,4,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C633,B633)","v":"3-aminobenzamide"},"3-aminobenzamide","C025160",4,0,0,20,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C634,B634)","v":"6-methyl-2-selenouracil"},"6-methyl-2-selenouracil","C079083",4,4,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C635,B635)","v":"8,11,14-Eicosatrienoic Acid"},"8,11,14-Eicosatrienoic Acid","D015126",4,0,0,47,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C636,B636)","v":"Acenocoumarol"},"Acenocoumarol","D000074",4,1,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C637,B637)","v":"alitretinoin"},"alitretinoin","C103303",4,3,2,69,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C638,B638)","v":"allylthiourea"},"allylthiourea","C009842",4,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C639,B639)","v":"Alprenolol"},"Alprenolol","D000526",4,0,10,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C640,B640)","v":"Aminopropionitrile"},"Aminopropionitrile","D000629",4,0,4,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C641,B641)","v":"Antimony Potassium Tartrate"},"Antimony Potassium Tartrate","D000966",4,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C642,B642)","v":"barbituric acid"},"barbituric acid","C032232",4,0,2,16,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C643,B643)","v":"benziodarone"},"benziodarone","C058702",4,1,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C644,B644)","v":"bis(tri-n-butyltin)oxide"},"bis(tri-n-butyltin)oxide","C005961",4,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C645,B645)","v":"Chondroitin"},"Chondroitin","D002807",4,2,8,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C646,B646)","v":"Coal Tar"},"Coal Tar","D003033",4,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C647,B647)","v":"cyclopropane"},"cyclopropane","C030797",4,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C648,B648)","v":"Cyproterone"},"Cyproterone","D003534",4,1,10,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C649,B649)","v":"Dibenzylchlorethamine"},"Dibenzylchlorethamine","D003983",4,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C650,B650)","v":"Dichlorodiphenyldichloroethane"},"Dichlorodiphenyldichloroethane","D003632",4,0,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C651,B651)","v":"Diethyl Pyrocarbonate"},"Diethyl Pyrocarbonate","D004047",4,4,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C652,B652)","v":"dihydrolipoamide"},"dihydrolipoamide","C007409",4,4,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C653,B653)","v":"Fenoprofen"},"Fenoprofen","D005279",4,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C654,B654)","v":"Fluorescein"},"Fluorescein","D019793",4,0,4,15,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C655,B655)","v":"haizao yuhu"},"haizao yuhu","C560811",4,1,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C656,B656)","v":"Imatinib Mesylate"},"Imatinib Mesylate","D000068877",4,1,4,64,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C657,B657)","v":"Iodoacetamide"},"Iodoacetamide","D007460",4,4,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C658,B658)","v":"Iodopyracet"},"Iodopyracet","D007468",4,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C659,B659)","v":"isothiocyanic acid"},"isothiocyanic acid","C037152",4,7,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C660,B660)","v":"KT 5823"},"KT 5823","C073601",4,0,2,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C661,B661)","v":"Leucogenenol"},"Leucogenenol","D007932",4,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C662,B662)","v":"Methandriol"},"Methandriol","D008695",4,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C663,B663)","v":"Methandrostenolone"},"Methandrostenolone","D008696",4,4,6,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C664,B664)","v":"Methyl Parathion"},"Methyl Parathion","D008743",4,1,4,25,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C665,B665)","v":"norethindrone acetate"},"norethindrone acetate","C024262",4,1,2,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C666,B666)","v":"Octopamine"},"Octopamine","D009655",4,0,2,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C667,B667)","v":"Oleic Acid"},"Oleic Acid","D019301",4,1,26,123,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C668,B668)","v":"Oxyphenbutazone"},"Oxyphenbutazone","D010113",4,4,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C669,B669)","v":"phenyl methimazole"},"phenyl methimazole","C489637",4,4,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C670,B670)","v":"Phlorhizin"},"Phlorhizin","D010695",4,4,4,15,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C671,B671)","v":"p-Methoxy-N-methylphenethylamine"},"p-Methoxy-N-methylphenethylamine","D003189",4,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C672,B672)","v":"polidocanol"},"polidocanol","C008976",4,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C673,B673)","v":"Polyphloretin Phosphate"},"Polyphloretin Phosphate","D011121",4,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C674,B674)","v":"Probenecid"},"Probenecid","D011339",4,0,0,20,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C675,B675)","v":"Propyl Gallate"},"Propyl Gallate","D011435",4,4,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C676,B676)","v":"pyrimidine"},"pyrimidine","C030986",4,0,2,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C677,B677)","v":"Simazine"},"Simazine","D012839",4,0,2,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C678,B678)","v":"tetramethylthiourea"},"tetramethylthiourea","C019107",4,6,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C679,B679)","v":"Tetramisole"},"Tetramisole","D013773",4,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C680,B680)","v":"Thioacetazone"},"Thioacetazone","D013828",4,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C681,B681)","v":"Triamcinolone Acetonide"},"Triamcinolone Acetonide","D014222",4,0,0,33,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C682,B682)","v":"Triethylenemelamine"},"Triethylenemelamine","D014265",4,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C683,B683)","v":"Trimethaphan"},"Trimethaphan","D014294",4,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C684,B684)","v":"troglitazone"},"troglitazone","C057693",4,0,0,144,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C685,B685)","v":"Xylose"},"Xylose","D014994",4,0,4,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C686,B686)","v":"ZAMI 1305"},"ZAMI 1305","C028475",4,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C687,B687)","v":"N-Methyl-3,4-methylenedioxyamphetamine"},"N-Methyl-3,4-methylenedioxyamphetamine","D018817",3,0,6,583,250]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C688,B688)","v":"Dronabinol"},"Dronabinol","D013759",3,0,4,472,154]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C689,B689)","v":"Physostigmine"},"Physostigmine","D010830",3,0,0,265,64]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C690,B690)","v":"Midazolam"},"Midazolam","D008874",3,1,6,167,47]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C691,B691)","v":"Mianserin"},"Mianserin","D008803",3,1,4,102,25]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C692,B692)","v":"Sulpiride"},"Sulpiride","D013469",3,3,4,35,25]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C693,B693)","v":"Dental Amalgam"},"Dental Amalgam","D003723",3,2,2,0,24]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C694,B694)","v":"mirtazapine"},"mirtazapine","C035133",3,1,2,56,23]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C695,B695)","v":"vinpocetine"},"vinpocetine","C013983",3,1,0,54,23]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C696,B696)","v":"Temazepam"},"Temazepam","D013693",3,0,0,4,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C697,B697)","v":"Cotinine"},"Cotinine","D003367",3,3,2,22,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C698,B698)","v":"Gasoline"},"Gasoline","D005742",3,0,2,15,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C699,B699)","v":"Buspirone"},"Buspirone","D002065",3,0,0,144,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C700,B700)","v":"Naltrexone"},"Naltrexone","D009271",3,0,4,127,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C701,B701)","v":"ferulic acid"},"ferulic acid","C004999",3,1,4,87,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C702,B702)","v":"Clioquinol"},"Clioquinol","D007464",3,1,2,26,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C703,B703)","v":"Paraquat"},"Paraquat","D010269",3,2,0,131,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C704,B704)","v":"Pyridostigmine Bromide"},"Pyridostigmine Bromide","D011729",3,0,4,32,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C705,B705)","v":"Ethylene Oxide"},"Ethylene Oxide","D005027",3,0,0,0,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C706,B706)","v":"Malondialdehyde"},"Malondialdehyde","D008315",3,7,8,38,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C707,B707)","v":"Betamethasone"},"Betamethasone","D001623",3,11,56,73,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C708,B708)","v":"Glycyrrhizic Acid"},"Glycyrrhizic Acid","D019695",3,0,0,64,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C709,B709)","v":"Nitrogen Dioxide"},"Nitrogen Dioxide","D009585",3,1,0,14,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C710,B710)","v":"3,4-Methylenedioxyamphetamine"},"3,4-Methylenedioxyamphetamine","D015104",3,0,2,122,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C711,B711)","v":"alpha-Linolenic Acid"},"alpha-Linolenic Acid","D017962",3,0,0,74,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C712,B712)","v":"anandamide"},"anandamide","C078814",3,0,2,252,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C713,B713)","v":"Ergotamine"},"Ergotamine","D004878",3,1,4,4,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C714,B714)","v":"ferrous sulfate"},"ferrous sulfate","C020748",3,0,10,14,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C715,B715)","v":"Glyburide"},"Glyburide","D005905",3,2,10,70,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C716,B716)","v":"Rutin"},"Rutin","D012431",3,3,4,65,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C717,B717)","v":"Ammonia"},"Ammonia","D000641",3,6,18,168,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C718,B718)","v":"Arecoline"},"Arecoline","D001115",3,0,6,49,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C719,B719)","v":"Diazinon"},"Diazinon","D003976",3,0,2,26,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C720,B720)","v":"docetaxel"},"docetaxel","C067311",3,0,2,11,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C721,B721)","v":"Fludrocortisone"},"Fludrocortisone","D005438",3,0,2,2,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C722,B722)","v":"Maprotiline"},"Maprotiline","D008376",3,1,4,22,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C723,B723)","v":"Neostigmine"},"Neostigmine","D009388",3,3,4,69,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C724,B724)","v":"Soil"},"Soil","D012987",3,2,0,17,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C725,B725)","v":"Vincristine"},"Vincristine","D014750",3,0,2,30,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C726,B726)","v":"Zinc Oxide"},"Zinc Oxide","D015034",3,0,0,63,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C727,B727)","v":"Nevirapine"},"Nevirapine","D019829",3,0,0,6,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C728,B728)","v":"3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol"},"3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol","C054649",3,0,0,30,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C729,B729)","v":"Liuwei Dihuang Decoction"},"Liuwei Dihuang Decoction","C042579",3,0,2,41,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C730,B730)","v":"Measles-Mumps-Rubella Vaccine"},"Measles-Mumps-Rubella Vaccine","D022542",3,2,0,4,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C731,B731)","v":"Pentazocine"},"Pentazocine","D010423",3,0,0,16,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C732,B732)","v":"Pimozide"},"Pimozide","D010868",3,0,2,8,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C733,B733)","v":"Spermidine"},"Spermidine","D013095",3,0,2,131,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C734,B734)","v":"1-Propanol"},"1-Propanol","D000433",3,0,0,4,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C735,B735)","v":"Acarbose"},"Acarbose","D020909",3,0,2,18,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C736,B736)","v":"Allopurinol"},"Allopurinol","D000493",3,0,4,45,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C737,B737)","v":"bexarotene"},"bexarotene","C095105",3,2,20,33,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C738,B738)","v":"Dipyrone"},"Dipyrone","D004177",3,3,0,4,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C739,B739)","v":"fluorene"},"fluorene","C041509",3,0,0,2,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C740,B740)","v":"Flutamide"},"Flutamide","D005485",3,0,2,56,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C741,B741)","v":"imidazole"},"imidazole","C029899",3,8,4,7,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C742,B742)","v":"ioflupane"},"ioflupane","C519528",3,0,0,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C743,B743)","v":"JM 3100"},"JM 3100","C088327",3,0,0,26,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C744,B744)","v":"Kanamycin"},"Kanamycin","D007612",3,0,6,11,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C745,B745)","v":"Linoleic Acid"},"Linoleic Acid","D019787",3,0,4,60,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C746,B746)","v":"lithium sulfate"},"lithium sulfate","C054097",3,0,0,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C747,B747)","v":"Meclizine"},"Meclizine","D008468",3,0,2,2,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C748,B748)","v":"Nitroprusside"},"Nitroprusside","D009599",3,0,4,78,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C749,B749)","v":"Novobiocin"},"Novobiocin","D009675",3,0,4,10,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C750,B750)","v":"pamidronate"},"pamidronate","C019248",3,2,8,10,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C751,B751)","v":"pyrazolanthrone"},"pyrazolanthrone","C432165",3,0,0,36,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C752,B752)","v":"Salicylic Acid"},"Salicylic Acid","D020156",3,2,4,35,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C753,B753)","v":"Sodium Bicarbonate"},"Sodium Bicarbonate","D017693",3,0,2,5,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C754,B754)","v":"sulforafan"},"sulforafan","C016766",3,1,0,77,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C755,B755)","v":"Terbutaline"},"Terbutaline","D013726",3,4,4,17,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C756,B756)","v":"1-(2-pyrimidinyl)piperazine"},"1-(2-pyrimidinyl)piperazine","C037921",3,0,0,8,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C757,B757)","v":"arsenite"},"arsenite","C015001",3,1,0,110,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C758,B758)","v":"BCG Vaccine"},"BCG Vaccine","D001500",3,0,4,40,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C759,B759)","v":"Cromolyn Sodium"},"Cromolyn Sodium","D004205",3,0,0,4,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C760,B760)","v":"dibenzo(1,4)dioxin"},"dibenzo(1,4)dioxin","C020887",3,1,0,2,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C761,B761)","v":"endotoxin, Escherichia coli"},"endotoxin, Escherichia coli","C044101",3,3,0,40,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C762,B762)","v":"Equol"},"Equol","D060754",3,2,2,30,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C763,B763)","v":"fenproporex"},"fenproporex","C026013",3,1,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C764,B764)","v":"Ganciclovir"},"Ganciclovir","D015774",3,0,0,8,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C765,B765)","v":"Lincomycin"},"Lincomycin","D008034",3,0,0,1,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C766,B766)","v":"methylparaben"},"methylparaben","C015358",3,0,2,3,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C767,B767)","v":"methylxanthine"},"methylxanthine","C008514",3,0,0,2,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C768,B768)","v":"Palm Oil"},"Palm Oil","D000073878",3,0,0,4,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C769,B769)","v":"Phloroglucinol"},"Phloroglucinol","D010696",3,0,0,62,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C770,B770)","v":"Pindolol"},"Pindolol","D010869",3,4,2,80,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C771,B771)","v":"Piperonyl Butoxide"},"Piperonyl Butoxide","D010882",3,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C772,B772)","v":"vorinostat"},"vorinostat","C111237",3,1,2,66,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C773,B773)","v":"VX"},"VX","C009680",3,0,3,8,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C774,B774)","v":"zotepine"},"zotepine","C022172",3,1,0,2,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C775,B775)","v":"(4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid"},"(4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid","C461658",3,3,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C776,B776)","v":"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"},"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","C516138",3,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C777,B777)","v":"1-(4-bromophenyl)-5-mercapto-1,2,3,4-tetrazole"},"1-(4-bromophenyl)-5-mercapto-1,2,3,4-tetrazole","C070843",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C778,B778)","v":"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione"},"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione","C060229",3,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C779,B779)","v":"1-(diiodomethyl)sulfonyl-4-methyl benzene"},"1-(diiodomethyl)sulfonyl-4-methyl benzene","C076281",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C780,B780)","v":"1,2,3,4-tetrachlorobenzene"},"1,2,3,4-tetrachlorobenzene","C030386",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C781,B781)","v":"1,2,3,5-tetrachlorobenzene"},"1,2,3,5-tetrachlorobenzene","C030387",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C782,B782)","v":"1,2,4,5-tetrachlorobenzene"},"1,2,4,5-tetrachlorobenzene","C018673",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C783,B783)","v":"1,25-dihydroxyvitamin D"},"1,25-dihydroxyvitamin D","C097949",3,2,4,54,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C784,B784)","v":"1,2-diacylglycerol"},"1,2-diacylglycerol","C011439",3,0,4,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C785,B785)","v":"1,3-diethylbenzene"},"1,3-diethylbenzene","C064749",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C786,B786)","v":"1,3-dipropyl-8-cyclopentylxanthine"},"1,3-dipropyl-8-cyclopentylxanthine","C051360",3,1,2,52,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C787,B787)","v":"1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid"},"1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid","C071349",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C788,B788)","v":"1,4-diethoxybutane"},"1,4-diethoxybutane","C488840",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C789,B789)","v":"1,6-bis(cyclohexyloximinocarbonyl)hexane"},"1,6-bis(cyclohexyloximinocarbonyl)hexane","C036535",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C790,B790)","v":"1,6-dimethoxyhexane"},"1,6-dimethoxyhexane","C488841",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C791,B791)","v":"12-Hydroxy-5,8,10,14-eicosatetraenoic Acid"},"12-Hydroxy-5,8,10,14-eicosatetraenoic Acid","D019377",3,0,0,20,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C792,B792)","v":"13-hydroperoxy-9,11-octadecadienoic acid"},"13-hydroperoxy-9,11-octadecadienoic acid","C038649",3,1,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C793,B793)","v":"15-hydroxy-5,8,11,13-eicosatetraenoic acid"},"15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984",3,0,0,22,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C794,B794)","v":"1-Butanol"},"1-Butanol","D020001",3,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C795,B795)","v":"1-chloro-4-(chloromethyl)benzene"},"1-chloro-4-(chloromethyl)benzene","C576340",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C796,B796)","v":"1-methyl-3-propylimidazole-2-thione"},"1-methyl-3-propylimidazole-2-thione","C097373",3,3,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C797,B797)","v":"1-oleoyl-2-acetylglycerol"},"1-oleoyl-2-acetylglycerol","C038237",3,0,0,18,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C798,B798)","v":"2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine"},"2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine","C413491",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C799,B799)","v":"2-(3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro(1,2,4)triazine-6-carbonitrile"},"2-(3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro(1,2,4)triazine-6-carbonitrile","C588408",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C800,B800)","v":"2,2',3,3',4,6'-hexachlorodiphenyl ether"},"2,2',3,3',4,6'-hexachlorodiphenyl ether","C062112",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C801,B801)","v":"2,2',3,4,4',6,6'-heptachlorodiphenyl ether"},"2,2',3,4,4',6,6'-heptachlorodiphenyl ether","C065304",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C802,B802)","v":"2,2',4,4',5,5'-hexachlorodiphenyl ether"},"2,2',4,4',5,5'-hexachlorodiphenyl ether","C065303",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C803,B803)","v":"2,2',4,4',5,6-hexachlorodiphenyl ether"},"2,2',4,4',5,6-hexachlorodiphenyl ether","C062111",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C804,B804)","v":"2,2',4,4',6-pentachlorodiphenyl ether"},"2,2',4,4',6-pentachlorodiphenyl ether","C062110",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C805,B805)","v":"2,2'-Dipyridyl"},"2,2'-Dipyridyl","D015082",3,0,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C806,B806)","v":"2,3,3',4,4'-pentachlorobiphenyl"},"2,3,3',4,4'-pentachlorobiphenyl","C067940",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C807,B807)","v":"2,3,4,2',3',4'-hexachlorobiphenyl"},"2,3,4,2',3',4'-hexachlorobiphenyl","C014218",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C808,B808)","v":"2,3,5,6-tetrachlorohydroquinone"},"2,3,5,6-tetrachlorohydroquinone","C044578",3,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C809,B809)","v":"2,3-dihydroxypyridine"},"2,3-dihydroxypyridine","C035877",3,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C810,B810)","v":"2,4,4',5-tetrachlorobiphenyl"},"2,4,4',5-tetrachlorobiphenyl","C541132",3,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C811,B811)","v":"2,6-xylidine"},"2,6-xylidine","C007766",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C812,B812)","v":"2-ethoxyethanol"},"2-ethoxyethanol","C021296",3,1,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C813,B813)","v":"2-heptylchlorin dicarboxylic acid"},"2-heptylchlorin dicarboxylic acid","C106122",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C814,B814)","v":"2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt"},"2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt","C049774",3,2,2,74,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C815,B815)","v":"2-isopropylphenyl-N-methylcarbamate"},"2-isopropylphenyl-N-methylcarbamate","C526767",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C816,B816)","v":"2-mercaptomethylbenzimidazole"},"2-mercaptomethylbenzimidazole","C406304",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C817,B817)","v":"3-((3,5-dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid"},"3-((3,5-dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid","C526273",3,4,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C818,B818)","v":"3,4-methylenedioxyphenethylamine"},"3,4-methylenedioxyphenethylamine","C016575",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C819,B819)","v":"3-amino-5-mercapto-1,2,4-triazole"},"3-amino-5-mercapto-1,2,4-triazole","C488155",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C820,B820)","v":"3-aminophenol"},"3-aminophenol","C055528",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C821,B821)","v":"3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone"},"3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone","C054121",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C822,B822)","v":"3-heptylchlorin bisamidoglucose"},"3-heptylchlorin bisamidoglucose","C106123",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C823,B823)","v":"4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)pyrazolo(1,5-a)pyrimidine"},"4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)pyrazolo(1,5-a)pyrimidine","C417190",3,0,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C824,B824)","v":"4,4'-(octahydro-4,7-methano-5H-inden-5-ylidene)bisphenol"},"4,4'-(octahydro-4,7-methano-5H-inden-5-ylidene)bisphenol","C558701",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C825,B825)","v":"4,4'-diaminodiphenylmethane"},"4,4'-diaminodiphenylmethane","C009505",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C826,B826)","v":"4,4'-methylenebis(N,N'-dimethyl)aniline"},"4,4'-methylenebis(N,N'-dimethyl)aniline","C574620",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C827,B827)","v":"4-bromotetramisole"},"4-bromotetramisole","C006226",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C828,B828)","v":"4-chlorobenzo(f)isoquinoline"},"4-chlorobenzo(f)isoquinoline","C495450",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C829,B829)","v":"4-dichlorobenzene"},"4-dichlorobenzene","C018511",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C830,B830)","v":"4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide"},"4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide","C498826",3,1,0,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C831,B831)","v":"4-nitrophenyl beta-D-xyloside"},"4-nitrophenyl beta-D-xyloside","C008646",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C832,B832)","v":"5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride"},"5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride","C439425",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C833,B833)","v":"5-ethylidene-2-norbornene"},"5-ethylidene-2-norbornene","C108262",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C834,B834)","v":"6-heptyne-2,5-diamine"},"6-heptyne-2,5-diamine","C039613",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C835,B835)","v":"6-Ketoprostaglandin F1 alpha"},"6-Ketoprostaglandin F1 alpha","D015121",3,1,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C836,B836)","v":"7-(2-(2,2-difluoroethoxy)-3,5-di-tert-butylbenzene)-3-methylocta-2,4,6-trienoic acid"},"7-(2-(2,2-difluoroethoxy)-3,5-di-tert-butylbenzene)-3-methylocta-2,4,6-trienoic acid","C508470",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C837,B837)","v":"9,10-Dimethyl-1,2-benzanthracene"},"9,10-Dimethyl-1,2-benzanthracene","D015127",3,2,10,36,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C838,B838)","v":"9-fluoroprednisolone"},"9-fluoroprednisolone","C010958",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C839,B839)","v":"aceclofenac"},"aceclofenac","C056498",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C840,B840)","v":"Acepromazine"},"Acepromazine","D000075",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C841,B841)","v":"Acetohexamide"},"Acetohexamide","D000092",3,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C842,B842)","v":"Acetrizoic Acid"},"Acetrizoic Acid","D000100",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C843,B843)","v":"acylcarnitine"},"acylcarnitine","C116917",3,3,4,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C844,B844)","v":"Aldrin"},"Aldrin","D000452",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C845,B845)","v":"Allethrin"},"Allethrin","D000487",3,0,0,18,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C846,B846)","v":"allyl alcohol"},"allyl alcohol","C006463",3,2,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C847,B847)","v":"alpha-isomethylionone"},"alpha-isomethylionone","C494862",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C848,B848)","v":"Alprostadil"},"Alprostadil","D000527",3,1,0,58,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C849,B849)","v":"aluminum lactate"},"aluminum lactate","C104223",3,0,2,20,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C850,B850)","v":"Aminopyrine"},"Aminopyrine","D000632",3,5,10,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C851,B851)","v":"amphenone B"},"amphenone B","C073262",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C852,B852)","v":"Amphotericin B"},"Amphotericin B","D000666",3,0,0,29,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C853,B853)","v":"Antimycin A"},"Antimycin A","D000968",3,0,4,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C854,B854)","v":"Aphidicolin"},"Aphidicolin","D016590",3,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C855,B855)","v":"aroclor 1242"},"aroclor 1242","C027423",3,1,8,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C856,B856)","v":"aroclor 1260"},"aroclor 1260","C026987",3,1,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C857,B857)","v":"arotinolol"},"arotinolol","C024523",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C858,B858)","v":"arsenic acid"},"arsenic acid","C025657",3,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C859,B859)","v":"asphalt"},"asphalt","C006647",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C860,B860)","v":"AWD 131-138"},"AWD 131-138","C116306",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C861,B861)","v":"axitinib"},"axitinib","C503983",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C862,B862)","v":"BE 2254"},"BE 2254","C010652",3,1,4,18,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C863,B863)","v":"Benperidol"},"Benperidol","D001544",3,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C864,B864)","v":"benzidine"},"benzidine","C029876",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C865,B865)","v":"beta1-meconial antigen"},"beta1-meconial antigen","C063420",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C866,B866)","v":"betadex"},"betadex","C031215",3,0,0,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C867,B867)","v":"beta-hexachlorocyclohexane"},"beta-hexachlorocyclohexane","C023888",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C868,B868)","v":"bis(2-amino-5-sulfhydryl-1,3,4-thiadiazole)zinc(II)"},"bis(2-amino-5-sulfhydryl-1,3,4-thiadiazole)zinc(II)","C000606707",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C869,B869)","v":"bismerthiazol"},"bismerthiazol","C000608952",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C870,B870)","v":"bismerthlazol"},"bismerthlazol","C538720",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C871,B871)","v":"bisphenol A glucuronide"},"bisphenol A glucuronide","C512161",3,1,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C872,B872)","v":"Bumetanide"},"Bumetanide","D002034",3,0,0,54,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C873,B873)","v":"butylate"},"butylate","C023898",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C874,B874)","v":"butylphen"},"butylphen","C006862",3,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C875,B875)","v":"BXL628"},"BXL628","C487049",3,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C876,B876)","v":"cabozantinib"},"cabozantinib","C558660",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C877,B877)","v":"cafestol"},"cafestol","C053400",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C878,B878)","v":"calcipotriene"},"calcipotriene","C055085",3,0,0,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C879,B879)","v":"calystegin"},"calystegin","C055033",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C880,B880)","v":"Canrenoic Acid"},"Canrenoic Acid","D002191",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C881,B881)","v":"Carbadox"},"Carbadox","D002218",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C882,B882)","v":"carbene"},"carbene","C030011",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C883,B883)","v":"Carmine"},"Carmine","D002329",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C884,B884)","v":"carprofen"},"carprofen","C007005",3,0,2,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C885,B885)","v":"catechol"},"catechol","C034221",3,2,4,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C886,B886)","v":"cefpirome"},"cefpirome","C038950",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C887,B887)","v":"Celiprolol"},"Celiprolol","D017272",3,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C888,B888)","v":"Cellophane"},"Cellophane","D002476",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C889,B889)","v":"Cellulose"},"Cellulose","D002482",3,0,12,26,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C890,B890)","v":"Cereclor"},"Cereclor","C485044",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C891,B891)","v":"chloramine"},"chloramine","C030816",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C892,B892)","v":"chlorethylclonidine"},"chlorethylclonidine","C051731",3,0,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C893,B893)","v":"Chlorhexidine"},"Chlorhexidine","D002710",3,1,6,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C894,B894)","v":"chlorhexidine gluconate"},"chlorhexidine gluconate","C010882",3,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C895,B895)","v":"chloroquine diphosphate"},"chloroquine diphosphate","C023676",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C896,B896)","v":"chlorpyrifos-methyl"},"chlorpyrifos-methyl","C007031",3,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C897,B897)","v":"Cinanserin"},"Cinanserin","D002928",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C898,B898)","v":"Clodronic Acid"},"Clodronic Acid","D004002",3,0,0,23,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C899,B899)","v":"clophen A60"},"clophen A60","C042166",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C900,B900)","v":"clopyralid"},"clopyralid","C011767",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C901,B901)","v":"closantel"},"closantel","C023342",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C902,B902)","v":"Copper Sulfate"},"Copper Sulfate","D019327",3,1,2,62,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C903,B903)","v":"Curare"},"Curare","D003472",3,0,2,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C904,B904)","v":"CVT 2759"},"CVT 2759","C419102",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C905,B905)","v":"cyanopindolol"},"cyanopindolol","C047975",3,0,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C906,B906)","v":"cyclopiazonic acid"},"cyclopiazonic acid","C000543",3,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C907,B907)","v":"d,d-T80-prallethrin"},"d,d-T80-prallethrin","C055818",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C908,B908)","v":"Dasatinib"},"Dasatinib","D000069439",3,0,0,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C909,B909)","v":"decamethrin"},"decamethrin","C017180",3,2,0,174,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C910,B910)","v":"deethylatrazine"},"deethylatrazine","C446541",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C911,B911)","v":"deflazacort"},"deflazacort","C021988",3,1,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C912,B912)","v":"di-(4-aminophenyl)ether"},"di-(4-aminophenyl)ether","C015126",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C913,B913)","v":"dibromoacetonitrile"},"dibromoacetonitrile","C051715",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C914,B914)","v":"dibutyldichlorotin"},"dibutyldichlorotin","C020735",3,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C915,B915)","v":"diethofencarb"},"diethofencarb","C070961",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C916,B916)","v":"Diethylpropion"},"Diethylpropion","D004053",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C917,B917)","v":"Dihydrostreptomycin Sulfate"},"Dihydrostreptomycin Sulfate","D004096",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C918,B918)","v":"di-n-butyltin"},"di-n-butyltin","C056189",3,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C919,B919)","v":"diphenyl"},"diphenyl","C010574",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C920,B920)","v":"diphenylthiohydantoin"},"diphenylthiohydantoin","C073336",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C921,B921)","v":"direct blue 15"},"direct blue 15","C035549",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C922,B922)","v":"dithane M-45"},"dithane M-45","C011453",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C923,B923)","v":"dopexamine"},"dopexamine","C046318",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C924,B924)","v":"dotatate gallium ga-68"},"dotatate gallium ga-68","C513399",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C925,B925)","v":"Dowex"},"Dowex","C027972",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C926,B926)","v":"droloxifene"},"droloxifene","C038345",3,1,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C927,B927)","v":"dysidenin"},"dysidenin","C063771",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C928,B928)","v":"enterotoxin B, staphylococcal"},"enterotoxin B, staphylococcal","C031818",3,0,0,50,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C929,B929)","v":"enzacamene"},"enzacamene","C038939",3,1,2,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C930,B930)","v":"enzastaurin"},"enzastaurin","C504878",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C931,B931)","v":"ertiprotafib"},"ertiprotafib","C498182",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C932,B932)","v":"Ethacridine"},"Ethacridine","D004975",3,3,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C933,B933)","v":"Ethane"},"Ethane","D004980",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C934,B934)","v":"ethane sulfonate"},"ethane sulfonate","C002634",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C935,B935)","v":"Ethidium"},"Ethidium","D004996",3,0,0,22,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C936,B936)","v":"Ethylenebis(dithiocarbamates)"},"Ethylenebis(dithiocarbamates)","D005028",3,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C937,B937)","v":"etonogestrel"},"etonogestrel","C044815",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C938,B938)","v":"Fenitrothion"},"Fenitrothion","D005278",3,1,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C939,B939)","v":"fenoxycarb"},"fenoxycarb","C052034",3,1,2,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C940,B940)","v":"Filipin"},"Filipin","D005372",3,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C941,B941)","v":"Firemaster BP-6"},"Firemaster BP-6","C015885",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C942,B942)","v":"flumorph"},"flumorph","C528737",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C943,B943)","v":"Fluoxymesterone"},"Fluoxymesterone","D005474",3,2,5,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C944,B944)","v":"fructofuranosyl-(2-2)-fructofuranosyl"},"fructofuranosyl-(2-2)-fructofuranosyl","C000588575",3,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C945,B945)","v":"fulvic acid"},"fulvic acid","C005023",3,0,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C946,B946)","v":"Furazolidone"},"Furazolidone","D005664",3,0,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C947,B947)","v":"gadodiamide"},"gadodiamide","C064925",3,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C948,B948)","v":"Galactosamine"},"Galactosamine","D005688",3,1,0,38,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C949,B949)","v":"galaxolide"},"galaxolide","C033119",3,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C950,B950)","v":"ganglioside, GD1a"},"ganglioside, GD1a","C021298",3,0,0,13,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C951,B951)","v":"ganglioside, GD1b"},"ganglioside, GD1b","C033851",3,0,0,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C952,B952)","v":"ganglioside, GD3"},"ganglioside, GD3","C026226",3,0,0,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C953,B953)","v":"geneserine"},"geneserine","C060406",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C954,B954)","v":"gibberellic acid"},"gibberellic acid","C007842",3,0,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C955,B955)","v":"glucoraphanin"},"glucoraphanin","C119494",3,1,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C956,B956)","v":"Glutaral"},"Glutaral","D005976",3,2,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C957,B957)","v":"Glutethimide"},"Glutethimide","D005984",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C958,B958)","v":"glycovir"},"glycovir","C096960",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C959,B959)","v":"gossypol acetic acid"},"gossypol acetic acid","C028178",3,1,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C960,B960)","v":"green 5"},"green 5","C024537",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C961,B961)","v":"guggulu extract"},"guggulu extract","C018562",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C962,B962)","v":"hexaconazole"},"hexaconazole","C409722",3,0,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C963,B963)","v":"Histidinol"},"Histidinol","D006641",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C964,B964)","v":"hydracrylonitrile"},"hydracrylonitrile","C004914",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C965,B965)","v":"Hydrogen Cyanide"},"Hydrogen Cyanide","D006856",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C966,B966)","v":"Indophenol"},"Indophenol","D007215",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C967,B967)","v":"inositol-1,3,4,5-tetrakisphosphate"},"inositol-1,3,4,5-tetrakisphosphate","C081655",3,0,0,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C968,B968)","v":"iodinated glycerol"},"iodinated glycerol","C015372",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C969,B969)","v":"iodothiouracil"},"iodothiouracil","C036667",3,4,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C970,B970)","v":"ipsapirone"},"ipsapirone","C043077",3,0,0,82,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C971,B971)","v":"Iron-Dextran Complex"},"Iron-Dextran Complex","D007505",3,0,0,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C972,B972)","v":"kahweol"},"kahweol","C053401",3,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C973,B973)","v":"kaliotoxin"},"kaliotoxin","C072276",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C974,B974)","v":"kangjia"},"kangjia","C545319",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C975,B975)","v":"KC 500"},"KC 500","C477388",3,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C976,B976)","v":"Kerosene"},"Kerosene","D007648",3,0,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C977,B977)","v":"KN 62"},"KN 62","C063302",3,0,2,52,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C978,B978)","v":"kolaviron"},"kolaviron","C045492",3,1,0,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C979,B979)","v":"KT 5926"},"KT 5926","C063769",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C980,B980)","v":"L 649923"},"L 649923","C050033",3,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C981,B981)","v":"Lasalocid"},"Lasalocid","D007832",3,0,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C982,B982)","v":"lecithin-bound iodine"},"lecithin-bound iodine","C036559",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C983,B983)","v":"leontoside"},"leontoside","C047367",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C984,B984)","v":"LG 101208"},"LG 101208","C533893",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C985,B985)","v":"lithium citrate"},"lithium citrate","C070669",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C986,B986)","v":"Lynestrenol"},"Lynestrenol","D008234",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C987,B987)","v":"Malononitrile dimer"},"Malononitrile dimer","C025201",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C988,B988)","v":"Mannomustine"},"Mannomustine","D008357",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C989,B989)","v":"Measles Vaccine"},"Measles Vaccine","D008458",3,2,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C990,B990)","v":"Medazepam"},"Medazepam","D008472",3,0,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C991,B991)","v":"Megestrol"},"Megestrol","D008535",3,0,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C992,B992)","v":"meloxicam"},"meloxicam","C065757",3,0,2,30,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C993,B993)","v":"Methacholine Chloride"},"Methacholine Chloride","D016210",3,0,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C994,B994)","v":"methfuroxam"},"methfuroxam","C097392",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C995,B995)","v":"methyl tert-butyl ether"},"methyl tert-butyl ether","C043243",3,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C996,B996)","v":"metsulfuron methyl"},"metsulfuron methyl","C050296",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C997,B997)","v":"Mevalonic Acid"},"Mevalonic Acid","D008798",3,1,4,28,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C998,B998)","v":"mevastatin"},"mevastatin","C012258",3,0,0,29,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C999,B999)","v":"Mitoguazone"},"Mitoguazone","D008935",3,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1000,B1000)","v":"mono-(2-ethylhexyl)phthalate"},"mono-(2-ethylhexyl)phthalate","C016599",3,2,2,23,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1001,B1001)","v":"Mumps Vaccine"},"Mumps Vaccine","D009108",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1002,B1002)","v":"N(1)-methylnicotinamide"},"N(1)-methylnicotinamide","C024058",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1003,B1003)","v":"N-(2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl)-alpha,alpha,alpha-trifluoro-o-toluamide"},"N-(2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl)-alpha,alpha,alpha-trifluoro-o-toluamide","C572868",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1004,B1004)","v":"N-(2-guanidinoethyl)-5-isoquinolinesulfonamide"},"N-(2-guanidinoethyl)-5-isoquinolinesulfonamide","C043204",3,0,2,26,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1005,B1005)","v":"N-(4-(3-((4-fluorophenyl)hydroxymethyl)-4-hydroxyphenoxy)-3,5-dimethylphenyl) malonamic acid sodium"},"N-(4-(3-((4-fluorophenyl)hydroxymethyl)-4-hydroxyphenoxy)-3,5-dimethylphenyl) malonamic acid sodium","C496199",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1006,B1006)","v":"N-(6-aminohexyl)-1-naphthalenesulfonamide"},"N-(6-aminohexyl)-1-naphthalenesulfonamide","C034700",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1007,B1007)","v":"N,N-bis-(2-hydroxyethyl)-4-phenylenediamine"},"N,N-bis-(2-hydroxyethyl)-4-phenylenediamine","C050768",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1008,B1008)","v":"nabam"},"nabam","C005270",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1009,B1009)","v":"Nadolol"},"Nadolol","D009248",3,4,16,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1010,B1010)","v":"naphtha"},"naphtha","C004544",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1011,B1011)","v":"N-caproylsphingosine"},"N-caproylsphingosine","C101954",3,0,0,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1012,B1012)","v":"Nelfinavir"},"Nelfinavir","D019888",3,1,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1013,B1013)","v":"Neopterin"},"Neopterin","D019798",3,4,4,16,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1014,B1014)","v":"neurotropin"},"neurotropin","C010491",3,1,0,21,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1015,B1015)","v":"nitrobenzene"},"nitrobenzene","C036077",3,2,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1016,B1016)","v":"nomegestrol acetate"},"nomegestrol acetate","C038501",3,0,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1017,B1017)","v":"nonachlor"},"nonachlor","C001870",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1018,B1018)","v":"norethindrone enanthate"},"norethindrone enanthate","C024319",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1019,B1019)","v":"Noxythiolin"},"Noxythiolin","D009677",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1020,B1020)","v":"NSC 74859"},"NSC 74859","C520337",3,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1021,B1021)","v":"N-succinimidyl 3-iodobenzoate"},"N-succinimidyl 3-iodobenzoate","C062337",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1022,B1022)","v":"Nystatin"},"Nystatin","D009761",3,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1023,B1023)","v":"o-Chlorobenzylidenemalonitrile"},"o-Chlorobenzylidenemalonitrile","D009763",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1024,B1024)","v":"omadacycline"},"omadacycline","C000591640",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1025,B1025)","v":"oxophenylarsine"},"oxophenylarsine","C029341",3,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1026,B1026)","v":"oxychlordane"},"oxychlordane","C008743",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1027,B1027)","v":"Oxythiamine"},"Oxythiamine","D010119",3,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1028,B1028)","v":"oxythiamine amyl disulfide"},"oxythiamine amyl disulfide","C061978",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1029,B1029)","v":"oxythiamine hexyl disulfide"},"oxythiamine hexyl disulfide","C061979",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1030,B1030)","v":"palmitoyl glycerol"},"palmitoyl glycerol","C027735",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1031,B1031)","v":"Patulin"},"Patulin","D010365",3,0,2,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1032,B1032)","v":"PD 135158"},"PD 135158","C065600",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1033,B1033)","v":"pectin"},"pectin","C030121",3,0,3,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1034,B1034)","v":"pentachloroanisole"},"pentachloroanisole","C015421",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1035,B1035)","v":"pentachlorobenzene"},"pentachlorobenzene","C003060",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1036,B1036)","v":"pentyl ether"},"pentyl ether","C488839",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1037,B1037)","v":"perflexane"},"perflexane","C078626",3,1,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1038,B1038)","v":"perfluorobutyric acid"},"perfluorobutyric acid","C033094",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1039,B1039)","v":"perfluoro-n-butyl iodide"},"perfluoro-n-butyl iodide","C496196",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1040,B1040)","v":"perfluorosulfonic acid"},"perfluorosulfonic acid","C040402",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1041,B1041)","v":"Phenol"},"Phenol","D019800",3,0,2,17,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1042,B1042)","v":"phenylisothiocyanate"},"phenylisothiocyanate","C005441",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1043,B1043)","v":"Phenylmercuric Acetate"},"Phenylmercuric Acetate","D010662",3,0,0,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1044,B1044)","v":"phenylmercuric nitrate, basic"},"phenylmercuric nitrate, basic","C008860",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1045,B1045)","v":"phorbol"},"phorbol","C033085",3,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1046,B1046)","v":"phosphatidylbutanol"},"phosphatidylbutanol","C068564",3,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1047,B1047)","v":"phosphatidylinositol 4-phosphate"},"phosphatidylinositol 4-phosphate","C037178",3,0,0,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1048,B1048)","v":"Phytic Acid"},"Phytic Acid","D010833",3,3,6,30,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1049,B1049)","v":"polychlorodibenzofuran"},"polychlorodibenzofuran","C016068",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1050,B1050)","v":"polysponin"},"polysponin","C018642",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1051,B1051)","v":"Polytetrafluoroethylene"},"Polytetrafluoroethylene","D011138",3,0,0,22,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1052,B1052)","v":"Potassium Chloride"},"Potassium Chloride","D011189",3,2,0,121,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1053,B1053)","v":"Procainamide"},"Procainamide","D011342",3,0,4,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1054,B1054)","v":"prochloraz"},"prochloraz","C045362",3,0,2,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1055,B1055)","v":"progoitrin"},"progoitrin","C009048",3,9,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1056,B1056)","v":"Promazine"},"Promazine","D011395",3,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1057,B1057)","v":"Prometryne"},"Prometryne","D011400",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1058,B1058)","v":"pronamide"},"pronamide","C001059",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1059,B1059)","v":"prorenoate potassium"},"prorenoate potassium","C010768",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1060,B1060)","v":"prostaglandin F1"},"prostaglandin F1","C100006",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1061,B1061)","v":"Putrescine"},"Putrescine","D011700",3,0,4,54,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1062,B1062)","v":"pyrazole"},"pyrazole","C031280",3,2,2,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1063,B1063)","v":"pyrene"},"pyrene","C030984",3,1,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1064,B1064)","v":"R 59022"},"R 59022","C047505",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1065,B1065)","v":"Rifabutin"},"Rifabutin","D017828",3,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1066,B1066)","v":"Ritodrine"},"Ritodrine","D012312",3,2,8,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1067,B1067)","v":"rocuronium"},"rocuronium","C061870",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1068,B1068)","v":"RPI-1 compound"},"RPI-1 compound","C477359",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1069,B1069)","v":"Rubella Vaccine"},"Rubella Vaccine","D012411",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1070,B1070)","v":"SC 37211"},"SC 37211","C046574",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1071,B1071)","v":"sesamodil"},"sesamodil","C064356",3,0,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1072,B1072)","v":"Sodium Acetate"},"Sodium Acetate","D019346",3,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1073,B1073)","v":"sodium bromate"},"sodium bromate","C060553",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1074,B1074)","v":"Sodium Dodecyl Sulfate"},"Sodium Dodecyl Sulfate","D012967",3,0,4,17,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1075,B1075)","v":"sodium metasilicate"},"sodium metasilicate","C025349",3,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1076,B1076)","v":"Sodium Salicylate"},"Sodium Salicylate","D012980",3,1,16,35,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1077,B1077)","v":"spinosad"},"spinosad","C415329",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1078,B1078)","v":"SRS-A"},"SRS-A","D013189",3,1,2,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1079,B1079)","v":"Stanozolol"},"Stanozolol","D013197",3,3,2,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1080,B1080)","v":"sulfadiazine, trimethoprim drug combination"},"sulfadiazine, trimethoprim drug combination","C024873",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1081,B1081)","v":"sulfamoxole, trimethoprim drug combination"},"sulfamoxole, trimethoprim drug combination","C013268",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1082,B1082)","v":"Sulfasalazine"},"Sulfasalazine","D012460",3,0,0,19,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1083,B1083)","v":"Sulindac"},"Sulindac","D013467",3,0,0,32,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1084,B1084)","v":"sulisobenzone"},"sulisobenzone","C009361",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1085,B1085)","v":"Suramin"},"Suramin","D013498",3,0,0,43,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1086,B1086)","v":"systhane"},"systhane","C446685",3,1,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1087,B1087)","v":"taurolidine"},"taurolidine","C012566",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1088,B1088)","v":"tebuconazole"},"tebuconazole","C087114",3,0,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1089,B1089)","v":"technetium Tc 99m (Sn)methylenediphosphonate"},"technetium Tc 99m (Sn)methylenediphosphonate","C023568",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1090,B1090)","v":"Terazosin"},"Terazosin","C041226",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1091,B1091)","v":"terbutryne"},"terbutryne","C010347",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1092,B1092)","v":"tert-Butyl Alcohol"},"tert-Butyl Alcohol","D020002",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1093,B1093)","v":"Tetanus Toxoid"},"Tetanus Toxoid","D013745",3,0,2,17,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1094,B1094)","v":"tetrahydropalmatine"},"tetrahydropalmatine","C014215",3,2,0,23,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1095,B1095)","v":"thiacloprid"},"thiacloprid","C417209",3,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1096,B1096)","v":"thiazopyr"},"thiazopyr","C091707",3,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1097,B1097)","v":"thiocarlide"},"thiocarlide","C100189",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1098,B1098)","v":"Thorium Dioxide"},"Thorium Dioxide","D013911",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1099,B1099)","v":"Thymine"},"Thymine","D013941",3,0,0,15,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1100,B1100)","v":"timoprazole"},"timoprazole","C038402",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1101,B1101)","v":"Trenbolone Acetate"},"Trenbolone Acetate","D014204",3,0,4,35,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1102,B1102)","v":"trichlorobenzene"},"trichlorobenzene","C036720",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1103,B1103)","v":"trifluoroiodomethane"},"trifluoroiodomethane","C105057",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1104,B1104)","v":"Trifluralin"},"Trifluralin","D014274",3,0,2,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1105,B1105)","v":"trimethylamine"},"trimethylamine","C023336",3,2,4,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1106,B1106)","v":"Triolein"},"Triolein","D014304",3,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1107,B1107)","v":"Triparanol"},"Triparanol","D014308",3,3,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1108,B1108)","v":"triphenyl phosphate"},"triphenyl phosphate","C005445",3,2,2,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1109,B1109)","v":"tris(2-butoxyethyl) phosphate"},"tris(2-butoxyethyl) phosphate","C013320",3,1,4,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1110,B1110)","v":"trisialoganglioside GT1"},"trisialoganglioside GT1","C016481",3,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1111,B1111)","v":"Tropolone"},"Tropolone","D014334",3,0,0,18,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1112,B1112)","v":"tungstic(VI) acid"},"tungstic(VI) acid","C021101",3,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1113,B1113)","v":"turmeric extract"},"turmeric extract","C012596",3,2,2,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1114,B1114)","v":"UK 453,061"},"UK 453,061","C531151",3,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1115,B1115)","v":"Uranyl Nitrate"},"Uranyl Nitrate","D014502",3,0,0,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1116,B1116)","v":"Veratridine"},"Veratridine","D014701",3,0,0,76,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1117,B1117)","v":"Veratrine"},"Veratrine","D014702",3,0,0,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1118,B1118)","v":"vesnarinone"},"vesnarinone","C041667",3,1,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1119,B1119)","v":"vinclozolin"},"vinclozolin","C025643",3,3,2,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1120,B1120)","v":"yingliu"},"yingliu","C000614898",3,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1121,B1121)","v":"Ziram"},"Ziram","D015039",3,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1122,B1122)","v":"zosterin"},"zosterin","C070927",3,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1123,B1123)","v":"Methotrexate"},"Methotrexate","D008727",2,0,10,146,76]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1124,B1124)","v":"Paroxetine"},"Paroxetine","D017374",2,5,6,156,28]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1125,B1125)","v":"coenzyme Q10"},"coenzyme Q10","C024989",2,8,6,101,21]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1126,B1126)","v":"Dexmedetomidine"},"Dexmedetomidine","D020927",2,0,0,148,20]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1127,B1127)","v":"Dihydroergotoxine"},"Dihydroergotoxine","D004088",2,2,2,36,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1128,B1128)","v":"Paclitaxel"},"Paclitaxel","D017239",2,2,2,124,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1129,B1129)","v":"Rolipram"},"Rolipram","D020889",2,0,0,125,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1130,B1130)","v":"Piribedil"},"Piribedil","D010891",2,0,2,18,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1131,B1131)","v":"Betaine"},"Betaine","D001622",2,3,4,63,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1132,B1132)","v":"Lutein"},"Lutein","D014975",2,0,0,25,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1133,B1133)","v":"Methoxyhydroxyphenylglycol"},"Methoxyhydroxyphenylglycol","D008734",2,1,6,128,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1134,B1134)","v":"fucoidan"},"fucoidan","C007789",2,0,0,46,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1135,B1135)","v":"4-phenylbutyric acid"},"4-phenylbutyric acid","C075773",2,2,0,27,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1136,B1136)","v":"Meperidine"},"Meperidine","D008614",2,1,2,12,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1137,B1137)","v":"Smoke"},"Smoke","D012906",2,2,2,216,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1138,B1138)","v":"kaempferol"},"kaempferol","C006552",2,2,0,65,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1139,B1139)","v":"Selenic Acid"},"Selenic Acid","D064586",2,2,2,9,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1140,B1140)","v":"Sugammadex"},"Sugammadex","C453980",2,0,0,2,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1141,B1141)","v":"anatabine"},"anatabine","C012737",2,2,0,2,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1142,B1142)","v":"artemisinine"},"artemisinine","C031327",2,2,0,23,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1143,B1143)","v":"Ciprofloxacin"},"Ciprofloxacin","D002939",2,1,6,22,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1144,B1144)","v":"Ferrosoferric Oxide"},"Ferrosoferric Oxide","D052203",2,2,0,7,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1145,B1145)","v":"methyl iodide"},"methyl iodide","C014055",2,2,0,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1146,B1146)","v":"Prostaglandin D2"},"Prostaglandin D2","D015230",2,0,0,208,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1147,B1147)","v":"ropivacaine"},"ropivacaine","C037663",2,0,0,19,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1148,B1148)","v":"Sorbitol"},"Sorbitol","D013012",2,3,6,12,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1149,B1149)","v":"Tranylcypromine"},"Tranylcypromine","D014191",2,2,6,21,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1150,B1150)","v":"Ashwagandha"},"Ashwagandha","C030693",2,4,0,10,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1151,B1151)","v":"Bendroflumethiazide"},"Bendroflumethiazide","D001539",2,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1152,B1152)","v":"Hydroxocobalamin"},"Hydroxocobalamin","D006879",2,2,0,2,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1153,B1153)","v":"Succinic Acid"},"Succinic Acid","D019802",2,0,8,14,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1154,B1154)","v":"Sulfur Hexafluoride"},"Sulfur Hexafluoride","D013459",2,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1155,B1155)","v":"Taurochenodeoxycholic Acid"},"Taurochenodeoxycholic Acid","D013655",2,2,0,31,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1156,B1156)","v":"tauroursodeoxycholic acid"},"tauroursodeoxycholic acid","C031655",2,2,0,28,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1157,B1157)","v":"ubiquinone 9"},"ubiquinone 9","C030571",2,4,4,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1158,B1158)","v":"15-deoxy-delta(12,14)-prostaglandin J2"},"15-deoxy-delta(12,14)-prostaglandin J2","C097240",2,0,0,83,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1159,B1159)","v":"2-tolidine"},"2-tolidine","C009501",2,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1160,B1160)","v":"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"},"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate","C097869",2,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1161,B1161)","v":"3-(2-mercaptoethyl)quinazoline-2,4(1H,3H)-dione"},"3-(2-mercaptoethyl)quinazoline-2,4(1H,3H)-dione","C086987",2,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1162,B1162)","v":"3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene"},"3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene","C497936",2,2,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1163,B1163)","v":"3,4,5,3',4',5'-hexachlorobiphenyl"},"3,4,5,3',4',5'-hexachlorobiphenyl","C027309",2,2,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1164,B1164)","v":"6-methoxybenzoxazolinone"},"6-methoxybenzoxazolinone","C031896",2,3,2,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1165,B1165)","v":"Agar"},"Agar","D000362",2,0,6,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1166,B1166)","v":"ahnjeonbaekho-tang"},"ahnjeonbaekho-tang","C528667",2,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1167,B1167)","v":"alpha-glycerophosphoric acid"},"alpha-glycerophosphoric acid","C029620",2,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1168,B1168)","v":"Aminopterin"},"Aminopterin","D000630",2,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1169,B1169)","v":"Ammonium Chloride"},"Ammonium Chloride","D000643",2,0,0,35,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1170,B1170)","v":"Ammonium Sulfate"},"Ammonium Sulfate","D000645",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1171,B1171)","v":"Arabinose"},"Arabinose","D001089",2,0,0,21,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1172,B1172)","v":"ascaridole"},"ascaridole","C043372",2,2,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1173,B1173)","v":"Atracurium"},"Atracurium","D001279",2,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1174,B1174)","v":"Aurothioglucose"},"Aurothioglucose","D006051",2,4,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1175,B1175)","v":"Bentonite"},"Bentonite","D001546",2,3,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1176,B1176)","v":"benz(a)anthracene"},"benz(a)anthracene","C030935",2,1,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1177,B1177)","v":"benzofuran"},"benzofuran","C105430",2,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1178,B1178)","v":"Biotin"},"Biotin","D001710",2,7,16,124,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1179,B1179)","v":"Brefeldin A"},"Brefeldin A","D020126",2,0,0,22,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1180,B1180)","v":"Busulfan"},"Busulfan","D002066",2,1,0,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1181,B1181)","v":"butylparaben"},"butylparaben","C038091",2,2,2,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1182,B1182)","v":"captax"},"captax","C005563",2,4,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1183,B1183)","v":"CD1a antigen"},"CD1a antigen","C419393",2,2,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1184,B1184)","v":"CD3 Complex"},"CD3 Complex","D017252",2,1,0,166,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1185,B1185)","v":"CGP 12177"},"CGP 12177","C033394",2,2,2,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1186,B1186)","v":"Chlormerodrin"},"Chlormerodrin","D002717",2,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1187,B1187)","v":"cholesteryl iopanoate"},"cholesteryl iopanoate","C039133",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1188,B1188)","v":"contrast agent BR1"},"contrast agent BR1","C420843",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1189,B1189)","v":"dibenzazepine"},"dibenzazepine","C527817",2,2,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1190,B1190)","v":"Dihydroergotamine"},"Dihydroergotamine","D004087",2,0,4,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1191,B1191)","v":"disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"},"disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate","C076126",2,2,0,16,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1192,B1192)","v":"dithiol"},"dithiol","C004848",2,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1193,B1193)","v":"Dry Ice"},"Dry Ice","D004367",2,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1194,B1194)","v":"EBV-encoded nuclear antigen 1"},"EBV-encoded nuclear antigen 1","C417029",2,2,0,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1195,B1195)","v":"Ergonovine"},"Ergonovine","D004874",2,0,6,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1196,B1196)","v":"etonitazene"},"etonitazene","C084835",2,3,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1197,B1197)","v":"gamma-cyclodextrin"},"gamma-cyclodextrin","C023792",2,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1198,B1198)","v":"genapol X 080"},"genapol X 080","C116996",2,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1199,B1199)","v":"Guaiacol"},"Guaiacol","D006139",2,2,0,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1200,B1200)","v":"Guanethidine"},"Guanethidine","D006145",2,14,12,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1201,B1201)","v":"Hexestrol"},"Hexestrol","D006589",2,1,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1202,B1202)","v":"Hydroxyindoleacetic Acid"},"Hydroxyindoleacetic Acid","D006897",2,3,12,118,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1203,B1203)","v":"hydroxysuccinimidyl-4-azidobenzoate"},"hydroxysuccinimidyl-4-azidobenzoate","C029534",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1204,B1204)","v":"iodoantipyrine"},"iodoantipyrine","C008135",2,0,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1205,B1205)","v":"ivacaftor"},"ivacaftor","C545203",2,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1206,B1206)","v":"Lysergic Acid"},"Lysergic Acid","D008237",2,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1207,B1207)","v":"lysophosphatidylinositol"},"lysophosphatidylinositol","C025449",2,0,0,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1208,B1208)","v":"mannose-6-phosphate"},"mannose-6-phosphate","C027693",2,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1209,B1209)","v":"Mechlorethamine"},"Mechlorethamine","D008466",2,0,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1210,B1210)","v":"methyl triclosan"},"methyl triclosan","C502486",2,3,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1211,B1211)","v":"methyl-beta-cyclodextrin"},"methyl-beta-cyclodextrin","C108732",2,0,0,29,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1212,B1212)","v":"mustard oil"},"mustard oil","C027793",2,6,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1213,B1213)","v":"N-acetyllactosamine"},"N-acetyllactosamine","C000458",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1214,B1214)","v":"Nafenopin"},"Nafenopin","D009255",2,2,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1215,B1215)","v":"Neomycin"},"Neomycin","D009355",2,2,6,32,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1216,B1216)","v":"Neutral Red"},"Neutral Red","D009499",2,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1217,B1217)","v":"N-glycolylneuraminic acid"},"N-glycolylneuraminic acid","C032592",2,2,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1218,B1218)","v":"nitrosobis(2-oxopropyl)amine"},"nitrosobis(2-oxopropyl)amine","C013622",2,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1219,B1219)","v":"nomilin"},"nomilin","C059405",2,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1220,B1220)","v":"obacunone"},"obacunone","C067207",2,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1221,B1221)","v":"octylmethoxycinnamate"},"octylmethoxycinnamate","C118580",2,2,6,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1222,B1222)","v":"O-deacetyl platelet activating factor"},"O-deacetyl platelet activating factor","C029271",2,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1223,B1223)","v":"Oxalic Acid"},"Oxalic Acid","D019815",2,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1224,B1224)","v":"perfluorohexanoic acid"},"perfluorohexanoic acid","C479228",2,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1225,B1225)","v":"Periodic Acid"},"Periodic Acid","D010504",2,2,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1226,B1226)","v":"Pertussis Vaccine"},"Pertussis Vaccine","D010567",2,0,0,11,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1227,B1227)","v":"phenethylamine"},"phenethylamine","C029261",2,0,0,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1228,B1228)","v":"Phenolsulfonphthalein"},"Phenolsulfonphthalein","D010637",2,0,2,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1229,B1229)","v":"phenthoate"},"phenthoate","C008838",2,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1230,B1230)","v":"Propyliodone"},"Propyliodone","D011440",2,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1231,B1231)","v":"ronnel"},"ronnel","C091929",2,2,8,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1232,B1232)","v":"Selenious Acid"},"Selenious Acid","D020887",2,0,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1233,B1233)","v":"sephadex"},"sephadex","C025614",2,2,8,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1234,B1234)","v":"serum thyroid hormone reducing factor"},"serum thyroid hormone reducing factor","C067683",2,3,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1235,B1235)","v":"Silver Nitrate"},"Silver Nitrate","D012835",2,2,4,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1236,B1236)","v":"simmondsin"},"simmondsin","C089377",2,3,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1237,B1237)","v":"sodium thiosulfate"},"sodium thiosulfate","C017717",2,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1238,B1238)","v":"sulfathiazole"},"sulfathiazole","C005312",2,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1239,B1239)","v":"Technegas"},"Technegas","C056708",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1240,B1240)","v":"Technetium Tc 99m ciprofloxacin"},"Technetium Tc 99m ciprofloxacin","C431804",2,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1241,B1241)","v":"Thiamine Pyrophosphate"},"Thiamine Pyrophosphate","D013835",2,1,4,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1242,B1242)","v":"Thioacetamide"},"Thioacetamide","D013853",2,0,2,37,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1243,B1243)","v":"Tolazoline"},"Tolazoline","D014043",2,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1244,B1244)","v":"Tuberculin"},"Tuberculin","D014373",2,0,6,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1245,B1245)","v":"Tubocurarine"},"Tubocurarine","D014403",2,1,8,38,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1246,B1246)","v":"Turpentine"},"Turpentine","D014425",2,1,6,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1247,B1247)","v":"Vitamin K 3"},"Vitamin K 3","D024483",2,2,0,18,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1248,B1248)","v":"Fructose"},"Fructose","D005632",1,4,20,426,151]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1249,B1249)","v":"sevoflurane"},"sevoflurane","C009250",1,0,0,436,117]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1250,B1250)","v":"Amantadine"},"Amantadine","D000547",1,0,0,68,44]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1251,B1251)","v":"Particulate Matter"},"Particulate Matter","D052638",1,1,0,221,33]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1252,B1252)","v":"Nimodipine"},"Nimodipine","D009553",1,1,2,207,32]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1253,B1253)","v":"remifentanil"},"remifentanil","C071741",1,0,0,37,30]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1254,B1254)","v":"Medroxyprogesterone Acetate"},"Medroxyprogesterone Acetate","D017258",1,0,2,78,28]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1255,B1255)","v":"Atorvastatin Calcium"},"Atorvastatin Calcium","D000069059",1,1,0,241,27]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1256,B1256)","v":"Buprenorphine"},"Buprenorphine","D002047",1,1,0,13,26]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1257,B1257)","v":"Eicosapentaenoic Acid"},"Eicosapentaenoic Acid","D015118",1,1,2,201,25]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1258,B1258)","v":"Nortriptyline"},"Nortriptyline","D009661",1,1,4,22,22]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1259,B1259)","v":"Diphenhydramine"},"Diphenhydramine","D004155",1,3,0,4,21]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1260,B1260)","v":"Kainic Acid"},"Kainic Acid","D007608",1,0,10,3984,21]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1261,B1261)","v":"Apomorphine"},"Apomorphine","D001058",1,3,0,156,20]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1262,B1262)","v":"aluminum chloride"},"aluminum chloride","C010845",1,0,0,206,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1263,B1263)","v":"Succimer"},"Succimer","D004113",1,0,0,9,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1264,B1264)","v":"Carbidopa"},"Carbidopa","D002230",1,0,4,6,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1265,B1265)","v":"efavirenz"},"efavirenz","C098320",1,0,0,22,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1266,B1266)","v":"Flunitrazepam"},"Flunitrazepam","D005445",1,2,6,84,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1267,B1267)","v":"Ondansetron"},"Ondansetron","D017294",1,0,0,30,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1268,B1268)","v":"Celecoxib"},"Celecoxib","D000068579",1,0,0,75,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1269,B1269)","v":"Oxycodone"},"Oxycodone","D010098",1,0,4,20,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1270,B1270)","v":"Pravastatin"},"Pravastatin","D017035",1,0,0,53,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1271,B1271)","v":"rofecoxib"},"rofecoxib","C116926",1,0,0,29,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1272,B1272)","v":"Ephedrine"},"Ephedrine","D004809",1,3,18,20,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1273,B1273)","v":"Dextropropoxyphene"},"Dextropropoxyphene","D011431",1,0,2,0,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1274,B1274)","v":"Procyclidine"},"Procyclidine","D011352",1,0,0,4,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1275,B1275)","v":"Trichloroethylene"},"Trichloroethylene","D014241",1,0,0,60,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1276,B1276)","v":"3-(2,2,2-trimethylhydrazine)propionate"},"3-(2,2,2-trimethylhydrazine)propionate","C050147",1,2,2,10,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1277,B1277)","v":"Calcium Carbonate"},"Calcium Carbonate","D002119",1,0,20,15,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1278,B1278)","v":"Cyproterone Acetate"},"Cyproterone Acetate","D017373",1,0,4,10,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1279,B1279)","v":"Pemoline"},"Pemoline","D010389",1,0,0,2,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1280,B1280)","v":"Psilocybin"},"Psilocybin","D011562",1,2,0,18,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1281,B1281)","v":"Pyruvic Acid"},"Pyruvic Acid","D019289",1,1,4,121,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1282,B1282)","v":"Quinidine"},"Quinidine","D011802",1,3,4,9,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1283,B1283)","v":"tibolone"},"tibolone","C027385",1,0,2,34,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1284,B1284)","v":"3-Hydroxybutyric Acid"},"3-Hydroxybutyric Acid","D020155",1,2,2,45,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1285,B1285)","v":"cevimeline"},"cevimeline","C059240",1,0,0,27,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1286,B1286)","v":"Doxepin"},"Doxepin","D004316",1,0,0,1,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1287,B1287)","v":"montelukast"},"montelukast","C093875",1,0,0,30,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1288,B1288)","v":"nobiletin"},"nobiletin","C008661",1,0,0,56,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1289,B1289)","v":"parecoxib"},"parecoxib","C409945",1,0,0,13,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1290,B1290)","v":"tropisetron"},"tropisetron","C045504",1,0,0,16,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1291,B1291)","v":"(+)-JQ1 compound"},"(+)-JQ1 compound","C561695",1,0,0,22,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1292,B1292)","v":"Carmustine"},"Carmustine","D002330",1,0,0,7,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1293,B1293)","v":"Fingolimod Hydrochloride"},"Fingolimod Hydrochloride","D000068876",1,0,0,122,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1294,B1294)","v":"Glycopyrrolate"},"Glycopyrrolate","D006024",1,0,0,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1295,B1295)","v":"Sufentanil"},"Sufentanil","D017409",1,0,0,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1296,B1296)","v":"Yohimbine"},"Yohimbine","D015016",1,1,2,78,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1297,B1297)","v":"2,4,5-Trichlorophenoxyacetic Acid"},"2,4,5-Trichlorophenoxyacetic Acid","D015085",1,0,0,3,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1298,B1298)","v":"Acetone"},"Acetone","D000096",1,1,2,1,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1299,B1299)","v":"Ajmaline"},"Ajmaline","D000404",1,0,0,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1300,B1300)","v":"Benzoic Acid"},"Benzoic Acid","D019817",1,0,2,4,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1301,B1301)","v":"Biopterin"},"Biopterin","D001708",1,7,6,70,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1302,B1302)","v":"Butter"},"Butter","D002079",1,0,2,3,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1303,B1303)","v":"Butyric Acid"},"Butyric Acid","D020148",1,0,0,253,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1304,B1304)","v":"Chloral Hydrate"},"Chloral Hydrate","D002697",1,2,2,12,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1305,B1305)","v":"Dantrolene"},"Dantrolene","D003620",1,1,4,69,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1306,B1306)","v":"Dichlorvos"},"Dichlorvos","D004006",1,1,2,30,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1307,B1307)","v":"Diphtheria Toxoid"},"Diphtheria Toxoid","D004168",1,0,0,1,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1308,B1308)","v":"Fructosamine"},"Fructosamine","D019270",1,5,10,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1309,B1309)","v":"Heparin, Low-Molecular-Weight"},"Heparin, Low-Molecular-Weight","D006495",1,1,5,30,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1310,B1310)","v":"Leucovorin"},"Leucovorin","D002955",1,0,0,5,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1311,B1311)","v":"Meclofenoxate"},"Meclofenoxate","D002504",1,0,2,26,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1312,B1312)","v":"Palmitic Acid"},"Palmitic Acid","D019308",1,0,8,150,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1313,B1313)","v":"Peroxynitrous Acid"},"Peroxynitrous Acid","D030421",1,3,0,57,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1314,B1314)","v":"Phenformin"},"Phenformin","D010629",1,0,2,4,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1315,B1315)","v":"Propane"},"Propane","D011407",1,0,2,15,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1316,B1316)","v":"Tetrodotoxin"},"Tetrodotoxin","D013779",1,0,0,195,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1317,B1317)","v":"Thiotepa"},"Thiotepa","D013852",1,2,0,8,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1318,B1318)","v":"Triprolidine"},"Triprolidine","D014311",1,0,0,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1319,B1319)","v":"1,4-dihydropyridine"},"1,4-dihydropyridine","C038806",1,1,0,44,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1320,B1320)","v":"2,4-dithiobiuret"},"2,4-dithiobiuret","C007540",1,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1321,B1321)","v":"3,4-Dihydroxyphenylacetic Acid"},"3,4-Dihydroxyphenylacetic Acid","D015102",1,0,2,42,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1322,B1322)","v":"Albuterol"},"Albuterol","D000420",1,1,6,26,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1323,B1323)","v":"alpha-hydroxyglutarate"},"alpha-hydroxyglutarate","C019417",1,0,0,2,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1324,B1324)","v":"benzotriazole"},"benzotriazole","C012771",1,1,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1325,B1325)","v":"cabergoline"},"cabergoline","C047047",1,2,8,14,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1326,B1326)","v":"Congo Red"},"Congo Red","D003224",1,0,0,15,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1327,B1327)","v":"Fluconazole"},"Fluconazole","D015725",1,0,0,7,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1328,B1328)","v":"Homovanillic Acid"},"Homovanillic Acid","D006719",1,0,0,20,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1329,B1329)","v":"Materia Medica"},"Materia Medica","D008419",1,0,12,16,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1330,B1330)","v":"Muscarine"},"Muscarine","D009116",1,0,0,54,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1331,B1331)","v":"Normetanephrine"},"Normetanephrine","D009647",1,0,0,4,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1332,B1332)","v":"Soybean Oil"},"Soybean Oil","D013024",1,0,0,26,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1333,B1333)","v":"(4-(4'-chloro-2'-fluoro)phenylamino)-6,7-dimethylquinazoline"},"(4-(4'-chloro-2'-fluoro)phenylamino)-6,7-dimethylquinazoline","C575425",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1334,B1334)","v":"1,1,2-trichloropropane"},"1,1,2-trichloropropane","C047725",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1335,B1335)","v":"1,1-cyclopropanediol"},"1,1-cyclopropanediol","C018885",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1336,B1336)","v":"1,2,3-trichloropropane"},"1,2,3-trichloropropane","C009536",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1337,B1337)","v":"1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane"},"1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane","C517232",1,0,5,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1338,B1338)","v":"1,2-distearoyllecithin"},"1,2-distearoyllecithin","C010942",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1339,B1339)","v":"1,3-propanediol"},"1,3-propanediol","C041787",1,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1340,B1340)","v":"11-hydroxy-5,8,12,14-eicosatetraenoic acid"},"11-hydroxy-5,8,12,14-eicosatetraenoic acid","C027356",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1341,B1341)","v":"15-(4-iodophenyl)-3,3-dimethylpentadecanoic acid"},"15-(4-iodophenyl)-3,3-dimethylpentadecanoic acid","C049337",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1342,B1342)","v":"19-Iodocholesterol"},"19-Iodocholesterol","D015071",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1343,B1343)","v":"1-anilino-8-naphthalenesulfonate"},"1-anilino-8-naphthalenesulfonate","C027132",1,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1344,B1344)","v":"2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one"},"2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one","C085911",1,0,0,15,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1345,B1345)","v":"2,2',3,3',4,4',6,6'-octabromodiphenyl ether"},"2,2',3,3',4,4',6,6'-octabromodiphenyl ether","C511855",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1346,B1346)","v":"2,2',4,4',5-pentachlorobiphenyl"},"2,2',4,4',5-pentachlorobiphenyl","C500336",1,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1347,B1347)","v":"2,3,6-trichlorotoluene"},"2,3,6-trichlorotoluene","C039047",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1348,B1348)","v":"2,4-Dinitrophenol"},"2,4-Dinitrophenol","D019297",1,5,14,15,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1349,B1349)","v":"2,8-dihydromirex"},"2,8-dihydromirex","C023613",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1350,B1350)","v":"2-cresol"},"2-cresol","C034047",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1351,B1351)","v":"2-isobutyl-3-methoxypyrazine"},"2-isobutyl-3-methoxypyrazine","C034376",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1352,B1352)","v":"2-mercaptoacetate"},"2-mercaptoacetate","C017487",1,2,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1353,B1353)","v":"2-mercaptoimidazole"},"2-mercaptoimidazole","C077232",1,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1354,B1354)","v":"2-mercaptopyrazine"},"2-mercaptopyrazine","C402065",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1355,B1355)","v":"2-Naphthylamine"},"2-Naphthylamine","D015081",1,0,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1356,B1356)","v":"3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone"},"3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone","C482900",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1357,B1357)","v":"3,3'-diindolylmethane"},"3,3'-diindolylmethane","C016392",1,0,0,32,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1358,B1358)","v":"3,3'-dioctadecylindocarbocyanine"},"3,3'-dioctadecylindocarbocyanine","C024286",1,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1359,B1359)","v":"3,4-dihydroxypyridine"},"3,4-dihydroxypyridine","C007435",1,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1360,B1360)","v":"3,5,6-trichloro-2-pyridinol"},"3,5,6-trichloro-2-pyridinol","C012587",1,1,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1361,B1361)","v":"32-O-(1-hydroxyethylindol-5-yl)ascomycin"},"32-O-(1-hydroxyethylindol-5-yl)ascomycin","C110188",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1362,B1362)","v":"3-amino-1-methyl-5H-pyrido(4,3-b)indole"},"3-amino-1-methyl-5H-pyrido(4,3-b)indole","C019133",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1363,B1363)","v":"3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl"},"3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl","C499782",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1364,B1364)","v":"3-cyclobutene-1,2-dione"},"3-cyclobutene-1,2-dione","C110624",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1365,B1365)","v":"3-iodobenzoic acid"},"3-iodobenzoic acid","C038262",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1366,B1366)","v":"3-O-methylfluorescein phosphate"},"3-O-methylfluorescein phosphate","C032079",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1367,B1367)","v":"3-phenoxybenzoic acid"},"3-phenoxybenzoic acid","C017618",1,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1368,B1368)","v":"4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid"},"4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid","C038864",1,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1369,B1369)","v":"4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbene"},"4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbene","C527756",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1370,B1370)","v":"4,4'-thiodianiline"},"4,4'-thiodianiline","C011749",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1371,B1371)","v":"4-cresol"},"4-cresol","C032538",1,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1372,B1372)","v":"4-hydroxyphenylpyruvic acid"},"4-hydroxyphenylpyruvic acid","C010590",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1373,B1373)","v":"4-thiouracil"},"4-thiouracil","C114719",1,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1374,B1374)","v":"5-iodo-4-hydroxy-7,10,13,16,19-docosapentaenoic acid gamma-lactone"},"5-iodo-4-hydroxy-7,10,13,16,19-docosapentaenoic acid gamma-lactone","C031204",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1375,B1375)","v":"5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione"},"5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione","C067418",1,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1376,B1376)","v":"6-Aminonicotinamide"},"6-Aminonicotinamide","D015120",1,1,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1377,B1377)","v":"6-phosphogluconic acid"},"6-phosphogluconic acid","C008884",1,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1378,B1378)","v":"7-(O)-carboxymethyl daidzein N-t-Boc-hexylenediamine conjugate"},"7-(O)-carboxymethyl daidzein N-t-Boc-hexylenediamine conjugate","C576978",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1379,B1379)","v":"8-mercaptoquinoline"},"8-mercaptoquinoline","C087618",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1380,B1380)","v":"acetonitrile"},"acetonitrile","C032159",1,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1381,B1381)","v":"Acetylgalactosamine"},"Acetylgalactosamine","D000116",1,0,0,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1382,B1382)","v":"Adosterol"},"Adosterol","D000301",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1383,B1383)","v":"adrenal microsomal antigen"},"adrenal microsomal antigen","C055727",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1384,B1384)","v":"adroxazine"},"adroxazine","C045437",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1385,B1385)","v":"Akt-I-1,2 compound"},"Akt-I-1,2 compound","C501521",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1386,B1386)","v":"alginic acid"},"alginic acid","C008970",1,0,0,61,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1387,B1387)","v":"allocryptopine"},"allocryptopine","C109505",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1388,B1388)","v":"allyl isothiocyanate"},"allyl isothiocyanate","C004471",1,5,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1389,B1389)","v":"Allylamine"},"Allylamine","D000499",1,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1390,B1390)","v":"alpha,2,6-trichlorotoluene"},"alpha,2,6-trichlorotoluene","C041916",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1391,B1391)","v":"alpha-naphthyl thiourea"},"alpha-naphthyl thiourea","C005277",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1392,B1392)","v":"aluminoborate cement"},"aluminoborate cement","C036916",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1393,B1393)","v":"amberlite"},"amberlite","C046797",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1394,B1394)","v":"Amifostine"},"Amifostine","D004999",1,0,0,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1395,B1395)","v":"Ampicillin"},"Ampicillin","D000667",1,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1396,B1396)","v":"Amylose"},"Amylose","D000688",1,0,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1397,B1397)","v":"Antimony Sodium Gluconate"},"Antimony Sodium Gluconate","D000967",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1398,B1398)","v":"aurotioprol"},"aurotioprol","C013394",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1399,B1399)","v":"Azaguanine"},"Azaguanine","D001375",1,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1400,B1400)","v":"Azure A"},"Azure A","C025818",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1401,B1401)","v":"Barium Sulfate"},"Barium Sulfate","D001466",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1402,B1402)","v":"benzalazine"},"benzalazine","C085292",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1403,B1403)","v":"benzotrichloride"},"benzotrichloride","C018847",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1404,B1404)","v":"bisphenol F"},"bisphenol F","C000611646",1,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1405,B1405)","v":"BN 50730"},"BN 50730","C066686",1,0,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1406,B1406)","v":"Bolton-Hunter reagent"},"Bolton-Hunter reagent","C022581",1,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1407,B1407)","v":"Bouin's solution"},"Bouin's solution","C026239",1,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1408,B1408)","v":"bromoacetate"},"bromoacetate","C016274",1,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1409,B1409)","v":"Brucella Vaccine"},"Brucella Vaccine","D002004",1,3,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1410,B1410)","v":"Budesonide"},"Budesonide","D019819",1,0,0,21,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1411,B1411)","v":"CA-19-9 Antigen"},"CA-19-9 Antigen","D018395",1,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1412,B1412)","v":"CA-50 antigen"},"CA-50 antigen","C082699",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1413,B1413)","v":"calcium acetate"},"calcium acetate","C120662",1,0,4,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1414,B1414)","v":"Calcium Citrate"},"Calcium Citrate","D019355",1,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1415,B1415)","v":"carbomycin"},"carbomycin","C059423",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1416,B1416)","v":"CD1b antigen"},"CD1b antigen","C419394",1,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1417,B1417)","v":"cellulose sulfate"},"cellulose sulfate","C020254",1,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1418,B1418)","v":"Chalcone"},"Chalcone","D002599",1,0,0,46,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1419,B1419)","v":"Chlorisondamine"},"Chlorisondamine","D002714",1,0,0,16,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1420,B1420)","v":"Chlormadinone Acetate"},"Chlormadinone Acetate","D002715",1,1,6,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1421,B1421)","v":"Chloroform"},"Chloroform","D002725",1,0,0,13,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1422,B1422)","v":"Chlorophyll"},"Chlorophyll","D002734",1,2,0,55,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1423,B1423)","v":"Chlorprothixene"},"Chlorprothixene","D002749",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1424,B1424)","v":"Cholestanol"},"Cholestanol","D004083",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1425,B1425)","v":"ciglitazone"},"ciglitazone","C039671",1,0,0,42,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1426,B1426)","v":"cisatracurium"},"cisatracurium","C101584",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1427,B1427)","v":"Clorgyline"},"Clorgyline","D003010",1,0,0,28,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1428,B1428)","v":"Colestipol"},"Colestipol","D003084",1,5,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1429,B1429)","v":"Collodion"},"Collodion","D003101",1,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1430,B1430)","v":"Conus magus toxin"},"Conus magus toxin","C053423",1,0,0,40,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1431,B1431)","v":"cresyl violet"},"cresyl violet","C028911",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1432,B1432)","v":"crystalloid solutions"},"crystalloid solutions","C007162",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1433,B1433)","v":"dansyl oligoganglioside G(M1)"},"dansyl oligoganglioside G(M1)","C030333",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1434,B1434)","v":"DEAE-Cellulose"},"DEAE-Cellulose","D003636",1,0,4,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1435,B1435)","v":"DEAE-Dextran"},"DEAE-Dextran","D003637",1,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1436,B1436)","v":"dehydroandrographolide"},"dehydroandrographolide","C478098",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1437,B1437)","v":"Dehydroascorbic Acid"},"Dehydroascorbic Acid","D003683",1,0,0,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1438,B1438)","v":"Dietary Fiber"},"Dietary Fiber","D004043",1,2,10,63,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1439,B1439)","v":"diethylthiourea"},"diethylthiourea","C035318",1,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1440,B1440)","v":"Diff Quik"},"Diff Quik","C067461",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1441,B1441)","v":"Digitonin"},"Digitonin","D004072",1,1,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1442,B1442)","v":"dihydro-DIDS"},"dihydro-DIDS","C018564",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1443,B1443)","v":"diolein"},"diolein","C013965",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1444,B1444)","v":"Dithionite"},"Dithionite","D004227",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1445,B1445)","v":"Ditiocarb"},"Ditiocarb","D004050",1,0,2,89,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1446,B1446)","v":"Dobutamine"},"Dobutamine","D004280",1,4,4,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1447,B1447)","v":"dolichol monophosphate"},"dolichol monophosphate","C028306",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1448,B1448)","v":"dolichol-D-glucosylmonophosphate"},"dolichol-D-glucosylmonophosphate","C002968",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1449,B1449)","v":"Dowex 50"},"Dowex 50","C077982",1,1,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1450,B1450)","v":"Durapatite"},"Durapatite","D017886",1,0,0,109,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1451,B1451)","v":"eicosapentaenoic acid ethyl ester"},"eicosapentaenoic acid ethyl ester","C035276",1,1,2,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1452,B1452)","v":"EMLA"},"EMLA","C036626",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1453,B1453)","v":"enterotoxin, Clostridium"},"enterotoxin, Clostridium","C035598",1,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1454,B1454)","v":"Eosine Yellowish-(YS)"},"Eosine Yellowish-(YS)","D004801",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1455,B1455)","v":"Ethamoxytriphetol"},"Ethamoxytriphetol","D004978",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1456,B1456)","v":"Ethylestrenol"},"Ethylestrenol","D005032",1,0,6,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1457,B1457)","v":"ethyl-p-hydroxybenzoate"},"ethyl-p-hydroxybenzoate","C012313",1,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1458,B1458)","v":"Ethynodiol Diacetate"},"Ethynodiol Diacetate","D005040",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1459,B1459)","v":"Farnesol"},"Farnesol","D005204",1,0,0,19,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1460,B1460)","v":"Fenbendazole"},"Fenbendazole","D005273",1,0,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1461,B1461)","v":"Flufenamic Acid"},"Flufenamic Acid","D005439",1,2,2,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1462,B1462)","v":"fluorosulfonic acid"},"fluorosulfonic acid","C046106",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1463,B1463)","v":"Fluspirilene"},"Fluspirilene","D005484",1,0,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1464,B1464)","v":"formic acid"},"formic acid","C030544",1,0,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1465,B1465)","v":"Forssman Antigen"},"Forssman Antigen","D005577",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1466,B1466)","v":"fumonisin B1"},"fumonisin B1","C056933",1,0,0,43,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1467,B1467)","v":"Gallopamil"},"Gallopamil","D005711",1,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1468,B1468)","v":"gam-du-tang"},"gam-du-tang","C494610",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1469,B1469)","v":"Gamguntang"},"Gamguntang","C511698",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1470,B1470)","v":"gamma-butyrobetaine"},"gamma-butyrobetaine","C002889",1,2,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1471,B1471)","v":"Gentian Violet"},"Gentian Violet","D005840",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1472,B1472)","v":"glaucine"},"glaucine","C005004",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1473,B1473)","v":"Gliotoxin"},"Gliotoxin","D005912",1,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1474,B1474)","v":"glucose-1-phosphate"},"glucose-1-phosphate","C031590",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1475,B1475)","v":"Glucuronic Acid"},"Glucuronic Acid","D020723",1,0,6,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1476,B1476)","v":"glycero-3-phosphoinositol 4-phosphate"},"glycero-3-phosphoinositol 4-phosphate","C062528",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1477,B1477)","v":"glycerylphosphoinositol"},"glycerylphosphoinositol","C014575",1,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1478,B1478)","v":"Griseofulvin"},"Griseofulvin","D006118",1,1,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1479,B1479)","v":"GSK525762A"},"GSK525762A","C554645",1,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1480,B1480)","v":"guanidinosuccinic acid"},"guanidinosuccinic acid","C001318",1,0,0,18,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1481,B1481)","v":"gung-gui-tang"},"gung-gui-tang","C494611",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1482,B1482)","v":"Harmaline"},"Harmaline","D006246",1,0,0,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1483,B1483)","v":"Hexobarbital"},"Hexobarbital","D006591",1,0,12,22,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1484,B1484)","v":"histocompatibility antigens RT, rat"},"histocompatibility antigens RT, rat","C038353",1,0,0,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1485,B1485)","v":"Homogentisic Acid"},"Homogentisic Acid","D006713",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1486,B1486)","v":"hydrazine"},"hydrazine","C029424",1,2,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1487,B1487)","v":"hydroxyethyl methacrylate"},"hydroxyethyl methacrylate","C005044",1,0,0,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1488,B1488)","v":"hygromycin A"},"hygromycin A","C026273",1,0,0,24,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1489,B1489)","v":"Hypoxanthine"},"Hypoxanthine","D019271",1,0,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1490,B1490)","v":"I Blood-Group System"},"I Blood-Group System","D007048",1,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1491,B1491)","v":"incomplete Freund's adjuvant"},"incomplete Freund's adjuvant","C114843",1,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1492,B1492)","v":"indium oxine"},"indium oxine","C032950",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1493,B1493)","v":"indolepropionic acid"},"indolepropionic acid","C015292",1,0,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1494,B1494)","v":"Iodipamide"},"Iodipamide","D007458",1,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1495,B1495)","v":"iodoalphionic acid"},"iodoalphionic acid","C034344",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1496,B1496)","v":"iodofiltic acid"},"iodofiltic acid","C049338",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1497,B1497)","v":"iophenoxic acid"},"iophenoxic acid","C008160",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1498,B1498)","v":"isobutylparaben"},"isobutylparaben","C471067",1,1,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1499,B1499)","v":"Keratan Sulfate"},"Keratan Sulfate","D007632",1,0,2,19,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1500,B1500)","v":"Ketorolac"},"Ketorolac","D020910",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1501,B1501)","v":"laminaran"},"laminaran","C008247",1,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1502,B1502)","v":"lard"},"lard","C029310",1,0,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1503,B1503)","v":"lenvatinib"},"lenvatinib","C531958",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1504,B1504)","v":"leptine I"},"leptine I","C410862",1,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1505,B1505)","v":"Leukotriene B4"},"Leukotriene B4","D007975",1,0,0,48,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1506,B1506)","v":"Levorphanol"},"Levorphanol","D007981",1,0,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1507,B1507)","v":"Lewis Blood-Group System"},"Lewis Blood-Group System","D007983",1,0,0,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1508,B1508)","v":"Linseed Oil"},"Linseed Oil","D008043",1,0,2,33,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1509,B1509)","v":"lipopolysaccharide, E. coli O26-B6"},"lipopolysaccharide, E. coli O26-B6","C433788",1,2,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1510,B1510)","v":"long-acting thyroid stimulator inhibitor"},"long-acting thyroid stimulator inhibitor","C018995",1,4,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1511,B1511)","v":"LR white"},"LR white","C048707",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1512,B1512)","v":"lymph node revealing solution"},"lymph node revealing solution","C119829",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1513,B1513)","v":"lysophosphatidic acid"},"lysophosphatidic acid","C032881",1,0,0,140,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1514,B1514)","v":"maitotoxin"},"maitotoxin","C020394",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1515,B1515)","v":"mandelic acid"},"mandelic acid","C037938",1,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1516,B1516)","v":"Mannitol"},"Mannitol","D008353",1,0,2,29,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1517,B1517)","v":"margaric acid"},"margaric acid","C013102",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1518,B1518)","v":"maxacalcitol"},"maxacalcitol","C051883",1,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1519,B1519)","v":"meglumine antimoniate"},"meglumine antimoniate","C005278",1,0,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1520,B1520)","v":"menadiol"},"menadiol","C023885",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1521,B1521)","v":"mercaptobenzimidazol"},"mercaptobenzimidazol","C434503",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1522,B1522)","v":"metaperiodate"},"metaperiodate","C009288",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1523,B1523)","v":"Methenamine"},"Methenamine","D008709",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1524,B1524)","v":"Methotrimeprazine"},"Methotrimeprazine","D008728",1,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1525,B1525)","v":"methoxytryptophol"},"methoxytryptophol","C002465",1,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1526,B1526)","v":"methyl 4-((8-((5-chloro-2-methoxyphenyl)amino)-5,6-dihydro-4H-cyclohepta(1,2-d-3,4-d')bis(thiazole)-2-yl)amino)-4-oxobutanoate"},"methyl 4-((8-((5-chloro-2-methoxyphenyl)amino)-5,6-dihydro-4H-cyclohepta(1,2-d-3,4-d')bis(thiazole)-2-yl)amino)-4-oxobutanoate","C000595002",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1527,B1527)","v":"Methyldimethylaminoazobenzene"},"Methyldimethylaminoazobenzene","D008749",1,0,2,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1528,B1528)","v":"Mitomycin"},"Mitomycin","D016685",1,0,0,40,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1529,B1529)","v":"N-(4-iodophenethyl)maleimide"},"N-(4-iodophenethyl)maleimide","C074012",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1530,B1530)","v":"N-(9-((5-chloro-2-methoxyphenyl)amino)-4,5,6,7-tetrahydrocycloocta(1,2-d-3,4-d')bis(thiazole)-2-yl)isobutyramide"},"N-(9-((5-chloro-2-methoxyphenyl)amino)-4,5,6,7-tetrahydrocycloocta(1,2-d-3,4-d')bis(thiazole)-2-yl)isobutyramide","C000595003",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1531,B1531)","v":"N,N,N',N'-tetramethyl-4,4'-methylenedianiline"},"N,N,N',N'-tetramethyl-4,4'-methylenedianiline","C035472",1,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1532,B1532)","v":"N-acetylglucosamine-6-sulfate"},"N-acetylglucosamine-6-sulfate","C033137",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1533,B1533)","v":"N-acetylglucosaminylasparagine"},"N-acetylglucosaminylasparagine","C000009",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1534,B1534)","v":"Nalorphine"},"Nalorphine","D009269",1,0,0,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1535,B1535)","v":"Naphazoline"},"Naphazoline","D009278",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1536,B1536)","v":"Nitroblue Tetrazolium"},"Nitroblue Tetrazolium","D009580",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1537,B1537)","v":"normosol R"},"normosol R","C017577",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1538,B1538)","v":"N-succinimidyl 4-hydroxy-3-iodobenzoate"},"N-succinimidyl 4-hydroxy-3-iodobenzoate","C079702",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1539,B1539)","v":"N-succinimidyl-2,4-dimethoxy-3-(tributylstannyl)benzoate"},"N-succinimidyl-2,4-dimethoxy-3-(tributylstannyl)benzoate","C069574",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1540,B1540)","v":"N-succinimidyl-2,4-dimethoxy-3-(trimethylstannyl)benzoate"},"N-succinimidyl-2,4-dimethoxy-3-(trimethylstannyl)benzoate","C069573",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1541,B1541)","v":"N-succinimidyl-2,4-dimethoxy-3-iodobenzoate"},"N-succinimidyl-2,4-dimethoxy-3-iodobenzoate","C069575",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1542,B1542)","v":"oligoganglioside G(M1)"},"oligoganglioside G(M1)","C030332",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1543,B1543)","v":"Oxyquinoline"},"Oxyquinoline","D015125",1,0,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1544,B1544)","v":"PBB 153"},"PBB 153","C533857",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1545,B1545)","v":"PD 161570"},"PD 161570","C107527",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1546,B1546)","v":"PD 166866"},"PD 166866","C113399",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1547,B1547)","v":"Peanut Oil"},"Peanut Oil","D000074241",1,1,2,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1548,B1548)","v":"pemirolast"},"pemirolast","C055139",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1549,B1549)","v":"pendimethalin"},"pendimethalin","C030856",1,0,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1550,B1550)","v":"penta-O-ethylquercetin"},"penta-O-ethylquercetin","C057450",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1551,B1551)","v":"perfluorononanoic acid"},"perfluorononanoic acid","C584865",1,1,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1552,B1552)","v":"perfluorooctane"},"perfluorooctane","C073608",1,0,2,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1553,B1553)","v":"Phenmetrazine"},"Phenmetrazine","D010633",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1554,B1554)","v":"phenylamil"},"phenylamil","C047088",1,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1555,B1555)","v":"Phenylmethylsulfonyl Fluoride"},"Phenylmethylsulfonyl Fluoride","D010664",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1556,B1556)","v":"phenylpyruvic acid"},"phenylpyruvic acid","C031606",1,1,6,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1557,B1557)","v":"phorbolol myristate acetate"},"phorbolol myristate acetate","C016658",1,0,0,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1558,B1558)","v":"phosphatidal ethanolamines"},"phosphatidal ethanolamines","C020791",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1559,B1559)","v":"phosphatidylethanol"},"phosphatidylethanol","C051521",1,0,0,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1560,B1560)","v":"phosphoric acid"},"phosphoric acid","C030242",1,0,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1561,B1561)","v":"Phytol"},"Phytol","D010836",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1562,B1562)","v":"phytosphingosine"},"phytosphingosine","C012491",1,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1563,B1563)","v":"pipecolic acid"},"pipecolic acid","C031345",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1564,B1564)","v":"PN 202-791"},"PN 202-791","C049834",1,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1565,B1565)","v":"polyisoprenyl-beta-D-mannopyranosyl phosphates"},"polyisoprenyl-beta-D-mannopyranosyl phosphates","C011081",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1566,B1566)","v":"polysialic acid"},"polysialic acid","C021319",1,0,2,53,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1567,B1567)","v":"Potassium Permanganate"},"Potassium Permanganate","D011196",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1568,B1568)","v":"Prilocaine"},"Prilocaine","D011318",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1569,B1569)","v":"prolonium"},"prolonium","C036108",1,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1570,B1570)","v":"propacetamol"},"propacetamol","C063776",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1571,B1571)","v":"propylene"},"propylene","C013658",1,6,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1572,B1572)","v":"propylene oxide"},"propylene oxide","C009068",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1573,B1573)","v":"propylparaben"},"propylparaben","C006068",1,1,2,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1574,B1574)","v":"Prospidium"},"Prospidium","D011447",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1575,B1575)","v":"prostaglandin F2beta"},"prostaglandin F2beta","C037027",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1576,B1576)","v":"Prostaglandins E, Synthetic"},"Prostaglandins E, Synthetic","D011459",1,0,4,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1577,B1577)","v":"Prostaglandins F, Synthetic"},"Prostaglandins F, Synthetic","D011461",1,1,6,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1578,B1578)","v":"protoporphyrin IX"},"protoporphyrin IX","C028025",1,0,0,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1579,B1579)","v":"Pyrilamine"},"Pyrilamine","D011738",1,0,0,28,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1580,B1580)","v":"ramosetron"},"ramosetron","C071315",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1581,B1581)","v":"Retinaldehyde"},"Retinaldehyde","D012172",1,0,2,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1582,B1582)","v":"Rhamnose"},"Rhamnose","D012210",1,1,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1583,B1583)","v":"Rh-Hr Blood-Group System"},"Rh-Hr Blood-Group System","D012204",1,0,0,30,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1584,B1584)","v":"Ringer's acetate"},"Ringer's acetate","C028570",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1585,B1585)","v":"Romanowsky-Giemsa stain"},"Romanowsky-Giemsa stain","C046541",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1586,B1586)","v":"roquinimex"},"roquinimex","C045282",1,0,0,9,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1587,B1587)","v":"Saccharin"},"Saccharin","D012439",1,0,2,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1588,B1588)","v":"Safflower Oil"},"Safflower Oil","D012450",1,0,2,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1589,B1589)","v":"safingol"},"safingol","C005682",1,0,0,15,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1590,B1590)","v":"Sephacryl Superfine"},"Sephacryl Superfine","C037239",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1591,B1591)","v":"sodium chromate(VI)"},"sodium chromate(VI)","C028982",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1592,B1592)","v":"sodium cyanate"},"sodium cyanate","C009281",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1593,B1593)","v":"sodium ethoxide"},"sodium ethoxide","C098088",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1594,B1594)","v":"sodium thiocyanate"},"sodium thiocyanate","C024553",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1595,B1595)","v":"S-phenethylformamidino-4-(N-ethylisothioamide)morpholine"},"S-phenethylformamidino-4-(N-ethylisothioamide)morpholine","C039808",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1596,B1596)","v":"Spiramycin"},"Spiramycin","D015572",1,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1597,B1597)","v":"Starch"},"Starch","D013213",1,0,8,48,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1598,B1598)","v":"Steam"},"Steam","D013227",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1599,B1599)","v":"stilbamidine"},"stilbamidine","C042560",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1600,B1600)","v":"sulfacrylate"},"sulfacrylate","C036516",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1601,B1601)","v":"Sulfalene"},"Sulfalene","D013415",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1602,B1602)","v":"Sulfisoxazole"},"Sulfisoxazole","D013444",1,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1603,B1603)","v":"Sulfobromophthalein"},"Sulfobromophthalein","D013448",1,2,10,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1604,B1604)","v":"T-2 Toxin"},"T-2 Toxin","D013605",1,0,2,30,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1605,B1605)","v":"Taurocholic Acid"},"Taurocholic Acid","D013656",1,2,4,19,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1606,B1606)","v":"t-butyloxycarbonyl group"},"t-butyloxycarbonyl group","C000345",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1607,B1607)","v":"technetium 99m EDDA-HYNIC-Tyr(3)-octreotide"},"technetium 99m EDDA-HYNIC-Tyr(3)-octreotide","C487389",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1608,B1608)","v":"technetium phytate"},"technetium phytate","C026177",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1609,B1609)","v":"technetium Tc 99m benzoylethylenediamine-N,N-diacetic acid"},"technetium Tc 99m benzoylethylenediamine-N,N-diacetic acid","C031124",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1610,B1610)","v":"technetium Tc 99m diphosphonate"},"technetium Tc 99m diphosphonate","C029045",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1611,B1611)","v":"technetium Tc 99m etidronate"},"technetium Tc 99m etidronate","C019561",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1612,B1612)","v":"technetium Tc 99m gluceptate"},"technetium Tc 99m gluceptate","C100014",1,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1613,B1613)","v":"technetium Tc 99m hexakis(tert-butylisonitrile)"},"technetium Tc 99m hexakis(tert-butylisonitrile)","C043714",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1614,B1614)","v":"technetium Tc 99m hydroxymethylene diphosphonate"},"technetium Tc 99m hydroxymethylene diphosphonate","C024226",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1615,B1615)","v":"Technetium Tc 99m Sulfur Colloid"},"Technetium Tc 99m Sulfur Colloid","D013671",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1616,B1616)","v":"Tenofovir"},"Tenofovir","D000068698",1,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1617,B1617)","v":"thiazosulfone"},"thiazosulfone","C009453",1,2,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1618,B1618)","v":"thiobarbital"},"thiobarbital","C009457",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1619,B1619)","v":"thionine"},"thionine","C009469",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1620,B1620)","v":"Thiram"},"Thiram","D013893",1,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1621,B1621)","v":"thorium nitrate"},"thorium nitrate","C036680",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1622,B1622)","v":"Timolol"},"Timolol","D013999",1,0,0,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1623,B1623)","v":"tranilast"},"tranilast","C012293",1,0,0,17,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1624,B1624)","v":"Trichloroacetic Acid"},"Trichloroacetic Acid","D014238",1,0,2,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1625,B1625)","v":"tridihexethyl"},"tridihexethyl","C005386",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1626,B1626)","v":"Triflupromazine"},"Triflupromazine","D014273",1,2,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1627,B1627)","v":"Trimecaine"},"Trimecaine","D014288",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1628,B1628)","v":"Tripelennamine"},"Tripelennamine","D014309",1,0,0,8,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1629,B1629)","v":"Tromethamine"},"Tromethamine","D014325",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1630,B1630)","v":"tyloxapol"},"tyloxapol","C016811",1,1,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1631,B1631)","v":"UACA antigen"},"UACA antigen","C422446",1,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1632,B1632)","v":"ubiquinol"},"ubiquinol","C003741",1,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1633,B1633)","v":"Vanilmandelic Acid"},"Vanilmandelic Acid","D014642",1,1,6,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1634,B1634)","v":"vemurafenib"},"vemurafenib","C551177",1,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1635,B1635)","v":"VX680"},"VX680","C484810",1,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1636,B1636)","v":"Wy 13876"},"Wy 13876","C012139",1,0,2,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1637,B1637)","v":"Xanthine"},"Xanthine","D019820",1,0,2,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1638,B1638)","v":"Zami 1327"},"Zami 1327","C028476",1,0,0,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1639,B1639)","v":"Zymosan"},"Zymosan","D015054",1,1,2,19,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1640,B1640)","v":"donepezil"},"donepezil","C076946",0,4,4,248,274]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1641,B1641)","v":"Scopolamine Hydrobromide"},"Scopolamine Hydrobromide","D012601",0,0,0,711,216]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1642,B1642)","v":"Memantine"},"Memantine","D008559",0,0,2,325,158]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1643,B1643)","v":"Risperidone"},"Risperidone","D018967",0,3,8,124,154]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1644,B1644)","v":"Rivastigmine"},"Rivastigmine","D000068836",0,0,0,52,143]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1645,B1645)","v":"Piracetam"},"Piracetam","D010889",0,2,0,386,138]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1646,B1646)","v":"topiramate"},"topiramate","C052342",0,0,2,207,136]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1647,B1647)","v":"Galantamine"},"Galantamine","D005702",0,1,0,180,125]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1648,B1648)","v":"modafinil"},"modafinil","C048833",0,0,0,46,117]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1649,B1649)","v":"Phencyclidine"},"Phencyclidine","D010622",0,0,0,532,108]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1650,B1650)","v":"olanzapine"},"olanzapine","C076029",0,3,10,163,104]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1651,B1651)","v":"Clozapine"},"Clozapine","D003024",0,2,6,384,98]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1652,B1652)","v":"Tacrine"},"Tacrine","D013619",0,0,0,217,76]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1653,B1653)","v":"lamotrigine"},"lamotrigine","C047781",0,0,4,180,70]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1654,B1654)","v":"Quetiapine Fumarate"},"Quetiapine Fumarate","D000069348",0,2,13,113,68]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1655,B1655)","v":"Dizocilpine Maleate"},"Dizocilpine Maleate","D016291",0,2,0,1118,67]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1656,B1656)","v":"Citalopram"},"Citalopram","D015283",0,1,2,423,66]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1657,B1657)","v":"Lorazepam"},"Lorazepam","D008140",0,0,0,44,64]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1658,B1658)","v":"etiracetam"},"etiracetam","C026098",0,0,0,257,62]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1659,B1659)","v":"Ginkgo biloba extract"},"Ginkgo biloba extract","C063170",0,0,0,180,51]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1660,B1660)","v":"Triazolam"},"Triazolam","D014229",0,0,0,14,51]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1661,B1661)","v":"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"},"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632",0,0,0,362,44]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1662,B1662)","v":"Pirenzepine"},"Pirenzepine","D010890",0,0,2,107,44]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1663,B1663)","v":"Aripiprazole"},"Aripiprazole","D000068180",0,0,0,48,42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1664,B1664)","v":"Hydrogen Sulfide"},"Hydrogen Sulfide","D006862",0,0,0,297,36]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1665,B1665)","v":"Flumazenil"},"Flumazenil","D005442",0,0,0,159,34]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1666,B1666)","v":"Atomoxetine Hydrochloride"},"Atomoxetine Hydrochloride","D000069445",0,0,0,20,33]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1667,B1667)","v":"zolpidem"},"zolpidem","C049109",0,0,2,59,33]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1668,B1668)","v":"Cannabidiol"},"Cannabidiol","D002185",0,0,0,138,29]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1669,B1669)","v":"Selegiline"},"Selegiline","D012642",0,0,0,181,28]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1670,B1670)","v":"desflurane"},"desflurane","C053562",0,0,0,20,27]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1671,B1671)","v":"ziprasidone"},"ziprasidone","C092292",0,0,0,15,26]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1672,B1672)","v":"epigallocatechin gallate"},"epigallocatechin gallate","C045651",0,0,4,387,24]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1673,B1673)","v":"huperzine A"},"huperzine A","C050426",0,0,0,124,24]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1674,B1674)","v":"Acetylcarnitine"},"Acetylcarnitine","D000108",0,1,0,174,23]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1675,B1675)","v":"Alprazolam"},"Alprazolam","D000525",0,1,2,28,23]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1676,B1676)","v":"Trihexyphenidyl"},"Trihexyphenidyl","D014282",0,0,0,8,22]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1677,B1677)","v":"candesartan"},"candesartan","C081643",0,0,0,43,20]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1678,B1678)","v":"Varenicline"},"Varenicline","D000068580",0,0,0,22,20]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1679,B1679)","v":"oxybutynin"},"oxybutynin","C005419",0,0,0,2,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1680,B1680)","v":"rasagiline"},"rasagiline","C031967",0,0,0,23,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1681,B1681)","v":"Terfenadine"},"Terfenadine","D016593",0,0,0,11,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1682,B1682)","v":"vortioxetine"},"vortioxetine","C557874",0,0,0,54,19]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1683,B1683)","v":"3-n-butylphthalide"},"3-n-butylphthalide","C027125",0,0,0,62,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1684,B1684)","v":"amiridine"},"amiridine","C049860",0,0,0,18,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1685,B1685)","v":"anastrozole"},"anastrozole","C090450",0,0,0,10,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1686,B1686)","v":"Baclofen"},"Baclofen","D001418",0,1,0,427,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1687,B1687)","v":"melamine"},"melamine","C011907",0,0,2,61,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1688,B1688)","v":"Sodium Oxybate"},"Sodium Oxybate","D012978",0,0,0,110,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1689,B1689)","v":"telmisartan"},"telmisartan","C084178",0,0,0,98,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1690,B1690)","v":"tiagabine"},"tiagabine","C059205",0,0,0,70,18]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1691,B1691)","v":"Glycerylphosphorylcholine"},"Glycerylphosphorylcholine","D005997",0,0,0,46,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1692,B1692)","v":"Guanfacine"},"Guanfacine","D016316",0,0,0,2,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1693,B1693)","v":"Mecamylamine"},"Mecamylamine","D008464",0,0,0,22,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1694,B1694)","v":"Methylazoxymethanol Acetate"},"Methylazoxymethanol Acetate","D008746",0,0,0,167,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1695,B1695)","v":"Soman"},"Soman","D012999",0,0,0,228,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1696,B1696)","v":"sultopride"},"sultopride","C012052",0,0,0,6,17]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1697,B1697)","v":"Atenolol"},"Atenolol","D001262",0,10,10,6,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1698,B1698)","v":"Losartan"},"Losartan","D019808",0,3,2,120,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1699,B1699)","v":"zonisamide"},"zonisamide","C022189",0,1,0,84,16]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1700,B1700)","v":"3-(2,4-dimethoxybenzylidene)anabaseine"},"3-(2,4-dimethoxybenzylidene)anabaseine","C088936",0,0,0,27,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1701,B1701)","v":"Actovegin"},"Actovegin","C015646",0,0,2,14,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1702,B1702)","v":"Dacarbazine"},"Dacarbazine","D003606",0,1,0,11,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1703,B1703)","v":"Fenfluramine"},"Fenfluramine","D005277",0,0,2,129,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1704,B1704)","v":"latrepirdine"},"latrepirdine","C010119",0,0,0,6,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1705,B1705)","v":"Lurasidone Hydrochloride"},"Lurasidone Hydrochloride","D000069056",0,0,0,33,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1706,B1706)","v":"oxiracetam"},"oxiracetam","C040619",0,0,0,34,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1707,B1707)","v":"Perindopril"},"Perindopril","D020913",0,0,0,16,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1708,B1708)","v":"reboxetine"},"reboxetine","C074679",0,0,0,60,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1709,B1709)","v":"Venlafaxine Hydrochloride"},"Venlafaxine Hydrochloride","D000069470",0,2,0,144,15]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1710,B1710)","v":"Biperiden"},"Biperiden","D001712",0,0,0,4,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1711,B1711)","v":"Ceftriaxone"},"Ceftriaxone","D002443",0,0,0,70,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1712,B1712)","v":"cilostazol"},"cilostazol","C045645",0,0,0,53,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1713,B1713)","v":"emoxypine succinate"},"emoxypine succinate","C070020",0,0,0,26,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1714,B1714)","v":"Loratadine"},"Loratadine","D017336",0,0,2,1,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1715,B1715)","v":"phenylmethylpyrazolone"},"phenylmethylpyrazolone","C005435",0,0,0,111,14]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1716,B1716)","v":"Crack Cocaine"},"Crack Cocaine","D016578",0,0,0,4,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1717,B1717)","v":"Duloxetine Hydrochloride"},"Duloxetine Hydrochloride","D000068736",0,0,0,70,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1718,B1718)","v":"fexofenadine"},"fexofenadine","C093230",0,0,0,11,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1719,B1719)","v":"Flurazepam"},"Flurazepam","D005479",0,0,0,68,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1720,B1720)","v":"Medical Marijuana"},"Medical Marijuana","D064086",0,0,0,0,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1721,B1721)","v":"pramipexole"},"pramipexole","C061333",0,0,0,28,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1722,B1722)","v":"Sarin"},"Sarin","D012524",0,0,0,40,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1723,B1723)","v":"temozolomide"},"temozolomide","C047246",0,1,0,11,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1724,B1724)","v":"tempol"},"tempol","C001803",0,0,4,25,13]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1725,B1725)","v":"Cetirizine"},"Cetirizine","D017332",0,0,0,3,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1726,B1726)","v":"Thioridazine"},"Thioridazine","D013881",0,2,2,10,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1727,B1727)","v":"tianeptine"},"tianeptine","C050504",0,0,0,158,12]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1728,B1728)","v":"4-Aminopyridine"},"4-Aminopyridine","D015761",0,0,0,427,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1729,B1729)","v":"Ibuprofen"},"Ibuprofen","D007052",0,0,0,78,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1730,B1730)","v":"idebenone"},"idebenone","C036619",0,0,0,53,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1731,B1731)","v":"Methylmalonic Acid"},"Methylmalonic Acid","D008764",0,2,0,8,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1732,B1732)","v":"Pregnanolone"},"Pregnanolone","D011280",0,1,0,455,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1733,B1733)","v":"sesamol"},"sesamol","C025583",0,0,0,5,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1734,B1734)","v":"Sildenafil Citrate"},"Sildenafil Citrate","D000068677",0,0,0,94,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1735,B1735)","v":"Trazodone"},"Trazodone","D014196",0,0,0,16,11]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1736,B1736)","v":"3-nitropropionic acid"},"3-nitropropionic acid","C015392",0,0,0,142,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1737,B1737)","v":"Adamantane"},"Adamantane","D000218",0,0,0,120,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1738,B1738)","v":"armodafinil"},"armodafinil","C579652",0,0,0,0,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1739,B1739)","v":"Bupropion"},"Bupropion","D016642",0,0,4,34,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1740,B1740)","v":"Chlorpheniramine"},"Chlorpheniramine","D002744",0,0,0,13,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1741,B1741)","v":"ispronicline"},"ispronicline","C490152",0,0,0,2,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1742,B1742)","v":"linopirdine"},"linopirdine","C061017",0,0,0,20,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1743,B1743)","v":"Methohexital"},"Methohexital","D008723",0,0,0,20,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1744,B1744)","v":"milnacipran"},"milnacipran","C048107",0,0,0,33,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1745,B1745)","v":"nefiracetam"},"nefiracetam","C058876",0,0,0,66,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1746,B1746)","v":"Nicardipine"},"Nicardipine","D009529",0,0,0,42,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1747,B1747)","v":"oxaliplatin"},"oxaliplatin","C030110",0,2,0,35,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1748,B1748)","v":"Pergolide"},"Pergolide","D010479",0,0,0,6,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1749,B1749)","v":"Phenylpropanolamine"},"Phenylpropanolamine","D010665",0,0,0,8,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1750,B1750)","v":"Solifenacin Succinate"},"Solifenacin Succinate","D000069464",0,0,0,0,10]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1751,B1751)","v":"Aluminum Hydroxide"},"Aluminum Hydroxide","D000536",0,0,4,10,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1752,B1752)","v":"Dextromethorphan"},"Dextromethorphan","D003915",0,0,0,97,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1753,B1753)","v":"DM 235"},"DM 235","C416655",0,0,0,8,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1754,B1754)","v":"eprosartan"},"eprosartan","C068373",0,0,0,8,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1755,B1755)","v":"ginsenoside Rg1"},"ginsenoside Rg1","C035054",0,0,0,187,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1756,B1756)","v":"Moclobemide"},"Moclobemide","D020912",0,1,0,14,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1757,B1757)","v":"naringin"},"naringin","C005274",0,1,0,44,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1758,B1758)","v":"propionic acid"},"propionic acid","C029658",0,0,4,30,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1759,B1759)","v":"rhodioloside"},"rhodioloside","C009172",0,0,0,59,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1760,B1760)","v":"sertindole"},"sertindole","C066304",0,0,0,8,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1761,B1761)","v":"sodium bisulfide"},"sodium bisulfide","C025451",0,0,0,32,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1762,B1762)","v":"sulthiame"},"sulthiame","C084593",0,0,0,6,9]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1763,B1763)","v":"3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole"},"3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","C088383",0,0,0,8,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1764,B1764)","v":"Acyclovir"},"Acyclovir","D000212",0,0,0,14,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1765,B1765)","v":"Capsaicin"},"Capsaicin","D002211",0,3,0,148,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1766,B1766)","v":"choto-san"},"choto-san","C120250",0,0,0,14,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1767,B1767)","v":"darifenacin"},"darifenacin","C101207",0,0,0,0,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1768,B1768)","v":"Deferoxamine"},"Deferoxamine","D003676",0,2,0,102,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1769,B1769)","v":"Harmine"},"Harmine","D006247",0,0,0,54,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1770,B1770)","v":"Hydroxyzine"},"Hydroxyzine","D006919",0,0,0,9,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1771,B1771)","v":"Ibotenic Acid"},"Ibotenic Acid","D007051",0,0,0,369,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1772,B1772)","v":"methylazoxymethanol"},"methylazoxymethanol","C030667",0,0,0,94,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1773,B1773)","v":"nitisinone"},"nitisinone","C077073",0,0,0,0,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1774,B1774)","v":"oleuropein"},"oleuropein","C002769",0,0,0,14,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1775,B1775)","v":"Oxazepam"},"Oxazepam","D010076",0,0,0,18,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1776,B1776)","v":"Pentoxifylline"},"Pentoxifylline","D010431",0,0,0,86,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1777,B1777)","v":"Pyrithioxin"},"Pyrithioxin","D011746",0,0,0,0,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1778,B1778)","v":"Pyruvaldehyde"},"Pyruvaldehyde","D011765",0,0,0,71,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1779,B1779)","v":"Remoxipride"},"Remoxipride","D017330",0,0,0,0,8]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1780,B1780)","v":"1-Naphthylamine"},"1-Naphthylamine","D015057",0,0,4,10,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1781,B1781)","v":"Alfentanil"},"Alfentanil","D015760",0,0,0,4,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1782,B1782)","v":"Amlodipine"},"Amlodipine","D017311",0,0,0,40,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1783,B1783)","v":"baicalein"},"baicalein","C006680",0,0,0,71,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1784,B1784)","v":"benphothiamine"},"benphothiamine","C013835",0,0,0,8,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1785,B1785)","v":"blonanserin"},"blonanserin","C079310",0,0,0,4,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1786,B1786)","v":"Clonazepam"},"Clonazepam","D002998",0,1,0,42,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1787,B1787)","v":"clopidogrel"},"clopidogrel","C055162",0,0,0,36,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1788,B1788)","v":"danggui-shaoyao-san"},"danggui-shaoyao-san","C531150",0,0,0,22,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1789,B1789)","v":"ethylcholine aziridinium"},"ethylcholine aziridinium","C044894",0,0,0,334,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1790,B1790)","v":"Hesperidin"},"Hesperidin","D006569",0,0,0,81,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1791,B1791)","v":"icariin"},"icariin","C056599",0,0,2,124,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1792,B1792)","v":"imidafenacin"},"imidafenacin","C120953",0,0,0,0,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1793,B1793)","v":"Indapamide"},"Indapamide","D007190",0,0,0,0,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1794,B1794)","v":"N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide"},"N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide","C090413",0,0,0,153,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1795,B1795)","v":"N,N-Dimethyltryptamine"},"N,N-Dimethyltryptamine","D004130",0,0,0,6,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1796,B1796)","v":"olmesartan"},"olmesartan","C437965",0,0,0,25,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1797,B1797)","v":"Oxidopamine"},"Oxidopamine","D016627",0,0,0,217,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1798,B1798)","v":"PBT2 compound"},"PBT2 compound","C531955",0,0,0,10,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1799,B1799)","v":"Phosphamidon"},"Phosphamidon","D010707",0,0,4,0,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1800,B1800)","v":"PNU-282987"},"PNU-282987","C498513",0,0,0,10,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1801,B1801)","v":"pozanicline"},"pozanicline","C108326",0,0,0,4,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1802,B1802)","v":"pycnogenols"},"pycnogenols","C024070",0,0,0,22,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1803,B1803)","v":"Quinpirole"},"Quinpirole","D019257",0,0,0,60,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1804,B1804)","v":"Rosuvastatin Calcium"},"Rosuvastatin Calcium","D000068718",0,1,0,51,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1805,B1805)","v":"Sumatriptan"},"Sumatriptan","D018170",0,0,0,16,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1806,B1806)","v":"Ticlopidine"},"Ticlopidine","D013988",0,0,0,38,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1807,B1807)","v":"Tolterodine Tartrate"},"Tolterodine Tartrate","D000068737",0,0,0,0,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1808,B1808)","v":"ursolic acid"},"ursolic acid","C005466",0,0,0,42,7]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1809,B1809)","v":"11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid"},"11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid","C016780",0,0,0,0,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1810,B1810)","v":"2-((2-morpholino)ethylthio)-5-ethoxybenzimidazole"},"2-((2-morpholino)ethylthio)-5-ethoxybenzimidazole","C410924",0,0,0,8,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1811,B1811)","v":"24-hydroxycholesterol"},"24-hydroxycholesterol","C044563",0,0,0,32,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1812,B1812)","v":"7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole"},"7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole","C000591008",0,0,0,2,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1813,B1813)","v":"aniracetam"},"aniracetam","C036466",0,0,0,76,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1814,B1814)","v":"brexpiprazole"},"brexpiprazole","C000591922",0,0,0,0,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1815,B1815)","v":"crocin"},"crocin","C029036",0,0,0,32,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1816,B1816)","v":"cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester"},"cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester","C500528",0,0,0,32,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1817,B1817)","v":"domoic acid"},"domoic acid","C012301",0,0,4,259,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1818,B1818)","v":"Ethosuximide"},"Ethosuximide","D005013",0,0,0,26,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1819,B1819)","v":"Finasteride"},"Finasteride","D018120",0,1,2,34,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1820,B1820)","v":"gastrodin"},"gastrodin","C045345",0,0,0,67,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1821,B1821)","v":"glyceryl 2-arachidonate"},"glyceryl 2-arachidonate","C094503",0,0,0,200,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1822,B1822)","v":"Grape Seed Extract"},"Grape Seed Extract","D056604",0,0,0,66,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1823,B1823)","v":"Hydromorphone"},"Hydromorphone","D004091",0,0,0,0,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1824,B1824)","v":"Hydroxyethylrutoside"},"Hydroxyethylrutoside","D006896",0,0,0,29,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1825,B1825)","v":"Isoflurophate"},"Isoflurophate","D007531",0,0,2,86,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1826,B1826)","v":"Linagliptin"},"Linagliptin","D000069476",0,0,0,9,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1827,B1827)","v":"lycopene"},"lycopene","C015329",0,0,0,72,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1828,B1828)","v":"N-methyl-2-(4'-methylaminophenyl)-6-hydroxybenzothiazole"},"N-methyl-2-(4'-methylaminophenyl)-6-hydroxybenzothiazole","C513092",0,0,0,7,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1829,B1829)","v":"Nomifensine"},"Nomifensine","D009627",0,0,0,12,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1830,B1830)","v":"Oleanolic Acid"},"Oleanolic Acid","D009828",0,2,0,165,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1831,B1831)","v":"peoniflorin"},"peoniflorin","C015423",0,0,0,114,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1832,B1832)","v":"phenserine"},"phenserine","C092280",0,0,0,15,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1833,B1833)","v":"piracetam, vinpocetine drug combination"},"piracetam, vinpocetine drug combination","C532690",0,0,0,0,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1834,B1834)","v":"rifaximin"},"rifaximin","C042734",0,0,0,2,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1835,B1835)","v":"S 17092-1"},"S 17092-1","C118986",0,0,0,4,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1836,B1836)","v":"spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one"},"spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one","C511224",0,0,0,22,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1837,B1837)","v":"SSR125543"},"SSR125543","C502407",0,0,0,8,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1838,B1838)","v":"SSR180711"},"SSR180711","C516833",0,0,0,8,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1839,B1839)","v":"troxerutin"},"troxerutin","C005865",0,0,0,28,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1840,B1840)","v":"zopiclone"},"zopiclone","C515050",0,1,0,20,6]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1841,B1841)","v":"1-((4-cyano-4-(pyridine-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid"},"1-((4-cyano-4-(pyridine-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid","C581536",0,0,0,0,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1842,B1842)","v":"1-(3-chlorophenyl)piperazine"},"1-(3-chlorophenyl)piperazine","C015068",0,0,0,38,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1843,B1843)","v":"4-Butyrolactone"},"4-Butyrolactone","D015107",0,0,0,134,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1844,B1844)","v":"5-methyltetrahydrofolate"},"5-methyltetrahydrofolate","C005984",0,0,0,7,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1845,B1845)","v":"6-(4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one"},"6-(4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one","C572323",0,0,0,8,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1846,B1846)","v":"7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo(4,3-b)pyridazine"},"7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo(4,3-b)pyridazine","C507018",0,0,0,0,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1847,B1847)","v":"acamprosate"},"acamprosate","C043877",0,0,0,38,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1848,B1848)","v":"carvacrol"},"carvacrol","C073316",0,0,0,37,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1849,B1849)","v":"carvedilol"},"carvedilol","C043211",0,0,4,37,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1850,B1850)","v":"desloratadine"},"desloratadine","C121345",0,0,2,1,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1851,B1851)","v":"Droperidol"},"Droperidol","D004329",0,0,0,0,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1852,B1852)","v":"Ellagic Acid"},"Ellagic Acid","D004610",0,0,0,22,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1853,B1853)","v":"Flupenthixol"},"Flupenthixol","D005475",0,0,0,4,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1854,B1854)","v":"ginsenoside Re"},"ginsenoside Re","C049864",0,0,0,21,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1855,B1855)","v":"lacosamide"},"lacosamide","C403507",0,0,0,22,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1856,B1856)","v":"ligustilide"},"ligustilide","C027820",0,0,0,13,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1857,B1857)","v":"mephedrone"},"mephedrone","C548233",0,0,0,22,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1858,B1858)","v":"miglustat"},"miglustat","C059896",0,0,0,8,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1859,B1859)","v":"motexafin gadolinium"},"motexafin gadolinium","C437683",0,0,0,0,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1860,B1860)","v":"norclozapine"},"norclozapine","C058272",0,0,0,42,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1861,B1861)","v":"Paliperidone Palmitate"},"Paliperidone Palmitate","D000068882",0,0,0,12,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1862,B1862)","v":"perospirone"},"perospirone","C065533",0,0,0,4,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1863,B1863)","v":"Phenelzine"},"Phenelzine","D010624",0,1,0,21,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1864,B1864)","v":"Phenylethyl Alcohol"},"Phenylethyl Alcohol","D010626",0,0,2,88,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1865,B1865)","v":"piperazine"},"piperazine","C034930",0,0,0,14,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1866,B1866)","v":"Propoxur"},"Propoxur","D001074",0,0,0,0,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1867,B1867)","v":"puerarin"},"puerarin","C033607",0,0,0,122,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1868,B1868)","v":"Quinolinic Acid"},"Quinolinic Acid","D017378",0,0,0,403,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1869,B1869)","v":"Raclopride"},"Raclopride","D020891",0,0,0,17,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1870,B1870)","v":"ramelteon"},"ramelteon","C495910",0,0,4,10,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1871,B1871)","v":"Ramipril"},"Ramipril","D017257",0,1,4,22,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1872,B1872)","v":"Ringer's lactate"},"Ringer's lactate","C029239",0,0,0,6,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1873,B1873)","v":"S 20098"},"S 20098","C084711",0,0,0,103,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1874,B1874)","v":"tandospirone"},"tandospirone","C055267",0,0,0,28,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1875,B1875)","v":"tanshinone"},"tanshinone","C021751",0,0,0,82,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1876,B1876)","v":"Tetrachloroethylene"},"Tetrachloroethylene","D013750",0,0,0,8,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1877,B1877)","v":"Tetraethyl Lead"},"Tetraethyl Lead","D013756",0,0,0,4,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1878,B1878)","v":"tolcapone"},"tolcapone","C066340",0,0,0,4,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1879,B1879)","v":"Tramadol"},"Tramadol","D014147",0,1,0,33,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1880,B1880)","v":"tramiprosate"},"tramiprosate","C001355",0,0,0,8,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1881,B1881)","v":"trichostatin A"},"trichostatin A","C012589",0,0,0,177,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1882,B1882)","v":"velnacrine"},"velnacrine","C056424",0,0,0,4,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1883,B1883)","v":"Voriconazole"},"Voriconazole","D065819",0,0,0,7,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1884,B1884)","v":"xanomeline"},"xanomeline","C075257",0,0,0,12,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1885,B1885)","v":"Yi-Gan San"},"Yi-Gan San","C524644",0,0,0,32,5]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1886,B1886)","v":"(2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine"},"(2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine","C568612",0,0,0,4,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1887,B1887)","v":"11-hydroxy-delta(9)-tetrahydrocannabinol"},"11-hydroxy-delta(9)-tetrahydrocannabinol","C001427",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1888,B1888)","v":"1-methylpiperidine-4-spiro-(2'-methylthiazoline)"},"1-methylpiperidine-4-spiro-(2'-methylthiazoline)","C111926",0,0,0,4,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1889,B1889)","v":"2-(3-(3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl) -8-(3,4,5-trifluorophenoxy)-5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyridin-8-yl)propan-2-ol"},"2-(3-(3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl) -8-(3,4,5-trifluorophenoxy)-5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyridin-8-yl)propan-2-ol","C000613083",0,0,0,4,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1890,B1890)","v":"27-hydroxycholesterol"},"27-hydroxycholesterol","C076996",0,0,0,33,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1891,B1891)","v":"2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione"},"2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione","C001886",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1892,B1892)","v":"3,4-methylenedioxyethamphetamine"},"3,4-methylenedioxyethamphetamine","C051800",0,0,0,15,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1893,B1893)","v":"3-aminopyridine-2-carboxaldehyde thiosemicarbazone"},"3-aminopyridine-2-carboxaldehyde thiosemicarbazone","C078157",0,0,0,4,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1894,B1894)","v":"3-benzenesulfonyl-8-piperazin-1-ylquinoline"},"3-benzenesulfonyl-8-piperazin-1-ylquinoline","C548140",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1895,B1895)","v":"4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride"},"4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride","C119207",0,0,0,4,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1896,B1896)","v":"4-cresol sulfate"},"4-cresol sulfate","C408690",0,0,0,3,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1897,B1897)","v":"4-hydroxy-2-nonenal"},"4-hydroxy-2-nonenal","C027576",0,0,0,148,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1898,B1898)","v":"4-hydroxybutyric acid"},"4-hydroxybutyric acid","C111420",0,0,0,12,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1899,B1899)","v":"ABT-126"},"ABT-126","C000618299",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1900,B1900)","v":"akebia saponin D"},"akebia saponin D","C534004",0,0,0,10,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1901,B1901)","v":"angelicae sinensis extract"},"angelicae sinensis extract","C044613",0,0,0,14,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1902,B1902)","v":"anisodamine"},"anisodamine","C003922",0,0,0,10,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1903,B1903)","v":"asarone"},"asarone","C012195",0,0,0,44,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1904,B1904)","v":"Asenapine"},"Asenapine","C522667",0,0,0,10,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1905,B1905)","v":"benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-"},"benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-","C496397",0,0,0,4,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1906,B1906)","v":"Bromazepam"},"Bromazepam","D001960",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1907,B1907)","v":"Chlorogenic Acid"},"Chlorogenic Acid","D002726",0,2,0,45,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1908,B1908)","v":"Cinnarizine"},"Cinnarizine","D002936",0,0,0,16,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1909,B1909)","v":"Clarithromycin"},"Clarithromycin","D017291",0,0,0,11,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1910,B1910)","v":"Clopenthixol"},"Clopenthixol","D003006",0,0,2,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1911,B1911)","v":"Clorazepate Dipotassium"},"Clorazepate Dipotassium","D003009",0,0,0,12,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1912,B1912)","v":"Clove Oil"},"Clove Oil","D045783",0,0,0,2,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1913,B1913)","v":"Cloxacillin"},"Cloxacillin","D003023",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1914,B1914)","v":"DEET"},"DEET","D003671",0,0,0,10,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1915,B1915)","v":"dihydrexidine"},"dihydrexidine","C061532",0,0,0,6,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1916,B1916)","v":"ebastine"},"ebastine","C058249",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1917,B1917)","v":"Ensaculin"},"Ensaculin","C112452",0,0,0,6,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1918,B1918)","v":"Ethylene Glycol"},"Ethylene Glycol","D019855",0,0,2,7,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1919,B1919)","v":"Etomidate"},"Etomidate","D005045",0,0,0,85,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1920,B1920)","v":"EUK 207"},"EUK 207","C476761",0,0,0,10,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1921,B1921)","v":"Felodipine"},"Felodipine","D015736",0,0,4,2,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1922,B1922)","v":"fisetin"},"fisetin","C017875",0,0,0,52,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1923,B1923)","v":"florbetapir"},"florbetapir","C545186",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1924,B1924)","v":"Flunarizine"},"Flunarizine","D005444",0,2,0,68,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1925,B1925)","v":"Grape Seed Proanthocyanidins"},"Grape Seed Proanthocyanidins","C511402",0,0,0,26,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1926,B1926)","v":"GT 061"},"GT 061","C501053",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1927,B1927)","v":"Hydroxyurea"},"Hydroxyurea","D006918",0,0,0,108,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1928,B1928)","v":"Idazoxan"},"Idazoxan","D019329",0,0,0,47,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1929,B1929)","v":"IDRA 21"},"IDRA 21","C091420",0,0,0,14,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1930,B1930)","v":"imidazenil"},"imidazenil","C082661",0,0,0,12,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1931,B1931)","v":"Indican"},"Indican","D007200",0,0,4,31,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1932,B1932)","v":"kami-untan-to"},"kami-untan-to","C421404",0,0,0,8,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1933,B1933)","v":"Kynurenic Acid"},"Kynurenic Acid","D007736",0,0,0,381,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1934,B1934)","v":"L 158809"},"L 158809","C070967",0,0,0,2,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1935,B1935)","v":"letrozole"},"letrozole","C067431",0,0,0,44,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1936,B1936)","v":"Lisdexamfetamine Dimesylate"},"Lisdexamfetamine Dimesylate","D000069478",0,0,0,4,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1937,B1937)","v":"Lopinavir"},"Lopinavir","D061466",0,0,0,9,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1938,B1938)","v":"mecobalamin"},"mecobalamin","C019476",0,0,0,19,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1939,B1939)","v":"Mefloquine"},"Mefloquine","D015767",0,0,0,19,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1940,B1940)","v":"monomethylpropion"},"monomethylpropion","C047806",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1941,B1941)","v":"N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride"},"N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride","C083832",0,0,0,4,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1942,B1942)","v":"nabilone"},"nabilone","C011941",0,0,0,6,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1943,B1943)","v":"Nalidixic Acid"},"Nalidixic Acid","D009268",0,0,0,6,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1944,B1944)","v":"orientin"},"orientin","C065886",0,0,0,10,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1945,B1945)","v":"oxymethacil"},"oxymethacil","C003029",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1946,B1946)","v":"Oxymorphone"},"Oxymorphone","D010111",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1947,B1947)","v":"perampanel"},"perampanel","C551441",0,0,0,8,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1948,B1948)","v":"physostigmine heptyl"},"physostigmine heptyl","C052450",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1949,B1949)","v":"pifithrin"},"pifithrin","C121565",0,0,0,14,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1950,B1950)","v":"pimagedine"},"pimagedine","C004479",0,0,2,47,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1951,B1951)","v":"pinocembrin"},"pinocembrin","C016063",0,0,0,7,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1952,B1952)","v":"Polyglycolic Acid"},"Polyglycolic Acid","D011100",0,0,6,75,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1953,B1953)","v":"polylactic acid-polyglycolic acid copolymer"},"polylactic acid-polyglycolic acid copolymer","C043435",0,0,6,67,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1954,B1954)","v":"pyrrolidine dithiocarbamic acid"},"pyrrolidine dithiocarbamic acid","C020972",0,0,0,72,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1955,B1955)","v":"remacemide"},"remacemide","C067553",0,0,0,12,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1956,B1956)","v":"rhyncophylline"},"rhyncophylline","C052714",0,0,0,38,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1957,B1957)","v":"Ritonavir"},"Ritonavir","D019438",0,0,4,32,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1958,B1958)","v":"RU 41656"},"RU 41656","C070562",0,0,0,0,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1959,B1959)","v":"scyllitol"},"scyllitol","C009217",0,0,0,10,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1960,B1960)","v":"Secobarbital"},"Secobarbital","D012631",0,0,2,10,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1961,B1961)","v":"Soot"},"Soot","D053260",0,0,0,17,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1962,B1962)","v":"taxane"},"taxane","C080625",0,0,0,2,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1963,B1963)","v":"Technetium Tc 99m Exametazime"},"Technetium Tc 99m Exametazime","D019690",0,2,2,8,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1964,B1964)","v":"Trehalose"},"Trehalose","D014199",0,0,0,23,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1965,B1965)","v":"trimethyltin chloride"},"trimethyltin chloride","C040533",0,0,0,36,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1966,B1966)","v":"vildagliptin"},"vildagliptin","C502012",0,0,0,6,4]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1967,B1967)","v":"1-(quinoxalin-6-ylcarbonyl)piperidine"},"1-(quinoxalin-6-ylcarbonyl)piperidine","C097396",0,0,0,20,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1968,B1968)","v":"2-(4'-(5-methylhexahydropyrrolo(3,4-b)pyrrol-1-yl)biphenyl-4-yl)-2H-pyridazin-3-one"},"2-(4'-(5-methylhexahydropyrrolo(3,4-b)pyrrol-1-yl)biphenyl-4-yl)-2H-pyridazin-3-one","C576396",0,0,0,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1969,B1969)","v":"2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside"},"2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside","C093026",0,0,0,48,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1970,B1970)","v":"2-tert-butylhydroquinone"},"2-tert-butylhydroquinone","C018855",0,0,0,37,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1971,B1971)","v":"3,3'-iminodipropionitrile"},"3,3'-iminodipropionitrile","C008110",0,0,0,30,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1972,B1972)","v":"3,4-dihydroxyphenylethanol"},"3,4-dihydroxyphenylethanol","C005975",0,0,0,25,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1973,B1973)","v":"3-bromo-10-difluoromethyl-9H-imidazo(1,5-a)(1,2,4)triazolo(1,5-d)(1,4)benzodiazepine"},"3-bromo-10-difluoromethyl-9H-imidazo(1,5-a)(1,2,4)triazolo(1,5-d)(1,4)benzodiazepine","C542509",0,0,0,4,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1974,B1974)","v":"5-methoxy-N,N-diisopropyltryptamine"},"5-methoxy-N,N-diisopropyltryptamine","C033696",0,0,0,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1975,B1975)","v":"6,7-dihydroxyflavone"},"6,7-dihydroxyflavone","C485383",0,0,0,57,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1976,B1976)","v":"6-methyl-2-(phenylethynyl)pyridine"},"6-methyl-2-(phenylethynyl)pyridine","C121465",0,0,0,40,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1977,B1977)","v":"7-chloro-N-quinuclidin-3-yl-benzo(b)thiophene-2-carboxamide"},"7-chloro-N-quinuclidin-3-yl-benzo(b)thiophene-2-carboxamide","C573817",0,0,0,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1978,B1978)","v":"8,12-iso-isoprostane F2alpha-VI"},"8,12-iso-isoprostane F2alpha-VI","C115626",0,0,0,2,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1979,B1979)","v":"8-Hydroxy-2-(di-n-propylamino)tetralin"},"8-Hydroxy-2-(di-n-propylamino)tetralin","D017371",0,0,0,404,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1980,B1980)","v":"A-705253"},"A-705253","C500488",0,0,0,14,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1981,B1981)","v":"acetovanillone"},"acetovanillone","C056165",0,0,0,38,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1982,B1982)","v":"acteoside"},"acteoside","C058956",0,0,0,17,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1983,B1983)","v":"adinazolam"},"adinazolam","C039668",0,0,0,8,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1984,B1984)","v":"altinicline maleate"},"altinicline maleate","C100989",0,0,0,4,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1985,B1985)","v":"Amoxapine"},"Amoxapine","D000657",0,0,0,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1986,B1986)","v":"andrographolide"},"andrographolide","C030419",0,0,0,44,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1987,B1987)","v":"Apamin"},"Apamin","D001030",0,0,0,52,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1988,B1988)","v":"asiaticoside"},"asiaticoside","C004446",0,0,0,26,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1989,B1989)","v":"Astemizole"},"Astemizole","D016589",0,0,0,2,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1990,B1990)","v":"atipamezole"},"atipamezole","C050701",0,0,0,15,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1991,B1991)","v":"betulin"},"betulin","C002503",0,1,0,11,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1992,B1992)","v":"brivaracetam"},"brivaracetam","C482793",0,0,0,20,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1993,B1993)","v":"bryostatin 1"},"bryostatin 1","C046785",0,0,0,12,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1994,B1994)","v":"bushen yizhi"},"bushen yizhi","C000604209",0,0,0,4,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1995,B1995)","v":"canertinib dihydrochloride"},"canertinib dihydrochloride","C072383",0,0,0,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1996,B1996)","v":"cariprazine"},"cariprazine","C533287",0,0,0,4,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1997,B1997)","v":"catalpol"},"catalpol","C078040",0,0,0,49,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1998,B1998)","v":"Chenodeoxycholic Acid"},"Chenodeoxycholic Acid","D002635",0,0,4,47,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1999,B1999)","v":"Chewing Gum"},"Chewing Gum","D002638",0,0,0,0,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2000,B2000)","v":"Chitosan"},"Chitosan","D048271",0,0,4,168,3]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2126,B2126)","v":"3-(5-methylisoxazol-3-yl)-6-((1-methyl-1,2,3-triazol-4-yl)methyloxy)-1,2,4-triazolo(3,4-a)phthalazine"},"3-(5-methylisoxazol-3-yl)-6-((1-methyl-1,2,3-triazol-4-yl)methyloxy)-1,2,4-triazolo(3,4-a)phthalazine","C555638",0,0,0,0,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2215,B2215)","v":"ciproxifan"},"ciproxifan","C115705",0,0,0,18,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2282,B2282)","v":"imperatorin"},"imperatorin","C031534",0,0,0,18,2]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2505,B2505)","v":"2-(sec-butyl)-4,5-dihydrothiazole"},"2-(sec-butyl)-4,5-dihydrothiazole","C049351",0,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2532,B2532)","v":"4,4'-diphenylmethane diisocyanate"},"4,4'-diphenylmethane diisocyanate","C005969",0,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2730,B2730)","v":"ibuprofen dimethyl aminoethanol octyl"},"ibuprofen dimethyl aminoethanol octyl","C065129",0,0,0,0,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2914,B2914)","v":"sodium sulfite"},"sodium sulfite","C025026",0,0,0,4,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C2974,B2974)","v":"zolmitriptan"},"zolmitriptan","C089750",0,0,0,6,1]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3164,B3164)","v":"1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine"},"1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine","C410262",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3231,B3231)","v":"12-hydroxy-5,8,10-heptadecatrienoic acid"},"12-hydroxy-5,8,10-heptadecatrienoic acid","C008033",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3429,B3429)","v":"2,2-dimethylbutyric acid"},"2,2-dimethylbutyric acid","C074677",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3439,B3439)","v":"2,3,4-tri-O-acetylarabinopyranosyl isothiocyanate"},"2,3,4-tri-O-acetylarabinopyranosyl isothiocyanate","C041942",0,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3679,B3679)","v":"3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole"},"3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole","C000593290",0,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3746,B3746)","v":"3,5,3',4',5'-pentamethoxystilbene"},"3,5,3',4',5'-pentamethoxystilbene","C494914",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3930,B3930)","v":"4-aminobenzovesamicol"},"4-aminobenzovesamicol","C104300",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4038,B4038)","v":"4-oxy-6-(4-oxybezoyloxy)dauc-8,9-en"},"4-oxy-6-(4-oxybezoyloxy)dauc-8,9-en","C111068",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4180,B4180)","v":"6-(4-hydroxybutyl)-2,3,5-trimethyl-1,4-benzoquinone"},"6-(4-hydroxybutyl)-2,3,5-trimethyl-1,4-benzoquinone","C086107",0,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4247,B4247)","v":"7,8-(methylenedioxy)-14-hydroxyberbane"},"7,8-(methylenedioxy)-14-hydroxyberbane","C048886",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4445,B4445)","v":"alfacalcidol"},"alfacalcidol","C008088",0,3,6,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4503,B4503)","v":"alpha-naphthoflavone"},"alpha-naphthoflavone","C011512",0,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4695,B4695)","v":"atractylenolide III"},"atractylenolide III","C424802",0,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4748,B4748)","v":"Bay Vq 7813"},"Bay Vq 7813","C067180",0,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C4946,B4946)","v":"brazilin"},"brazilin","C044362",0,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5102,B5102)","v":"Carrageenan"},"Carrageenan","D002351",0,0,0,20,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5196,B5196)","v":"chitohexaose"},"chitohexaose","C050523",0,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5394,B5394)","v":"cucurbitane"},"cucurbitane","C514277",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5461,B5461)","v":"dactylorhin B"},"dactylorhin B","C479293",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5567,B5567)","v":"diarctigenin"},"diarctigenin","C532887",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5711,B5711)","v":"DMP 543"},"DMP 543","C112296",0,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5895,B5895)","v":"Ethyldimethylaminopropyl Carbodiimide"},"Ethyldimethylaminopropyl Carbodiimide","D005022",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5962,B5962)","v":"Fenretinide"},"Fenretinide","D017313",0,1,0,25,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C6166,B6166)","v":"ginkgolide B"},"ginkgolide B","C045856",0,0,0,73,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C6212,B6212)","v":"glycoinositolphospholipid, Trypanosoma"},"glycoinositolphospholipid, Trypanosoma","C115336",0,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C6410,B6410)","v":"ICI 118551"},"ICI 118551","C026777",0,0,0,7,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C6477,B6477)","v":"inositol 1,4,5-trisphosphate 1-(2-nitrophenyl)ethyl ester"},"inositol 1,4,5-trisphosphate 1-(2-nitrophenyl)ethyl ester","C061868",0,0,0,3,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C6631,B6631)","v":"karapinchamine B"},"karapinchamine B","C582992",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C6727,B6727)","v":"leiurotoxin I"},"leiurotoxin I","C056574",0,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C6911,B6911)","v":"Mastic Resin"},"Mastic Resin","D000069997",0,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7014,B7014)","v":"methylmercury hydroxide"},"methylmercury hydroxide","C020771",0,0,0,5,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7175,B7175)","v":"N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide"},"N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide","C080955",0,0,0,33,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7359,B7359)","v":"nickel acetate"},"nickel acetate","C119536",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7426,B7426)","v":"N-oleoylethanolamine"},"N-oleoylethanolamine","C033595",0,0,0,1,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7609,B7609)","v":"p-Aminohippuric Acid"},"p-Aminohippuric Acid","D010130",0,3,14,0,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7676,B7676)","v":"perfluorotributylamine"},"perfluorotributylamine","C008807",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7874,B7874)","v":"polyanions"},"polyanions","C009791",0,0,0,10,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C7927,B7927)","v":"poncirin"},"poncirin","C119641",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8078,B8078)","v":"quinoline"},"quinoline","C037219",0,0,0,6,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8191,B8191)","v":"RP 66471"},"RP 66471","C091972",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8375,B8375)","v":"SK&F 83959"},"SK&F 83959","C080703",0,0,0,26,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8442,B8442)","v":"spiradoline"},"spiradoline","C051272",0,0,0,18,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8543,B8543)","v":"SZL 49"},"SZL 49","C051307",0,0,0,4,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8692,B8692)","v":"tiliroside"},"tiliroside","C052083",0,0,0,2,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8890,B8890)","v":"vesamicol"},"vesamicol","C006189",0,0,0,14,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C8943,B8943)","v":"xiaoyao"},"xiaoyao","C516449",0,0,0,12,0]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C9142,B9142)","v":0}]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C9193,B9193)","v":0}]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C9391,B9391)","v":0}]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C9458,B9458)","v":0}]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C9607,B9607)","v":0}]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C9839,B9839)","v":0}]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C9906,B9906)","v":0}]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C10090,B10090)","v":0}]
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["Detail - AOP "]
["Chemical MeSH Name (hyperlinked)","ChemName","chemuid","catord","event_id","event_order","Event Process","Event Action","MeSH term (hyperlinked)","uid","MeSHterm","basescore","Score","Pub Yr","pmid","Title","LinkPMID","aop_id"]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C3,B3)","v":"(+)-JQ1 compound"},"(+)-JQ1 compound","C561695","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J3,K3)","v":"Cognition"},"D003071","Cognition",0,1,2017,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q3,Q3)","v":"29113796"},"The BET/BRD inhibitor JQ1 attenuates diabetes-induced cognitive impairment in rats by targeting Nox4-Nrf2 redox imbalance.","29113796",42]
["(2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine","(2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine","C568612","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27469080","Reducing falls in Parkinson's disease: interactions between donepezil and the 5-HT6 receptor antagonist idalopirdine on falls in a rat model of impaired cognitive control of complex movements.","27469080",42]
["(2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine","(2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine","C568612","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2018,"29318278","Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials.","29318278",42]
["(2R,3S)-pinobanksin-3-cinnamate","(2R,3S)-pinobanksin-3-cinnamate","C000591505","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25808015","(2R,3S)-Pinobanksin-3-cinnamate improves cognition and reduces oxidative stress in rats with vascular dementia.","25808015",42]
["(3,3-dibenzylimidazo(1,2-a)pyridin-2-(3H)-one)","(3,3-dibenzylimidazo(1,2-a)pyridin-2-(3H)-one)","C464538","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11885975","Ameliorative effects of azaindolizinone derivative ZSET845 on scopolamine-induced deficits in passive avoidance and radial-arm maze learning in the rat.","11885975",42]
["(3-aminopropyl)(n-butyl)phosphinic acid","(3-aminopropyl)(n-butyl)phosphinic acid","C079148","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17467069","Strain-dependent effects of SGS742 in the mouse.","17467069",42]
["(4-(2-chlorophenyl-4-fluoro-1-piperidinyl)(5-(1H-pyrazol-4-yl)-3-thienyl)methanone","(4-(2-chlorophenyl-4-fluoro-1-piperidinyl)(5-(1H-pyrazol-4-yl)-3-thienyl)methanone","C000601250","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26305888","Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease.","26305888",42]
["(4-isopropylpiperazin-1-yl)(6-(tetrahydro-2H-pyran-4-yl)-6-azaspiro(2.5)octan-1-yl)methanone","(4-isopropylpiperazin-1-yl)(6-(tetrahydro-2H-pyran-4-yl)-6-azaspiro(2.5)octan-1-yl)methanone","C587723","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24410637","Discovery of spirofused piperazine and diazepane amides as selective histamine-3 antagonists with in vivo efficacy in a mouse model of cognition.","24410637",42]
["(6-chloro-1-(2-(dimethylamino)ethyl)indol-3-yl)-spiro(1H-isobenzofuran-3,4'-piperidine)-1'-yl-methanone","(6-chloro-1-(2-(dimethylamino)ethyl)indol-3-yl)-spiro(1H-isobenzofuran-3,4'-piperidine)-1'-yl-methanone","C000598571","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27711048","A Single Dose, Randomized, Controlled Proof-Of-Mechanism Study of a Novel Vasopressin 1a Receptor Antagonist (RG7713) in High-Functioning Adults with Autism Spectrum Disorder.","27711048",42]
["(N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamate","(N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamate","C423264","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23325108","Dose-dependent effects of ladostigil on microglial activation and cognition in aged rats.","23325108",42]
["(S)-(1-azabicyclo(2.2.2)oct-3-yl)carbamic acid (S)-1-(2-fluorophenyl) ethyl ester","(S)-(1-azabicyclo(2.2.2)oct-3-yl)carbamic acid (S)-1-(2-fluorophenyl) ethyl ester","C520400","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18793655","The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain.","18793655",42]
["(S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro(4.5)decan-3-one","(S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro(4.5)decan-3-one","C470586","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12212772","AF150(S) and AF267B: M1 muscarinic agonists as innovative therapies for Alzheimer's disease.","12212772",42]
["027075 compound","027075 compound","C000620092","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26773200","D5 receptor agonist 027075 promotes cognitive function recovery and neurogenesis in a Aβ1-42-induced mouse model.","26773200",42]
["1-((3-benzyl-3-methyl-2,3-dihydro-1-benzofuran-6-yl)carbonyl)piperidine","1-((3-benzyl-3-methyl-2,3-dihydro-1-benzofuran-6-yl)carbonyl)piperidine","C534147","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22795792","Activation of the CB2 receptor system reverses amyloid-induced memory deficiency.","22795792",42]
["1-((4-cyano-4-(pyridine-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid","1-((4-cyano-4-(pyridine-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid","C581536","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22825578","The muscarinic M1 receptor positive allosteric modulator PQCA improves cognitive measures in rat, cynomolgus macaque, and rhesus macaque.","22825578",42]
["1-((4-cyano-4-(pyridine-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid","1-((4-cyano-4-(pyridine-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid","C581536","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25491927","Improved cognition without adverse effects: novel M1 muscarinic potentiator compares favorably to donepezil and xanomeline in rhesus monkey.","25491927",42]
["1-((4-cyano-4-(pyridine-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid","1-((4-cyano-4-(pyridine-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid","C581536","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26446308","The M1 Muscarinic Positive Allosteric Modulator PQCA Improves Performance on Translatable Tests of Memory and Attention in Rhesus Monkeys.","26446308",42]
["1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one","1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one","C000594749","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26675680","The Phosphodiesterase 10A Selective Inhibitor TAK-063 Improves Cognitive Functions Associated with Schizophrenia in Rodent Models.","26675680",42]
["1-(2-pyrimidinyl)piperazine","1-(2-pyrimidinyl)piperazine","C037921","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9379784","Pharmacokinetics and CNS pharmacodynamics of the 5-HT1A agonist buspirone in humans following acute L-tryptophan depletion challenge.","9379784",42]
["1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine","1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine","C516975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28449891","The European Medicines Agency review of pitolisant for treatment of narcolepsy: summary of the scientific assessment by the Committee for Medicinal Products for Human Use.","28449891",42]
["1-(3-chlorophenyl)piperazine","1-(3-chlorophenyl)piperazine","C015068","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7814826","The effects of administration of mCPP on psychological, cognitive, cardiovascular, hormonal and MHPG measurements in human volunteers.","7814826",42]
["1-(3-chlorophenyl)piperazine","1-(3-chlorophenyl)piperazine","C015068","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8524975","Serotonergic modulation of anticholinergic effects on cognition and behavior in elderly humans.","8524975",42]
["1-(3-chlorophenyl)piperazine","1-(3-chlorophenyl)piperazine","C015068","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9532345","The influence of ondansetron and m-chlorophenylpiperazine on scopolamine-induced cognitive, behavioral, and physiological responses in young healthy controls.","9532345",42]
["1-(5-chloro-2-hydroxyphenyl)-3-(2-chloro-5-trifluoromethylphenyl)urea","1-(5-chloro-2-hydroxyphenyl)-3-(2-chloro-5-trifluoromethylphenyl)urea","C523981","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17625074","An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo.","17625074",42]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27791202","Fasudil, an inhibitor of Rho-associated coiled-coil kinase, improves cognitive impairments induced by smoke exposure.","27791202",42]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28534935","Effect of fasudil on cognitive function following status convulsion in rats.","28534935",42]
["1-(benzofurazan-5-ylcarbonyl)piperidine","1-(benzofurazan-5-ylcarbonyl)piperidine","C521407","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18795266","Evaluation of the pro-cognitive effects of the AMPA receptor positive modulator, 5-(1-piperidinylcarbonyl)-2,1,3-benzoxadiazole (CX691), in the rat.","18795266",42]
["1-(quinoxalin-6-ylcarbonyl)piperidine","1-(quinoxalin-6-ylcarbonyl)piperidine","C097396","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11593073","A placebo-controlled pilot study of the ampakine CX516 added to clozapine in schizophrenia.","11593073",42]
["1,3,7,9-tetramethyluric acid","1,3,7,9-tetramethyluric acid","C077059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26610558","Cognitive Performance and Mood Following Ingestion of a Theacrine-Containing Dietary Supplement, Caffeine, or Placebo by Young Men and Women.","26610558",42]
["1,3,7,9-tetramethyluric acid","1,3,7,9-tetramethyluric acid","C077059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26766930","Safety of TeaCrine®, a non-habituating, naturally-occurring purine alkaloid over eight weeks of continuous use.","26766930",42]
["1,4-dihydropyridine","1,4-dihydropyridine","C038806","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10731625","Effects of isradipine, a dihydropyridine-class calcium channel antagonist, on D-methamphetamine-induced cognitive and physiological changes in humans.","10731625",42]
["1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydroacridine","1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydroacridine","C122128","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11914957","Schisandrin B protects against tacrine- and bis(7)-tacrine-induced hepatotoxicity and enhances cognitive function in mice.","11914957",42]
["1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydroacridine","1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydroacridine","C122128","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22330749","Effect of bis(7)-tacrine on cognition in rats with chronic cerebral ischemia.","22330749",42]
["11-hydroxy-delta(9)-tetrahydrocannabinol","11-hydroxy-delta(9)-tetrahydrocannabinol","C001427","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16105257","Assessment of driving capability through the use of clinical and psychomotor tests in relation to blood cannabinoids levels following oral administration of 20 mg dronabinol or of a cannabis decoction made with 20 or 60 mg Delta9-THC.","16105257",42]
["11-hydroxy-delta(9)-tetrahydrocannabinol","11-hydroxy-delta(9)-tetrahydrocannabinol","C001427","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18695931","Delta-9-tetrahydrocannabinol (THC) serum concentrations and pharmacological effects in males after smoking a combination of tobacco and cannabis containing up to 69 mg THC.","18695931",42]
["11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid","11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid","C016780","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16105257","Assessment of driving capability through the use of clinical and psychomotor tests in relation to blood cannabinoids levels following oral administration of 20 mg dronabinol or of a cannabis decoction made with 20 or 60 mg Delta9-THC.","16105257",42]
["11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid","11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid","C016780","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18695931","Delta-9-tetrahydrocannabinol (THC) serum concentrations and pharmacological effects in males after smoking a combination of tobacco and cannabis containing up to 69 mg THC.","18695931",42]
["15,16-dihydrotanshinone I","15,16-dihydrotanshinone I","C401932","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17714702","Tanshinone congeners improve memory impairments induced by scopolamine on passive avoidance tasks in mice.","17714702",42]
["1-butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)-pyridone","1-butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)-pyridone","C000594993","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25735992","Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813, a positive allosteric modulator of mGluR2, in two randomised, double-blind phase-I studies.","25735992",42]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17603755","Treatment of Niemann-Pick disease type C in two children with miglustat: initial responses and maintenance of effects over 1 year.","17603755",42]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21658716","Evaluation of miglustat treatment in patients with type III mucopolysaccharidosis: a randomized, double-blind, placebo-controlled study.","21658716",42]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22476655","Long-term efficacy of miglustat in paediatric patients with Niemann-Pick disease type C.","22476655",42]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26400487","Chronic adjunction of 1-deoxynojirimycin protects from age-related behavioral and biochemical changes in the SAMP8 mice.","26400487",42]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27834854","Pharmacologic Treatment Assigned for Niemann Pick Type C1 Disease Partly Changes Behavioral Traits in Wild-Type Mice.","27834854",42]
["1-Deoxynojirimycin","1-Deoxynojirimycin","D017485","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"29074317","Alteration of cortical excitability and its modulation by Miglustat in Niemann-Pick disease type C.","29074317",42]
["1-hydroxy-3-amino-2-pyrrolidone","1-hydroxy-3-amino-2-pyrrolidone","C001369","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8883856","The glycine/NMDA receptor antagonist HA-966 impairs visual recognition memory in rhesus monkeys.","8883856",42]
["1-Methyl-3-isobutylxanthine","1-Methyl-3-isobutylxanthine","D015056","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1711703","Long-term effects of neonatal exposure to isobutylmethylxanthine. I. Retardation of learning with antagonism by mianserin.","1711703",42]
["1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine","1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine","C048977","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8099527","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) disrupts social memory/recognition processes in the male mouse.","8099527",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10036286","Frontal cognitive impairments and saccadic deficits in low-dose MPTP-treated monkeys.","10036286",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10727642","Effects of the partial glycine agonist D-cycloserine on cognitive functioning in chronic low dose MPTP-treated monkeys.","10727642",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12503373","[The role of substantia nigra in the cognitive activity in cats].","12503373",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18983875","Beneficial effects of pioglitazone on cognitive impairment in MPTP model of Parkinson's disease.","18983875",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19368843","Interaction between nicotinic and dopaminergic therapies on cognition in a chronic Parkinson model.","19368843",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19626386","Neuroprotective effect of PACAP on translational control alteration and cognitive decline in MPTP parkinsonian mice.","19626386",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"2002219","Chronic low-dose MPTP in nonhuman primates: a possible model for attention deficit disorder.","2002219",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2073585","Chronic exposure to low doses of MPTP. II. Neurochemical and pathological consequences in cognitively-impaired, motor asymptomatic monkeys.","2073585",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2300245","Cognitive change following MPTP exposure.","2300245",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2364263","Cognitive and motor deficits in the acquisition of an object retrieval/detour task in MPTP-treated monkeys.","2364263",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23758587","Lack of long-term changes in circadian, locomotor, and cognitive functions in acute and chronic MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse models of Parkinson's disease.","23758587",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2397401","Chronic exposure to low doses of MPTP. I. Cognitive deficits in motor asymptomatic monkeys.","2397401",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24687411","MDMA administration during adolescence exacerbates MPTP-induced cognitive impairment and neuroinflammation in the hippocampus and prefrontal cortex.","24687411",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25108180","Increased DAT binding in the early stage of the dopaminergic lesion: a longitudinal [11C]PE2I binding study in the MPTP-monkey.","25108180",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28577132","Tangeretin inhibits neurodegeneration and attenuates inflammatory responses and behavioural deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease dementia in rats.","28577132",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28986252","Uric acid demonstrates neuroprotective effect on Parkinson's disease mice through Nrf2-ARE signaling pathway.","28986252",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C67,B67)","v":"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"},"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J67,K67)","v":"Cognition"},"D003071","Cognition",0,1,1993,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q67,Q67)","v":"8099527"},"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) disrupts social memory/recognition processes in the male mouse.","8099527",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9506547","Effects of the nicotinic acetylcholine receptor agonist SIB-1508Y on object retrieval performance in MPTP-treated monkeys: comparison with levodopa treatment.","9506547",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9566501","Cognitive changes in mice following moderate MPTP exposure.","9566501",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9762718","Residual lesions of operant behavior in monkeys following recovery from MPTP-induced Parkinson-like syndrome.","9762718",42]
["1-methylpiperidine-4-spiro-(2'-methylthiazoline)","1-methylpiperidine-4-spiro-(2'-methylthiazoline)","C111926","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10462196","Facilitation of memory performance by a novel muscarinic agonist in young and old rats.","10462196",42]
["1-methylpiperidine-4-spiro-(2'-methylthiazoline)","1-methylpiperidine-4-spiro-(2'-methylthiazoline)","C111926","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12212772","AF150(S) and AF267B: M1 muscarinic agonists as innovative therapies for Alzheimer's disease.","12212772",42]
["1-methylpiperidine-4-spiro-(2'-methylthiazoline)","1-methylpiperidine-4-spiro-(2'-methylthiazoline)","C111926","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9572284","M1 muscarinic agonist treatment reverses cognitive and cholinergic impairments of apolipoprotein E-deficient mice.","9572284",42]
["1-methylpiperidine-4-spiro-(2'-methylthiazoline)","1-methylpiperidine-4-spiro-(2'-methylthiazoline)","C111926","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9789827","The effects of the acetylcholinesterase inhibitor ENA713 and the M1 agonist AF150(S) on apolipoprotein E deficient mice.","9789827",42]
["1-Naphthylamine","1-Naphthylamine","D015057","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8617708","Absence of effect of sertraline on the pharmacokinetics and pharmacodynamics of phenytoin.","8617708",42]
["1-Naphthylamine","1-Naphthylamine","D015057","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8617710","Absence of effect of sertraline on time-based sensitization of cognitive impairment with haloperidol.","8617710",42]
["1-Naphthylamine","1-Naphthylamine","D015057","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2258380","The effects of sertraline on psychomotor performance in elderly volunteers.","2258380",42]
["1-Naphthylamine","1-Naphthylamine","D015057","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"2970456","Drug profiling by computed electroencephalography and brain maps, with special consideration of sertraline and its psychometric effects.","2970456",42]
["1-Naphthylamine","1-Naphthylamine","D015057","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9494753","Selective serotonin reuptake inhibitor modulation of clozapine effects on cognition in schizophrenia.","9494753",42]
["2-((2-morpholino)ethylthio)-5-ethoxybenzimidazole","2-((2-morpholino)ethylthio)-5-ethoxybenzimidazole","C410924","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22442799","Effects of afobazole on cognitive behavior of the offspring of rats exposed to tobacco smoke during gestation period.","22442799",42]
["2-((2-morpholino)ethylthio)-5-ethoxybenzimidazole","2-((2-morpholino)ethylthio)-5-ethoxybenzimidazole","C410924","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27502535","Effect of Afobazole and Betaine on Cognitive Disorders in the Offspring of Rats with Streptozotocin-Induced Diabetes and Their Relationship with DNA Damage.","27502535",42]
["2-((3-(1,3-benzodioxol-5-yl)-3-(((6-methoxy-2-naphthyl)sulfonyl)amino)propanoyl)amino)-3-(4-((2,6-dimethylpiperidinyl)methyl)phenyl)-N-isopropyl-N-methylpropanamide","2-((3-(1,3-benzodioxol-5-yl)-3-(((6-methoxy-2-naphthyl)sulfonyl)amino)propanoyl)amino)-3-(4-((2,6-dimethylpiperidinyl)methyl)phenyl)-N-isopropyl-N-methylpropanamide","C487113","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23642031","Cognitive and cerebrovascular improvements following kinin B1 receptor blockade in Alzheimer's disease mice.","23642031",42]
["2-((4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy)methyl)quinoline","2-((4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy)methyl)quinoline","C545121","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19661377","Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia.","19661377",42]
["2-((4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy)methyl)quinoline","2-((4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy)methyl)quinoline","C545121","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26580130","The effects of PDE10 inhibition on attentional set-shifting do not depend on the activation of dopamine D1 receptors.","26580130",42]
["2-(1,3-dimethyl-1H-pyrazol-4-yl)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoline","2-(1,3-dimethyl-1H-pyrazol-4-yl)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoline","C524712","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17918921","Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists.","17918921",42]
["2-(2,7-dimethylpyrazolo(1,5-a)pyrimidin-6-yl)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoline","2-(2,7-dimethylpyrazolo(1,5-a)pyrimidin-6-yl)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoline","C524711","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17918921","Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists.","17918921",42]
["2-(3-(3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl) -8-(3,4,5-trifluorophenoxy)-5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyridin-8-yl)propan-2-ol","2-(3-(3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl) -8-(3,4,5-trifluorophenoxy)-5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyridin-8-yl)propan-2-ol","C000613083","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26707406","Single administration of a novel γ-secretase modulator ameliorates cognitive dysfunction in aged C57BL/6J mice.","26707406",42]
["2-(3-(3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl) -8-(3,4,5-trifluorophenoxy)-5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyridin-8-yl)propan-2-ol","2-(3-(3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl) -8-(3,4,5-trifluorophenoxy)-5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyridin-8-yl)propan-2-ol","C000613083","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26707977","Pharmacological properties of a novel and potent γ-secretase modulator as a therapeutic option for the treatment of Alzheimer's disease.","26707977",42]
["2-(3',4',5',6'-tetrahydro-2'H-(2,4') bipyridinyl-1'-yl)-N-m-tolyl-acetamide","2-(3',4',5',6'-tetrahydro-2'H-(2,4') bipyridinyl-1'-yl)-N-m-tolyl-acetamide","C506999","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16154186","A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats.","16154186",42]
["2-(3',4',5',6'-tetrahydro-2'H-(2,4') bipyridinyl-1'-yl)-N-m-tolyl-acetamide","2-(3',4',5',6'-tetrahydro-2'H-(2,4') bipyridinyl-1'-yl)-N-m-tolyl-acetamide","C506999","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"19020411","Selective dopamine D4 receptor agonist (A-412997) improves cognitive performance and stimulates motor activity without influencing reward-related behaviour in rat.","19020411",42]
["2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one","2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one","C539142","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25442113","Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress.","25442113",42]
["2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone","2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone","C569113","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24175493","Methoxetamine (MXE)--a phenomenological study of experiences induced by a \"legal high\" from the internet.","24175493",42]
["2-(3-trifluoromethylphenyl)histamine","2-(3-trifluoromethylphenyl)histamine","C092716","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12755399","Pro-cognitive effect of a selective histamine H1-receptor agonist, 2-(3-trifluoromethylphenyl)histamine, in the rat object recognition test.","12755399",42]
["2-(4'-(5-methylhexahydropyrrolo(3,4-b)pyrrol-1-yl)biphenyl-4-yl)-2H-pyridazin-3-one","2-(4'-(5-methylhexahydropyrrolo(3,4-b)pyrrol-1-yl)biphenyl-4-yl)-2H-pyridazin-3-one","C576396","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22815533","Pharmacological properties and procognitive effects of ABT-288, a potent and selective histamine H3 receptor antagonist.","22815533",42]
["2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate","2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate","C071738","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11728429","Beneficial effect of the sigma(1) receptor agonist PRE-084 against the spatial learning deficits in aged rats.","11728429",42]
["2-(5-methyl-2-oxo-4-phenylpyrrolidin-1-yl)acetamide","2-(5-methyl-2-oxo-4-phenylpyrrolidin-1-yl)acetamide","C000592155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24490863","The cognition-enhancing activity of E1R, a novel positive allosteric modulator of sigma-1 receptors.","24490863",42]
["2-(sec-butyl)-4,5-dihydrothiazole","2-(sec-butyl)-4,5-dihydrothiazole","C049351","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26136453","Cross-generational impact of a male  murine pheromone 2-sec-butyl-4,5-  dihydrothiazole in female mice.","26136453",42]
["2,2',4,4'-tetrabromodiphenyl ether","2,2',4,4'-tetrabromodiphenyl ether","C511295","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24870060","Prenatal polybrominated diphenyl ether exposures and neurodevelopment in U.S. children through 5 years of age: the HOME study.","24870060",42]
["2,2',4,4'-tetrabromodiphenyl ether","2,2',4,4'-tetrabromodiphenyl ether","C511295","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25229083","More evidence for PBDEs as neurotoxicants: cohort study corroborates earlier findings.","25229083",42]
["2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine","2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine","D015647","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"21901319","D₁ receptor activation improves vigilance in rats as measured by the 5-choice continuous performance test.","21901319",42]
["2',3',4',5'-tetrahydroxystilbene-2-O-beta-D-glucoside","2',3',4',5'-tetrahydroxystilbene-2-O-beta-D-glucoside","C489707","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27565551","Impact of 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucoside on cognitive deficits in animal models of Alzheimer's disease: a systematic review.","27565551",42]
["2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside","2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside","C093026","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20951128","Tetrahydroxystilbene glucoside, a plant-derived cognitive enhancer, promotes hippocampal synaptic plasticity.","20951128",42]
["2,4,5,2',4',5'-hexachlorobiphenyl","2,4,5,2',4',5'-hexachlorobiphenyl","C014024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23085522","Evaluating the neurotoxic effects of lactational exposure to persistent organic pollutants (POPs) in Spanish children.","23085522",42]
["2,4-dithiobiuret","2,4-dithiobiuret","C007540","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8833420","2,4-Dithiobiuret in rats: cognitive facilitation after acute injection precedes motor impairment after repeated daily injections.","8833420",42]
["2,5-hexanedione","2,5-hexanedione","C011269","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11869822","Early spatial memory deficit induced by 2,5-hexanedione in the rat.","11869822",42]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22398393","25-hydroxyvitamin D and physical and cognitive performance in older people with chronic conditions.","22398393",42]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24635412","Relationship between 25-hydroxyvitamin D and cognitive function in older adults: the Health, Aging and Body Composition Study.","24635412",42]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26130325","Serum 25-hydroxyvitamin D is associated with reduced verbal episodic memory in healthy, middle-aged and older adults.","26130325",42]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26470401","Vitamin D and neurocognitive disorder due to   Alzheimer's disease: A review of the literature.","26470401",42]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26585952","Vitamin D supplementation to prevent depression and poor physical function in older adults: Study protocol of the D-Vitaal study, a randomized placebo-controlled clinical trial.","26585952",42]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26901583","[Relationship between 25-hydroxy vitamin D and cognitive status in older adults: the COGNIDAGE study].","26901583",42]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"28042052","Cognitive changes under memantine according to vitamin D status in Alzheimer patients: An exposed/unexposed cohort pilot study.","28042052",42]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28167237","Does high dose vitamin D supplementation enhance cognition?: A randomized trial in healthy adults.","28167237",42]
["2-amino-3-((3,4-difluorophenyl)sulfanylmethyl)-4-hydroxy-bicyclo(3.1.0)hexane-2,6-dicarboxylic acid hydrochloride","2-amino-3-((3,4-difluorophenyl)sulfanylmethyl)-4-hydroxy-bicyclo(3.1.0)hexane-2,6-dicarboxylic acid hydrochloride","C000620392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28285123","Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects.","28285123",42]
["2-chloro-N-((S)-phenyl((2S)-piperidin-2-yl)methyl)-3-trifluoromethyl benzamide","2-chloro-N-((S)-phenyl((2S)-piperidin-2-yl)methyl)-3-trifluoromethyl benzamide","C507205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21530555","Blockade of glycine transporter 1 by SSR-504734 promotes cognitive flexibility in glycine/NMDA receptor-dependent manner.","21530555",42]
["2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione","2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione","C001886","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1506863","Comparison of the effects of selective and nonselective muscarinic agonists on cognition and thermoregulation in primates.","1506863",42]
["2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione","2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione","C001886","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2644580","Failure of cholinergic agonist RS-86 to improve cognition and movement in PSP despite effects on sleep.","2644580",42]
["2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione","2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione","C001886","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3524514","Muscarinic agonist therapy of Alzheimer's disease. A clinical trial of RS-86.","3524514",42]
["2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione","2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione","C001886","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3651528","RS 86 in the treatment of Alzheimer's disease: cognitive and biological effects.","3651528",42]
["2-ethylhexanol","2-ethylhexanol","C034017","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"16712936","From neurotoxic to chemosensory effects: new insights on acute solvent neurotoxicity exemplified by acute effects of 2-ethylhexanol.","16712936",42]
["2-fluoro-3-(2-azetidinylmethoxy)pyridine","2-fluoro-3-(2-azetidinylmethoxy)pyridine","C119803","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18949462","Galantamine-induced improvements in cognitive function are not related to alterations in alpha(4)beta (2) nicotinic receptors in early Alzheimer's disease as measured in vivo by 2-[18F]fluoro-A-85380 PET.","18949462",42]
["2-linoleoylglycerol","2-linoleoylglycerol","C114955","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28606779","2-Arachidonoylglycerol as a possible treatment for anorexia nervosa in animal model in mice.","28606779",42]
["2-palmitoylglycerol","2-palmitoylglycerol","C114956","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28606779","2-Arachidonoylglycerol as a possible treatment for anorexia nervosa in animal model in mice.","28606779",42]
["2-tert-butylhydroquinone","2-tert-butylhydroquinone","C018855","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24848277","Tert-butylhydroquinone alleviates early brain injury and cognitive dysfunction after experimental subarachnoid hemorrhage: role of Keap1/Nrf2/ARE pathway.","24848277",42]
["3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo(2,3-b)pyridine","3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo(2,3-b)pyridine","C099630","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18835699","Dopamine D4 receptor antagonist L745,870 abolishes cognitive effects of intracerebroventricular angiotensin IV and des-Phe(6)-Ang IV in rats.","18835699",42]
["3-((cyclohexylmethyl)(3,3-dimethylbutyl)amino)-2-(4-(trifluoromethyl)phenyl)cyclohexyl)acetic acid","3-((cyclohexylmethyl)(3,3-dimethylbutyl)amino)-2-(4-(trifluoromethyl)phenyl)cyclohexyl)acetic acid","C000593233","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24373902","Pharmacological characterization of the novel γ-secretase modulator AS2715348, a potential therapy for Alzheimer's disease, in rodents and nonhuman primates.","24373902",42]
["3-((methylsulfonyl)amino)-2-phenyl-N-(1-phenylpropyl)quinolin-4-carboxamide","3-((methylsulfonyl)amino)-2-phenyl-N-(1-phenylpropyl)quinolin-4-carboxamide","C555357","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24525659","The selective neurokinin 3 antagonist AZD2624 does not improve symptoms or cognition in schizophrenia: a proof-of-principle study.","24525659",42]
["3-(1-(2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl)-3,6-dihydro-2H-pyridin-4-yl)-6-chloro-1H-indole","3-(1-(2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl)-3,6-dihydro-2H-pyridin-4-yl)-6-chloro-1H-indole","C527164","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17689529","Lu 35-138 ((+)-(S)-3-{1-[2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl]-3,6-dihydro-2H-pyridin-4-yl}-6-chloro-1H-indole), a dopamine D4 receptor antagonist and serotonin reuptake inhibitor: characterisation of its in vitro profile and pre-clinical antipsychotic potential.","17689529",42]
["3-(2,2,2-trimethylhydrazine)propionate","3-(2,2,2-trimethylhydrazine)propionate","C050147","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24908956","[Parallel pharmacological correction of myocardial dysfunction, cognitive and psychopathological disordres in patients with congestive heart failure].","24908956",42]
["3-(2,4-dimethoxybenzylidene)anabaseine","3-(2,4-dimethoxybenzylidene)anabaseine","C088936","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12629535","Safety, pharmacokinetics, and effects on cognitive function of multiple doses of GTS-21 in healthy, male volunteers.","12629535",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C131,B131)","v":"3-(2,4-dimethoxybenzylidene)anabaseine"},"3-(2,4-dimethoxybenzylidene)anabaseine","C088936","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J131,K131)","v":"Cognition"},"D003071","Cognition",0,1,2013,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q131,Q131)","v":"22659472"},"The nicotinic α7 receptor agonist GTS-21 improves cognitive performance in ketamine impaired rhesus monkeys.","22659472",42]
["3-(2,4-dimethoxybenzylidene)anabaseine","3-(2,4-dimethoxybenzylidene)anabaseine","C088936","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24111888","α7-nicotinic acetylcholine receptor agonists for cognitive enhancement in schizophrenia.","24111888",42]
["3-(2,4-dimethoxybenzylidene)anabaseine","3-(2,4-dimethoxybenzylidene)anabaseine","C088936","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24595504","Effects of the nicotinic α7 receptor partial agonist GTS-21 on NMDA-glutamatergic receptor related deficits in sensorimotor gating and recognition memory in rats.","24595504",42]
["3-(2,4-dimethoxybenzylidene)anabaseine","3-(2,4-dimethoxybenzylidene)anabaseine","C088936","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7796104","Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21.","7796104",42]
["3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol","3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol","C054649","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25443717","CP55,940 attenuates spatial memory retrieval in mice.","25443717",42]
["3-(3-(3-florophenyl-2-propyn-1-ylthio)-1,2,5-thiadiazol-4-yl)-1,2,5,6- tetrahydro-1-methylpyridine oxalate","3-(3-(3-florophenyl-2-propyn-1-ylthio)-1,2,5-thiadiazol-4-yl)-1,2,5,6- tetrahydro-1-methylpyridine oxalate","C533736","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20178835","A novel derivative of xanomeline improves fear cognition in aged mice.","20178835",42]
["3-(3-(pyridine-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile","3-(3-(pyridine-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile","C561896","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22506660","Augmentation of cognitive function by NS9283, a stoichiometry-dependent positive allosteric modulator of α2- and α4-containing nicotinic acetylcholine receptors.","22506660",42]
["3'-(3-methylbenzo(b)thiophen-5-yl)spiro(1-azabicyclo(2.2.2)octane-3,5'-oxazolidin)-2'-one","3'-(3-methylbenzo(b)thiophen-5-yl)spiro(1-azabicyclo(2.2.2)octane-3,5'-oxazolidin)-2'-one","C513160","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16821797","(R)-3'-(3-methylbenzo[b]thiophen-5-yl)spiro[1-azabicyclo[2,2,2]octane-3,5'-oxazolidin]-2'-one, a novel and potent alpha7 nicotinic acetylcholine receptor partial agonist displays cognitive enhancing properties.","16821797",42]
["3-(4-hydroxy-3-(3-oxo-but-1-enyl)-phenyl)-acrylic acid","3-(4-hydroxy-3-(3-oxo-but-1-enyl)-phenyl)-acrylic acid","C110594","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20376430","Cognitive improvement during continuous sedation in critically ill, awake and responsive patients: the Acute Neurological ICU Sedation Trial (ANIST).","20376430",42]
["3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide","3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide","C500530","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23216087","Pharmacological blockade of TRPV1 receptors modulates the effects of 6-OHDA on motor and cognitive functions in a rat model of Parkinson's disease.","23216087",42]
["3-(5-chloro-2-furoyl)-3,7-diazabicyclo(3.3.0)octane","3-(5-chloro-2-furoyl)-3,7-diazabicyclo(3.3.0)octane","C578484","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"23640072","A randomized, double-blind, placebo-controlled crossover study of α4β 2* nicotinic acetylcholine receptor agonist AZD1446 (TC-6683) in adults with attention-deficit/hyperactivity disorder.","23640072",42]
["3,3'-iminodipropionitrile","3,3'-iminodipropionitrile","C008110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25817367","Ameliorative effect of gastrodin on 3,3'-iminodipropionitrile-induced memory impairment in rats.","25817367",42]
["3,4-diaminopyridine","3,4-diaminopyridine","C016361","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7751839","3,4-diaminopyridine as a treatment for amyotrophic lateral sclerosis.","7751839",42]
["3,4-Dihydroxyphenylacetic Acid","3,4-Dihydroxyphenylacetic Acid","D015102","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10800755","In vivo effects of the putative cognitive enhancer KA-672.HCl in comparison with 8-hydroxy-2-(di-N-propylamino) tetralin and haloperidol on dopamine, 3,4-dihydroxyphenylacetic acid, serotonin and 5-hydroxyindoleacetic acid levels in striatal and cortical brain regions.","10800755",42]
["3,4-dihydroxyphenylethanol","3,4-dihydroxyphenylethanol","C005975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27287957","Hydroxytyrosol mildly improve cognitive function independent of APP processing in APP/PS1 mice.","27287957",42]
["3,4-Methylenedioxyamphetamine","3,4-Methylenedioxyamphetamine","D015104","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10327426","Neurometabolic effects of psilocybin, 3,4-methylenedioxyethylamphetamine (MDE) and d-methamphetamine in healthy volunteers. A double-blind, placebo-controlled PET study with [18F]FDG.","10327426",42]
["3,4-Methylenedioxyamphetamine","3,4-Methylenedioxyamphetamine","D015104","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11489463","Enantio-selective cognitive and brain activation effects of N-ethyl-3,4-methylenedioxyamphetamine in humans.","11489463",42]
["3,4-methylenedioxyethamphetamine","3,4-methylenedioxyethamphetamine","C051800","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10327426","Neurometabolic effects of psilocybin, 3,4-methylenedioxyethylamphetamine (MDE) and d-methamphetamine in healthy volunteers. A double-blind, placebo-controlled PET study with [18F]FDG.","10327426",42]
["3,4-methylenedioxyethamphetamine","3,4-methylenedioxyethamphetamine","C051800","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11489463","Enantio-selective cognitive and brain activation effects of N-ethyl-3,4-methylenedioxyamphetamine in humans.","11489463",42]
["3-alpha-tropyl-2-(phenylthio)butyrate","3-alpha-tropyl-2-(phenylthio)butyrate","C106486","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"9025257","Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent.","9025257",42]
["3-benzenesulfonyl-8-piperazin-1-ylquinoline","3-benzenesulfonyl-8-piperazin-1-ylquinoline","C548140","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20872778","SB-742457 and donepezil in Alzheimer disease: a randomized, placebo-controlled study.","20872778",42]
["3-benzenesulfonyl-8-piperazin-1-ylquinoline","3-benzenesulfonyl-8-piperazin-1-ylquinoline","C548140","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22766392","Age-related declines in delayed non-match-to-sample performance (DNMS) are reversed by the novel 5HT6 receptor antagonist SB742457.","22766392",42]
["3-bromo-10-difluoromethyl-9H-imidazo(1,5-a)(1,2,4)triazolo(1,5-d)(1,4)benzodiazepine","3-bromo-10-difluoromethyl-9H-imidazo(1,5-a)(1,2,4)triazolo(1,5-d)(1,4)benzodiazepine","C542509","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18936916","RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors.","18936916",42]
["3-chloro-4-fluorophenyl-(4-fluoro-4-(((5-methyl-6-methylaminopyridin-2-ylmethyl)amino)methyl)piperidin-1-yl)methanone","3-chloro-4-fluorophenyl-(4-fluoro-4-(((5-methyl-6-methylaminopyridin-2-ylmethyl)amino)methyl)piperidin-1-yl)methanone","C119079","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20488670","F15599, a preferential post-synaptic 5-HT1A receptor agonist: activity in models of cognition in comparison with reference 5-HT1A receptor agonists.","20488670",42]
["3-chloro-4-fluorophenyl-(4-fluoro-4-(((5-methylpyrimidin-2-ylmethyl)amino)methyl)piperidin-1-yl)methanone","3-chloro-4-fluorophenyl-(4-fluoro-4-(((5-methylpyrimidin-2-ylmethyl)amino)methyl)piperidin-1-yl)methanone","C524188","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20488670","F15599, a preferential post-synaptic 5-HT1A receptor agonist: activity in models of cognition in comparison with reference 5-HT1A receptor agonists.","20488670",42]
["3-fluoro4-(4-((2-(3,5-dimethylphenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide","3-fluoro4-(4-((2-(3,5-dimethylphenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide","C000590915","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24619932","Safety, tolerability, and pharmacokinetic evaluation of single- and multiple-ascending doses of a novel kappa opioid receptor antagonist LY2456302 and drug interaction with ethanol in healthy subjects.","24619932",42]
["3-furan-2-yl-N-p-tolylacrylamide","3-furan-2-yl-N-p-tolylacrylamide","C000593312","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26276349","Pro-cognitive activity in rats of 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor.","26276349",42]
["3-furan-2-yl-N-p-tolylacrylamide","3-furan-2-yl-N-p-tolylacrylamide","C000593312","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27717880","3-Furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic receptor, reverses schizophrenia-like cognitive and social deficits in rats.","27717880",42]
["3-Hydroxybutyric Acid","3-Hydroxybutyric Acid","D020155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15123336","Effects of beta-hydroxybutyrate on cognition in memory-impaired adults.","15123336",42]
["3-Hydroxybutyric Acid","3-Hydroxybutyric Acid","D020155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19223595","Medium-chain fatty acids improve cognitive function in intensively treated type 1 diabetic patients and support in vitro synaptic transmission during acute hypoglycemia.","19223595",42]
["3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","C088383","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10229057","Acute effects of the selective cholinergic channel activator (nicotinic agonist) ABT-418 in Alzheimer's disease.","10229057",42]
["3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","C088383","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17689498","Neuronal nicotinic receptor agonists for the treatment of attention-deficit/hyperactivity disorder: focus on cognition.","17689498",42]
["3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","C088383","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7518514","(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization.","7518514",42]
["3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","C088383","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7913497","(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization.","7913497",42]
["3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","C088383","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8534424","Potential treatment of Alzheimer disease using cholinergic channel activators (ChCAs) with cognitive enhancement, anxiolytic-like, and cytoprotective properties.","8534424",42]
["3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole","C088383","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9022806","Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.","9022806",42]
["3-n-butylphthalide","3-n-butylphthalide","C027125","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24512016","Improvement of cognitive deficits in SAMP8 mice by 3-n-butylphthalide.","24512016",42]
["3-n-butylphthalide","3-n-butylphthalide","C027125","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25149651","Effects of L-3-n-butylphthalide on cognitive dysfunction and NR2B expression in hippocampus of streptozotocin (STZ)-induced diabetic rats.","25149651",42]
["3-n-butylphthalide","3-n-butylphthalide","C027125","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26215907","L-3-n-butylphthalide Promotes Neurogenesis and Neuroplasticity in Cerebral Ischemic Rats.","26215907",42]
["3-n-butylphthalide","3-n-butylphthalide","C027125","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26827641","Dl-3-n-butylphthalide-induced upregulation of antioxidant defense is involved in the enhancement of cross talk between CREB and Nrf2 in an Alzheimer's disease mouse model.","26827641",42]
["3-n-butylphthalide","3-n-butylphthalide","C027125","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28145815","Dl-3-n-butylphthalide can improve the cognitive function of patients with acute ischemic stroke: a prospective intervention study.","28145815",42]
["3-n-butylphthalide","3-n-butylphthalide","C027125","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28990110","Effects of butylphthalide on cognitive decline in diabetic rats.","28990110",42]
["3-nitropropionic acid","3-nitropropionic acid","C015392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11681849","Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid.","11681849",42]
["3-nitropropionic acid","3-nitropropionic acid","C015392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8622131","Chronic 3-nitropropionic acid treatment in baboons replicates the cognitive and motor deficits of Huntington's disease.","8622131",42]
["3-nitropropionic acid","3-nitropropionic acid","C015392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22327485","N-Acetylcysteine reverses mitochondrial dysfunctions and behavioral abnormalities in 3-nitropropionic acid-induced Huntington's disease.","22327485",42]
["3-nitropropionic acid","3-nitropropionic acid","C015392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28164735","Ameliorating effect of Celastrus paniculatus standardized extract and its fractions on 3-nitropropionic acid induced neuronal damage in rats: possible antioxidant mechanism.","28164735",42]
["4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride","4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride","C119207","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11561092","SIB-1553A, (+/-)-4-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride, a subtype-selective ligand for nicotinic acetylcholine receptors with putative cognitive-enhancing properties: effects on working and reference memory performances in aged rodents and nonhuman primates.","11561092",42]
["4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride","4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride","C119207","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12700710","Cognitive enhancing properties and tolerability of cholinergic agents in mice: a comparative study of nicotine, donepezil, and SIB-1553A, a subtype-selective ligand for nicotinic acetylcholine receptors.","12700710",42]
["4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride","4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride","C119207","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12885429","In vitro pharmacological characterization of (+/-)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a nicotinic acetylcholine receptor ligand.","12885429",42]
["4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride","4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride","C119207","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19368843","Interaction between nicotinic and dopaminergic therapies on cognition in a chronic Parkinson model.","19368843",42]
["4-((3-(1,6-dihyro-6-oxo-9H-purin-9-yl)-1-oxopropyl)amino)benzoic acid","4-((3-(1,6-dihyro-6-oxo-9H-purin-9-yl)-1-oxopropyl)amino)benzoic acid","C086241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12231461","Brain metabolic effects of Neotrofin in patients with Alzheimer's disease.","12231461",42]
["4-((3-(1,6-dihyro-6-oxo-9H-purin-9-yl)-1-oxopropyl)amino)benzoic acid","4-((3-(1,6-dihyro-6-oxo-9H-purin-9-yl)-1-oxopropyl)amino)benzoic acid","C086241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8126346","The interaction of ethanol with the cognitive enhancers tacrine, physostigmine, and AIT-082.","8126346",42]
["4-((4-(((4-amino-2,3,5,6-tetramethylanilino)acetyl)(methyl)amino)-1-piperidinyl)methyl)benzamide","4-((4-(((4-amino-2,3,5,6-tetramethylanilino)acetyl)(methyl)amino)-1-piperidinyl)methyl)benzamide","C584014","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25130662","SUN11602 has basic fibroblast growth factor-like activity and attenuates neuronal damage and cognitive deficits in a rat model of Alzheimer's disease induced by amyloid β and excitatory amino acids.","25130662",42]
["4-(3-(4-butylpiperidin-1-yl)propyl)-7-fluoro-4H-benzo(1,4)oxazin-3-one","4-(3-(4-butylpiperidin-1-yl)propyl)-7-fluoro-4H-benzo(1,4)oxazin-3-one","C516553","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18513127","Antipsychotic-like behavioral effects and cognitive enhancement by a potent and selective muscarinic M-sub-1 receptor agonist, AC-260584.","18513127",42]
["4-(3-(4-butylpiperidin-1-yl)propyl)-7-fluoro-4H-benzo(1,4)oxazin-3-one","4-(3-(4-butylpiperidin-1-yl)propyl)-7-fluoro-4H-benzo(1,4)oxazin-3-one","C516553","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19835892","AC-260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model.","19835892",42]
["4-(3-(4-piperidin-1-ylbut-1-ynyl)benzyl)morpholine","4-(3-(4-piperidin-1-ylbut-1-ynyl)benzyl)morpholine","C515396","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19345233","JNJ-10181457, a selective non-imidazole histamine H(3) receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition.","19345233",42]
["4',7-dihydroxy-3,4-dihydroisoflavone","4',7-dihydroxy-3,4-dihydroisoflavone","C007610","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19054783","A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and women.","19054783",42]
["4-aminopiperidine","4-aminopiperidine","C481395","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12824022","4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs.","12824022",42]
["4-Aminopyridine","4-Aminopyridine","D015761","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11795455","Fatigue in progressive multiple sclerosis: results of a randomized, double-blind, placebo-controlled, crossover trial of oral 4-aminopyridine.","11795455",42]
["4-Aminopyridine","4-Aminopyridine","D015761","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23562059","Design, synthesis and evaluation of some new 4-aminopyridine derivatives in learning and memory.","23562059",42]
["4-Aminopyridine","4-Aminopyridine","D015761","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27237758","Distribution-based estimates of minimum clinically important difference in cognition, arm function and lower body function after slow release-fampridine treatment of patients with multiple sclerosis.","27237758",42]
["4-Aminopyridine","4-Aminopyridine","D015761","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27919481","Effect of slow release-Fampridine on muscle strength, rate of force development, functional capacity and cognitive function in an enriched population of MS patients. A randomized, double blind, placebo controlled study.","27919481",42]
["4-Aminopyridine","4-Aminopyridine","D015761","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7751839","3,4-diaminopyridine as a treatment for amyotrophic lateral sclerosis.","7751839",42]
["4-Butyrolactone","4-Butyrolactone","D015107","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23022689","Ligustilide alleviates brain damage and improves cognitive function in rats of chronic cerebral hypoperfusion.","23022689",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C195,B195)","v":"4'-chlorodiazepam"},"4'-chlorodiazepam","C028513","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J195,K195)","v":"Cognition"},"D003071","Cognition",0,1,2013,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q195,Q195)","v":"23128021"},"Effect of phosphamidon on cognition and oxidative stress and its modulation by ascorbic acid and 4'-chlorodiazepam in rats.","23128021",42]
["4-ethyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide","4-ethyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide","C531043","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17552506","Design, synthesis, and pharmacology of novel 7-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors.","17552506",42]
["4-hydroxybutyric acid","4-hydroxybutyric acid","C111420","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19762202","[Gamma-hydroxybutyric acid (GHB): more than a date rape drug, a potentially addictive drug].","19762202",42]
["4-hydroxybutyric acid","4-hydroxybutyric acid","C111420","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23250641","[Cognitive impairment due to intensive use and overdoses of gammahydroxybutyric acid (GHB)].","23250641",42]
["4-phenylpiracetam","4-phenylpiracetam","C037917","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25898541","[Role of functional state of neuronal mitochondria of cerebral cortex in mechanisms of nootropic activity of neuroprotectors in rats with alloxan hyperglycemia].","25898541",42]
["5-(2-azetidinylmethoxy)-2-chloropyridine","5-(2-azetidinylmethoxy)-2-chloropyridine","C109763","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17706609","Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys.","17706609",42]
["5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine","5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine","C571284","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22135384","The selective M1 muscarinic cholinergic agonist CDD-0102A enhances working memory and cognitive flexibility.","22135384",42]
["5-(4-(4-chlorophenyl)piperazin-1-ylmethyl)-1H-indole","5-(4-(4-chlorophenyl)piperazin-1-ylmethyl)-1H-indole","C527165","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17689529","Lu 35-138 ((+)-(S)-3-{1-[2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl]-3,6-dihydro-2H-pyridin-4-yl}-6-chloro-1H-indole), a dopamine D4 receptor antagonist and serotonin reuptake inhibitor: characterisation of its in vitro profile and pre-clinical antipsychotic potential.","17689529",42]
["5-(4-acetyl(1,4)diazepan-1-yl)pentanoic acid (5-(4-methoxyphenyl)-1H-pyrazol-3-yl) amide","5-(4-acetyl(1,4)diazepan-1-yl)pentanoic acid (5-(4-methoxyphenyl)-1H-pyrazol-3-yl) amide","C574768","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22468936","Discovery of a novel alpha-7 nicotinic acetylcholine receptor agonist series and characterization of the potent, selective, and orally efficacious agonist 5-(4-acetyl[1,4]diazepan-1-yl)pentanoic acid [5-(4-methoxyphenyl)-1H-pyrazol-3-yl] amide (SEN15924, WAY-361789).","22468936",42]
["5-(6-(1-azabicyclo(2,2,2)oct-3-yloxy)pyridazin-3-yl)-1H-indole","5-(6-(1-azabicyclo(2,2,2)oct-3-yloxy)pyridazin-3-yl)-1H-indole","C552256","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25426579","ABT-089, but not ABT-107, ameliorates nicotine withdrawal-induced cognitive deficits in C57BL6/J mice.","25426579",42]
["5-(8-amino-7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-3-(1-(2-phenylethyl)-4-piperidinyl)-1,3,4-oxadiazol-2(3H)-one","5-(8-amino-7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-3-(1-(2-phenylethyl)-4-piperidinyl)-1,3,4-oxadiazol-2(3H)-one","C464499","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12130738","SL65.0155, a novel 5-hydroxytryptamine(4) receptor partial agonist with potent cognition-enhancing properties.","12130738",42]
["5-(8-amino-7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-3-(1-(2-phenylethyl)-4-piperidinyl)-1,3,4-oxadiazol-2(3H)-one","5-(8-amino-7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-3-(1-(2-phenylethyl)-4-piperidinyl)-1,3,4-oxadiazol-2(3H)-one","C464499","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17011531","Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia.","17011531",42]
["5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline","5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline","C517687","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26401560","The Multi-Target Drug M30 Shows Pro-Cognitive and Anti-Inflammatory Effects in a Rat Model of Alzheimer's Disease.","26401560",42]
["5,7-Dihydroxytryptamine","5,7-Dihydroxytryptamine","D015116","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19447281","5,7-dihydroxytryptamine injections into the prefrontal cortex and nucleus accumbens differently affect prepulse inhibition and baseline startle magnitude in rats.","19447281",42]
["5-chloro-N-(2,2-dimethyl-3-(4-sulfamoylphenyl)cyclopropyl)-2-methoxybenzamide","5-chloro-N-(2,2-dimethyl-3-(4-sulfamoylphenyl)cyclopropyl)-2-methoxybenzamide","C000590932","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24917542","Characterization of RO5126946, a Novel α7 nicotinic acetylcholine receptor-positive allosteric modulator.","24917542",42]
["5-fluoro-8-(4-(4-(6-methoxyquinolin-8-yl)piperazin-1-yl)piperidin-1-yl)quinoline","5-fluoro-8-(4-(4-(6-methoxyquinolin-8-yl)piperazin-1-yl)piperidin-1-yl)quinoline","C550157","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20443629","The synthesis and biological evaluation of quinolyl-piperazinyl piperidines as potent serotonin 5-HT1A antagonists.","20443629",42]
["5-methoxy-N,N-diisopropyltryptamine","5-methoxy-N,N-diisopropyltryptamine","C033696","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16933659","An examination of the effects of 5-Methoxy-n, n-di(ISO)propyltryptamine hydrochloride (Foxy) on cognitive development in rats.","16933659",42]
["5-Methoxytryptamine","5-Methoxytryptamine","D008735","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16933659","An examination of the effects of 5-Methoxy-n, n-di(ISO)propyltryptamine hydrochloride (Foxy) on cognitive development in rats.","16933659",42]
["5-methyltetrahydrofolate","5-methyltetrahydrofolate","C005984","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8257478","Oral 5'-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study.","8257478",42]
["5-morpholin-4-ylpentanoic acid (4-pyridin-3-ylphenyl)amide","5-morpholin-4-ylpentanoic acid (4-pyridin-3-ylphenyl)amide","C540749","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19223665","Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders.","19223665",42]
["5-morpholin-4-ylpentanoic acid (4-pyridin-3-ylphenyl)amide","5-morpholin-4-ylpentanoic acid (4-pyridin-3-ylphenyl)amide","C540749","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19515567","SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist.","19515567",42]
["5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid","5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid","C499823","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25585137","Resolvins AT-D1 and E1 differentially impact functional outcome, post-traumatic sleep, and microglial activation following diffuse brain injury in the mouse.","25585137",42]
["6-((3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy)-N-methyl-3-pyridinecarboxamide","6-((3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy)-N-methyl-3-pyridinecarboxamide","C521312","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19815811","Regional differential effects of the novel histamine H3 receptor antagonist 6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on histamine release in the central nervous system of freely moving rats.","19815811",42]
["6-((3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy)-N-methyl-3-pyridinecarboxamide","6-((3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy)-N-methyl-3-pyridinecarboxamide","C521312","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28971617","Possible use of a H3R antagonist for the management of nonmotor symptoms in the Q175 mouse model of Huntington's disease.","28971617",42]
["6-(2-isopropylaminopropyl)-3-pyridinol","6-(2-isopropylaminopropyl)-3-pyridinol","C075505","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8410411","Effect of a new nootropic agent, CGS 5649B, on cognition, function, and behavior in dementia.","8410411",42]
["6-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)-2H-pyridazin-3-one","6-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)-2H-pyridazin-3-one","C561238","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22001260","CEP-26401 (irdabisant), a potent and selective histamine H₃ receptor antagonist/inverse agonist with cognition-enhancing and wake-promoting activities.","22001260",42]
["6-(4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one","6-(4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one","C572323","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21619887","The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents.","21619887",42]
["6,6-dimethyl-3-(2-hydroxyethyl)thio-1-(thiazol-2-yl)-6,7-dihydro-2-benzothiophen-4(5H)-one","6,6-dimethyl-3-(2-hydroxyethyl)thio-1-(thiazol-2-yl)-6,7-dihydro-2-benzothiophen-4(5H)-one","C452421","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12747794","Identification of a novel, selective GABA(A) alpha5 receptor inverse agonist which enhances cognition.","12747794",42]
["6,7-dihydro-4-hydroxy-7-isopropyl-6-oxo-N-(3-(piperidin-1-yl)propyl)thieno(2,3-b)pyridine-5-carboxamide","6,7-dihydro-4-hydroxy-7-isopropyl-6-oxo-N-(3-(piperidin-1-yl)propyl)thieno(2,3-b)pyridine-5-carboxamide","C525011","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17692343","VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux.","17692343",42]
["6,7-dihydroxyflavone","6,7-dihydroxyflavone","C485383","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28541476","7,8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway.","28541476",42]
["6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide","6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide","C550547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25223731","An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington's disease.","25223731",42]
["6-chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indoline","6-chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indoline","C107820","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24204954","Dissociable effects of 5-HT2C receptor antagonism and genetic inactivation on perseverance and learned non-reward in an egocentric spatial reversal task.","24204954",42]
["6-Cyano-7-nitroquinoxaline-2,3-dione","6-Cyano-7-nitroquinoxaline-2,3-dione","D018750","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27426469","Immediate and delayed treatment with gabapentin, carbamazepine and CNQX have almost similar impact on cognitive functions and behavior in the lithium-pilocarpine model in rats.","27426469",42]
["6-fluoro-9-methyl-2-phenyl-4-(pyrrolidin-1-yl-carbonyl)-2,9-dihydro-1H-pyrido(3,4-b)indol-1-one","6-fluoro-9-methyl-2-phenyl-4-(pyrrolidin-1-yl-carbonyl)-2,9-dihydro-1H-pyrido(3,4-b)indol-1-one","C432169","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18635696","The pharmacokinetic and pharmacodynamic effects of SL65.1498, a GABA-A alpha2,3 selective agonist, in comparison with lorazepam in healthy volunteers.","18635696",42]
["6-methyl-2-(phenylethynyl)pyridine","6-methyl-2-(phenylethynyl)pyridine","C121465","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15739074","The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison.","15739074",42]
["7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo(4,3-b)pyridazine","7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo(4,3-b)pyridazine","C507018","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17092968","Pharmacodynamic and pharmacokinetic effects of TPA023, a GABA(A) alpha(2,3) subtype-selective agonist, compared to lorazepam and placebo in healthy volunteers.","17092968",42]
["7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo(4,3-b)pyridazine","7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo(4,3-b)pyridazine","C507018","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18482097","GABA(A) receptor subtype-selective efficacy: TPA023, an alpha2/alpha3 selective non-sedating anxiolytic and alpha5IA, an alpha5 selective cognition enhancer.","18482097",42]
["7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo(4,3-b)pyridazine","7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo(4,3-b)pyridazine","C507018","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21145041","A randomized clinical trial of MK-0777 for the treatment of cognitive impairments in people with schizophrenia.","21145041",42]
["7-chloro-N-quinuclidin-3-yl-benzo(b)thiophene-2-carboxamide","7-chloro-N-quinuclidin-3-yl-benzo(b)thiophene-2-carboxamide","C573817","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25438724","Pharmacodynamics, pharmacokinetics, safety, and tolerability of encenicline, a selective α7 nicotinic receptor partial agonist, in single ascending-dose and bioavailability studies.","25438724",42]
["7-fluoro-N-quinuclidin-3-yl)benzo(b)thiophene-2-carboxamide","7-fluoro-N-quinuclidin-3-yl)benzo(b)thiophene-2-carboxamide","C000604696","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27866776","Activation of α7 nicotinic acetylcholine receptors facilitates long-term potentiation at the hippocampal-prefrontal cortex synapses in vivo.","27866776",42]
["7-hydroxy-2-N,N-dipropylaminotetralin","7-hydroxy-2-N,N-dipropylaminotetralin","C031349","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10371648","The dopamine D3/D2 receptor agonist 7-OH-DPAT induces cognitive impairment in the marmoset.","10371648",42]
["8,12-iso-isoprostane F2alpha-VI","8,12-iso-isoprostane F2alpha-VI","C115626","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11768373","Dietary antioxidants and dementia.","11768373",42]
["8-aminoquinoline","8-aminoquinoline","C080436","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22927947","Copper chelator induced efficient episodic memory recovery in a non-transgenic Alzheimer's mouse model.","22927947",42]
["8-cyclopentyl-1,3-dimethylxanthine","8-cyclopentyl-1,3-dimethylxanthine","C053907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1630626","Hypoxia produces cell death in the rat hippocampus in the presence of an A1 adenosine receptor antagonist: an anatomical and behavioral study.","1630626",42]
["8-Hydroxy-2-(di-n-propylamino)tetralin","8-Hydroxy-2-(di-n-propylamino)tetralin","D017371","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10800755","In vivo effects of the putative cognitive enhancer KA-672.HCl in comparison with 8-hydroxy-2-(di-N-propylamino) tetralin and haloperidol on dopamine, 3,4-dihydroxyphenylacetic acid, serotonin and 5-hydroxyindoleacetic acid levels in striatal and cortical brain regions.","10800755",42]
["8-Hydroxy-2-(di-n-propylamino)tetralin","8-Hydroxy-2-(di-n-propylamino)tetralin","D017371","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20042318","(+)-UH 232, a partial agonist of the D3 dopamine receptors, attenuates cognitive effects of angiotensin IV and des-Phe(6)-angiotensin IV in rats.","20042318",42]
["8-Hydroxy-2-(di-n-propylamino)tetralin","8-Hydroxy-2-(di-n-propylamino)tetralin","D017371","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8748396","Dissociation between cognitive and motor/motivational deficits in the delayed matching to position test: effects of scopolamine, 8-OH-DPAT and EAA antagonists.","8748396",42]
["9-methyl-beta-carboline","9-methyl-beta-carboline","C529608","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22380576","9-Methyl-β-carboline-induced cognitive enhancement is associated with elevated hippocampal dopamine levels and dendritic and synaptic proliferation.","22380576",42]
["A 77636","A 77636","C079415","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19154630","The effect of a full agonist/antagonist of the D1 receptor on locomotor activity, sensorimotor gating and cognitive function in dizocilpine-treated rats.","19154630",42]
["A349821","A349821","C489829","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19413577","Use of the H3 receptor antagonist radioligand [3H]-A-349821 to reveal in vivo receptor occupancy of cognition enhancing H3 receptor antagonists.","19413577",42]
["A-582941","A-582941","C524029","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17706609","Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys.","17706609",42]
["A-582941","A-582941","C524029","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18482100","Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties.","18482100",42]
["A-705253","A-705253","C500488","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18701765","Inhibition of Calpain Prevents N-Methyl-D-aspartate-Induced Degeneration of the Nucleus Basalis and Associated Behavioral Dysfunction.","18701765",42]
["A-705253","A-705253","C500488","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22688056","Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice.","22688056",42]
["A-705253","A-705253","C500488","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22733009","Calpain inhibition as a potential treatment of Alzheimer's disease.","22733009",42]
["A-841720","A-841720","C516995","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17016515","Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist.","17016515",42]
["A-841720","A-841720","C516995","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17551319","Comparison of the mGluR1 antagonist A-841720 in rat models of pain and cognition.","17551319",42]
["abecarnil","abecarnil","C062769","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9201796","Psychomotor effects of the anxiolytic abecarnil: a comparison with lorazepam.","9201796",42]
["ABIO 0801","ABIO 0801","C529993","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18181252","Double-blind, placebo-controlled, multiple-ascending-dose study on the effects of ABIO-08/01, a novel anxiolytic drug, on perception and cognition, utilizing event-related potential mapping and low-resolution brain electromagnetic tomography.","18181252",42]
["acamprosate","acamprosate","C043877","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12377396","A pharmacokinetic and pharmacodynamic drug interaction study of acamprosate and naltrexone.","12377396",42]
["acamprosate","acamprosate","C043877","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20021295","The neurobiology, clinical efficacy and safety of acamprosate in the treatment of alcohol dependence.","20021295",42]
["acamprosate","acamprosate","C043877","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21716064","Effects of acamprosate on cognition in a treatment study of patients with schizophrenia spectrum disorders and comorbid alcohol dependence.","21716064",42]
["Acetaminophen","Acetaminophen","D000082","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27980393","Paracetamol sharpens reflection and spatial memory: a double-blind randomized controlled study in healthy volunteers.","27980393",42]
["Acetazolamide","Acetazolamide","D000086","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19689182","Taste disturbances related to medication use.","19689182",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C259,B259)","v":"Acetazolamide"},"Acetazolamide","D000086","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J259,K259)","v":"Cognition"},"D003071","Cognition",0,1,1984,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q259,Q259)","v":"6466255"},"Cognitive impairment of acute mountain sickness and acetazolamide.","6466255",42]
["acetosulfame","acetosulfame","C006362","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23950916","Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice.","23950916",42]
["acetovanillone","acetovanillone","C056165","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20560881","Pitavastatin and 4'-hydroxy-3'-methoxyacetophenone (HMAP) reduce cognitive dysfunction in vascular dementia during experimental diabetes.","20560881",42]
["acetyl chloride","acetyl chloride","C081124","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18817812","Aluminium-induced electrophysiological, biochemical and cognitive modifications in the hippocampus of aging rats.","18817812",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11592123","Enhancement of learning capacity and cholinergic synaptic function by carnitine in aging rats.","11592123",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12598816","Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease.","12598816",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16621446","The effect of acetyl-L-carnitine administration on persons with Down syndrome.","16621446",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17658628","Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue.","17658628",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1781976","Efficacy and clinical relevance of cognition enhancers.","1781976",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17914184","Effects of dietary supplementation with N-acetyl cysteine, acetyl-L-carnitine and S-adenosyl methionine on cognitive performance and aggression in normal mice and mice expressing human ApoE4.","17914184",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1944900","Long-term acetyl-L-carnitine treatment in Alzheimer's disease.","1944900",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19735717","Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles.","19735717",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20359271","Acetyl-L-carnitine. Monograph.","20359271",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2140973","[Effects of L-acetylcarnitine on mental deterioration in the aged: initial results].","2140973",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2201659","Acetyl-L-carnitine in the treatment of mildly demented elderly patients.","2201659",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23227269","Acetyl-L-carnitine improves behavior and dendritic morphology in a mouse model of Rett syndrome.","23227269",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24018499","Oral acetyl-L-carnitine treatment in hepatic encephalopathy: view of evidence-based medicine.","24018499",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26374445","Mitochondrial modulators improve lipid composition and attenuate memory deficits in experimental model of Huntington's disease.","26374445",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26481404","Effect of mitochondrial cofactors and antioxidants supplementation on cognition in the aged canine.","26481404",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"7682930","The effect of levo-acetyl-carnitine on visual cognitive evoked potentials in the behaving monkey.","7682930",42]
["Acetylcarnitine","Acetylcarnitine","D000108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7813389","L-acetylcarnitine treatment of mental decline in the elderly.","7813389",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11030481","Paying attention to your acetylcholine, Part 2: the function of nicotinic receptors.","11030481",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11728425","SCH 57790, a selective muscarinic M(2) receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals.","11728425",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12020863","Effects of estrogen on acetylcholine release in frontal cortex of female rats: involvement of serotonergic neuronal systems.","12020863",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1382167","Angiotensin-converting enzyme inhibition, angiotensin, and cognition.","1382167",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15183504","Intraseptal muscarinic ligands and galanin: influence on hippocampal acetylcholine and cognition.","15183504",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15795051","Estrogen modulates cognitive and cholinergic processes in surgically menopausal monkeys.","15795051",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15951399","Lecozotan (SRA-333): a selective serotonin 1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties.","15951399",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16298243","Inhibition of hippocampal function in mild cognitive impairment: targeting the cholinergic hypothesis.","16298243",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1662399","Effect of a new cognition enhancer, alpha-glycerylphosphorylcholine, on scopolamine-induced amnesia and brain acetylcholine.","1662399",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16801977","The procholinergic effects of the atypical antipsychotic olanzapine are independent of muscarinic autoreceptor inhibition.","16801977",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17195650","[Experience with gliatilin treatment of patients with intracranial neoplasia].","17195650",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17619614","[EEG and clinical psychophysiological study of functional changes in the chronic ischemic brain with increased acetylcholinergic activity].","17619614",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17692343","VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux.","17692343",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17928814","The role of acetylcholine in cocaine addiction.","17928814",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18289004","Pathways of acetylcholine synthesis, transport and release as targets for treatment of adult-onset cognitive dysfunction.","18289004",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18373034","Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: critical role of S-adenosyl methionine.","18373034",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21704049","Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats.","21704049",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7869110","Facilitation of acetylcholine release and cognitive performance by an M(2)-muscarinic receptor antagonist in aged memory-impaired.","7869110",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8624125","The D1 agonist dihydrexidine releases acetylcholine and improves cognition in rats.","8624125",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9446713","Tacrine administration enhances extracellular acetylcholine in vivo and restores the cognitive impairment in aged rats.","9446713",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18706897","Increasing hippocampal acetylcholine levels enhance behavioral performance in an animal model of diencephalic amnesia.","18706897",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19345233","JNJ-10181457, a selective non-imidazole histamine H(3) receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition.","19345233",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20147893","Enhancement of attentional performance by selective stimulation of alpha4beta2(*) nAChRs: underlying cholinergic mechanisms.","20147893",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21108972","Acetylcholine and attention.","21108972",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22784425","Ginkgo biloba leaf extract (EGb 761®) and its specific acylated flavonol constituents increase dopamine and acetylcholine levels in the rat medial prefrontal cortex: possible implications for the cognitive enhancing properties of EGb 761®.","22784425",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23449490","Novel cognitive enhancer ST101 enhances acetylcholine release in mouse dorsal hippocampus through T-type voltage-gated calcium channel stimulation.","23449490",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2356203","Low dose tetrahydroaminoacridine (THA) improves cognitive function but does not affect brain acetylcholine in rats.","2356203",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24292380","Combination effects of ZSET1446/ST101 with memantine on cognitive function and extracellular acetylcholine in the hippocampus.","24292380",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24937053","Lack of synaptic vesicle protein SV2B protects against amyloid-β₂₅₋₃₅-induced oxidative stress, cholinergic deficit and cognitive impairment in mice.","24937053",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26003527","The muscarinic system, cognition and schizophrenia.","26003527",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2602443","The relationship between the behavioral effects of cognition-enhancing drugs and brain acetylcholine. Nootropic drugs and brain acetylcholine.","2602443",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27112419","Cereboost™, an American ginseng extract, improves cognitive function via up-regulation of choline acetyltransferase expression and neuroprotection.","27112419",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27208489","Subtle learning and memory impairment in an idiopathic rat model of Alzheimer's disease utilizing cholinergic depletions and β-amyloid.","27208489",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28916328","Primary hippocampal neuronal cell death induction after acute and repeated paraquat exposures mediated by AChE variants alteration and cholinergic and glutamatergic transmission disruption.","28916328",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3048527","Acetylcholine and Alzheimer's disease.","3048527",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8041485","Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition.","8041485",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8129838","The role of acetylcholine in the cognitive function of frontal neurons in monkeys.","8129838",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8201605","Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 1. Tropic and 2-phenylpropionic acid esters.","8201605",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8201606","Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 2. 2-Phenoxy-, 2-(phenylthio)-, and 2-(phenylamino)alkanoic acid esters.","8201606",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8382283","Presynaptic cholinergic actions by the putative cognitive enhancing agent DuP 996.","8382283",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8388315","Effects of cytidine-diphosphocholine on acetylcholine-mediated behaviors in the rat.","8388315",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8806034","Neuronal mechanisms mediating drug-induced cognition enhancement: cognitive activity as a necessary intervening variable.","8806034",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8848095","Dopamine D1 receptor ligands modulate cognitive performance and hippocampal acetylcholine release in memory-impaired aged rats.","8848095",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C323,B323)","v":"Acetylcholine"},"Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J323,K323)","v":"Cognition"},"D003071","Cognition",0,1,1996,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q323,Q323)","v":"8982515"},"Inhibition of cortical acetylcholine release and cognitive performance by histamine H3 receptor activation in rats.","8982515",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9062654","Trans-synaptic stimulation of cortical acetylcholine and enhancement of attentional functions: a rational approach for the development of cognition enhancers.","9062654",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9300608","D1 agonist dihydrexidine releases acetylcholine and improves cognitive performance in rats.","9300608",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9510426","The role of the central cholinergic projections in cognition: implications of the effects of scopolamine on discrimination learning by monkeys.","9510426",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9725745","Nicotinic acetylcholine involvement in cognitive function in animals.","9725745",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9795096","Inhibition of hippocampal acetylcholine release after acute and repeated Delta9-tetrahydrocannabinol in rats.","9795096",42]
["Acetylcholine","Acetylcholine","D000109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"9894570","Pharmacologic strategies for augmenting cognitive performance in schizophrenia.","9894570",42]
["Aconitine","Aconitine","D000157","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11303051","Effect of FK960, a putative cognitive enhancer, on synaptic transmission in CA1 neurons of rat hippocampus.","11303051",42]
["Acrolein","Acrolein","D000171","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23296102","Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo.","23296102",42]
["Acrolein","Acrolein","D000171","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27387400","Reversal of diabetes-induced behavioral and neurochemical deficits by cinnamaldehyde.","27387400",42]
["acteoside","acteoside","C058956","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16394513","Acteoside of Callicarpa dichotoma attenuates scopolamine-induced memory impairments.","16394513",42]
["Actihaemyl","Actihaemyl","D000183","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8993675","Solcoseryl improves learning and memory in rats.","8993675",42]
["Actovegin","Actovegin","C015646","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2132641","Topographic mapping of cognitive event-related potentials in a double-blind, placebo-controlled study with the hemoderivative Actovegin in age-associated memory impairment.","2132641",42]
["Actovegin","Actovegin","C015646","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22379876","[Neuroprotector therapy of patients with decompensated diabetes mellitus type 1].","22379876",42]
["Actovegin","Actovegin","C015646","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23994934","[Efficacy of actovegin in the treatment of elderly patients with vascular mild cognitive impairment].","23994934",42]
["Acyclovir","Acyclovir","D000212","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10579665","Cognitive outcome after emergent treatment of acute herpes simplex encephalitis with acyclovir.","10579665",42]
["Acyclovir","Acyclovir","D000212","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27218417","Clinical outcomes in children with herpes simplex encephalitis receiving steroid therapy.","27218417",42]
["adafenoxate","adafenoxate","C054061","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2511850","Memory effects of the new derivative of the p-chlorophenoxyacetic acid adafenoxate compared to the effects of some cognition-enhancing drugs in rats.","2511850",42]
["adafenoxate","adafenoxate","C054061","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8412411","Adafenoxate abolishes the amnesia induced by neonatal 6-hydroxydopamine treatment in rats.","8412411",42]
["Adamantane","Adamantane","D000218","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18308776","Selectively increased trace conditioning under the neurotensin agonist PD 149163 in an aversive procedure in which SR 142948A was without intrinsic effect.","18308776",42]
["Adamantane","Adamantane","D000218","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19154630","The effect of a full agonist/antagonist of the D1 receptor on locomotor activity, sensorimotor gating and cognitive function in dizocilpine-treated rats.","19154630",42]
["Adamantane","Adamantane","D000218","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20600002","Neurotrophic peptides incorporating adamantane improve learning and memory, promote neurogenesis and synaptic plasticity in mice.","20600002",42]
["Adamantane","Adamantane","D000218","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23240760","DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption.","23240760",42]
["Adamantane","Adamantane","D000218","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23323324","[Study of hemantane effects in rats on a model of early (premotor) stage of Parkinson's disease].","23323324",42]
["Adamantane","Adamantane","D000218","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23848558","Cognitive and functional influences of vildagliptin, a DPP-4 inhibitor, added to ongoing metformin therapy in elderly with type 2 diabetes.","23848558",42]
["Adamantane","Adamantane","D000218","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26016746","Dipeptidyl peptidase 4 inhibitor improves brain insulin sensitivity, but fails to prevent cognitive impairment in orchiectomy obese rats.","26016746",42]
["Adamantane","Adamantane","D000218","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26607467","Favorable effects of vildagliptin on metabolic and cognitive dysfunctions in streptozotocin-induced diabetic rats.","26607467",42]
["Adderall","Adderall","C090411","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19011838","When we enhance cognition with Adderall, do we sacrifice creativity? A preliminary study.","19011838",42]
["Adderall","Adderall","C090411","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22884611","Objective and subjective cognitive enhancing effects of mixed amphetamine salts in healthy people.","22884611",42]
["Adenine","Adenine","D000225","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21598628","[Effect of new adenine derivative on emotional status of rats under conditions of \"voluntary alcoholization\" model].","21598628",42]
["adinazolam","adinazolam","C039668","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7480549","Comparison of the spectrum of cognitive effects of alprazolam and adinazolam after single doses in healthy subjects.","7480549",42]
["adrafinil","adrafinil","C022116","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11191710","Adrafinil: effects on behavior and cognition in aged canines.","11191710",42]
["adrogolide hydrochloride","adrogolide hydrochloride","C095428","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11607045","Adrogolide HCl (ABT-431; DAS-431), a prodrug of the dopamine D1 receptor agonist, A-86929: preclinical pharmacology and clinical data.","11607045",42]
["agroclavine","agroclavine","C004465","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11840962","[Effect of a dopamine agonist on working memory in monkeys].","11840962",42]
["Albuterol","Albuterol","D000420","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9001297","Inhaled salmeterol or oral theophylline in nocturnal asthma?","9001297",42]
["Alendronate","Alendronate","D019386","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15010082","Neuropsychological and emotional changes during simulated microgravity: effects of triiodothyronine alendronate, and testosterone.","15010082",42]
["Alfaxalone Alfadolone Mixture","Alfaxalone Alfadolone Mixture","D000530","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1975,"241272","[Comparative study of post-anesthesia awakening and behavior following alfatesine and pentothal].","241272",42]
["Alfentanil","Alfentanil","D015760","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10422934","Optimal propofol-alfentanil combinations for supplementing nitrous oxide for outpatient surgery.","10422934",42]
["Alfentanil","Alfentanil","D015760","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1443715","Time-course of respiratory depression after an alfentanil infusion-based anesthetic.","1443715",42]
["Alfentanil","Alfentanil","D015760","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1874219","Awakening and recovery of simple cognitive and psychomotor functions 2 h after anaesthesia for day-case surgery--total intravenous anaesthesia with propofol-alfentanil versus thiopentone-alfentanil.","1874219",42]
["Alfentanil","Alfentanil","D015760","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2327227","Awareness and general anaesthesia.","2327227",42]
["Alfentanil","Alfentanil","D015760","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2378773","Total i.v. anaesthesia with propofol-alfentanil or propofol-fentanyl.","2378773",42]
["Alfentanil","Alfentanil","D015760","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2491936","Neuroleptanalgesia using alfentanil for awake craniotomy.","2491936",42]
["Alfentanil","Alfentanil","D015760","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9620514","Analgesic and cognitive effects of intravenous ketamine-alfentanil combinations versus either drug alone after intradermal capsaicin in normal subjects.","9620514",42]
["Allantoin","Allantoin","D000481","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24296131","Effects of allantoin on cognitive function and hippocampal neurogenesis.","24296131",42]
["Allopurinol","Allopurinol","D000493","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25845300","Allopurinol reduces severity of delayed neurologic sequelae in experimental carbon monoxide toxicity in rats.","25845300",42]
["Almitrine","Almitrine","D015765","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3415398","Double-blind, placebo-controlled quantitative EEG and psychometric studies in elderlies on vigilance-promoting effects of an almitrine/raubasine combination (Duxil).","3415398",42]
["almitrine, raubasine drug combination","almitrine, raubasine drug combination","C037558","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3415398","Double-blind, placebo-controlled quantitative EEG and psychometric studies in elderlies on vigilance-promoting effects of an almitrine/raubasine combination (Duxil).","3415398",42]
["alpha5IA-II","alpha5IA-II","C510446","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18482097","GABA(A) receptor subtype-selective efficacy: TPA023, an alpha2/alpha3 selective non-sedating anxiolytic and alpha5IA, an alpha5 selective cognition enhancer.","18482097",42]
["alpha5IA-II","alpha5IA-II","C510446","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21050171","GABAA receptor subtype-selective modulators. II. α5-selective inverse agonists for cognition enhancement.","21050171",42]
["alpha-hydroxyglutarate","alpha-hydroxyglutarate","C019417","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18343698","Riboflavin treatment in a case with l-2-hydroxyglutaric aciduria.","18343698",42]
["alpha-Linolenic Acid","alpha-Linolenic Acid","D017962","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14643178","Alpha-linolenic acid supplementation during human pregnancy does not effect cognitive functioning.","14643178",42]
["alpha-Linolenic Acid","alpha-Linolenic Acid","D017962","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24928171","Providing male rats deficient in iron and n-3 fatty acids with iron and alpha-linolenic acid alone affects brain serotonin and cognition differently from combined provision.","24928171",42]
["alpha-Linolenic Acid","alpha-Linolenic Acid","D017962","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26386148","Repeated systemic administration of the nutraceutical alpha-linolenic acid exerts neuroprotective efficacy, an antidepressant effect and improves cognitive performance when given after soman exposure.","26386148",42]
["alpha-Linolenic Acid","alpha-Linolenic Acid","D017962","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26569216","α-Linolenic Acid, A Nutraceutical with Pleiotropic Properties That Targets Endogenous Neuroprotective Pathways to Protect against Organophosphate Nerve Agent-Induced Neuropathology.","26569216",42]
["alpha-Tocopherol","alpha-Tocopherol","D024502","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14716777","Phase II study of alpha-tocopherol in improving the cognitive function of patients with temporal lobe radionecrosis.","14716777",42]
["alpha-Tocopherol","alpha-Tocopherol","D024502","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25149567","Coenzyme Q10 and α-tocopherol reversed age-associated functional impairments in mice.","25149567",42]
["alpha-Tocopherol","alpha-Tocopherol","D024502","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25187257","A combination of ascorbic acid and α-tocopherol to test the effectiveness and safety in the fragile X syndrome: study protocol for a phase II, randomized, placebo-controlled trial.","25187257",42]
["alpha-Tocopherol","alpha-Tocopherol","D024502","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26414867","Chronic α-Tocopherol Increases Central Monoamines Synthesis and Improves Cognitive and Motor Abilities in Old Rats.","26414867",42]
["alpha-Tocopherol","alpha-Tocopherol","D024502","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27983697","α-Tocopherol and Hippocampal Neural Plasticity in Physiological and Pathological Conditions.","27983697",42]
["alpha-Tocopherol","alpha-Tocopherol","D024502","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28418065","Vitamin E for Alzheimer's dementia and mild cognitive impairment.","28418065",42]
["alpidem","alpidem","C052036","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"1974070","Effects of single doses of alpidem, lorazepam, and placebo on memory and attention in healthy young and elderly volunteers.","1974070",42]
["alpidem","alpidem","C052036","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"2883214","Pharmacokinetic and dynamic studies with a new anxiolytic imidazo-pyridine alpidem utilizing pharmaco-EEG and psychometry.","2883214",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15765256","Effects of CRF1 receptor antagonists and benzodiazepines in the Morris water maze and delayed non-matching to position tests.","15765256",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C387,B387)","v":"Alprazolam"},"Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J387,K387)","v":"Cognition"},"D003071","Cognition",0,1,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q387,Q387)","v":"16001108"},"Sex-related elevation in cortisol during chronic treatment with alprazolam associated with enhanced cognitive performance.","16001108",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16205916","A double-blind, placebo- and positive-internal-controlled (alprazolam) investigation of the cognitive and psychomotor profile of pregabalin in healthy volunteers.","16205916",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16572266","A statistical approach for classifying change in cognitive function in individuals following pharmacologic challenge: an example with alprazolam.","16572266",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17094673","[The cognitive effect of alprazolam in healthy volunteers].","17094673",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17219217","Cognitive, psychomotor and actual driving performance in healthy volunteers after immediate and extended release formulations of alprazolam 1 mg.","17219217",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"21693549","Switching from long-term benzodiazepine therapy to pregabalin in patients with generalized anxiety disorder: a double-blind, placebo-controlled trial.","21693549",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1984710","Effects of buspirone and alprazolam on the cognitive performance of normal elderly subjects.","1984710",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"2050170","The effects of repeated doses of clomipramine and alprazolam on physiological, psychomotor and cognitive functions in normal subjects.","2050170",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2276384","Effects of single doses of alprazolam and diazepam, alone and in combination with ethanol, on psychomotor and cognitive performance and on autonomic nervous system reactivity in healthy volunteers.","2276384",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25199955","Inhaled vs. oral alprazolam: subjective, behavioral and cognitive effects, and modestly increased abuse potential.","25199955",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27462136","The Effect of Chronic Alprazolam Intake on Memory, Attention, and Psychomotor Performance in Healthy Human Male Volunteers.","27462136",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7480549","Comparison of the spectrum of cognitive effects of alprazolam and adinazolam after single doses in healthy subjects.","7480549",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7697954","Alprazolam absorption kinetics affects abuse liability.","7697954",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8665994","Acute effects of the anxiolytics suriclone and alprazolam on cognitive information processing utilizing topographic mapping of event-related brain potentials (P300) in healthy subjects.","8665994",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9790153","Alprazolam 0.125 mg twice a day improves aspects of psychometric performance in healthy volunteers.","9790153",42]
["Alprazolam","Alprazolam","D000525","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9833000","Behavioral effects of alprazolam in humans.","9833000",42]
["altinicline maleate","altinicline maleate","C100989","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9506547","Effects of the nicotinic acetylcholine receptor agonist SIB-1508Y on object retrieval performance in MPTP-treated monkeys: comparison with levodopa treatment.","9506547",42]
["aluminum chloride","aluminum chloride","C010845","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18817812","Aluminium-induced electrophysiological, biochemical and cognitive modifications in the hippocampus of aging rats.","18817812",42]
["aluminum chloride","aluminum chloride","C010845","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23535404","Effects of subchronic aluminum exposure on spatial memory, ultrastructure and L-LTP of hippocampus in rats.","23535404",42]
["aluminum chloride","aluminum chloride","C010845","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26946116","Aluminum chloride induces neuroinflammation, loss of neuronal dendritic spine and cognition impairment in developing rat.","26946116",42]
["Aluminum Hydroxide","Aluminum Hydroxide","D000536","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17966072","Effects of acute exposure to aluminum on cognition in humans.","17966072",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10579658","Cognitive and behavioural efficacy of amantadine in acute traumatic brain injury: an initial double-blind placebo-controlled study.","10579658",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10721881","Amantadine influences cognitive processing in patients with multiple sclerosis.","10721881",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10907729","Short-term effect of amantadine sulphate on motor performance and reaction time in patients with idiopathic Parkinson's disease.","10907729",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11793161","The visuo-cognitive and motor effect of amantadine in non-Caucasian patients with Parkinson's disease. A clinical and electrophysiological study.","11793161",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12221159","Huntington's disease: a randomized, controlled trial using the NMDA-antagonist amantadine.","12221159",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1388702","Topographic mapping of long latency \"cognitive\" event-related potentials (P 300): a double-blind, placebo-controlled study with amantadine in mild dementia.","1388702",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15624567","Amantadine in pediatric patients with traumatic brain injury: a retrospective, case-controlled study.","15624567",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16192841","A double-blind, cross-over comparison of the effects of amantadine or placebo on visuomotor and cognitive function in medicated schizophrenia patients.","16192841",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18212258","Amantadine enhancement of arousal and cognition after traumatic brain injury.","18212258",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8639070","The effects of amantadine and pemoline on cognitive functioning in multiple sclerosis.","8639070",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"21121175","Effects of amantadine on tardive dyskinesia: a randomized, double-blind, placebo-controlled study.","21121175",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"21287796","Effect of antiviral amantadine treatment on elderly chronic schizophrenia patients.","21287796",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"21308277","Mania switch induced by amantadine in bipolar disorder: report of three cases.","21308277",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22613947","Efficacy of amantadine treatment on symptoms and neurocognitive performance among adolescents following sports-related concussion.","22613947",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"23574258","Amantadine improves cognitive outcome and increases neuronal survival after fluid percussion traumatic brain injury in rats.","23574258",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24497943","Amantadine ameliorates dopamine-releasing deficits and behavioral deficits in rats after fluid percussion injury.","24497943",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26466744","Antidepressant-like effects and possible mechanisms of amantadine on cognitive and synaptic deficits in a rat model of chronic stress.","26466744",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9171930","The combined use of amantadine and l-dopa/carbidopa in the treatment of chronic brain injury.","9171930",42]
["amibegron","amibegron","C076252","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17460614","Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders.","17460614",42]
["Amiloride","Amiloride","D000584","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15466959","Amiloride increases neuronal damage after traumatic brain injury in rats.","15466959",42]
["Aminacrine","Aminacrine","D000585","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28419192","Efficacy and safety of a novel acetylcholinesterase inhibitor octohydroaminoacridine in mild-to-moderate Alzheimer's disease: a Phase II multicenter randomised controlled trial.","28419192",42]
["Aminophylline","Aminophylline","D000628","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12094921","Effect of aminophylline on recovery from sevoflurane anaesthesia.","12094921",42]
["Aminophylline","Aminophylline","D000628","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20160462","Protective effects of methylxanthines on hypoxia-induced apoptotic neurodegeneration and long-term cognitive functions in the developing rat brain.","20160462",42]
["Aminophylline","Aminophylline","D000628","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21755342","Effects of aminophylline on cognitive recovery after sevoflurane anesthesia.","21755342",42]
["amiridine","amiridine","C049860","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1664616","[Effectiveness of amiridin in senile dementia of the Alzheimer type].","1664616",42]
["amiridine","amiridine","C049860","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"18379458","[Neuromidin in the treatment of vascular cognitive disorders].","18379458",42]
["amiridine","amiridine","C049860","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23612399","[Neuromidin in the treatment of cognitive impairment in the early rehabilitation period of ischemic stroke].","23612399",42]
["amiridine","amiridine","C049860","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8312813","[The effect of amiridin on the spectral characteristics of the human EEG].","8312813",42]
["amiridine","amiridine","C049860","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8464548","The effectiveness of amiridin in senile dementia of the Alzheimer's type.","8464548",42]
["amiridine","amiridine","C049860","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9762718","Residual lesions of operant behavior in monkeys following recovery from MPTP-induced Parkinson-like syndrome.","9762718",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11850470","Chronic treatment with the antidepressant amitriptyline prevents impairments in water maze learning in aging rats.","11850470",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12236848","The effects of St John's wort extract on heart rate variability, cognitive function and quantitative EEG: a comparison with amitriptyline and placebo in healthy men.","12236848",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12590402","Mirtazapine in combination with amitriptyline: a drug-drug interaction study in healthy subjects.","12590402",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1523282","Amitriptyline, clovoxamine and cognitive function: a placebo-controlled comparison in depressed outpatients.","1523282",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9443520","Lack of sedative and cognitive effects of diphenhydramine and cyclobenzaprine in elderly volunteers.","9443520",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18383000","The effects of acute treatment with paroxetine, amitriptyline, and placebo on driving performance and cognitive function in healthy Japanese subjects: a double-blind crossover trial.","18383000",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2682593","Actions and interactions of psychotropic drugs on human performance and mood: single doses of ORG 3770, amitriptyline, and diazepam.","2682593",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3421584","Amitriptyline and asymptomatic hypoglycemia.","3421584",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3700344","A comparison of the effects of trazodone and amitriptyline on skills performance by geriatric subjects.","3700344",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3725002","Evaluation of possible interactions between ethanol and trazodone or amitriptyline.","3725002",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3725003","Cognitive performance in geriatric subjects after acute treatment with antidepressants.","3725003",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1983,"6230891","Effects of amitriptyline, desipramine and zimeldine, alone and in combination with ethanol, on information processing and memory in healthy volunteers.","6230891",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6431462","Amoxapine and amitriptyline. II. Specificity of cognitive effects during brief treatment of depression.","6431462",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C451,B451)","v":"Amitriptyline"},"Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J451,K451)","v":"Cognition"},"D003071","Cognition",0,1,1993,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q451,Q451)","v":"8277161"},"Effects of fluoxetine on psychomotor performance, cognitive function and sleep in depressed patients.","8277161",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8471403","A placebo controlled double-blind evaluation of the pharmacodynamics of fengabine vs amitriptyline following single and multiple doses in elderly volunteers.","8471403",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8864325","The effects of reboxetine and amitriptyline, with and without alcohol on cognitive function and psychomotor performance.","8864325",42]
["Amitriptyline","Amitriptyline","D000639","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9728902","Cognitive performance in elderly subjects after a single dose of befloxatone, a new reversible selective monoamine oxidase A inhibitor.","9728902",42]
["Amlodipine","Amlodipine","D017311","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19394790","Measures of cognitive functioning as predictors of treatment outcome for cocaine dependence.","19394790",42]
["Amlodipine","Amlodipine","D017311","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22664571","Combination therapy of atorvastatin and amlodipine inhibits sympathetic nervous system activation and improves cognitive function in hypertensive rats.","22664571",42]
["Amlodipine","Amlodipine","D017311","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25229168","Comparison of effects of valsartan and amlodipine on cognitive functions and auditory p300 event-related potentials in elderly hypertensive patients.","25229168",42]
["Amlodipine","Amlodipine","D017311","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27430267","A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol.","27430267",42]
["Amlodipine","Amlodipine","D017311","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8382234","Double-blind, parallel, comparative study on quality of life during treatment with amlodipine or enalapril in mild or moderate hypertensive patients: a multicentre study.","8382234",42]
["Ammonia","Ammonia","D000641","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10566738","Effect of lactitol on blood ammonia response to oral glutamine challenge in cirrhotic patients: evidence for an effect of nonabsorbable disaccharides on small intestine ammonia generation.","10566738",42]
["Ammonia","Ammonia","D000641","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22083566","Exploratory investigation on nitro- and phospho-proteome cerebellum changes in hyperammonemia and hepatic encephalopathy rat models.","22083566",42]
["Ammonia","Ammonia","D000641","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27126704","Multidimensional assessment of self-reported chemical intolerance and its impact on chemosensory effects during ammonia exposure.","27126704",42]
["Amobarbital","Amobarbital","D000654","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1977,"16635","A repeated dose comparison of dichloralphenazone, flunitrazepam and amylobarbitone sodium on some aspects of sleep and early morning behaviour in normal subjects.","16635",42]
["Amobarbital","Amobarbital","D000654","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22396439","Who needs a Wada test? Present clinical indications for amobarbital procedures.","22396439",42]
["Amobarbital","Amobarbital","D000654","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1973,"4692490","Barbiturate tolerance and psychological functioning in elderly depressed patients.","4692490",42]
["Amobarbital","Amobarbital","D000654","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1969,"4900733","Effects of nitrazepam, amylobarbitone and placebo on some perceptual, motor and cognitive tasks in normal subjects.","4900733",42]
["Amobarbital","Amobarbital","D000654","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1970,"4942686","Objective effects of dexamphetamine and amobarbital and their relations to psychasthenic personality traits.","4942686",42]
["Amobarbital","Amobarbital","D000654","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1978,"665813","False positives in the differential diagnosis of confusion with amytal.","665813",42]
["Amobarbital","Amobarbital","D000654","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9892047","Independent recovery of memory and language functioning during the Intracarotid Sodium Amytal Test.","9892047",42]
["Amodiaquine","Amodiaquine","D000655","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18620950","Effect of intermittent preventive treatment of malaria on health and education in schoolchildren: a cluster-randomised, double-blind, placebo-controlled trial.","18620950",42]
["Amoxapine","Amoxapine","D000657","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6431462","Amoxapine and amitriptyline. II. Specificity of cognitive effects during brief treatment of depression.","6431462",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11129500","Avoidance responding following amphetamine-induced dopamine depletion.","11129500",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11329494","Individual differences in responses to ethanol and d-amphetamine: a within-subject study.","11329494",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12622347","Variations in affect following amphetamine and placebo: markers of stimulant drug preference.","12622347",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15508024","Cognitive sequelae of intravenous amphetamine self-administration in rats: evidence for selective effects on attentional performance.","15508024",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15607687","Spontaneous individual differences in cognitive performances of young adult rats predict locomotor response to amphetamine.","15607687",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16005384","Amphetamine improves cognitive function in medicated individuals with schizophrenia and in healthy volunteers.","16005384",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16143730","Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model psychoses and cognitive function.","16143730",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16237395","Amphetamine-induced displacement of [18F] fallypride in striatum and extrastriatal regions in humans.","16237395",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16343411","Impairment related to blood amphetamine and/or methamphetamine concentrations in suspected drugged drivers.","16343411",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17047670","A sensitizing regimen of amphetamine impairs visual attention in the 5-choice serial reaction time test: reversal by a D1 receptor agonist injected into the medial prefrontal cortex.","17047670",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17934180","Medications do not necessarily normalize cognition in ADHD patients.","17934180",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18481035","Effects of l-amphetamine sulfate on cognitive function in multiple sclerosis patients.","18481035",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19263186","The effects of L-amphetamine sulfate on cognition in MS patients: results of a randomized controlled trial.","19263186",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20600252","Reversal of neuronal and cognitive consequences of amphetamine sensitization following chronic treatment with a D1 antagonist.","20600252",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20947305","Amphetamine-related improvement in executive function in patients with chronic schizophrenia is modulated by practice effects.","20947305",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21300940","Functional magnetic resonance imaging investigation of the amphetamine sensitization model of schizophrenia in healthy male volunteers.","21300940",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"21812875","Periadolescent amphetamine treatment causes transient cognitive disruptions and long-term changes in hippocampal LTP depending on the endogenous expression of pleiotrophin.","21812875",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21813688","Repeated amphetamine exposure disrupts dopaminergic modulation of amygdala-prefrontal circuitry and cognitive/emotional functioning.","21813688",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22312969","[Effects of marijuana and amphetamine (and its derivatives on driving performance based on the driving simulator studies].","22312969",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23314393","Amphetamine effects on MATRICS Consensus Cognitive Battery performance in healthy adults.","23314393",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23767434","Prohibition or coffee shops: regulation of amphetamine and methylphenidate for enhancement use by healthy adults.","23767434",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24907495","Comparing stimulant effects in youth with ADHD symptoms and epilepsy.","24907495",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26289355","Effects of single dose mixed amphetamine salts--extended release on processing speed in multiple sclerosis: a double blind placebo controlled study.","26289355",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27469022","Improvement of attention with amphetamine in low- and high-performing rats.","27469022",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28661714","Early Initiation of Amphetamine-Type Stimulants (ATS) Use Associated with Lowered Cognitive Performance among Individuals with Co-Occurring Opioid and ATS Use Disorders in Malaysia.","28661714",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28686989","Mixed-amphetamine salts expectancies among college students: Is stimulant induced cognitive enhancement a placebo effect?","28686989",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1974,"4599412","Stereospecific actions of DOET (2,5-dimethoxy-4-ethylamphetamine) in man.","4599412",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1973,"4701964","Marijuana and amphetamine: the question of interaction.","4701964",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7491392","Neuropsychological effects of amphetamine may correlate with personality characteristics.","7491392",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7617813","Psychopharmacological studies in rats responding at touch-sensitive devices.","7617813",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8115427","Chronic L-deprenyl or L-amphetamine: equal cognitive enhancement, unequal MAO inhibition.","8115427",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8412415","Clinical-pharmacological study with the two isomers (d-, l-) of fenfluramine and its comparison with chlorpromazine and d-amphetamine: psychometric and psychophysiological evaluation.","8412415",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8988462","Are metabolites of l-deprenyl (selegiline) useful or harmful? Indications from preclinical research.","8988462",42]
["anandamide","anandamide","C078814","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10762668","Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice.","10762668",42]
["anandamide","anandamide","C078814","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26363193","Anandamide mediates cognitive judgement bias in rats.","26363193",42]
["anandamide","anandamide","C078814","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26826191","Comparisons of Δ9-Tetrahydrocannabinol and Anandamide on a Battery of Cognition-Related Behavior in Nonhuman Primates.","26826191",42]
["anandamide","anandamide","C078814","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28789932","The effects of anandamide and oleamide on cognition depend on diurnal variations.","28789932",42]
["anapsos","anapsos","C006870","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11196347","Double-blind, randomized, placebo-controlled pilot study with anapsos in senile dementia: effects on cognition, brain bioelectrical activity and cerebral hemodynamics.","11196347",42]
["anapsos","anapsos","C006870","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11261800","A pharmacogenomic approach to Alzheimer's disease.","11261800",42]
["anastrozole","anastrozole","C090450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14623538","The effects of hormone therapy on cognition in breast cancer.","14623538",42]
["anastrozole","anastrozole","C090450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18768369","Effects of anastrozole on cognitive performance in postmenopausal women: a randomised, double-blind chemoprevention trial (IBIS II).","18768369",42]
["anastrozole","anastrozole","C090450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"19071243","Anastrozole: brain draining or sparing?","19071243",42]
["anastrozole","anastrozole","C090450","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25906766","Patterns of change in cognitive function with anastrozole therapy.","25906766",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C515,B515)","v":"andrographolide"},"andrographolide","C030419","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J515,K515)","v":"Cognition"},"D003071","Cognition",0,1,2016,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q515,Q515)","v":"26810454"},"Beneficial effects of an Andrographis paniculata extract and andrographolide on cognitive functions in streptozotocin-induced diabetic rats.","26810454",42]
["anemoside A3","anemoside A3","C473640","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25649278","Anemoside A3 Enhances Cognition through the Regulation of Synaptic Function and Neuroprotection.","25649278",42]
["aniracetam","aniracetam","C036466","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15459084","Nootropic agents enhance the recruitment of fast GABAA inhibition in rat neocortex.","15459084",42]
["aniracetam","aniracetam","C036466","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1611039","Aniracetam improves radial maze performance in rats.","1611039",42]
["aniracetam","aniracetam","C036466","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"1971306","Synthesis of valproyl-2-pyrrolidinone and its evaluation as a cognitive drug with the ability to modulate acidic amino acids in the brain.","1971306",42]
["aniracetam","aniracetam","C036466","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25099639","Aniracetam does not alter cognitive and affective behavior in adult C57BL/6J mice.","25099639",42]
["aniracetam","aniracetam","C036466","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"4011635","Effects of aniracetam on delayed matching-to-sample performance of monkeys and pigeons.","4011635",42]
["aniracetam","aniracetam","C036466","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8808132","Aniracetam restores object recognition impaired by age, scopolamine, and nucleus basalis lesions.","8808132",42]
["anisodamine","anisodamine","C003922","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19756370","Peripheral cholinoceptor antagonist anisodamine counteracts cholinergic adverse effects and facilitates cognitive amelioration of rivastigmine.","19756370",42]
["anisodamine","anisodamine","C003922","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8575045","[Anisodamine (654-2) improves impaired cognitive function induced by experimental brain damage].","8575045",42]
["Antipyrine","Antipyrine","D000983","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1977,"16635","A repeated dose comparison of dichloralphenazone, flunitrazepam and amylobarbitone sodium on some aspects of sleep and early morning behaviour in normal subjects.","16635",42]
["Antipyrine","Antipyrine","D000983","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22982593","Attenuation of axonal injury and oxidative stress by edaravone protects against cognitive impairments after traumatic brain injury.","22982593",42]
["Antipyrine","Antipyrine","D000983","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27492363","Edaravone alleviates cisplatin-induced neurobehavioral deficits via modulation of oxidative stress and inflammatory mediators in the rat hippocampus.","27492363",42]
["Apamin","Apamin","D001030","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10643819","Behavioral effects of apamin, a selective inhibitor of the SK(Ca)-channel, in mice and rats.","10643819",42]
["Apamin","Apamin","D001030","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18561910","Small-conductance Ca(2+)-activated K(+) channels: Heterogeneous affinity in rat brain structures and cognitive modulation by specific blockers.","18561910",42]
["Apamin","Apamin","D001030","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24661728","SK channel blockade reverses cognitive and motor deficits induced by nigrostriatal dopamine lesions in rats.","24661728",42]
["Apigenin","Apigenin","D047310","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12928578","Protective effect of flavonoids against aging- and lipopolysaccharide-induced cognitive impairment in mice.","12928578",42]
["Apigenin","Apigenin","D047310","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25614117","Multifunctional scutellarin-rivastigmine hybrids with cholinergic, antioxidant, biometal chelating and neuroprotective properties for the treatment of Alzheimer's disease.","25614117",42]
["Apigenin","Apigenin","D047310","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27105682","Scutellarin promotes microglia-mediated astrogliosis coupled with improved behavioral function in cerebral ischemia.","27105682",42]
["apigetrin","apigetrin","C057792","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12928578","Protective effect of flavonoids against aging- and lipopolysaccharide-induced cognitive impairment in mice.","12928578",42]
["Apomorphine","Apomorphine","D001058","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"15177065","Apomorphine delays simple reaction time in Parkinsonian patients.","15177065",42]
["Apomorphine","Apomorphine","D001058","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18829269","The dopamine agonist apomorphine differentially affects cognitive performance in alcohol dependent patients and healthy controls.","18829269",42]
["Apomorphine","Apomorphine","D001058","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19110038","Effect of \"enriched environment\" during development on adult rat behavior and response to the dopamine receptor agonist apomorphine.","19110038",42]
["Apomorphine","Apomorphine","D001058","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19834690","Effect of apomorphine on cognitive performance and sensorimotor gating in humans.","19834690",42]
["aprepitant","aprepitant","C114556","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19351798","NK1 receptor antagonism and emotional processing in healthy volunteers.","19351798",42]
["aprepitant","aprepitant","C114556","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23775877","Placebo- and amitriptyline-controlled evaluation of central nervous system effects of the NK1 receptor antagonist aprepitant and intravenous alcohol infusion at pseudo-steady state.","23775877",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16382755","The effect of supplementation of docosahexaenoic acid and arachidonic acid on visual acuity and neurodevelopment in larger preterm infants.","16382755",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15811397","Arachidonic acid improves aged rats' spatial cognition.","15811397",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17240089","Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula.","17240089",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17710956","Roles of long-chain polyunsaturated fatty acids in the term infant: developmental benefits.","17710956",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19505812","Toward optimizing vision and cognition in term infants by dietary docosahexaenoic and arachidonic acid supplementation: a review of randomized controlled trials.","19505812",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19752581","Arachidonic acid supplementation decreases P300 latency and increases P300 amplitude of event-related potentials in healthy elderly men.","19752581",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19765006","Three randomized controlled trials of early long-chain polyunsaturated Fatty Acid supplementation on means-end problem solving in 9-month-olds.","19765006",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20624152","Attention among very low birth weight infants following early supplementation with docosahexaenoic and arachidonic acid.","20624152",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23783296","Effects of long-chain PUFA supplementation in infant formula on cognitive function in later childhood.","23783296",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24521845","Arachidonic acid-enriched triacylglycerol improves cognitive function in elderly with low serum levels of arachidonic acid.","24521845",42]
["Arachidonic Acid","Arachidonic Acid","D016718","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27502791","Growth, metabolic markers, and cognition in 8-year old children born prematurely, follow-up of a randomized controlled trial with essential fatty acids.","27502791",42]
["arachidonyl-2-chloroethylamide","arachidonyl-2-chloroethylamide","C119325","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22451318","CB1 agonist ACEA protects neurons and reduces the cognitive impairment of AβPP/PS1 mice.","22451318",42]
["Arecoline","Arecoline","D001115","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1388279","Ondansetron and arecoline prevent scopolamine-induced cognitive deficits in the marmoset.","1388279",42]
["Arecoline","Arecoline","D001115","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"7871052","Memory improvement without toxicity during chronic, low dose intravenous arecoline in Alzheimer's disease.","7871052",42]
["Arecoline","Arecoline","D001115","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1956992","Effects of acute infusion of the muscarinic cholinergic agonist arecoline on verbal memory and visuo-spatial function in dementia of the Alzheimer type.","1956992",42]
["Arecoline","Arecoline","D001115","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3048224","Multiple-dose arecoline infusions in Alzheimer's disease.","3048224",42]
["Arecoline","Arecoline","D001115","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8840352","Differential response to the cholinergic agonist arecoline among different cognitive modalities in Alzheimer's disease.","8840352",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12383035","Aripiprazole.","12383035",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15517848","Aripiprazole: review of its pharmacology and therapeutic use in psychiatric disorders.","15517848",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16810506","The neurocognitive effects of aripiprazole: an open-label comparison with olanzapine.","16810506",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16900939","Aripiprazole in childhood and adolescence for Tourette syndrome.","16900939",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"18055946","Aripiprazole in the treatment of the psychosis prodrome: an open-label pilot study.","18055946",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18759644","Aripiprazole in children with attention-deficit/hyperactivity disorder.","18759644",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19070440","Subjective, cognitive/psychomotor, and physiological effects of aripiprazole in Chinese light and heavy smokers.","19070440",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20336597","Effect of aripiprazole on cognition in the treatment of patients with schizophrenia.","20336597",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"21616975","Effect of adjunctive treatment with aripiprazole to atypical antipsychotics on cognitive function in schizophrenia patients.","21616975",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22001977","Influence of aripiprazole on the antidepressant, anxiolytic and cognitive functions of rats.","22001977",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22191380","Neurocognitive effects of aripiprazole in adolescents and young adults with bipolar disorder.","22191380",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22766393","Ameliorating effects of aripiprazole on cognitive functions and depressive-like behavior in a genetic rat model of absence epilepsy and mild-depression comorbidity.","22766393",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23131890","Cognitive effects of a single dose of atypical antipsychotics in healthy volunteers compared with placebo or haloperidol.","23131890",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23271192","The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory : A dual [(11)C]raclopride and [(18) F]FDG imaging study with aripiprazole.","23271192",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23308105","Effect of aripiprazole on mismatch negativity (MMN) in schizophrenia.","23308105",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23342824","The neurocognitive effects of aripiprazole compared with risperidone in the treatment of schizophrenia.","23342824",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26556467","Influence of aripiprazole once monthly on clinical symptoms and cognitive function in two schizophrenia patients: Preliminary results.","26556467",42]
["Aripiprazole","Aripiprazole","D000068180","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28272307","Blood Biomarkers Predict the Cognitive Effects of Aripiprazole in Patients with Acute Schizophrenia.","28272307",42]
["armodafinil","armodafinil","C579652","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22960434","Impact of armodafinil on cognition in multiple sclerosis: a randomized, double-blind crossover pilot study.","22960434",42]
["armodafinil","armodafinil","C579652","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23944194","Effect of armodafinil on cognition in patients with HIV/AIDS and fatigue.","23944194",42]
["armodafinil","armodafinil","C579652","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24717254","The effects of armodafinil on objective sleepiness and performance in a shift work disorder sample unselected for objective sleepiness.","24717254",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C579,B579)","v":"armodafinil"},"armodafinil","C579652","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J579,K579)","v":"Cognition"},"D003071","Cognition",0,1,2015,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q579,Q579)","v":"25306261"},"Antipsychotic augmentation with modafinil or armodafinil for negative symptoms of schizophrenia: systematic review and meta-analysis of randomized controlled trials.","25306261",42]
["armodafinil","armodafinil","C579652","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25325498","Effects of armodafinil on simulated driving and alertness in shift work disorder.","25325498",42]
["armodafinil","armodafinil","C579652","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26125538","Armodafinil for fatigue associated with menopause: an open-label trial.","26125538",42]
["Aroclor 1016","Aroclor 1016","C027386","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11543949","Perinatal exposure to polychlorinated biphenyls Aroclor 1016 or 1254 did not alter brain catecholamines nor delayed alternation performance in Long-Evans rats.","11543949",42]
["Aroclor 1016","Aroclor 1016","C027386","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1593987","Use of the lesion model for examining toxicant effects on cognitive behavior.","1593987",42]
["aroclor 1248","aroclor 1248","C028617","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1593987","Use of the lesion model for examining toxicant effects on cognitive behavior.","1593987",42]
["asarone","asarone","C012195","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20460763","Beta-asarone improves cognitive function by suppressing neuronal apoptosis in the beta-amyloid hippocampus injection rats.","20460763",42]
["asarone","asarone","C012195","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22878197","Cognitive enhancing effects of alpha asarone in amnesic mice by influencing cholinergic and antioxidant defense mechanisms.","22878197",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10746596","Association of vitamin E and C supplement use with cognitive function and dementia in elderly men.","10746596",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10994030","Association of vitamin E and C supplement use with cognitive function and dementia in elderly men.","10994030",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12392148","Roles of vitamins E and C on neurodegenerative diseases and cognitive performance.","12392148",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12459890","Effects of fruits and vegetables on levels of vitamins E and C in the brain and their association with cognitive performance.","12459890",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14726220","Effect of vitamins C and E on cognitive function in mouse.","14726220",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16453056","A cross-sectional study of vitamin C and cognitive function in older adults: the differential effects of gender.","16453056",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17508099","Antioxidant intake and cognitive function of elderly men and women: the Cache County Study.","17508099",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18631971","Better cognitive performance in elderly taking antioxidant vitamins E and C supplements in combination with nonsteroidal anti-inflammatory drugs: the Cache County Study.","18631971",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20454891","Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males.","20454891",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20554631","Ameliorative effects of vitamin C on short-term sensorimotor and cognitive changes induced by acute chlorpyrifos exposure in Wistar rats.","20554631",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22558179","Increased expression of SVCT2 in a new mouse model raises ascorbic acid in tissues and protects against paraquat-induced oxidative damage in lung.","22558179",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23128021","Effect of phosphamidon on cognition and oxidative stress and its modulation by ascorbic acid and 4'-chlorodiazepam in rats.","23128021",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24326981","The effect of antioxidant vitamins E and C on cognitive performance of the elderly with mild cognitive impairment in Isfahan, Iran: a double-blind, randomized, placebo-controlled trial.","24326981",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24596461","Cognitive deficits and decreased locomotor activity induced by single-walled carbon nanotubes and neuroprotective effects of ascorbic acid.","24596461",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24699240","Acetylsalicylic acid and ascorbic acid combination improves cognition; via antioxidant effect or increased expression of NMDARs and nAChRs?","24699240",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24763117","Ascorbic acid and the brain: rationale for the use against cognitive decline.","24763117",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24948051","Vitamin C: a new auxiliary treatment of epilepsy?","24948051",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25187257","A combination of ascorbic acid and α-tocopherol to test the effectiveness and safety in the fragile X syndrome: study protocol for a phase II, randomized, placebo-controlled trial.","25187257",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25826870","[Performance evaluation of integrated cytoprotective therapy of different duration in patients with cerebral infarction].","25826870",42]
["Ascorbic Acid","Ascorbic Acid","D001205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9663403","Cohort study of vitamin C intake and cognitive impairment.","9663403",42]
["ascorbic acid, aspirin drug combination","ascorbic acid, aspirin drug combination","C006790","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24699240","Acetylsalicylic acid and ascorbic acid combination improves cognition; via antioxidant effect or increased expression of NMDARs and nAChRs?","24699240",42]
["Asenapine","Asenapine","C522667","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18925388","Asenapine restores cognitive flexibility in rats with medial prefrontal cortex lesions.","18925388",42]
["Asenapine","Asenapine","C522667","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19462162","Asenapine effects in animal models of psychosis and cognitive function.","19462162",42]
["Ashwagandha","Ashwagandha","C030693","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28471731","Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.","28471731",42]
["asiatic acid","asiatic acid","C017032","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22447225","Asiatic acid, a pentacyclic triterpene in Centella asiatica, attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells.","22447225",42]
["asiatic acid","asiatic acid","C017032","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27213437","Asiatic Acid Prevents the Deleterious Effects of Valproic Acid on Cognition and Hippocampal Cell Proliferation and Survival.","27213437",42]
["asiaticoside","asiaticoside","C004446","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23562630","Beneficial effects of asiaticoside on cognitive deficits in senescence-accelerated mice.","23562630",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10438276","Association of nonsteroidal anti-inflammatory drugs and aspirin with cognitive performance in middle-aged adults.","10438276",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12827329","Does aspirin protect against Alzheimer's dementia? A study in a Swedish population-based sample aged &gt; or =80 years.","12827329",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14975599","Histocompatibility antigens, aspirin use and cognitive performance in non-demented elderly subjects.","14975599",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8651230","Aspirin use and cognitive function in the elderly.","8651230",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"19112722","[The effect of ibuprofen and acetylsalicylic acid on cognitive impairment, total antioxidant power and isoprostane serum].","19112722",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20122039","Nonsteroidal anti-inflammatory drugs, aspirin, and cognitive function in the Baltimore longitudinal study of aging.","20122039",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22315948","Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion).","22315948",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"23364229","Cerebroprotective effect of preoperative dual antiplatelet therapy in patients undergoing coronary bypass surgery.","23364229",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23506847","Aspirin-triggered lipoxin A4 stimulates alternative activation of microglia and reduces Alzheimer disease-like pathology in mice.","23506847",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23709617","Aspirin-triggered resolvin D1 prevents surgery-induced cognitive decline.","23709617",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24699240","Acetylsalicylic acid and ascorbic acid combination improves cognition; via antioxidant effect or increased expression of NMDARs and nAChRs?","24699240",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25453448","Blood pressure control after stroke: too little, too late, or too soon to tell?","25453448",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25453457","Effects of long-term blood pressure lowering and dual antiplatelet treatment on cognitive function in patients with recent lacunar stroke: a secondary analysis from the SPS3 randomised trial.","25453457",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25898540","[Comparative experimental study of the influence of drugs that improve brain metabolism (angiogen, cytoflavin) on neuronal apoptosis and function of cerebral cortex during aging].","25898540",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"26757022","Comparing Cerebralcare Granule and aspirin for neurological dysfunction in acute stroke in real-life practice.","26757022",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2715564","Aspirin and MID. Notes of caution.","2715564",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27634976","ASPREE-NEURO study protocol: A randomized controlled trial to determine the effect of low-dose aspirin on cerebral microbleeds, white matter hyperintensities, cognition, and stroke in the healthy elderly.","27634976",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28425093","Low-Dose Aspirin Use and Cognitive Function in Older Age: A Systematic Review and Meta-analysis.","28425093",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"7105626","Central nervous system effects of aspirin.","7105626",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9069483","Is there any evidence for a protective effect of antithrombotic medication on cognitive function in men at risk of cardiovascular disease? Some preliminary findings.","9069483",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9725760","The influence of acetylsalicylic acid on cognitive processing: an event-related potentials study.","9725760",42]
["aspirin, succinic acid drug combination","aspirin, succinic acid drug combination","C469372","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25898540","[Comparative experimental study of the influence of drugs that improve brain metabolism (angiogen, cytoflavin) on neuronal apoptosis and function of cerebral cortex during aging].","25898540",42]
["Astemizole","Astemizole","D016589","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3122717","Lack of effects of astemizole on vestibular ocular reflex, motion sickness, and cognitive performance in man.","3122717",42]
["Astemizole","Astemizole","D016589","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"6120713","Performance studies with the H1-histamine receptor antagonists, astemizole and terfenadine.","6120713",42]
["Astemizole","Astemizole","D016589","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8368986","The effects of Benadryl and Hismanal on psychomotor performance and perceived performance.","8368986",42]
["Atenolol","Atenolol","D001262","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"106432","Effects of atenolol and propranolol on human performance and subjective feelings.","106432",42]
["Atenolol","Atenolol","D001262","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14578918","Influence of losartan and atenolol on memory function in very elderly hypertensive patients.","14578918",42]
["Atenolol","Atenolol","D001262","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1546860","Atenolol compared with nifedipine: effect on cognitive function and mood in elderly hypertensive patients.","1546860",42]
["Atenolol","Atenolol","D001262","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1564675","Cognitive effects of beta blockers.","1564675",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C643,B643)","v":"Atenolol"},"Atenolol","D001262","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J643,K643)","v":"Cognition"},"D003071","Cognition",0,1,1991,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q643,Q643)","v":"1777372"},"The effects of captopril vs atenolol on memory, information processing and mood: a double-blind crossover study.","1777372",42]
["Atenolol","Atenolol","D001262","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18519845","Cerebrovascular support for cognitive processing in hypertensive patients is altered by blood pressure treatment.","18519845",42]
["Atenolol","Atenolol","D001262","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2194029","Antihypertensive therapy and quality of life: a comparison of atenolol, captopril, enalapril and propranolol.","2194029",42]
["Atenolol","Atenolol","D001262","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2197376","Cognitive function in hypertensives treated with atenolol or propranolol.","2197376",42]
["Atenolol","Atenolol","D001262","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2225705","Quality of life among hypertensive patients with a diuretic background who are taking atenolol and enalapril.","2225705",42]
["Atenolol","Atenolol","D001262","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2719520","Beta-blockers and cognitive performance in older patients.","2719520",42]
["atipamezole","atipamezole","C050701","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10650154","The effects of a specific alpha(2)-adrenoceptor antagonist, atipamezole, on cognitive performance and brain neurochemistry in aged Fisher 344 rats.","10650154",42]
["atipamezole","atipamezole","C050701","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1350102","Atipamezole, an alpha 2 antagonist, stabilizes age-related high-voltage spindle and passive avoidance defects.","1350102",42]
["atipamezole","atipamezole","C050701","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9650845","Facilitation of cognitive functions by a specific alpha2-adrenoceptor antagonist, atipamezole.","9650845",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17644072","Atomoxetine improved response inhibition in adults with attention deficit/hyperactivity disorder.","17644072",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17934180","Medications do not necessarily normalize cognition in ADHD patients.","17934180",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18352838","Post-injury atomoxetine treatment improves cognition following experimental traumatic brain injury.","18352838",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18515446","Effects of atomoxetine on subjective and neurocognitive symptoms of nicotine abstinence.","18515446",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19700948","Atomoxetine augmentation of cholinesterase inhibitor therapy in patients with Alzheimer disease: 6-month, randomized, double-blind, placebo-controlled, parallel-trial study.","19700948",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20661027","Treatment of chronic akinetic mutism with atomoxetine: subtraction analysis of brain f-18 fluorodeoxyglucose positron emission tomographic images before and after medication: a case report.","20661027",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22338199","[Atomoxetine in ADHD: caution].","22338199",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22987022","Safety of atomoxetine in combination with intravenous cocaine in cocaine-experienced participants.","22987022",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"23912772","Dissociations between cognitive and motor effects of psychostimulants and atomoxetine in hyperactive DAT-KO mice.","23912772",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24206099","Atomoxetine improved attention in children and adolescents with attention-deficit/hyperactivity disorder and dyslexia in a 16 week, acute, randomized, double-blind trial.","24206099",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25285785","Could atomoxetine improve sluggish cognitive tempo symptoms?","25285785",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25896257","Effect of Atomoxetine on the Cognitive Functions in Treatment of Attention Deficit Hyperactivity Disorder in Children with Congenital Hypothyroidism: A Pilot Study.","25896257",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26218871","Effects of Atomoxetine and Osmotic Release Oral System-Methylphenidate on Executive Functions in Patients with Combined Type Attention-Deficit/Hyperactivity Disorder.","26218871",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26774596","Age-related changes in prefrontal norepinephrine transporter density: The basis for improved cognitive flexibility after low doses of atomoxetine in adolescent rats.","26774596",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27845858","Atomoxetine-Related Change in Sluggish Cognitive Tempo Is Partially Independent of Change in Attention-Deficit/Hyperactivity Disorder Inattentive Symptoms.","27845858",42]
["Atomoxetine Hydrochloride","Atomoxetine Hydrochloride","D000069445","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28716656","Atomoxetine in abstinent cocaine users: Cognitive, subjective and cardiovascular effects.","28716656",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12087035","Atorvastatin, diabetic dyslipidemia, and cognitive functioning.","12087035",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15974900","Atorvastatin therapy lowers circulating cholesterol but not free radical activity in advance of identifiable clinical benefit in the treatment of mild-to-moderate AD.","15974900",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16489473","Effects of atorvastatin on higher functions.","16489473",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16945213","Change in circulating C-reactive protein is not associated with atorvastatin treatment in Alzheimer's disease.","16945213",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17253908","Effect of atorvastatin on cognitive function in patients from the Lipid Lowering and Onset of Renal Disease (LORD) trial.","17253908",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18396246","Behavioral changes with paranoia in an elderly woman taking atorvastatin.","18396246",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18540154","Hippocampal volume change in the Alzheimer Disease Cholesterol-Lowering Treatment trial.","18540154",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20847439","Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs.","20847439",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21620819","Nitric oxide involvement in consolidation, but not retrieval phase of cognitive performance enhanced by atorvastatin in mice.","21620819",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22004509","Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease.","22004509",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22664571","Combination therapy of atorvastatin and amlodipine inhibits sympathetic nervous system activation and improves cognitive function in hypertensive rats.","22664571",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24040413","Chronic pravastatin but not atorvastatin treatment impairs cognitive function in two rodent models of learning and memory.","24040413",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24263322","The therapeutic potential of atorvastatin in a mouse model of postoperative cognitive decline.","24263322",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24657594","Long-term atorvastatin treatment leads to alterations in behavior, cognition, and hippocampal biochemistry.","24657594",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28750834","Protective effect of atorvastatin on d-galactose-induced aging model in mice.","28750834",42]
["Atrazine","Atrazine","D001280","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20624442","Early exposure to low doses of atrazine affects behavior in juvenile and adult CD1 mice.","20624442",42]
["Atrazine","Atrazine","D001280","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26440580","The effects of gestational and chronic atrazine exposure on motor behaviors and striatal dopamine in male Sprague-Dawley rats.","26440580",42]
["Atropine","Atropine","D001285","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1417646","Effects of 2 mg and 4 mg atropine sulfate on the performance of U.S. Army helicopter pilots.","1417646",42]
["Atropine","Atropine","D001285","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3549875","Effects of atropine and glycopyrrolate on cognitive function following anaesthesia and electroconvulsive therapy (ECT).","3549875",42]
["Atropine","Atropine","D001285","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3651279","Comparison of the effects of atropine and glycopyrrolate on cognitive function following general anaesthesia.","3651279",42]
["Atropine","Atropine","D001285","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"3882109","Comparison of the cognitive effects of premedication with hyoscine and atropine.","3882109",42]
["Atropine","Atropine","D001285","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"6806696","Effects of atropine sulfate and pralidoxime chloride on visual, physiological, performance, subjective, and cognitive variables in man: a review.","6806696",42]
["AVCRI104P4","AVCRI104P4","C000603053","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25732954","AVCRI104P3, a novel multitarget compound with cognition-enhancing and anxiolytic activities: studies in cognitively poor middle-aged mice.","25732954",42]
["AVE1625","AVE1625","C523652","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21181124","AVE1625, a cannabinoid CB1 receptor antagonist, as a co-treatment with antipsychotics for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side effects in rodents.","21181124",42]
["AVL3288","AVL3288","C000621157","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28196430","First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288.","28196430",42]
["Baclofen","Baclofen","D001418","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16361115","GABAB receptor: a site of therapeutic benefit.","16361115",42]
["Baclofen","Baclofen","D001418","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17691410","Relationship between intrathecal baclofen and the central nervous system.","17691410",42]
["Baclofen","Baclofen","D001418","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20521030","Effects of baclofen and mirtazapine on a laboratory model of marijuana withdrawal and relapse.","20521030",42]
["Baclofen","Baclofen","D001418","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22836369","Acute cocaine induced deficits in cognitive performance in rhesus macaque monkeys treated with baclofen.","22836369",42]
["Baclofen","Baclofen","D001418","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23268729","Effects of acute intrathecal baclofen in an animal model of TBI-induced spasticity, cognitive, and balance disabilities.","23268729",42]
["Baclofen","Baclofen","D001418","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24758898","Effects of intrahippocampal GABAB receptor antagonist treatment on the behavioral long-term potentiation and Y-maze learning performance.","24758898",42]
["Baclofen","Baclofen","D001418","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8851923","Effect of long term baclofen treatment on recognition memory and novelty detection.","8851923",42]
["Baclofen","Baclofen","D001418","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9512072","The effect of baclofen and AP-7 on selected behavior in rats.","9512072",42]
["bacoside A","bacoside A","C500175","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19944749","Bacopa monnieri and Bacoside-A for ameliorating epilepsy associated behavioral deficits.","19944749",42]
["bacoside A","bacoside A","C500175","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25965066","In Silico and In Vitro Analysis of Bacoside A Aglycones and Its Derivatives as the Constituents Responsible for the Cognitive Effects of Bacopa monnieri.","25965066",42]
["baicalein","baicalein","C006680","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18977207","Baicalein protects rat brain mitochondria against chronic cerebral hypoperfusion-induced oxidative damage.","18977207",42]
["baicalein","baicalein","C006680","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22891631","Baicalein attenuates impaired hippocampal neurogenesis and the neurocognitive deficits induced by γ-ray radiation.","22891631",42]
["baicalein","baicalein","C006680","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27233830","The flavonoid baicalein rescues synaptic plasticity and memory deficits in a mouse model of Alzheimer's disease.","27233830",42]
["baicalin","baicalin","C038044","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"23749289","Baicalin improves chronic corticosterone-induced learning and memory deficits via the enhancement of impaired hippocampal brain-derived neurotrophic factor and cAMP response element-binding protein expression in the rat.","23749289",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C707,B707)","v":"BAY 73-6691"},"BAY 73-6691","C507056","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J707,K707)","v":"Cognition"},"D003071","Cognition",0,1,2014,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q707,Q707)","v":"24746365"},"PDE9A inhibition rescues amyloid beta-induced deficits in synaptic plasticity and cognition.","24746365",42]
["BCG Vaccine","BCG Vaccine","D001500","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28183352","Combined effect of BCG vaccination and enriched environment promote neurogenesis and spatial cognition via a shift in meningeal macrophage M2 polarization.","28183352",42]
["befloxatone","befloxatone","C090014","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"10333984","Clinical pharmacology of befloxatone: a brief review.","10333984",42]
["befloxatone","befloxatone","C090014","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9728902","Cognitive performance in elderly subjects after a single dose of befloxatone, a new reversible selective monoamine oxidase A inhibitor.","9728902",42]
["Bencyclane","Bencyclane","D001537","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16447553","[Use of galidor in therapy of chronic brain ischemia].","16447553",42]
["Bendroflumethiazide","Bendroflumethiazide","D001539","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8636587","The effects of antihypertensive treatment on cognitive function: results from the HOPE study.","8636587",42]
["benphothiamine","benphothiamine","C013835","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20385653","Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice.","20385653",42]
["Benserazide","Benserazide","D001545","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15754768","[Madopar in the complex therapy of ischemic insult].","15754768",42]
["Benserazide","Benserazide","D001545","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19494158","L-dopa modulates functional connectivity in striatal cognitive and motor networks: a double-blind placebo-controlled study.","19494158",42]
["Benzene","Benzene","D001554","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24589379","Current understandings and perspectives on non-cancer health effects of benzene: a global concern.","24589379",42]
["Benzene","Benzene","D001554","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25881275","Exposure to fine particle matter, nitrogen dioxide and benzene during pregnancy and cognitive and psychomotor developments in children at 15 months of age.","25881275",42]
["Benzo(a)pyrene","Benzo(a)pyrene","D001564","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24584819","Subchronic oral administration of Benzo[a]pyrene impairs motor and cognitive behavior and modulates S100B levels and MAPKs in rats.","24584819",42]
["benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-","benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-","C496397","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15634000","4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H3 receptor antagonists potently enhance cognition and attention.","15634000",42]
["benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-","benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-","C496397","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15928819","Selective H3 receptor (H3R) blockade: broad efficacy in cognition and schizophrenia.","15928819",42]
["benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-","benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-","C496397","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23406742","Effects of the histamine H₃ receptor antagonist ABT-239 on cognition and nicotine-induced memory enhancement in mice.","23406742",42]
["benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-","benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-","C496397","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27291828","Donepezil, an acetylcholine esterase inhibitor, and ABT-239, a histamine H3 receptor antagonist/inverse agonist, require the integrity of brain histamine system to exert biochemical and procognitive effects in the mouse.","27291828",42]
["benzotriazole","benzotriazole","C012771","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26531152","Identification and optimisation of a series of tetrahydrobenzotriazoles as metabotropic glutamate receptor 5-selective positive allosteric modulators that improve performance in a preclinical model of cognition.","26531152",42]
["bepotastine besilate","bepotastine besilate","C511534","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19216705","Bepotastine besilate OD tablets suppress nasal symptoms caused by Japanese cedar pollen exposure in an artificial exposure chamber (OHIO Chamber).","19216705",42]
["Berberine","Berberine","D001599","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25079795","The IDO inhibitor coptisine ameliorates cognitive impairment in a mouse model of Alzheimer's disease.","25079795",42]
["bergamot oil","bergamot oil","C068336","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28591067","Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study.","28591067",42]
["beta Carotene","beta Carotene","D019207","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10075336","Effect of iron-, iodine-, and beta-carotene-fortified biscuits on the micronutrient status of primary school children: a randomized controlled trial.","10075336",42]
["beta Carotene","beta Carotene","D019207","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17998490","A randomized trial of beta carotene supplementation and cognitive function in men: the Physicians' Health Study II.","17998490",42]
["beta-carboline-3-carboxylic acid methyl ester","beta-carboline-3-carboxylic acid methyl ester","C036150","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1330204","Cognitive enhancing properties of beta-CCM infused into the nucleus basalis magnocellularis of the rat.","1330204",42]
["beta-hydroxyisovaleric acid","beta-hydroxyisovaleric acid","C004961","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"26896292","Effects of β-hydroxy-β-methyl butyrate on working memory and cognitive flexibility in an animal model of aging.","26896292",42]
["beta-hydroxyisovaleric acid","beta-hydroxyisovaleric acid","C004961","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27887984","Impact of β-hydroxy β-methylbutyrate (HMB) on age-related functional deficits in mice.","27887984",42]
["Betaine","Betaine","D001622","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17537289","The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.","17537289",42]
["Betaine","Betaine","D001622","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27502535","Effect of Afobazole and Betaine on Cognitive Disorders in the Offspring of Rats with Streptozotocin-Induced Diabetes and Their Relationship with DNA Damage.","27502535",42]
["beta-lapachone","beta-lapachone","C014638","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23071729","Beta-lapachone, a modulator of NAD metabolism, prevents health declines in aged mice.","23071729",42]
["Betamethasone","Betamethasone","D001623","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11531154","Multiple courses of antenatal betamethasone and cognitive development of mice offspring.","11531154",42]
["Betamethasone","Betamethasone","D001623","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16690949","Cognition- and anxiety-related behavior, synaptophysin and MAP2 immunoreactivity in the adult rat treated with a single course of antenatal betamethasone.","16690949",42]
["Betamethasone","Betamethasone","D001623","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23424017","Behavioural, educational and respiratory outcomes of antenatal betamethasone for term caesarean section (ASTECS trial).","23424017",42]
["Betamethasone","Betamethasone","D001623","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"7031582","Cognitive and psychosocial development of 4-year-old children whose mothers were treated antenatally with betamethasone.","7031582",42]
["Betamethasone","Betamethasone","D001623","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9125609","A placebo-controlled comparison between betamethasone and dexamethasone for fetal maturation: differences in neurobehavioral development of mice offspring.","9125609",42]
["Betaxolol","Betaxolol","D015784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16043136","The beta-1 adrenergic antagonist, betaxolol, improves working memory performance in rats and monkeys.","16043136",42]
["Betaxolol","Betaxolol","D015784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1723773","Impact of diagnosis and treatment of hypertension on quality of life: a double-blind, randomized, placebo-controlled, cross-over study of betaxolol.","1723773",42]
["Bethanechol","Bethanechol","D018723","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1676588","Stable bimodal response to cholinomimetic drugs in Alzheimer's disease. Brain mapping correlates.","1676588",42]
["Bethanechol","Bethanechol","D018723","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"2890709","Intracerebroventricular cholinergic drug administration in Alzheimer's disease: preliminary results of a double-blind study.","2890709",42]
["betulin","betulin","C002503","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26287580","Ameliorative effect of betulin from Betula platyphylla bark on scopolamine-induced amnesic mice.","26287580",42]
["betulinic acid","betulinic acid","C002070","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26287580","Ameliorative effect of betulin from Betula platyphylla bark on scopolamine-induced amnesic mice.","26287580",42]
["BIBN 99","BIBN 99","C079888","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7869110","Facilitation of acetylcholine release and cognitive performance by an M(2)-muscarinic receptor antagonist in aged memory-impaired.","7869110",42]
["bicalutamide","bicalutamide","C053541","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15247782","Re: The effects of combined androgen blockade on cognitive function during the first cycle of intermittent androgen suppression in patients with prostate cancer.","15247782",42]
["bifendate","bifendate","C465548","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"29268129","Development of tacrine-bifendate conjugates with improved cholinesterase inhibitory and pro-cognitive efficacy and reduced hepatotoxicity.","29268129",42]
["bilastine","bilastine","C445659","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27503042","Cognitive Performance Effects of Bilastine 20 mg During 6 Hours at 8000 ft Cabin Altitude.","27503042",42]
["Bilirubin","Bilirubin","D001663","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28617443","Bilirubin neurotoxicity is associated with proteasome inhibition.","28617443",42]
["binedaline","binedaline","C044680","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3088636","Human cognitive function following binedaline (50 mg and 100 mg) and imipramine (75 mg): results with a new battery on tests.","3088636",42]
["Biopterin","Biopterin","D001708","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20638313","Sapropterin therapy increases stability of blood phenylalanine levels in patients with BH4-responsive phenylketonuria (PKU).","20638313",42]
["Biopterin","Biopterin","D001708","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25232857","Long-term developmental progression in infants and young children taking sapropterin for phenylketonuria: a two-year analysis of safety and efficacy.","25232857",42]
["Biperiden","Biperiden","D001712","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20299191","Comparison of the efficacy and impact on cognition of glycopyrrolate and biperiden for clozapine-induced sialorrhea in schizophrenic patients: a randomized, double-blind, crossover study.","20299191",42]
["Biperiden","Biperiden","D001712","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23305134","Performance of conventional pigs and Göttingen miniature pigs in a spatial holeboard task: effects of the putative muscarinic cognition impairer Biperiden.","23305134",42]
["Biperiden","Biperiden","D001712","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25373869","Effects of anticholinergic challenge on psychopathology and cognition in drug-free patients with schizophrenia and healthy volunteers.","25373869",42]
["Biperiden","Biperiden","D001712","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28689687","The effect of the muscarinic M1 receptor antagonist biperiden on cognition in medication free subjects with psychosis.","28689687",42]
["bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)decandioate","bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)decandioate","C526136","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21821875","The radical scavenger IAC (bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) decantionate) decreases mortality, enhances cognitive functions in water maze and reduces amyloid plaque burden in hAβPP transgenic mice.","21821875",42]
["bis(9)-normeptazinol","bis(9)-normeptazinol","C583419","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23262302","Bis(9)-(-)-nor-meptazinol as a novel dual-binding AChEI potently ameliorates scopolamine-induced cognitive deficits in mice.","23262302",42]
["Bisoprolol","Bisoprolol","D017298","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10694836","Bisoprolol and nifedipine retard in elderly hypertensive patients: effect on quality of life.","10694836",42]
["bisphenol A","bisphenol A","C006780","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18048497","Bisphenol A prevents the synaptogenic response to testosterone in the brain of adult male rats.","18048497",42]
["bisphenol A","bisphenol A","C006780","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21971502","Dose-dependent behavioral disturbances after a single neonatal Bisphenol A dose.","21971502",42]
["bisphenol A","bisphenol A","C006780","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22484357","High dose bisphenol A impairs hippocampal neurogenesis in female mice across generations.","22484357",42]
["bisphenol A","bisphenol A","C006780","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25554518","Bisphenol-A exposure during adolescence leads to enduring alterations in cognition and dendritic spine density in adult male and female rats.","25554518",42]
["Biureas","Biureas","D001736","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24908956","[Parallel pharmacological correction of myocardial dysfunction, cognitive and psychopathological disordres in patients with congestive heart failure].","24908956",42]
["blonanserin","blonanserin","C079310","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23678596","[Blonanserin in the treatment of schizophrenia].","23678596",42]
["Blood Alcohol Content","Blood Alcohol Content","D000067401","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28034278","Proceeding of the 8th Alcohol Hangover Research Group Meeting.","28034278",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11465683","Use of antidepressants in treatment of comorbid diabetes mellitus and depression as well as in diabetic neuropathy.","11465683",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11512042","Glucose facilitation of cognitive performance in healthy young adults: examination of the influence of fast-duration, time of day and pre-consumption plasma glucose levels.","11512042",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15506876","Breakfasts that release glucose at different speeds interact with previous alcohol intake to influence cognition and mood before and after lunch.","15506876",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C771,B771)","v":"Blood Glucose"},"Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J771,K771)","v":"Cognition"},"D003071","Cognition",0,1,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q771,Q771)","v":"15982990"},"Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity.","15982990",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16401645","Effects of Panax ginseng, consumed with and without glucose, on blood glucose levels and cognitive performance during sustained 'mentally demanding' tasks.","16401645",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16443885","Improving metabolic control leads to better working memory in adults with type 2 diabetes.","16443885",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16886100","Glycemia and cognitive function in older adults using glucose-lowering drugs.","16886100",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"17851459","Effects of differences in postprandial glycaemia on cognitive functions in healthy middle-aged subjects.","17851459",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19650876","Insulin detemir causes increased symptom awareness during hypoglycaemia compared to human insulin.","19650876",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20140897","Manipulation of glycemic response with isomaltulose in a milk-based drink does not affect cognitive performance in healthy adults.","20140897",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20656408","Effects of intensified metabolic control on CNS function in type 2 diabetes.","20656408",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20709114","Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status.","20709114",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20920042","Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance.","20920042",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21958948","Intensive glucose lowering and cognition in type 2 diabetes.","21958948",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21958949","Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy.","21958949",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"21986189","The effect of high lactose-isomaltulose on cognitive performance of young children. A double blind cross-over design study.","21986189",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22017815","Breakfast glycaemic index and cognitive function in adolescent school children.","22017815",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22290574","Diabetes. Can tight glycemic control in diabetes benefit cognition?","22290574",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23244339","The effect of beverages varying in glycaemic load on postprandial glucose responses, appetite and cognition in 10-12-year-old school children.","23244339",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23789911","Response variability to glucose facilitation of cognitive enhancement.","23789911",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24899709","Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.","24899709",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24933430","Carbohydrate ingestion before and during soccer match play and blood glucose and lactate concentrations.","24933430",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25444682","Physiological and glycemic responses following acute ingestion of a popular functional drink in patients with type 1 diabetes.","25444682",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26922873","Amylin-mediated control of glycemia, energy balance, and cognition.","26922873",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"28068285","Vitamin K2 Improves Anxiety and Depression but not Cognition in Rats with Metabolic Syndrome: a Role of Blood Glucose?","28068285",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8531542","Effect of caffeine on recognition of and physiological responses to hypoglycaemia in insulin-dependent diabetes.","8531542",42]
["Blood Glucose","Blood Glucose","D001786","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8960830","Complications in IDDM are caused by elevated blood glucose level: the Stockholm Diabetes Intervention Study (SDIS) at 10-year follow up.","8960830",42]
["BMY 21502","BMY 21502","C064122","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1603891","Effects of oral BMY 21502 on Morris water task performance in 16-18 month old F-344 rats.","1603891",42]
["boswellic acid","boswellic acid","C054625","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21287538","Boswellia serrata acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial.","21287538",42]
["brexpiprazole","brexpiprazole","C000591922","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27784751","Switching from Inadequate Adjunctive or Combination Treatment Options to Brexpiprazole Adjunctive to Antidepressant: An Open-Label Study on the Effects on Depressive Symptoms and Cognitive and Physical Functioning.","27784751",42]
["brexpiprazole","brexpiprazole","C000591922","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27997809","Brexpiprazole for the treatment of schizophrenia.","27997809",42]
["Brimonidine Tartrate","Brimonidine Tartrate","D000068438","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1686301","Behavioral and receptor binding analysis of the alpha 2-adrenergic agonist, 5-bromo-6 [2-imidazoline-2-yl amino] quinoxaline (UK-14304): evidence for cognitive enhancement at an alpha 2-adrenoceptor subtype.","1686301",42]
["brivaracetam","brivaracetam","C482793","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20887370","Neurocognitive effects of brivaracetam, levetiracetam, and lorazepam.","20887370",42]
["Bromazepam","Bromazepam","D001960","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16100968","Analysis of the influence of bromazepam on cognitive performance through the visual evoked potential (P300).","16100968",42]
["Bromazepam","Bromazepam","D001960","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2565582","Placebo-controlled study on acute and subchronic effects of buspirone vs bromazepam utilizing psychomotor and cognitive assessments in healthy volunteers.","2565582",42]
["Bromocriptine","Bromocriptine","D001971","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11241875","Cortical effects of bromocriptine, a D-2 dopamine receptor agonist, in human subjects, revealed by fMRI.","11241875",42]
["Bromocriptine","Bromocriptine","D001971","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11990348","Attenuation of working memory and spatial acquisition deficits after a delayed and chronic bromocriptine treatment regimen in rats subjected to traumatic brain injury by controlled cortical impact.","11990348",42]
["Bromocriptine","Bromocriptine","D001971","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16403706","Bromocriptine in traumatic brain injury.","16403706",42]
["Bromocriptine","Bromocriptine","D001971","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"19189603","[The assessment of the mental state of patients during simultaneous treatment with psychotropic drugs, antipsychotics included, and bromocriptine].","19189603",42]
["Bromocriptine","Bromocriptine","D001971","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21611724","Human cognitive flexibility depends on dopamine D2 receptor signaling.","21611724",42]
["Bromocriptine","Bromocriptine","D001971","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23660437","Dissociable fronto-striatal effects of dopamine D2 receptor stimulation on cognitive versus motor flexibility.","23660437",42]
["Bromocriptine","Bromocriptine","D001971","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27676634","Dopaminergic contributions to working memory-related brain activation in postmenopausal women.","27676634",42]
["Bromocriptine","Bromocriptine","D001971","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9648550","Differential effect of a dopaminergic agonist on prefrontal function in traumatic brain injury patients.","9648550",42]
["bromotrifluoromethane","bromotrifluoromethane","C034013","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8449395","Toxicokinetics of inhaled bromotrifluoromethane (Halon 1301) in human subjects.","8449395",42]
["Brompheniramine","Brompheniramine","D001977","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"7104167","Differences in performance impairment due to brompheniramine maleate as a function of the sustained-release system.","7104167",42]
["brotizolam","brotizolam","C020960","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"7273596","Pharmacoelectroencephalographic study of brotizolam, a novel hypnotic.","7273596",42]
["bryostatin 1","bryostatin 1","C046785","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18469542","Analysis of long-term cognitive-enhancing effects of bryostatin-1 on the rabbit (Oryctolagus cuniculus) nictitating membrane response.","18469542",42]
["buflomedil","buflomedil","C010651","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6469443","Encephalotropic and psychotropic effects of intravenous buflomedil in the elderly: double-blind, placebo-controlled pharmaco-EEG and psychometric studies.","6469443",42]
["Bupivacaine","Bupivacaine","D002045","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18612876","Comparison of two patient-controlled analgesia techniques on neuropsychological functioning in the immediate postoperative period.","18612876",42]
["Bupivacaine","Bupivacaine","D002045","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9511167","Perinatal bupivacaine and infant behavior in rhesus monkeys.","9511167",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1376362","Acute effects of buprenorphine, hydromorphone and naloxone in methadone-maintained volunteers.","1376362",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16160628","Less impairment on one portion of a driving-relevant psychomotor battery in buprenorphine-maintained than in methadone-maintained patients: results of a randomized clinical trial.","16160628",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17565668","Methadone vs. buprenorphine/naloxone during early opioid substitution treatment: a naturalistic comparison of cognitive performance relative to healthy controls.","17565668",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17959980","Assessing cognitive and psychomotor performance under long-term treatment with transdermal buprenorphine in chronic noncancer pain patients.","17959980",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"19011441","Cognitive functioning during methadone and buprenorphine treatment: results of a randomized clinical trial.","19011441",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18598301","Pharmacokinetic-pharmacodynamic relationships of cognitive and psychomotor effects of intravenous buprenorphine infusion in human volunteers.","18598301",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20132119","Lack of clinically significant drug interactions between nevirapine and buprenorphine.","20132119",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21353749","The impact of long-term maintenance treatment with buprenorphine on complex psychomotor and cognitive function.","21353749",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21480011","Prenatal exposure to methadone and buprenorphine: a review of the potential effects on cognitive development.","21480011",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21851203","A comparison of cognitive function in patients under maintenance treatment with heroin, methadone, or buprenorphine and healthy controls: an open pilot study.","21851203",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21854644","Cognitive functioning in opioid-dependent patients treated with buprenorphine, methadone, and other psychoactive medications: stability and correlates.","21854644",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22386182","Buprenorphine maintenance therapy in opioid-addicted health care professionals returning to clinical practice: a hidden controversy.","22386182",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"2453895","Buprenorphine and naloxone alone and in combination in opioid-dependent humans.","2453895",42]
["Buprenorphine","Buprenorphine","D002047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25191915","Safety, tolerability, and clinical effect of low-dose buprenorphine for treatment-resistant depression in midlife and older adults.","25191915",42]
["Bupropion","Bupropion","D016642","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16079991","The effects of bupropion on cognitive functions in healthy subjects.","16079991",42]
["Bupropion","Bupropion","D016642","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17435629","Bupropion normalizes cognitive performance in patients with depression.","17435629",42]
["Bupropion","Bupropion","D016642","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"21942262","Effects of varenicline and bupropion on cognitive processes among nicotine-deprived smokers.","21942262",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C835,B835)","v":"Bupropion"},"Bupropion","D016642","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J835,K835)","v":"Cognition"},"D003071","Cognition",0,1,2012,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q835,Q835)","v":"22864270"},"Cognitive evaluation of bupropion sustained release in heavy tobacco smokers using event-related potentials.","22864270",42]
["Bupropion","Bupropion","D016642","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23052417","Psychological and physiological effects of bupropion compared to methylphenidate after prolonged administration in healthy volunteers (NCT00285155).","23052417",42]
["Bupropion","Bupropion","D016642","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25124683","The effect of bupropion XL and escitalopram on memory and functional outcomes in adults with major depressive disorder: results from a randomized controlled trial.","25124683",42]
["bushen huoxue","bushen huoxue","C527851","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24968700","Bushen Huoxue decoction improves cognitive decline in rats with cerebral hypoperfusion.","24968700",42]
["bushen yizhi","bushen yizhi","C000604209","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25482164","Alleviating effects of Bushen-Yizhi formula on ibotenic acid-induced cholinergic impairments in rat.","25482164",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1294894","Cognition and vigilance: differential effects of diazepam and buspirone on memory and psychomotor performance.","1294894",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1687731","The neurotransmitter basis of cognition: psychopharmacological activation studies using positron emission tomography.","1687731",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17329302","Lack of deleterious effects of buspirone on cognition in healthy male volunteers.","17329302",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9379784","Pharmacokinetics and CNS pharmacodynamics of the 5-HT1A agonist buspirone in humans following acute L-tryptophan depletion challenge.","9379784",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1984710","Effects of buspirone and alprazolam on the cognitive performance of normal elderly subjects.","1984710",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2565582","Placebo-controlled study on acute and subchronic effects of buspirone vs bromazepam utilizing psychomotor and cognitive assessments in healthy volunteers.","2565582",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26408868","Attenuation of methylphenidate-induced tolerance on cognition by buspirone co-administration.","26408868",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"6121766","Comparative effects of diazepam and buspirone on subjective feelings, psychological tests and the EEG.","6121766",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"6130075","Psychological effects of buspirone.","6130075",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9101342","Influence of diazepam and buspirone on human heart rate and the evoked cardiac response under varying cognitive load.","9101342",42]
["Buspirone","Buspirone","D002065","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9288408","Event-related potentials in a passive and active auditory condition: effects of diazepam and buspirone on slow wave positivity.","9288408",42]
["Butorphanol","Butorphanol","D002077","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8610901","The effects of transnasal butorphanol on mood and psychomotor functioning in healthy volunteers.","8610901",42]
["Butorphanol","Butorphanol","D002077","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26125754","Effects of intravenous analgesia with combined dezocine and butorphanol on postoperative cognitive function in elderly patients.","26125754",42]
["butyl acetate","butyl acetate","C006848","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10901114","Psychological test performance during experimental challenge to toluene and n-butyl acetate in cases of solvent-induced toxic encephalopathy.","10901114",42]
["cabergoline","cabergoline","C047047","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16768602","A mechanistic account of striatal dopamine function in human cognition: psychopharmacological studies with cabergoline and haloperidol.","16768602",42]
["Cadmium Chloride","Cadmium Chloride","D019256","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25288670","Exposure to As-, Cd-, and Pb-mixture induces Aβ, amyloidogenic APP processing and cognitive impairments via oxidative stress-dependent neuroinflammation in young rats.","25288670",42]
["caffeic acid","caffeic acid","C040048","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27430591","Effects of caffeic acid on learning deficits in a model of Alzheimer's disease.","27430591",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15678363","Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.","15678363",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15696321","Cognitive and psychomotor performance, mood, and pressor effects of caffeine after 4, 6 and 8 h caffeine abstinence.","15696321",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16388831","Role of familiarity on effects of caffeine- and glucose-containing soft drinks.","16388831",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10463319","The influences of age and caffeine on psychomotor and cognitive function.","10463319",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10823400","A naturalistic investigation of the effects of day-long consumption of tea, coffee and water on alertness, sleep onset and sleep quality.","10823400",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10857934","Influence of caffeine on the frequency and perception of hypoglycemia in free-living patients with type 1 diabetes.","10857934",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10947033","Slow-release caffeine: a new response to the effects of a limited sleep deprivation.","10947033",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11057520","Effects of low doses of caffeine on cognitive performance, mood and thirst in low and higher caffeine consumers.","11057520",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11140366","A taurine and caffeine-containing drink stimulates cognitive performance and well-being.","11140366",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11368507","The effects of ginseng, ephedrine, and caffeine on cognitive performance, mood and energy.","11368507",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11369156","Effects of caffeine as an adjuvant to morphine in advanced cancer patients. A randomized, double-blind, placebo-controlled, crossover study.","11369156",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11850090","The effects of a caffeine placebo and suggestion on blood pressure, heart rate, well-being and cognitive performance.","11850090",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11855129","[Effect of caffeine on cognitive function and psychophysiological status in man].","11855129",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11862356","Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine.","11862356",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11903856","Slow release caffeine and prolonged (64-h) continuous wakefulness: effects on vigilance and cognitive performance.","11903856",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11919004","Maximum cognitive performance and physiological time trend measurements after caffeine intake.","11919004",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12392588","Central and peripheral effects of sustained caffeine use: tolerance is incomplete.","12392588",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12397002","Coffee consumption and cognitive function among older adults.","12397002",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12424548","Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.","12424548",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12589526","Chronic treatment with caffeine blunts the hyperlocomotor but not cognitive effects of the N-methyl-D-aspartate receptor antagonist MK-801 in mice.","12589526",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12633594","Effects of mental workload and caffeine on catecholamines and blood pressure compared to performance variations.","12633594",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12653691","Dissociation of augmented physiological, hormonal and cognitive responses to hypoglycaemia with sustained caffeine use.","12653691",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12887140","Effects of tyrosine, phentermine, caffeine D-amphetamine, and placebo on cognitive and motor performance deficits during sleep deprivation.","12887140",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12917744","Memory functions and focussed attention in middle-aged and elderly subjects are unaffected by a low, acute dose of caffeine.","12917744",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12957237","The effects of habitual caffeine use on cognitive change: a longitudinal perspective.","12957237",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1365645","Effects of caffeine, time of day and user history on study-related performance.","1365645",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1369673","State-dependent learning with social drugs.","1369673",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14513920","Caffeine and central noradrenaline: effects on mood, cognitive performance, eye movements and cardiovascular function.","14513920",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14572506","Caffeine, fatigue, and cognition.","14572506",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1480627","Use and effects of food and drinks in relation to daily rhythms of mood and cognitive performance. Effects of caffeine, lunch and alcohol on human performance, mood and cardiovascular function.","1480627",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15164887","Low-dose repeated caffeine administration for circadian-phase-dependent performance degradation during extended wakefulness.","15164887",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15183925","A glucose-caffeine 'energy drink' ameliorates subjective and performance deficits during prolonged cognitive demand.","15183925",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15250767","Changes in regional cerebral blood volume in frontal cortex during mental work with and without caffeine intake: functional monitoring using near-infrared spectroscopy.","15250767",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15273831","Effects of caffeine on visual evoked potential (P300) and neuromotor performance.","15273831",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15325416","Caffeine strengthens action monitoring: evidence from the error-related negativity.","15325416",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15526987","Mood and cognitive performance effects of \"energy\" drink constituents: caffeine, glucose and carbonation.","15526987",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15549275","Cognitive and physiological effects of an \"energy drink\": an evaluation of the whole drink and of glucose, caffeine and herbal flavouring fractions.","15549275",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15627809","Recovery after prolonged sleep deprivation: residual effects of slow-release caffeine on recovery sleep, sleepiness and cognitive functions.","15627809",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15723227","The effect of caffeine on cognitive task performance and motor fatigue.","15723227",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15742338","The effects of caffeine and expectancy on attention and memory.","15742338",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15767842","Effect of subchronic caffeine treatment on MK-801-induced changes in locomotion, cognition and ataxia in mice.","15767842",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15887055","Effects of caffeine and caffeine withdrawal on mood and cognitive performance degraded by sleep restriction.","15887055",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C899,B899)","v":"Caffeine"},"Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J899,K899)","v":"Cognition"},"D003071","Cognition",0,1,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q899,Q899)","v":"15892913"},"Caffeine: implications for alertness in athletes.","15892913",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16007279","Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system.","16007279",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16043199","Effect of chronic caffeine intake on choice reaction time, mood, and visual vigilance.","16043199",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16120100","Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.","16120100",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16170233","Caffeine deprivation state modulates coffee consumption but not attentional bias for caffeine-related stimuli.","16170233",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16423144","Psychostimulant and other effects of caffeine in 9- to 11-year-old children.","16423144",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"16533867","A double-blind, placebo-controlled, multi-dose evaluation of the acute behavioural effects of guaraná in humans.","16533867",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16796223","The effects of caffeine, dextroamphetamine, and modafinil on humor appreciation during sleep deprivation.","16796223",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16845210","Ephedrine-caffeine mixture in wet-cold stress.","16845210",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16910172","Effects of caffeine in overnight-withdrawn consumers and non-consumers.","16910172",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17042248","Caffeinated tube food effect on pilot performance during a 9-hour, simulated nighttime U-2 mission.","17042248",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17050212","Cognitive performance during sustained wakefulness: A low dose of caffeine is equally effective as modafinil in alleviating the nocturnal decline.","17050212",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17051738","Evaluation of cognitive brain functions in caffeine users: a P3 evoked potential study.","17051738",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17136398","Differential responsiveness to caffeine and perceived effects of caffeine in moderate and high regular caffeine consumers.","17136398",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17199098","Effects of caffeine on electrophysiological and neuropsychological indices after sleep deprivation.","17199098",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17240784","Physiological and cognitive responses to caffeine during repeated, high-intensity exercise.","17240784",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17443132","Pharmacokinetic and pharmacodynamic interactions between zolpidem and caffeine.","17443132",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17509073","Caffeine restores regional brain activation in acute hypoglycaemia in healthy volunteers.","17509073",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17514640","Effects of repeated doses of caffeine on performance and alertness: new data and secondary analyses.","17514640",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17674233","Caffeine use by children: the quest for enhancement.","17674233",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17679672","The neuroprotective effects of caffeine: a prospective population study (the Three City Study).","17679672",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1780334","Effects of nicotine, caffeine, and their combination on locomotor activity in rats.","1780334",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17891480","Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.","17891480",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17891897","Caffeine effects on physical and cognitive performance during sustained operations.","17891897",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17905651","Caffeine effects on ERPs and performance in an auditory Go/NoGo task.","17905651",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17987647","Combined effects of smoking, coffee, and NSAIDs on Parkinson's disease risk.","17987647",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18006208","The effects of L-theanine, caffeine and their combination on cognition and mood.","18006208",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18254874","Psychological effects of dietary components of tea: caffeine and L-theanine.","18254874",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18266548","Enhanced mood and psychomotor performance by a caffeine-containing energy capsule in fatigued individuals.","18266548",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18322858","The effects of modafinil, caffeine, and dextroamphetamine on judgments of simple versus complex emotional expressions following sleep deprivation.","18322858",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19016251","Caffeine, cognitive failures and health in a non-working community sample.","19016251",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21693129","Chronic coffee and caffeine ingestion effects on the cognitive function and antioxidant system of rat brains.","21693129",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"7870897","Does caffeine intake enhance absolute levels of cognitive performance?","7870897",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18470842","[The effects of energy drinks on cognitive performance].","18470842",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18620014","Caffeine improves adult mice performance in the object recognition task and increases BDNF and TrkB independent on phospho-CREB immunocontent in the hippocampus.","18620014",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18641209","L-theanine and caffeine in combination affect human cognition as evidenced by oscillatory alpha-band activity and attention task performance.","18641209",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18681988","The combined effects of L-theanine and caffeine on cognitive performance and mood.","18681988",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18785355","Restoration of risk-propensity during sleep deprivation: caffeine, dextroamphetamine, and modafinil.","18785355",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18799996","Caffeine improves physical and cognitive performance during exhaustive exercise.","18799996",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"19146064","Energy drinks: the fads and the facts.","19146064",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"19230121","Caffeine: neuroprotective functions in cognition and Alzheimer's disease.","19230121",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19276624","The effect of recent consumption of caffeine-containing foodstuffs on neuropsychological tests in the elderly.","19276624",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19466633","Sensitivity to change in cognitive performance and mood measures of energy and fatigue in response to differing doses of caffeine or breakfast.","19466633",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19581723","Caffeine suppresses amyloid-beta levels in plasma and brain of Alzheimer's disease transgenic mice.","19581723",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19767804","The effect of a carbohydrate-caffeine sports drink on simulated golf performance.","19767804",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19827465","Caffeine enhances cognitive function and skill performance during simulated soccer activity.","19827465",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19922353","Sensitivity to change in cognitive performance and mood measures of energy and fatigue in response to morning caffeine alone or in combination with carbohydrate.","19922353",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19931288","Conditioned effects of caffeine on performance in humans.","19931288",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19995882","Caffeine consumption and cognitive function at age 70: the Lothian Birth Cohort 1936 study.","19995882",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20079786","L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness.","20079786",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20164566","Caffeine and adenosine.","20164566",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20182035","Is caffeine a cognitive enhancer?","20182035",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20182040","Caffeine and cognition in functional magnetic resonance imaging.","20182040",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20182052","Caffeine, cognition, and socioeconomic status.","20182052",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20182058","What knock-out animals tell us about the effects of caffeine.","20182058",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20521321","Effects of caffeine and glucose, alone and combined, on cognitive performance.","20521321",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20600342","Chronic caffeine treatment during prepubertal period confers long-term cognitive benefits in adult spontaneously hypertensive rats (SHR), an animal model of attention deficit hyperactivity disorder (ADHD).","20600342",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20629111","Randomized double-blind placebo-controlled crossover study of caffeine in patients with intermittent claudication.","20629111",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20808111","Cognitive slowing associated with elevated serum anticholinergic activity in older individuals is decreased by caffeine use.","20808111",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"21040626","The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness.","21040626",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21238877","Caffeinated alcoholic beverages: an emerging public health problem.","21238877",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21463650","Caffeine-induced physiological arousal accentuates global processing biases.","21463650",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21531247","Effects of caffeine on sleep and cognition.","21531247",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21570431","Herbal-caffeinated chewing gum, but not bubble gum, improves aspects of memory.","21570431",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C963,B963)","v":"Caffeine"},"Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J963,K963)","v":"Cognition"},"D003071","Cognition",0,1,2012,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q963,Q963)","v":"22453140"},"Sensitivity to cognitive effort mediates psychostimulant effects on a novel rodent cost/benefit decision-making task.","22453140",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22709816","Caffeine use among active duty US Army soldiers.","22709816",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22768218","What users think about the differences between caffeine and illicit/prescription stimulants for cognitive enhancement.","22768218",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22992376","Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.","22992376",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23006223","[Coffee can protect against disease].","23006223",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23015541","Caffeine, extraversion and working memory.","23015541",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23108937","Faster but not smarter: effects of caffeine and caffeine withdrawal on alertness and performance.","23108937",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23182694","A biomathematical model of the restoring effects of caffeine on cognitive performance during sleep deprivation.","23182694",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23313701","Energy drink ingredients. Contribution of caffeine and taurine to performance outcomes.","23313701",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23319129","Epidemiologic evidence of a relationship between tea, coffee, or caffeine consumption and cognitive decline.","23319129",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23344884","Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging.","23344884",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23363704","Role of state-dependent learning in the cognitive effects of caffeine in mice.","23363704",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23422357","Caffeine and cognitive decline in elderly women at high vascular risk.","23422357",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23528488","[Vasobral in the treatment of brain lesions: views of physicians and patients].","23528488",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23561485","Behavioural effects of compounds co-consumed in dietary forms of caffeinated plants.","23561485",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"23891504","Effects of caffeine and menthol on cognition and mood during simulated firefighting in the heat.","23891504",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24172303","Acute effects of tea consumption on attention and mood.","24172303",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24192642","The effect of acute caffeine ingestion on coincidence anticipation timing in younger and older adults.","24192642",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24282477","A comparison of blue light and caffeine effects on cognitive function and alertness in humans.","24282477",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24512799","The effects of caffeine ingestion on cortical areas: functional imaging study.","24512799",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24590053","Effects of blue light and caffeine on mood.","24590053",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24676319","Current evidence for the use of coffee and caffeine to prevent age-related cognitive decline and Alzheimer's disease.","24676319",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24732414","The effects of caffeine ingestion on the reaction time and short-term maximal performance after 36 h of sleep deprivation.","24732414",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24744319","Caffeine and alcohol intakes and overall nutrient adequacy are associated with longitudinal cognitive performance among U.S. adults.","24744319",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24892519","Caffeine and cognitive performance: persistent methodological challenges in caffeine research.","24892519",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24895603","Habitual coffee consumption enhances attention and vigilance in hemodialysis patients.","24895603",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24946991","Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis.","24946991",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25046515","Improvements in concentration, working memory and sustained attention following consumption of a natural citicoline-caffeine beverage.","25046515",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25047826","A comparison of the effects of transcranial direct current stimulation and caffeine on vigilance and cognitive performance during extended wakefulness.","25047826",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25051286","Caffeine and menopausal symptoms: what is the association?","25051286",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25072440","The Use of Caffeinated Substances by Surgeons for Cognitive Enhancement.","25072440",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25099503","The suitability of caffeinated drinks for children: a systematic review of randomised controlled trials, observational studies and expert panel guidelines.","25099503",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25196040","Effects of two doses of glucose and a caffeine-glucose combination on cognitive performance and mood during multi-tasking.","25196040",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25293543","Influence of energy drink ingredients on mood and cognitive performance.","25293543",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25355191","Exercise and sport performance with low doses of caffeine.","25355191",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25527035","Caffeine improves reaction time, vigilance and logical reasoning during extended periods with restricted opportunities for sleep.","25527035",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25614603","Effects of caffeine and maltodextrin mouth rinsing on P300, brain imaging, and cognitive performance.","25614603",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25689284","The effect of self-regulated caffeine use on cognition in young adults.","25689284",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25732217","Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review.","25732217",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25761837","A double-blind, placebo-controlled study evaluating the effects of caffeine and L-theanine both alone and in combination on cerebral blood flow, cognition and mood.","25761837",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25934571","Acute stress blocks the caffeine-induced enhancement of contextual memory retrieval in mice.","25934571",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26045170","Caffeine ingestion enhances perceptual responses during intermittent exercise in female team-game players.","26045170",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26156146","The Effects of Caffeine Use on Driving Safety Among Truck Drivers Who Are Habitual Caffeine Users.","26156146",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26395526","Effects of concurrent caffeine and mobile phone exposure on local target probability processing in the human brain.","26395526",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26585526","Maternal Caffeine Intake During Pregnancy and Child Cognition and Behavior at 4 and 7 Years of Age.","26585526",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26610558","Cognitive Performance and Mood Following Ingestion of a Theacrine-Containing Dietary Supplement, Caffeine, or Placebo by Young Men and Women.","26610558",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26614014","Effects of caffeine intake and smoking on neurocognition in schizophrenia.","26614014",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26621326","Acute personalized habitual caffeine doses improve attention and have selective effects when considering the fractionation of executive functions.","26621326",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26686275","Performance pressure and caffeine both affect cognitive performance, but likely through independent mechanisms.","26686275",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26932511","The influence of espresso coffee on neurocognitive function in HIV-infected patients.","26932511",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27002645","The Effect of Prior Caffeine Consumption on Neuropsychological Test Performance: A Placebo-Controlled Study.","27002645",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"27124986","Stimulant Use by Medical Students.","27124986",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"27124987","Response from Authors.","27124987",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2726998","High doses of caffeine impair performance of a numerical version of the Stroop task in men.","2726998",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27453554","The impact of caffeine use across the lifespan on cognitive performance in elderly women.","27453554",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28044450","Caffeine and theanine exert opposite effects on attention under emotional arousal.","28044450",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28054436","Low dose of caffeine enhances the efficacy of antidepressants in major depressive disorder and the underlying neural substrates.","28054436",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28182503","Do Glucose and Caffeine Nasal Sprays Influence Exercise and/or Cognitive Performance?","28182503",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28969341","Caffeine to optimize cognitive function for military mission-readiness: a systematic review and recommendations for the field.","28969341",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28983971","Effects of caffeinated alcoholic beverages with low alcohol and high caffeine content on cognitive and motor functions.","28983971",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"29072170","Caffeine intake and abstract reasoning among 1374 unselected men and women from general population. Role of the -163C&gt;A polymorphism of CYP1A2 gene.","29072170",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3064045","Can caffeine antagonize alcohol-induced performance decrements in humans?","3064045",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3517081","Pharmacokinetic and pharmacodynamic interactions between caffeine and diazepam.","3517081",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3602037","Interactions of diazepam and caffeine: behavioral and subjective dose effects in humans.","3602037",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1027,B1027)","v":"Caffeine"},"Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1027,K1027)","v":"Cognition"},"D003071","Cognition",0,1,1985,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1027,Q1027)","v":"3834354"},"The effects of caffeine on psychological functioning.","3834354",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1974,"4438536","Drugs and placebos: effects of caffeine on cognitive performance.","4438536",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1983,"6374311","Caffeine and theophylline counteract diazepam effects in man.","6374311",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1980,"6445402","The interactive effect of personality, time of day, and caffeine: a test of the arousal model.","6445402",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1980,"6445403","Personality, time of day, and caffeine: some theoretical and conceptual problems in Revelle et al.","6445403",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1980,"6445404","Individual differences in diurnal rhythms and multiple activation states: a reply to M. W. Eysenck and Folkard.","6445404",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6500006","The effects of caffeine on physiological functions and mental performance.","6500006",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"7299385","Behavioral and cognitive effects of caffeine in boys and adult males.","7299385",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"7457638","Acute effects of caffeine in normal prepubertal boys.","7457638",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7675951","Effects of caffeine on cognition and mood without caffeine abstinence.","7675951",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8026448","The use of prophylactic naps and caffeine to maintain performance during a continuous operation.","8026448",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8172489","Effects of breakfast and caffeine on cognitive performance, mood and cardiovascular functioning.","8172489",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8172490","Effects of evening meals and caffeine on cognitive performance, mood and cardiovascular functioning.","8172490",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8531542","Effect of caffeine on recognition of and physiological responses to hypoglycaemia in insulin-dependent diabetes.","8531542",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8603222","Behavioral and cognitive effects of methylxanthines. A meta-analysis of theophylline and caffeine.","8603222",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8743589","Effects of caffeine, practice, and mode of presentation on Stroop task performance.","8743589",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8848531","Caffeine attenuates scopolamine-induced memory impairment in humans.","8848531",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9264092","Effects of brief caffeinated-beverage deprivation on mood, symptoms, and psychomotor performance.","9264092",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9566812","Quadratic dose-response relationship between caffeine (1,3,7-trimethylxanthine) and EEG correlation dimension.","9566812",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9586865","Regular caffeine consumption: a balance of adverse and beneficial effects for mood and psychomotor performance.","9586865",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9784078","The effects of black tea and other beverages on aspects of cognition and psychomotor performance.","9784078",42]
["Caffeine","Caffeine","D002110","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9862410","The effects of a low dose of caffeine on cognitive performance.","9862410",42]
["Calcitriol","Calcitriol","D002117","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17258168","Is vitamin D important for preserving cognition? A positive correlation of serum 25-hydroxyvitamin D concentration with cognitive function.","17258168",42]
["Calcium Carbonate","Calcium Carbonate","D002119","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23176129","Calcium and vitamin D supplementation and cognitive impairment in the women's health initiative.","23176129",42]
["Calcium Carbonate","Calcium Carbonate","D002119","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23772744","Vitamin D and cognition: recommendations for future trials.","23772744",42]
["Calcium Carbonate","Calcium Carbonate","D002119","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23772745","Response to Annweiler and Beauchet.","23772745",42]
["Camphor","Camphor","D002164","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18929475","The effect of Camphor-Crataegus berry extract combination on blood pressure and mental functions in chronic hypotension--a randomized placebo controlled double blind design.","18929475",42]
["Camphor","Camphor","D002164","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19560327","D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study.","19560327",42]
["candesartan","candesartan","C081643","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12714861","The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial.","12714861",42]
["candesartan","candesartan","C081643","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16109319","Effect of baseline cognitive function and antihypertensive treatment on cognitive and cardiovascular outcomes: Study on COgnition and Prognosis in the Elderly (SCOPE).","16109319",42]
["candesartan","candesartan","C081643","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16601563","The Study on COgnition and Prognosis in the Elderly (SCOPE)--recent analyses.","16601563",42]
["candesartan","candesartan","C081643","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16754269","Findings and implications of the Study on COgnition and Prognosis in the Elderly (SCOPE) - a review.","16754269",42]
["candesartan","candesartan","C081643","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18458219","Candesartan and cognitive decline in older patients with hypertension: a substudy of the SCOPE trial.","18458219",42]
["candesartan","candesartan","C081643","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22412114","Effect of antihypertensive therapy on cognitive function in early executive cognitive impairment: a double-blind randomized clinical trial.","22412114",42]
["candesartan","candesartan","C081643","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22890474","Candesartan prevents impairment of recall caused by repeated stress in rats.","22890474",42]
["candesartan","candesartan","C081643","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23350899","Antihypertensive therapy and cerebral hemodynamics in executive mild cognitive impairment: results of a pilot randomized clinical trial.","23350899",42]
["candesartan cilexetil","candesartan cilexetil","C077793","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10595696","Study on COgnition and Prognosis in the Elderly (SCOPE).","10595696",42]
["candesartan cilexetil","candesartan cilexetil","C077793","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11059636","Reducing cardiovascular morbidity and mortality in the elderly.","11059636",42]
["canertinib dihydrochloride","canertinib dihydrochloride","C072383","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9815700","Neurotoxicity of CI-980, a novel mitotic inhibitor.","9815700",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"115049","The effect of cannabidiol, alone and in combination with ethanol, on human performance.","115049",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"120541","Interaction of cannabidiol and alcohol in humans.","120541",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17884351","Acute effects of Delta9-tetrahydrocannabinol and standardized cannabis extract on the auditory evoked mismatch negativity.","17884351",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19596476","Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation.","19596476",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19627647","Neuroimaging in cannabis use: a systematic review of the literature.","19627647",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20128798","Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation.","20128798",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20339735","Performance of schizophrenic patients in the Stroop Color Word Test and electrodermal responsiveness after acute administration of cannabidiol (CBD).","20339735",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21182490","Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice.","21182490",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23085269","Cannabidiol reduces host immune response and prevents cognitive impairments in Wistar rats submitted to pneumococcal meningitis.","23085269",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23550724","Cannabidiol attenuates deficits of visuospatial associative memory induced by Δ(9) tetrahydrocannabinol.","23550724",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25595981","Cannabidiol increases survival and promotes rescue of cognitive function in a murine model of cerebral malaria.","25595981",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26890764","Cannabinoid Receptor 2 Participates in Amyloid-β Processing in a Mouse Model of Alzheimer's Disease but Plays a Minor Role in the Therapeutic Properties of a Cannabis-Based Medicine.","26890764",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27471947","The therapeutic potential of the phytocannabinoid cannabidiol for Alzheimer's disease.","27471947",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27690502","Acute and chronic effects of cannabidiol on Δ⁹-tetrahydrocannabinol (Δ⁹-THC)-induced disruption in stop signal task performance.","27690502",42]
["Cannabidiol","Cannabidiol","D002185","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28501518","Cannabidiol in medical marijuana: Research vistas and potential opportunities.","28501518",42]
["Capsaicin","Capsaicin","D002211","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28112976","Effects of cannabinoid and vanilloid receptor agonists and their interaction on learning and memory in rats.","28112976",42]
["Capsaicin","Capsaicin","D002211","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9620514","Analgesic and cognitive effects of intravenous ketamine-alfentanil combinations versus either drug alone after intradermal capsaicin in normal subjects.","9620514",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10385842","Carbamazepine withdrawal in children with previous symptomatic partial epilepsy: effects on neuropsychologic function.","10385842",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10487192","Differential cognitive effects of carbamazepine and gabapentin.","10487192",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10593548","Cognitive and behavioral effects of carbamazepine in children: data from benign rolandic epilepsy.","10593548",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10999556","A multicenter, randomized clinical study to evaluate the effect on cognitive function of topiramate compared with valproate as add-on therapy to carbamazepine in patients with partial-onset seizures.","10999556",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11074185","Tiagabine versus phenytoin and carbamazepine as add-on therapies: effects on abilities, adjustment, and mood.","11074185",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11342682","Differential cognitive and behavioral effects of carbamazepine and lamotrigine.","11342682",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11422333","Comparative cognitive effects of carbamazepine and gabapentin in healthy senior adults.","11422333",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11772334","Oxcarbazepine.","11772334",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1091,B1091)","v":"Carbamazepine"},"Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1091,K1091)","v":"Cognition"},"D003071","Cognition",0,1,2002,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1091,Q1091)","v":"12027908"},"Effects of gabapentin and carbamazepine on the EEG and cognition in healthy volunteers.","12027908",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1345559","[The effect of monotherapy on concentration of selected blood serum hormones and upon cognitive function of children with epilepsy].","1345559",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1396535","Cognitive effects of oxcarbazepine and phenytoin monotherapy in newly diagnosed epilepsy: one year follow-up.","1396535",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1471883","Psychological effects of sodium valproate and carbamazepine in epilepsy.","1471883",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14981399","Chronic prenatal exposure to carbamazepine and behavior effects on mice offspring.","14981399",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15203438","Treatment of alcohol withdrawal: chlormethiazole vs. carbamazepine and the effect on memory performance--a pilot study.","15203438",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15367726","Clinical, cognitive, and neurophysiologic correlates of short-term treatment with carbamazepine, oxcarbazepine, and levetiracetam in healthy volunteers.","15367726",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1547763","Effect of acute doses of controlled-release carbamazepine on clinical, psychomotor, electrophysiological, and cognitive parameters of brain function.","1547763",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15582838","Effects of oxcarbazepine and phenytoin on the EEG and cognition in healthy volunteers.","15582838",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16886974","Comparison of the cognitive effects of tiagabine and carbamazepine as monotherapy in newly diagnosed adult patients with partial epilepsy: pooled analysis of two long-term, randomized, follow-up studies.","16886974",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16924022","Effects of oxcarbazepine on cognitive function in children and adolescents with partial seizures.","16924022",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19111629","The cognitive and psychomotor effects of remacemide and carbamazepine in newly diagnosed epilepsy.","19111629",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1922792","Comparative cognitive effects of carbamazepine and phenytoin in healthy adults.","1922792",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1998458","Neurobehavioral effects of phenytoin, carbamazepine, and valproic acid: implications for use in traumatic brain injury.","1998458",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20002063","Effect of carbamazepine and lamotrigine on cognitive function and oxidative stress in brain during chemical epileptogenesis in rats.","20002063",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20149756","Antiepileptic drugs and quality of life in the elderly: results from a randomized double-blind trial of carbamazepine and lamotrigine in patients with onset of epilepsy in old age.","20149756",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20436439","[Comparative effectiveness of mood stabilizers in the complex therapy of bulimia nervosa].","20436439",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20573223","LICAVAL: combination therapy in acute and maintenance treatment of bipolar disorder.","20573223",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20708576","Effect of eslicarbazepine acetate and oxcarbazepine on cognition and psychomotor function in healthy volunteers.","20708576",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21067945","Cognitive and behavioral effects of lamotrigine and carbamazepine monotherapy in patients with newly diagnosed or untreated partial epilepsy.","21067945",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2119303","Effects of removal of phenytoin, carbamazepine, and valproate on cognitive function.","2119303",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22521904","Effects of lamotrigine on cognition and behavior compared to carbamazepine as monotherapy for children with partial epilepsy.","22521904",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27426469","Immediate and delayed treatment with gabapentin, carbamazepine and CNQX have almost similar impact on cognitive functions and behavior in the lithium-pilocarpine model in rats.","27426469",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27517350","Randomized double-blind comparison of cognitive and EEG effects of lacosamide and carbamazepine.","27517350",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"2994882","Carbamazepine: a neuropsychological and psychiatric profile.","2994882",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3148638","Lack of differential cognitive effects of lithium and carbamazepine in bipolar affective disorder.","3148638",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3280564","Carbamazepine and mood: evidence from patients with seizure disorders.","3280564",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3395263","Carbamazepine and phenytoin. Comparison of cognitive effects in epileptic patients during monotherapy and withdrawal.","3395263",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3653052","Controlled release carbamazepine: cognitive side effects in patients with epilepsy.","3653052",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3956451","A comparative study of the cognitive effects of phenytoin and carbamazepine in new referrals with epilepsy.","3956451",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1977,"558553","Carbamazepine as an anticonvulsant in children.","558553",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7489696","Comparing the cognitive effects of phenytoin and carbamazepine in long-term monotherapy: a two-year follow-up.","7489696",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7497946","[Side effects of phenytoin and carbamazepine on cognitive functioning].","7497946",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7509419","Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy.","7509419",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7670773","Phenytoin and carbamazepine: differential effects on cognitive function.","7670773",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7896910","Alpha rhythm slowing during initiation of carbamazepine therapy: implications for future cognitive performance.","7896910",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8018037","Neurobehavioral effects of phenytoin and carbamazepine in patients recovering from brain trauma: a comparative study.","8018037",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8269913","Carbamazepine and phenytoin in epilepsies refractory to barbiturates: efficacy, toxicity and mental function.","8269913",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8288212","[The effects of phenytoin and carbamazepine on the cognitive function of epileptic patients].","8288212",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8414057","Anticonvulsant withdrawal.","8414057",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8422849","Effects of carbamazepine and phenytoin on EEG and memory in healthy adults.","8422849",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8423909","Withdrawal of antiepileptic medication in children--effects on cognitive function: The Multicenter Holmfrid Study.","8423909",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8783377","The effects of antiepileptic drugs on cognition in normal volunteers.","8783377",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9626926","Pharmacokinetics and cognitive effects of carbamazepine formulations with different dissolution rates.","9626926",42]
["carbamide peroxide","carbamide peroxide","C009096","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15601603","Cortical effects of quetiapine in first-episode schizophrenia: a preliminary functional magnetic resonance imaging study.","15601603",42]
["Carbidopa","Carbidopa","D002230","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1976,"1273240","Intravenous l-DOPA plus carbidopa in depressed patients: average evoked response, learning, and behavioral changes.","1273240",42]
["Carbidopa","Carbidopa","D002230","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24654442","[Clinical studies with levodopa/carbidopa intestinal gel].","24654442",42]
["Carbidopa","Carbidopa","D002230","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9171930","The combined use of amantadine and l-dopa/carbidopa in the treatment of chronic brain injury.","9171930",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10934900","Acute changes in carbon dioxide levels alter the electroencephalogram without affecting cognitive function.","10934900",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18354390","Carbon dioxide-induced emotion and respiratory symptoms in healthy volunteers.","18354390",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20540443","Extending submarine crew survival by reducing CO2 production with quickly reversible sedation.","20540443",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21395683","The effect of carbon dioxide insufflation on cognitive function during cardiac surgery.","21395683",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21547765","Effects of 7.5% CO(2) inhalation on allocation of spatial attention to facial cues of emotional expression.","21547765",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22594137","Assessment of cognitive function while on low-dose propranolol: implications for usage by survivors in a disabled submarine.","22594137",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26273786","High indoor CO2 concentrations in an office environment increases the transcutaneous CO2 level and sleepiness during cognitive work.","26273786",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26502459","Associations of Cognitive Function Scores with Carbon Dioxide, Ventilation, and Volatile Organic Compound Exposures in Office Workers: A Controlled Exposure Study of Green and Conventional Office Environments.","26502459",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"29195572","Carbon Dioxide Insufflation During Cardiac Surgery: A Meta-analysis of Randomized Controlled Trials.","29195572",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"3929433","Effects of toluene inhalation on behavior and expired carbon dioxide in macaque monkeys.","3929433",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1972,"5074717","Cognitive function after hypocapnic hyperventilation.","5074717",42]
["Carbon Dioxide","Carbon Dioxide","D002245","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"6804625","Cognitive factors in carbon dioxide therapy.","6804625",42]
["Carbon Disulfide","Carbon Disulfide","D002246","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1983,"6683828","A behavioral examination of workers exposed to carbon disulfide.","6683828",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10479472","Effects of early postnatal exposure to low concentrations of carbon monoxide on cognitive functions in rats.","10479472",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14635216","Mild carbon monoxide exposure and auditory function in the developing rat.","14635216",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22897968","Effects of hydrogen-rich saline on rats with acute carbon monoxide poisoning.","22897968",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1155,B1155)","v":"Carbon Monoxide"},"Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1155,K1155)","v":"Cognition"},"D003071","Cognition",0,1,2013,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1155,Q1155)","v":"23334141"},"Detection of gray matter damage using brain MRI and SPECT in carbon monoxide intoxication: a comparison study with neuropsychological correlation.","23334141",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25845300","Allopurinol reduces severity of delayed neurologic sequelae in experimental carbon monoxide toxicity in rats.","25845300",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26052629","Dexamethasone therapy for preventing delayed encephalopathy after carbon monoxide poisoning.","26052629",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26164025","Therapeutic Effects of Hydrogen Sulfide in Treating Delayed Encephalopathy After Acute Carbon Monoxide Poisoning.","26164025",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2730486","Interactive effects of heat, physical work, and CO exposure on metabolism and cognitive task performance.","2730486",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3240213","Interactive effects of physical work and carbon monoxide on cognitive task performance.","3240213",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"388013","Carbon monoxide poisoning: the injury and its treatment.","388013",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1974,"4618381","The effects of low concentration of carbon monoxide in man.","4618381",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1976,"778353","Proceedings: The effect of carbon monoxide on humans.","778353",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8143232","Does endogenous zinc protoporphyrin modulate carbon monoxide formation from heme? Implications for long-term potentiation, memory, and cognitive function.","8143232",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9626776","Neuropsychological impairment from acute low-level exposure to carbon monoxide.","9626776",42]
["cariprazine","cariprazine","C533287","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26655189","Effects of cariprazine, a novel antipsychotic, on cognitive deficit and negative symptoms in a rodent model of schizophrenia symptomatology.","26655189",42]
["Carisoprodol","Carisoprodol","D002328","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21884720","Characterizing the subjective and psychomotor effects of carisoprodol in healthy volunteers.","21884720",42]
["Carmustine","Carmustine","D002330","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24037801","Preservation of neurocognitive function and local control of 1 to 3 brain metastases treated with surgery and carmustine wafers.","24037801",42]
["Carnitine","Carnitine","D002331","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14760514","The influence on cognition of the interactions between lecithin, carnitine and carbohydrate.","14760514",42]
["Carnitine","Carnitine","D002331","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"18065594","L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial.","18065594",42]
["Carnitine","Carnitine","D002331","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2140973","[Effects of L-acetylcarnitine on mental deterioration in the aged: initial results].","2140973",42]
["Carnitine","Carnitine","D002331","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2201659","Acetyl-L-carnitine in the treatment of mildly demented elderly patients.","2201659",42]
["Carnitine","Carnitine","D002331","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22254121","Metabolic agents that enhance ATP can improve cognitive functioning: a review of the evidence for glucose, oxygen, pyruvate, creatine, and L-carnitine.","22254121",42]
["Carnitine","Carnitine","D002331","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24005823","L-carnitine exposure and mitochondrial function in human neuronal cells.","24005823",42]
["Carnitine","Carnitine","D002331","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27241631","l-Carnitine improves cognitive and renal functions in a rat model of chronic kidney disease.","27241631",42]
["Carnitine","Carnitine","D002331","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28349514","L-carnitine for cognitive enhancement in people without cognitive impairment.","28349514",42]
["carvacrol","carvacrol","C073316","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22470103","Cognitive-enhancing activity of thymol and carvacrol in two rat models of dementia.","22470103",42]
["carvedilol","carvedilol","C043211","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17391169","beta-blocker use and diabetes symptom score: results from the GEMINI study.","17391169",42]
["catalpol","catalpol","C078040","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18573305","d-galactose administration induces memory loss and energy metabolism disturbance in mice: protective effects of catalpol.","18573305",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16549472","Long-term administration of green tea catechins improves spatial cognition learning ability in rats.","16549472",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18276944","Green tea catechin polyphenols attenuate behavioral and oxidative responses to intermittent hypoxia.","18276944",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19656855","Green tea (-)-epigallocatechin-3-gallate inhibits beta-amyloid-induced cognitive dysfunction through modification of secretase activity via inhibition of ERK and NF-kappaB pathways in mice.","19656855",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21821105","Epigallocatechin gallate ameliorates behavioral and biochemical deficits in rat model of load-induced chronic fatigue syndrome.","21821105",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22127270","Acute neurocognitive effects of epigallocatechin gallate (EGCG).","22127270",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22389082","Epigallocatechin gallate, cerebral blood flow parameters, cognitive performance and mood in healthy humans: a double-blind, placebo-controlled, crossover investigation.","22389082",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22521706","Effects of epigallocatechin-3-gallate on pentylenetetrazole-induced kindling, cognitive impairment and oxidative stress in rats.","22521706",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22964138","Green tea (-)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia.","22964138",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23001939","Cognitive enhancement and neuroprotection by catechin-rich oil palm leaf extract supplement.","23001939",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24039182","Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.","24039182",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24561313","Flavocoxid, dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, exhibits neuroprotection in rat model of ischaemic stroke.","24561313",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24946991","Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis.","24946991",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25150118","Oligonol improves memory and cognition under an amyloid β(25-35)-induced Alzheimer's mouse model.","25150118",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27457036","Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome.","27457036",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28478033","Epigallocatechin-3-gallate (EGCG) consumption in the Ts65Dn model of Down syndrome fails to improve behavioral deficits and is detrimental to skeletal phenotypes.","28478033",42]
["Catechin","Catechin","D002392","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28818411","Long-term supplementation with EGCG and beta-alanine decreases mortality but does not affect cognitive or muscle function in aged mice.","28818411",42]
["cathinone","cathinone","C023665","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26070760","\"Natural Amphetamine\" Khat: A Cultural Tradition or a Drug of Abuse?","26070760",42]
["Ceftriaxone","Ceftriaxone","D002443","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26296668","Synergistic effects of ceftriaxone and erythropoietin on neuronal and behavioral deficits in an MPTP-induced animal model of Parkinson's disease dementia.","26296668",42]
["Ceftriaxone","Ceftriaxone","D002443","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28487222","Neuroprotective effects of ceftriaxone treatment on cognitive and neuronal deficits in a rat model of accelerated senescence.","28487222",42]
["Celecoxib","Celecoxib","D000068579","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15549344","Clinical effects of COX-2 inhibitors on cognition in schizophrenia.","15549344",42]
["Celecoxib","Celecoxib","D000068579","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18474729","Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.","18474729",42]
["Celecoxib","Celecoxib","D000068579","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18776882","Anti-inflammatory drugs fall short in Alzheimer's disease.","18776882",42]
["Celecoxib","Celecoxib","D000068579","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"21560159","Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: findings from the randomized controlled Alzheimer's Disease Anti-inflammatory Prevention Trial.","21560159",42]
["Celecoxib","Celecoxib","D000068579","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25022541","Follow-up evaluation of cognitive function in the randomized Alzheimer's Disease Anti-inflammatory Prevention Trial and its Follow-up Study.","25022541",42]
["Celecoxib","Celecoxib","D000068579","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26398269","Cyclooxygenase I and II inhibitors distinctly enhance hippocampal- and cortex-dependent cognitive functions in mice.","26398269",42]
["Centella asiatica extract","Centella asiatica extract","C526146","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22074576","Exploring the role of \"Brahmi\" (Bocopa monnieri and Centella asiatica) in brain function and therapy.","22074576",42]
["Centella asiatica extract","Centella asiatica extract","C526146","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26785167","Centella asiatica modulates antioxidant and mitochondrial pathways and improves cognitive function in mice.","26785167",42]
["Cereboost","Cereboost","C000615592","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25778987","Improved working memory performance following administration of a single dose of American ginseng (Panax quinquefolius L.) to healthy middle-age adults.","25778987",42]
["Cereboost","Cereboost","C000615592","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27112419","Cereboost™, an American ginseng extract, improves cognitive function via up-regulation of choline acetyltransferase expression and neuroprotection.","27112419",42]
["cerebralcare preparation","cerebralcare preparation","C553222","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"26757022","Comparing Cerebralcare Granule and aspirin for neurological dysfunction in acute stroke in real-life practice.","26757022",42]
["Cetirizine","Cetirizine","D017332","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11317473","An investigation into the effects of cetirizine on cognitive function and psychomotor performance in healthy volunteers.","11317473",42]
["Cetirizine","Cetirizine","D017332","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16389668","Evaluation of the cognitive, psychomotor and pharmacokinetic profiles of rupatadine, hydroxyzine and cetirizine, in combination with alcohol, in healthy volunteers.","16389668",42]
["Cetirizine","Cetirizine","D017332","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11922397","The acute and sub-chronic effects of levocetirizine, cetirizine, loratadine, promethazine and placebo on cognitive function, psychomotor performance, and weal and flare.","11922397",42]
["Cetirizine","Cetirizine","D017332","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12100225","Lack of effect of single and repeated doses of levocetirizine, a new antihistamine drug, on cognitive and psychomotor functions in healthy volunteers.","12100225",42]
["Cetirizine","Cetirizine","D017332","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12149503","Long-term evaluation of the impact of the h1-receptor antagonist cetirizine on the behavioral, cognitive, and psychomotor development of very young children with atopic dermatitis.","12149503",42]
["Cetirizine","Cetirizine","D017332","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20735428","Histamine H1 receptor antagonist cetirizine impairs working memory processing speed, but not episodic memory.","20735428",42]
["Cetirizine","Cetirizine","D017332","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24303975","Evaluation of the antihistamine effects of olopatadine and levocetirizine during a 24-h period: a double-blind, randomized, cross-over, placebo-controlled comparison in skin responses induced by histamine iontophoresis.","24303975",42]
["Cetirizine","Cetirizine","D017332","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9491258","Central effects of the H1-antihistamine, cetirizine.","9491258",42]
["cevimeline","cevimeline","C059240","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10978492","Effects of muscarinic and adrenergic agonism on auditory P300 in the macaque.","10978492",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1219,B1219)","v":"cevimeline"},"cevimeline","C059240","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1219,K1219)","v":"Cognition"},"D003071","Cognition",0,1,1992,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1219,Q1219)","v":"1506863"},"Comparison of the effects of selective and nonselective muscarinic agonists on cognition and thermoregulation in primates.","1506863",42]
["CGP 11952","CGP 11952","C044664","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3438463","CGP 11.952: an experimental benzodiazepine derivative. Effects on cognitive functioning in patients with epilepsy.","3438463",42]
["CGP 35348","CGP 35348","C066430","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28596118","Neuroprotective role of GABAB receptor modulation against streptozotocin-induced behavioral and biochemical abnormalities in rats.","28596118",42]
["CGP 35348","CGP 35348","C066430","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8390321","Reversal of scopolamine-induced amnesia by the GABAB receptor antagonist CGP 35348 in the mouse.","8390321",42]
["Chenodeoxycholic Acid","Chenodeoxycholic Acid","D002635","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24529221","Long-term follow-up on the effect of combined therapy of bile acids and statins in the treatment of cerebrotendinous xanthomatosis: a case report.","24529221",42]
["Chewing Gum","Chewing Gum","D002638","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15458808","Role of glucose in chewing gum-related facilitation of cognitive function.","15458808",42]
["Chewing Gum","Chewing Gum","D002638","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20630497","Chew on this: No support for facilitating effects of gum on spatial task performance.","20630497",42]
["Chewing Gum","Chewing Gum","D002638","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21570431","Herbal-caffeinated chewing gum, but not bubble gum, improves aspects of memory.","21570431",42]
["Chitosan","Chitosan","D048271","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26601759","Chitosan oligosaccharides alleviate cognitive deficits in an amyloid-β1-42-induced rat model of Alzheimer's disease.","26601759",42]
["chlorbipram","chlorbipram","C000589512","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24113523","Chlorbipram: a novel PDE4 inhibitor with improved safety as a potential antidepressant and cognitive enhancer.","24113523",42]
["Chlordan","Chlordan","D002706","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9076301","Chlordane as a neurotoxin in humans.","9076301",42]
["Chlordecone","Chlordecone","D007631","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22910562","Cognitive, visual, and motor development of 7-month-old Guadeloupean infants exposed to chlordecone.","22910562",42]
["Chlordiazepoxide","Chlordiazepoxide","D002707","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15765256","Effects of CRF1 receptor antagonists and benzodiazepines in the Morris water maze and delayed non-matching to position tests.","15765256",42]
["Chlordiazepoxide","Chlordiazepoxide","D002707","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1780421","Sabeluzole improves social recognition and antagonizes chlordiazepoxide's effect on habituation in the rat.","1780421",42]
["Chlordiazepoxide","Chlordiazepoxide","D002707","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1973,"4589809","Antianxiety drugs and human performance.","4589809",42]
["Chlordiazepoxide","Chlordiazepoxide","D002707","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1978,"630860","Cognitive and psychophysiologic response to doxepin and chlordiazepoxide.","630860",42]
["Chlordiazepoxide","Chlordiazepoxide","D002707","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6329901","Effects of valium and librium on human psychomotor and cognitive functions.","6329901",42]
["Chlormethiazole","Chlormethiazole","D002719","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15203438","Treatment of alcohol withdrawal: chlormethiazole vs. carbamazepine and the effect on memory performance--a pilot study.","15203438",42]
["Chlormethiazole","Chlormethiazole","D002719","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1977,"320851","The relief of restlessness in the elderly.","320851",42]
["Chlormethiazole","Chlormethiazole","D002719","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1978,"727060","The effect of an hypnotic with a short half-life on hangover effect in old patients.","727060",42]
["Chlorodiphenyl (54% Chlorine)","Chlorodiphenyl (54% Chlorine)","D020111","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11543949","Perinatal exposure to polychlorinated biphenyls Aroclor 1016 or 1254 did not alter brain catecholamines nor delayed alternation performance in Long-Evans rats.","11543949",42]
["Chlorodiphenyl (54% Chlorine)","Chlorodiphenyl (54% Chlorine)","D020111","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12075116","Neurobehavioral assessments of rats perinatally exposed to a commercial mixture of polychlorinated biphenyls.","12075116",42]
["Chlorogenic Acid","Chlorogenic Acid","D002726","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"21773723","Does coffee enriched with chlorogenic acids improve mood and cognition after acute administration in healthy elderly? A pilot study.","21773723",42]
["Chlorogenic Acid","Chlorogenic Acid","D002726","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24349389","A randomised placebo-controlled trial to differentiate the acute cognitive and mood effects of chlorogenic acid from decaffeinated coffee.","24349389",42]
["Chlorpheniramine","Chlorpheniramine","D002744","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11874393","Differential cognitive effects of ebastine and (+)-chlorpheniramine in healthy subjects: correlation between cognitive impairment and plasma drug concentration.","11874393",42]
["Chlorpheniramine","Chlorpheniramine","D002744","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14696020","Comparative study of acute effects of single doses of fexofenadine, olopatadine, d-chlorpheniramine and placebo on psychomotor function in healthy volunteers.","14696020",42]
["Chlorpheniramine","Chlorpheniramine","D002744","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16834833","Allergy medication in Japanese volunteers: treatment effect of single doses on nocturnal sleep architecture and next day residual effects.","16834833",42]
["Chlorpheniramine","Chlorpheniramine","D002744","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"18626140","Chlorpheniramine and ephedrine in combination for motion sickness.","18626140",42]
["Chlorpheniramine","Chlorpheniramine","D002744","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2258042","Effect of allergy medication on children's reading comprehension.","2258042",42]
["Chlorpheniramine","Chlorpheniramine","D002744","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2570799","Differential cognitive effects of terfenadine and chlorpheniramine.","2570799",42]
["Chlorpheniramine","Chlorpheniramine","D002744","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1978,"351355","The interaction between ethanol and antihistamines. 1: Dexchlorpheniramine.","351355",42]
["Chlorpheniramine","Chlorpheniramine","D002744","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8201490","Benefit/risk ratio of the antihistamines (H1-receptor antagonists) terfenadine and chlorpheniramine in children.","8201490",42]
["Chlorpromazine","Chlorpromazine","D002746","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10759338","Dosage of conventional neuroleptic medication and subjective cognitive functioning in schizophrenia.","10759338",42]
["Chlorpromazine","Chlorpromazine","D002746","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11448094","The differential effects of chlorpromazine and haloperidol on latent inhibition in healthy volunteers.","11448094",42]
["Chlorpromazine","Chlorpromazine","D002746","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1523284","Effects of chlorpromazine and lorazepam on explicit memory, repetition priming and cognitive skill learning in healthy volunteers.","1523284",42]
["Chlorpromazine","Chlorpromazine","D002746","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1978,"210476","Paradoxical effects in sleep and performance of two doses of chlorpromazine.","210476",42]
["Chlorpromazine","Chlorpromazine","D002746","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1977,"326215","Phenothiazine effects on psychological and psychophysiological dysfunction in chronic schizophrenics.","326215",42]
["Chlorpromazine","Chlorpromazine","D002746","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1968,"4884170","Psychiatric diagnosis and a typology of clinical drug effects.","4884170",42]
["Chlorpromazine","Chlorpromazine","D002746","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1978,"722623","The effect of chlorpromazine upon psychophysiological, endocrine and information processing measures in schizophrenia.","722623",42]
["Chlorpromazine","Chlorpromazine","D002746","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8412415","Clinical-pharmacological study with the two isomers (d-, l-) of fenfluramine and its comparison with chlorpromazine and d-amphetamine: psychometric and psychophysiological evaluation.","8412415",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10429680","Determination of the reference dose for chlorpyrifos: proceedings of an expert panel.","10429680",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10758353","Chlorpyrifos: lack of cognitive effects in adult Long-Evans rats.","10758353",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11006355","Lack of selective developmental neurotoxicity in rat pups from dams treated by gavage with chlorpyrifos.","11006355",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11274874","Comparing cognitive and screening tests for neurotoxicity. Effects of acute chlorpyrifos on visual signal detection and a neurobehavioral test battery in rats.","11274874",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11446824","Cognitive function and cholinergic neurochemistry in weanling rats exposed to chlorpyrifos.","11446824",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17116700","Impact of prenatal chlorpyrifos exposure on neurodevelopment in the first 3 years of life among inner-city children.","17116700",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21669222","Cognitive and histological disturbances after chlorpyrifos exposure and chronic Aβ(1-42) infusions in Wistar rats.","21669222",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20554631","Ameliorative effects of vitamin C on short-term sensorimotor and cognitive changes induced by acute chlorpyrifos exposure in Wistar rats.","20554631",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22547821","Brain anomalies in children exposed prenatally to a common organophosphate pesticide.","22547821",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22824009","Does the home environment and the sex of the child modify the adverse effects of prenatal exposure to chlorpyrifos on child working memory?","22824009",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25592617","Prenatal nicotine changes the response to postnatal chlorpyrifos: Interactions targeting serotonergic synaptic function and cognition.","25592617",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25704171","Prenatal exposure of guinea pigs to the organophosphorus pesticide chlorpyrifos disrupts the structural and functional integrity of the brain.","25704171",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7522308","Time-dependent effects of acute chlorpyrifos administration on spatial delayed alternation and cholinergic neurochemistry in weanling rats.","7522308",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7531775","Assessment of the neurotoxic potential of chlorpyrifos relative to other organophosphorus compounds: a critical review of the literature.","7531775",42]
["Chlorpyrifos","Chlorpyrifos","D004390","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"7689099","Behavioral and neurochemical effects of acute chlorpyrifos in rats: tolerance to prolonged inhibition of cholinesterase.","7689099",42]
["Cholecalciferol","Cholecalciferol","D002762","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20586644","NT-020, a natural therapeutic approach to optimize spatial memory performance and increase neural progenitor cell proliferation and decrease inflammation in the aged rat.","20586644",42]
["Cholecalciferol","Cholecalciferol","D002762","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23176129","Calcium and vitamin D supplementation and cognitive impairment in the women's health initiative.","23176129",42]
["Cholecalciferol","Cholecalciferol","D002762","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23772744","Vitamin D and cognition: recommendations for future trials.","23772744",42]
["Cholecalciferol","Cholecalciferol","D002762","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23772745","Response to Annweiler and Beauchet.","23772745",42]
["Cholecalciferol","Cholecalciferol","D002762","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28167237","Does high dose vitamin D supplementation enhance cognition?: A randomized trial in healthy adults.","28167237",42]
["Cholecalciferol","Cholecalciferol","D002762","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28818511","Vitamin D enhances antiepileptic and cognitive effects of lamotrigine in pentylenetetrazole-kindled rats.","28818511",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10806282","Effects of lovastatin on cognitive function and psychological well-being.","10806282",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11448316","Statins and dementia.","11448316",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11565814","Effects of lovastatin and pravastatin on cognitive function in military aircrew.","11565814",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1283,B1283)","v":"Cholesterol"},"Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1283,K1283)","v":"Cognition"},"D003071","Cognition",0,1,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1283,Q1283)","v":"15974900"},"Atorvastatin therapy lowers circulating cholesterol but not free radical activity in advance of identifiable clinical benefit in the treatment of mild-to-moderate AD.","15974900",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16860552","Pharmacological actions of Thespesia populnea relevant to Alzheimer's disease.","16860552",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16945213","Change in circulating C-reactive protein is not associated with atorvastatin treatment in Alzheimer's disease.","16945213",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17233704","Total cholesterol levels and the risk of mild cognitive impairment and Alzheimer's disease.","17233704",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17253908","Effect of atorvastatin on cognitive function in patients from the Lipid Lowering and Onset of Renal Disease (LORD) trial.","17253908",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17522597","Model-based drug development.","17522597",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18540154","Hippocampal volume change in the Alzheimer Disease Cholesterol-Lowering Treatment trial.","18540154",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18846153","[Forgetful because of statins?].","18846153",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19344763","Oral apolipoprotein A-I mimetic peptide improves cognitive function and reduces amyloid burden in a mouse model of Alzheimer's disease.","19344763",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19370582","Statins for the prevention of dementia.","19370582",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19653027","Pravastatin and cognitive function in the elderly. Results of the PROSPER study.","19653027",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20847439","Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs.","20847439",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22664571","Combination therapy of atorvastatin and amlodipine inhibits sympathetic nervous system activation and improves cognitive function in hypertensive rats.","22664571",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24108067","Simvastatin treatment highlights a new role for the isoprenoid/cholesterol biosynthetic pathway in the modulation of emotional reactivity and cognitive performance in rats.","24108067",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24626726","Behavioural and cognitive effects of simvastatin dose used in stimulation of bone regeneration in rats.","24626726",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26589247","Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice.","26589247",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26727124","Statins for the prevention of dementia.","26727124",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28256666","Neuroprotective effects of phytosterol esters against high cholesterol-induced cognitive deficits in aged rat.","28256666",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28813214","Cognitive Function in a Randomized Trial of Evolocumab.","28813214",42]
["Cholesterol","Cholesterol","D002784","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7619678","Effects of treatment with simvastatin and pravastatin on cognitive function in patients with hypercholesterolaemia.","7619678",42]
["Cholesterol, Dietary","Cholesterol, Dietary","D002791","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18222653","Behavioral effects of dietary cholesterol in rats tested in experimental models of mild stress and cognition tasks.","18222653",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11481240","Memory impairment and cholinergic dysfunction by centrally administered Abeta and carboxyl-terminal fragment of Alzheimer's APP in mice.","11481240",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11842883","Diet restriction in mice causes a decrease in hippocampal choline uptake and muscarinic receptors that is restored by administration of tyrosine: interaction between cholinergic and adrenergic receptors influencing cognitive function.","11842883",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12502178","Choline ingestion does not modify physical or cognitive performance.","12502178",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12737935","Combined uridine and choline administration improves cognitive deficits in spontaneously hypertensive rats.","12737935",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12948004","Potential effects of supplementation with amino acids, choline or sialic acid on cognitive development in young infants.","12948004",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15611726","Choline transporters, cholinergic transmission and cognition.","15611726",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1596741","Transplantation of fetal cholinergic neurons into the hippocampus attenuates the cognitive and neurochemical deficits induced by AF64A.","1596741",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16504295","An overview of evidence for a causal relationship between dietary availability of choline during development and cognitive function in offspring.","16504295",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18400712","Choline concentrations in human maternal and cord blood and intelligence at 5 y of age.","18400712",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19215057","Cholinergic dysfunction in fragile X syndrome and potential intervention: a preliminary 1H MRS study.","19215057",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19303260","Proton magnetic resonance spectroscopy of late-life major depressive disorder.","19303260",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"1982696","Global in vivo replacement of choline by N-aminodeanol. Testing a hypothesis about progressive degenerative dementia: II. Physiological and behavioral effects.","1982696",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21775074","Age and sex effects levels of choline compounds in the anterior cingulate cortex of adolescent methamphetamine users.","21775074",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22071706","The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort.","22071706",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23325325","Effects of davunetide on N-acetylaspartate and choline in dorsolateral prefrontal cortex in patients with schizophrenia.","23325325",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23425631","Choline intake during pregnancy and child cognition at age 7 years.","23425631",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23536015","Elevated prefrontal myo-inositol and choline following breast cancer chemotherapy.","23536015",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24130988","Optimization of choline administration regimen for correction of cognitive functions in rats after brain injury.","24130988",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25681529","Neurocognitive effects of acute choline supplementation in low, medium and high performer healthy volunteers.","25681529",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26540073","Synergistic Effects of Human Milk Nutrients in the Support of Infant Recognition Memory: An Observational Study.","26540073",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27806977","Randomized, double-blind, placebo-controlled clinical trial of choline supplementation in school-aged children with fetal alcohol spectrum disorders.","27806977",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27871887","A silk peptide fraction restores cognitive function in AF64A-induced Alzheimer disease model rats by increasing expression of choline acetyltransferase gene.","27871887",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28642069","Chronic choline supplementation improves cognitive and motor performance via modulating oxidative and neurochemical status in rats.","28642069",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28788094","Neuroprotective Actions of Dietary Choline.","28788094",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"2987637","The effects of various cognition-enhancing drugs on in vitro rat hippocampal synaptosomal sodium dependent high affinity choline uptake.","2987637",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3110830","Effect of combined or separate administration of piracetam and choline on learning and memory in the rat.","3110830",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"7312098","Choline chloride fails to improve cognition of Alzheimer's disease.","7312098",42]
["Choline","Choline","D002794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8871956","Effects of chronic infusion of nerve growth factor (NGF) in AF64A-lesioned rats.","8871956",42]
["choto-san","choto-san","C120250","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16398922","A Chinese herbal medicine, choto-san, improves cognitive function and activities of daily living of patients with dementia: a double-blind, randomized, placebo-controlled study.","16398922",42]
["choto-san","choto-san","C120250","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23082896","Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: possible involvement of cholinergic and VEGF/PDGF mechanisms in the brain.","23082896",42]
["choto-san","choto-san","C120250","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23883485","Kampo formulations, chotosan, and yokukansan, for dementia therapy: existing clinical and preclinical evidence.","23883485",42]
["choto-san","choto-san","C120250","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26994819","Chotosan improves Aβ1-42-induced cognitive impairment and neuroinflammatory and apoptotic responses through the inhibition of TLR-4/NF-κB signaling in mice.","26994819",42]
["Chunghyuldan","Chunghyuldan","C499382","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24820962","Neuroprotective effect of Chunghyuldan from amyloid beta oligomer induced neuroinflammation in vitro and in vivo.","24820962",42]
["Chyavanprash","Chyavanprash","C518324","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20738179","Beneficial effect of chyawanprash on cognitive function in aged mice.","20738179",42]
["cicaprost","cicaprost","C043867","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"2829267","Human studies on the benzodiazepine receptor antagonist beta-carboline ZK 93,426: preliminary observations on psychotropic activity.","2829267",42]
["Cilazapril","Cilazapril","D017315","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17180313","Cognitive function and the emotional state of stroke patients on antihypertensive therapy.","17180313",42]
["Cilazapril","Cilazapril","D017315","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7700071","Effects of cilazapril and nitrendipine on blood pressure, mood, sleep, and cognitive function in elderly hypertensive patients: an Italian multicenter study.","7700071",42]
["cilostazol","cilostazol","C045645","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20035772","Cilostazol improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus.","20035772",42]
["cilostazol","cilostazol","C045645","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22672107","Effects of cilostazol on cognition and regional cerebral blood flow in patients with Alzheimer's disease and cerebrovascular disease: a pilot study.","22672107",42]
["cilostazol","cilostazol","C045645","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"25707423","Cilostazol improves cognitive function in patients with mild cognitive impairment: a retrospective analysis.","25707423",42]
["cilostazol","cilostazol","C045645","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28231822","Cilostazol as an add-on therapy for patients with Alzheimer's disease in Taiwan: a case control study.","28231822",42]
["Cimetidine","Cimetidine","D002927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10322244","Examination of the cognitive effects of cimetidine in normal elderly volunteers.","10322244",42]
["Cimetidine","Cimetidine","D002927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"7138754","Influence of cimetidine on oral diazepam elimination with measurement of subsequent cognitive change.","7138754",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1347,B1347)","v":"Cimetidine"},"Cimetidine","D002927","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1347,K1347)","v":"Cognition"},"D003071","Cognition",0,1,1993,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1347,Q1347)","v":"8494127"},"Interaction of H2-receptor antagonists and benzodiazepine sedation. A double-blind placebo-controlled investigation of the effects of cimetidine and ranitidine on recovery after intravenous midazolam.","8494127",42]
["cinepazide","cinepazide","C026896","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27990002","Cinepazide Maleate Improves Cognitive Function and Protects Hippocampal Neurons in Diabetic Rats with Chronic Cerebral Hypoperfusion.","27990002",42]
["cinnamic aldehyde","cinnamic aldehyde","C012843","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27387400","Reversal of diabetes-induced behavioral and neurochemical deficits by cinnamaldehyde.","27387400",42]
["Cinnarizine","Cinnarizine","D002936","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19672226","[Use of omaron in patients with post-stroke cognitive disorders].","19672226",42]
["Cinnarizine","Cinnarizine","D002936","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3114803","Promethazine, scopolamine and cinnarizine: comparative time course of psychological performance effects.","3114803",42]
["ciproxifan","ciproxifan","C115705","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21073971","Ciproxifan, an H3 receptor antagonist, alleviates hyperactivity and cognitive deficits in the APP Tg2576 mouse model of Alzheimer's disease.","21073971",42]
["ciproxifan","ciproxifan","C115705","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"23975035","Single dose of H3 receptor antagonist--ciproxifan--abolishes negative effects of chronic stress on cognitive processes in rats.","23975035",42]
["cirazoline","cirazoline","C014282","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9264070","The alpha-1 adrenergic agonist, cirazoline, impairs spatial working memory performance in aged monkeys.","9264070",42]
["Cisplatin","Cisplatin","D002945","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20708851","Cognitive functioning after radiotherapy or chemoradiotherapy for head-and-neck cancer.","20708851",42]
["Cisplatin","Cisplatin","D002945","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26001812","Impairment of cognitive function by chemotherapy: association with the disruption of phase-locking and synchronization in anterior cingulate cortex.","26001812",42]
["Cisplatin","Cisplatin","D002945","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27492363","Edaravone alleviates cisplatin-induced neurobehavioral deficits via modulation of oxidative stress and inflammatory mediators in the rat hippocampus.","27492363",42]
["Cisplatin","Cisplatin","D002945","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27845242","Neo-adjuvant chemotherapy with cisplatin induces low expression of NMDA receptors and postoperative cognitive impairment.","27845242",42]
["Cisplatin","Cisplatin","D002945","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27908784","Cisplatin-induced mitochondrial dysfunction is associated with impaired cognitive function in rats.","27908784",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11263719","Serotonin 5-HT2A receptor binding in platelets from patients with Alzheimer's disease or vascular dementia.","11263719",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12185407","Acute administration of citalopram facilitates memory consolidation in healthy volunteers.","12185407",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15107656","Citalopram in the treatment of dysthymic disorder.","15107656",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15229059","Increased positive versus negative affective perception and memory in healthy volunteers following selective serotonin and norepinephrine reuptake inhibition.","15229059",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1529737","A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia.","1529737",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15377738","Citalopram treatment of depression in Parkinson's disease: the impact on anxiety, disability, and cognition.","15377738",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15876902","The effect of citalopram adjunctive treatment added to atypical antipsychotic medications for cognitive performance in patients with schizophrenia.","15876902",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16525858","The effects of escitalopram on working memory and brain activity in healthy adults during performance of the n-back task.","16525858",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17679567","SSRI effects on pyschomotor performance: assessment of citalopram and escitalopram on normal subjects.","17679567",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17697395","Antidepressive therapy with escitalopram improves mood, cognitive symptoms, and identity memory for angry faces in elderly depressed patients.","17697395",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19695841","Acute citalopram administration may disrupt contextual information processing in healthy males.","19695841",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19916207","Change in cognitive functioning following acute antidepressant treatment in late-life depression.","19916207",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20104071","Improving depression and enhancing resilience in family dementia caregivers: a pilot randomized placebo-controlled trial of escitalopram.","20104071",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21208417","International Study to Predict Optimized Treatment for Depression (iSPOT-D), a randomized clinical trial: rationale and protocol.","21208417",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21352389","Sleep and cognition at baseline and the effects of REM sleep diminution after 1 week of antidepressive treatment in patients with depression.","21352389",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21358389","Complementary use of tai chi chih augments escitalopram treatment of geriatric depression:  a randomized controlled trial.","21358389",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21786537","Effects of citalopram on cognitive performance in passive avoidance, elevated plus-maze and three-panel runway tasks in naïve rats.","21786537",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"21958534","Central glucocorticoid receptor-mediated effects of the antidepressant, citalopram, in humans: a study using EEG and cognitive testing.","21958534",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22008191","5-HT2A receptors in the orbitofrontal cortex facilitate reversal learning and contribute to the beneficial cognitive effects of chronic citalopram treatment in rats.","22008191",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22459724","The effect of selective serotonin reuptake inhibitors in healthy first-degree relatives of patients with major depressive disorder - an experimental medicine blinded controlled trial.","22459724",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22981666","Escitalopram improves memory deficits induced by maternal separation in the rat.","22981666",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24375941","Results of the citalopram to enhance cognition in Huntington disease trial.","24375941",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24503278","The effects of acute pharmacological stimulation of the 5-HT, NA and DA systems on the cognitive judgement bias of rats in the ambiguous-cue interpretation paradigm.","24503278",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24525660","Improvement in subjective and objective neurocognitive functions in patients with major depressive disorder: a 12-week, multicenter, randomized trial of tianeptine versus escitalopram, the CAMPION study.","24525660",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24549548","Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial.","24549548",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25124683","The effect of bupropion XL and escitalopram on memory and functional outcomes in adults with major depressive disorder: results from a randomized controlled trial.","25124683",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26142691","Influence of anxiety symptoms on improvement of neurocognitive functions in patients with major depressive disorder: A 12-week, multicenter, randomized trial of tianeptine versus escitalopram, the CAMPION study.","26142691",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26169527","Cognitive control, reward-related decision making and outcomes of late-life depression treated with an antidepressant.","26169527",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26342888","Cognitive and psychomotor effects of three months of escitalopram treatment in elderly patients with major depressive disorder.","26342888",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26444022","Practice Effects and Stability of Neuropsychological and UHDRS Tests Over Short Retest Intervals in Huntington Disease.","26444022",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26553313","Multicenter, randomized, placebo-controlled, double-blind clinical trial of escitalopram on the progression-delaying effects in Alzheimer's disease.","26553313",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"26899575","Citalopram Ameliorates Synaptic Plasticity Deficits in Different Cognition-Associated Brain Regions Induced by Social Isolation in Middle-Aged Rats.","26899575",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27716660","The Effect of Escitalopram on Mood and Cognition in Depressive Alzheimer's Disease Subjects.","27716660",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28212943","Effects of acute dopaminergic and serotonergic manipulations in the ACI paradigm depend on the basal valence of cognitive judgement bias in rats.","28212943",42]
["Citric Acid","Citric Acid","D019343","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18292441","Dehydration induced by bowel preparation in older adults does not result in cognitive dysfunction.","18292441",42]
["CL 275838","CL 275838","C074871","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7929869","Multiple-dose pharmacokinetics and safety of a potential memory-enhancing compound, CL 275,838, in healthy male volunteers.","7929869",42]
["Clemastine","Clemastine","D002974","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1347267","Placebo controlled comparison of acute effects of ebastine and clemastine on performance and EEG.","1347267",42]
["Clemastine","Clemastine","D002974","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"449773","The interaction between ethanol and antihistamines: 2. Clemastine.","449773",42]
["Clioquinol","Clioquinol","D007464","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16025421","Clioquinol treatment in familiar early onset of Alzheimer's disease: a case report.","16025421",42]
["Clioquinol","Clioquinol","D007464","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20849933","Impairment of recognition memory and hippocampal long-term potentiation after acute exposure to clioquinol.","20849933",42]
["Clioquinol","Clioquinol","D007464","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23556155","Can we reverse Alzheimer's?  New approaches from Harvard offer hope.","23556155",42]
["Clioquinol","Clioquinol","D007464","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26473791","Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer's Disease.","26473791",42]
["clobazam","clobazam","C012255","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10094425","The cognitive and behavioural effects of clobazam and standard monotherapy are comparable. Canadian Study Group for Childhood Epilepsy.","10094425",42]
["clobazam","clobazam","C012255","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"29168169","Response to clobazam in continuous spike-wave during sleep.","29168169",42]
["clobazam","clobazam","C012255","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"6129143","Nomifensine, clobazam and HOE 8476: effects on aspects of psychomotor performance and cognitive ability.","6129143",42]
["clobazam","clobazam","C012255","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6535067","Information processing and benzodiazepines.","6535067",42]
["clobenpropit","clobenpropit","C086108","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"11125734","Effects of histamine H3 receptor agonists and antagonists on cognitive performance and scopolamine-induced amnesia.","11125734",42]
["Clomipramine","Clomipramine","D002997","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"2050170","The effects of repeated doses of clomipramine and alprazolam on physiological, psychomotor and cognitive functions in normal subjects.","2050170",42]
["Clonazepam","Clonazepam","D002998","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19730280","Pharmacokinetic/pharmacodynamic modeling of psychomotor impairment induced by oral clonazepam in healthy volunteers.","19730280",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10460317","Idazoxan potentiates rather than antagonizes some of the cognitive effects of clonidine.","10460317",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10516957","Treatment with the noradrenergic alpha-2 agonist clonidine, but not diazepam, improves spatial working memory in normal young rhesus monkeys.","10516957",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1411,B1411)","v":"Clonidine"},"Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1411,K1411)","v":"Cognition"},"D003071","Cognition",0,1,1994,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1411,Q1411)","v":"10690913"},"The effect of D-amphetamine, clonidine, and yohimbine on human information processing.","10690913",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11575409","Sedative, analgesic and cognitive effects of clonidine infusions in humans.","11575409",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12685512","Effects of nicardipine and clonidine on cognitive functions and electroencephalography in hypertensive patients.","12685512",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15888511","Selective effects of clonidine and temazepam on attention and memory.","15888511",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17062304","Effects of food on the single-dose pharmacokinetics/pharmacodynamics of tizanidine capsules and tablets in healthy volunteers.","17062304",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17159617","The effect of alpha-2 adrenergic agonists on memory and cognitive flexibility.","17159617",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1749827","Clonidine and scopolamine: differences and similarities in how they change human information processing.","1749827",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17655511","Hemodynamic and cognitive effects of lofexidine and methadone coadministration: a pilot study.","17655511",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18292438","The effect of clonidine infusion on distribution of regional cerebral blood flow in volunteers.","18292438",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18784917","Protracted cognitive effects produced by clonidine in Macaca nemestrina performing a delayed matching task.","18784917",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1924516","Clonidine enhances delayed matching-to-sample performance by young and aged monkeys.","1924516",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23013802","Decreasing adrenergic or sympathetic hyperactivity after severe traumatic brain injury using propranolol and clonidine (DASH After TBI Study): study protocol for a randomized controlled trial.","23013802",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2725871","Manic-like state after bilateral orbitofrontal and right temporoparietal injury: efficacy of clonidine.","2725871",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"2824692","Noradrenergic mechanisms in age-related cognitive decline.","2824692",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28319126","Effects of sevoflurane and clonidine on acid base status and long-term emotional and cognitive outcomes in spontaneously breathing rat pups.","28319126",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"2999977","Alpha 2-adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates.","2999977",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"7905189","Postsynaptic alpha-2 receptor stimulation improves memory in aged monkeys: indirect effects of yohimbine versus direct effects of clonidine.","7905189",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7951680","A pilot study of clonidine plus physostigmine in Alzheimer's disease.","7951680",42]
["Clonidine","Clonidine","D003000","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8102313","Reserpine impairs spatial working memory performance in monkeys: reversal by the alpha 2-adrenergic agonist clonidine.","8102313",42]
["Clopenthixol","Clopenthixol","D003006","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15115949","Effects of low-dose risperidone and low-dose zuclopenthixol on cognitive functions in first-episode drug-naive schizophrenic patients.","15115949",42]
["Clopenthixol","Clopenthixol","D003006","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26819282","Frontal D2/3 Receptor Availability in Schizophrenia Patients Before and After Their First Antipsychotic Treatment: Relation to Cognitive Functions and Psychopathology.","26819282",42]
["clophen A30","clophen A30","C042165","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"9086484","Clinical data on three cases of occupationally induced PCB-intoxication.","9086484",42]
["clopidogrel","clopidogrel","C055162","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"23364229","Cerebroprotective effect of preoperative dual antiplatelet therapy in patients undergoing coronary bypass surgery.","23364229",42]
["clopidogrel","clopidogrel","C055162","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25453448","Blood pressure control after stroke: too little, too late, or too soon to tell?","25453448",42]
["clopidogrel","clopidogrel","C055162","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25453457","Effects of long-term blood pressure lowering and dual antiplatelet treatment on cognitive function in patients with recent lacunar stroke: a secondary analysis from the SPS3 randomised trial.","25453457",42]
["Clorazepate Dipotassium","Clorazepate Dipotassium","D003009","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"2869470","Effects of clorazepate dipotassium and placebo on psychomotor skills.","2869470",42]
["Clorazepate Dipotassium","Clorazepate Dipotassium","D003009","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"2896666","Depressive symptoms and intellectual functioning in anxiety patients treated with clorazepate.","2896666",42]
["clovoxamine","clovoxamine","C020724","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1523282","Amitriptyline, clovoxamine and cognitive function: a placebo-controlled comparison in depressed outpatients.","1523282",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11278154","Neuropsychological change in schizophrenia after 6 weeks of clozapine.","11278154",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10227103","A comparison of the effect of clozapine with typical neuroleptics on cognitive function in neuroleptic-responsive schizophrenia.","10227103",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10372607","The effects of clozapine on cognitive functioning in schizophrenia.","10372607",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10482343","Effects of clozapine on awareness of illness and cognition in schizophrenia.","10482343",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10545667","[Clozapine: neuropsychological and neuroimaging studies].","10545667",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10570762","Effects of clozapine on psychiatric symptoms, cognition, and functional outcome in schizophrenia.","10570762",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11186599","Haloperidol disrupts, clozapine reinstates the circadian rest-activity cycle in a patient with early-onset Alzheimer disease.","11186599",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11593072","Clozapine enhances neurocognition and clinical symptomatology more than standard neuroleptics.","11593072",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11593073","A placebo-controlled pilot study of the ampakine CX516 added to clozapine in schizophrenia.","11593073",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12502008","Insight in persons with schizophrenia: effects of switching from conventional neuroleptics to atypical antipsychotics.","12502008",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12634513","Do atypical antipsychotics fail to exert cognitive sparing effects?","12634513",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12845415","Cognitive effects of olanzapine and clozapine treatment in chronic schizophrenia.","12845415",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14763687","Gains in speeded information processing following clozapine treatment of schizophrenia.","14763687",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15965314","The effect of galantamine added to clozapine on cognition of five patients with schizophrenia.","15965314",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16171653","Patient outcomes in schizophrenia I: correlates with sociodemographic variables, psychopathology, and side effects.","16171653",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16452559","Clozapine alone versus clozapine and risperidone with refractory schizophrenia.","16452559",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17194269","A double-blind study of combination of clozapine with risperidone in patients with schizophrenia: effects on cognition.","17194269",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17237918","Clozapine, SCH 23390 and alpha-flupenthixol but not haloperidol attenuate acute phencyclidine-induced disruption of conditional discrimination performance.","17237918",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17560766","Schizophrenic patients treated with clozapine or olanzapine perform better on theory of mind tasks than those treated with risperidone or typical antipsychotic medications.","17560766",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17854919","D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats.","17854919",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18094665","Detection of the moderately beneficial cognitive effects of low-dose treatment with haloperidol or clozapine in an animal model of the attentional impairments of schizophrenia.","18094665",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"18179309","Add-on mirtazapine enhances effects on cognition in schizophrenic patients under stabilized treatment with clozapine.","18179309",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18232726","A randomized, double-blind comparison of clozapine and high-dose olanzapine in treatment-resistant patients with schizophrenia.","18232726",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18262704","Clozapine may partially compensate for task-related brain perfusion abnormalities in risperidone-resistant schizophrenia patients.","18262704",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20299191","Comparison of the efficacy and impact on cognition of glycopyrrolate and biperiden for clozapine-induced sialorrhea in schizophrenic patients: a randomized, double-blind, crossover study.","20299191",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20615930","Topiramate augmentation of clozapine in schizophrenia: a double-blind, placebo-controlled study.","20615930",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21134422","The influence of N-desmethylclozapine and clozapine on recognition memory and BDNF expression in hippocampus.","21134422",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21855612","Ameliorative effect of N-desmethylclozapine in animal models of social deficits and cognitive functions.","21855612",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22727707","Rosiglitazone and cognitive function in clozapine-treated patients with schizophrenia: a pilot study.","22727707",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23343453","Clozapine and visuospatial processing in treatment-resistant schizophrenia.","23343453",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24145221","Augmentation of clozapine with ziprasidone in refractory schizophrenia: a double-blind, placebo-controlled study.","24145221",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24715364","Neuropsychological effects of maintenance treatment with Clozapine in Treatment-Resistant Psychotic Disorder.","24715364",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26514554","Examination of clozapine and haloperidol in improving ketamine-induced deficits in an incremental repeated acquisition procedure in BALB/c mice.","26514554",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27085900","Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol.","27085900",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28405711","Effect of clozapine on ketamine-induced deficits in attentional set shift task in mice.","28405711",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"29024893","Plasma ratio of clozapine to N-desmethylclozapine can predict cognitive performance in treatment-resistant psychotic patients.","29024893",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1475,B1475)","v":"Clozapine"},"Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1475,K1475)","v":"Cognition"},"D003071","Cognition",0,1,1994,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1475,Q1475)","v":"7525543"},"The effects of clozapine on neurocognition: an overview.","7525543",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8048341","The tolerability and efficacy of the atypical neuroleptic remoxipride compared with clozapine and haloperidol in acute schizophrenia.","8048341",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8242526","Cognitive and behavioural efficacy of clozapine in clinical trials.","8242526",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8887990","The effects of clozapine on symptom reduction, neurocognitive function, and clinical management in treatment-refractory state hospital schizophrenic inpatients.","8887990",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9131723","Improvement of cognitive function in schizophrenic patients receiving clozapine or zotepine: results from a double-blind study.","9131723",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9144103","The effects of clozapine on cognitive functioning in treatment-resistant schizophrenic patients.","9144103",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9494753","Selective serotonin reuptake inhibitor modulation of clozapine effects on cognition in schizophrenia.","9494753",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9524789","Treatment-resistant schizophrenia--the role of clozapine.","9524789",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9732399","S 16924 ((R)-2-[1-[2-(2,3-dihydro-benzo[1,4] dioxin-5-yloxy)-ethyl]-pyrrolidin-3yl]-1-(4-fluoro-phenyl)-ethanone), a novel, potential antipsychotic with marked serotonin (5-HT)1A agonist properties: II. Functional profile in comparison to clozapine and haloperidol.","9732399",42]
["CNB 001","CNB 001","C529348","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22194796","A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease.","22194796",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10415669","Functional magnetic resonance imaging of brain reward circuitry in the human.","10415669",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10881254","Differential effects of cocaine and cocaine alcohol on neurocognitive performance.","10881254",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11434821","Prenatal cocaine exposure as a risk factor for later developmental outcomes.","11434821",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12711927","Executive functioning in preschool-age children prenatally exposed to alcohol, cocaine, and marijuana.","12711927",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1454043","Prenatal exposure to cocaine. II: Effects on open-field activity and cognitive behavior in Sprague-Dawley rats.","1454043",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15019425","Cocaine effects on the developing brain: current status.","15019425",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15177825","Impaired performance of children exposed in utero to cocaine on a novel test of visuospatial working memory.","15177825",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15916717","Effects of isradipine on cocaine-induced changes in cognitive performance in recently abstinent cocaine-dependent individuals.","15916717",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17683902","A meta-analysis of animal studies on disruption of spatial navigation by prenatal cocaine exposure.","17683902",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18455307","Cocaine exposure during the early postnatal period diminishes medial frontal cortex Gs coupling to dopamine D1-like receptors in adult rat.","18455307",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18539927","Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex.","18539927",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18640911","Acute effects of cocaine on the neurobiology of cognitive control.","18640911",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18640916","Review. Parallel studies of cocaine-related neural and cognitive impairment in humans and monkeys.","18640916",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19146950","Intrauterine cocaine exposure and executive functioning in middle childhood.","19146950",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19372696","Functional MRI and response inhibition in children exposed to cocaine in utero. Preliminary findings.","19372696",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19513699","Effects of self-administered cocaine in adolescent and adult male rats on orbitofrontal cortex-related neurocognitive functioning.","19513699",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19686843","Children with and without gestational cocaine exposure: a neurocognitive systems analysis.","19686843",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19695324","Continued effects of prenatal cocaine use: preschool development.","19695324",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19727676","Recreational cocaine polydrug use impairs cognitive flexibility but not working memory.","19727676",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19901826","Prior chronic cocaine exposure in mice induces persistent alterations in cognitive function.","19901826",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"21176703","[Outlines of interdisciplinary addiction research given by the example of medical imaging with PET, SPECT and fMRI regarding effects of psychotropic substances].","21176703",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21451031","Chronic cocaine self-administration in rhesus monkeys: impact on associative learning, cognitive control, and working memory.","21451031",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"21790908","Improved cognitive flexibility in serotonin transporter knockout rats is unchanged following chronic cocaine self-administration.","21790908",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22672928","Effects of chronic cocaine self-administration on cognition and cerebral glucose utilization in Rhesus monkeys.","22672928",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22836369","Acute cocaine induced deficits in cognitive performance in rhesus macaque monkeys treated with baclofen.","22836369",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22987022","Safety of atomoxetine in combination with intravenous cocaine in cocaine-experienced participants.","22987022",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23083947","Cognitive consequences of alterations in functional circuitry induced by chronic cocaine use and the potential impact for treatment.","23083947",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23108938","Latent vulnerability in cognitive performance following chronic cocaine self-administration in rhesus monkeys.","23108938",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23796972","The context dependency of extinction negates the effectiveness of cognitive enhancement to reduce cocaine-primed reinstatement.","23796972",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2387150","Freebase cocaine and memory.","2387150",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23876288","Characterizing the cognitive effects of cocaine: a comprehensive review.","23876288",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24106872","Single doses of THC and cocaine decrease proficiency of impulse control in heavy cannabis users.","24106872",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"2431864","Cocaine effects on electroencephalographic cognitive event-related potentials and performance.","2431864",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24859175","The effects of cocaine and mazindol on the cognitive judgement bias of rats in the ambiguous-cue interpretation paradigm.","24859175",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25187977","Cocaine and cognition: a systematic quantitative review.","25187977",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25222545","A critical review of the literature on attentional bias in cocaine use disorder and suggestions for future research.","25222545",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25633093","Effects of prior cocaine self-administration on cognitive performance in female cynomolgus monkeys.","25633093",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25778776","Effects of prenatal cocaine exposure on adolescent development.","25778776",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26054440","Prenatal cocaine exposure impairs cognitive function of progeny via insulin growth factor II epigenetic regulation.","26054440",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26171607","Altered CSMD1 Expression Alters Cocaine-Conditioned Place Preference: Mutual Support for a Complex Locus from Human and Mouse Models.","26171607",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26512421","Effect of cocaine dependence on brain connections: clinical implications.","26512421",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26667034","Cannabis and cocaine decrease cognitive impulse control and functional corticostriatal connectivity in drug users with low activity DBH genotypes.","26667034",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26953708","Prenatal cocaine exposure and its impact on cognitive functions of offspring: a pathophysiological insight.","26953708",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27114202","Altered activity-based sleep measures in rhesus monkeys following cocaine self-administration and abstinence.","27114202",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27114203","The effects of oral d-amphetamine on impulsivity in smoked and intranasal cocaine users.","27114203",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28220045","Paternal cocaine taking elicits epigenetic remodeling and memory deficits in male progeny.","28220045",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"3931143","Information processing components of the auditory event related potential are reduced by cocaine.","3931143",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1978,"666941","Awareness during endotracheal intubation.","666941",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6724760","Drug-induced ego states. I. Cocaine: phenomenology and implications.","6724760",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7954158","Neurodevelopment of adopted children exposed in utero to cocaine.","7954158",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8809854","Psychomotor and electroencephalographic sequelae of cocaine dependence.","8809854",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8809859","Neuropsychological abnormalities in cocaine abusers: possible correlates in SPECT neuroimaging.","8809859",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8926291","Cognitive effects of cocaine and polydrug abuse.","8926291",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8947940","Prenatal cocaine and/or nicotine exposure in rats: preliminary findings on long-term cognitive outcome and genital development at birth.","8947940",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1539,B1539)","v":"Cocaine"},"Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1539,K1539)","v":"Cognition"},"D003071","Cognition",0,1,1997,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1539,Q1539)","v":"9211446"},"Event-related potential changes in cocaine withdrawal: evidence for long-term cognitive effects.","9211446",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9467799","Cognitive-neuromotor assessment of substance abuse: focus on issues related to cocaine abuse treatment.","9467799",42]
["Coconut Oil","Coconut Oil","D000074263","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26667739","[COCONUT OIL: NON-ALTERNATIVE DRUG TREATMENT AGAINST ALZHEIMER´S DISEASE].","26667739",42]
["Coconut Oil","Coconut Oil","D000074263","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28118770","Enhanced memory in Wistar rats by virgin coconut oil is associated with increased antioxidative, cholinergic activities and reduced oxidative stress.","28118770",42]
["Coconut Oil","Coconut Oil","D000074263","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28421789","How does coconut oil affect cognitive performance in alzheimer patients?","28421789",42]
["Codeine","Codeine","D003061","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"19919582","Patients with problematic opioid use can be weaned from codeine without pain escalation.","19919582",42]
["Codeine","Codeine","D003061","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9860110","Subjective, psychomotor, and analgesic effects of oral codeine and morphine in healthy volunteers.","9860110",42]
["coenzyme Q10","coenzyme Q10","C024989","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11916321","Therapeutic trial in the first three Asian cases of ethylmalonic encephalopathy: response to riboflavin.","11916321",42]
["coenzyme Q10","coenzyme Q10","C024989","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15246848","Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease.","15246848",42]
["coenzyme Q10","coenzyme Q10","C024989","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19710165","Prolonged intake of coenzyme Q10 impairs cognitive functions in mice.","19710165",42]
["coenzyme Q10","coenzyme Q10","C024989","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25149567","Coenzyme Q10 and α-tocopherol reversed age-associated functional impairments in mice.","25149567",42]
["coenzyme Q10","coenzyme Q10","C024989","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25792086","The effect of creatine and coenzyme q10 combination therapy on mild cognitive impairment in Parkinson's disease.","25792086",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10823400","A naturalistic investigation of the effects of day-long consumption of tea, coffee and water on alertness, sleep onset and sleep quality.","10823400",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12397002","Coffee consumption and cognitive function among older adults.","12397002",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16170233","Caffeine deprivation state modulates coffee consumption but not attentional bias for caffeine-related stimuli.","16170233",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17679672","The neuroprotective effects of caffeine: a prospective population study (the Three City Study).","17679672",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17766225","[From coffee to today's drugs: review of an uncommon book].","17766225",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17987647","Combined effects of smoking, coffee, and NSAIDs on Parkinson's disease risk.","17987647",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21693129","Chronic coffee and caffeine ingestion effects on the cognitive function and antioxidant system of rat brains.","21693129",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19587088","Coffee drinking in middle age is not associated with cognitive performance in old age.","19587088",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"20306773","Assessing the association between pesticide exposure and cognitive development in rural Costa Rican children living in organic and conventional coffee farms.","20306773",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"21773723","Does coffee enriched with chlorogenic acids improve mood and cognition after acute administration in healthy elderly? A pilot study.","21773723",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22140584","Smart drugs \"as common as coffee\": media hype about neuroenhancement.","22140584",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23006223","[Coffee can protect against disease].","23006223",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23319129","Epidemiologic evidence of a relationship between tea, coffee, or caffeine consumption and cognitive decline.","23319129",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23344884","Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging.","23344884",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24349389","A randomised placebo-controlled trial to differentiate the acute cognitive and mood effects of chlorogenic acid from decaffeinated coffee.","24349389",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24676319","Current evidence for the use of coffee and caffeine to prevent age-related cognitive decline and Alzheimer's disease.","24676319",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24895603","Habitual coffee consumption enhances attention and vigilance in hemodialysis patients.","24895603",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25072440","The Use of Caffeinated Substances by Surgeons for Cognitive Enhancement.","25072440",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25732217","Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review.","25732217",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26445565","The effect of an acute ingestion of Turkish coffee on reaction time and time trial performance.","26445565",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26932511","The influence of espresso coffee on neurocognitive function in HIV-infected patients.","26932511",42]
["Coffee","Coffee","D003069","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27163820","Association of Coffee Consumption with MRI Markers and Cognitive Function: A Population-Based Study.","27163820",42]
["Colchicine","Colchicine","D003078","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"2017442","Microtubule disruption and cognitive defects: effect of colchicine on learning behavior in rats.","2017442",42]
["Colchicine","Colchicine","D003078","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24075937","Lycopene protects against memory impairment and mito-oxidative damage induced by colchicine in rats: an evidence of nitric oxide signaling.","24075937",42]
["Colchicine","Colchicine","D003078","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8180792","Comparison of intracranial infusions of colchicine and ibotenic acid as models of neurodegeneration in the basal forebrain.","8180792",42]
["conessine","conessine","C007111","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18683917","The alkaloid conessine and analogues as potent histamine H3 receptor antagonists.","18683917",42]
["Congo Red","Congo Red","D003224","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17095235","Systemic administration of Congo red does not improve motor or cognitive function in R6/2 mice.","17095235",42]
["coomassie Brilliant Blue","coomassie Brilliant Blue","C004692","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25193238","Brilliant Blue G improves cognition in an animal model of Alzheimer's disease and inhibits amyloid-β-induced loss of filopodia and dendrite spines in hippocampal neurons.","25193238",42]
["copper (II) diacetyl-di(N(4)-methylthiosemicarbazone)","copper (II) diacetyl-di(N(4)-methylthiosemicarbazone)","C089548","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22473957","The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease.","22473957",42]
["Coptidis rhizoma extract","Coptidis rhizoma extract","C107393","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28946610","Coptidis Rhizoma Prevents Heat Stress-Induced Brain Damage and Cognitive Impairment in Mice.","28946610",42]
["coptisine","coptisine","C034384","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25079795","The IDO inhibitor coptisine ameliorates cognitive impairment in a mouse model of Alzheimer's disease.","25079795",42]
["Corn Oil","Corn Oil","D003314","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18676533","Effect of supplementing pregnant and lactating mothers with n-3 very-long-chain fatty acids on children's IQ and body mass index at 7 years of age.","18676533",42]
["Cotinine","Cotinine","D003367","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27775852","Cotinine administration improves impaired cognition in the mouse model of Fragile X syndrome.","27775852",42]
["Cotinine","Cotinine","D003367","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23199696","Association of blood cotinine level with cognitive and physical performance in non-smoking older adults.","23199696",42]
["Cotinine","Cotinine","D003367","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"24970109","New Insights into the Mechanisms of Action of Cotinine and its Distinctive Effects from Nicotine.","24970109",42]
["Cotinine","Cotinine","D003367","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25933960","Pharmacokinetics of cotinine in rats: a potential therapeutic agent for disorders of cognitive function.","25933960",42]
["Cotinine","Cotinine","D003367","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26812049","Passive Smoke Exposure and Its Effects on Cognition, Sleep, and Health Outcomes in Overweight and Obese Children.","26812049",42]
["Cotinine","Cotinine","D003367","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9258989","Safety of cotinine in humans: physiologic, subjective, and cognitive effects.","9258989",42]
["Cotinine","Cotinine","D003367","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9497017","Effects of cotinine on information processing in nonsmokers.","9497017",42]
["CP 101581","CP 101581","C106677","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9151770","Effects of the novel NMDA antagonists CP-98,113, CP-101,581 and CP-101,606 on cognitive function and regional cerebral edema following experimental brain injury in the rat.","9151770",42]
["CP 98113","CP 98113","C106676","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9151770","Effects of the novel NMDA antagonists CP-98,113, CP-101,581 and CP-101,606 on cognitive function and regional cerebral edema following experimental brain injury in the rat.","9151770",42]
["CP 98113","CP 98113","C106676","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9593949","Effects of the NMDA antagonist CP-98,113 on regional cerebral edema and cardiovascular, cognitive, and neurobehavioral function following experimental brain injury in the rat.","9593949",42]
["CP-809,101","CP-809,101","C518685","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24196946","Stimulation of 5-HT2C receptors improves cognitive deficits induced by human tryptophan hydroxylase 2 loss of function mutation.","24196946",42]
["Crack Cocaine","Crack Cocaine","D016578","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"20001290","Neuropsychological assessment of current and past crack cocaine users.","20001290",42]
["Creatinine","Creatinine","D003404","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22751104","Cyclocreatine treatment improves cognition in mice with creatine transporter deficiency.","22751104",42]
["crezacin","crezacin","C047413","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18383733","[Functional and metabolic changes of healthy volunteers after cold exposure and administration of meteoadaptogen trekrezan].","18383733",42]
["crocin","crocin","C029036","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23351962","Protective effects of oral crocin against intracerebroventricular streptozotocin-induced spatial memory deficit and oxidative stress in rats.","23351962",42]
["crocin","crocin","C029036","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28098452","A Perspective on Crocus sativus L. (Saffron) Constituent Crocin: A Potent Water-Soluble Antioxidant and Potential Therapy for Alzheimer's Disease.","28098452",42]
["Cromolyn Sodium","Cromolyn Sodium","D004205","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1976,"824535","The effect of disodium cromoglycate on human performance, alone and in combination with ethanol.","824535",42]
["cryptotanshinone","cryptotanshinone","C037886","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17714702","Tanshinone congeners improve memory impairments induced by scopolamine on passive avoidance tasks in mice.","17714702",42]
["Cuprizone","Cuprizone","D003471","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25347963","Brain metabolite changes in subcortical regions after exposure to cuprizone for 6 weeks: potential implications for schizophrenia.","25347963",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19329286","Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT).","19329286",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1603,B1603)","v":"Curcumin"},"Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1603,K1603)","v":"Cognition"},"D003071","Cognition",0,1,2009,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1603,Q1603)","v":"19765566"},"Curcumin is protective against phenytoin-induced cognitive impairment and oxidative stress in rats.","19765566",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20816821","A pyrazole curcumin derivative restores membrane homeostasis disrupted after brain trauma.","20816821",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22194796","A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease.","22194796",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22359574","Curcumin enhances neurogenesis and cognition in aged rats: implications for transcriptional interactions related to growth and synaptic plasticity.","22359574",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23609199","Curcumin improves spatial memory and decreases oxidative damage in aged female rats.","23609199",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"23911971","Dietary strategy to repair plasma membrane after brain trauma: implications for plasticity and cognition.","23911971",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23954730","Free and nanoencapsulated curcumin suppress β-amyloid-induced cognitive impairments in rats: involvement of BDNF and Akt/GSK-3β signaling pathway.","23954730",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24914461","Effects of curcumin on learning and memory deficits, BDNF, and ERK protein expression in rats exposed to chronic unpredictable stress.","24914461",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25041840","Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice.","25041840",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25217884","Curcumin and hesperidin improve cognition by suppressing mitochondrial dysfunction and apoptosis induced by D-galactose in rat brain.","25217884",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25277322","Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population.","25277322",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25330677","[Effect of curcumin on the injury in hippocampal neurons and the expression of RANTES in hippocamp during cerebral ischemia/ reperfusion in spontaneously hypertensive rats SHR].","25330677",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26114940","Curcumin Improves Amyloid β-Peptide (1-42) Induced Spatial Memory Deficits through BDNF-ERK Signaling Pathway.","26114940",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26652155","Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease.","26652155",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26702989","Autophagic activation: A key piece of the puzzle for the curcumin-associated cognitive enhancement?","26702989",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27102361","Curcumin and cognition: a randomised, placebo-controlled, double-blind study of community-dwelling older adults.","27102361",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28801114","Effects of curcumin on short-term spatial and recognition memory, adult neurogenesis and neuroinflammation in a streptozotocin-induced rat model of dementia of Alzheimer's type.","28801114",42]
["Curcumin","Curcumin","D003474","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"29287782","Naringenin-induced enhanced antioxidant defence system meliorates cholinergic neurotransmission and consolidates memory in male rats.","29287782",42]
["CX717","CX717","C542518","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"18985324","Mechanisms underlying cognitive enhancement and reversal of cognitive deficits in nonhuman primates by the ampakine CX717.","18985324",42]
["CX717","CX717","C542518","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"22171951","Effects of the putative cognitive-enhancing ampakine, CX717, on attention and object recognition memory.","22171951",42]
["cyanogen","cyanogen","C011206","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24481810","Determinants of cognitive performance in children relying on cyanogenic cassava as staple food.","24481810",42]
["Cyclazocine","Cyclazocine","D003496","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"4011631","Comparison of anorexia and motor disruption by cyclazocine and quipazine.","4011631",42]
["Cyclazocine","Cyclazocine","D003496","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1975,"765293","A controlled comparison of cyclazocine and naloxone treatment of the paroled narcotic addict.","765293",42]
["cyclobenzaprine","cyclobenzaprine","C004704","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9443520","Lack of sedative and cognitive effects of diphenhydramine and cyclobenzaprine in elderly volunteers.","9443520",42]
["cyclocreatine","cyclocreatine","C012260","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22751104","Cyclocreatine treatment improves cognition in mice with creatine transporter deficiency.","22751104",42]
["Cycloheximide","Cycloheximide","D003513","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21535411","Tacrine and bis(7)-tacrine attenuate cycloheximide-induced amnesia in mice, with attention to acute toxicity.","21535411",42]
["cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester","cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester","C500528","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26238495","Inhibition of fatty-acid amide hydrolyse (FAAH) exerts cognitive improvements in male but not female rats.","26238495",42]
["cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester","cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester","C500528","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28042028","URB597 improves cognitive impairment induced by chronic cerebral hypoperfusion by inhibiting mTOR-dependent autophagy.","28042028",42]
["cyclohexyl methylphosphonofluoridate","cyclohexyl methylphosphonofluoridate","C053914","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21741405","Effects of low-level sarin and cyclosarin exposure and Gulf War Illness on brain structure and function: a study at 4T.","21741405",42]
["Cyclophosphamide","Cyclophosphamide","D003520","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16397043","Transient improvement in cognitive function and synaptic plasticity in rats following cancer chemotherapy.","16397043",42]
["Cyclophosphamide","Cyclophosphamide","D003520","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15957521","One-year cyclophosphamide treatment combined with methylprednisolone improves cognitive dysfunction in progressive forms of multiple sclerosis.","15957521",42]
["Cyclophosphamide","Cyclophosphamide","D003520","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26057360","Doxorubicin and cyclophosphamide treatment produces anxiety-like behavior and spatial cognition impairment in rats: Possible involvement of hippocampal neurogenesis via brain-derived neurotrophic factor and cyclin D1 regulation.","26057360",42]
["cypermethrin","cypermethrin","C017160","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"29020013","In utero and lactational exposure to low-doses of the pyrethroid insecticide cypermethrin leads to neurodevelopmental defects in male mice-An ethological and transcriptomic study.","29020013",42]
["Cyproheptadine","Cyproheptadine","D003533","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27632557","Pharmacokinetics, Safety and Cognitive Function Profile of Rupatadine 10, 20 and 40 mg in Healthy Japanese Subjects: A Randomised Placebo-Controlled Trial.","27632557",42]
["Cyproterone Acetate","Cyproterone Acetate","D017373","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11379383","The role of antiandrogens in hormone replacement therapy.","11379383",42]
["Cysteamine","Cysteamine","D003543","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"2874527","Huntington's disease: effect of cysteamine, a somatostatin-depleting agent.","2874527",42]
["Cysteamine","Cysteamine","D003543","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"2905659","Somatostatin and SMS 201-995 reverse the impairment of cognitive functions induced by cysteamine depletion of brain somatostatin.","2905659",42]
["Cysteamine","Cysteamine","D003543","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9247075","Long-term effects of cysteamine on cognitive and locomotor behavior in rats: relationship to hippocampal glial pathology and somatostatin levels.","9247075",42]
["Dabigatran","Dabigatran","D000069604","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26289705","Reversible Cognitive Impairment Associated with the Use of Dabigatran.","26289705",42]
["Dacarbazine","Dacarbazine","D003606","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22093943","Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Cancer Research (SAKK 70/03).","22093943",42]
["Dacarbazine","Dacarbazine","D003606","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23642624","Health-related quality of life in elderly patients with newly diagnosed glioblastoma treated with short-course radiation therapy plus concomitant and adjuvant temozolomide.","23642624",42]
["Dacarbazine","Dacarbazine","D003606","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23729276","Prospective evaluation of health-related quality of life in patients with glioblastoma multiforme treated on a phase II trial of hypofractionated IMRT with temozolomide.","23729276",42]
["daidzein","daidzein","C004742","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15259285","The effects of dietary supplementation with isoflavones from red clover on cognitive function in postmenopausal women.","15259285",42]
["daidzein","daidzein","C004742","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"16137014","[Effect of soybean isoflavone on the cognitive function in ovariectomized mice].","16137014",42]
["daidzein","daidzein","C004742","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27804870","Daidzein and its Effects on Brain.","27804870",42]
["daidzein","daidzein","C004742","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19054783","A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and women.","19054783",42]
["dammarane","dammarane","C102963","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25965066","In Silico and In Vitro Analysis of Bacoside A Aglycones and Its Derivatives as the Constituents Responsible for the Cognitive Effects of Bacopa monnieri.","25965066",42]
["danggui-shaoyao-san","danggui-shaoyao-san","C531150","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20117199","Danggui-Shaoyao-San and its active fraction JD-30 improve Abeta-induced spatial recognition deficits in mice.","20117199",42]
["danggui-shaoyao-san","danggui-shaoyao-san","C531150","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22414474","Danggui-Shaoyao-San ameliorates cognition deficits and attenuates oxidative stress-related neuronal apoptosis in d-galactose-induced senescent mice.","22414474",42]
["danggui-shaoyao-san","danggui-shaoyao-san","C531150","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27163672","Neuroprotective effects of Danggui-Jakyak-San on rat stroke model through antioxidant/antiapoptotic pathway.","27163672",42]
["dan-shen root extract","dan-shen root extract","C028972","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9503422","[Ameliorating effects of dan-shen and its major ingredient calcium/magnesium lithospermate B on cognitive deficiencies in senescence-accelerated mouse].","9503422",42]
["dapoxetine","dapoxetine","C080598","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17322143","Dapoxetine has no pharmacokinetic or cognitive interactions with ethanol in healthy male volunteers.","17322143",42]
["dapoxetine-N-oxide","dapoxetine-N-oxide","C522496","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17322143","Dapoxetine has no pharmacokinetic or cognitive interactions with ethanol in healthy male volunteers.","17322143",42]
["darifenacin","darifenacin","C101207","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15643227","Assessment of cognitive function of the elderly population: effects of darifenacin.","15643227",42]
["darifenacin","darifenacin","C101207","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16225528","Pharmacodynamic effects of darifenacin, a muscarinic M selective receptor antagonist for the treatment of overactive bladder, in healthy volunteers.","16225528",42]
["darifenacin","darifenacin","C101207","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16767455","[Anticholinergics for overactive bladder: does subtype selectivity play a role?].","16767455",42]
["darifenacin","darifenacin","C101207","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26391900","Treatment of Overactive Bladder in the Elderly Female: The Case for Trospium, Oxybutynin, Fesoterodine and Darifenacin.","26391900",42]
["Darunavir","Darunavir","D000069454","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27216134","Short Communication: The Impact of Switching from Atripla to Darunavir/Ritonavir Monotherapy on Neurocognition, Quality of Life, and Sleep: Results from a Randomized Controlled Study.","27216134",42]
["DDT","DDT","D003634","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"19057715","Influence of glutathione S-transferase polymorphisms on cognitive functioning effects induced by p,p'-DDT among preschoolers.","19057715",42]
["DDT","DDT","D003634","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22766752","In-utero exposure to dichlorodiphenyltrichloroethane and cognitive development among infants and school-aged children.","22766752",42]
["DDT","DDT","D003634","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26414943","Prenatal DDT and DDE exposure and child IQ in the CHAMACOS cohort.","26414943",42]
["Deanol","Deanol","D003642","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"120549","The effects of deanol on cognitive performance and electrophysiology in elderly humans.","120549",42]
["Deferoxamine","Deferoxamine","D003676","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28249040","Effects of deferoxamine on blood-brain barrier disruption after subarachnoid hemorrhage.","28249040",42]
["Deferoxamine","Deferoxamine","D003676","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28963052","Deferoxamine enhances alternative activation of microglia and inhibits amyloid beta deposits in APP/PS1 mice.","28963052",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1667,B1667)","v":"delta(9-11)-tetrahydrocannabinol"},"delta(9-11)-tetrahydrocannabinol","C052413","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1667,K1667)","v":"Cognition"},"D003071","Cognition",0,1,1998,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1667,Q1667)","v":"9795096"},"Inhibition of hippocampal acetylcholine release after acute and repeated Delta9-tetrahydrocannabinol in rats.","9795096",42]
["denbufylline","denbufylline","C043898","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10559567","Denbufylline in dementia: a double-blind controlled study.","10559567",42]
["Dental Amalgam","Dental Amalgam","D003723","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17661216","Comments on the article \"the toxicology of mercury and its chemical compounds\" by Clarkson and Magos (2006).","17661216",42]
["Dental Amalgam","Dental Amalgam","D003723","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17868887","Neuropsychological function in children with blood lead levels &lt;10 microg/dL.","17868887",42]
["Dental Amalgam","Dental Amalgam","D003723","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19464677","Neuropsychological function in school-age children with low mercury exposures.","19464677",42]
["Dental Amalgam","Dental Amalgam","D003723","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22906860","Dental composite restorations and neuropsychological development in children: treatment level analysis from a randomized clinical trial.","22906860",42]
["Dental Amalgam","Dental Amalgam","D003723","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"23064204","Prenatal exposure to dental amalgam in the Seychelles Child Development Nutrition Study: associations with neurodevelopmental outcomes at 9 and 30 months.","23064204",42]
["Dental Amalgam","Dental Amalgam","D003723","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7499646","Dental amalgam and cognitive function in older women: findings from the Nun Study.","7499646",42]
["deoxyelephantopin","deoxyelephantopin","C528427","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2018,"29792878","Deoxyelephantopin ameliorates lipopolysaccharides (LPS)-induced memory impairments in rats: Evidence for its anti-neuroinflammatory properties.","29792878",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10624999","Recovery of cognitive function after remifentanil-propofol anesthesia: a comparison with desflurane and sevoflurane anesthesia.","10624999",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11575408","Recovery and neurological examination after remifentanil-desflurane or fentanyl-desflurane anaesthesia for carotid artery surgery.","11575408",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11726429","The recovery of cognitive function after general anesthesia in elderly patients: a comparison of desflurane and sevoflurane.","11726429",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1389842","Recovery of cognitive functions after anaesthesia with desflurane or isoflurane and nitrous oxide.","1389842",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16171660","Choice of volatile anesthetic for the morbidly obese patient: sevoflurane or desflurane.","16171660",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17485435","Emergence and early cognitive function in the elderly after xenon or desflurane anaesthesia: a double-blinded randomized controlled trial.","17485435",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19608833","A comparison between sevoflurane and desflurane anesthesia in patients undergoing craniotomy for supratentorial intracranial surgery.","19608833",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21501129","The influence of propofol or desflurane on postoperative cognitive dysfunction in patients undergoing coronary artery bypass surgery.","21501129",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22075020","The effects of isoflurane and desflurane on cognitive function in humans.","22075020",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25100438","Cognitive recovery after ambulatory anaesthesia based on desflurane or propofol: a prospective randomised study.","25100438",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25738734","Effect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer's disease (review).","25738734",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26232124","Comparison of early recovery and cognitive function after desflurane and sevoflurane anaesthesia in elderly patients: A meta-analysis of randomized controlled trials.","26232124",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27562558","From the Cover: Volatile Anesthetics Transiently Disrupt Neuronal Development in Neonatal Rats.","27562558",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27930598","The anhepatic phase extended by temporary portocaval shunt does not affect anesthetic sensitivity and postoperative cognitive function: A case-control study.","27930598",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7486102","Sevoflurane versus desflurane for outpatient anesthesia: a comparison of maintenance and recovery profiles.","7486102",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8720886","[Awakening from anesthesia and recovery of cognitive function after desflurane or isoflurane].","8720886",42]
["desflurane","desflurane","C053562","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9579499","Changing from isoflurane to desflurane toward the end of anesthesia does not accelerate recovery in humans.","9579499",42]
["Desipramine","Desipramine","D003891","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17077810","Chronic treatment with desipramine improves cognitive performance of rats in an attentional set-shifting test.","17077810",42]
["Desipramine","Desipramine","D003891","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20417676","Beneficial effects of desipramine on cognitive function of chronically stressed rats are mediated by alpha1-adrenergic receptors in medial prefrontal cortex.","20417676",42]
["Desipramine","Desipramine","D003891","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24503278","The effects of acute pharmacological stimulation of the 5-HT, NA and DA systems on the cognitive judgement bias of rats in the ambiguous-cue interpretation paradigm.","24503278",42]
["Desipramine","Desipramine","D003891","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24955552","Comparison of sertraline, venlafaxine and desipramine effects on depression, cognition and the daily living activities in Alzheimer patients.","24955552",42]
["Desipramine","Desipramine","D003891","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3510796","Treatment of childhood hyperactivity with desipramine: plasma drug concentration, cardiovascular effects, plasma and urinary catecholamine levels, and clinical response.","3510796",42]
["Desipramine","Desipramine","D003891","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1983,"6230891","Effects of amitriptyline, desipramine and zimeldine, alone and in combination with ethanol, on information processing and memory in healthy volunteers.","6230891",42]
["Desipramine","Desipramine","D003891","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6589660","The effects of desmethylimipramine on cognitive function in healthy subjects.","6589660",42]
["desloratadine","desloratadine","C121345","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14582817","A comparison of the effect of diphenhydramine and desloratadine on vigilance and cognitive function during treatment of ragweed-induced allergic rhinitis.","14582817",42]
["desoxyepothilone B","desoxyepothilone B","C114026","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20943926","Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy.","20943926",42]
["Desvenlafaxine Succinate","Desvenlafaxine Succinate","D000069468","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27009044","The effect of desvenlafaxine on cognitive functioning in employed outpatients with major depressive disorder: a substudy of a randomized, double-blind, placebo-controlled trial.","27009044",42]
["Desvenlafaxine Succinate","Desvenlafaxine Succinate","D000069468","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27280963","The effects of desvenlafaxine on neurocognitive and work functioning in employed outpatients with major depressive disorder.","27280963",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14764770","Cognitive and motor development of children with and without congenital adrenal hyperplasia after early-prenatal dexamethasone.","14764770",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15215491","Postnatal dexamethasone for lung disease of prematurity.","15215491",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15814210","Minor neurological dysfunction, cognitive development, and somatic development at the age of 3 to 7 years after dexamethasone treatment in very-low birth-weight infants.","15814210",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17148562","Cognitive functions in children at risk for congenital adrenal hyperplasia treated prenatally with dexamethasone.","17148562",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18755792","Effects of prenatal dexamethasone treatment on physical growth, pituitary-adrenal hormones, and performance of motor, motivational, and cognitive tasks in juvenile and adolescent common marmoset monkeys.","18755792",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1930053","Effects of dexamethasone and high terrestrial altitude on cognitive performance and affect.","1930053",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19616002","Direct and dam-mediated effects of prenatal dexamethasone on emotionality, cognition and HPA axis in adult Wistar rats.","19616002",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21484237","Working memory performance and cognitive flexibility after dexamethasone or hydrocortisone administration in healthy volunteers.","21484237",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22549088","Cognitive outcome of offspring from dexamethasone-treated pregnancies at risk for congenital adrenal hyperplasia due to 21-hydroxylase deficiency.","22549088",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22631044","Antenatal dexamethasone has no adverse effects on child physical and cognitive development: a long-term cohort follow-up investigation.","22631044",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"23186079","Cognitive and social function in girls with congenital adrenal hyperplasia -- influence of prenatally administered dexamethasone.","23186079",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23634895","Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice.","23634895",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23832430","Neuropsychological outcomes of a randomized trial of prednisone versus dexamethasone in acute lymphoblastic leukemia: findings from Dana-Farber Cancer Institute All Consortium Protocol 00-01.","23832430",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24532490","Does dexamethasone induce more neuropsychological side effects than prednisone in pediatric acute lymphoblastic leukemia? A systematic review.","24532490",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24602475","Functional outcome at school age of preterm-born children treated with high-dose dexamethasone.","24602475",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25012880","The quality of general movements after treatment with low-dose dexamethasone in preterm infants at risk of bronchopulmonary dysplasia.","25012880",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25665056","Dexamethasone but not the equivalent doses of hydrocortisone induces neurotoxicity in neonatal rat brain.","25665056",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26052629","Dexamethasone therapy for preventing delayed encephalopathy after carbon monoxide poisoning.","26052629",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26383033","Prenatal glucocorticoid exposure in rats: programming effects on stress reactivity and cognition in adult offspring.","26383033",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6363659","Effects of antenatal dexamethasone administration in the infant: long-term follow-up.","6363659",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8198631","Glucocorticoid-induced impairment in declarative memory performance in adult humans.","8198631",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8532827","Effects of early prenatal dexamethasone on the cognitive and behavioral development of young children: results of a pilot study.","8532827",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9125609","A placebo-controlled comparison between betamethasone and dexamethasone for fetal maturation: differences in neurobehavioral development of mice offspring.","9125609",42]
["dexefaroxan","dexefaroxan","C451723","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"11907173","Effects of acute and subchronic administration of dexefaroxan, an alpha(2)-adrenoceptor antagonist, on memory performance in young adult and aged rodents.","11907173",42]
["Dexmedetomidine","Dexmedetomidine","D020927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10702460","Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions.","10702460",42]
["Dexmedetomidine","Dexmedetomidine","D020927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12172293","Dexmedetomidine may impair cognitive testing during endovascular embolization of cerebral arteriovenous malformations: a retrospective case report series.","12172293",42]
["Dexmedetomidine","Dexmedetomidine","D020927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15021281","Dexmedetomidine for awake carotid endarterectomy: efficacy, hemodynamic profile, and side effects.","15021281",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1731,B1731)","v":"Dexmedetomidine"},"Dexmedetomidine","D020927","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1731,K1731)","v":"Cognition"},"D003071","Cognition",0,1,2010,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1731,Q1731)","v":"20376430"},"Cognitive improvement during continuous sedation in critically ill, awake and responsive patients: the Acute Neurological ICU Sedation Trial (ANIST).","20376430",42]
["Dexmedetomidine","Dexmedetomidine","D020927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24140296","Dexmedetomidine preserves attention/calculation when used for cooperative and short-term intensive care unit sedation.","24140296",42]
["Dexmedetomidine","Dexmedetomidine","D020927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24849450","[Effects of different doses of dexmedetomidine on cognitive dysfunction in elderly patients early after laparoscopic surgery for colorectal cancer].","24849450",42]
["Dexmedetomidine","Dexmedetomidine","D020927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25769330","[Effects of dexmedetomidine on recovery period of anesthesia and postoperative cognitive function after robot-assisted laparoscopicradical prostatectomy in the elderly people].","25769330",42]
["Dexmedetomidine","Dexmedetomidine","D020927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25860207","Neurocognitive dysfunction risk alleviation with the use of dexmedetomidine in perioperative conditions or as ICU sedation: a meta-analysis.","25860207",42]
["Dexmedetomidine","Dexmedetomidine","D020927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26016826","Efficacy of perioperative dexmedetomidine in postoperative neurocognitive function: a meta-analysis.","26016826",42]
["Dexmedetomidine","Dexmedetomidine","D020927","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27555140","Influence of dexmedetomidine on cognitive function in volunteers.","27555140",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"10690913","The effect of D-amphetamine, clonidine, and yohimbine on human information processing.","10690913",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10901342","Effects of dextroamphetamine on depression and fatigue in men with HIV: a double-blind, placebo-controlled trial.","10901342",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10944409","Effects of dextroamphetamine on cognitive performance and cortical activation.","10944409",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11099758","Reduction of latent inhibition by D-amphetamine in a conditioned suppression paradigm in humans.","11099758",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11277604","Effects of d-amphetamine on the performance of rats in an animal analogue of the A-X continuous performance test.","11277604",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12766934","Relationship of plasma amphetamine levels to physiological, subjective, cognitive and biochemical measures in healthy volunteers.","12766934",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12887140","Effects of tyrosine, phentermine, caffeine D-amphetamine, and placebo on cognitive and motor performance deficits during sleep deprivation.","12887140",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15378673","Development of a statistical approach to classifying treatment response in individual children with ADHD.","15378673",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16120100","Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.","16120100",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16796223","The effects of caffeine, dextroamphetamine, and modafinil on humor appreciation during sleep deprivation.","16796223",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16946193","Sex differences in amphetamine-induced displacement of [(18)F]fallypride in striatal and extrastriatal regions: a PET study.","16946193",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17469936","Behavioral and subjective effects of d-amphetamine and modafinil in healthy adults.","17469936",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17484308","Psychostimulants and military operations.","17484308",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17714844","Riluzole and D-amphetamine interactions in humans.","17714844",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18322858","The effects of modafinil, caffeine, and dextroamphetamine on judgments of simple versus complex emotional expressions following sleep deprivation.","18322858",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"18372722","Relative bioavailability of scopolamine dosage forms and interaction with dextroamphetamine.","18372722",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9377538","Self-monitoring cognitive performance during sleep deprivation: effects of modafinil, d-amphetamine and placebo.","9377538",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1976,"944861","Paradoxical response to amphetamine in developing rats treated with 6-hydroxydopamine.","944861",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18474395","Disulfiram enhances subjective effects of dextroamphetamine in humans.","18474395",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18785355","Restoration of risk-propensity during sleep deprivation: caffeine, dextroamphetamine, and modafinil.","18785355",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1984711","Cognitive and behavioral effects of the coadministration of dextroamphetamine and haloperidol in schizophrenia.","1984711",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20399212","The effects of progesterone pretreatment on the response to oral d-amphetamine in Women.","20399212",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20521327","Use of an acute challenge with d-amphetamine to model cognitive improvement in chronic schizophrenia.","20521327",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"2066768","The effect of amphetamine on regional cerebral blood flow during cognitive activation in schizophrenia.","2066768",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21408181","Performance deficits of NK1 receptor knockout mice in the 5-choice serial reaction-time task: effects of d-amphetamine, stress and time of day.","21408181",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2180255","Beyond drug effects and dependent variables: the use of the Poisson-Erlang model to assess the effects of D-amphetamine on information processing.","2180255",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"21894485","Effect of d-amphetamine on post-error slowing in healthy volunteers.","21894485",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22453140","Sensitivity to cognitive effort mediates psychostimulant effects on a novel rodent cost/benefit decision-making task.","22453140",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23273721","A thalamocorticostriatal dopamine network for psychostimulant-enhanced human cognitive flexibility.","23273721",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24297663","Randomized, double-blind, placebo-controlled, crossover study of the effects of lisdexamfetamine dimesylate and mixed amphetamine salts on cognition throughout the day in adults with attention-deficit/hyperactivity disorder.","24297663",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24503278","The effects of acute pharmacological stimulation of the 5-HT, NA and DA systems on the cognitive judgement bias of rats in the ambiguous-cue interpretation paradigm.","24503278",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26177580","Cross-site strain comparison of pharmacological deficits in the touchscreen visual discrimination test.","26177580",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27114203","The effects of oral d-amphetamine on impulsivity in smoked and intranasal cocaine users.","27114203",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2742729","The effects of d-amphetamine on arousal, cognition, and mood after prolonged total sleep deprivation.","2742729",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3390096","Effects of scopolamine and dextroamphetamine on human performance.","3390096",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1978,"341313","Dextroamphetamine: cognitive and behavioral effects in normal prepubertal boys.","341313",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3772051","The effects of stimulant drugs on information processing in elderly adults.","3772051",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1972,"4402496","Symposium: behavior modification by drugs. II. Psychological effects of stimulant drugs in children with minimal brain dysfunction.","4402496",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1970,"4942686","Objective effects of dexamphetamine and amobarbital and their relations to psychasthenic personality traits.","4942686",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1968,"5661749","The effects of psilocybin, dextro-amphetamine and placebo on performance of the trail making test.","5661749",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"6798619","Perseverative behaviour after amphetamine; dissociation of response tendency from reward association.","6798619",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1980,"7360831","Dextroamphetamine: cognitive and behavioral effects in normal and hyperactive boys and normal adult males.","7360831",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1980,"7365116","Cognitive processes in normal and hyperactive children and their response to amphetamine treatment.","7365116",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8764668","Dextroamphetamine enhances \"neural network-specific\" physiological signals: a positron-emission tomography rCBF study.","8764668",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"8988795","Minimal effects of dextroamphetamine on scopolamine-induced cognitive impairments in humans.","8988795",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9234049","Effects of d-amphetamine on task performance and social behavior of humans in a residential laboratory.","9234049",42]
["Dextroamphetamine","Dextroamphetamine","D003913","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9704869","Lithium does not attenuate the effects of D-amphetamine in healthy volunteers.","9704869",42]
["Dextromethorphan","Dextromethorphan","D003915","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19619574","Neuroprotective profile of dextromethorphan in an experimental model of penetrating ballistic-like brain injury.","19619574",42]
["Dextromethorphan","Dextromethorphan","D003915","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22989498","Acute cognitive effects of high doses of dextromethorphan relative to triazolam in humans.","22989498",42]
["Dextromethorphan","Dextromethorphan","D003915","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24702319","Low doses of dextromethorphan have a beneficial effect in the treatment of neuropathic pain.","24702319",42]
["Dextromethorphan","Dextromethorphan","D003915","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26887382","Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan.","26887382",42]
["Dextromethorphan","Dextromethorphan","D003915","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27905499","The correlation between plasma brain-derived neurotrophic factor and cognitive function in bipolar disorder is modulated by the BDNF Val66Met polymorphism.","27905499",42]
["Dextropropoxyphene","Dextropropoxyphene","D011431","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10692620","The cognitive and psychomotor effects of morphine in healthy subjects: a randomized controlled trial of repeated (four) oral doses of dextropropoxyphene, morphine, lorazepam and placebo.","10692620",42]
["Dextropropoxyphene","Dextropropoxyphene","D011431","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14725952","Characterizing the subjective, psychomotor, and physiological effects of oral propoxyphene in non-drug-abusing volunteers.","14725952",42]
["Dextropropoxyphene","Dextropropoxyphene","D011431","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1743247","Enhancement of propoxyphene bioavailability by ethanol. Relation to psychomotor and cognitive function in healthy volunteers.","1743247",42]
["Dextropropoxyphene","Dextropropoxyphene","D011431","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8582462","The cognitive and psychomotor effects of opioid analgesics. I. A randomized controlled trial of single doses of dextropropoxyphene, lorazepam and placebo in healthy subjects.","8582462",42]
["dezocine","dezocine","C010827","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1348168","Subjective, behavioral, and physiologic responses to intravenous dezocine in healthy volunteers.","1348168",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1795,B1795)","v":"dezocine"},"dezocine","C010827","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1795,K1795)","v":"Cognition"},"D003071","Cognition",0,1,2015,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1795,Q1795)","v":"26125754"},"Effects of intravenous analgesia with combined dezocine and butorphanol on postoperative cognitive function in elderly patients.","26125754",42]
["dezocine","dezocine","C010827","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8823239","Opioid antagonist effects of dezocine in opioid-dependent humans.","8823239",42]
["diallyl disulfide","diallyl disulfide","C028009","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23732363","Diallyl disulfide impairs hippocampal neurogenesis in the young adult brain.","23732363",42]
["diaminobutanoyl(7)-leiurotoxin I","diaminobutanoyl(7)-leiurotoxin I","C442227","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18561910","Small-conductance Ca(2+)-activated K(+) channels: Heterogeneous affinity in rat brain structures and cognitive modulation by specific blockers.","18561910",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10463323","Dissociating neuromodulatory effects of diazepam on episodic memory encoding and executive function.","10463323",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10516957","Treatment with the noradrenergic alpha-2 agonist clonidine, but not diazepam, improves spatial working memory in normal young rhesus monkeys.","10516957",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10760494","Positive and negative modulation of the GABA(A) receptor and outcome after traumatic brain injury in rats.","10760494",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1975,"1104773","A review of the effects of diazepam on cognitive and psychomotor performance.","1104773",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11401011","Lorazepam and diazepam impair true, but not false, recognition in healthy volunteers.","11401011",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1294894","Cognition and vigilance: differential effects of diazepam and buspirone on memory and psychomotor performance.","1294894",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14689162","Diazepam produces disinhibitory cognitive effects in male volunteers.","14689162",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1523286","Differential effects of diazepam and lorazepam on repetition priming in healthy volunteers.","1523286",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1539066","Behavioral efficacy of diazepam against nerve agent exposure in rhesus monkeys.","1539066",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17020910","Diazepam dose-dependently increases or decreases implicit priming of alcohol associations in problem drinkers.","17020910",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17676319","Voriconazole and fluconazole increase the exposure to oral diazepam.","17676319",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"7871037","Subjective and behavioral effects of diazepam depend on its rate of onset.","7871037",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7871082","Lorazepam and diazepam effects on memory acquisition in priming tasks.","7871082",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19265570","The differential role of alpha1- and alpha5-containing GABA(A) receptors in mediating diazepam effects on spontaneous locomotor activity and water-maze learning and memory in rats.","19265570",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"20110024","Effects of treatment with etizolam 0.5 mg BID on cognitive performance: a 3-week, multicenter, randomized, double-blind, placebo-controlled, two-treatment, three-period, noninferiority crossover study in patients with anxiety disorder.","20110024",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"2025471","Reversal of benzodiazepine sedation with the antagonist flumazenil.","2025471",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20373478","The effects of acute treatment with tandospirone, diazepam, and placebo on driving performance and cognitive function in healthy volunteers.","20373478",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20540443","Extending submarine crew survival by reducing CO2 production with quickly reversible sedation.","20540443",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"2062989","Comparison of the amnesic effects of midazolam and diazepam.","2062989",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20863004","Effects of multiple-dose esomeprazole and pantoprazole on diazepam pharmacokinetic profile and pharmacodynamic effects on cognitive and psychomotor function in healthy volunteers.","20863004",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21458503","Behavioural and neural effects of diazepam on a rule-guided response selection task.","21458503",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1990,"2276384","Effects of single doses of alprazolam and diazepam, alone and in combination with ethanol, on psychomotor and cognitive performance and on autonomic nervous system reactivity in healthy volunteers.","2276384",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1977,"23704","The effect of diazepam and lorazepam on awareness during anaesthesia for Caesarian section.","23704",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2611075","Comparison of diazepam with midazolam as i.v. sedation for outpatient gastroscopy.","2611075",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2682593","Actions and interactions of psychotropic drugs on human performance and mood: single doses of ORG 3770, amitriptyline, and diazepam.","2682593",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26828763","Beneficial effects of ellagic acid against animal models of scopolamine- and diazepam-induced cognitive impairments.","26828763",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27150079","Cognitive mechanisms of diazepam administration: a healthy volunteer model of emotional processing.","27150079",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"286027","Comparison of recovery tests after intravenous sedation with diazepam-methohexital and diazepam-methohexital and fentanyl.","286027",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1989,"2928433","Effects of diazepam on a belief-updating task.","2928433",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3094049","Performance effects of diazepam during and after prolonged administration.","3094049",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3103156","Effects of diazepam on cognitive processes in normal subjects.","3103156",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3137626","The effects on memory of pipequaline, alone or in combination with diazepam.","3137626",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1988,"3268886","[Effect of diazepam on cognitive and psychomotor functions in patients with neuroses in relation to various anxiety levels].","3268886",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3517081","Pharmacokinetic and pharmacodynamic interactions between caffeine and diazepam.","3517081",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3602037","Interactions of diazepam and caffeine: behavioral and subjective dose effects in humans.","3602037",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3628442","Differential CNS effects of diazepam in elderly adults.","3628442",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3816528","Comparison of two benzodiazepines in the treatment of alcohol withdrawal: effects on symptoms and cognitive recovery.","3816528",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"3925486","Naloxone's effect on cognitive functioning in drug-free and diazepam-treated normal humans.","3925486",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"4068771","Gender-related differences in diazepam effects on performance.","4068771",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1973,"4198305","Preanesthetic medication in elective surgery: comparison of intravenous diazepam with meperidine.","4198305",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1973,"4589809","Antianxiety drugs and human performance.","4589809",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1974,"4597697","Combined effects of diazepam and ethanol on mental and psychomotor functions.","4597697",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1973,"4801720","Mental and psychomotor effects of diazepam and ethanol.","4801720",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1969,"5347462","Diazepam and awareness.","5347462",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"552582","Studies of cognitive function as influenced by administration of haloperidol or diazepam in detoxification of acute alcoholics.","552582",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"6121766","Comparative effects of diazepam and buspirone on subjective feelings, psychological tests and the EEG.","6121766",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6329901","Effects of valium and librium on human psychomotor and cognitive functions.","6329901",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1983,"6374311","Caffeine and theophylline counteract diazepam effects in man.","6374311",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6387529","Behavioral effects of diazepam and propranolol in patients with panic disorder and agoraphobia.","6387529",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6427816","Dose-response analysis of the behavioral effects of diazepam: I. Learning and memory.","6427816",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6427817","Dose-response analysis of the behavioral effects of diazepam: II. Psychomotor performance, cognition and mood.","6427817",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6438672","Relative abuse liability of diazepam and oxazepam: behavioral and subjective dose effects.","6438672",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6438674","Diazepam and memory: retrograde facilitation produced by interference reduction.","6438674",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6483935","Behavioral effects of oral versus intravenous administration of diazepam.","6483935",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1978,"660514","Effect of diazepam on cognition via pupillometry.","660514",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6697644","Effects of oral contraceptives on diazepam-induced psychomotor impairment.","6697644",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"7122662","Diazepam and learning: assessment of acquisition deficits.","7122662",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"7138754","Influence of cimetidine on oral diazepam elimination with measurement of subsequent cognitive change.","7138754",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"7202239","Diazepam and self or externally paced letter matching tasks.","7202239",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"7285487","Onset of peak impairment after diazepam and after alcohol.","7285487",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1859,B1859)","v":"Diazepam"},"Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1859,K1859)","v":"Cognition"},"D003071","Cognition",0,1,1995,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1859,Q1859)","v":"7480522"},"Primacy and recency effects in rhesus monkeys (Macaca mulatta) using a serial probe recognition task. I. Effects of diazepam.","7480522",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7814823","Differential acute psychomotor and cognitive effects of diazepam on long-term benzodiazepine users.","7814823",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7988580","Metabolic and subjective responses to oral diazepam and midazolam.","7988580",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1976,"824215","Clinical and psychological effects of intravenous diazepam related to plasma levels. A controlled, double-blind, cross-over study in oral surgery involving local analgesia.","824215",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8426714","Comparison of oral triazolam and nitrous oxide with placebo and intravenous diazepam for outpatient premedication.","8426714",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8550117","Studies on psychomotor performance in healthy volunteers after diazepam, propranolol and alcohol given alone or in combination.","8550117",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8880945","Effects of lorazepam and diazepam on conscious and automatic memory processes.","8880945",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9100711","Effect of a single dose of diazepam on balance measures in older people.","9100711",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9101342","Influence of diazepam and buspirone on human heart rate and the evoked cardiac response under varying cognitive load.","9101342",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9288408","Event-related potentials in a passive and active auditory condition: effects of diazepam and buspirone on slow wave positivity.","9288408",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9596205","A single-blind, crossover comparison of the pharmacokinetics and cognitive effects of a new diazepam rectal gel with intravenous diazepam.","9596205",42]
["Diazepam","Diazepam","D003975","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1976,"987727","Effect of morphine-diazepam on signs of anesthesia, awareness, and dreams of patients under N2O for cesarean section.","987727",42]
["Diazinon","Diazinon","D003976","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16166182","A long-term study of the effects of diazinon on sleep, the electrocorticogram and cognitive behaviour in common marmosets.","16166182",42]
["Diazoxide","Diazoxide","D003981","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23327786","Cognitive and developmental outcome of conservatively treated children with congenital hyperinsulinism.","23327786",42]
["Diazoxide","Diazoxide","D003981","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24090223","Development of thiophenic analogues of benzothiadiazine dioxides as new powerful potentiators of 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA) receptors.","24090223",42]
["dibenzo(1,4)dioxin","dibenzo(1,4)dioxin","C020887","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26824471","Impacts of Perinatal Dioxin Exposure on Motor Coordination and Higher Cognitive Development in Vietnamese Preschool Children: A Five-Year Follow-Up.","26824471",42]
["Dichlorodiphenyl Dichloroethylene","Dichlorodiphenyl Dichloroethylene","D003633","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22766752","In-utero exposure to dichlorodiphenyltrichloroethane and cognitive development among infants and school-aged children.","22766752",42]
["Dichlorodiphenyl Dichloroethylene","Dichlorodiphenyl Dichloroethylene","D003633","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23085522","Evaluating the neurotoxic effects of lactational exposure to persistent organic pollutants (POPs) in Spanish children.","23085522",42]
["Dichlorodiphenyl Dichloroethylene","Dichlorodiphenyl Dichloroethylene","D003633","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26414943","Prenatal DDT and DDE exposure and child IQ in the CHAMACOS cohort.","26414943",42]
["didesethylflurazepam","didesethylflurazepam","C033473","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"6761826","A clinical study of flurazepam.","6761826",42]
["Diethylhexyl Phthalate","Diethylhexyl Phthalate","D004051","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"22610992","Perinatal exposure to Di-(2-ethylhexyl)-Phthalate leads to cognitive dysfunction and phospho-tau level increase in aged rats.","22610992",42]
["Diethylhexyl Phthalate","Diethylhexyl Phthalate","D004051","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26516888","In Utero Exposure to Diethylhexyl Phthalate Affects Rat Brain Development: A Behavioral and Genomic Approach.","26516888",42]
["Diethylnitrosamine","Diethylnitrosamine","D004052","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"20387270","Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's disease.","20387270",42]
["Diethylstilbestrol","Diethylstilbestrol","D004054","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12737934","Perinatal exposure to diethylstilbestrol improves olfactory discrimination learning in male and female Swiss-Webster mice.","12737934",42]
["Diethylstilbestrol","Diethylstilbestrol","D004054","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1398561","Prenatal diethylstilbestrol exposure and performance on college entrance examinations.","1398561",42]
["Diethylstilbestrol","Diethylstilbestrol","D004054","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15451043","Endocrine disruption and cognitive function in adolescent female rhesus monkeys.","15451043",42]
["Diethylstilbestrol","Diethylstilbestrol","D004054","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"9047262","Sexual differentiation of cognitive abilities in women exposed to diethylstilbestrol (DES) prenatally.","9047262",42]
["Digoxin","Digoxin","D004077","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19220067","Digoxin and cognitive performance in patients with heart failure: a cohort, pharmacoepidemiological survey.","19220067",42]
["dihydrexidine","dihydrexidine","C061532","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8624125","The D1 agonist dihydrexidine releases acetylcholine and improves cognition in rats.","8624125",42]
["dihydrexidine","dihydrexidine","C061532","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26966119","A proof-of-concept, randomized controlled trial of DAR-0100A, a dopamine-1 receptor agonist, for cognitive enhancement in schizophrenia.","26966119",42]
["dihydrexidine","dihydrexidine","C061532","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27440209","Highlights from the 2016 Schizophrenia International Research Society Conference, April 2-6, 2016.","27440209",42]
["dihydrexidine","dihydrexidine","C061532","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9300608","D1 agonist dihydrexidine releases acetylcholine and improves cognitive performance in rats.","9300608",42]
["dihydroagarofuran","dihydroagarofuran","C079978","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26295746","Natural β-Dihydroagarofuran-Type Sesquiterpenoids as Cognition-Enhancing and Neuroprotective Agents from Medicinal Plants of the Genus Celastrus.","26295746",42]
["Dihydroergotoxine","Dihydroergotoxine","D004088","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1492862","[The effect of dihydroergocristine on cognitive functions and sleep in elderly subjects].","1492862",42]
["Dihydroergotoxine","Dihydroergotoxine","D004088","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23528488","[Vasobral in the treatment of brain lesions: views of physicians and patients].","23528488",42]
["Dihydroergotoxine","Dihydroergotoxine","D004088","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1987,"3819261","A controlled double-blind study of high-dose dihydroergotoxine mesylate (Hydergine) in mild dementia.","3819261",42]
["Dihydroergotoxine","Dihydroergotoxine","D004088","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1977,"406875","Pharmacotherapy for organic brain syndrome in late life. Evaluation of an ergot derivative vs placebo.","406875",42]
["Dihydroergotoxine","Dihydroergotoxine","D004088","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1985,"4094447","Effects of Hydergine and its components on Lashley maze acquisition in rats.","4094447",42]
["Dihydroergotoxine","Dihydroergotoxine","D004088","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"536469","The effects of an ergot alkaloid derivative (Hydergine) on aspects of psychomotor performance, arousal, and cognitive processing ability.","536469",42]
["Dihydroergotoxine","Dihydroergotoxine","D004088","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1982,"7201839","[On the meaning of psychometrically operationalized therapeutic effects in the treatment of brain insufficiency phenomena caused by old age demonstrated by the \"Nürnberger-Alters-Inventar\" (author's transl)].","7201839",42]
["Dihydroergotoxine","Dihydroergotoxine","D004088","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"7204812","Senile dementia: combined pharmacologic and psychologic treatment.","7204812",42]
["Dihydroergotoxine","Dihydroergotoxine","D004088","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1976,"823192","An ergot alkaloid preparation (Hydergine) in the treatment of dementia: critical review of the clinical literature.","823192",42]
["Dilazep","Dilazep","D004109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12627880","Effects of the anti-platelet aggregation drug dilazep on cognitive function in Dahl salt-sensitive rats.","12627880",42]
["Dimenhydrinate","Dimenhydrinate","D004111","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"17765381","Dimenhydrinate effect on cerebral oxygen status and salivary chromogranin-A during cognitive tasks.","17765381",42]
["Dimethyl Sulfoxide","Dimethyl Sulfoxide","D004121","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1975,"1055559","Oral dimethyl sulfoxide in mental retardation. Part 1. Preliminary behavioral and psychometric data. Part 2: Preliminary medical data.","1055559",42]
["dimiracetam","dimiracetam","C085079","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8277504","Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones, a novel class of potent cognition enhancers.","8277504",42]
["Dinoprost","Dinoprost","D015237","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11768373","Dietary antioxidants and dementia.","11768373",42]
["Diosgenin","Diosgenin","D004144","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24292207","Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D₃-MARRS.","24292207",42]
["Diosmin","Diosmin","D004145","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28738538","Diosmin improved cognitive deficit and amplified brain electrical activity in the rat model of traumatic brain injury.","28738538",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1978,"100808","Methamphetamine and diphenhydramine effects on the rate of cognitive processing.","100808",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11749824","Effect of H1-antagonists on spatial memory deficit evaluated by 8-arm radial maze in rats.","11749824",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12602446","The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel.","12602446",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12775138","Effects of fexofenadine, diphenhydramine, and placebo on performance of the test of variables of attention (TOVA).","12775138",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14582817","A comparison of the effect of diphenhydramine and desloratadine on vigilance and cognitive function during treatment of ragweed-induced allergic rhinitis.","14582817",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1501118","Subjective and behavioral effects of diphenhydramine, lorazepam and methocarbamol: evaluation of abuse liability.","1501118",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9361576","Initial and steady-state effects of diphenhydramine and loratadine on sedation, cognition, mood, and psychomotor performance.","9361576",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9443520","Lack of sedative and cognitive effects of diphenhydramine and cyclobenzaprine in elderly volunteers.","9443520",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27018419","Next-day residual effects of gabapentin, diphenhydramine, and triazolam on simulated driving performance in healthy volunteers: a phase 3, randomized, double-blind, placebo-controlled, crossover trial.","27018419",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28251653","Successful intervention to mitigate an acetylcholinesterase inhibitor-induced rhinorrhea prescribing cascade: a case report.","28251653",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7489665","Pharmacologically induced changes in arousal: effects on behavioral and electrophysiologic measures of alertness and attention.","7489665",42]
["Diphenhydramine","Diphenhydramine","D004155","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8368986","The effects of Benadryl and Hismanal on psychomotor performance and perceived performance.","8368986",42]
["diphenyldiselenide","diphenyldiselenide","C061132","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23085182","Cognitive effects of diphenyl diselenide and estradiol treatments in ovariectomized mice.","23085182",42]
["Diphtheria-Tetanus-Pertussis Vaccine","Diphtheria-Tetanus-Pertussis Vaccine","D015721","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25185528","Early exposure to thimerosal-containing vaccines and children's cognitive development. A 9-year prospective birth cohort study in Poland.","25185528",42]
["dipropizine","dipropizine","C035916","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8223138","Enantioselective effects of levodropropizine and dropropizine on psychomotor functions in normal volunteers: a placebo-controlled, double-blind comparative study.","8223138",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1923,B1923)","v":"Disulfiram"},"Disulfiram","D004221","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1923,K1923)","v":"Cognition"},"D003071","Cognition",0,1,2008,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1923,Q1923)","v":"18474395"},"Disulfiram enhances subjective effects of dextroamphetamine in humans.","18474395",42]
["Disulfiram","Disulfiram","D004221","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"384831","Effect of disulfiram on cognition, subjective response, and cortical-event-related potentials in nonalcoholic subjects.","384831",42]
["Disulfoton","Disulfoton","D004222","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1993,"8449387","Characterization of disulfoton-induced behavioral and neurochemical effects following repeated exposure.","8449387",42]
["di-tan decoction","di-tan decoction","C000604598","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25925312","The efficacy and safety of the Chinese herbal medicine Di-Tan decoction for treating Alzheimer's disease: protocol for a randomized controlled trial.","25925312",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11485835","Differential effects of two NMDA receptor antagonists on cognitive-behavioral development in nonhuman primates I.","11485835",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11485836","Differential effects of two NMDA receptor antagonists on cognitive--behavioral performance in young nonhuman primates II.","11485836",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12589526","Chronic treatment with caffeine blunts the hyperlocomotor but not cognitive effects of the N-methyl-D-aspartate receptor antagonist MK-801 in mice.","12589526",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12853303","Chronic exposure to NMDA receptor and sodium channel blockers during development in monkeys and rats: long-term effects on cognitive function.","12853303",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15276693","The dopaminergic stabiliser ACR16 counteracts the behavioural primitivization induced by the NMDA receptor antagonist MK-801 in mice: implications for cognition.","15276693",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15767842","Effect of subchronic caffeine treatment on MK-801-induced changes in locomotion, cognition and ataxia in mice.","15767842",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15956997","Cholinesterase inhibitors ameliorate behavioral deficits induced by MK-801 in mice.","15956997",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9421174","Neuropeptide Y and the calcitonin gene-related peptide attenuate learning impairments induced by MK-801 via a sigma receptor-related mechanism.","9421174",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1842701","D-cycloserine, a putative cognitive enhancer, facilitates activation of the N-methyl-D-aspartate receptor-ionophore complex in Alzheimer brain.","1842701",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19428648","Contribution of K+-Cl- cotransporter 2 in MK-801-induced impairment of long term potentiation.","19428648",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20371226","The difference in effect of mGlu2/3 and mGlu5 receptor agonists on cognitive impairment induced by MK-801.","20371226",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21114996","Persisting cognitive deficits induced by low-dose, subchronic treatment with MK-801 in adolescent rats.","21114996",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21274704","Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague-Dawley rats.","21274704",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21779401","Intra-accumbens injection of a dopamine aptamer abates MK-801-induced cognitive dysfunction in a model of schizophrenia.","21779401",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22704977","The investigation of neonatal MK-801 administration and physical environmental enrichment on emotional and cognitive functions in adult Balb/c mice.","22704977",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23178182","UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: comparison with the NMDA receptor antagonist MK-801.","23178182",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24149067","Pyrroloquinoline quinone prevents MK-801-induced stereotypical behavior and cognitive deficits in mice.","24149067",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"24304584","Modulation of hippocampus-prefrontal cortex synaptic transmission and disruption of executive cognitive functions by MK-801.","24304584",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24399737","Effect of combined treatment with mirtazapine and risperidone on the MK-801-induced changes in the object recognition test in mice.","24399737",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26184010","Dissociable effects of NR2A and NR2B NMDA receptor antagonism on cognitive flexibility but not pattern separation.","26184010",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26234588","Contribution of N-methyl-D-aspartate receptors to attention and episodic spatial memory during senescence.","26234588",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27512913","Effect of antidepressants on spatial memory deficit induced by dizocilpine.","27512913",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"27806441","Acute systemic MK-801 induced functional uncoupling between hippocampal areas CA3 and CA1 with distant effect in the retrosplenial cortex.","27806441",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28390877","Effects of chronic prenatal MK-801 treatment on object recognition, cognitive flexibility, and drug-induced locomotor activity in juvenile and adult rat offspring.","28390877",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8035347","Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizocilpine amnesia: putative role for allopregnanolone.","8035347",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8521903","Effects of putative cognition enhancers on the NMDA receptor by [3H]MK801 binding.","8521903",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8527744","Pregnenolone sulfate antagonizes dizocilpine amnesia: role for allopregnanolone.","8527744",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8904075","Infusion of (+) -MK-801 and memantine -- contrasting effects on radial maze learning in rats with entorhinal cortex lesion.","8904075",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9744424","Glutamate antagonism during secondary deafferentation enhances cognition and axo-dendritic integrity after traumatic brain injury.","9744424",42]
["DM 232","DM 232","C409868","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14600801","AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).","14600801",42]
["DM 232","DM 232","C409868","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16834757","Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition enhancers.","16834757",42]
["DM 232","DM 232","C409868","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"25831025","Unifi nootropics from the lab to the web: a story of academic (and industrial) shortcomings.","25831025",42]
["DM 235","DM 235","C416655","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12070754","DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer.","12070754",42]
["DM 235","DM 235","C416655","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14600801","AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).","14600801",42]
["DM 235","DM 235","C416655","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16834757","Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition enhancers.","16834757",42]
["DM 235","DM 235","C416655","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19786353","Design, synthesis and nootropic activity of new analogues of sunifiram and sapunifiram, two potent cognition-enhancers.","19786353",42]
["DM 235","DM 235","C416655","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22325944","Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs.","22325944",42]
["DM 235","DM 235","C416655","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"25831025","Unifi nootropics from the lab to the web: a story of academic (and industrial) shortcomings.","25831025",42]
["DM 235","DM 235","C416655","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28238510","Piperazines as nootropic agents: New derivatives of the potent cognition-enhancer DM235 carrying hydrophilic substituents.","28238510",42]
["docetaxel","docetaxel","C067311","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24101158","The impact of sustained and intermittent docetaxel chemotherapy regimens on cognition and neural morphology in healthy mice.","24101158",42]
["donecopride","donecopride","C000596879","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"25157130","Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.","25157130",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10634454","Donepezil therapy in clinical practice: a randomized crossover study.","10634454",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"10637404","Sustained cognitive improvement following treatment of Alzheimer's disease with donepezil.","10637404",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11290880","Donepezil, rivastigmine, and vitamin E in Alzheimer disease: a combined P300 event-related potentials/neuropsychologic evaluation over 6 months.","11290880",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"15716515","Action of cholinesterase inhibitors in patients' brains.","15716515",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10216789","Is donepezil effective for treating Alzheimer's disease?","10216789",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10523051","Comments on donepezil open label trial.","10523051",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1999,"10622675","Therapeutic standards in Alzheimer disease.","10622675",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11044775","Clinical efficacy and safety of donepezil on cognitive and global function in patients with Alzheimer's disease. A 24-week, multicenter, double-blind, placebo-controlled study in Japan. E2020 Study Group.","11044775",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11044869","Use of donepezil for the treatment of mild-moderate Alzheimer's disease: an audit of the assessment and treatment of patients in routine clinical practice.","11044869",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11351141","Chronic donepezil treatment is associated with slowed cognitive decline in Alzheimer's disease.","11351141",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11524468","A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease.","11524468",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12169217","Donepezil for cognitive impairment in Parkinson's disease: a randomized controlled trial.","12169217",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12442882","Functional, cognitive and behavioral effects of donepezil in patients with moderate Alzheimer's disease.","12442882",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12480789","Donepezil treatment of vascular dementia.","12480789",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12480794","Donepezil-treated patients with probable vascular dementia demonstrate cognitive benefits.","12480794",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12604096","Sex dimorphisms in the cognitive-enhancing action of the Alzheimer's drug donepezil in aged Rhesus monkeys.","12604096",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12700710","Cognitive enhancing properties and tolerability of cholinergic agents in mice: a comparative study of nicotine, donepezil, and SIB-1553A, a subtype-selective ligand for nicotinic acetylcholine receptors.","12700710",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12875613","A long-term comparison of galantamine and donepezil in the treatment of Alzheimer's disease.","12875613",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12970516","Efficacy and tolerability of donepezil in vascular dementia: positive results of a 24-week, multicenter, international, randomized, placebo-controlled clinical trial.","12970516",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C1987,B1987)","v":"donepezil"},"donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J1987,K1987)","v":"Cognition"},"D003071","Cognition",0,1,2004,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q1987,Q1987)","v":"14599705"},"Plasma lipid levels in Alzheimer's disease patients treated by Donepezil hydrochloride: a cross-sectional study.","14599705",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14626696","Donepezil in the treatment of mild to moderate Alzheimer's disease: report of a Belgian multicenter study.","14626696",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"14658957","Can donepezil be considered a mild antipsychotic in dementia treatment? A report of donepezil use in 6 patients.","14658957",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14715043","Efficacy and safety of donepezil in patients with Alzheimer's disease: results of a global, multinational, clinical experience study.","14715043",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14716700","A multinational, randomised, 12-week study comparing the effects of donepezil and galantamine in patients with mild to moderate Alzheimer's disease.","14716700",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14755627","Effects of acute acetylcholinesterase inhibition on the cerebral cholinergic neuronal system and cognitive function: Functional imaging of the conscious monkey brain using animal PET in combination with microdialysis.","14755627",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15000918","Donepezil minimally effective for patients with vascular dementia.","15000918",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15107192","Neuropsychological test performance in healthy volunteers before and after donepezil administration.","15107192",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15241749","Cholinergic augmentation with donepezil enhances recovery in short-term memory and sustained attention after traumatic brain injury.","15241749",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"15311761","[Significance of treatment and adequate care in dementia--including point of medical comments in health care insurance system for elderly people by doctors].","15311761",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15314255","Donepezil-induced improvement in delayed matching accuracy by young and old rhesus monkeys.","15314255",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15333988","[Pre-clinical evaluation of effects of acetylcholinesterase inhibition on the cerebral cholinergic neuronal system and cognitive function: PET study in conscious monkeys].","15333988",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15601392","Effects of donepezil on Alzheimer's disease: the relationship between cognitive function and rapid eye movement sleep.","15601392",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15603468","Effects of cognitive-communication stimulation for Alzheimer's disease patients treated with donepezil.","15603468",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20678673","Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in moderate to severe Alzheimer's disease: A 24-week, randomized, double-blind study.","20678673",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26179411","Increased dosage of donepezil for the management of behavioural and psychological symptoms of dementia in dementia with Lewy bodies.","26179411",42]
["Dopamine","Dopamine","D004298","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1979,"112679","Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey.","112679",42]
["Dopamine","Dopamine","D004298","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19428401","Dopamine and cognitive functioning in de novo subjects with Parkinson's disease: effects of pramipexole and pergolide on working memory.","19428401",42]
["Dopamine","Dopamine","D004298","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23660437","Dissociable fronto-striatal effects of dopamine D2 receptor stimulation on cognitive versus motor flexibility.","23660437",42]
["Dopamine","Dopamine","D004298","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8681493","Incremental dosage of the new antipsychotic mazapertine induces tolerance to cardiovascular and cognitive effects in healthy men.","8681493",42]
["Dronabinol","Dronabinol","D013759","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1976,"1273591","Residual learning deficit after heavy exposure to cannabis or alcohol in rats.","1273591",42]
["Eicosapentaenoic Acid","Eicosapentaenoic Acid","D015118","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24398640","Serum docosahexaenoic and eicosapentaenoic acid and risk of cognitive decline over 10 years among elderly Japanese.","24398640",42]
["epigallocatechin gallate","epigallocatechin gallate","C045651","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16549472","Long-term administration of green tea catechins improves spatial cognition learning ability in rats.","16549472",42]
["Ethanol","Ethanol","D000431","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11686489","Effects of binge ethanol administration on the behavioral outcome of rats after lateral fluid percussion brain injury.","11686489",42]
["Ethanol","Ethanol","D000431","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14982697","Psychopharmacological interactions between nicotine and ethanol.","14982697",42]
["Ethanol","Ethanol","D000431","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22327035","Low and moderate doses of acute ethanol do not impair spatial cognition but facilitate accelerating rotarod performance in adolescent and adult rats.","22327035",42]
["Ethanol","Ethanol","D000431","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24913486","Acute effects of alcohol on inhibitory control and simulated driving in DUI offenders.","24913486",42]
["Ethanol","Ethanol","D000431","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3527183","Previous alcohol intake and residual cognitive deficits in detoxified alcoholics and animals.","3527183",42]
["Ethanol","Ethanol","D000431","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6439054","Lithium antagonizes ethanol intoxication in alcoholics.","6439054",42]
["Fentanyl","Fentanyl","D005283","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16731323","A comparison of postoperative cognitive function and pain relief with fentanyl or tramadol patient-controlled analgesia.","16731323",42]
["fexofenadine","fexofenadine","C093230","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12602446","The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel.","12602446",42]
["Flumazenil","Flumazenil","D005442","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"7921859","Effectiveness of flumazenil on return of cognitive functions after a general anesthetic.","7921859",42]
["Fluoxetine","Fluoxetine","D005473","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28430602","Fluoxetine attenuates the impairment of spatial learning ability and prevents neuron loss in middle-aged APPswe/PSEN1dE9 double transgenic Alzheimer's disease mice.","28430602",42]
["Folic Acid","Folic Acid","D005492","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22566307","[Effect of folate and related nutrients on cognitive function in older people; systematic review].","22566307",42]
["Fructose","Fructose","D005632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24666585","Fructose in obesity and cognitive decline: is it the fructose or the excess energy?","24666585",42]
["Galantamine","Galantamine","D005702","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12875613","A long-term comparison of galantamine and donepezil in the treatment of Alzheimer's disease.","12875613",42]
["ginsenoside Rb1","ginsenoside Rb1","C442759","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21276426","Ginsenoside Rb1 improves spatial learning and memory by regulation of cell genesis in the hippocampal subregions of rats.","21276426",42]
["Glucose","Glucose","D005947","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"21186930","Acute effects of a glucose energy drink on behavioral control.","21186930",42]
["Glycerylphosphorylcholine","Glycerylphosphorylcholine","D005997","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1992,"1409797","Molecular mechanisms mediating the effects of L-alpha-glycerylphosphorylcholine, a new cognition-enhancing drug, on behavioral and biochemical parameters in young and aged rats.","1409797",42]
["Haloperidol","Haloperidol","D006220","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1975,"1093506","Methylphenidate and haloperidol in children. Effects on attention, memory, and activity.","1093506",42]
["Histamine","Histamine","D006632","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20685608","Cognitive domains affected by histamine H(1)-antagonism in humans: a literature review.","20685608",42]
["Hyaluronic Acid","Hyaluronic Acid","D006820","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27562609","Functional hyaluronate collagen scaffolds induce NSCs differentiation into functional neurons in repairing the traumatic brain injury.","27562609",42]
["Ibuprofen","Ibuprofen","D007052","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28254590","Subacute ibuprofen treatment rescues the synaptic and cognitive deficits in advanced-aged mice.","28254590",42]
["Isoflurane","Isoflurane","D007530","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2005,"16171660","Choice of volatile anesthetic for the morbidly obese patient: sevoflurane or desflurane.","16171660",42]
["ispronicline","ispronicline","C490152","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17225162","Effects of TC-1734 (AZD3480), a selective neuronal nicotinic receptor agonist, on cognitive performance and the EEG of young healthy male volunteers.","17225162",42]
["Ketamine","Ketamine","D007649","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21712993","Gene expression changes in GABA(A) receptors and cognition following chronic ketamine administration in mice.","21712993",42]
["Ketamine","Ketamine","D007649","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28285123","Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects.","28285123",42]
["Lactulose","Lactulose","D007792","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"29171503","[Prevention and treatment of hepatic encephalopathy].","29171503",42]
["lipoxin A4","lipoxin A4","C040527","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"25125468","Restoration of lipoxin A4 signaling reduces Alzheimer's disease-like pathology in the 3xTg-AD mouse model.","25125468",42]
["Lopinavir","Lopinavir","D061466","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20970459","Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice.","20970459",42]
["Lorazepam","Lorazepam","D008140","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7756096","Lack of interaction between a new antihistamine, mizolastine, and lorazepam on psychomotor performance and memory in healthy volunteers.","7756096",42]
["Mecamylamine","Mecamylamine","D008464","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9050073","Effects of mecamylamine on spontaneous EEG and performance in smokers and non-smokers.","9050073",42]
["Memantine","Memantine","D008559","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16861375","Memantine treatment in mild to moderate Alzheimer disease: a 24-week randomized, controlled trial.","16861375",42]
["Memantine","Memantine","D008559","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8904075","Infusion of (+) -MK-801 and memantine -- contrasting effects on radial maze learning in rats with entorhinal cortex lesion.","8904075",42]
["mephedrone","mephedrone","C548233","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28073060","Acute behavioral effects of co-administration of mephedrone and MDMA in mice.","28073060",42]
["Methamphetamine","Methamphetamine","D008694","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"25724762","The neuroprotective potential of low-dose methamphetamine in preclinical models of stroke and traumatic brain injury.","25724762",42]
["Methotrexate","Methotrexate","D008727","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17308283","Comparison of long-term neurocognitive outcomes in young children with acute lymphatic leukemia treated with cranial radiation or high-dose or very high-dose intravenous methotrexate.","17308283",42]
["Methylphenidate","Methylphenidate","D008774","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12734634","Relative lack of cognitive effects of methylphenidate in elderly male volunteers.","12734634",42]
["Methylphenidate","Methylphenidate","D008774","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19492313","Behavioral response to methylphenidate challenge: influence of early life parental care.","19492313",42]
["Methylphenidate","Methylphenidate","D008774","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1981,"6785807","Effects of lithium carbonate on methylphenidate-induced mood, behavior, and cognitive processes.","6785807",42]
["Mianserin","Mianserin","D008803","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"22750079","Predictors and mediators of add-on mirtazapine-induced cognitive enhancement in schizophrenia--a path model investigation.","22750079",42]
["Mifepristone","Mifepristone","D015735","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17464718","Changes in brain-derived neurotrophic factor following treatment with mifepristone in bipolar disorder and schizophrenia.","17464718",42]
["modafinil","modafinil","C048833","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"9377538","Self-monitoring cognitive performance during sleep deprivation: effects of modafinil, d-amphetamine and placebo.","9377538",42]
["modafinil","modafinil","C048833","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23540352","Gin and juice: modafinil tightens up the drinker's brain at rest.","23540352",42]
["Morphine","Morphine","D009020","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8582463","The cognitive and psychomotor effects of opioid analgesics. II. A randomized controlled trial of single doses of morphine, lorazepam and placebo in healthy subjects.","8582463",42]
["N,N-Dimethyltryptamine","N,N-Dimethyltryptamine","D004130","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8297217","Dose-response study of N,N-dimethyltryptamine in humans. II. Subjective effects and preliminary results of a new rating scale.","8297217",42]
["Nicardipine","Nicardipine","D009529","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12685512","Effects of nicardipine and clonidine on cognitive functions and electroencephalography in hypertensive patients.","12685512",42]
["Nicotine","Nicotine","D009538","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12225705","Effects of cigarette smoking and nicotine nasal spray on psychiatric symptoms and cognition in schizophrenia.","12225705",42]
["Nicotine","Nicotine","D009538","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2007,"17666709","Pharmacological and chemical effects of cigarette additives.","17666709",42]
["Nicotine","Nicotine","D009538","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26436562","Nicotine intake and problem solving strategies are modified during a cognitively demanding water maze task in rats.","26436562",42]
["Nicotine","Nicotine","D009538","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1998,"9739007","Nicotine interacts with sex in affecting rat choice between \"look-out\" and \"navigational\" cognitive styles in the Morris water maze place learning task.","9739007",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C5059,B5059)","v":"Nitric Oxide"},"Nitric Oxide","D009569","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J5059,K5059)","v":"Cognition"},"D003071","Cognition",0,1,2017,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q5059,Q5059)","v":"28262854"},"Effect of Insulin on Visuo-Spatial Memory and Histology of Cerebral Cortex in the Presence or Absence of Nitric Oxide Inhibition.","28262854",42]
["Nitrous Oxide","Nitrous Oxide","D009609","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1976,"987727","Effect of morphine-diazepam on signs of anesthesia, awareness, and dreams of patients under N2O for cesarean section.","987727",42]
["N-methyltropan-3-yl 2-(phenylthio)propionate","N-methyltropan-3-yl 2-(phenylthio)propionate","C087569","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1994,"8201606","Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 2. 2-Phenoxy-, 2-(phenylthio)-, and 2-(phenylamino)alkanoic acid esters.","8201606",42]
["norpseudoephedrine","norpseudoephedrine","C005331","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26070760","\"Natural Amphetamine\" Khat: A Cultural Tradition or a Drug of Abuse?","26070760",42]
["olanzapine","olanzapine","C076029","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"14615877","Randomized, controlled, double-blind, multicenter comparison of the cognitive effects of ziprasidone versus olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder.","14615877",42]
["Ondansetron","Ondansetron","D017294","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"8539321","Ondansetron improves cognitive performance in the Morris water maze spatial navigation task.","8539321",42]
["Particulate Matter","Particulate Matter","D052638","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18006900","Association of black carbon with cognition among children in a prospective birth cohort study.","18006900",42]
["perampanel","perampanel","C551441","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27595590","Pharmacokinetics, exposure-cognition, and exposure-efficacy relationships of perampanel in adolescents with inadequately controlled partial-onset seizures.","27595590",42]
["Phencyclidine","Phencyclidine","D010622","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1997,"8981615","Intrahippocampal injections of phencyclidine but not naloxone disrupt acquisition of a spatial continuous recognition memory task.","8981615",42]
["Phenylethyl Alcohol","Phenylethyl Alcohol","D010626","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"27287957","Hydroxytyrosol mildly improve cognitive function independent of APP processing in APP/PS1 mice.","27287957",42]
["pioglitazone","pioglitazone","C060836","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24628640","Sustained 4-year cognitive and functional response in early Alzheimer's disease with pioglitazone.","24628640",42]
["Piracetam","Piracetam","D010889","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2009,"19955348","Correspondence on ''the unrecognized epilepsy spectrum: the effects of levetiracetam on neuropsychological functioning in relation to subclinical spike production''.","19955348",42]
["Pirenzepine","Pirenzepine","D010890","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2003,"12845415","Cognitive effects of olanzapine and clozapine treatment in chronic schizophrenia.","12845415",42]
["pramipexole","pramipexole","C061333","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16797593","A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease.","16797593",42]
["Propofol","Propofol","D015742","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24602447","Electroconvulsive therapy pre-treatment with low dose propofol: comparison with unmodified treatment.","24602447",42]
["Propranolol","Propranolol","D011433","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2016,"26707354","Propranolol's impact on cognitive performance in post-traumatic stress disorder.","26707354",42]
["Quercetin","Quercetin","D011794","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28458424","Evaluation of neuroprotective effect of quercetin with donepezil in scopolamine-induced amnesia in rats.","28458424",42]
["reboxetine","reboxetine","C074679","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2004,"15229059","Increased positive versus negative affective perception and memory in healthy volunteers following selective serotonin and norepinephrine reuptake inhibition.","15229059",42]
["resveratrol","resveratrol","C059514","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24142524","Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi.","24142524",42]
["Risperidone","Risperidone","D018967","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2001,"11547959","The effect of risperidone on cognitive functioning in a sample of Asian patients with schizophrenia in Singapore.","11547959",42]
["Risperidone","Risperidone","D018967","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"24399737","Effect of combined treatment with mirtazapine and risperidone on the MK-801-induced changes in the object recognition test in mice.","24399737",42]
["rosiglitazone","rosiglitazone","C089730","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"20709114","Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status.","20709114",42]
["SB 399885","SB 399885","C503990","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"17069795","SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.","17069795",42]
["Scopolamine Hydrobromide","Scopolamine Hydrobromide","D012601","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1991,"1749827","Clonidine and scopolamine: differences and similarities in how they change human information processing.","1749827",42]
["Scopolamine Hydrobromide","Scopolamine Hydrobromide","D012601","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1986,"3088662","The effects of transdermal scopolamine and four dose levels of oral scopolamine (0.15, 0.3, 0.6, and 1.2 mg) upon psychological performance.","3088662",42]
["Serotonin","Serotonin","D012701","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2002,"12622180","5-HT3 receptors in selective animal models of cognition.","12622180",42]
["Serotonin","Serotonin","D012701","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2010,"20852829","Therapeutic potential of 5-HT2C receptor ligands.","20852829",42]
["Serotonin","Serotonin","D012701","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"29253878","Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer's disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid.","29253878",42]
["Sertraline","Sertraline","D020280","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26560512","Relationship Between Cerebrovascular Risk, Cognition, and Treatment Outcome in Late-Life Psychotic Depression.","26560512",42]
["Sodium Nitrite","Sodium Nitrite","D012977","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26626856","Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: a pilot trial in middle-aged and older adults.","26626856",42]
["spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one","spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one","C511224","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16474004","Effects of a novel cognitive enhancer, spiro[imidazo-[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446), on learning impairments induced by amyloid-beta1-40 in the rat.","16474004",42]
["Sulpiride","Sulpiride","D013469","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2017,"28440817","Effects of dopamine D2/D3 receptor antagonism on human planning and spatial working memory.","28440817",42]
["Tacrine","Tacrine","D013619","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"19053746","NO-donating tacrine hybrid compounds improve scopolamine-induced cognition impairment and show less hepatotoxicity.","19053746",42]
["Tea","Tea","D013662","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2014,"24304633","L-theanine (suntheanin): effects of L-theanine, an amino acid derived from Camellia sinensis (green tea), on stress response parameters.","24304633",42]
["Terfenadine","Terfenadine","D016593","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2006,"16767419","Stimulating effects of the antihistamine fexofenadine: testing the dopamine transporter hypothesis.","16767419",42]
["Theophylline","Theophylline","D013806","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1996,"8603222","Behavioral and cognitive effects of methylxanthines. A meta-analysis of theophylline and caffeine.","8603222",42]
["Toluene","Toluene","D014050","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2008,"18456329","Toluene misuse and long-term harms: a systematic review of the neuropsychological and neuroimaging literature.","18456329",42]
["topiramate","topiramate","C052342","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2012,"22481042","Topiramate and its effect on fMRI of language in patients with right or left temporal lobe epilepsy.","22481042",42]
["Triazolam","Triazolam","D014229","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2000,"11219963","Acute effects of triazolam on false recognition.","11219963",42]
["Trichloroethylene","Trichloroethylene","D014241","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2011,"21609728","A review of potential neurotoxic mechanisms among three chlorinated organic solvents.","21609728",42]
["Valproic Acid","Valproic Acid","D014635","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1984,"6425049","Sodium valproate and cognitive function.","6425049",42]
["vildagliptin","vildagliptin","C502012","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2013,"23240760","DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption.","23240760",42]
["Vitamin B 12","Vitamin B 12","D014805","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26249019","Beneficial effects of omega-3 fatty acids and vitamin B12 supplementation on brain docosahexaenoic acid, brain derived neurotrophic factor, and cognitive performance in the second-generation Wistar rats.","26249019",42]
["Vitamin K 1","Vitamin K 1","D010837","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26274973","Dietary Vitamin K Intake Is Associated with Cognition and Behaviour among Geriatric Patients: The CLIP Study.","26274973",42]
["yuan zhi","yuan zhi","C000592340","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,2015,"26199947","The Protective Effect of Radix Polygoni Multiflori on Diabetic Encephalopathy via Regulating Myosin Light Chain Kinase Expression.","26199947",42]
["zolpidem","zolpidem","C049109","8_AO",402,8,"Cognitive Function","Decreased","Cognition","D003071","Cognition",0,1,1995,"7792497","Effects of flurazepam and zolpidem on the perception of sleep in normal volunteers.","7792497",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2002,"11790513","Effects of the prolyl endopeptidase inhibitor S 17092 on cognitive deficits in chronic low dose MPTP-treated monkeys.","11790513",42]
["2-chloroethyl ethyl sulfide","2-chloroethyl ethyl sulfide","C031278","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2017,"28743565","Cognitive and emotional impairments after cutaneous intoxication by CEES (a sulfur mustard analog) in mice.","28743565",42]
["acetovanillone","acetovanillone","C056165","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2013,"24076474","The effect of NADPH-oxidase inhibitor apocynin on cognitive impairment induced by moderate lateral fluid percussion injury: role of inflammatory and oxidative brain damage.","24076474",42]
["acteoside","acteoside","C058956","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2015,"25900014","Memory Enhancement of Acteoside (Verbascoside) in a Senescent Mice Model Induced by a Combination of D-gal and AlCl3.","25900014",42]
["Amantadine","Amantadine","D000547","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1992,"1523625","[Amantadine in cognitive failure in patients with traumatic head injuries].","1523625",42]
["arsenosugar","arsenosugar","C449161","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2013,"23184187","Arsenosugar induced blood and brain oxidative stress, DNA damage and neurobehavioral impairments.","23184187",42]
["Aspirin","Aspirin","D001241","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2012,"22840457","Effect of Western medicine therapy assisted by Ginkgo biloba tablet on vascular cognitive impairment of none dementia.","22840457",42]
["blonanserin","blonanserin","C079310","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2017,"28490709","[Research progress in mechanisms and clinical application for blonanserin and lurasidone in improving cognitive function of schizophrenia].","28490709",42]
["Bromocriptine","Bromocriptine","D001971","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1987,"3671965","[Neuropsychic side effects of bromocriptine in Parkinson's disease].","3671965",42]
["Carbamazepine","Carbamazepine","D002220","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1994,"8191881","Effects of phenytoin and carbamazepine on cognitive functions in newly diagnosed epileptic patients.","8191881",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2009,"19252780","1H MR spectroscopy of gray and white matter in carbon monoxide poisoning.","19252780",42]
["Carbon Monoxide","Carbon Monoxide","D002248","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1985,"4057317","Two cases of acute carbon monoxide poisoning with delayed neurological sequelae after a \"free\" interval.","4057317",42]
["Chlorodiphenyl (54% Chlorine)","Chlorodiphenyl (54% Chlorine)","D020111","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1999,"10566587","Reduced growth of intra- and infra-pyramidal mossy fibers is produced by continuous exposure to polychlorinated biphenyl.","10566587",42]
["Cimetidine","Cimetidine","D002927","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1980,"6965483","Dose and serum concentration relationships in cimetidine-associated mental confusion.","6965483",42]
["Citalopram","Citalopram","D015283","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2015,"26356616","[Comparison of different doses of escitalopram in the prevention of dementia in patients with depression and moderate cognitive dysfunction associated with chronic brain ischemia].","26356616",42]
["Clozapine","Clozapine","D003024","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2004,"14754789","Do clozapine and risperidone affect social competence and problem solving?","14754789",42]
["Cotinine","Cotinine","D003367","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2009,"19577545","A reversible model of the cognitive impairment associated with schizophrenia in monkeys: potential therapeutic effects of two nicotinic acetylcholine receptor agonists.","19577545",42]
["Dacarbazine","Dacarbazine","D003606","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2014,"24257502","Toxicity and outcome of radiotherapy with concomitant and adjuvant temozolomide in elderly patients with glioblastoma: a retrospective study.","24257502",42]
["Dexamethasone","Dexamethasone","D003907","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2000,"10864051","Cognitive sequelae in children treated for acute lymphoblastic leukemia with dexamethasone or prednisone.","10864051",42]
["Digoxin","Digoxin","D004077","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1987,"3565623","Toxic neuropsychiatric effects of digoxin at therapeutic serum concentrations.","3565623",42]
["donepezil","donepezil","C076946","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2011,"22030437","Improvement of cognitive impairment following delayed CO encephalopathy.","22030437",42]
["Dopamine","Dopamine","D004298","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2002,"12647443","[Factors connected with the effect of risperidone on psychopathological symptoms and working memory in schizophrenia].","12647443",42]
["Dopamine","Dopamine","D004298","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2010,"20130535","Pergolide treatment of cognitive deficits associated with schizotypal personality disorder: continued evidence of the importance of the dopamine system in the schizophrenia spectrum.","20130535",42]
["Dronabinol","Dronabinol","D013759","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2009,"19384563","The depressive phenotype induced in adult female rats by adolescent exposure to THC is associated with cognitive impairment and altered neuroplasticity in the prefrontal cortex.","19384563",42]
["emoxypine succinate","emoxypine succinate","C070020","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2015,"26978058","[The possibility of treatment of cognitive impairment in the complex therapy of patients with the consequences of cerebral infarction].","26978058",42]
["Ethanol","Ethanol","D000431","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1991,"1875711","Specifying the relationship between alcohol use and cognitive loss: the effects of frequency of consumption and psychological distress.","1875711",42]
["Ethanol","Ethanol","D000431","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2014,"25020118","Selective cognitive deficits in adult rats after prenatal exposure to inhaled ethanol.","25020118",42]
["etiracetam","etiracetam","C026098","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2011,"20890680","Levetiracetam is associated with improved cognitive outcome for patients with intracranial hemorrhage.","20890680",42]
["Flurbiprofen","Flurbiprofen","D005480","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2009,"19702655","NO-flurbiprofen reduces amyloid-beta, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade.","19702655",42]
["Folic Acid","Folic Acid","D005492","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2013,"23283502","Cobalamin and folate status predicts mental development scores in North Indian children 12-18 mo of age.","23283502",42]
["Fructose","Fructose","D005632","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2005,"15985582","Cognitive and behavioral effects of lamotrigine and topiramate in healthy volunteers.","15985582",42]
["Gasoline","Gasoline","D005742","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2005,"15714227","Neurological and cognitive recovery following abstinence from petrol sniffing.","15714227",42]
["Glucose","Glucose","D005947","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2012,"22677678","[The role of brain glucose metabolism in the development of cognitive dysfunctions in patients with remitting and secondary-progressive multiple sclerosis].","22677678",42]
["Haloperidol","Haloperidol","D006220","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2002,"11738537","Does cognitive function improve with quetiapine in comparison to haloperidol?","11738537",42]
["Harmine","Harmine","D006247","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2008,"18417221","Higher blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations correlate with lower olfactory scores in essential tremor.","18417221",42]
["Indapamide","Indapamide","D007190","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2013,"23929192","[Not Available].","23929192",42]
["Isoflurane","Isoflurane","D007530","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2012,"22119003","Involvement of neuronal nitric oxide synthase in cognitive impairment in isoflurane-treated rats.","22119003",42]
["ispronicline","ispronicline","C490152","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2014,"23856296","AZD3480, a novel nicotinic receptor agonist, for the treatment of attention-deficit/hyperactivity disorder in adults.","23856296",42]
["Ketamine","Ketamine","D007649","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2011,"22020346","Using ketamine to model semantic deficits in schizophrenia.","22020346",42]
["Liuwei Dihuang Decoction","Liuwei Dihuang Decoction","C042579","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2016,"27340848","The Effects of LW-AFC on Intestinal Microbiome in Senescence-Accelerated Mouse Prone 8 Strain, a Mouse Model of Alzheimer's Disease.","27340848",42]
["Lysergic Acid Diethylamide","Lysergic Acid Diethylamide","D008238","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1970,"5286778","The uses and abuses of L.S.D. and other hallucinogenic drugs.","5286778",42]
["Medroxyprogesterone Acetate","Medroxyprogesterone Acetate","D017258","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2003,"14529594","Estrogen plus progestin may increase incidence of dementia.","14529594",42]
["Methamphetamine","Methamphetamine","D008694","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2009,"19339145","Drug abstinence and cognitive control in methamphetamine-dependent individuals.","19339145",42]
["Methohexital","Methohexital","D008723","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1995,"7854519","Anosognosia during intracarotid barbiturate anesthesia: unawareness or amnesia for weakness.","7854519",42]
["Methylazoxymethanol Acetate","Methylazoxymethanol Acetate","D008746","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2005,"15578007","Cognitive deficits caused by late gestational disruption of neurogenesis in rats: a preclinical model of schizophrenia.","15578007",42]
["Methylphenidate","Methylphenidate","D008774","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2014,"23162047","Methylphenidate enhances executive function and optimizes prefrontal function in both health and cocaine addiction.","23162047",42]
["modafinil","modafinil","C048833","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2004,"15090936","Benefits of adjunct modafinil in an open-label, pilot study in patients with schizophrenia.","15090936",42]
["N-((3-(aminomethyl)phenyl)methyl)ethanimidamide","N-((3-(aminomethyl)phenyl)methyl)ethanimidamide","C496401","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2017,"27888018","1400W ameliorates acute hypobaric hypoxia/reoxygenation-induced cognitive deficits by suppressing the induction of inducible nitric oxide synthase in rat cerebral cortex microglia.","27888018",42]
["Niacinamide","Niacinamide","D009536","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2016,"26813743","ST09, a Novel Thioester Derivative of Tacrine, Alleviates Cognitive Deficits and Enhances Glucose Metabolism in Vascular Dementia Rats.","26813743",42]
["Nicotine","Nicotine","D009538","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2012,"22717030","Nicotine fails to attenuate ketamine-induced cognitive deficits and negative and positive symptoms in humans: implications for schizophrenia.","22717030",42]
["N-Methyl-3,4-methylenedioxyamphetamine","N-Methyl-3,4-methylenedioxyamphetamine","D018817","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2005,"16128720","Mental disorders in current and former heavy ecstasy (MDMA) users.","16128720",42]
["N-Methyl-3,4-methylenedioxyamphetamine","N-Methyl-3,4-methylenedioxyamphetamine","D018817","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2014,"24830185","MDMA and the \"ecstasy paradigm\".","24830185",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C10243,B10243)","v":"olanzapine"},"olanzapine","C076029","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J10243,K10243)","v":"Cognition Disorders"},"D003072","Cognition Disorders",0,2,2002,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q10243,Q10243)","v":"12426415"},"Differential effects of olanzapine and risperidone on cognition in schizophrenia? A saccadic eye movement study.","12426415",42]
["oxcarbazepine","oxcarbazepine","C036006","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2014,"24992084","Cognitive and psychosocial effects of oxcarbazepine monotherapy in newly diagnosed partial epilepsy.","24992084",42]
["Phencyclidine","Phencyclidine","D010622","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2008,"18208936","Oestradiol attenuates the cognitive deficit induced by acute phencyclidine treatment in mature female hooded-Lister rats.","18208936",42]
["Phenobarbital","Phenobarbital","D010634","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1991,"1810228","Cognitive functions of epileptic patients on monotherapy with phenobarbitone and healthy controls.","1810228",42]
["Phosphamidon","Phosphamidon","D010707","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2011,"21257640","Effect of progesterone on phosphamidon-induced impairment of memory and oxidative stress in rats.","21257640",42]
["Pirenzepine","Pirenzepine","D010890","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2002,"12502008","Insight in persons with schizophrenia: effects of switching from conventional neuroleptics to atypical antipsychotics.","12502008",42]
["propionic acid","propionic acid","C029658","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2009,"19733590","Neurobehavioral effects during exposures to propionic acid--an indicator of chemosensory distraction?","19733590",42]
["Pyrithioxin","Pyrithioxin","D011746","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2011,"23120794","[Encephabol in the treatment of cognitive disorders in epilepsy].","23120794",42]
["Quetiapine Fumarate","Quetiapine Fumarate","D000069348","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2011,"21572163","Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD.","21572163",42]
["Risperidone","Risperidone","D018967","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2007,"17106843","[Neurotoxicity related to lithium-risperidon combination treatment in a patient with schizoaffective disorder].","17106843",42]
["Rivastigmine","Rivastigmine","D000068836","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1999,"10066203","Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomised controlled trial.","10066203",42]
["ropivacaine","ropivacaine","C037663","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2011,"22111354","[Effect of different perioperative analgesic methods on postoperative cognitive dysfunction in elderly patients undergoing upper abdominal surgery].","22111354",42]
["Scopolamine Hydrobromide","Scopolamine Hydrobromide","D012601","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2005,"15820423","Rats with scopolamine- or MK-801-induced spatial discrimination deficits in the cone field task: animal models for impaired spatial orientation performance.","15820423",42]
["Serotonin","Serotonin","D012701","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2010,"20569520","Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.","20569520",42]
["sevoflurane","sevoflurane","C009250","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2016,"27111854","Autophagy Is Involved in the Sevoflurane Anesthesia-Induced Cognitive Dysfunction of Aged Rats.","27111854",42]
["Sirolimus","Sirolimus","D020123","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2014,"24152334","The Akt-mTOR pathway in Down's syndrome: the potential use of rapamycin/rapalogs for treating cognitive deficits.","24152334",42]
["Sumatriptan","Sumatriptan","D018170","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2001,"11318884","Sumatriptan nasal spray and cognitive function during migraine: results of an open-label study.","11318884",42]
["Taurine","Taurine","D013654","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2016,"27768969","Taurine promotes cognitive function in prenatally stressed juvenile rats via activating the Akt-CREB-PGC1α pathway.","27768969",42]
["Tetrabenazine","Tetrabenazine","D013747","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2016,"26321315","Rapid Recovery of Vesicular Dopamine Levels in Methamphetamine Users in Early Abstinence.","26321315",42]
["Tobacco Smoke Pollution","Tobacco Smoke Pollution","D014028","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2005,"15866750","Exposure to environmental tobacco smoke and cognitive abilities among U.S. children and adolescents.","15866750",42]
["topiramate","topiramate","C052342","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2004,"15323603","Psychotic symptoms associated with topiramate: cognitive side effects or worsening of psychosis?","15323603",42]
["Urea","Urea","D014508","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,1988,"3150233","Cognitive development in children with inborn errors of urea synthesis.","3150233",42]
["Valproic Acid","Valproic Acid","D014635","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2008,"18695274","Outcome in West syndrome.","18695274",42]
["Vasobral","Vasobral","C055581","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2013,"23528488","[Vasobral in the treatment of brain lesions: views of physicians and patients].","23528488",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C11523,B11523)","v":"Vitamin B 12"},"Vitamin B 12","D014805","8_AO",402,8,"Cognitive Function","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J11523,K11523)","v":"Cognition Disorders"},"D003072","Cognition Disorders",0,2,1997,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q11523,Q11523)","v":"9008550"},"Cobalamine deficiency.","9008550",42]
["zolpidem","zolpidem","C049109","8_AO",402,8,"Cognitive Function","Decreased","Cognition Disorders","D003072","Cognition Disorders",0,2,2007,"17225476","Cognitive performance following premature awakening from zolpidem or melatonin induced daytime sleep.","17225476",42]
["Antipyrine","Antipyrine","D000983","8_AO",402,8,"Cognitive Function","Decreased","Cognitive Dysfunction","D060825","Cognitive Dysfunction",0,2,2016,"27116382","Protective Effects of Edaravone in Adult Rats with Surgery and Lipopolysaccharide Administration-Induced Cognitive Function Impairment.","27116382",42]
["coenzyme Q10","coenzyme Q10","C024989","8_AO",402,8,"Cognitive Function","Decreased","Cognitive Dysfunction","D060825","Cognitive Dysfunction",0,2,2016,"27693857","Neuroprotective mechanism of Coenzyme Q10 (CoQ10) against PTZ induced kindling and associated cognitive dysfunction: Possible role of microglia inhibition.","27693857",42]
["Isoflurane","Isoflurane","D007530","8_AO",402,8,"Cognitive Function","Decreased","Cognitive Dysfunction","D060825","Cognitive Dysfunction",0,2,2017,"28403230","Isoflurane anesthesia promotes cognitive impairment by inducing expression of β-amyloid protein-related factors in the hippocampus of aged rats.","28403230",42]
["Minocycline","Minocycline","D008911","8_AO",402,8,"Cognitive Function","Decreased","Cognitive Dysfunction","D060825","Cognitive Dysfunction",0,2,2016,"27061744","Minocycline attenuates post-operative cognitive impairment in aged mice by inhibiting microglia activation.","27061744",42]
["pimagedine","pimagedine","C004479","8_AO",402,8,"Cognitive Function","Decreased","Cognitive Dysfunction","D060825","Cognitive Dysfunction",0,2,2017,"28223158","Aminoguanidine alleviated MMA-induced impairment of cognitive ability in rats by downregulating oxidative stress and inflammatory reaction.","28223158",42]
["Vitamin B 12","Vitamin B 12","D014805","8_AO",402,8,"Cognitive Function","Decreased","Cognitive Dysfunction","D060825","Cognitive Dysfunction",0,2,2017,"28330909","Vitamin B-12 status in infancy is positively associated with development and cognitive functioning 5 y later in Nepalese children.","28330909",42]
["(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine","C516138","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24280125","Dorsomorphin reverses the mesenchymal phenotype of breast cancer initiating cells by inhibition of bone morphogenetic protein signaling.","24280125",42]
["1-(3-chlorophenyl)piperazine","1-(3-chlorophenyl)piperazine","C015068","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2000,"10864974","Nigrostriatal lesions alter oral dyskinesia and c-Fos expression induced by the serotonin agonist 1-(m-chlorophenyl)piperazine in adult rats.","10864974",42]
["1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","1,1-dimethylbutyl-1-deoxy-Delta(9)-THC","C432747","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"21671903","Cannabinoid CB₂ receptor-mediated regulation of impulsive-like behaviour in DBA/2 mice.","21671903",42]
["1,25-dihydroxyvitamin D","1,25-dihydroxyvitamin D","C097949","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28089917","microRNAs and DICER1 are regulated by 1,25-dihydroxyvitamin D in prostate stroma.","28089917",42]
["1,2-dithiol-3-thione","1,2-dithiol-3-thione","C049325","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2008,"18656455","Renal protection by 3H-1,2-dithiole-3-thione against cisplatin through the Nrf2-antioxidant pathway.","18656455",42]
["1,4-bis(2-(3,5-dichloropyridyloxy))benzene","1,4-bis(2-(3,5-dichloropyridyloxy))benzene","C028474","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"27113289","RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.","27113289",42]
["1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine","1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine","C026613","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18550892","Heterogeneity in the sn-1 carbon chain of platelet-activating factor glycerophospholipids determines pro- or anti-apoptotic signaling in primary neurons.","18550892",42]
["15-deoxy-delta(12,14)-prostaglandin J2","15-deoxy-delta(12,14)-prostaglandin J2","C097240","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18161004","PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo.","18161004",42]
["15-hydroxy-5,8,11,13-eicosatetraenoic acid","15-hydroxy-5,8,11,13-eicosatetraenoic acid","C025984","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22982617","Reciprocal regulation of HIF-1α and 15-LO/15-HETE promotes anti-apoptosis process in pulmonary artery smooth muscle cells during hypoxia.","22982617",42]
["1-feruloylglycerol","1-feruloylglycerol","C000611058","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28608752","Ferulic acid and its water-soluble derivatives inhibit nitric oxide production and inducible nitric oxide synthase expression in rat primary astrocytes.","28608752",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21782904","Heat shock protein 70 kDa over-expression and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigrostriatal degeneration in mice.","21782904",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28006954","The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson's Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-κB/Nuclear Transcription Factor Related to NF-E2.","28006954",42]
["1-Methyl-4-phenylpyridinium","1-Methyl-4-phenylpyridinium","D015655","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26056851","Effects of methylmercury on dopamine release in MN9D neuronal cells.","26056851",42]
["1-stearoyl-2-arachidonoyl phosphatidylinositol","1-stearoyl-2-arachidonoyl phosphatidylinositol","C070521","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20817957","Muscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis.","20817957",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C12675,B12675)","v":"2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate"},"2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate","C071738","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J12675,K12675)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,2,2013,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q12675,Q12675)","v":"23703391"},"Sigma-1 receptor agonist PRE084 is protective against mutant huntingtin-induced cell degeneration: involvement of calpastatin and the NF-κB pathway.","23703391",42]
["2,3-bis(2-hydroxyethylsulfanyl)-(1,4)naphthoquinone","2,3-bis(2-hydroxyethylsulfanyl)-(1,4)naphthoquinone","C451261","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25477201","Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression.","25477201",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C12803,B12803)","v":"2,4-Dichlorophenoxyacetic Acid"},"2,4-Dichlorophenoxyacetic Acid","D015084","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J12803,K12803)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,1,2016,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q12803,Q12803)","v":"25058513"},"Microbial degradation of 2,4-dichlorophenoxyacetic acid: Insight into the enzymes and catabolic genes involved, their regulation and biotechnological implications.","25058513",42]
["2,4-thiazolidinedione","2,4-thiazolidinedione","C089946","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9792555","Increased adipose expression of the uncoupling protein-3 gene by thiazolidinediones in Wistar fatty rats and in cultured adipocytes.","9792555",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C12931,B12931)","v":"25-hydroxycholesterol"},"25-hydroxycholesterol","C007997","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J12931,K12931)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,2,1994,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q12931,Q12931)","v":"8142309"},"Oxysterol sensitive and resistant lymphoid cells: correlation with regulation of cellular nucleic acid binding protein mRNA.","8142309",42]
["27-hydroxycholesterol","27-hydroxycholesterol","C076996","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9804848","Oxysterol regulation of steroidogenic acute regulatory protein gene expression. Structural specificity and transcriptional and posttranscriptional actions.","9804848",42]
["2-aminoacetophenone","2-aminoacetophenone","C055495","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"26935176","Bacterial-excreted small volatile molecule 2-aminoacetophenone induces oxidative stress and apoptosis in murine skeletal muscle.","26935176",42]
["2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid","2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid","C116817","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27771930","CDDO and Its Role in Chronic Diseases.","27771930",42]
["2-tert-butylhydroquinone","2-tert-butylhydroquinone","C018855","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11162512","Nrf2-dependent activation of the antioxidant responsive element by tert-butylhydroquinone is independent of oxidative stress in IMR-32 human neuroblastoma cells.","11162512",42]
["3-(4-methylphenylsulfonyl)-2-propenenitrile","3-(4-methylphenylsulfonyl)-2-propenenitrile","C434003","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"19913011","A noble function of BAY 11-7082: Inhibition of platelet aggregation mediated by an elevated cAMP-induced VASP, and decreased ERK2/JNK1 phosphorylations.","19913011",42]
["3,3'-diindolylmethane","3,3'-diindolylmethane","C016392","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"25816057","3,3'-Diindolylmethane attenuates cardiac H9c2 cell hypertrophy through 5'-adenosine monophosphate-activated protein kinase-α.","25816057",42]
["3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer","3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer","D019900","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15542756","Alpha 7-type nicotinic acetylcholine receptor and prodynorphin mRNA expression after administration of (-)-nicotine and U-50,488H in beta-amyloid peptide (25-35)-treated mice.","15542756",42]
["3-Hydroxybutyric Acid","3-Hydroxybutyric Acid","D020155","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23281705","Poly (3-hydroxybutyrate-co-3-hydroxyhexanoate)/collagen hybrid scaffolds for tissue engineering applications.","23281705",42]
["3-nitropropionic acid","3-nitropropionic acid","C015392","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15372497","Influence of chemical and ischemic preconditioning on cytokine expression after focal brain ischemia.","15372497",42]
["4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine","4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine","C000616266","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27388143","Inhibition of human equilibrative nucleoside transporters by 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine.","27388143",42]
["4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione","4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione","C494356","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25453207","Activation of AKT/GSK3β pathway by TDZD-8 attenuates kainic acid induced neurodegeneration but not seizures in mice.","25453207",42]
["4-Butyrolactone","4-Butyrolactone","D015107","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26550952","Bromo-honaucin A inhibits osteoclastogenic differentiation in RAW 264.7 cells via Akt and ERK signaling pathways.","26550952",42]
["4-epianhydrotetracycline","4-epianhydrotetracycline","C016229","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11713335","Modulation of myosin A expression by a newly established tetracycline repressor-based inducible system in Toxoplasma gondii.","11713335",42]
["4-hydroxy-2-nonenal","4-hydroxy-2-nonenal","C027576","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23726997","High-fat diet induces changes in adipose tissue trans-4-oxo-2-nonenal and trans-4-hydroxy-2-nonenal levels in a depot-specific manner.","23726997",42]
["4-octylphenol","4-octylphenol","C080417","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"11882478","Octylphenol (OP) alters the expression of members of the amyloid protein family in the hypothalamus of the snapping turtle, Chelydra serpentina serpentina.","11882478",42]
["4-vinyl-1-cyclohexene dioxide","4-vinyl-1-cyclohexene dioxide","C012606","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15710172","Differences between rats and mice in the involvement of the aryl hydrocarbon receptor in 4-vinylcyclohexene diepoxide-induced ovarian follicle loss.","15710172",42]
["5,8-dihydroxy-10-methoxy-2-propylbenzo(h)chromen-4-one","5,8-dihydroxy-10-methoxy-2-propylbenzo(h)chromen-4-one","C000597663","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"25230122","Anti-inflammatory and analgesic effects of the marine-derived compound comaparvin isolated from the crinoid Comanthus bennetti.","25230122",42]
["5-diphosphomevalonic acid","5-diphosphomevalonic acid","C046285","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26055626","Disruption of the mevalonate pathway induces dNTP depletion and DNA damage.","26055626",42]
["5-Methylcytosine","5-Methylcytosine","D044503","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1982,"6756802","Is DNA methylation responsible for mammalian X chromosome inactivation?","6756802",42]
["6-((3-((dimethylamino)carbonyl)phenyl)sulfonyl)-8-methyl-4-((3-methyloxyphenyl)amino)-3-quinolinecarboxamide","6-((3-((dimethylamino)carbonyl)phenyl)sulfonyl)-8-methyl-4-((3-methyloxyphenyl)amino)-3-quinolinecarboxamide","C549469","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27731313","Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody-drug Conjugate.","27731313",42]
["6-hydroxy-10-chlorobenzo(c)quinolizinium","6-hydroxy-10-chlorobenzo(c)quinolizinium","C451901","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17197571","MPB-07 reduces the inflammatory response to Pseudomonas aeruginosa in cystic fibrosis bronchial cells.","17197571",42]
["7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide","7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide","D015123","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16645724","Involvement of nuclear factor of activated T cells 3 (NFAT3) in cyclin D1 induction by B[a]PDE or B[a]PDE and ionizing radiation in mouse epidermal Cl 41 cells.","16645724",42]
["8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid","8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid","C581236","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28153881","Prevention of Diet-Induced Metabolic Dysregulation, Inflammation, and Atherosclerosis in Ldlr-/- Mice by Treatment With the ATP-Citrate Lyase Inhibitor Bempedoic Acid.","28153881",42]
["9,10-Dimethyl-1,2-benzanthracene","9,10-Dimethyl-1,2-benzanthracene","D015127","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"25448685","Enhanced susceptibility of ovaries from obese mice to 7,12-dimethylbenz[a]anthracene-induced DNA damage.","25448685",42]
["A 285222","A 285222","C494244","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"25583579","Streptococcal M1 protein triggers chemokine formation, neutrophil infiltration, and lung injury in an NFAT-dependent manner.","25583579",42]
["Abscisic Acid","Abscisic Acid","D000040","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1991,"1827067","An ABA and GA modulated gene expressed in the barley embryo encodes an aldose reductase related protein.","1827067",42]
["Acetaldehyde","Acetaldehyde","D000079","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2000,"10613735","Hydrogen peroxide: a link between acetaldehyde-elicited alpha1(I) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells.","10613735",42]
["Acetaminophen","Acetaminophen","D000082","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2008,"18467506","Stem cell factor and c-kit are involved in hepatic recovery after acetaminophen-induced liver injury in mice.","18467506",42]
["Acetaminophen","Acetaminophen","D000082","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25687687","Application of IL-36 receptor antagonist weakens CCL20 expression and impairs recovery in the late phase of murine acetaminophen-induced liver injury.","25687687",42]
["Acetylcarnitine","Acetylcarnitine","D000108","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1994,"8187841","Acetyl-L-carnitine treatment increases nerve growth factor levels and choline acetyltransferase activity in the central nervous system of aged rats.","8187841",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18621107","Involvement of angiotensin converting enzyme in cerebral hypoperfusion induced anterograde memory impairment and cholinergic dysfunction in rats.","18621107",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28137966","Loss of M1 Receptor Dependent Cholinergic Excitation Contributes to mPFC Deactivation in Neuropathic Pain.","28137966",42]
["Acetylglucosamine","Acetylglucosamine","D000117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22578178","Anti-allergic activity of crystallinity controlled N-acetyl glucosamine.","22578178",42]
["Aconitine","Aconitine","D000157","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"27766701","Alpha-7 nicotinic acetylcholine receptor (nAChR) agonist inhibits the development of endometriosis by regulating inflammation.","27766701",42]
["Adamantane","Adamantane","D000218","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23603201","Saxagliptin: a dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease.","23603201",42]
["Adenine","Adenine","D000225","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15955869","Increased Bcl2 expression by antisense oligoribonucleotides targeting the adenine-uridine-rich element motif.","15955869",42]
["afimoxifene","afimoxifene","C016601","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1995,"7478619","Expression of cyclin D1 mRNA is not upregulated by Myc in rat fibroblasts.","7478619",42]
["AG 1879","AG 1879","C412373","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20437588","Blood-brain barrier breakdown and repair by Src after thrombin-induced injury.","20437588",42]
["Albendazole","Albendazole","D015766","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19481175","In vitro resistance to 5-nitroimidazoles and benzimidazoles in Giardia duodenalis: variability and variation in gene expression.","19481175",42]
["alginic acid","alginic acid","C008970","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"21360689","Gene expression of alginate-embedded chondrocyte subpopulations and their response to exogenous IGF-1 delivery.","21360689",42]
["alitretinoin","alitretinoin","C103303","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17464174","p38 MAPK and ERK activation by 9-cis-retinoic acid induces chemokine receptors CCR1 and CCR2 expression in human monocytic THP-1 cells.","17464174",42]
["alpha antigens, Mycobacterium","alpha antigens, Mycobacterium","C052242","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1988,"2842287","Cloning and expression of the Mycobacterium bovis BCG gene for extracellular alpha antigen.","2842287",42]
["alpha-ketoglutaric acid","alpha-ketoglutaric acid","C029743","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28398002","Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction.","28398002",42]
["alpha-Tocopherol","alpha-Tocopherol","D024502","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22537979","Deltamethrin-induced oxidative stress and biochemical changes in tissues and blood of catfish (Clarias gariepinus): antioxidant defense and role of alpha-tocopherol.","22537979",42]
["aluminum chloride","aluminum chloride","C010845","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1994,"7804601","Dose-dependent selective suppression of light (NFL) and medium (NFM) but not heavy (NFH) molecular weight neurofilament mRNA levels in acute aluminum neurotoxicity.","7804601",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C15363,B15363)","v":"Ambroxol"},"Ambroxol","D000551","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J15363,K15363)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,2,2014,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q15363,Q15363)","v":"24574503"},"Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells.","24574503",42]
["Aminoethylphosphonic Acid","Aminoethylphosphonic Acid","D000615","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23434798","Probing a coral genome for components of the  photoprotective scytonemin biosynthetic pathway and the 2-aminoethylphosphonate pathway.","23434798",42]
["Amiodarone","Amiodarone","D000638","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"18020914","Amiodarone reversibly decreases sodium-iodide symporter mRNA expression at therapeutic concentrations and induces antioxidant responses at supraphysiological concentrations in cultured human thyroid follicles.","18020914",42]
["Ammonia","Ammonia","D000641","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1989,"2504448","The effect of ammonia on cell-type-specific enzyme accumulation in Dictyostelium discoideum.","2504448",42]
["amorphastilbol","amorphastilbol","C575104","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23376064","Anti-diabetic effect of amorphastilbol through PPARα/γ dual activation in db/db mice.","23376064",42]
["Amphetamine","Amphetamine","D000661","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17658493","Acute amphetamine treatment decreases the expression of 180-200 kDa isoform of polysialic acid linked neural cell adhesion molecule in mouse hippocampus.","17658493",42]
["anacetrapib","anacetrapib","C530884","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23958252","Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib in Japanese patients with dyslipidemia.","23958252",42]
["anatoxin a","anatoxin a","C509783","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15862019","[The immediate early genes expression in the PC12 cells activated by anatoxin-a].","15862019",42]
["Anthralin","Anthralin","D000875","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11235021","Dithranol upregulates IL-10 receptors on the cultured human keratinocyte cell line HaCaT.","11235021",42]
["anthrax toxin","anthrax toxin","C030325","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"26912657","Inhibition of Interleukin 1β (IL-1β) Expression by Anthrax Lethal Toxin (LeTx) Is Reversed by Histone Deacetylase 8 (HDAC8) Inhibition in Murine Macrophages.","26912657",42]
["Apigenin","Apigenin","D047310","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27976636","Intraperitoneal administration of apigenin in liver ischemia/reperfusion injury protective effects.","27976636",42]
["Arabinose","Arabinose","D001089","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20525212","Integration of transcriptional inputs at promoters of the arabinose catabolic pathway.","20525212",42]
["Arachidonic Acid","Arachidonic Acid","D016718","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20093140","Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases.","20093140",42]
["Arachidonic Acid","Arachidonic Acid","D016718","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27747453","Dietary Arachidonic Acid Has a Time-Dependent Differential Impact on Adipogenesis Modulated via COX and LOX Pathways in Grass Carp Ctenopharyngodon idellus.","27747453",42]
["arsenic trioxide","arsenic trioxide","C006632","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17258074","An approach to elucidate potential mechanism of renal toxicity of arsenic trioxide.","17258074",42]
["arsenite","arsenite","C015001","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18182400","Positive signaling interactions between arsenic and ethanol for angiogenic gene induction in human microvascular endothelial cells.","18182400",42]
["artemether","artemether","C032942","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"22615315","In vitro-reduced susceptibility to artemether in P. falciparum and its association with polymorphisms on transporter genes.","22615315",42]
["Asbestos, Serpentine","Asbestos, Serpentine","D017632","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1988,"2845418","Asbestos fibers mediate transformation of monkey cells by exogenous plasmid DNA.","2845418",42]
["ascorbate-2-phosphate","ascorbate-2-phosphate","C011669","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"25193867","Dietary ascorbic acid modulates the expression profile of stress protein genes in hepatopancreas of adult Pacific abalone Haliotis discus hannai Ino.","25193867",42]
["Ascorbic Acid","Ascorbic Acid","D001205","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23415019","Sodium-coupled vitamin C transporter (SVCT2): expression, function, and regulation in intervertebral disc cells.","23415019",42]
["ascorbyl 3-p-coumarate","ascorbyl 3-p-coumarate","C000607982","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26078014","Ascorbyl coumarates as multifunctional cosmeceutical agents that inhibit melanogenesis and enhance collagen synthesis.","26078014",42]
["Aspirin","Aspirin","D001241","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15978173","Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats.","15978173",42]
["astragaloside A","astragaloside A","C052064","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27395045","Astragaloside IV Inhibits the Inflammatory Injury of Chicken Type II Pneumocytes Induced by Avian Pathogenic Escherichia coli.","27395045",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"17186993","Differential impact of atorvastatin vs pravastatin on progressive insulin resistance and left ventricular diastolic dysfunction in a rat model of type II diabetes.","17186993",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"21796806","Effects of atorvastatin on progression of diabetic nephropathy and local RAGE and soluble RAGE expressions in rats.","21796806",42]
["Aurintricarboxylic Acid","Aurintricarboxylic Acid","D001312","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"12112649","DNA transfection of macaque and murine respiratory tissue is greatly enhanced by use of a nuclease inhibitor.","12112649",42]
["Azithromycin","Azithromycin","D017963","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"22577246","Azithromycin inhibits mucus hypersecretion from airway epithelial cells.","22577246",42]
["Baclofen","Baclofen","D001418","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1997,"9152404","An antisense oligonucleotide on the mouse Shaker-like potassium channel Kv1.1 gene prevents antinociception induced by morphine and baclofen.","9152404",42]
["bavachalcone","bavachalcone","C508227","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18433733","Bavachalcone inhibits osteoclast differentiation through suppression of NFATc1 induction by RANKL.","18433733",42]
["benphothiamine","benphothiamine","C013835","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2009,"19768736","Thiamine and benfotiamine prevent apoptosis induced by high glucose-conditioned extracellular matrix in human retinal pericytes.","19768736",42]
["Benzene","Benzene","D001554","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"25447454","Metabolic polymorphisms and biomarkers of effect in the biomonitoring of occupational exposure to low-levels of benzene: state of the art.","25447454",42]
["Benzo(a)pyrene","Benzo(a)pyrene","D001564","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20064835","Transcriptional signature of human macrophages exposed to the environmental contaminant benzo(a)pyrene.","20064835",42]
["benzoyl bromide","benzoyl bromide","C009852","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24450937","Exploring the formation and recognition of an important G-quadruplex in a HIF1α promoter and its transcriptional inhibition by a benzo[c]phenanthridine derivative.","24450937",42]
["Berberine","Berberine","D001599","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20410605","Selective regulation of multidrug resistance protein in vascular smooth muscle cells by the isoquinoline alkaloid coptisine.","20410605",42]
["Berberine","Berberine","D001599","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26166377","Berberine inhibits tumor necrosis factor-α-induced expression of inflammatory molecules and activation of nuclear factor-κB via the activation of AMPK in vascular endothelial cells.","26166377",42]
["beta Carotene","beta Carotene","D019207","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15962303","beta-cryptoxanthin stimulates cell differentiation and mineralization in osteoblastic MC3T3-E1 cells.","15962303",42]
["Betaine","Betaine","D001622","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28592272","Betaine promotes cell differentiation of human osteoblasts in primary culture.","28592272",42]
["beta-Naphthoflavone","beta-Naphthoflavone","D019324","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2000,"11460681","Lack of effect of beta-naphthoflavone on induction of Nramp genes in adult rainbow trout Oncorhynchus mykiss.","11460681",42]
["beta-tricalcium phosphate","beta-tricalcium phosphate","C485817","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24408878","PDLLA/PRGD/β-TCP conduits build the neurotrophin-rich microenvironment suppressing the oxidative stress and promoting the sciatic nerve regeneration.","24408878",42]
["Bezafibrate","Bezafibrate","D001629","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1995,"7867641","Evidence for transcriptional induction of the liver fatty-acid-binding-protein gene by bezafibrate in the small intestine.","7867641",42]
["Biopterin","Biopterin","D001708","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2005,"15935064","Long-term glial cell line-derived neurotrophic factor overexpression in the intact nigrostriatal system in rats leads to a decrease of dopamine and increase of tetrahydrobiopterin production.","15935064",42]
["Biotin","Biotin","D001710","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20655901","Pharmacological concentrations of biotin reduce serum triglycerides and the expression of lipogenic genes.","20655901",42]
["bis(tri-n-butyltin)oxide","bis(tri-n-butyltin)oxide","C005961","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"17942131","Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening.","17942131",42]
["bisphenol A","bisphenol A","C006780","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15738621","Effects of in utero exposure to bisphenol A on mRNA expression of arylhydrocarbon and retinoid receptors in murine embryos.","15738621",42]
["bisphenol A","bisphenol A","C006780","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2018,"29680376","Bisphenol A and Estradiol Impede Myoblast Differentiation through Down-Regulating Akt Signaling Pathway.","29680376",42]
["Blood Glucose","Blood Glucose","D001786","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2003,"12828825","Hepatic gene expression profiling of streptozotocin-induced diabetes.","12828825",42]
["Blood Glucose","Blood Glucose","D001786","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19474328","Relationship among brain and blood glucose levels and spontaneous and glucoprivic feeding.","19474328",42]
["Blood Glucose","Blood Glucose","D001786","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"22445099","Endothelial progenitor cell function inversely correlates with long-term glucose control in diabetic patients: association with the attenuation of the heme oxygenase-adiponectin axis.","22445099",42]
["BmK Ita1 toxin, Buthus martensii","BmK Ita1 toxin, Buthus martensii","C471081","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2003,"12721493","Cloning, co-expression with an amidating enzyme, and activity of the scorpion toxin BmK ITa1 cDNA in insect cells.","12721493",42]
["Bortezomib","Bortezomib","D000069286","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22516063","Attenuation of early atherogenesis in low-density lipoprotein receptor-deficient mice by proteasome inhibition.","22516063",42]
["Brefeldin A","Brefeldin A","D020126","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2003,"12548716","Brefeldin A-induced neurotoxicity in cultured spinal cord neurons.","12548716",42]
["Bumetanide","Bumetanide","D002034","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28152000","Bumetanide increases Cl--dependent short-circuit current in late distal colon: Evidence for the presence of active electrogenic Cl- absorption.","28152000",42]
["butenolide","butenolide","C004511","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20827734","Changes in the proteome and phosphoproteome expression in the bryozoan Bugula neritina larvae in response to the antifouling agent butenolide.","20827734",42]
["Butyric Acid","Butyric Acid","D020148","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2003,"12619895","Antiangiogenic effects of butyric acid involve inhibition of VEGF/KDR gene expression and endothelial cell proliferation.","12619895",42]
["Butyric Acid","Butyric Acid","D020148","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25700826","Sodium butyrate-induced histone hyperacetylation up-regulating WT1 expression in porcine kidney fibroblasts.","25700826",42]
["Cadaverine","Cadaverine","D002103","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1985,"3937520","Gene expression of ornithine decarboxylase in L1210 leukaemia cells exposed to DL-2-difluoromethylornithine in the presence of cadaverine.","3937520",42]
["Cadmium Chloride","Cadmium Chloride","D019256","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1989,"2478139","Evidence for the participation of topoisomerases I and II in cadmium-induced metallothionein expression in Chinese hamster ovary cells.","2478139",42]
["caffeic acid","caffeic acid","C040048","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"11734336","Caffeic acid phenethyl ester inhibits nitric oxide synthase gene expression and enzyme activity.","11734336",42]
["Caffeine","Caffeine","D002110","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19291178","Identification of paraxanthine as the most potent caffeine-derived inhibitor of connective tissue growth factor expression in liver parenchymal cells.","19291178",42]
["Calcifediol","Calcifediol","D002112","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28199350","25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression.","28199350",42]
["Calcitriol","Calcitriol","D002117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1999,"10218975","Positive and negative regulations of the renal 25-hydroxyvitamin D3 1alpha-hydroxylase gene by parathyroid hormone, calcitonin, and 1alpha,25(OH)2D3 in intact animals.","10218975",42]
["Calcitriol","Calcitriol","D002117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11502592","Vitamin D reduces renal NaPi-2 in PTH-infused rats: complexity of vitamin D action on renal P(i) handling.","11502592",42]
["Calcitriol","Calcitriol","D002117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1991,"1661008","Molecular biology and vitamin D function.","1661008",42]
["Calcitriol","Calcitriol","D002117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19144406","Synergistic induction of gene expression during the differentiation into mature macrophage in human myeloblastic leukemia cells treated with TPA and KH1060.","19144406",42]
["Calcitriol","Calcitriol","D002117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21424825","Differential effects of vitamin d receptor agonists on gene expression in neonatal rat cardiomyocytes.","21424825",42]
["Calcitriol","Calcitriol","D002117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23413544","Antibiotic-like actions of vitamin D.","23413544",42]
["Calcitriol","Calcitriol","D002117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27181168","Calcitriol prevents inflammatory gene expression in macrovascular endothelial cells.","27181168",42]
["Calcitriol","Calcitriol","D002117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1988,"3347623","Cooperative effect of thyroid hormones and vitamin D on intestinal calcium and phosphate transport.","3347623",42]
["Calcitriol","Calcitriol","D002117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1994,"7986828","Vitamin D-dependent rickets type II: regulation of human osteocalcin gene expression in cells with defective vitamin D receptors by 1,25-dihydroxyvitamin D-3, retinoic acid, and triiodothyronine.","7986828",42]
["Calcitriol","Calcitriol","D002117","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1996,"8883952","Demonstration of a second pharmacologically active promoter region in the NGF gene that induces transcription at exon 3.","8883952",42]
["calcium phosphate","calcium phosphate","C020243","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"24889783","Bone morphogenetic protein Smads signaling in mesenchymal stem cells affected by osteoinductive calcium phosphate ceramics.","24889783",42]
["Calcium Sulfate","Calcium Sulfate","D002133","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21781446","Calcium sulfate stimulates pulp stem cells towards osteoblasts differentiation.","21781446",42]
["Calcium, Dietary","Calcium, Dietary","D002136","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26441239","A High-Calcium and Phosphate Rescue Diet and VDR-Expressing Transgenes Normalize Serum Vitamin D Metabolite Profiles and Renal Cyp27b1 and Cyp24a1 Expression in VDR Null Mice.","26441239",42]
["Camptothecin","Camptothecin","D002166","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"22194537","Neurodevelopmental disorders. New hope for a devastating neurological disorder.","22194537",42]
["Caprolactam","Caprolactam","D002209","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25710252","Roles of hydroxyapatite allocation and microgroove dimension in promoting preosteoblastic cell functions on photocured polymer nanocomposites through nuclear distribution and alignment.","25710252",42]
["Capsaicin","Capsaicin","D002211","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24139494","Capsaicin treatment reduces nasal hyperreactivity and transient receptor potential cation channel subfamily V, receptor 1 (TRPV1) overexpression in patients with idiopathic rhinitis.","24139494",42]
["Carbachol","Carbachol","D002217","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9815108","Galphai-2 is required for carbachol-induced stress fiber formation in human airway smooth muscle cells.","9815108",42]
["Carbon Dioxide","Carbon Dioxide","D002245","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"25216596","Gene expression profiling in gills of the great spider crab Hyas araneus in response to ocean acidification and warming.","25216596",42]
["Carbon Monoxide","Carbon Monoxide","D002248","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24442266","Anti-inflammatory effects of carbon monoxide-releasing molecule on trinitrobenzene sulfonic acid-induced colitis in mice.","24442266",42]
["Carbon Monoxide","Carbon Monoxide","D002248","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1997,"9118487","Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells.","9118487",42]
["Carbon Tetrachloride","Carbon Tetrachloride","D002251","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"20865324","Hepatoprotective and antioxidant effects of Glycyrrhiza glabra extract against carbon tetrachloride (CCl(4))-induced hepatocyte damage in common carp (Cyprinus carpio).","20865324",42]
["Carnitine","Carnitine","D002331","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18801379","Mildronate decreases carnitine availability and up-regulates glucose uptake and related gene expression in the mouse heart.","18801379",42]
["Carnitine","Carnitine","D002331","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28139067","The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice.","28139067",42]
["carvedilol","carvedilol","C043211","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19478468","Carvedilol ameliorates the decreases in connexin 43 and ventricular fibrillation threshold in rats with myocardial infarction.","19478468",42]
["Catechin","Catechin","D002392","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2003,"12695518","The antioxidant (-)-epigallocatechin-3-gallate inhibits rat hepatic stellate cell proliferation in vitro by blocking the tyrosine phosphorylation and reducing the gene expression of platelet-derived growth factor-beta receptor.","12695518",42]
["Catechin","Catechin","D002392","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"21829010","Catechin-rich grape seed extract supplementation attenuates diet-induced obesity in C57BL/6J mice.","21829010",42]
["Catechin","Catechin","D002392","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25343566","Critical role of prohibitin in endothelial cell apoptosis caused by glycated low-density lipoproteins and protective effects of grape seed procyanidin B2.","25343566",42]
["Catechin","Catechin","D002392","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"27473778","Prevention of abdominal aortic aneurysm progression by oral administration of green tea polyphenol in a rat model.","27473778",42]
["CD226 antigen","CD226 antigen","C108133","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2006,"16547212","Comment on \"CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions\".","16547212",42]
["CD3 Complex","CD3 Complex","D017252","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2008,"18672004","Tumor-derived soluble MICs impair CD3(+)CD56(+) NKT-like cell cytotoxicity in cancer patients.","18672004",42]
["CD3 Complex","CD3 Complex","D017252","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"24098453","Zfat-deficiency results in a loss of CD3ζ phosphorylation with dysregulation of ERK and Egr activities leading to impaired positive selection.","24098453",42]
["CD3 Complex","CD3 Complex","D017252","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1997,"9344703","Signals transduced through the CD4 molecule interfere with TCR/CD3-mediated ras activation leading to T cell anergy/apoptosis.","9344703",42]
["Celecoxib","Celecoxib","D000068579","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"22967986","Effectiveness of cyclooxygenase-2 inhibition in limiting abdominal aortic aneurysm progression in mice correlates with a differentiated smooth muscle cell phenotype.","22967986",42]
["ceramide 1-phosphate","ceramide 1-phosphate","C065576","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"21111813","Ceramide kinase: the first decade.","21111813",42]
["Chalcone","Chalcone","D002599","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"25337218","Effects of hydroxysafflor yellow A on proliferation and collagen synthesis of rat vascular adventitial fibroblasts induced by angiotensin II.","25337218",42]
["Chenodeoxycholic Acid","Chenodeoxycholic Acid","D002635","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23767959","Diacylglycerol kinase θ couples farnesoid X receptor-dependent bile acid signalling to Akt activation and glucose homoeostasis in hepatocytes.","23767959",42]
["Chitosan","Chitosan","D048271","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22790025","Chitosan and Chitin Hexamers affect expansion and differentiation of mesenchymal stem cells differently.","22790025",42]
["Chloral Hydrate","Chloral Hydrate","D002697","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"21932367","Dynamic loss of surface-expressed AMPA receptors in mouse cortical and striatal neurons during anesthesia.","21932367",42]
["Chlorogenic Acid","Chlorogenic Acid","D002726","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23146752","Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway.","23146752",42]
["Chlorogenic Acid","Chlorogenic Acid","D002726","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28407238","Quercetin, Hyperin, and Chlorogenic Acid Improve Endothelial Function by Antioxidant, Antiinflammatory, and ACE Inhibitory Effects.","28407238",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C20675,B20675)","v":"Chlorpromazine"},"Chlorpromazine","D002746","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J20675,K20675)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,2,2002,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q20675,Q20675)","v":"11839208"},"Low concentrations of chlorpromazine and related phenothiazines stimulate gene transfer in HeLa cells via receptor-mediated endocytosis.","11839208",42]
["Chlorpyrifos","Chlorpyrifos","D004390","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26079056","Chlorpyrifos is estrogenic and alters embryonic hatching, cell proliferation and apoptosis in zebrafish.","26079056",42]
["Cholecalciferol","Cholecalciferol","D002762","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1990,"1965647","Effect of 1,25-(OH)2-vitamin D3 on growth, homologous receptor and c-myc regulation in C3H/10T1/2 cells.","1965647",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2000,"10809236","Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha.","10809236",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2002,"12205026","The fetal origins of atherosclerosis: maternal hypercholesterolemia, and cholesterol-lowering or antioxidant treatment during pregnancy influence in utero programming and postnatal susceptibility to atherogenesis.","12205026",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"14698043","Statins upregulate CD36 expression in human monocytes, an effect strengthened when combined with PPAR-gamma ligands Putative contribution of Rho GTPases in statin-induced CD36 expression.","14698043",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1992,"1563548","[Nutritional regulation of apolipoprotein genes. Effect of dietary carbohydrates and fatty acids].","1563548",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"17440045","Regulation of hepatic Insig-2 by the farnesoid X receptor.","17440045",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18095660","Novel transcriptional activities of vitamin E: inhibition of cholesterol biosynthesis.","18095660",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19296549","Plasma proteome analysis for anti-obesity and anti-diabetic potentials of chitosan oligosaccharides in ob/ob mice.","19296549",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20441669","The hypocholesterolaemic effects of Lactobacillus acidophilus American type culture collection 4356 in rats are mediated by the down-regulation of Niemann-Pick C1-like 1.","20441669",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"22234859","Membrane phospholipid asymmetry counters the adverse effects of sterol overloading in the Golgi membrane of Drosophila.","22234859",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23204179","The expression of cholesterol metabolism genes in monocytes from HIV-infected subjects suggests intracellular cholesterol accumulation.","23204179",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23748774","Effect of licorice flavonoid oil on cholesterol metabolism in high fat diet rats.","23748774",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24719886","Omega-3 fatty acid enriched chevon (goat meat) lowers plasma cholesterol levels and alters gene expressions in rats.","24719886",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27063951","Ursolic acid enhances macrophage autophagy and attenuates atherogenesis.","27063951",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27648945","Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets.","27648945",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28697173","Modulating cancer cell survival by targeting intracellular cholesterol transport.","28697173",42]
["cholesterol hydroperoxide","cholesterol hydroperoxide","C002843","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23467407","Deleterious cholesterol hydroperoxide trafficking in steroidogenic acute regulatory (StAR) protein-expressing MA-10 Leydig cells: implications for oxidative stress-impaired steroidogenesis.","23467407",42]
["Cholesterol, Dietary","Cholesterol, Dietary","D002791","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"27863346","A diet-induced Sprague-Dawley rat model of nonalcoholic steatohepatitis-related cirrhosis.","27863346",42]
["Choline","Choline","D002794","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23195033","A higher maternal choline intake among third-trimester pregnant women lowers placental and circulating concentrations of the antiangiogenic factor fms-like tyrosine kinase-1 (sFLT1).","23195033",42]
["Chondroitin","Chondroitin","D002807","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2005,"16118286","Regulation of the chondroitin/dermatan fine structure by transforming growth factor-beta1 through effects on polymer-modifying enzymes.","16118286",42]
["cinnamic aldehyde","cinnamic aldehyde","C012843","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28719892","Cinnamaldehyde Ameliorates Diet-Induced Obesity in Mice by Inducing Browning of White Adipose Tissue.","28719892",42]
["Cisplatin","Cisplatin","D002945","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"12494868","Effect of cisplatin treatment on early activation of oncogenes in vivo.","12494868",42]
["Cisplatin","Cisplatin","D002945","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18656965","Integrated pathway analysis of rat urine metabolic profiles and kidney transcriptomic profiles to elucidate the systems toxicology of model nephrotoxicants.","18656965",42]
["Cisplatin","Cisplatin","D002945","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"25272046","Long-term aerobic exercise protects against cisplatin-induced nephrotoxicity by modulating the expression of IL-6 and HO-1.","25272046",42]
["Citalopram","Citalopram","D015283","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23583029","Additional ECT increases BDNF-levels in patients suffering from major depressive disorders compared to patients treated with citalopram only.","23583029",42]
["clematichinenoside","clematichinenoside","C581539","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25463279","Clematichinenoside inhibits VCAM-1 and ICAM-1 expression in TNF-α-treated endothelial cells via NADPH oxidase-dependent IκB kinase/NF-κB pathway.","25463279",42]
["Clodronic Acid","Clodronic Acid","D004002","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11172684","A combination of subtherapeutic doses of chemically modified doxycycline (CMT-8) and a bisphosphonate (clodronate) inhibits bone loss in the ovariectomized rat: a dynamic histomorphometric and gene expression study.","11172684",42]
["Clozapine","Clozapine","D003024","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11180499","FosB in rat striatum: normal regional distribution and enhanced expression after 6-month haloperidol administration.","11180499",42]
["Clozapine","Clozapine","D003024","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1996,"9118313","Differential regulation of hippocampal AMPA and kainate receptor subunit expression by haloperidol and clozapine.","9118313",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2002,"12062568","Effects of prenatal cocaine exposure on latent inhibition in 1-year-old female rats.","12062568",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"14745842","Microarray profile analysis of toxic cocaine-induced alterations in the expression of mouse brain gene sequences: a possible 'protective' effect of buprenorphine.","14745842",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"19666831","Deletion of CREB1 from the dorsal telencephalon reduces motivational properties of cocaine.","19666831",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"22072669","Integrins modulate relapse to cocaine-seeking.","22072669",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25698746","SIRT1-FOXO3a regulate cocaine actions in the nucleus accumbens.","25698746",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1994,"8301594","Neural and endocrine mechanisms of cocaine-induced 70-kDa heat shock protein expression in aorta and adrenal gland.","8301594",42]
["Colchicine","Colchicine","D003078","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"18063853","The effect of all-trans retinoic acid and/or colchicine on expression of rexinoid and thyroid hormone nuclear receptors and their coregulators in primary rat hepatocytes.","18063853",42]
["Colforsin","Colforsin","D005576","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1990,"1704320","Forskolin down-regulates type-1 plasminogen activator inhibitor and tissue-type plasminogen activator and their mRNAs in human fibrosarcoma cells.","1704320",42]
["Congo Red","Congo Red","D003224","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"17441503","Pathogenic chaperone-like RNA induces congophilic aggregates and facilitates neurodegeneration in Drosophila.","17441503",42]
["Copper Sulfate","Copper Sulfate","D019327","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1993,"8276774","Regulation of hsp70 synthesis induced by cupric sulfate and zinc sulfate in thermotolerant HeLa cells.","8276774",42]
["cudraflavone B","cudraflavone B","C542041","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"25061726","Cudarflavone B provides neuroprotection against glutamate-induced mouse hippocampal HT22 cell damage through the Nrf2 and PI3K/Akt signaling pathways.","25061726",42]
["Curcumin","Curcumin","D003474","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16807698","The antioxidants curcumin and quercetin inhibit inflammatory processes associated with arthritis.","16807698",42]
["Curcumin","Curcumin","D003474","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18719352","Curcumin inhibits osteoclastogenesis by decreasing receptor activator of nuclear factor-kappaB ligand (RANKL) in bone marrow stromal cells.","18719352",42]
["Curcumin","Curcumin","D003474","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21906467","[Effect of curcumin on IL-17-induced nitric oxide production and expression of iNOS in human keratinocytes].","21906467",42]
["Curcumin","Curcumin","D003474","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25867253","Curcumin inhibits apoptosis and brain edema induced by hypoxia-hypercapnia brain damage in rat models.","25867253",42]
["Curcumin","Curcumin","D003474","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"27743775","Curcumin as a natural regulator of monocyte chemoattractant protein-1.","27743775",42]
["curdlan","curdlan","C038459","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25965065","Not Just a Sum? Identifying Different Types of Interplay between Constituents in Combined Interventions.","25965065",42]
["Cycloheximide","Cycloheximide","D003513","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1989,"2475762","[Expression of oncogenes in the rat liver under conditions of template biosynthesis uncoupling by sublethal doses of cycloheximide].","2475762",42]
["Cyclophosphamide","Cyclophosphamide","D003520","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23791611","The changes induced by cyclophosphamide in intestinal barrier and microflora in mice.","23791611",42]
["cylindrospermopsin","cylindrospermopsin","C089595","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23726867","Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells.","23726867",42]
["Cytochalasin B","Cytochalasin B","D003571","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1991,"2019601","Substitution of leucine for tryptophan 412 does not abolish cytochalasin B labeling but markedly decreases the intrinsic activity of GLUT1 glucose transporter.","2019601",42]
["Cytosine","Cytosine","D003596","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"27356509","In vivo genome-wide profiling reveals a tissue-specific role for 5-formylcytosine.","27356509",42]
["Cytosine","Cytosine","D003596","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1982,"6927792","Topographical distribution of 5-methylcytosine in animal and plant DNA.","6927792",42]
["daidzein","daidzein","C004742","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17655901","Isoflavonoid-based bone-sparing treatments exert a low activity on reproductive organs and on hepatic metabolism of estradiol in ovariectomized rats.","17655901",42]
["Daunorubicin","Daunorubicin","D003630","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1995,"7646548","Influx of daunorubicin in multidrug resistant Ehrlich ascites tumour cells: correlation to expression of P-glycoprotein and efflux. Influence of verapamil.","7646548",42]
["decamethrin","decamethrin","C017180","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20143453","Splice variant specific increase in Ca2+/calmodulin-dependent protein kinase 1-gamma mRNA expression in response to acute pyrethroid exposure.","20143453",42]
["Deferoxamine","Deferoxamine","D003676","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17329595","Regulation of gene expression in bovine blastocysts in response to oxygen and the iron chelator desferrioxamine.","17329595",42]
["delta(12)-prostaglandin J(2)","delta(12)-prostaglandin J(2)","C499810","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15713689","Stimulation of NGF expression and secretion in 3T3-L1 adipocytes by prostaglandins PGD2, PGJ2, and Delta12-PGJ2.","15713689",42]
["deoxynivalenol","deoxynivalenol","C007262","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23100596","Deoxynivalenol and E.coli lipopolysaccharide alter epithelial proliferation and spatial distribution of apical junction proteins along the small intestinal axis.","23100596",42]
["Desipramine","Desipramine","D003891","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16293366","Chronic antidepressant treatment modulates the release of somatostatin in the rat nucleus accumbens.","16293366",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1999,"10384181","Exogenous control of cardiac gene therapy: evidence of regulated myocardial transgene expression after adenovirus and adeno-associated virus transfer of expression cassettes containing corticosteroid response element promoters.","10384181",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2000,"11129600","Induction of osteopontin gene expression during mammary gland involution and effects of glucocorticoid on its expression in mammary epithelial cells.","11129600",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2003,"14566398","Synergistic regulation of the acute phase protein SIP24/24p3 by glucocorticoid and pro-inflammatory cytokines.","14566398",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15710351","Inhibition of tristetraprolin expression by dexamethasone in activated macrophages.","15710351",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16988013","Analysis of the dissociated steroid RU24858 does not exclude a role for inducible genes in the anti-inflammatory actions of glucocorticoids.","16988013",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"17541935","Glucocorticoid induced expression of connective tissue growth factor contributes to lactogenic differentiation of mouse mammary epithelial cells.","17541935",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"21928335","Dexamethasone indirectly induces Ndrg2 expression in rat astrocytes.","21928335",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21385937","Dynamic regulation of PDX-1 and FoxO1 expression by FoxA2 in dexamethasone-induced pancreatic β-cells dysfunction.","21385937",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1990,"2354997","Molecular characterization and acute phase expression of the multiple Mus caroli alpha 1-acid glycoprotein (AGP) genes. Differences in glucocorticoid stimulation and regulatory elements between the rat and mouse AGP genes.","2354997",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24693788","[Effect of transforming growth factor beta3, bone morphogenetic protein 2, and dexamethasone on chondrogenic differentiation of rabbit synovial mesenchymal stem cells].","24693788",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1995,"7534698","Effect of glucocorticoid on insulin-like growth factor (IGF) regulation of IGF-binding protein expression in fibroblasts.","7534698",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1988,"2965706","Expression and dexamethasone regulation of the human corticotropin-releasing hormone gene in a mouse anterior pituitary cell line.","2965706",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1987,"3469661","Hepatitis B surface antigen gene expression is regulated by sex steroids and glucocorticoids in transgenic mice.","3469661",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1994,"8052265","A thyroid hormone receptor-dependent glucocorticoid induction.","8052265",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1996,"8730005","Modulation of ICAM-1 expression in human alveolar macrophages in vitro.","8730005",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1997,"9356235","Effect of dexamethasone on NF-kB activation, tumor necrosis factor formation, and glucose dyshomeostasis in septic rats.","9356235",42]
["Dexamethasone Isonicotinate","Dexamethasone Isonicotinate","D003908","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16594601","Effect of beclomethasone dipropionate and dexamethasone isonicotinate on lung function, bronchoalveolar lavage fluid cytology, and transcription factor expression in airways of horses with recurrent airway obstruction.","16594601",42]
["Dextran Sulfate","Dextran Sulfate","D016264","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"27286916","Semi-bionic extraction of compound turmeric protects against dextran sulfate sodium-induced acute enteritis in rats.","27286916",42]
["Diazepam","Diazepam","D003975","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"14741402","Ethanol withdrawal-induced up-regulation of the alpha2 subunit of the GABAA receptor and its prevention by diazepam or gamma-hydroxybutyric acid.","14741402",42]
["dibenzoylpropane","dibenzoylpropane","C568970","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"21924245","Suppression of pro-inflammatory and proliferative pathways by diferuloylmethane (curcumin) and its analogues dibenzoylmethane, dibenzoylpropane, and dibenzylideneacetone: role of Michael acceptors and Michael donors.","21924245",42]
["dictyopyrone A","dictyopyrone A","C507376","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"16219041","Dictyopyrones, novel alpha-pyronoids isolated from Dictyostelium spp., promote stalk cell differentiation in Dictyostelium discoideum.","16219041",42]
["Dietary Fiber","Dietary Fiber","D004043","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27476413","Gut Microbial Metabolites Fuel Host Antibody Responses.","27476413",42]
["Diethylhexyl Phthalate","Diethylhexyl Phthalate","D004051","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21079920","Role of phospholipase D in regulation of testicular Leydig cell hyperplasia in Sprague-Dawley rats treated with di(2-ethylhexyl) phthalate.","21079920",42]
["Diethylhexyl Phthalate","Diethylhexyl Phthalate","D004051","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1993,"8352887","Activation of immediate-early gene expression by peroxisome proliferators in vitro.","8352887",42]
["Diethylstilbestrol","Diethylstilbestrol","D004054","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"22659056","Is the current product safety assessment paradigm protective for epigenetic mechanisms?","22659056",42]
["dihydroxy-vitamin D3","dihydroxy-vitamin D3","C118756","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19178594","1alpha,25-dihydroxyvitamin D3 inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection.","19178594",42]
["diisopropanolnitrosamine","diisopropanolnitrosamine","C012457","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"23832296","Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles.","23832296",42]
["Dimethyl Sulfoxide","Dimethyl Sulfoxide","D004121","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1980,"6935071","New gene expression in dimethylsulfoxide-treated Friend erythroleukemia cells.","6935071",42]
["Dinoprost","Dinoprost","D015237","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2004,"15388641","Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: a new mechanism linking HDL protein composition and antiatherogenic potential.","15388641",42]
["Dinoprost","Dinoprost","D015237","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"25102061","Profiling of luteal transcriptome during prostaglandin F2-alpha treatment in buffalo cows: analysis of signaling pathways associated with luteolysis.","25102061",42]
["Dinoprostone","Dinoprostone","D015232","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"12209884","Flavanones structure-related inhibition on TPA-induced tumor promotion through suppression of extracellular signal-regulated protein kinases: involvement of prostaglandin E2 in anti-promotive process.","12209884",42]
["Dinoprostone","Dinoprostone","D015232","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15723041","Resetting of peripheral circadian clock by prostaglandin E2.","15723041",42]
["Dinoprostone","Dinoprostone","D015232","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21183242","Dendritic cells matured by a prostaglandin E2-containing cocktail can produce high levels of IL-12p70 and are more mature and Th1-biased than dendritic cells treated with TNF-α or LPS.","21183242",42]
["Dinoprostone","Dinoprostone","D015232","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22969242","Prostaglandin E(2) and interleukin-1β reduce E-cadherin expression by enhancing snail expression in gastric cancer cells.","22969242",42]
["Dinoprostone","Dinoprostone","D015232","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24419976","Compensatory cellular reactions to nonsteroidal anti-inflammatory drugs on osteogenic differentiation in canine bone marrow-derived mesenchymal stem cells.","24419976",42]
["Dinoprostone","Dinoprostone","D015232","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"26875548","Macrophages programmed by apoptotic cells inhibit epithelial-mesenchymal transition in lung alveolar epithelial cells via PGE2, PGD2, and HGF.","26875548",42]
["dioleoyl phosphatidylethanolamine","dioleoyl phosphatidylethanolamine","C094877","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23092705","The role of the helper lipid dioleoylphosphatidylethanolamine (DOPE) for DNA transfection cooperating with a cationic lipid bearing ethylenediamine.","23092705",42]
["diphenyldiselenide","diphenyldiselenide","C061132","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"27487292","Diphenyl Diselenide Reduces Oxidative Stress and Toxicity Caused by HSV-2 Infection in Mice.","27487292",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1999,"10462695","MK-801-induced expression of Fos protein family members in the rat retrosplenial granular cortex.","10462695",42]
["Domperidone","Domperidone","D004294","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"26965953","Effects of the fish spawning inducer ovaprim on vasotocin receptor gene expression in brain and ovary of the catfish Heteropneustes fossilis with a note on differential transcript expression in ovarian follicles.","26965953",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2000,"10882795","Effects of MK-801 on D1 dopamine receptor-mediated immediate early gene expression in the dopamine-depleted striatum.","10882795",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11703467","Unilateral striatal dopamine depletion: time-dependent effects on cortical function and behavioural correlates.","11703467",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2003,"14612146","Regulation of dopamine transporter function and plasma membrane expression by dopamine, amphetamine, and cocaine.","14612146",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1991,"1685231","Dopaminergic D1 and D2 receptor antagonists decrease prosomatostatin mRNA expression in rat striatum.","1685231",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17250655","Substrates and inhibitors display different sensitivity to expression level of the dopamine transporter in heterologously expressing cells.","17250655",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2008,"18185106","D1 receptor regulation of preprotachykinin-A gene by extracellular signal-regulated kinase pathway in striatal cultures.","18185106",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2009,"19091889","Striatal dopamine transporter availability associated with polymorphisms in the dopamine transporter gene SLC6A3.","19091889",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21289604","Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area.","21289604",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"22314364","Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells.","22314364",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23314440","Multigenerational effects of adolescent morphine exposure on dopamine D2 receptor function.","23314440",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24673634","The dopamine transporter expression level differentially affects responses to cocaine and amphetamine.","24673634",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1994,"7511845","Neostriatal dopamine receptors.","7511845",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1996,"8783238","Changes in striatal immediate early gene expression following neonatal dopaminergic lesion and effects of intrastriatal dopaminergic transplants.","8783238",42]
["Doxazosin","Doxazosin","D017292","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15573147","Doxazosin-induced up-regulation of alpha 1A-adrenoceptor mRNA in the rat lower urinary tract.","15573147",42]
["Doxorubicin","Doxorubicin","D004317","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17432542","Differential expression of HSP70 and ultrastructure of heart and liver tissues of rats treated with adriamycin: protective role of L-carnitine.","17432542",42]
["Doxorubicin","Doxorubicin","D004317","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"26956167","A Targeted DNAzyme-Nanocomposite Probe Equipped with Built-in Zn(2+) Arsenal for Combined Treatment of Gene Regulation and Drug Delivery.","26956167",42]
["Doxycycline","Doxycycline","D004318","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11331286","Use of the tetracycline-controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice.","11331286",42]
["Doxycycline","Doxycycline","D004318","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18687064","Attenuation of leakiness in doxycycline-inducible expression via incorporation of 3' AU-rich mRNA destabilizing elements.","18687064",42]
["Dronabinol","Dronabinol","D013759","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15454482","Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway.","15454482",42]
["Duffy Blood-Group System","Duffy Blood-Group System","D004375","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20932074","The Duffy blood group system: a review.","20932074",42]
["Durapatite","Durapatite","D017886","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"19857609","Biological responses of human osteoblasts and osteoclasts to flame-sprayed coatings of hydroxyapatite and fluorapatite blends.","19857609",42]
["Durapatite","Durapatite","D017886","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"28026000","Low-magnitude, high-frequency vibration promotes the adhesion and the osteogenic differentiation of bone marrow-derived mesenchymal stem cells cultured on a hydroxyapatite-coated surface: The direct role of Wnt/β-catenin signaling pathway activation.","28026000",42]
["Edetic Acid","Edetic Acid","D004492","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26599228","Towards Clinical Applications of Blood-Borne miRNA Signatures: The Influence of the Anticoagulant EDTA on miRNA Abundance.","26599228",42]
["Eicosapentaenoic Acid","Eicosapentaenoic Acid","D015118","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2006,"16616699","Eicosapentaenoic acid and docosahexaenoic acid modulate mitogen-activated protein kinase activity in endothelium.","16616699",42]
["Eicosapentaenoic Acid","Eicosapentaenoic Acid","D015118","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24798452","The ω-3 polyunsaturated fatty acid, eicosapentaenoic acid, attenuates abdominal aortic aneurysm development via suppression of tissue remodeling.","24798452",42]
["Emodin","Emodin","D004642","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2009,"18785977","Hypoglycaemic and hypolipidaemic effects of emodin and its effect on L-type calcium channels in dyslipidaemic-diabetic rats.","18785977",42]
["endothelium-dependent hyperpolarization factor","endothelium-dependent hyperpolarization factor","C067410","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2006,"16624628","Specific impairment of endothelium-derived hyperpolarizing factor-type relaxation in mesenteric arteries from streptozotocin-induced diabetic mice.","16624628",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C27459,B27459)","v":"enterotoxin A, Staphylococcal"},"enterotoxin A, Staphylococcal","C026066","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J27459,K27459)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,1,2003,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q27459,Q27459)","v":"12890448"},"Plasticity of IL-2 and IL-2 receptor chains in rat lymphoid tissues in situ after stimulation with staphylococcal enterotoxin A.","12890448",42]
["enterotoxin B, staphylococcal","enterotoxin B, staphylococcal","C031818","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1996,"8892628","Cross-linking of MHC class II molecules by staphylococcal enterotoxin A is essential for antigen-presenting cell and T cell activation.","8892628",42]
["epigallocatechin gallate","epigallocatechin gallate","C045651","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20488180","Epigallocatechin-3-gallate protects motor neurons and regulates glutamate level.","20488180",42]
["epigallocatechin gallate","epigallocatechin gallate","C045651","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24392721","Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas(lpr) mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2.","24392721",42]
["epiglucan","epiglucan","C033671","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"27742589","β-1,3/1,6-Glucan-supplemented diets antagonize immune inhibitory effects of hypoxia and enhance the immune response to a model vaccine.","27742589",42]
["Epinephrine","Epinephrine","D004837","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1994,"7907998","Regulation of human insulin gene transcription by glucose, epinephrine, and somatostatin.","7907998",42]
["Epstein-Barr virus early antigen","Epstein-Barr virus early antigen","C033305","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1984,"6087334","Expression of a nuclear and a cytoplasmic Epstein-Barr virus early antigen after DNA transfer: cooperation of two distant parts of the genome for expression of the cytoplasmic antigen.","6087334",42]
["Erlotinib Hydrochloride","Erlotinib Hydrochloride","D000069347","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"24976727","Distinct antifibrogenic effects of erlotinib, sunitinib and sorafenib on rat pancreatic stellate cells.","24976727",42]
["er'zhi tiangui","er'zhi tiangui","C579122","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"23086489","Effects of Er'zhi Tiangui Granule () on sequential expressions of integrin β 3 and its ligand osteopontin in mouse endometrium during controlled ovarian hyperstimulation.","23086489",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2000,"10973806","Geranylgeranylacetone enhances expression of thioredoxin and suppresses ethanol-induced cytotoxicity in cultured hepatocytes.","10973806",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16554353","Chronic ethanol feeding increases activation of NADPH oxidase by lipopolysaccharide in rat Kupffer cells: role of increased reactive oxygen in LPS-stimulated ERK1/2 activation and TNF-alpha production.","16554353",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"17029600","Regulation of alpha-synuclein expression in alcohol-preferring and -non preferring rats.","17029600",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18588946","Novel role of adrenergic neurons in the brain stem in mediating the hypothalamic-pituitary axis hyperactivity caused by prenatal alcohol exposure.","18588946",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20173759","Long-term ethanol exposure inhibits glucose transporter 4 expression via an AMPK-dependent pathway in adipocytes.","20173759",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23605000","Pulmonary cytokine composition differs in the setting of alcohol use disorders and cigarette smoking.","23605000",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24730561","Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse.","24730561",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25821971","Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions.","25821971",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1997,"9161404","Transcriptional regulation of tracheo-bronchial mucin (TBM) gene by ethanol.","9161404",42]
["ethyl glucoside","ethyl glucoside","C108400","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28715254","Effects of ethyl-α-d-glucoside on human dermal fibroblasts.","28715254",42]
["ethylene","ethylene","C036216","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1986,"2428042","Ethylene-regulated gene expression: molecular cloning of the genes encoding an endochitinase from Phaseolus vulgaris.","2428042",42]
["etiracetam","etiracetam","C026098","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"14725628","The antiepileptic drug levetiracetam selectively modifies kindling-induced alterations in gene expression in the temporal lobe of rats.","14725628",42]
["euxanthone","euxanthone","C404221","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"11927399","Effects of dibutyryl cAMP on stanniocalcin and stanniocalcin-related protein mRNA expression in neuroblastoma cells.","11927399",42]
["F62 lipooligosaccharide","F62 lipooligosaccharide","C071915","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1991,"1720505","Epitope expression and partial structural characterization of F62 lipooligosaccharide (LOS) of Neisseria gonorrhoeae: IgM monoclonal antibodies (3F11 and 1-1-M) recognize non-reducing termini of the LOS components.","1720505",42]
["fasudil","fasudil","C049347","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24405591","[Inhibition of Fasudil on lipopolysaccharide-induced TNF-α and IL-1β expressions through TLR4 pathway in murine BV-2 cells in vitro].","24405591",42]
["Fenofibrate","Fenofibrate","D011345","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1997,"9108325","Fenofibrate differently alters expression of genes encoding ATP-binding transporter proteins of the peroxisomal membrane.","9108325",42]
["fenvalerate","fenvalerate","C017690","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15178118","Molecular and cellular biomarker responses to pesticide exposure in juvenile chinook salmon (Oncorhynchus tshawytscha).","15178118",42]
["ferric oxide, saccharated","ferric oxide, saccharated","C008169","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28586635","Tin protoporphyrin activates the oxidant-dependent NRF2-cytoprotective pathway and mitigates acute kidney injury.","28586635",42]
["ferumoxides","ferumoxides","C065507","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19489018","Magnetic resonance imaging and biological properties of pancreatic islets labeled with iron oxide nanoparticles.","19489018",42]
["Fingolimod Hydrochloride","Fingolimod Hydrochloride","D000068876","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20501676","Diabetes prevention by immunomodulatory FTY720 treatment in the LEW.1AR1-iddm rat despite immune cell activation.","20501676",42]
["Flumazenil","Flumazenil","D005442","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17403139","Flumazenil selectively prevents the increase in alpha(4)-subunit gene expression and an associated change in GABA(A) receptor function induced by ethanol withdrawal.","17403139",42]
["Fluorescein-5-isothiocyanate","Fluorescein-5-isothiocyanate","D016650","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1990,"2126468","Influence of imprinting with A and B chains of insulin on binding and functional changes in tetrahymena.","2126468",42]
["Fluoxetine","Fluoxetine","D005473","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21301813","Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes.","21301813",42]
["Fluticasone","Fluticasone","D000068298","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24395918","Chronic exposure to glucocorticoids shapes gene expression and modulates innate and adaptive activation pathways in macrophages with distinct changes in leukocyte attraction.","24395918",42]
["Folic Acid","Folic Acid","D005492","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"17681772","Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines.","17681772",42]
["Folic Acid","Folic Acid","D005492","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23859838","Folic acid attenuates hyperhomocysteinemia-induced glomerular damage in rats.","23859838",42]
["Folic Acid","Folic Acid","D005492","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1997,"9256160","Cross-resistance to antifolates in multidrug resistant cell lines with P-glycoprotein or multidrug resistance protein expression.","9256160",42]
["Freund's Adjuvant","Freund's Adjuvant","D005620","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28337634","Topical dura mater application of CFA induces enhanced expression of c-fos and glutamate in rat trigeminal nucleus caudalis: attenuated by KYNA derivate (SZR72).","28337634",42]
["Fructose","Fructose","D005632","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20536716","Dietary fructose exacerbates hepatocellular injury when incorporated into a methionine-choline-deficient diet.","20536716",42]
["Fructose","Fructose","D005632","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26458107","A Grape Seed Procyanidin Extract Ameliorates Fructose-Induced Hypertriglyceridemia in Rats via Enhanced Fecal Bile Acid and Cholesterol Excretion and Inhibition of Hepatic Lipogenesis.","26458107",42]
["fructose-1,6-diphosphate","fructose-1,6-diphosphate","C029063","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28242545","Fructose-1,6-bisphosphate decreases IL-8 levels and increases the activity of pro-apoptotic proteins in HepG2 cells.","28242545",42]
["furan","furan","C039281","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26361796","Mining the Archives: A Cross-Platform Analysis of Gene Expression Profiles in Archival Formalin-Fixed Paraffin-Embedded Tissues.","26361796",42]
["Gabexate","Gabexate","D016670","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1999,"10669038","Different effects of trypsin inhibitors on intestinal gene expression of secretin and on pancreatic bicarbonate secretion in CCK-A-receptor-deficient rats.","10669038",42]
["Galactosamine","Galactosamine","D005688","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28887131","Prostacyclin mimetics afford protection against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.","28887131",42]
["Gallic Acid","Gallic Acid","D005707","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27703224","Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity.","27703224",42]
["Ganciclovir","Ganciclovir","D015774","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"12509912","[Bystander effect mediated by herpes simplex virus-thymidine kinase/ganciclovir approach on prostatic cancer cells and its regulation].","12509912",42]
["gardiquimod","gardiquimod","C546771","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"24057248","Gardiquimod inhibits the expression of calcium-induced differentiation markers in HaCaT cells.","24057248",42]
["Gemfibrozil","Gemfibrozil","D015248","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"25750174","Activation of peroxisome proliferator-activated receptor α induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders.","25750174",42]
["Genistein","Genistein","D019833","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"25620059","Genistein modulates the expression of NF-κB and MAPK (p-38 and ERK1/2), thereby attenuating d-Galactosamine induced fulminant hepatic failure in Wistar rats.","25620059",42]
["Geraniin","Geraniin","C024603","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27290719","Geraniin Inhibits LPS-Induced THP-1 Macrophages Switching to M1 Phenotype via SOCS1/NF-κB Pathway.","27290719",42]
["Ginkgo biloba extract","Ginkgo biloba extract","C063170","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"19064852","Effect of topical Ginkgo biloba extract on steroid-induced changes in the trabecular meshwork and intraocular pressure.","19064852",42]
["ginsenoside Rb1","ginsenoside Rb1","C442759","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22240916","Ginsenoside-Rb1 and tetramethylpyrazine phosphate act synergistically to prevent dilated cardiomyopathy in cTnTR141W transgenic mice.","22240916",42]
["glabridin","glabridin","C107601","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22038020","The inhibitory effect and the molecular mechanism of glabridin on RANKL-induced             osteoclastogenesis in RAW264.7 cells.","22038020",42]
["Glucosamine","Glucosamine","D005944","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2005,"16142878","N-acylation of glucosamine modulates chondrocyte growth, proteoglycan synthesis, and gene expression.","16142878",42]
["glucosamine 6-phosphate","glucosamine 6-phosphate","C001293","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"19427183","Phosphorylated glucosamine inhibits adipogenesis in 3T3-L1 adipocytes.","19427183",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2000,"10764781","Transgenic overexpression of hexokinase II in skeletal muscle does not increase glucose disposal in wild-type or Glut1-overexpressing mice.","10764781",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2002,"12660874","Direct peripheral effects of ghrelin include suppression of adiponectin expression.","12660874",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2004,"15081316","Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure.","15081316",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2005,"15855334","Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study.","15855334",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2006,"17046547","High-fat/low-carbohydrate diets regulate glucose metabolism via a long-term transcriptional loop.","17046547",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"17509747","Glucose enhances protein tyrosine phosphatase 1B gene transcription in hepatocytes.","17509747",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17960513","The combination of high glucose and advanced glycation end-products (AGEs) inhibits the mineralization of osteoblastic MC3T3-E1 cells through glucose-induced increase in the receptor for AGEs.","17960513",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20002497","Multiple roles of PPARalpha in brown adipose tissue under constitutive and cold conditions.","20002497",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20081857","Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.","20081857",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"21814490","Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation.","21814490",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"21316350","Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake.","21316350",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"21988232","miR-486-5p induces replicative senescence of human adipose tissue-derived mesenchymal stem cells and its expression is controlled by high glucose.","21988232",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"22930659","Proteomic profiling of high glucose primed monocytes identifies cyclophilin A as a potential secretory marker of inflammation in type 2 diabetes.","22930659",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23431017","TCF7L2 and glucose metabolism: time to look beyond the pancreas.","23431017",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23936124","Involvement of the clock gene Rev-erb alpha in the regulation of glucagon secretion in pancreatic alpha-cells.","23936124",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"25047839","Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.","25047839",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"25594873","Non-classical gluconeogenesis-dependent glucose metabolism in Rhipicephalus microplus embryonic cell line BME26.","25594873",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26021979","High glucose and/or high insulin affects HIF-1 signaling by regulating AIP1 in human umbilical vein endothelial cells.","26021979",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27997591","The Role of Glucose Metabolism on Porcine Oocyte Cytoplasmic Maturation and Its Possible Mechanisms.","27997591",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27731349","TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells.","27731349",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1987,"2824512","Differential effects of glucose and fructose on liver L-type pyruvate kinase gene expression in vivo.","2824512",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28661453","LXRα Regulates Hepatic ChREBPα Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice.","28661453",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2018,"29656931","Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles.","29656931",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1996,"8866414","Captopril reverses high-glucose-induced growth effects on LLC-PK1 cells partly by decreasing transforming growth factor-beta receptor protein expressions.","8866414",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9612275","Selecting agent hygromycin B alters expression of glucose-regulated genes in transfected Caco-2 cells.","9612275",42]
["Glutaral","Glutaral","D005976","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"23109832","Biocompatibility of genipin and glutaraldehyde cross-linked chitosan materials in the anterior chamber of the eye.","23109832",42]
["Glycerol","Glycerol","D005990","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28961924","Glycerol and testicular activity: the good, the bad and the ugly.","28961924",42]
["glycoinositolphospholipid, Trypanosoma","glycoinositolphospholipid, Trypanosoma","C115336","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1999,"10463955","Costimulatory action of glycoinositolphospholipids from Trypanosoma cruzi: increased interleukin 2 secretion and induction of nuclear translocation of the nuclear factor of activated T cells 1.","10463955",42]
["Glycyrrhizic Acid","Glycyrrhizic Acid","D019695","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"25152329","Role of Nrf2 activation and NF-κB inhibition in valproic acid induced hepatotoxicity and in diammonium glycyrrhizinate induced protection in mice.","25152329",42]
["Grape Seed Extract","Grape Seed Extract","D056604","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"21829010","Catechin-rich grape seed extract supplementation attenuates diet-induced obesity in C57BL/6J mice.","21829010",42]
["Guanine","Guanine","D006147","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2006,"16904066","An essential GT motif in the lamin A promoter mediates activation by CREB-binding protein.","16904066",42]
["GW 3965","GW 3965","C473027","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16525352","Activation of the liver X receptor protects against hepatic injury in endotoxemia by suppressing Kupffer cell activation.","16525352",42]
["H-2K(K) antigen","H-2K(K) antigen","C024755","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1982,"7135165","Dominant allele-specific regulation of expression of H-2Kk gene products revealed by somatic cell hybridization.","7135165",42]
["Haloperidol","Haloperidol","D006220","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"12243769","Induction of differential patterns of local cerebral glucose metabolism and immediate-early genes by acute clozapine and haloperidol.","12243769",42]
["HC-067047","HC-067047","C573308","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"24965792","Intravesical TRPV4 blockade reduces repeated variate stress-induced bladder dysfunction by increasing bladder capacity and decreasing voiding frequency in male rats.","24965792",42]
["Heme","Heme","D006418","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"18037887","Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta.","18037887",42]
["Heme","Heme","D006418","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"26943999","Characterization and expression analysis of gene encoding heme peroxidase HPX15 in major Indian malaria vector Anopheles stephensi (Diptera: Culicidae).","26943999",42]
["Heme","Heme","D006418","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1983,"6301690","Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site.","6301690",42]
["Heparin","Heparin","D006493","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17488504","Alterations in cytoskeletal and immune function-related proteome profiles in whole rat lung following intratracheal instillation of heparin.","17488504",42]
["Heparin","Heparin","D006493","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28380442","Monocytes, endoplasmic reticulum stress and metabolomics in dogs with multiple organ dysfunction syndrome treated by continuous venovenous hemodiafiltration.","28380442",42]
["Heparitin Sulfate","Heparitin Sulfate","D006497","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16514633","The use of heparan sulfate to augment fracture repair in a rat fracture model.","16514633",42]
["Heroin","Heroin","D003932","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23113797","Unique gene alterations are induced in FACS-purified Fos-positive neurons activated during cue-induced relapse to heroin seeking.","23113797",42]
["hexabromocyclododecane","hexabromocyclododecane","C089796","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15585367","Modulation at a cellular level of the thyroid hormone receptor-mediated gene expression by 1,2,5,6,9,10-hexabromocyclododecane (HBCD), 4,4'-diiodobiphenyl (DIB), and nitrofen (NIP).","15585367",42]
["hexamethylene bisacetamide","hexamethylene bisacetamide","C014026","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1987,"3326466","Induction of transformed cells to terminal differentiation.","3326466",42]
["Histamine","Histamine","D006632","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15514212","Granulocyte macrophage-colony stimulating factor increases the expression of histamine and histamine receptors in monocytes/macrophages in relation to arteriosclerosis.","15514212",42]
["Histamine","Histamine","D006632","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"22618577","Expression of Toll-like receptors in enterocromaffin-like cells and their function in histamine release.","22618577",42]
["Histocompatibility Antigen H-2D","Histocompatibility Antigen H-2D","D064532","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1993,"8429526","Unusual expression pattern of the MHC class I Q5k gene in the AKR mouse: possible role in embryo development.","8429526",42]
["huperzine A","huperzine A","C050426","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21289607","Huperzine A activates Wnt/β-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse model.","21289607",42]
["Hyaluronic Acid","Hyaluronic Acid","D006820","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16733556","Elevated level of ambient glucose stimulates the synthesis of high-molecular-weight hyaluronic acid by human mesangial cells. The involvement of transforming growth factor beta1 and its activation by thrombospondin-1.","16733556",42]
["Hyaluronic Acid","Hyaluronic Acid","D006820","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23530033","The hyaluronan receptor for endocytosis (HARE) activates NF-κB-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans.","23530033",42]
["Hyaluronic Acid","Hyaluronic Acid","D006820","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26379083","Niche Mimicking for Selection and Enrichment of Liver Cancer Stem Cells by Hyaluronic Acid-Based Multilayer Films.","26379083",42]
["Hyaluronic Acid","Hyaluronic Acid","D006820","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28474484","Hyaluronan keeps mesenchymal stem cells quiescent and maintains the differentiation potential over time.","28474484",42]
["Hydrogel, Polyethylene Glycol Dimethacrylate","Hydrogel, Polyethylene Glycol Dimethacrylate","D020136","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"21916017","Hyperosmolarity and hypoxia induce chondrogenesis of adipose-derived stem cells in a collagen type 2 hydrogel.","21916017",42]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2006,"16548067","A parallel proteomic and metabolomic analysis of the hydrogen peroxide- and Sty1p-dependent stress response in Schizosaccharomyces pombe.","16548067",42]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18515041","Antimutagenic, antigenotoxic and antioxidant activities of Acacia salicina extracts (ASE) and modulation of cell gene expression by H2O2 and ASE treatment.","18515041",42]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"21674797","The peroxide stress response of Bacillus licheniformis.","21674797",42]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"24594261","Analysis of the expression and antioxidant activity of 2-Cys peroxiredoxin protein in Fasciola gigantica.","24594261",42]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28937872","Protective Effect of Combined Caffeic Acid Phenethyl Ester and Bevacizumab Against Hydrogen Peroxide-Induced Oxidative Stress in Human RPE Cells.","28937872",42]
["Hydrogen Sulfide","Hydrogen Sulfide","D006862","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22209714","Hydrogen sulfide-releasing aspirin modulates xenobiotic metabolizing enzymes in vitro and in vivo.","22209714",42]
["Hydrogen Sulfide","Hydrogen Sulfide","D006862","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"25747480","Anti-inflammatory and cytoprotective properties of hydrogen sulfide.","25747480",42]
["Hydroxyl Radical","Hydroxyl Radical","D017665","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20164374","Hyperglycemia induces apoptosis in rat liver through the increase of hydroxyl radical: new insights into the insulin effect.","20164374",42]
["Hydroxyurea","Hydroxyurea","D006918","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2006,"16530854","Pathophysiologically based drug treatment of sickle cell disease.","16530854",42]
["Hydroxyurea","Hydroxyurea","D006918","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1987,"3681903","The effect of hydroxyurea on the expression of the common fragile site at 3p14.","3681903",42]
["Hymecromone","Hymecromone","D006923","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23594483","4-Methylumbelliferone inhibits the phosphorylation of hyaluronan synthase 2 induced by 12-O-tetradecanoyl-phorbol-13-acetate.","23594483",42]
["icariin","icariin","C056599","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25389062","Icariin inhibits foam cell formation by down-regulating the expression of CD36 and up-regulating the expression of SR-BI.","25389062",42]
["idebenone","idebenone","C036619","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"26625322","Efficient attenuation of Friedreich's ataxia (FRDA) cardiomyopathy by modulation of iron homeostasis-human induced pluripotent stem cell (hiPSC) as a drug screening platform for FRDA.","26625322",42]
["imidapril","imidapril","C065166","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"11893585","Long-term inhibition of nitric oxide synthesis increases arterial thrombogenecity in rat carotid artery.","11893585",42]
["imiquimod","imiquimod","C056493","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"27568525","Spread of Psoriasiform Inflammation to Remote Tissues Is Restricted by the Atypical Chemokine Receptor ACKR2.","27568525",42]
["Indocyanine Green","Indocyanine Green","D007208","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15141011","Photodynamic therapy with indocyanine green complements and enhances low-dose cisplatin cytotoxicity in MCF-7 breast cancer cells.","15141011",42]
["Indomethacin","Indomethacin","D007213","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1994,"7945342","IL-1 beta regulates the expression of the Gi2 alpha gene via lipid mediators in guinea pig tracheal muscle.","7945342",42]
["Inositol","Inositol","D007294","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24291779","Inositol-C2-PAF down-regulates components of the antigen presentation machinery in a 2D-model of epidermal inflammation.","24291779",42]
["inositol-1,3,4,5-tetrakisphosphate","inositol-1,3,4,5-tetrakisphosphate","C081655","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2002,"11869802","Cellular expression and subcellular localization of the human Ins(1,3,4,5)P(4)-binding protein, p42(IP4), in human brain and in neuronal cells.","11869802",42]
["irofulven","irofulven","C102714","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15640616","Irofulven: resurgence for alkylating therapy in cancer?","15640616",42]
["isocampneoside II","isocampneoside II","C587325","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23770344","Antioxidant properties and neuroprotective effects of isocampneoside II on hydrogen peroxide-induced oxidative injury in PC12 cells.","23770344",42]
["Isoflurane","Isoflurane","D007530","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25953616","The Pore Loop Domain of TRPV1 Is Required for Its Activation by the Volatile Anesthetics Chloroform and Isoflurane.","25953616",42]
["Isoproterenol","Isoproterenol","D007545","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1991,"1995617","Secretagogue-coupled changes in the expression of glutamine/glutamic acid-rich proteins (GRPs). Isoproterenol induces changes in GRP transcript expression and changes in isoforms secreted.","1995617",42]
["Isoproterenol","Isoproterenol","D007545","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1989,"2547776","Agonist regulation of beta-adrenergic receptor mRNA. Analysis in S49 mouse lymphoma mutants.","2547776",42]
["Isotretinoin","Isotretinoin","D015474","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"18987667","Isotretinoin temporally regulates distinct sets of genes in patient skin.","18987667",42]
["Ivermectin","Ivermectin","D007559","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23648830","Abamectin resistance in Drosophila is related to increased expression of P-glycoprotein via the dEGFR and dAkt pathways.","23648830",42]
["kaempferol","kaempferol","C006552","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"23398429","Kaempferol improves carcase characteristics in broiler chickens by regulating ANGPTL3 gene expression.","23398429",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1999,"10443546","Effects of pilocarpine- and kainate-induced seizures on thyrotropin-releasing hormone biosynthesis and receptors in the rat brain.","10443546",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18094625","An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid.","18094625",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1993,"8417141","Kainate-induced changes in opioid peptide genes and AP-1 protein expression in the rat hippocampus.","8417141",42]
["Ketamine","Ketamine","D007649","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22627142","Subchronic ketamine treatment leads to permanent changes in EEG, cognition and the astrocytic glutamate transporter EAAT2 in mice.","22627142",42]
["Ketoprofen","Ketoprofen","D007660","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22721833","Does ketoprofen or diclofenac pose the lowest risk to fish?","22721833",42]
["KNK 437","KNK 437","C410027","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"17055158","The heat shock protein inhibitor KNK437 induces neurite outgrowth in PC12 cells.","17055158",42]
["Lactic Acid","Lactic Acid","D019344","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22243931","Fabrication of a Layered Microstructured Polymeric Microspheres as a Cell Carrier for Nucleus Pulposus Regeneration.","22243931",42]
["Lactic Acid","Lactic Acid","D019344","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27326916","Investigation of angiogenesis in bioactive 3-dimensional poly(d,l-lactide-co-glycolide)/nano-hydroxyapatite scaffolds by in vivo multiphoton microscopy in murine calvarial critical bone defect.","27326916",42]
["Lactose","Lactose","D007785","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28442546","Modeled structural basis for the recognition of α2-3-sialyllactose by soluble Klotho.","28442546",42]
["Lasalocid","Lasalocid","D007832","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1992,"1438308","Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids.","1438308",42]
["Leukotriene B4","Leukotriene B4","D007975","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20304963","The LTB4-BLT1 axis mediates neutrophil infiltration and secondary injury in experimental spinal cord injury.","20304963",42]
["Leukotriene D4","Leukotriene D4","D017998","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2005,"16042577","Pro-inflammatory mediator leukotriene D4 induces transcriptional activity of potentially oncogenic genes.","16042577",42]
["levormeloxifene","levormeloxifene","C108255","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2008,"18804812","Effects of estrogen, raloxifene and levormeloxifene on alpha1A-adrenergic receptor expression.","18804812",42]
["LG 100754","LG 100754","C101596","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1996,"8837780","Activation of specific RXR heterodimers by an antagonist of RXR homodimers.","8837780",42]
["Linoleic Acid","Linoleic Acid","D019787","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28643621","Linoleic acid, α-linolenic acid and enterolactone affect lipid oxidation and expression of lipid metabolism and antioxidant-related genes in hepatic tissue of dairy cows.","28643621",42]
["Lipid A","Lipid A","D008050","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19675119","Differential modulation of human {beta}-defensins expression in human gingival epithelia by Porphyromonas gingivalis lipopolysaccharide with tetra- and penta-acylated lipid A structures.","19675119",42]
["lipoarabinomannan","lipoarabinomannan","C050016","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1994,"8132324","Induction of early-response genes KC and JE by mycobacterial lipoarabinomannans: regulation of KC expression in murine macrophages by Lsh/Ity/Bcg (candidate Nramp).","8132324",42]
["lipopolysaccharide, E coli O55-B5","lipopolysaccharide, E coli O55-B5","C482199","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23499680","(E)-1-(4-ethoxyphenyl)-3-(4-nitrophenyl)-prop-2-en-1-one suppresses LPS-induced inflammatory response through inhibition of NF-κB signaling pathway.","23499680",42]
["lipoxin A4","lipoxin A4","C040527","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"24249731","Modulation of voltage-dependent and inward rectifier potassium channels by 15-epi-lipoxin-A4 in activated murine macrophages: implications in innate immunity.","24249731",42]
["Lithium Chloride","Lithium Chloride","D018021","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"19840776","Lithium modulates tryptophan hydroxylase 2 gene expression and serotonin release in primary cultures of serotonergic raphe neurons.","19840776",42]
["lithospermic acid","lithospermic acid","C046833","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2009,"19217780","Lithospermic acid derivatives from Lithospermum erythrorhizon increased expression of serine palmitoyltransferase in human HaCaT cells.","19217780",42]
["Losartan","Losartan","D019808","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"26648157","Prehypertensive treatment with losartan, however not amlodipine, leads to long-term effects on blood pressure and reduces the risk of stroke in spontaneously hypertensive stroke-prone rats.","26648157",42]
["Lovastatin","Lovastatin","D008148","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24718106","Efficacy of lovastatin on learning and memory deficits caused by chronic intermittent hypoxia-hypercapnia: through regulation of NR2B-containing NMDA receptor-ERK pathway.","24718106",42]
["Luteolin","Luteolin","D047311","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"16116295","Luteolin inhibits endothelin-1 secretion in cultured endothelial cells.","16116295",42]
["Luteolin","Luteolin","D047311","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27016074","Luteolin inhibits viral-induced inflammatory response in RAW264.7 cells via suppression of STAT1/3 dependent NF-κB and activation of HO-1.","27016074",42]
["lysophosphatidic acid","lysophosphatidic acid","C032881","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16504475","Vascular smooth muscle migration and proliferation in response to lysophosphatidic acid (LPA) is mediated by LPA receptors coupling to Gq.","16504475",42]
["lysophosphatidic acid","lysophosphatidic acid","C032881","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26482178","Lysophosphatidic acid modulates prostaglandin signalling in bovine steroidogenic luteal cells.","26482178",42]
["madecassoside","madecassoside","C093443","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"24352025","Madecassoside inhibits melanin synthesis by blocking ultraviolet-induced inflammation.","24352025",42]
["Malondialdehyde","Malondialdehyde","D008315","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15249212","Physical conditioning modulates rat cardiac vascular endothelial growth factor gene expression in nitric oxide-deficient hypertension.","15249212",42]
["Mannose","Mannose","D008358","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1988,"2450948","A human mannose-binding protein is an acute-phase reactant that shares sequence homology with other vertebrate lectins.","2450948",42]
["Materia Medica","Materia Medica","D008419","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"25090712","[Effect of retinociacdi combined extracts from testudinis carapacis et plastri on proliferating in MSCs and its mechanism].","25090712",42]
["Medroxyprogesterone Acetate","Medroxyprogesterone Acetate","D017258","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2000,"10650945","Transit of normal rat uterine stromal cells through G1 phase of the cell cycle requires progesterone-growth factor interactions.","10650945",42]
["Menhaden oil","Menhaden oil","C033266","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1993,"8378318","Polyunsaturated fatty acids inhibit S14 gene transcription in rat liver and cultured hepatocytes.","8378318",42]
["Mercuric Chloride","Mercuric Chloride","D008627","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1995,"7867088","Mercuric chloride-induced programmed cell death of a murine T cell hybridoma. I. Effect of the proto-oncogene Bcl-2.","7867088",42]
["Metformin","Metformin","D008687","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2009,"19470778","Regulation of visceral adipose tissue-derived serine protease inhibitor by nutritional status, metformin, gender and pituitary factors in rat white adipose tissue.","19470778",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C36419,B36419)","v":"Metformin"},"Metformin","D008687","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J36419,K36419)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,2,2014,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q36419,Q36419)","v":"24762064"},"Beneficial effects of pioglitazone and metformin in murine model of polycystic ovaries via improvement of chemerin gene up-regulation.","24762064",42]
["Metformin","Metformin","D008687","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28132912","Involvement of arterial baroreflex and nicotinic acetylcholine receptor α7 subunit pathway in the protection of metformin against stroke in stroke-prone spontaneously hypertensive rats.","28132912",42]
["Methamphetamine","Methamphetamine","D008694","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2009,"19689456","Genetically correlated effects of selective breeding for high and low methamphetamine consumption.","19689456",42]
["Methamphetamine","Methamphetamine","D008694","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24438490","Dual regulation of clock gene Per2 expression in discrete brain areas by the circadian pacemaker and methamphetamine-induced oscillator in rats.","24438490",42]
["methanandamide","methanandamide","C088155","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22792180","Opposite effects of methanandamide on lipopolysaccharide-induced prostaglandin E2 and F2α synthesis in uterine explants from pregnant mice.","22792180",42]
["Methotrexate","Methotrexate","D008727","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28468172","Methotrexate Induces Apoptosis in Organ-Cultured Nasal Polyps Via the Fas Pathway.","28468172",42]
["Methoxyhydroxyphenylglycol","Methoxyhydroxyphenylglycol","D008734","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15574735","A novel Ca2+-independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons.","15574735",42]
["methyl jasmonate","methyl jasmonate","C072239","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"26507893","Mitogen-activated protein kinase 6 mediates nuclear translocation of ORE3 to promote ORE9 gene expression in methyl jasmonate-induced leaf senescence.","26507893",42]
["methyl-beta-cyclodextrin","methyl-beta-cyclodextrin","C108732","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23866961","Methyl-β-cyclodextrin alters adipokine gene expression and glucose metabolism in swine adipose tissue.","23866961",42]
["Methylnitrosourea","Methylnitrosourea","D008770","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20424134","Methylselenocysteine resets the rhythmic expression of circadian and growth-regulatory genes disrupted by nitrosomethylurea in vivo.","20424134",42]
["Methylphenidate","Methylphenidate","D008774","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28633952","Chronic methylphenidate regulates genes and proteins mediating neuroplasticity in the juvenile rat brain.","28633952",42]
["Methyltestosterone","Methyltestosterone","D008777","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"17707136","Effects of 17alpha-methyltestosterone exposure on steroidogenesis and cyclin-B mRNA expression in previtellogenic oocytes of Atlantic cod (Gadus morhua).","17707136",42]
["mezerein","mezerein","C011309","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1985,"3933985","Role of protein synthesis in induction of interferon-gamma by mitogens in human lymphocytes.","3933985",42]
["Mifepristone","Mifepristone","D015735","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"17090971","Dopaminergic mechanisms involved in prolactin release after mifepristone and naloxone treatment during late pregnancy in the rat.","17090971",42]
["Mifepristone","Mifepristone","D015735","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1997,"9171233","The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT.","9171233",42]
["Minocycline","Minocycline","D008911","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16650805","The role of apoptosis in neuromuscular diseases and prospects for anti-apoptosis therapy.","16650805",42]
["MK0626","MK0626","C570834","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"25473177","MK-0626, a selective DPP-4 inhibitor, attenuates hepatic steatosis in ob/ob mice.","25473177",42]
["Molsidomine","Molsidomine","D008981","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20852057","The nitric oxide donor molsidomine rescues cardiac function in rats with chronic kidney disease and cardiac dysfunction.","20852057",42]
["Monocrotaline","Monocrotaline","D016686","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1993,"8502664","Regulation of kininogen gene expression and localization in the lung after monocrotaline-induced pulmonary hypertension in rats.","8502664",42]
["morin","morin","C008548","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28204816","Antioxidant and cytoprotective effects of morin against hydrogen peroxide-induced oxidative stress are associated with the induction of Nrf-2‑mediated HO-1 expression in V79-4 Chinese hamster lung fibroblasts.","28204816",42]
["Morphine","Morphine","D009020","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18614186","Delayed, context- and dopamine D1 receptor-dependent activation of ERK in morphine-sensitized mice.","18614186",42]
["Morphine","Morphine","D009020","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19656263","Supraspinal Gbetagamma-dependent stimulation of PLCbeta originating from G inhibitory protein-mu opioid receptor-coupling is necessary for morphine induced acute hyperalgesia.","19656263",42]
["Morphine","Morphine","D009020","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23623815","Region-specific expression of brain-derived neurotrophic factor splice variants in morphine conditioned place preference in mice.","23623815",42]
["Morphine","Morphine","D009020","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9838105","The 5-HT3 receptor antagonist, MDL 72222, dose-dependently potentiates morphine-induced immediate-early gene expression in the rat caudate putamen.","9838105",42]
["Mycobacterium tuberculosis antigens","Mycobacterium tuberculosis antigens","C072681","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"27892960","New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles.","27892960",42]
["Mycophenolic Acid","Mycophenolic Acid","D009173","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26274951","Osteoclast Differentiation Is Impaired in a Subgroup of SLE Patients and Correlates Inversely with Mycophenolate Mofetil Treatment.","26274951",42]
["N-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-1H-indazole-3-carboxamide hydrochloride","N-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-1H-indazole-3-carboxamide hydrochloride","C554954","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28174063","Use of early phenotypic in vivo markers to assess human relevance of an unusual rodent non-genotoxic carcinogen in vitro.","28174063",42]
["N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide","N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide","C063509","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11728449","Histamine increases the expression of LOX-1 via H2 receptor in human monocytic THP-1 cells.","11728449",42]
["N-(4-chloro-2-fluorophenyl)-2-hydroxybenzamide","N-(4-chloro-2-fluorophenyl)-2-hydroxybenzamide","C577570","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22396044","A benzamide-linked small molecule NDMC101 inhibits NFATc1 and NF-κB activity: a potential osteoclastogenesis inhibitor for experimental arthritis.","22396044",42]
["nabumetone","nabumetone","C035605","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2001,"11355956","Chemoprevention of intestinal tumorigenesis by nabumetone: induction of apoptosis and Bcl-2 downregulation.","11355956",42]
["Nacre","Nacre","D060734","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26231360","Identification of genes associated with shell color in the black-lipped pearl oyster, Pinctada margaritifera.","26231360",42]
["Naproxen","Naproxen","D009288","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"25747480","Anti-inflammatory and cytoprotective properties of hydrogen sulfide.","25747480",42]
["N-chlorotaurine","N-chlorotaurine","C043410","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25833491","Taurine Chloramine, a Taurine Metabolite from Activated Neutrophils, Inhibits Osteoclastogenesis by Suppressing NFATc1 Expression.","25833491",42]
["Neomycin","Neomycin","D009355","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2000,"11035925","The tkNeo gene, but not the pgkPuro gene, can influence the ability of the beta-globin LCR to enhance and confer position-independent expression onto the beta-globin gene.","11035925",42]
["Neutral Red","Neutral Red","D009499","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2006,"16182591","Neutral-red reaction is related to virulence and cell wall methyl-branched lipids in Mycobacterium tuberculosis.","16182591",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"12218105","Effects of nicotine exposure on T cell development in fetal thymus organ culture: arrest of T cell maturation.","12218105",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"16002786","A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1.","16002786",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2009,"19858493","Nicotine response genetics in the zebrafish.","19858493",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"26492471","Nighttime Administration of Nicotine Improves Hepatic Glucose Metabolism via the Hypothalamic Orexin System in Mice.","26492471",42]
["Nifedipine","Nifedipine","D009543","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15553663","Nifedipine inhibits gene expression of receptor for advanced glycation end products (RAGE) in endothelial cells by suppressing reactive oxygen species generation.","15553663",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2000,"11025451","Induction of MRP1 and gamma-glutamylcysteine synthetase gene expression by interleukin 1beta is mediated by nitric oxide-related signalings in human colorectal cancer cells.","11025451",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1999,"10505790","Nitric oxide regulates interleukin-8 gene expression in activated endothelium by inhibiting NF-kappaB binding to DNA: effects on endothelial function.","10505790",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2003,"12500260","Perturbations in paracrine control of the circulation: role of the endothelial-derived vasomediators, endothelin-1 and nitric oxide.","12500260",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"14742673","Nitric oxide regulates c-fos expression in nucleus tractus solitarii induced by baroreceptor activation via cGMP-dependent protein kinase and cAMP response element-binding protein phosphorylation.","14742673",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2004,"15465035","The inhibitory effect of sodium nitroprusside on HIF-1 activation is not dependent on nitric oxide-soluble guanylyl cyclase pathway.","15465035",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"16146339","L-methionine reduces oxidant stress in endothelial cells: role of heme oxygenase-1, ferritin, and nitric oxide.","16146339",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17548062","Attenuation of reperfusion injury by renal ischemic postconditioning: the role of NO.","17548062",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18459142","PARP-1 modulates deferoxamine-induced HIF-1alpha accumulation through the regulation of nitric oxide and oxidative stress.","18459142",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C38979,B38979)","v":"Nitric Oxide"},"Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J38979,K38979)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,1,2009,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q38979,Q38979)","v":"19351706"},"CEL-I, an N-acetylgalactosamine (GalNAc)-specific C-type lectin, induces nitric oxide production in RAW264.7 mouse macrophage cell line.","19351706",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20048197","Cyclin-dependent kinase 5 phosphorylates endothelial nitric oxide synthase at serine 116.","20048197",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C39107,B39107)","v":"Nitric Oxide"},"Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J39107,K39107)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,1,2012,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q39107,Q39107)","v":"23045614"},"Smad3-deficient CD11b(+)Gr1(+) myeloid-derived suppressor cells prevent allograft rejection via the nitric oxide pathway.","23045614",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23755229","Redox factor-1 activates endothelial SIRTUIN1 through reduction of conserved cysteine sulfhydryls in its deacetylase domain.","23755229",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"25342257","Inhibitory effects of extract from G. lanceolata on LPS-induced production of nitric oxide and IL-1β via down-regulation of MAPK in macrophages.","25342257",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26440402","Estrogen upregulates inflammatory signals through NF-κB, IFN-γ, and nitric oxide via Akt/mTOR pathway in the lymph node lymphocytes of middle-aged female rats.","26440402",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1993,"7694564","Should surgeons clone genes? The strategy behind the cloning of the human inducible nitric oxide synthase gene.","7694564",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9602069","The modulatory role of nitric oxide in the regulation of proenkephalin and prodynorphin gene expressions induced by kainic acid in rat hippocampus.","9602069",42]
["Nitroglycerin","Nitroglycerin","D005996","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"22066456","[Effect of tetrandrine on nitroglycerin induced activation of satellite cells in trigeminal ganglia].","22066456",42]
["nobiletin","nobiletin","C008661","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18261712","Sp1 is an essential transcription factor for LPS-induced tissue factor expression in THP-1 monocytic cells, and nobiletin represses the expression through inhibition of NF-kappaB, AP-1, and Sp1 activation.","18261712",42]
["nonylphenol","nonylphenol","C025256","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21914226","miRNA regulation of cytotoxic effects in mouse Sertoli cells exposed to nonylphenol.","21914226",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"12225877","Sex differences in the regulation of tyrosine hydroxylase gene transcription by estrogen in the locus coeruleus of TH9-LacZ transgenic mice.","12225877",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17690163","Contribution of noradrenergic and adrenergic cell groups of the brainstem and agouti-related protein-synthesizing neurons of the arcuate nucleus to neuropeptide-y innervation of corticotropin-releasing hormone neurons in hypothalamic paraventricular nucleus of the rat.","17690163",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1993,"8439325","Phosphorylation of an acid-soluble nuclear protein in response to catecholamine in cultured rat cardiocytes.","8439325",42]
["Norfloxacin","Norfloxacin","D009643","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25997556","Chitosan Influences the Expression of P-gp and Metabolism of Norfloxacin in Grass Carp.","25997556",42]
["N-tert-butylhydroxylamine","N-tert-butylhydroxylamine","C072771","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2005,"16438800","N-t-Butyl hydroxylamine regulates heat shock-induced apoptosis in U937 cells.","16438800",42]
["ochratoxin A","ochratoxin A","C025589","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17195275","Ochratoxin A: An overview on toxicity and carcinogenicity in animals and humans.","17195275",42]
["Okadaic Acid","Okadaic Acid","D019319","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1990,"1966042","Regulation of collagenase gene expression by okadaic acid, an inhibitor of protein phosphatases.","1966042",42]
["olanzapine","olanzapine","C076029","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26227793","Neuroleptics Affect Neuropeptide S and NPSR mRNA Levels in the Rat Brain.","26227793",42]
["Oleanolic Acid","Oleanolic Acid","D009828","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"23519253","Telomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancer.","23519253",42]
["oleocanthal","oleocanthal","C503534","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"23044226","Further evidence for the anti-inflammatory activity of oleocanthal: inhibition of MIP-1α and IL-6 in J774 macrophages and in ATDC5 chondrocytes.","23044226",42]
["Olive Oil","Olive Oil","D000069463","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"25733165","Virgin olive oil rich in phenolic compounds modulates the expression of atherosclerosis-related genes in vascular endothelium.","25733165",42]
["Omacor","Omacor","C405603","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20638067","Eicosapentaenoic acid (EPA) from highly concentrated n-3 fatty acid ethyl esters is incorporated into advanced atherosclerotic plaques and higher plaque EPA is associated with decreased plaque inflammation and increased stability.","20638067",42]
["opacity proteins","opacity proteins","C050308","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1987,"3130782","The control mechanism of opacity protein expression in the pathogenic Neisseriae.","3130782",42]
["Oxalic Acid","Oxalic Acid","D019815","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24628885","Immunohistochemical localization and mRNA quantification of osteopontin and Tamm-Horsfall protein in canine renal tissue after potassium oxalate injection.","24628885",42]
["Oxidopamine","Oxidopamine","D016627","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2003,"13678665","Targeted expression of BCL-2 attenuates MPP+ but not 6-OHDA induced cell death in dopaminergic neurons.","13678665",42]
["Oxidopamine","Oxidopamine","D016627","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28778432","Time-course of striatal Toll-like receptor expression in neurotoxic, environmental and inflammatory rat models of Parkinson's disease.","28778432",42]
["oxymatrine","oxymatrine","C037573","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20587445","Oxymatrine inhibits development of morphine-induced tolerance associated with decreased expression of P-glycoprotein in rats.","20587445",42]
["Paclitaxel","Paclitaxel","D017239","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"16718469","Paclitaxel nanoparticle inhibits growth of ovarian cancer xenografts and enhances lymphatic targeting.","16718469",42]
["Paclitaxel","Paclitaxel","D017239","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1995,"8521385","Microtubule-active drugs taxol, vinblastine, and nocodazole increase the levels of transcriptionally active p53.","8521385",42]
["Palmitic Acid","Palmitic Acid","D019308","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"11833041","Differential impact of acute and chronic lipotoxicity on gene expression in INS-1 cells.","11833041",42]
["Palmitic Acid","Palmitic Acid","D019308","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"23058789","Palmitic acid in chicken granulosa cell death-lipotoxic mechanisms mediate reproductive inefficacy of broiler breeder hens.","23058789",42]
["paraform","paraform","C003043","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24661843","Effects of hydroformylation treatment on the storage time and blood group antigen expressions of reagent red blood cells.","24661843",42]
["paricalcitol","paricalcitol","C084656","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"19948844","Vitamin D receptor activators induce an anticalcific paracrine program in macrophages: requirement of osteopontin.","19948844",42]
["Particulate Matter","Particulate Matter","D052638","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16762398","Dose-controlled exposure of A549 epithelial cells at the air-liquid interface to airborne ultrafine carbonaceous particles.","16762398",42]
["Particulate Matter","Particulate Matter","D052638","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"27041089","Direct effects of airborne PM2.5 exposure on macrophage polarizations.","27041089",42]
["PCERA-1","PCERA-1","C541330","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"26656944","Exogenous ceramide-1-phosphate (C1P) and phospho-ceramide analogue-1 (PCERA-1) regulate key macrophage activities via distinct receptors.","26656944",42]
["pentabromodiphenyl ether","pentabromodiphenyl ether","C086401","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18550172","Exposure to brominated flame retardant PBDE-99 affects cytoskeletal protein expression in the neonatal mouse cerebral cortex.","18550172",42]
["Pentoxifylline","Pentoxifylline","D010431","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2003,"12642397","Inhibition by pentoxifylline of TNF-alpha-stimulated fractalkine production in vascular smooth muscle cells: evidence for mediation by NF-kappa B down-regulation.","12642397",42]
["perfluorononanoic acid","perfluorononanoic acid","C584865","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25181679","Integrated proteomic and miRNA transcriptional analysis reveals the hepatotoxicity mechanism of PFNA exposure in mice.","25181679",42]
["perfluorooctane sulfonic acid","perfluorooctane sulfonic acid","C076994","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"26724606","Hepatic miRNA profiles and thyroid hormone homeostasis in rats exposed to dietary potassium perfluorooctanesulfonate (PFOS).","26724606",42]
["Permethrin","Permethrin","D026023","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20143453","Splice variant specific increase in Ca2+/calmodulin-dependent protein kinase 1-gamma mRNA expression in response to acute pyrethroid exposure.","20143453",42]
["Perylene","Perylene","D010569","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"12240952","Relative quantification of mRNA levels in Jurkat T cells with RT-real time-PCR (RT-rt-PCR): new possibilities for the screening of anti-inflammatory and cytotoxic compounds.","12240952",42]
["Phencyclidine","Phencyclidine","D010622","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11377837","Differential regulation of chromogranin A, chromogranin B and secretogranin II in rat brain by phencyclidine treatment.","11377837",42]
["Phenobarbital","Phenobarbital","D010634","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2005,"15572372","AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line.","15572372",42]
["Phenobarbital","Phenobarbital","D010634","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1988,"3356413","Phenobarbital induction of cytochrome P-450 b,e genes is dependent on protein synthesis.","3356413",42]
["Phenylglyoxal","Phenylglyoxal","D010658","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2002,"12029367","Modulation of renal type IIa Na+/Pi cotransporter kinetics by the arginine modifier phenylglyoxal.","12029367",42]
["phloretamide","phloretamide","C581533","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23063670","Phloretamide, an apple phenolic compound, activates the Nrf2/ARE pathway in human hepatocytes.","23063670",42]
["Phorbol 12,13-Dibutyrate","Phorbol 12,13-Dibutyrate","D015240","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1987,"3114365","Requirements for the simultaneous presence of phorbol esters and calcium ionophores in the expression of human T lymphocyte proliferation-related genes.","3114365",42]
["phosphatidylinositol 3-phosphate","phosphatidylinositol 3-phosphate","C055525","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23154468","Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration.","23154468",42]
["phosphatidylinositol 4-phosphate","phosphatidylinositol 4-phosphate","C037178","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2001,"11706203","Arabidopsis dynamin-like 2 that binds specifically to phosphatidylinositol 4-phosphate assembles into a high-molecular weight complex in vivo and in vitro.","11706203",42]
["phytosphingosine","phytosphingosine","C012491","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2004,"14722105","Sphingolipids as bioactive regulators of thrombin generation.","14722105",42]
["Pilocarpine","Pilocarpine","D010862","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"16023256","Tonic-clonic seizures induce division of neuronal progenitor cells with concomitant changes in expression of neurotrophic factors in the brain of pilocarpine-treated mice.","16023256",42]
["pioglitazone","pioglitazone","C060836","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17327450","Effects of pioglitazone on suppressor of cytokine signaling 3 expression: potential mechanisms for its effects on insulin sensitivity and adiponectin expression.","17327450",42]
["pioglitazone","pioglitazone","C060836","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26035752","Effect of Chronic Pioglitazone Treatment on Hepatic Gene Expression Profile in Obese C57BL/6J Mice.","26035752",42]
["pirarubicin","pirarubicin","C027260","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1997,"9389578","Evidence for reversal of multidrug resistance by quinine in LR73 cells without alteration of nuclear pirarubicin uptake and down-regulation of mdr1 gene expression.","9389578",42]
["pirinixic acid","pirinixic acid","C006253","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"17495861","A role of liver fatty acid-binding protein in cisplatin-induced acute renal failure.","17495861",42]
["pitavastatin","pitavastatin","C108475","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21521932","Pitavastatin increases ABCA1 expression by dual mechanisms: SREBP2-driven transcriptional activation and PPARα-dependent protein stabilization but without activating LXR in rat hepatoma McARH7777 cells.","21521932",42]
["Platelet Activating Factor","Platelet Activating Factor","D010972","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1994,"7821968","Platelet-activating factor and endotoxin induce tumour necrosis factor gene expression in rat intestine and liver.","7821968",42]
["PMK-S005","PMK-S005","C000594566","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"25283375","Protective effects of garlic extract, PMK-S005, against nonsteroidal anti-inflammatory drugs-induced acute gastric damage in rats.","25283375",42]
["poly(3,4-ethylene dioxythiophene)","poly(3,4-ethylene dioxythiophene)","C121383","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2012,"22944870","Directed differentiation of embryonic P19 cells and neural stem cells into neural lineage on conducting PEDOT-PEG and ITO glass substrates.","22944870",42]
["polycaprolactone","polycaprolactone","C016240","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25449121","Injectable radiopaque and bioactive polycaprolactone-ceramic composites for orthopedic augmentation.","25449121",42]
["Polyethyleneimine","Polyethyleneimine","D011094","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2009,"19442462","High mobility group box 1 protein enhances polyethylenimine mediated gene delivery in vitro.","19442462",42]
["Polyglycolic Acid","Polyglycolic Acid","D011100","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23335380","The compatibility of swine BMDC-derived bile duct endothelial cells with a nanostructured electrospun PLGA material.","23335380",42]
["Polyglycolic Acid","Polyglycolic Acid","D011100","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27326916","Investigation of angiogenesis in bioactive 3-dimensional poly(d,l-lactide-co-glycolide)/nano-hydroxyapatite scaffolds by in vivo multiphoton microscopy in murine calvarial critical bone defect.","27326916",42]
["Polytetrafluoroethylene","Polytetrafluoroethylene","D011138","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18067190","Cytobiocompatibility of collagen and ePTFE membranes on osteoblast-like cells in vitro.","18067190",42]
["Potassium Chloride","Potassium Chloride","D011189","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15654839","The actin-binding protein profilin I is localized at synaptic sites in an activity-regulated manner.","15654839",42]
["Pravastatin","Pravastatin","D017035","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16565312","Additive effects of combined blockade of AT1 receptor and HMG-CoA reductase on left ventricular remodeling in infarcted rats.","16565312",42]
["Prednisolone","Prednisolone","D011239","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"16901990","Prednisolone-induced Ca2+ malabsorption is caused by diminished expression of the epithelial Ca2+ channel TRPV6.","16901990",42]
["proanthocyanidin","proanthocyanidin","C013221","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28672844","5-(3',4'-Dihydroxyphenyl-γ-valerolactone), a Major Microbial Metabolite of Proanthocyanidin, Attenuates THP-1 Monocyte-Endothelial Adhesion.","28672844",42]
["procyanidin B2","procyanidin B2","C479580","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28088699","Procyanidin B2 gallates inhibit IFN-γ and IL-17 production in T cells by suppressing T-bet and RORγt expression.","28088699",42]
["Propofol","Propofol","D015742","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2005,"15965071","Anti-inflammatory and antioxidative effects of propofol on lipopolysaccharide-activated macrophages.","15965071",42]
["Propofol","Propofol","D015742","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26023717","Anesthetic propofol overdose causes vascular hyperpermeability by reducing endothelial glycocalyx and ATP production.","26023717",42]
["Prostaglandin D2","Prostaglandin D2","D015230","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2002,"11801678","15-deoxy-Delta 12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway.","11801678",42]
["Prostaglandin D2","Prostaglandin D2","D015230","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18258196","Central prostaglandin D(2) stimulates food intake via the neuropeptide Y system in mice.","18258196",42]
["prostaglandin E2 ethanolamide","prostaglandin E2 ethanolamide","C107684","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2008,"17961121","Anandamide inhibits IL-12p40 production by acting on the promoter repressor element GA-12: possible involvement of the COX-2 metabolite prostamide E(2).","17961121",42]
["prostratin","prostratin","C070999","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27529070","HMBA Enhances Prostratin-Induced Activation of Latent HIV-1 via Suppressing the Expression of Negative Feedback Regulator A20/TNFAIP3 in NF-κB Signaling.","27529070",42]
["puerarin","puerarin","C033607","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26330232","Puerarin Suppresses the Self-Renewal of Murine Embryonic Stem Cells by Inhibition of REST-MiR-21 Regulatory Pathway.","26330232",42]
["Pyocyanine","Pyocyanine","D011710","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16819965","Pseudomonas aeruginosa pyocyanin inactivates lung epithelial vacuolar ATPase-dependent cystic fibrosis transmembrane conductance regulator expression and localization.","16819965",42]
["Pyridoxal Phosphate","Pyridoxal Phosphate","D011732","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2004,"15155383","Enhanced P2X7 activity in human fibroblasts from diabetic patients: a possible pathogenetic mechanism for vascular damage in diabetes.","15155383",42]
["qianlieantong","qianlieantong","C532631","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"19157134","[Influence of Qianlie Antong tablets on expresstion of VEGF and bFGF in protatic tissues of BHP rats].","19157134",42]
["Quercetin","Quercetin","D011794","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17855110","Quercetin 3-O-beta-(2''-galloyl)-glucopyranoside inhibits endotoxin LPS-induced IL-6 expression and NF-kappa B activation in macrophages.","17855110",42]
["Quercetin","Quercetin","D011794","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21624509","Hepatoprotection of quercetin against oxidative stress by induction of metallothionein expression through activating MAPK and PI3K pathways and enhancing Nrf2 DNA-binding activity.","21624509",42]
["Quercetin","Quercetin","D011794","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28146071","Actions of Quercetin, a Polyphenol, on Blood Pressure.","28146071",42]
["Quinic Acid","Quinic Acid","D011801","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2003,"12695850","Quinic acid induces hypovirulence and expression of a hypovirulence-associated double-stranded RNA in Rhizoctonia solani.","12695850",42]
["Quinolinic Acid","Quinolinic Acid","D017378","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19526301","Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons.","19526301",42]
["Raloxifene Hydrochloride","Raloxifene Hydrochloride","D020849","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2000,"10809227","Antiestrogens specifically up-regulate bone morphogenetic protein-4 promoter activity in human osteoblastic cells.","10809227",42]
["RepSox","RepSox","C550621","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28247195","RepSox improves viability and regulates gene expression in rhesus monkey-pig interspecies cloned embryos.","28247195",42]
["resolvin D1","resolvin D1","C518399","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26335632","In vitro effects of docosahexaenoic and eicosapentaenoic acid on human meibomian gland epithelial cells.","26335632",42]
["resveratrol","resveratrol","C059514","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"17236591","[The study in resveratrol function to acute lung injury sourced from severe acute pancreatitis].","17236591",42]
["resveratrol","resveratrol","C059514","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"20041738","Consuming a diet supplemented with resveratrol reduced infection-related neuroinflammation and deficits in working memory in aged mice.","20041738",42]
["resveratrol","resveratrol","C059514","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24740756","Redox regulation of antioxidant enzymes: post-translational modulation of catalase and glutathione peroxidase activity by resveratrol in diabetic rat liver.","24740756",42]
["resveratrol","resveratrol","C059514","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26348076","Effect of fluoxetine and resveratrol on testicular functions and oxidative stress in a rat model of chronic mild stress-induced depression.","26348076",42]
["resveratrol","resveratrol","C059514","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27399675","The Effect of Resveratrol and Quercetin Treatment on PPAR Mediated Uncoupling Protein (UCP-) 1, 2, and 3 Expression in Visceral White Adipose Tissue from Metabolic Syndrome Rats.","27399675",42]
["Retinaldehyde","Retinaldehyde","D012172","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"25138066","Hyalurosome gene regulation and dose-dependent restoration of skin atrophy by retinaldehyde and defined-size hyaluronate fragments in dermatoporosis.","25138066",42]
["rhodioloside","rhodioloside","C009172","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"24055767","Salidroside stimulates osteoblast differentiation through BMP signaling pathway.","24055767",42]
["Rifampin","Rifampin","D012293","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"18075461","Effects of rifampicin on global gene expression in human small intestine.","18075461",42]
["Risperidone","Risperidone","D018967","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2000,"11106001","The effect of the antipsychotic drug mosapramine on the expression of Fos protein in the rat brain: comparison with haloperidol, clozapine and risperidone.","11106001",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C44163,B44163)","v":"Ro 25-6760"},"Ro 25-6760","C113532","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J44163,K44163)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,1,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q44163,Q44163)","v":"15590756"},"1,25 dihydroxyvitamin d amplifies type a natriuretic peptide receptor expression and activity in target cells.","15590756",42]
["rosiglitazone","rosiglitazone","C089730","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2003,"14595539","Rosiglitazone produces insulin sensitisation by increasing expression of the insulin receptor and its tyrosine kinase activity in brown adipocytes.","14595539",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C44291,B44291)","v":"rosiglitazone"},"rosiglitazone","C089730","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J44291,K44291)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,2,2007,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q44291,Q44291)","v":"17310221"},"Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1 alpha and PPAR beta/delta gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus.","17310221",42]
["rosiglitazone","rosiglitazone","C089730","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21839072","Metformin prevents anti-osteogenic in vivo and ex vivo effects of rosiglitazone in rats.","21839072",42]
["rosiglitazone","rosiglitazone","C089730","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26061913","PPARγ Agonists Attenuate Palmitate-Induced ER Stress through Up-Regulation of SCD-1 in Macrophages.","26061913",42]
["Rosuvastatin Calcium","Rosuvastatin Calcium","D000068718","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27097221","Beneficial Effects of Sarpogrelate and Rosuvastatin in High Fat Diet/Streptozotocin-Induced Nephropathy in Mice.","27097221",42]
["rupatadine","rupatadine","C103639","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"25443720","Rupatadine effectively prevents the histamine-induced up regulation of histamine H1R and bradykinin B2R receptor gene expression in the rat paw.","25443720",42]
["Safflower Oil","Safflower Oil","D012450","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"16713235","Changes in liver PPARalpha mRNA expression in response to two levels of high-safflower-oil diets correlate with changes in adiposity and serum leptin in rats and mice.","16713235",42]
["salubrinal","salubrinal","C496827","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27678416","Salubrinal attenuates right ventricular hypertrophy and dysfunction in hypoxic pulmonary hypertension of rats.","27678416",42]
["Santalin","Santalin","C030275","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"26828288","Functionality study of santalin as tyrosinase inhibitor: A potential depigmentation agent.","26828288",42]
["sarafotoxins s6","sarafotoxins s6","C057354","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20802974","Modulation of rhodopsin gene expression and signaling mechanisms evoked by endothelins in goldfish and murine pigment cell lines.","20802974",42]
["SB-611812","SB-611812","C513816","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16797584","Urotensin-II blockade with SB-611812 attenuates cardiac dysfunction in a rat model of coronary artery ligation.","16797584",42]
["senkyunolide I","senkyunolide I","C576743","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"26950101","Elucidation of Transport Mechanism of Paeoniflorin and the Influence of Ligustilide, Senkyunolide I and Senkyunolide A on Paeoniflorin Transport through Mdck-Mdr1 Cells as Blood-Brain Barrier in Vitro Model.","26950101",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2000,"10632606","BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain.","10632606",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"14997015","Role of serotonin on cocaine-mediated effects on prodynorphin gene expression in the rat brain.","14997015",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17513084","An in vitro study on 5-HT6 receptor antagonist induced hepatotoxicity based on biochemical assays and toxicogenomics.","17513084",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20796171","5-HT2C receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: modulation by chronic paroxetine treatment.","20796171",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22494991","Decision time and perseveration of adolescent rats in the T-maze are affected differentially by buspirone and independent of 5-HT-1A expression.","22494991",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23929722","Nonivamide, a capsaicin analog, increases dopamine and serotonin release in SH-SY5Y cells via a TRPV1-independent pathway.","23929722",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1997,"9015328","Ketanserin selectively blocks acute stress-induced changes in NGFI-A and mineralocorticoid receptor gene expression in hippocampal neurons.","9015328",42]
["sesamol","sesamol","C025583","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19565232","Administration of sesamol improved blood-brain barrier function in streptozotocin-induced diabetic rats.","19565232",42]
["sevoflurane","sevoflurane","C009250","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26700589","Influence of neonatal sevoflurane exposure on nerve development-related microRNAs and behavior of rats.","26700589",42]
["shosaikoto-go-keishika-shakuyakuto","shosaikoto-go-keishika-shakuyakuto","C461321","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1999,"11485047","Regulation of gene expression by herbal medicines--a new paradigm of gene therapy for multifocal abnormalities of genes.","11485047",42]
["Silicon Dioxide","Silicon Dioxide","D012822","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22835726","Inflammatory and degranulation effect of yellow sand on RBL-2H3 cells in relation to chemical and biological constituents.","22835726",42]
["silybin","silybin","C440975","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23851051","Down-regulation of LPCAT expression increases platelet-activating factor level in cirrhotic rat liver: potential antiinflammatory effect of silybin.","23851051",42]
["Simvastatin","Simvastatin","D019821","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15337740","Statin induction of liver fatty acid-binding protein (L-FABP) gene expression is peroxisome proliferator-activated receptor-alpha-dependent.","15337740",42]
["Simvastatin","Simvastatin","D019821","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"20508068","Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression.","20508068",42]
["Simvastatin","Simvastatin","D019821","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28864210","Inhibition of the mevalonate pathway by simvastatin interferes with mast cell degranulation by disrupting the interaction between Rab27a and double C2 alpha proteins.","28864210",42]
["Sirolimus","Sirolimus","D020123","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2003,"12684373","Rapamycin mimics the incompatibility reaction in the fungus Podospora anserina.","12684373",42]
["Sirolimus","Sirolimus","D020123","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17277121","A role for mammalian target of rapamycin in regulating T cell activation versus anergy.","17277121",42]
["Sirolimus","Sirolimus","D020123","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21876130","The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile.","21876130",42]
["Sirolimus","Sirolimus","D020123","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1996,"8668994","Protein matchmaker may lead new gene therapy to the altar.","8668994",42]
["Smoke","Smoke","D012906","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1999,"10069490","Modified natural porcine surfactant modulates tobacco smoke-induced stress response in human monocytes.","10069490",42]
["Smoke","Smoke","D012906","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20504369","Inhibition of IFN-gamma-dependent antiviral airway epithelial defense by cigarette smoke.","20504369",42]
["sobuzoxane","sobuzoxane","C057773","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1994,"8012276","bis(2,6-dioxopiperaxine) derivatives, topoisomerase II inhibitors which do not form a DNA cleavable complex, induce thymocyte apoptosis.","8012276",42]
["sodium arsenite","sodium arsenite","C017947","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2003,"12679051","Low-level arsenite induced gene expression in HEK293 cells.","12679051",42]
["sodium bichromate","sodium bichromate","C016104","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24612858","Whole adult organism transcriptional profiling of acute metal exposures in male zebrafish.","24612858",42]
["Sodium Chloride","Sodium Chloride","D012965","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19167465","NaCl responsive taste cells in the mouse fungiform taste buds.","19167465",42]
["Sodium Cyanide","Sodium Cyanide","D012966","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1995,"7760376","Regulated expression of a contractile protein gene correlates with recovery of contractile function after reversible metabolic inhibition in cultured myocytes.","7760376",42]
["Sodium Fluoride","Sodium Fluoride","D012969","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2018,"29414353","The toxic effect of sodium fluoride on Spodoptera frugiperda 9 cells and differential protein analysis following NaF treatment of cells.","29414353",42]
["Sodium Selenite","Sodium Selenite","D018038","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2004,"15158026","Glutamate-induced cell death of immortalized murine hippocampal neurons: neuroprotective activity of heme oxygenase-1, heat shock protein 70, and sodium selenite.","15158026",42]
["Sodium, Dietary","Sodium, Dietary","D012982","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26028245","Genomics and Pharmacogenomics of Salt-sensitive Hypertension.","26028245",42]
["soybean oil, phospholipid emulsion","soybean oil, phospholipid emulsion","C545823","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25524913","Lipid-induced insulin resistance is associated with an impaired skeletal muscle protein synthetic response to amino acid ingestion in healthy young men.","25524913",42]
["Spermine","Spermine","D013096","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16221492","Dextran-spermine-based polyplexes--evaluation of transgene expression and of local and systemic toxicity in mice.","16221492",42]
["Sphingosine","Sphingosine","D013110","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15715670","Extracellular release of newly synthesized sphingosine-1-phosphate by cerebellar granule cells and astrocytes.","15715670",42]
["Sphingosine","Sphingosine","D013110","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22819712","Posttranscriptional regulation of expression of plasminogen activator inhibitor type-1 by sphingosine 1-phosphate in HepG2 liver cells.","22819712",42]
["sphingosine 1-phosphate","sphingosine 1-phosphate","C060506","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1999,"10640689","Sphingosine 1-phosphate induces expression of early growth response-1 and fibroblast growth factor-2 through mechanism involving extracellular signal-regulated kinase in astroglial cells.","10640689",42]
["sphingosine 1-phosphate","sphingosine 1-phosphate","C060506","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"17341687","The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing.","17341687",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C46723,B46723)","v":"sphingosine 1-phosphate"},"sphingosine 1-phosphate","C060506","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J46723,K46723)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,2,2014,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q46723,Q46723)","v":"25041788"},"Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells.","25041788",42]
["Spironolactone","Spironolactone","D013148","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17587755","Spironolactone modulates expressions of cardiac mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase 2 and prevents ventricular remodeling in post-infarct rat hearts.","17587755",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C46851,B46851)","v":"Starch"},"Starch","D013213","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J46851,K46851)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,1,2011,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q46851,Q46851)","v":"22293211"},"Raw Chinese yam (Dioscorea opposita) promotes cecal fermentation and reduces plasma non-HDL cholesterol concentration in rats.","22293211",42]
["Staurosporine","Staurosporine","D019311","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9585168","Cloning of bovine preproadrenomedullin and inhibition of its basal expression in vascular endothelial cells by staurosporine.","9585168",42]
["Stigmasterol","Stigmasterol","D013265","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"23074702","Stigmasterol blocks cartilage degradation in rabbit model of osteoarthritis.","23074702",42]
["Sucrose","Sucrose","D013395","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18627777","Effects of sucrose, glucose and fructose on peripheral and central appetite signals.","18627777",42]
["sulforafan","sulforafan","C016766","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23441612","Identification of microRNAs regulated by isothiocyanates and association of polymorphisms inside their target sites with risk of sporadic colorectal cancer.","23441612",42]
["Sulfur Dioxide","Sulfur Dioxide","D013458","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"17962899","Effects of sulfur dioxide on the expressions of EGF, EGFR, and COX-2 in airway of asthmatic rats.","17962899",42]
["sunitinib","sunitinib","C473478","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"25013907","Association of toxicity of sorafenib and sunitinib for human keratinocytes with inhibition of signal transduction and activator of transcription 3 (STAT3).","25013907",42]
["Tacrolimus","Tacrolimus","D016559","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"15857611","Protective effect of FK506 against apoptosis of SH-SY5Y cells correlates with regulation of the serum inducible kinase gene.","15857611",42]
["Tacrolimus","Tacrolimus","D016559","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2011,"21515370","Effects of a calcineurin inhibitor, FK506, and a CCR5/CXCR3 antagonist, TAK-779, in a rat small intestinal transplantation model.","21515370",42]
["Tacrolimus","Tacrolimus","D016559","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1997,"9442391","Effects of the immunosuppressive drugs CsA and FK506 on intracellular signalling and gene regulation.","9442391",42]
["Tamoxifen","Tamoxifen","D013629","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17905229","Inducible gene expression in the lens using tamoxifen and a GFP reporter.","17905229",42]
["Tamoxifen","Tamoxifen","D013629","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"26304810","Effects of tamoxifen on autosomal genes regulating ovary maintenance in adult mice.","26304810",42]
["tanespimycin","tanespimycin","C112765","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2016,"27045471","NAD(P)H:Quinone Oxidoreductase-1 Expression Sensitizes Malignant Melanoma Cells to the HSP90 Inhibitor 17-AAG.","27045471",42]
["tanshinone II A sodium sulfonate","tanshinone II A sodium sulfonate","C024894","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28294475","Sodium tanshinone IIA sulfonate prevents hypoxic trophoblast-induced endothelial cell dysfunction via targeting HMGB1 release.","28294475",42]
["Taurocholic Acid","Taurocholic Acid","D013656","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2004,"15209631","Taurocholate transport by hepatic and intestinal bile acid transporters is independent of FIC1 overexpression in Madin-Darby canine kidney cells.","15209631",42]
["Tea","Tea","D013662","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1999,"10415792","Inhibition of matrix metalloproteinases by tea catechins and related polyphenols.","10415792",42]
["Tea","Tea","D013662","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2011,"21821246","Green tea epigallocatechin-3-gallate inhibits angiogenesis and suppresses vascular endothelial growth factor C/vascular endothelial growth factor receptor 2 expression and signaling in experimental endometriosis in vivo.","21821246",42]
["teflubenzuron","teflubenzuron","C052595","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28939506","Impact of teflubenzuron on the rockpool shrimp (Palaemon elegans).","28939506",42]
["Terbutaline","Terbutaline","D013726","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"19880505","Long-term terbutaline exposure stimulates alpha1-Na+-K+-ATPase expression at posttranscriptional level in rat fetal distal lung epithelial cells.","19880505",42]
["tetrabromobisphenol A","tetrabromobisphenol A","C020806","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19457453","Anti-thyroid hormone activity of bisphenol A, tetrabromobisphenol A and tetrachlorobisphenol A in an improved reporter gene assay.","19457453",42]
["Tetracycline","Tetracycline","D013752","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1999,"10618644","Homogeneous tetracycline-regulatable gene expression in mammalian fibroblasts.","10618644",42]
["Tetracycline","Tetracycline","D013752","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2002,"12467990","Targeting of a tetracycline-inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei.","12467990",42]
["Tetracycline","Tetracycline","D013752","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"24678266","Development of β -lactamase as a tool for monitoring conditional gene expression by a tetracycline-riboswitch in Methanosarcina acetivorans.","24678266",42]
["Tetracycline","Tetracycline","D013752","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1984,"6395803","Expression and loss of the pBR322 plasmid in Klebsiella aerogenes NCTC 418, grown in chemostat culture.","6395803",42]
["Tetracycline","Tetracycline","D013752","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9741432","Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells.","9741432",42]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2003,"14506241","DNase I hypersensitivity patterns of the serglycin proteoglycan gene in resting and phorbol 12-myristate 13-acetate-stimulated human erythroleukemia (HEL), CHRF 288-11, and HL-60 cells compared with neutrophils and human umbilical vein endothelial cells.","14506241",42]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1991,"1713607","Activation of AP-1 by IL-1 and phorbol esters in T cells. Role of protein kinase A and protein phosphatases.","1713607",42]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1990,"2118245","Activation of the serum-response and TPA-response elements by expression of the v-abl protein: comparison of the mode of action of the v-abl protein with those of protein kinase C, cyclic AMP-dependent protein kinase, and the activated c-raf protein.","2118245",42]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1988,"2467914","Relationship of cellular oncogene expression to inhibition of growth and induction of differentiation of Daudi cells by interferons or TPA.","2467914",42]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1986,"3790579","Changes in polypeptide synthesis and glycosylation in mouse embryonic fibroblast C3H/10T1/2 Cl 8 cells caused by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.","3790579",42]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1994,"7919377","Regulation of intercellular adhesion molecule-1 gene expression involves multiple mRNA stabilization mechanisms: effects of interferon-gamma and phorbol myristate acetate.","7919377",42]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1993,"8472849","Platelet derived growth factor-A chain gene expression in cultured mesangial cells: regulation by phorbol ester at the level of mRNA abundance, transcription and mRNA stability.","8472849",42]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9603451","PMA/ionomycin induces Ig kappa 3' enhancer activity which is in part mediated by a unique NFAT transcription complex.","9603451",42]
["Thalidomide","Thalidomide","D013792","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22098296","Role of vascular endothelial growth factor in angiodysplasia: an interventional study with thalidomide.","22098296",42]
["Thapsigargin","Thapsigargin","D019284","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20814750","Overexpression of ornithine decarboxylase suppresses thapsigargin-induced apoptosis.","20814750",42]
["Theophylline","Theophylline","D013806","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"28188783","Disruption of melanosome transport in melanocytes treated with theophylline causes their degradation by autophagy.","28188783",42]
["Thioctic Acid","Thioctic Acid","D008063","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23608068","Lipoic acid prevents Cr(6+) induced cell transformation and the associated genomic dysregulation.","23608068",42]
["Thiourea","Thiourea","D013890","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2002,"11919081","Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species.","11919081",42]
["Thymol","Thymol","D013943","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25889654","Impact of dietary organic acids and botanicals on intestinal integrity and inflammation in weaned pigs.","25889654",42]
["Tiantai No.1","Tiantai No.1","C548800","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2015,"25081895","Effect of Tiantai No.1 on gene expression profiles in hippocampus of Alzheimer's disease rats by bioinformatic analysis.","25081895",42]
["Tobacco Smoke Pollution","Tobacco Smoke Pollution","D014028","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2010,"20890690","Maternal and neonatal exposure to environmental tobacco smoke targets pro-inflammatory genes in neonatal arteries.","20890690",42]
["Tobacco Smoke Pollution","Tobacco Smoke Pollution","D014028","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27480279","In vitro model adapted to the study of skin ageing induced by air pollution.","27480279",42]
["Toluene","Toluene","D014050","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1985,"4008443","TOL plasmid pWW15 contains two nonhomologous, independently regulated catechol 2,3-oxygenase genes.","4008443",42]
["tranilast","tranilast","C012293","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2002,"12466360","Tranilast inhibits the proliferation of uterine leiomyoma cells in vitro through G1 arrest associated with the induction of p21(waf1) and p53.","12466360",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1999,"10328955","Dysregulated expression of cyclin D1 in normal human mammary epithelial cells inhibits all-trans-retinoic acid-mediated G0/G1-phase arrest and differentiation in vitro.","10328955",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2001,"11430695","Retinoic acid specifically downregulates Fgf4 and inhibits posterior cell proliferation in the developing mouse autopod.","11430695",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C49283,B49283)","v":"Tretinoin"},"Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J49283,K49283)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,1,2002,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q49283,Q49283)","v":"12397370"},"Retinoic acid enhances leukemia inhibitory factor expression in OLN-93 oligodendrocytes.","12397370",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1992,"1320257","Characterization of a retinoic acid responsive element isolated by whole genome PCR.","1320257",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C49411,B49411)","v":"Tretinoin"},"Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J49411,K49411)","v":"Gene Expression Regulation"},"D005786","Gene Expression Regulation",1,2,2005,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q49411,Q49411)","v":"16249480"},"Effect of retinoic acid on gene expression in human conjunctival epithelium: secretory phospholipase A2 mediates retinoic acid induction of MUC16.","16249480",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2006,"16873554","Regulation of progranulin expression in myeloid cells.","16873554",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"17975308","All-trans retinoic acid increases oxidative metabolism in mature adipocytes.","17975308",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19094985","All-trans retinoic acid remodels extracellular matrix and suppresses laminin-enhanced contractility of cultured human retinal pigment epithelial cells.","19094985",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1990,"2172788","Transcription factor Sp1 is important for retinoic acid-induced expression of the tissue plasminogen activator gene during F9 teratocarcinoma cell differentiation.","2172788",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23613978","Csn3 gene is regulated by all-trans retinoic acid during neural differentiation in mouse P19 cells.","23613978",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"26125906","WY14643 combined with all-trans retinoic acid acts via p38 MAPK to induce \"browning\" of white adipocytes in mice.","26125906",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"26654743","Retinoic acid and retinaldehyde dehydrogenase are not involved in the specific induction of the follicle-stimulating hormone β subunit by trichostatin A, a selective inhibitor of histone deacetylase.","26654743",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1995,"7558253","Retinoic acid-regulated cellular differentiation and mucin gene expression in isolated rabbit tracheal-epithelial cells in culture.","7558253",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1994,"7925656","Delayed activation of HNF-3 beta upon retinoic acid-induced teratocarcinoma cell differentiation.","7925656",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1993,"8395017","Retinoid X receptors stimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitamin D3-activated expression of the rat osteocalcin gene.","8395017",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9597752","Forced expression of hic-5, a senescence-related gene, potentiates a differentiation process of RCT-1 cells induced by retinoic acid.","9597752",42]
["Tretinoin","Tretinoin","D014212","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1998,"9891988","9-cis retinoic acid induces the expression of the uncoupling protein-2 gene in brown adipocytes.","9891988",42]
["tributyltin","tributyltin","C011559","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19577312","Inhibition of thyroidal status related to depression of testicular development in Sebastiscus marmoratus exposed to tributyltin.","19577312",42]
["trichostatin A","trichostatin A","C012589","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"16149071","Histone acetylase inhibitor trichostatin A induces acetylcholinesterase expression and protects against organophosphate exposure.","16149071",42]
["trichostatin A","trichostatin A","C012589","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24486299","Trichostatin A increases the levels of plasma gelsolin and amyloid beta-protein in a transgenic mouse model of Alzheimer's disease.","24486299",42]
["Triclosan","Triclosan","D014260","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28575748","Effects of triclosan (TCS) on fecundity, the antioxidant system, and oxidative stress-mediated gene expression in the copepod Tigriopus japonicus.","28575748",42]
["trioctyl trimellitate","trioctyl trimellitate","C034367","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"26650799","Transcriptome profiling and pathway analysis of hepatotoxicity induced by tris (2-ethylhexyl) trimellitate (TOTM) in mice.","26650799",42]
["tripalmitin","tripalmitin","C005859","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1995,"7626061","Regulation of hamster hepatic microsomal triglyceride transfer protein mRNA levels by dietary fats.","7626061",42]
["troglitazone","troglitazone","C057693","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1999,"10076998","A novel method for analysis of nuclear receptor function at natural promoters: peroxisome proliferator-activated receptor gamma agonist actions on aP2 gene expression detected using branched DNA messenger RNA quantitation.","10076998",42]
["troglitazone","troglitazone","C057693","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2003,"12613669","Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells.","12613669",42]
["trophoblast-lymphocyte cross-reactive antigens","trophoblast-lymphocyte cross-reactive antigens","C055067","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1989,"2508707","Trophoblast antigen expression.","2508707",42]
["Ubiquinone","Ubiquinone","D014451","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2010,"20526342","4-Nitrobenzoate inhibits coenzyme Q biosynthesis in mammalian cell cultures.","20526342",42]
["udenafil","udenafil","C419664","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2007,"17137605","Microarray analysis of gene expression profile in the corpus cavernosum of hypercholesterolemic rats after chronic treatment with PDE5 inhibitor.","17137605",42]
["Uranyl Nitrate","Uranyl Nitrate","D014502","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2009,"19409444","Heavy metal uranium affects the brain cholinergic system in rat following sub-chronic and chronic exposure.","19409444",42]
["Urea","Urea","D014508","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23495168","The effect of stress on gill basolateral membrane binding kinetics of 5-ht2 receptor ligands: potential implications for urea excretion mechanisms.","23495168",42]
["Ursodeoxycholic Acid","Ursodeoxycholic Acid","D014580","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"23764895","Defective canalicular transport and toxicity of dietary ursodeoxycholic acid in the abcb11-/- mouse: transport and gene expression studies.","23764895",42]
["ursolic acid","ursolic acid","C005466","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27085898","Ursolic acid induced anti-proliferation effects in rat primary vascular smooth muscle cells is associated with inhibition of microRNA-21 and subsequent PTEN/PI3K.","27085898",42]
["Valproic Acid","Valproic Acid","D014635","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2008,"18657526","Paliperidone as a mood stabilizer: a pre-frontal cortex synaptoneurosomal proteomics comparison with lithium and valproic acid after chronic treatment reveals similarities in protein expression.","18657526",42]
["Valproic Acid","Valproic Acid","D014635","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24968028","VPA alleviates neurological deficits and restores gene expression in a mouse model of Rett syndrome.","24968028",42]
["Verapamil","Verapamil","D014700","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2014,"24507022","Effect of verapamil and lidocaine on TRPM and NaV1.9 gene expressions in renal ischemia-reperfusion.","24507022",42]
["Vincristine","Vincristine","D014750","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2014,"24743146","Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain.","24743146",42]
["Vitamin A","Vitamin A","D014801","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2004,"15646024","Retinoic acid administration and vitamin A status modulate retinoid X receptor alpha and retinoic acid receptor alpha levels in mouse brown adipose tissue.","15646024",42]
["Vitamin A","Vitamin A","D014801","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1993,"8286591","Retinol differentially regulates male germ cell-associated kinase (mak) messenger ribonucleic acid expression during spermatogenesis.","8286591",42]
["Vitamin B 6","Vitamin B 6","D025101","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2005,"16273288","Vitamin B6 suppresses NF-kappaB activation in LPS-stimulated mouse macrophages.","16273288",42]
["Vitamin D","Vitamin D","D014807","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2003,"12894248","Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms.","12894248",42]
["Vitamin D","Vitamin D","D014807","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2007,"17223545","Perspectives on mechanisms of gene regulation by 1,25-dihydroxyvitamin D3 and its receptor.","17223545",42]
["Vitamin D","Vitamin D","D014807","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23436936","1,25-Dihydroxyvitamin D promotes negative feedback regulation of TLR signaling via targeting microRNA-155-SOCS1 in macrophages.","23436936",42]
["Vitamin D","Vitamin D","D014807","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2015,"25815722","Vitamin D prevents hypoxia/reoxygenation-induced blood-brain barrier disruption via vitamin D receptor-mediated NF-kB signaling pathways.","25815722",42]
["Vitamin D","Vitamin D","D014807","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"27742848","Vitamin D-binding protein as it is understood in 2016: is it a critical key with which to help to solve the calcitriol conundrum?","27742848",42]
["Vitamin D","Vitamin D","D014807","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1995,"7588303","Tissue-specific regulation by vitamin D status of nuclear and mitochondrial gene expression in kidney and intestine.","7588303",42]
["Vitamin E","Vitamin E","D014810","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23634235","Gamma-tocotrienol modulated gene expression in senescent human diploid fibroblasts as revealed by microarray analysis.","23634235",42]
["Vitamin K","Vitamin K","D014812","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2006,"16677080","Vitamin K epoxide reductase complex subunit 1 (VKORC1): the key protein of the vitamin K cycle.","16677080",42]
["Vitamin K 3","Vitamin K 3","D024483","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2016,"27167070","Menadione Suppresses Benzo(α)pyrene-Induced Activation of Cytochromes P450 1A: Insights into a Possible Molecular Mechanism.","27167070",42]
["vorinostat","vorinostat","C111237","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2017,"29073110","M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory.","29073110",42]
["Water","Water","D014867","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2013,"24223826","Non-genomic estrogen regulation of ion transport and airway surface liquid dynamics in cystic fibrosis bronchial epithelium.","24223826",42]
["Water","Water","D014867","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,1996,"8791336","Molecular responses to drought and cold stress.","8791336",42]
["withaferin A","withaferin A","C009684","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22117063","Corneal antifibrotic switch identified in genetic and pharmacological deficiency of vimentin.","22117063",42]
["Yellow Fever Vaccine","Yellow Fever Vaccine","D022341","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,1,2017,"28687661","A Systems Vaccinology Approach Reveals Temporal Transcriptomic Changes of Immune Responses to the Yellow Fever 17D Vaccine.","28687661",42]
["zearalenol","zearalenol","C029659","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22024015","Cytosol protein regulation in H295R steroidogenesis model induced by the zearalenone metabolites, α- and β-zearalenol.","22024015",42]
["Zeranol","Zeranol","D015029","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2012,"22024015","Cytosol protein regulation in H295R steroidogenesis model induced by the zearalenone metabolites, α- and β-zearalenol.","22024015",42]
["zinc chloride","zinc chloride","C016837","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,1987,"2827103","DNA repair in the metallothionein gene increases with transcriptional activation.","2827103",42]
["zoledronic acid","zoledronic acid","C088658","5_KE",756,5,"Hippocampal gene expression","Altered","Gene Expression Regulation","D005786","Gene Expression Regulation",1,2,2013,"23807419","Bisphosphonates modulate vital functions of human osteoblasts and affect their interactions with breast cancer cells.","23807419",42]
["(3,4-dihydroxyphenylamino)-2-imidazoline","(3,4-dihydroxyphenylamino)-2-imidazoline","C011775","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1982,"7134232","Time course of certain behavioral changes after hippocampal damage and their alteration by dopaminergic intervention into nucleus accumbens.","7134232",42]
["(R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo(4,3-c)quinoline","(R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo(4,3-c)quinoline","C573127","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"26254735","Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome.","26254735",42]
["1-(2-pyridinyl)piperazine","1-(2-pyridinyl)piperazine","C052140","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"17494642","6-Hydroxybuspirone is a major active metabolite of buspirone: assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in rats.","17494642",42]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1993,"7689287","Effects of selective inhibition of protein kinase C, cyclic AMP-dependent protein kinase, and Ca(2+)-calmodulin-dependent protein kinase on neurite development in cultured rat hippocampal neurons.","7689287",42]
["1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester","C070379","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1991,"1657301","Postsynaptic and presynaptic effects of the calcium chelator BAPTA on synaptic transmission in rat hippocampal dentate granule neurons.","1657301",42]
["1,3-dimethyl-8-cyclopentylxanthine","1,3-dimethyl-8-cyclopentylxanthine","C112774","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9607713","The effects of adenine dinucleotides on epileptiform activity in the CA3 region of rat hippocampal slices.","9607713",42]
["17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol","17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol","C002029","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15351506","Prenatal exposure of Long-Evans rats to 17alpha-ethinylestradiol modifies neither latent inhibition nor prepulse inhibition of the startle reflex but elicits minor deficits in exploratory behavior.","15351506",42]
["1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine","1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine","C079794","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16288930","The neurotoxin 2'-NH2-MPTP degenerates serotonin axons and evokes increases in hippocampal BDNF.","16288930",42]
["1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine","D015632","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"25560396","MPTP-induced changes in hippocampal synaptic plasticity and memory are prevented by memantine through the BDNF-TrkB pathway.","25560396",42]
["1-Naphthylamine","1-Naphthylamine","D015057","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1383885","Serotonin uptake inhibition: in vivo effect of sertraline in rats.","1383885",42]
["2,2',3,5',6-pentachlorobiphenyl","2,2',3,5',6-pentachlorobiphenyl","C032904","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2009,"19289137","Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substituted polychlorinated biphenyls in the hippocampal slice preparation.","19289137",42]
["2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine","2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine","D015647","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21538463","SKF83959 suppresses excitatory synaptic transmission in rat hippocampus via a dopamine receptor-independent mechanism.","21538463",42]
["2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline","2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline","C062865","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1382998","Competitive inhibition by NBQX of kainate/AMPA receptor currents and excitatory synaptic potentials: importance of 6-nitro substitution.","1382998",42]
["2,4-dinitrophenylhydrazine","2,4-dinitrophenylhydrazine","C004787","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1998,"9603784","Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine.","9603784",42]
["2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid","2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid","C100921","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"14680755","Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats.","14680755",42]
["2-hydroxysaclofen","2-hydroxysaclofen","C057491","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2004,"15163674","Contribution of Ih and GABAB to synaptically induced afterhyperpolarizations in CA1: a brake on the NMDA response.","15163674",42]
["2''-O-acetyl-polygalacin D2","2''-O-acetyl-polygalacin D2","C543853","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19433075","Platycodin D and 2''-O-acetyl-polygalacin D2 isolated from Platycodon grandiflorum protect ischemia/reperfusion injury in the gerbil hippocampus.","19433075",42]
["3-(2-(4-methyl-1-piperazinyl)-2-oxoethyl)-2-phenyl-3,5,6,7-tetrahydrocyclopenta(f)isoindol-1(2H)-one","3-(2-(4-methyl-1-piperazinyl)-2-oxoethyl)-2-phenyl-3,5,6,7-tetrahydrocyclopenta(f)isoindol-1(2H)-one","C534223","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"25451121","Neuroprotection by JM-1232(-) against oxygen-glucose deprivation-induced injury in rat hippocampal slice culture.","25451121",42]
["3,4-diaminopyridine","3,4-diaminopyridine","C016361","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1992,"1284575","[Modulation of 3,4-diaminopyridine-evoked norepinephrine release from rat hippocampal slices by activation of alpha 2-adrenoceptor].","1284575",42]
["3,4-Dihydroxyphenylacetic Acid","3,4-Dihydroxyphenylacetic Acid","D015102","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1990,"2251330","Environment-dependent effects of ethanol on DOPAC and HVA in various brain regions of ethanol-tolerant rats.","2251330",42]
["3,4-Methylenedioxyamphetamine","3,4-Methylenedioxyamphetamine","D015104","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1993,"8095837","Effects of L-type calcium channel antagonists on the serotonin-depleting actions of MDMA in rats.","8095837",42]
["3-butyl-1-phenyl-2-(phenyltelluro)oct-2-en-1-one","3-butyl-1-phenyl-2-(phenyltelluro)oct-2-en-1-one","C540925","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2010,"20668930","Effect of acute administration of 3-butyl-1-phenyl-2-(phenyltelluro)oct-en-1-one on oxidative stress in cerebral cortex, hippocampus, and cerebellum of rats.","20668930",42]
["3-n-butylphthalide","3-n-butylphthalide","C027125","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"25149651","Effects of L-3-n-butylphthalide on cognitive dysfunction and NR2B expression in hippocampus of streptozotocin (STZ)-induced diabetic rats.","25149651",42]
["3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester","3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester","D001498","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1990,"1696706","Pharmacological characterization of voltage-dependent calcium currents in rat hippocampal neurons.","1696706",42]
["4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine","4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine","C079549","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2000,"10727714","Roles of 5-HT(1A) receptors in the dorsal raphe and dorsal hippocampus in anxiety assessed by the behavioral effects of 8-OH-DPAT and S 15535 in a modified Geller-Seifter conflict model.","10727714",42]
["4-Aminopyridine","4-Aminopyridine","D015761","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2008,"18602900","Generalization of seizures parallels the formation of \"dark\" neurons in the hippocampus and pontine reticular formation after focal-cortical application of 4-aminopyridine (4-AP) in the rat.","18602900",42]
["4-Aminopyridine","4-Aminopyridine","D015761","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1986,"3012420","Depression of spike adaptation and afterhyperpolarization by 4-aminopyridine in hippocampal neurons.","3012420",42]
["4-Aminopyridine","4-Aminopyridine","D015761","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9356408","Ionic mechanisms of spontaneous GABAergic events in rat hippocampal slices exposed to 4-aminopyridine.","9356408",42]
["4-chloro-N-(5-nitro-2-thiazoyl)benezenesulfonamide","4-chloro-N-(5-nitro-2-thiazoyl)benezenesulfonamide","C098823","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"8787800","A new compound (AZ36041) promotes the survival of the neurons and reduces neurotoxicity of Alzheimer's beta-amyloid protein.","8787800",42]
["4-naphthalene-1-yl-3a,4,5,9b-tetrahydro-3-H-cyclopenta(c)quinoline-8-sulfonic acid amide","4-naphthalene-1-yl-3a,4,5,9b-tetrahydro-3-H-cyclopenta(c)quinoline-8-sulfonic acid amide","C523471","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27154173","Effects of alpha-7 nicotinic acetylcholine receptor positive allosteric modulator on lipopolysaccharide-induced neuroinflammatory pain in mice.","27154173",42]
["5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride","5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride","C466420","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"17292620","FeTPPS protects against global cerebral ischemic-reperfusion injury in gerbils.","17292620",42]
["5,7-Dihydroxytryptamine","5,7-Dihydroxytryptamine","D015116","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2008,"18845420","Serotonin depletion effects on the pilocarpine model of epilepsy.","18845420",42]
["5-iodo-3-(2-azetidinylmethoxy)pyridine","5-iodo-3-(2-azetidinylmethoxy)pyridine","C426745","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2008,"18582447","Stimulation of the alpha4beta2 nicotinic receptor by 5-I A-85380 improves auditory gating in DBA/2 mice.","18582447",42]
["6,7-dihydroxyflavone","6,7-dihydroxyflavone","C485383","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2012,"22194327","7,8-dihydroxyflavone exhibits therapeutic efficacy in a mouse model of Rett syndrome.","22194327",42]
["6-Cyano-7-nitroquinoxaline-2,3-dione","6-Cyano-7-nitroquinoxaline-2,3-dione","D018750","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1988,"2903471","Blockade of excitatory synaptic transmission by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) in the hippocampus in vitro.","2903471",42]
["6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid","6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid","C010643","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1989,"2593184","Free radicals mediate peroxidative damage in guinea pig hippocampus in vitro.","2593184",42]
["7-chloro-5-(2-isopropylphenyl)-3,5-dihydro-4,1-benzothiazepin-2-(1H)-one","7-chloro-5-(2-isopropylphenyl)-3,5-dihydro-4,1-benzothiazepin-2-(1H)-one","C000605974","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"26774037","Neuroprotective profile of pyridothiazepines with blocking activity of the mitochondrial Na(+)/Ca(2+) exchanger.","26774037",42]
["8,11,14-Eicosatrienoic Acid","8,11,14-Eicosatrienoic Acid","D015126","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"7909586","Formation and electrophysiological actions of the arachidonic acid metabolites, hepoxilins, at nanomolar concentrations in rat hippocampal slices.","7909586",42]
["8-Hydroxy-2-(di-n-propylamino)tetralin","8-Hydroxy-2-(di-n-propylamino)tetralin","D017371","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2000,"10991934","Low doses of 8-OH-DPAT prevent the impairment of spatial learning caused by intrahippocampal scopolamine through 5-HT(1A) receptors in the dorsal raphe.","10991934",42]
["8-Hydroxy-2-(di-n-propylamino)tetralin","8-Hydroxy-2-(di-n-propylamino)tetralin","D017371","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2010,"21028935","Evaluation of a combined therapeutic regimen of 8-OH-DPAT and environmental enrichment after experimental traumatic brain injury.","21028935",42]
["A 078","A 078","C065426","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1990,"2385362","Anticonvulsant effects of tetronic acid derivatives on picrotoxin induced epileptiform activity in rat hippocampal slices.","2385362",42]
["Acetaminophen","Acetaminophen","D000082","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19688255","Brain creatine kinase activity is inhibited after hepatic failure induced by carbon tetrachloride or acetaminophen.","19688255",42]
["Acetylcarnitine","Acetylcarnitine","D000108","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2007,"17610872","Acetyl-L-carnitine ameliorates hypobaric hypoxic impairment and spatial memory deficits in rats.","17610872",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10024347","Modulation of long-term synaptic depression in visual cortex by acetylcholine and norepinephrine.","10024347",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2000,"11040261","Increasing acetylcholine levels in the hippocampus or entorhinal cortex reverses the impairing effects of septal GABA receptor activation on spontaneous alternation.","11040261",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C54595,B54595)","v":"Acetylcholine"},"Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J54595,K54595)","v":"Hippocampus"},"D006624","Hippocampus",2,4,2002,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q54595,Q54595)","v":"12099905"},"5,7-DHT-induced hippocampal 5-HT depletion attenuates behavioural deficits produced by 192 IgG-saporin lesions of septal cholinergic neurons in the rat.","12099905",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2003,"12874603","Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice.","12874603",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"14747523","Cholinergic modulation of the hippocampus during encoding and retrieval of tone/shock-induced fear conditioning.","14747523",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1633277","BDNF and NGF treatment in lesioned rats: effects on cholinergic function and weight gain.","1633277",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2008,"17507114","The length of hippocampal cholinergic fibers is reduced in the aging brain.","17507114",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1991,"1833657","Effects of streptozotocin-induced diabetes on acetylcholine metabolism in rat brain.","1833657",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1990,"2156020","Differential sensitivity to blockade by 4-aminopyridine of presynaptic receptors regulating [3H]acetylcholine release from rat hippocampus.","2156020",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1975,"234276","Effects of dopaminergic receptor agonists and antagonists on the activity of the neo-striatal cholinergic system.","234276",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24704431","Altered acetylcholine release in the hippocampus of dystrophin-deficient mice.","24704431",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2017,"28791706","Cholinergic modulation of the hippocampal region and memory function.","28791706",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1979,"430073","Relationship between choline availability and acetylcholine synthesis in discrete regions of rat brain.","430073",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1972,"5028533","The use of microwave radiation in the determination of acetylcholine in the rat brain.","5028533",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1982,"6292779","Electrophysiological and pharmacological characteristics of facilitation of hippocampal population spikes by stimulation of the medial septum.","6292779",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7649496","Effect of systemic dexamethasone on extracellular amino acids, GABA and acetylcholine release in rat hippocampus using in vivo microdialysis.","7649496",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1993,"8104663","Functional activity of intrahippocampal septal grafts is regulated by catecholaminergic host afferents as studied by microdialysis of acetylcholine.","8104663",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1993,"8403375","Recovery of [3H]acetylcholine synthesis after AF64A-treatment in primary, neuron-enriched, rat septal-hippocampal and striatal cultures.","8403375",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1996,"8694460","Vestibular influences on the histaminergic and cholinergic systems in the rat brain.","8694460",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"8978740","Effect of pentylenetetrazole-induced kindling on acetylcholine release in the hippocampus of freely moving rats.","8978740",42]
["Acetylcholine","Acetylcholine","D000109","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9832381","GABA receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo.","9832381",42]
["Aconitine","Aconitine","D000157","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2002,"11895105","Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo.","11895105",42]
["Acyclovir","Acyclovir","D000212","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2005,"15969948","Aciclovir protects against quinolinic-acid-induced oxidative neurotoxicity.","15969948",42]
["agroclavine","agroclavine","C004465","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19559766","Agroclavine potentiates hippocampal EEG effects of weak combined magnetic field in rats.","19559766",42]
["allose","allose","C002055","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27342700","d-Allose Attenuates Overexpression of Inflammatory Cytokines after Cerebral Ischemia/Reperfusion Injury in Gerbil.","27342700",42]
["alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid","alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid","D018350","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1380390","Long-term potentiation is associated with increased [3H]AMPA binding in rat hippocampus.","1380390",42]
["alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid","alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid","D018350","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19603152","Chronic treatment with AMPA receptor potentiator Org 26576 increases neuronal cell proliferation and survival in adult rodent hippocampus.","19603152",42]
["alpha-methylhistamine","alpha-methylhistamine","C069357","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2000,"10800750","Effect of R-(-)-alpha-methylhistamine and thioperamide on in vivo release of norepinephrine in the rat hippocampus.","10800750",42]
["alpha-Tocopherol","alpha-Tocopherol","D024502","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27983697","α-Tocopherol and Hippocampal Neural Plasticity in Physiological and Pathological Conditions.","27983697",42]
["aluminum chloride","aluminum chloride","C010845","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2006,"16571282","Protective effect of Ginkgo biloba leaf extract on learning and memory deficit induced by aluminum in model rats.","16571282",42]
["aluminum lactate","aluminum lactate","C104223","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2007,"18681236","Chronic exposure to low levels of aluminum alters cerebral cell signaling in response to acute MPTP administration.","18681236",42]
["Aminooxyacetic Acid","Aminooxyacetic Acid","D000625","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1996,"8930249","Hyperexcitability of entorhinal cortex and hippocampus after application of aminooxyacetic acid (AOAA) to layer III of the rat medial entorhinal cortex in vitro.","8930249",42]
["Amitriptyline","Amitriptyline","D000639","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1986,"3708037","Stress-induced immobility in rats with cholinergic supersensitivity.","3708037",42]
["Ammonium Chloride","Ammonium Chloride","D000643","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1993,"7908597","Effects of ammonium ions on synaptic transmission and on responses to quisqualate and N-methyl-D-aspartate in hippocampal CA1 pyramidal neurons in vitro.","7908597",42]
["Amphetamine","Amphetamine","D000661","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2010,"20450937","Combined lesions of GABAergic and cholinergic septal neurons increase locomotor activity and potentiate the locomotor response to amphetamine.","20450937",42]
["Amphetamine","Amphetamine","D000661","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1969,"5783186","Effect of learning and of drugs on the ribonucleic acid concentration of brain structures of the rat.","5783186",42]
["Anabasine","Anabasine","D000691","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2008,"18321476","Modulation of spontaneous hippocampal synaptic events with 5-hydroxyindole, 4OH-GTS-21, and rAAV-mediated alpha7 nicotinic receptor gene transfer.","18321476",42]
["anandamide","anandamide","C078814","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2011,"21801815","Hippocampal endocannabinoids play an important role in induction of long-term potentiation and regulation of contextual fear memory formation.","21801815",42]
["anisyl alcohol","anisyl alcohol","C066943","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"26695827","Preventive Effect of 3,5-dihydroxy-4-methoxybenzyl Alcohol (DHMBA) and Zinc, Components of the Pacific Oyster Crassostrea gigas, on Glutamatergic Neuron Activity in the Hippocampus.","26695827",42]
["Antipyrine","Antipyrine","D000983","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19558813","[Effects of edaravone on IRE1 mRNA expression and neuronal apoptosis in the hippocampus of rats with status convulsivus].","19558813",42]
["Apigenin","Apigenin","D047310","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2017,"28237914","Apigenin attenuates hippocampal oxidative events, inflammation and pathological alterations in rats fed high fat, fructose diet.","28237914",42]
["Arachidonic Acid","Arachidonic Acid","D016718","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10323265","Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid metabolism in astrocytes.","10323265",42]
["Arachidonic Acid","Arachidonic Acid","D016718","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"8788426","Interactions between arachidonic acid and metabotropic glutamate receptors in the induction of synaptic potentiation in the rat hippocampal slice.","8788426",42]
["argiotoxin-636","argiotoxin-636","C558368","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1989,"2540876","Argiotoxin-636 blocks excitatory synaptic transmission in rat hippocampal CA1 pyramidal neurons.","2540876",42]
["asarone","asarone","C012195","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2016,"26271288","β-Asarone Mitigates Amyloidosis and Downregulates RAGE in a Transgenic Mouse Model of Alzheimer's Disease.","26271288",42]
["Ascorbic Acid","Ascorbic Acid","D001205","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2012,"22154133","Ascorbic acid treatment, similarly to fluoxetine, reverses depressive-like behavior and brain oxidative damage induced by chronic unpredictable stress.","22154133",42]
["Atorvastatin Calcium","Atorvastatin Calcium","D000069059","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2012,"22664571","Combination therapy of atorvastatin and amlodipine inhibits sympathetic nervous system activation and improves cognitive function in hypertensive rats.","22664571",42]
["Atropine","Atropine","D001285","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1964,"14181246","THE EFFECT OF NEOCORTICAL AND HIPPOCAMPAL SPREADING DEPRESSION ON THE SLOW WAVE EEG ACTIVITY INDUCED BY ATROPINE.","14181246",42]
["Atropine","Atropine","D001285","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1986,"3760938","Cholinergic septal grafts into the hippocampal formation improve spatial learning and memory in aged rats by an atropine-sensitive mechanism.","3760938",42]
["Baclofen","Baclofen","D001418","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2003,"12470702","Baclofen reestablishes striatal and cortical dopamine concentrations during naloxone-precipitated withdrawal.","12470702",42]
["Baclofen","Baclofen","D001418","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1989,"2562298","Modulation of striatal serotonin metabolism by baclofen, a gamma-aminobutyric acidB receptor agonist.","2562298",42]
["Baclofen","Baclofen","D001418","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7783835","Baclofen is cytoprotective to cerebral ischemia in gerbils.","7783835",42]
["baicalein","baicalein","C006680","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1993,"8272188","Involvement of phospholipase A2 and arachidonic acid in the depolarization-evoked accumulation of Ca2+ in hippocampal mossy fiber nerve endings.","8272188",42]
["Benzo(a)pyrene","Benzo(a)pyrene","D001564","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"24053913","[Effects of benzo(a)pyrene exposure on oxidative stress and ATPase in the hippocampus of rats].","24053913",42]
["Berberine","Berberine","D001599","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1999,"12532784","[Research on the mechanism of neuronal apoptosis in Alzheimer's disease and the effects of tetrohydroberberine on the apoptosis].","12532784",42]
["beta-carboline-3-carboxylic acid methyl ester","beta-carboline-3-carboxylic acid methyl ester","C036150","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1985,"2861248","Effects of two convulsant beta-carboline derivatives, DMCM and beta-CCM, on regional neurotransmitter amino acid levels and on in vitro D-[3H]aspartate release in rodents.","2861248",42]
["betulinic acid","betulinic acid","C002070","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"26287580","Ameliorative effect of betulin from Betula platyphylla bark on scopolamine-induced amnesic mice.","26287580",42]
["Bicuculline","Bicuculline","D001640","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1995,"7746512","Epileptic tolerance: prior seizures protect against seizure-induced neuronal injury.","7746512",42]
["bicuculline methochloride","bicuculline methochloride","C006749","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2001,"11755223","Modulation of synaptic transmission in hippocampal CA1 neurons by a novel neurotoxin (beta-pompilidotoxin) derived from wasp venom.","11755223",42]
["bilobalide","bilobalide","C073710","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2003,"13130392","Structure-activity studies with Ginkgo biloba extract constituents as receptor-gated chloride channel blockers and modulators.","13130392",42]
["bisphenol A","bisphenol A","C006780","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"17467901","Memory impairment associated with a dysfunction of the hippocampal cholinergic system induced by prenatal and neonatal exposures to bisphenol-A.","17467901",42]
["Blood Glucose","Blood Glucose","D001786","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2001,"11087960","Long term modulation of the HPA axis by the hippocampus. Behavioral, biochemical and immunological endpoints in rats exposed to chronic mild stress.","11087960",42]
["Blood Glucose","Blood Glucose","D001786","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1991,"1780392","Changes in glucose metabolism in dementia of the Alzheimer type compared with depression: a preliminary report.","1780392",42]
["Blood Glucose","Blood Glucose","D001786","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1981,"7272766","Metabolic mapping of functional activity in the olfactory projections of the rat: ontogenetic study.","7272766",42]
["bremazocine","bremazocine","C027248","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1981,"6265981","Involvement of mu-receptors in the opioid-induced generation of bursting discharges in hippocampal pyramidal cells.","6265981",42]
["Buspirone","Buspirone","D002065","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1986,"2421657","Neurochemical effects of buspirone in rat hippocampus: evidence for selective activation of 5HT neurons.","2421657",42]
["Butyric Acid","Butyric Acid","D020148","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"23567105","Sodium butyrate-induced histone acetylation strengthens the expression of cocaine-associated contextual memory.","23567105",42]
["caffeic acid","caffeic acid","C040048","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27261577","Caffeic acid attenuates oxidative stress, learning and memory deficit in intra-cerebroventricular streptozotocin induced experimental dementia in rats.","27261577",42]
["Caffeine","Caffeine","D002110","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1996,"8886298","Hippocampal neurons are damaged by caffeine-augmented electroshock seizures.","8886298",42]
["calmidazolium","calmidazolium","C031938","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1988,"3179724","Inhibitors of calmodulin and protein kinase C block different phases of hippocampal long-term potentiation.","3179724",42]
["Cannabidiol","Cannabidiol","D002185","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21050680","Diminished gray matter in the hippocampus of cannabis users: possible protective effects of cannabidiol.","21050680",42]
["Carbachol","Carbachol","D002217","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2003,"12763063","Involvement of cholinergic and gabaergic systems in the fragile X knockout mice.","12763063",42]
["Carbachol","Carbachol","D002217","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1970,"4192816","Influence of increased local cholinergic activity on discharge patterns of hippocampal foci.","4192816",42]
["Carbachol","Carbachol","D002217","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1993,"8104089","Bidirectional modulation of long-term potentiation by carbachol via M1 and M2 muscarinic receptors in guinea pig hippocampal mossy fiber-CA3 synapses.","8104089",42]
["Carbamazepine","Carbamazepine","D002220","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1490097","Calcium antagonistic effects of carbamazepine as a mechanism of action in neuropsychiatric disorders: studies in calcium dependent model epilepsies.","1490097",42]
["Carbaryl","Carbaryl","D012721","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"23418109","Subchronic neurotoxicity of chlorpyrifos, carbaryl, and their combination in rats.","23418109",42]
["Carbon Dioxide","Carbon Dioxide","D002245","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1969,"5772434","Homeostatic mechanisms in the hypothalamus.","5772434",42]
["Carbon Monoxide","Carbon Monoxide","D002248","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2006,"16787598","[Effect of carbon monoxide and nitric oxide on the apoptosis of hippocampal neurons in rats with febrile seizures].","16787598",42]
["Carbon Monoxide","Carbon Monoxide","D002248","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1967,"6075033","An electrophysiological study of histotoxic anoxia under normal and under hyperbaric oxygenation.","6075033",42]
["Catechin","Catechin","D002392","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19221718","Epigallocatechin-3-gallate induced primary cultures of rat hippocampal neurons death linked to calcium overload and oxidative stress.","19221718",42]
["CD 349","CD 349","C054179","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1991,"1816763","Effect of CD349, a new dihydropyridine derivative Ca2+ antagonist, on the voltage-dependent Ca2+ currents in isolated mammalian brain neurons.","1816763",42]
["CGP 37157","CGP 37157","C079032","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2012,"22860221","Benzothiazepine CGP37157 and its isosteric 2'-methyl analogue provide neuroprotection and block cell calcium entry.","22860221",42]
["chaihu-shugan-san","chaihu-shugan-san","C497000","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2011,"22097208","[Effects of chaihu shugan powder on the behavior and expressions of BDNF and TrkB in the hippocampus, amygdala, and the frontal lobe in rat model of depression].","22097208",42]
["Chlormethiazole","Chlormethiazole","D002719","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1991,"1797307","Neuroprotective activity of chlormethiazole following transient forebrain ischaemia in the gerbil.","1797307",42]
["Chloroquine","Chloroquine","D002738","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1996,"8776504","Correlations between ganglioside storage degree and physiological characteristics of neuronal systems--experimental chloroquine intoxication in miniature pig.","8776504",42]
["Chlorpromazine","Chlorpromazine","D002746","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1973,"4775865","The action of neuroleptics in rats with altered catecholamine metabolism. 3. The effect of chlorpromazine, haloperidol and thioridazine on the brain dopamine and serotonin contents in the rats pretreated with MAO inhibitors.","4775865",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2004,"14967470","Exploring detergent insolubility in bovine hippocampal membranes: a critical assessment of the requirement for cholesterol.","14967470",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2008,"18685105","Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation.","18685105",42]
["Cholesterol","Cholesterol","D002784","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2014,"24756765","Cholesterol metabolism changes under long-term dietary restrictions while the cholesterol homeostasis remains unaffected in the cortex and hippocampus of aging rats.","24756765",42]
["Cholesterol, Dietary","Cholesterol, Dietary","D002791","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"17539481","High dietary cholesterol facilitates classical conditioning of the rabbit's nictitating membrane response.","17539481",42]
["Choline","Choline","D002794","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2002,"12223379","Multisection proton MR spectroscopy for mesial temporal lobe epilepsy.","12223379",42]
["Choline","Choline","D002794","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1990,"2315352","Effects of caerulein and cholecystokinin-octapeptide on acetylcholine and choline contents in the brains of intact and vagotomized mice.","2315352",42]
["Choline","Choline","D002794","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"26865644","Prenatal Choline Supplementation Diminishes Early-Life Iron Deficiency-Induced Reprogramming of Molecular Networks Associated with Behavioral Abnormalities in the Adult Rat Hippocampus.","26865644",42]
["Choline","Choline","D002794","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1987,"3683599","Choline increases endogenous GABA release in rat hippocampus by a mechanism sensitive to hemicholinium-3.","3683599",42]
["Choline","Choline","D002794","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"7897396","AF64A-induced brain damage and its relation to dementia.","7897396",42]
["Choline","Choline","D002794","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1998,"9535948","Prenatal dietary choline supplementation decreases the threshold for induction of long-term potentiation in young adult rats.","9535948",42]
["CI 966","CI 966","C067012","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1990,"2276082","Systemic CI-966, a new gamma-aminobutyric acid uptake blocker, enhances gamma-aminobutyric acid action in CA1 pyramidal layer in situ.","2276082",42]
["Cisplatin","Cisplatin","D002945","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24594220","Low-doses of cisplatin injure hippocampal synapses: a mechanism for 'chemo' brain?","24594220",42]
["Citalopram","Citalopram","D015283","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1993,"8419553","Serotonin 5-HT1A autoreceptor blockade potentiates the ability of the 5-HT reuptake inhibitor citalopram to increase nerve terminal output of 5-HT in vivo: a microdialysis study.","8419553",42]
["Clioquinol","Clioquinol","D007464","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2008,"18840509","The hippocampal region of rats and mice after a single i.p. dose of clioquinol: loss of synaptic zinc, cell death and c-Fos induction.","18840509",42]
["Clonazepam","Clonazepam","D002998","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2014,"25431174","Diabetic encephalopathy-related depression: experimental evidence that insulin and clonazepam restore antioxidant status in rat brain.","25431174",42]
["Clozapine","Clozapine","D003024","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2002,"12062902","Disruption of prepulse inhibition of startle reflex in a neurodevelopmental model of schizophrenia: reversal by clozapine, olanzapine and risperidone but not by haloperidol.","12062902",42]
["Clozapine","Clozapine","D003024","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1983,"6864552","Chronic fluphenazine and clozapine elicit opposite changes in brain muscarinic receptor binding: implications for understanding tardive dyskinesia.","6864552",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2003,"12524142","Cocaine inhibits 5-HT3 receptor function in neurons from transgenic mice overexpressing the receptor.","12524142",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16386305","Cocaine-mediated enhancement of Tat toxicity in rat hippocampal cell cultures: the role of oxidative stress and D1 dopamine receptor.","16386305",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"26215918","Hippocampal cell fate regulation by chronic cocaine during periods of adolescent vulnerability: Consequences of cocaine exposure during adolescence on behavioral despair in adulthood.","26215918",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"7700512","The effect of chronic morphine and cocaine administration on the Gs and Go protein messenger RNA levels in the rat hippocampus.","7700512",42]
["Cocaine","Cocaine","D003042","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9742166","Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.","9742166",42]
["Colchicine","Colchicine","D003078","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1989,"2533099","Effects of colchicine treatment on the cholinergic septohippocampal system.","2533099",42]
["Colforsin","Colforsin","D005576","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1986,"2941565","Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes.","2941565",42]
["Conus magus toxin","Conus magus toxin","C053423","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1989,"2543080","Localization and mobility of omega-conotoxin-sensitive Ca2+ channels in hippocampal CA1 neurons.","2543080",42]
["CORT 108297","CORT 108297","C558517","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2016,"27459932","New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity.","27459932",42]
["crotamine","crotamine","C010563","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24813333","The intrahippocampal infusion of crotamine from Crotalus durissus terrificus venom enhances memory persistence in rats.","24813333",42]
["Curcumin","Curcumin","D003474","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2016,"26924447","Effects of rapamycin and curcumin treatment on the development of epilepsy after electrically induced status epilepticus in rats.","26924447",42]
["Cycloheximide","Cycloheximide","D003513","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2003,"12788213","Cycloheximide inhibits neurotoxic responses induced by kainic acid in mice.","12788213",42]
["Cyclophosphamide","Cyclophosphamide","D003520","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2010,"20109567","Cyclophosphamide impairs hippocampus-dependent learning and memory in adult mice: Possible involvement of hippocampal neurogenesis in chemotherapy-induced memory deficits.","20109567",42]
["cyclothiazide","cyclothiazide","C004639","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1998,"9848091","The diazoxide derivative 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-S,S-dioxide augments AMPA- and GABA-mediated synaptic responses in cultured hippocampal neurons.","9848091",42]
["Dantrolene","Dantrolene","D003620","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10471088","Neuroprotective effects of early vs. late administration of dantrolene in experimental status epilepticus.","10471088",42]
["decabromobiphenyl ether","decabromobiphenyl ether","C010902","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2017,"28104350","Neonatal exposure to BDE 209 impaired learning and memory, decreased expression of hippocampal core SNAREs and synaptophysin in adult rats.","28104350",42]
["Deferoxamine","Deferoxamine","D003676","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2003,"12560112","Deferoxamine, allopurinol and oxypurinol are not neuroprotective after oxygen/glucose deprivation in an organotypic hippocampal model, lacking functional endothelial cells.","12560112",42]
["Deoxyglucose","Deoxyglucose","D003847","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"17041593","2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure.","17041593",42]
["Deoxyglucose","Deoxyglucose","D003847","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1993,"8099434","A neuroprotective effect of histamine H1 receptor antagonist on ischemia-induced decrease in 2-deoxyglucose uptake in rat hippocampal slices.","8099434",42]
["Desipramine","Desipramine","D003891","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2007,"17634380","cAMP response element-binding protein deficiency allows for increased neurogenesis and a rapid onset of antidepressant response.","17634380",42]
["Desipramine","Desipramine","D003891","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1984,"6088257","Behavioral evidence for alpha 1-adrenoceptor up- and alpha 2-adrenoceptor down-regulation in the rat hippocampus after chronic desipramine treatment.","6088257",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2007,"17621647","Treatment with dexamethasone and vitamin D3 attenuates neuroinflammatory age-related changes in rat hippocampus.","17621647",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2013,"23398290","Retinoids and glucocorticoids target common genes in hippocampal HT22 cells.","23398290",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1988,"3171581","Effect of dexamethasone on transport of alpha-aminoisobutyric acid and sucrose across the blood-brain barrier.","3171581",42]
["Dexamethasone","Dexamethasone","D003907","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1996,"8756562","Differential regulation of the growth hormone receptor gene: effects of dexamethasone and estradiol.","8756562",42]
["Dextroamphetamine","Dextroamphetamine","D003913","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"23178911","Chronic D-amphetamine administered from childhood to adulthood dose-dependently increases the survival of new neurons in the hippocampus of male C57BL/6J mice.","23178911",42]
["Dextroamphetamine","Dextroamphetamine","D003913","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9759978","Brain regional substrates for the actions of the novel wake-promoting agent modafinil in the rat: comparison with amphetamine.","9759978",42]
["di-2-(ethylhexyl)phosphoric acid","di-2-(ethylhexyl)phosphoric acid","C007377","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21782900","Acute postnatal exposure to di(2-ethylhexyl) phthalate adversely impacts hippocampal development in the male rat.","21782900",42]
["Diazepam","Diazepam","D003975","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1992,"1594636","Raised [3H]-5-HT release and 45Ca2+ uptake in diazepam withdrawal: inhibition by baclofen.","1594636",42]
["Diazepam","Diazepam","D003975","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1968,"4967002","Effects of diazepam on secondary subcortical epileptogenic tissues.","4967002",42]
["Diazepam","Diazepam","D003975","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7823161","Diazepam, given postischemia, protects selectively vulnerable neurons in the rat hippocampus and striatum.","7823161",42]
["Diazinon","Diazinon","D003976","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24561003","Astrocytes protect against diazinon- and diazoxon-induced inhibition of neurite outgrowth by regulating neuronal glutathione.","24561003",42]
["Dibutyl Phthalate","Dibutyl Phthalate","D003993","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"23736097","Neurotoxicity of dibutyl phthalate in brain development following perinatal exposure: a study in rats.","23736097",42]
["dihydrokainic acid","dihydrokainic acid","C020889","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1997,"9282938","Glutamate uptake impairment and neuronal damage in young and aged rats in vivo.","9282938",42]
["dihydroxyphenylethylene glycol","dihydroxyphenylethylene glycol","C010117","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15518642","Antisense oligonucleotide against GTPase Rab5b inhibits metabotropic agonist DHPG-induced neuroprotection.","15518642",42]
["Dimethyl Sulfoxide","Dimethyl Sulfoxide","D004121","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1976,"1088567","Action of ethanol and other solvents on the nerve tissue under in vitro conditions.","1088567",42]
["diphenyldiselenide","diphenyldiselenide","C061132","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"25841878","Antinociceptive action of diphenyl diselenide in the nociception induced by neonatal administration of monosodium glutamate in rats.","25841878",42]
["Dithizone","Dithizone","D004230","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1989,"2475471","Evidence from dithizone and selenium zinc histochemistry that perivascular mossy fiber boutons stain preferentially \"in vivo\".","2475471",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2002,"11999902","Effects of MK-801 and electroconvulsive shock on c-Fos expression in the rat hippocampus and frontal cortex.","11999902",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1992,"1407718","Regional effects of MK-801 on dopamine and its metabolites studied by in vivo microdialysis.","1407718",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1990,"2175367","The role of NMDA receptors in epilepsy: II. Effects of NMDA receptor antagonists (CPP and MK-801) on hippocampal long-term potentiation in anesthetized rats.","2175367",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2016,"26518518","Soaping the NMDA receptor: Various types of detergents influence differently [(3)H]MK-801 binding to rat brain membranes.","26518518",42]
["Dizocilpine Maleate","Dizocilpine Maleate","D016291","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7667365","[3H]MK-801 binding to well-washed rat brain membranes following cessation of chronic phencyclidine treatment.","7667365",42]
["docosapentaenoic acid","docosapentaenoic acid","C026219","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2005,"15718358","Brain docosahexaenoic acid status and learning in young rats submitted to dietary long-chain polyunsaturated fatty acid deficiency and supplementation limited to lactation.","15718358",42]
["domoic acid","domoic acid","C012301","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2012,"22366222","Enhanced neurogenesis in organotypic cultures of rat hippocampus after transient subfield-selective excitotoxic insult induced by domoic acid.","22366222",42]
["donepezil","donepezil","C076946","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15158174","Comparison of the effect of TAK-147 (zanapezil) and E-2020 (donepezil) on extracellular acetylcholine level and blood flow in the ventral hippocampus of freely moving rats.","15158174",42]
["donepezil","donepezil","C076946","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21704049","Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats.","21704049",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2000,"11069974","Neuroprotective role of dopamine against hippocampal cell death.","11069974",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1999,"11270989","Inhibitory effect of dopamine on Ca(2+)-calmodulin-dependent protein kinase II activity in rat hippocampal slices.","11270989",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1992,"1307673","[Cerebral ischemia: massive increase of the dopamine release or stagnation?].","1307673",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15081388","Dimemorfan enhances acetylcholine release from rat hippocampal slices.","15081388",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16876207","Effects of dorsal and ventral hippocampal NMDA stimulation on nucleus accumbens core and shell dopamine release.","16876207",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2008,"17767807","Pergolide protects CA1 neurons from apoptosis in a gerbil model of global cerebral ischemia.","17767807",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2008,"18815264","Critical role of the prefrontal cortex in the regulation of hippocampus-accumbens information flow.","18815264",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2011,"21411669","Aversive stimuli alter ventral tegmental area dopamine neuron activity via a common action in the ventral hippocampus.","21411669",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2012,"22760093","Effects of perinatal exposure to low dose of bisphenol A on anxiety like behavior and dopamine metabolites in brain.","22760093",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"23911670","Involvement of the dopaminergic and serotonergic systems in the antidepressant-like effect caused by 4-phenyl-1-(phenylselanylmethyl)-1,2,3-triazole.","23911670",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27966748","Effect of selective serotonin reuptake inhibitors on expression of 5-HT1AR and neurotransmitters in rats with vascular dementia.","27966748",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2017,"27817108","Effects of Neonatal Methamphetamine and Stress on Brain Monoamines and Corticosterone in Preweanling Rats.","27817108",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1985,"3995281","Catecholamine topochemistry in human basal ganglia. Comparison between normal and Alzheimer brains.","3995281",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1984,"6091884","Modulation by dopamine of population spikes in area CA1 hippocampal neurons elicited by paired stimulus pulses.","6091884",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1984,"6726660","Microiontophoretic studies of the dopaminergic inhibition from the ventral tegmental area to the nucleus accumbens neurons.","6726660",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1996,"8737446","Dopamine-induced ionic currents in acutely dissociated rat neurons of CNS.","8737446",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9253008","Perinatal methadone exposure affects dopamine, norepinephrine, and serotonin in the weanling rat.","9253008",42]
["Dopamine","Dopamine","D004298","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1998,"9763469","Induction of NF-kappaB activity during haloperidol-induced oxidative toxicity in clonal hippocampal cells: suppression of NF-kappaB and neuroprotection by antioxidants.","9763469",42]
["Dronabinol","Dronabinol","D013759","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15255998","Prolonged cannabinoid treatment results in spatial working memory deficits and impaired long-term potentiation in the CA1 region of the hippocampus in vivo.","15255998",42]
["Dronabinol","Dronabinol","D013759","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1999,"9882692","Delta9-tetrahydrocannabinol acts as a partial agonist to modulate glutamatergic synaptic transmission between rat hippocampal neurons in culture.","9882692",42]
["DSP 4","DSP 4","C012102","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1982,"6812102","DSP4-induced two-way active avoidance impairment in rats: involvement of central and not peripheral noradrenaline depletion.","6812102",42]
["Egtazic Acid","Egtazic Acid","D004533","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2000,"10924670","Involvement of calmodulin-dependent protein kinase II in carbachol-induced rhythmic activity in the hippocampus of the rat.","10924670",42]
["eldeline","eldeline","C119644","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10225364","Frequency- and structure-dependent inhibition of normal and epileptiform activity by 6-benzoyldeltamine in rat hippocampal slices.","10225364",42]
["endotoxin, Escherichia coli","endotoxin, Escherichia coli","C044101","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"26223783","Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice.","26223783",42]
["epigallocatechin gallate","epigallocatechin gallate","C045651","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2001,"11811904","The green tea polyphenol (-)-epigallocatechin gallate attenuates beta-amyloid-induced neurotoxicity in cultured hippocampal neurons.","11811904",42]
["epigallocatechin gallate","epigallocatechin gallate","C045651","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2015,"25474041","Enhancement of flavonoid ability to cross the blood-brain barrier of rats by co-administration with α-tocopherol.","25474041",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1999,"10213167","Vitamin E and beta-carotene protect against ethanol combined with ischemia in an embryonic rat hippocampal culture model of fetal alcohol syndrome.","10213167",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2000,"11106855","Ethanol neurobehavioral teratogenesis and the role of the hippocampal glutamate-N-methyl-D-aspartate receptor-nitric oxide synthase system.","11106855",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2002,"12023522","Ifenprodil and ethanol enhance NMDA receptor-dependent long-term depression.","12023522",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2003,"12774854","Chronic prenatal ethanol exposure-induced decrease of guinea pig hippocampal CA1 pyramidal cell and cerebellar Purkinje cell density.","12774854",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15608609","Cytotoxic effects of exposure to the human immunodeficiency virus type 1 protein Tat in the hippocampus are enhanced by prior ethanol treatment.","15608609",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1617441","Chronic ethanol treatment reduces inhibition in CA1 of the rat hippocampus.","1617441",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1991,"1711814","Sensitivity of N-methyl-D-aspartate (NMDA) and nicotinic acetylcholine receptors to ethanol and pyrazole.","1711814",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"18034701","Formic acid, a novel metabolite of chronic ethanol abuse, causes neurotoxicity, which is prevented by folic acid.","18034701",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1991,"2058888","Differential effects of pentobarbital and ethanol on the carbachol-induced rhythmical activity of the in vitro hippocampal formation.","2058888",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21352243","Effects of dose and period of neonatal alcohol exposure on the context preexposure facilitation effect.","21352243",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2012,"22790976","Attenuation of oxidative stress, neuroinflammation, and apoptosis by curcumin prevents cognitive deficits in rats postnatally exposed to ethanol.","22790976",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"24040071","Fate analysis of adult hippocampal progenitors in a murine model of fetal alcohol spectrum disorder (FASD).","24040071",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2016,"26264240","Chronic Alcohol Exposure Decreases 53BP1 Protein Levels Leading to a Defective DNA Repair in Cultured Primary Cortical Neurons.","26264240",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27213757","Changes in the Adult GluN2B Associated Proteome following Adolescent Intermittent Ethanol Exposure.","27213757",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2017,"28723918","Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder.","28723918",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1984,"6141955","[Interhemispheric relation of brain structures in various functional states of the central nervous system].","6141955",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1995,"7528263","Allosteric regulation of the N-methyl-D-aspartate receptor-linked ion channel complex and effects of ethanol in ethanol-withdrawal seizure-prone and -resistant mice.","7528263",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1995,"7770006","Chronic ethanol treatment differentially regulates NMDA receptor subunit mRNA expression in rat brain.","7770006",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1993,"8333597","Ethanol-induced suppression of hippocampal long-term potentiation is blocked by lesions of the septohippocampal nucleus.","8333597",42]
["Ethanol","Ethanol","D000431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1998,"9514286","Optical monitoring of living brain tissue.","9514286",42]
["Ether","Ether","D004986","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1999,"10529444","Differential forebrain c-fos mRNA induction by ether inhalation and novelty: evidence for distinctive stress pathways.","10529444",42]
["ethylcholine aziridinium","ethylcholine aziridinium","C044894","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15223371","Glycosaminoglycan C3 protects against AF64A-induced cholinotoxicity in a dose-dependent and time-dependent manner.","15223371",42]
["Ethylene Chlorohydrin","Ethylene Chlorohydrin","D005023","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9720786","Inhibition of excitatory amino acid-activated currents by trichloroethanol and trifluoroethanol in mouse hippocampal neurones.","9720786",42]
["etiracetam","etiracetam","C026098","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2003,"12941379","Reduction of voltage-operated potassium currents by levetiracetam: a novel antiepileptic mechanism of action?","12941379",42]
["etiracetam","etiracetam","C026098","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"24098559","Additional antiepileptic mechanisms of levetiracetam in lithium-pilocarpine treated rats.","24098559",42]
["Eugenol","Eugenol","D005054","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"24024340","Effects of combined acupuncture and eugenol on learning-memory ability and antioxidation system of hippocampus in Alzheimer disease rats via olfactory system stimulation.","24024340",42]
["Fenfluramine","Fenfluramine","D005277","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1991,"1710793","Differential effects of d-fenfluramine and p-chloroamphetamine on H75/12-induced depletion of 5-hydroxytryptamine and dopamine in the rat brain.","1710793",42]
["fenvalerate","fenvalerate","C017690","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2017,"28007640","The insecticide esfenvalerate modulates neuronal excitability in mammalian central nervous system in vitro.","28007640",42]
["ferulic acid","ferulic acid","C004999","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2013,"23401261","Ferulic acid prevents cerebral ischemic injury-induced reduction of hippocalcin expression.","23401261",42]
["Finasteride","Finasteride","D018120","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24861264","Neonatal allopregnanolone or finasteride administration modifies hippocampal K(+) Cl(-) co-transporter expression during early development in male rats.","24861264",42]
["Flumazenil","Flumazenil","D005442","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1994,"7884817","Astroglia-released factor shows similar effects as benzodiazepine inverse agonists.","7884817",42]
["Flunitrazepam","Flunitrazepam","D005445","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2008,"17976880","Antipsychotic drug administration differentially affects [3H]muscimol and [3H]flunitrazepam GABA(A) receptor binding sites.","17976880",42]
["Fluorodeoxyglucose F18","Fluorodeoxyglucose F18","D019788","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1999,"10599778","Glucose and [11C]flumazenil positron emission tomography abnormalities of thalamic nuclei in temporal lobe epilepsy.","10599778",42]
["fluoropalonosetron","fluoropalonosetron","C000620653","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2016,"27571447","Synthesis and Pharmacological Evaluation of [11C]Granisetron and [18F]Fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging.","27571447",42]
["Fluoxetine","Fluoxetine","D005473","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19110032","Effects of fluoxetine on the rat brain in the forced swimming test: a [F-18]FDG micro-PET imaging study.","19110032",42]
["Fluoxetine","Fluoxetine","D005473","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21537331","Antidepressants recruit new neurons to improve stress response regulation.","21537331",42]
["Fluoxetine","Fluoxetine","D005473","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"23876404","Quetiapine add-on therapy improves the depressive behaviors and hippocampal neurogenesis in fluoxetine treatment resistant depressive rats.","23876404",42]
["Fluoxetine","Fluoxetine","D005473","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"26679264","Fluoxetine normalizes disrupted light-induced entrainment, fragmented ultradian rhythms and altered hippocampal clock gene expression in an animal model of high trait anxiety- and depression-related behavior.","26679264",42]
["Flurbiprofen","Flurbiprofen","D005480","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2005,"15850676","Transgenic AD model mice, effects of potential anti-AD treatments on inflammation and pathology.","15850676",42]
["FM1 43","FM1 43","C073804","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2005,"15767463","Two modes of exocytosis at hippocampal synapses revealed by rate of FM1-43 efflux from individual vesicles.","15767463",42]
["Formaldehyde","Formaldehyde","D005557","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2001,"11301206","Selective destruction of medial septal cholinergic neurons attenuates pyramidal cell suppression, but not excitation in dorsal hippocampus field CA1 induced by subcutaneous injection of formalin.","11301206",42]
["Fructose","Fructose","D005632","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19148780","The effects of topiramate on caspase-3 expression in hippocampus of basolateral amygdala (BLA) electrical kindled epilepsy rat.","19148780",42]
["fructose-1,6-diphosphate","fructose-1,6-diphosphate","C029063","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2008,"18433547","[Protective effect of fructose-1,6-diphosphate against ultrastructural damage in the hippocampus of rats with repeated febrile seizures].","18433547",42]
["Fucose","Fucose","D005643","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1993,"8377940","A role for the neural cell adhesion molecule in a late, consolidating phase of glycoprotein synthesis six hours following passive avoidance training of the young chick.","8377940",42]
["Furosemide","Furosemide","D005665","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1994,"7696591","Cl- transporter block enhances GABAergic spontaneous activity in rat hippocampal CA3 cells.","7696591",42]
["G(M1) Ganglioside","G(M1) Ganglioside","D005677","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1988,"3407451","Partial lesion of dorsal hippocampal afferents and GM1-ganglioside treatment effects on the two-way avoidance in rats.","3407451",42]
["Galactose","Galactose","D005690","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1991,"2054616","The amnesic substance 2-deoxy-D-galactose suppresses the maintenance of hippocampal LTP.","2054616",42]
["Galantamine","Galantamine","D005702","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16298243","Inhibition of hippocampal function in mild cognitive impairment: targeting the cholinergic hypothesis.","16298243",42]
["Gallamine Triethiodide","Gallamine Triethiodide","D005703","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1970,"5434822","Avoidance training of hippocampal theta waves in flaxedilized dogs and its relation to skeletal movement.","5434822",42]
["Genistein","Genistein","D019833","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2003,"14627498","Inhibitory effect of genistein on activation of STAT3 induced by brain ischemia/reperfusion in rat hippocampus.","14627498",42]
["Ginkgo biloba extract","Ginkgo biloba extract","C063170","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15212849","Age-related effects of Ginkgo biloba extract on synaptic plasticity and excitability.","15212849",42]
["Ginkgo biloba extract 50","Ginkgo biloba extract 50","C583942","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2014,"25137850","[Ginkgo biloba extract 50 inhibited beta-amyloid-induced oxidative stress in rats' hippocampal neurons: an experimental study].","25137850",42]
["ginsenoside Rh2","ginsenoside Rh2","C055305","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"23957360","Ginsenoside Rh2 improves learning and memory in mice.","23957360",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2000,"11201184","[Exogenous lactate sustains synaptic activity and neuronal viability, but fails to induce long-term potentiation (LTP)].","11201184",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2002,"12193220","Evidence that brain glucose availability influences exercise-enhanced extracellular 5-HT level in hippocampus: a microdialysis study in exercising rats.","12193220",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2004,"15509754","Glutamate mediates acute glucose transport inhibition in hippocampal neurons.","15509754",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1991,"1651372","Osmotic effects on the CA1 neuronal population in hippocampal slices with special reference to glucose.","1651372",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2010,"20944422","Amelioration of oxygen and glucose deprivation-induced neuronal death by chloroform fraction of bay leaves (Laurus nobilis).","20944422",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2012,"22932185","Effect of anterior nucleus of thalamus stimulation on glucose metabolism in hippocampus of epileptic rats.","22932185",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2014,"24513087","GABA(A) receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia.","24513087",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1988,"3185425","Metabolic alterations in fiber layers of the CA 1 region of the gerbil hippocampus following short-term ischemia: high-energy phosphates, glucose-related metabolites, and amino acids.","3185425",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1981,"7219882","Depression of cerebral glucose utilization during animal hypnosis in the rabbit.","7219882",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1994,"8082628","Ictal patterns of cerebral glucose utilization in children with epilepsy.","8082628",42]
["Glucose","Glucose","D005947","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1997,"9329348","Cortisol reduces hippocampal glucose metabolism in normal elderly, but not in Alzheimer's disease.","9329348",42]
["glyceryl 2-arachidonate","glyceryl 2-arachidonate","C094503","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19767452","Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons.","19767452",42]
["glyceryl 2-arachidonate","glyceryl 2-arachidonate","C094503","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24494683","Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state.","24494683",42]
["GQ1 ganglioside","GQ1 ganglioside","C060676","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2002,"12070076","Effects of the mono- and tetrasialogangliosides GM1 and GQ1b on ATP-induced long-term potentiation in hippocampal CA1 neurons.","12070076",42]
["Haloperidol","Haloperidol","D006220","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2001,"11490180","Chronic treatment with clozapine, but not haloperidol, increases striatal ecto-5'-nucleotidase activity in rats.","11490180",42]
["Haloperidol","Haloperidol","D006220","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"20939054","Schizophrenia and the nitric oxide controversy: do all things fall into place now?","20939054",42]
["Haloperidol","Haloperidol","D006220","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1984,"6588395","3H-imipramine binding sites in brain down-regulated by chronic nortriptyline and haloperidol but not mianserin treatment.","6588395",42]
["Haloperidol","Haloperidol","D006220","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9376455","Recent and remote memory dissociation: medication effects and hippocampal function in schizophrenia.","9376455",42]
["Hemicholinium 3","Hemicholinium 3","D006426","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1989,"2598029","Hemicholinium-3 prevents the working memory impairments and the cholinergic hypofunction induced by ethylcholine aziridinium ion (AF64A).","2598029",42]
["Heparin, Low-Molecular-Weight","Heparin, Low-Molecular-Weight","D006495","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"26464629","Low molecular weight heparin prevents lipopolysaccharide induced-hippocampus-dependent cognitive impairments in mice.","26464629",42]
["Heroin","Heroin","D003932","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"18977583","Hippocampal involvement due to heroin inhalation--\"chasing the dragon\".","18977583",42]
["Hexobarbital","Hexobarbital","D006591","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1977,"852555","[Comparative reactivity of the neo-, paleo- and archicortex of the brain under conditions of ether and hexanal anesthesia].","852555",42]
["Histamine","Histamine","D006632","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"25941083","In the brain of mice, 3-iodothyronamine (T1AM) is converted into 3-iodothyroacetic acid (TA1) and it is included within the signaling network connecting thyroid hormone metabolites with histamine.","25941083",42]
["Histamine","Histamine","D006632","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"7529327","Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy.","7529327",42]
["Histamine","Histamine","D006632","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9550293","H2 receptor-mediated facilitation and H3 receptor-mediated inhibition of noradrenaline release in the guinea-pig brain.","9550293",42]
["huperzine A","huperzine A","C050426","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10580706","Suppressive action produced by beta-amyloid peptide fragment 31-35 on long-term potentiation in rat hippocampus is N-methyl-D-aspartate receptor-independent: it's offset by (-)huperzine A.","10580706",42]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2012,"22499337","Facilitative functionalization of cyanine dye by an on-off-on fluorescent switch for imaging of H2O2 oxidative stress and thiols reducing repair in cells and tissues.","22499337",42]
["Hydrogen Sulfide","Hydrogen Sulfide","D006862","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2005,"15629133","Hydrogen sulfide may improve the hippocampal damage induced by recurrent febrile seizures in rats.","15629133",42]
["Hydrogen Sulfide","Hydrogen Sulfide","D006862","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1996,"8558235","The possible role of hydrogen sulfide as an endogenous neuromodulator.","8558235",42]
["Hydroxyindoleacetic Acid","Hydroxyindoleacetic Acid","D006897","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1969,"5345992","Stimulation of various forebrain structures and brain 5HT, 5HIAA and behaviour in rats.","5345992",42]
["Ibotenic Acid","Ibotenic Acid","D007051","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2002,"12148941","Ibotenic acid lesions of the medial septum retard delay eyeblink conditioning in rabbits (Oryctolagus cuniculus).","12148941",42]
["Ibotenic Acid","Ibotenic Acid","D007051","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1989,"2477650","On the use of ibotenic acid to lesion selectively different components of the hippocampal formation.","2477650",42]
["Ibotenic Acid","Ibotenic Acid","D007051","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1994,"7696571","Effects of bromohomoibotenate on metabotropic glutamate receptors.","7696571",42]
["iduronate 2-sulfate","iduronate 2-sulfate","C067448","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2005,"15849184","A functional dermatan sulfate epitope containing iduronate(2-O-sulfate)alpha1-3GalNAc(6-O-sulfate) disaccharide in the mouse brain: demonstration using a novel monoclonal antibody raised against dermatan sulfate of ascidian Ascidia nigra.","15849184",42]
["Imatinib Mesylate","Imatinib Mesylate","D000068877","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27320209","Imatinib methanesulfonate reduces hyperphosphorylation of tau following repeated peripheral exposure to lipopolysaccharide.","27320209",42]
["Imipramine","Imipramine","D007099","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1359445","The effects of electroconvulsive shock or imipramine on subtypes of alpha 1-adrenoceptors in the frontal cortex of the rat.","1359445",42]
["Imipramine","Imipramine","D007099","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2012,"22590738","[Correction of age-related changes in sphingolipid content in rat tissues by acid sphingomyelinase inhibition].","22590738",42]
["indicaxanthin","indicaxanthin","C469628","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"26227670","Indicaxanthin from Opuntia ficus-indica Crosses the Blood-Brain Barrier and Modulates Neuronal Bioelectric Activity in Rat Hippocampus at Dietary-Consistent Amounts.","26227670",42]
["Indomethacin","Indomethacin","D007213","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"26438564","Indomethacin induced gene regulation in the rat hippocampus.","26438564",42]
["Inositol","Inositol","D007294","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1969,"5370028","Gas chromatographic analysis of myo-inositol in microgram samples of brain.","5370028",42]
["Iohexol","Iohexol","D007472","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1982,"7134441","Neurotoxicity of iohexol: a new nonionic contrast medium.","7134441",42]
["ipsapirone","ipsapirone","C043077","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7613104","Effects of the serotonin-1A agonists buspirone and ipsapirone on field potentials in the hippocampus slice: comparison with carbamzepine and verapamil.","7613104",42]
["isodomoic acid A","isodomoic acid A","C524833","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"17640694","Isodomoic acids A and C exhibit low KA receptor affinity and reduced in vitro potency relative to domoic acid in region CA1 of rat hippocampus.","17640694",42]
["Isoflurane","Isoflurane","D007530","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2008,"19058511","Effects of isoflurane on hippocampal seizures at immature rats in vivo.","19058511",42]
["Isoflurane","Isoflurane","D007530","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27337223","α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons.","27337223",42]
["Isoflurane","Isoflurane","D007530","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9239594","The effect of isoflurane on biochemical changes during and electrophysiological recovery after anoxia in rat hippocampal slices.","9239594",42]
["Isoproterenol","Isoproterenol","D007545","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1991,"1724070","Acute effects of tetrahydroaminoacridine on beta-adrenoceptor-linked cyclic AMP accumulation in brain of young and middle-aged rats.","1724070",42]
["Ivermectin","Ivermectin","D007559","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1982,"6123439","Properties of benzodiazepine receptors in rat retina.","6123439",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10528118","Cyclooxygenase-2 selective inhibitors aggravate kainic acid induced seizure and neuronal cell death in the hippocampus.","10528118",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2001,"11166519","Acute cocaine-induced seizures: differential sensitivity of six inbred mouse strains.","11166519",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2002,"11889920","Comparative study of the epileptogenic effect of kainic acid injected into the cerebral cortex, hippocampus and amygdala in adult cats chronically implanted.","11889920",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2003,"12639970","The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death.","12639970",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1539071","Parenteral domoic acid impairs spatial learning in mice.","1539071",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2005,"16239280","Effects of focal injection of kainic acid into the mouse hippocampus in vitro and ex vivo.","16239280",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2006,"16825952","Lovastatin modulates increased cholesterol and oxysterol levels and has a neuroprotective effect on rat hippocampal neurons after kainate injury.","16825952",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2007,"18038624","[Effect of intrahippocampal kainic acid on the behavior of rats and functional state of mitochondria in brain structures].","18038624",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2010,"20214503","Potential neuroprotective effect of gamma-glutamylcysteine ethyl ester on rat brain against kainic acid-induced excitotoxicity.","20214503",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24520409","Acacetin inhibits glutamate release and prevents kainic acid-induced neurotoxicity in rats.","24520409",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2012,"22690801","Simultaneous BOLD fMRI and local field potential measurements during kainic acid-induced seizures.","22690801",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2016,"27064042","Stimulation of Anterior Thalamic Nuclei Protects Against Seizures and Neuronal Apoptosis in Hippocampal CA3 Region of Kainic Acid-induced Epileptic Rats.","27064042",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1988,"2902907","Changes in the activity of gamma-glutamyl transpeptidase induced by kainic acid and surgical lesions of the hippocampal formation in young rats.","2902907",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1988,"3191887","Behavioral effects of kainic acid administration on the immature brain.","3191887",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1979,"530529","Tremor: role of striatal cholinergic neurons and the effect of intrastriatal kainic acid.","530529",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1981,"7446279","Epilepsy: changes in local glucose consumption and brain pathology produced by kainic acid.","7446279",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1993,"7687961","Microglial and astrocytic cell responses in the rat hippocampus after an intracerebroventricular kainic acid injection.","7687961",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"8190362","Induction of c-fos mRNA expression in an in vitro hippocampal slice model of adult rats after kainate but not gamma-aminobutyric acid or bicuculline treatment.","8190362",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1996,"8985700","Glutamate AMPA receptors in the fascia dentata of human and kainate rat hippocampal epilepsy.","8985700",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9350506","Distribution of amyloid beta-protein immunoreactivity in the hippocampus of rats injected with kainate.","9350506",42]
["Kainic Acid","Kainic Acid","D007608","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9692722","An immunosuppressant, FK506, protects against neuronal dysfunction and death but has no effect on electrographic and behavioral activities induced by systemic kainate.","9692722",42]
["Kai-Xin-San","Kai-Xin-San","C000605449","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"24184266","A representative prescription for emotional disease, Ding-Zhi-Xiao-Wan restores 5-HT system deficit through interfering the synthesis and transshipment in chronic mild stress-induced depressive rats.","24184266",42]
["Ketamine","Ketamine","D007649","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21788311","The toxic effects of s(+)-ketamine on differentiating neurons in vitro as a consequence of suppressed neuronal Ca2+ oscillations.","21788311",42]
["Ketamine","Ketamine","D007649","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"25123439","Docosahexaenoic acid intake ameliorates ketamine-induced impairment of spatial cognition and learning ability in ICR mice.","25123439",42]
["Ketamine","Ketamine","D007649","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27488193","Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression.","27488193",42]
["Ketamine","Ketamine","D007649","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2017,"28415680","Long-term neurocognitive dysfunction in offspring via NGF/ ERK/CREB signaling pathway caused by ketamine exposure during the second trimester of pregnancy in rats.","28415680",42]
["KN 62","KN 62","C063302","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1995,"7798912","Persistent enhancement of sustained calcium-dependent glutamate release by phorbol esters: role of calmodulin-independent serine/threonine phosphorylation and actin disassembly.","7798912",42]
["Kynurenic Acid","Kynurenic Acid","D007736","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1992,"1334240","A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo.","1334240",42]
["Kynurenic Acid","Kynurenic Acid","D007736","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2015,"25074636","Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder.","25074636",42]
["Kynurenic Acid","Kynurenic Acid","D007736","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"8013546","Intrahippocampal administration of a glycine site antagonist impairs working memory performance of rats.","8013546",42]
["Lactic Acid","Lactic Acid","D019344","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1988,"3375817","Lactate-supported synaptic function in the rat hippocampal slice preparation.","3375817",42]
["lamotrigine","lamotrigine","C047781","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2005,"15660242","Effects of combined lamotrigine and valproate on basal and stimulated extracellular amino acids and monoamines in the hippocampus of freely moving rats.","15660242",42]
["Lasalocid","Lasalocid","D007832","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9413576","Nerve cell death induced by Ca2+ ionophores in dissociated hippocampal cultures. Protective action of the NMDA antagonist MK-801.","9413576",42]
["lead acetate","lead acetate","C008261","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"23146751","Perinatal exposure to lead induces morphological, ultrastructural and molecular alterations in the hippocampus.","23146751",42]
["Lidocaine","Lidocaine","D008012","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2005,"16192539","Pre- or postinsult administration of lidocaine or thiopental attenuates cell death in rat hippocampal slice cultures caused by oxygen-glucose deprivation.","16192539",42]
["Lindane","Lindane","D001556","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1993,"7513073","Effects of gamma and delta hexachlorocyclohexane isomers on inositol phosphate formation in cerebral cortex and hippocampus slices from developing and adult rat.","7513073",42]
["Lipofuscin","Lipofuscin","D008062","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1994,"7885062","Age-related accumulation of lipofuscin in three different regions of rat brain.","7885062",42]
["Lithium Chloride","Lithium Chloride","D018021","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2009,"18948125","Evidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro.","18948125",42]
["Lithium Chloride","Lithium Chloride","D018021","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1993,"7689471","Systemic administration of lithium chloride and tacrine increases nitric oxide synthase activity in the hippocampus of rats.","7689471",42]
["lomerizine","lomerizine","C052424","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"10190151","[Anti-migraine effects of lomerizine].","10190151",42]
["Lovastatin","Lovastatin","D008148","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2005,"16400415","Lovastatin reduces neuronal cell death in hippocampal CA1 subfield after pilocarpine-induced status epilepticus: preliminary results.","16400415",42]
["Lysergic Acid Diethylamide","Lysergic Acid Diethylamide","D008238","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24785760","Repeated lysergic acid diethylamide in an animal model of depression: Normalisation of learning behaviour and hippocampal serotonin 5-HT2 signalling.","24785760",42]
["lysophosphatidylinositol","lysophosphatidylinositol","C025449","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2002,"12142567","A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cultures.","12142567",42]
["magnolol","magnolol","C005498","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21518336","Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, exerts antiepileptic effects via the GABA/benzodiazepine receptor complex in mice.","21518336",42]
["manganese chloride","manganese chloride","C025340","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"25698507","Relationship between brain accumulation of manganese and aberration of hippocampal adult neurogenesis after oral exposure to manganese chloride in mice.","25698507",42]
["mecobalamin","mecobalamin","C019476","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7675316","Methylcobalamin induces a long-lasting enhancement of the postsynaptic field potential in hippocampal slices of the guinea pig.","7675316",42]
["melamine","melamine","C011907","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21867740","Melamine impairs spatial cognition and hippocampal synaptic plasticity by presynaptic inhibition of glutamatergic transmission in infant rats.","21867740",42]
["Memantine","Memantine","D008559","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16952349","Cognitive dysfunction induced by sequential injection of amyloid-beta and ibotenate into the bilateral hippocampus; protection by memantine and MK-801.","16952349",42]
["Memantine","Memantine","D008559","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2015,"25195698","Protection of Radial Glial-Like Cells in the Hippocampus of APP/PS1 Mice: a Novel Mechanism of Memantine in the Treatment of Alzheimer's Disease.","25195698",42]
["Methamphetamine","Methamphetamine","D008694","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10642852","Methamphetamine administration causes overexpression of nNOS in the mouse striatum.","10642852",42]
["Methamphetamine","Methamphetamine","D008694","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15217372","Neonatal methamphetamine administration induces region-specific long-term neuronal morphological changes in the rat hippocampus, nucleus accumbens and parietal cortex.","15217372",42]
["Methamphetamine","Methamphetamine","D008694","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21238498","Long-term effects of neonatal methamphetamine exposure on cognitive function in adolescent mice.","21238498",42]
["Methamphetamine","Methamphetamine","D008694","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"8199858","Methamphetamine-induced decrease in neural glucocorticoid receptors: relationship to monoamine levels.","8199858",42]
["Methotrexate","Methotrexate","D008727","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2010,"19828128","Inhibition of hippocampal cell proliferation by methotrexate in rats is not potentiated by the presence of a tumor.","19828128",42]
["methyl cellosolve","methyl cellosolve","C005219","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"24399739","Potential neurotoxic effect of ethylene glycol ethers mixtures.","24399739",42]
["methylazoxymethanol","methylazoxymethanol","C030667","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1999,"10575262","Abnormal connections in the malformed cortex of rats with prenatal treatment with methylazoxymethanol may support hyperexcitability.","10575262",42]
["methyleugenol","methyleugenol","C005223","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2014,"24980777","Electrophysiological characterization of methyleugenol: a novel agonist of GABA(A) receptors.","24980777",42]
["methylone","methylone","C400939","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24705904","Repeated doses of methylone, a new drug of abuse, induce changes in serotonin and dopamine systems in the mouse.","24705904",42]
["Methylphenidate","Methylphenidate","D008774","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2017,"27324900","Methylphenidate Causes Behavioral Impairments and Neuron and Astrocyte Loss in the Hippocampus of Juvenile Rats.","27324900",42]
["Metyrapone","Metyrapone","D008797","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10414433","Metyrapone alleviates ischemic neuronal damage in the gerbil hippocampus.","10414433",42]
["Midazolam","Midazolam","D008874","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"26754148","Midazolam dose correlates with abnormal hippocampal growth and neurodevelopmental outcome in preterm infants.","26754148",42]
["militarine","militarine","C545907","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2009,"19618720","[Effect and mechanism of Coeloglossum viride var. bracteatum extract on scopolamine-induced deficits of learning and memory behavior of rodents].","19618720",42]
["Minocycline","Minocycline","D008911","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2012,"22998689","Prevention of hypoglycemia-induced neuronal death by minocycline.","22998689",42]
["Molsidomine","Molsidomine","D008981","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2007,"17977674","Peroxynitrite donor impairs excitability of hippocampal CA1 neurons by inhibiting voltage-gated potassium currents.","17977674",42]
["Morphine","Morphine","D009020","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10430469","Hippocampal field CA1 interneuronal nociceptive responses: modulation by medial septal region and morphine.","10430469",42]
["Morphine","Morphine","D009020","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2005,"15911142","The dynamics of hippocampal sensory gating during the development of morphine dependence and withdrawal in rats.","15911142",42]
["Morphine","Morphine","D009020","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2010,"19282422","Involvement of PLC-beta3 in the effect of morphine on memory retrieval in passive avoidance task.","19282422",42]
["Morphine","Morphine","D009020","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2017,"28842345","Temporal effect of manipulating NeuroD1 expression with the synthetic small molecule KHS101 on morphine contextual memory.","28842345",42]
["Morphine","Morphine","D009020","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1981,"6257536","Effects of enkephalin, morphine, and naloxone on the electrical activity of the in vitro hippocampal slice preparation.","6257536",42]
["Morphine","Morphine","D009020","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1993,"8458398","In situ hybridization reveals specific increases in G alpha s and G alpha o mRNA in discrete brain regions of morphine-tolerant rats.","8458398",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C72899,B72899)","v":"Muscarine"},"Muscarine","D009116","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J72899,K72899)","v":"Hippocampus"},"D006624","Hippocampus",2,2,1992,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q72899,Q72899)","v":"1432107"},"Muscarinic potentiation of IK in hippocampal neurons: electrophysiological characterization of the signal transduction pathway.","1432107",42]
["Muscimol","Muscimol","D009118","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9990652","Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate.","9990652",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C73027,B73027)","v":"N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide"},"N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide","C090413","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J73027,K73027)","v":"Hippocampus"},"D006624","Hippocampus",2,4,2002,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q73027,Q73027)","v":"11814435"},"Effects of intra-hippocampal infusion of WAY-100635 on plus-maze behavior in mice. Influence of site of injection and prior test experience.","11814435",42]
["N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide","N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide","C090413","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9928287","5-HT1A agonist activity of pindolol: reversal of the inhibitory effects on cell firing in the dorsal raphe nucleus but not in the hippocampus by WAY-100,635.","9928287",42]
["N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine","N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine","C478058","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21756923","In vitro and in vivo characterization of the novel GABAB receptor positive allosteric modulator, 2-{1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-2-piperidinyl}ethanol (CMPPE).","21756923",42]
["Naloxone","Naloxone","D009270","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2002,"12440200","Effect of naloxone on cognitive function in vascular dementia in rats.","12440200",42]
["Naloxone","Naloxone","D009270","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1980,"6258927","Localization of naloxone-sensitive [3H]dihydromorphine binding sites within the hippocampus of the rat.","6258927",42]
["Naltrexone","Naltrexone","D009271","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2017,"28663110","Sucrose and naltrexone prevent increased pain sensitivity and impaired long-term memory induced by repetitive neonatal noxious stimulation: Role of BDNF and β-endorphin.","28663110",42]
["N-butylbenzenesulfonamide","N-butylbenzenesulfonamide","C065565","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2012,"22824510","Evaluation of N-butylbenzenesulfonamide (NBBS) neurotoxicity in Sprague-Dawley male rats following 27-day oral exposure.","22824510",42]
["neuropathiazol","neuropathiazol","C514719","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16323231","A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells.","16323231",42]
["Nicardipine","Nicardipine","D009529","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2013,"23768064","Blocking of L-type calcium channels protects hippocampal and nigral neurons against iron neurotoxicity. The role of L-type calcium channels in iron-induced neurotoxicity.","23768064",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2000,"10899361","Prenatal nicotine exposure: effects on locomotor activity and central [125I]alpha-BT binding in rats.","10899361",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16214264","Nicotine has a permissive role on the activation of metabotropic glutamate 5 receptors coexisting with nicotinic receptors on rat hippocampal noradrenergic nerve terminals.","16214264",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"17434679","Effects of chronic neonatal nicotine exposure on nicotinic acetylcholine receptor binding, cell death and morphology in hippocampus and cerebellum.","17434679",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19631612","The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices.","19631612",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21790507","Cognitive mechanisms underlying relapse to nicotine.","21790507",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2016,"26386153","Early postnatal nicotine exposure disrupts the α2* nicotinic acetylcholine receptor-mediated control of oriens-lacunosum moleculare cells during adolescence in rats.","26386153",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1969,"5783186","Effect of learning and of drugs on the ribonucleic acid concentration of brain structures of the rat.","5783186",42]
["Nicotine","Nicotine","D009538","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9454829","Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells.","9454829",42]
["Nimodipine","Nimodipine","D009553","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1990,"1979699","Diverse mechanisms of neuronal protection by nimodipine in experimental rabbit brain ischemia.","1979699",42]
["Nimustine","Nimustine","D015376","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1993,"8104817","Uptake of drugs and expression of P-glycoprotein in the rat 9L glioma.","8104817",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10487779","Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice.","10487779",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2000,"11115736","Nicotine modulates nitric oxide in rat brain.","11115736",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15380476","Clodronate inhibits the secretion of proinflammatory cytokines and NO by isolated microglial cells and reduces the number of proliferating glial cells in excitotoxically injured organotypic hippocampal slice cultures.","15380476",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"17268847","Nicotine inhibits bFGF-induced neurite outgrowth through suppression of NO synthesis in H19-7 cells.","17268847",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2008,"18367092","Ivy cells: a population of nitric-oxide-producing, slow-spiking GABAergic neurons and their involvement in hippocampal network activity.","18367092",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2010,"20638384","Alpha-synuclein induced cell death in mouse hippocampal (HT22) cells is mediated by nitric oxide-dependent activation of caspase-3.","20638384",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2015,"25817356","Co-occurrence of anxiety and depressive-like behaviors following adolescent social isolation in male mice; possible role of nitrergic system.","25817356",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"7532818","Diverse roles for nitric oxide in synaptic signalling after activation of NMDA release-regulating receptors.","7532818",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1994,"7870291","Photolytic release of nitric oxide modulates NMDA receptor-mediated transmission but does not induce long-term potentiation at hippocampal synapses.","7870291",42]
["Nitric Oxide","Nitric Oxide","D009569","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1996,"8981458","Effects of in situ manipulation of nitric oxide on rat hippocampal CA3 neurone excitability.","8981458",42]
["Nitrous Oxide","Nitrous Oxide","D009609","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2005,"15618809","Nitrous oxide (laughing gas) facilitates excitability in rat hippocampal slices through gamma-aminobutyric acid A receptor-mediated disinhibition.","15618809",42]
["N-Methyl-3,4-methylenedioxyamphetamine","N-Methyl-3,4-methylenedioxyamphetamine","D018817","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10619665","Alpha-lipoic acid prevents 3,4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity.","10619665",42]
["N-Methyl-3,4-methylenedioxyamphetamine","N-Methyl-3,4-methylenedioxyamphetamine","D018817","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"17762515","DNA fragmentation and oxidative stress in the hippocampal formation: a bridge between 3,4-methylenedioxymethamphetamine (ecstasy) intake and long-lasting behavioral alterations.","17762515",42]
["N-Methyl-3,4-methylenedioxyamphetamine","N-Methyl-3,4-methylenedioxyamphetamine","D018817","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"22983118","The neurotoxicity of hallucinogenic amphetamines in primary cultures of hippocampal neurons.","22983118",42]
["Nomifensine","Nomifensine","D009627","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15174266","[Dopaminergic regulation of theta activity of septohippocampal neuron in the awake rabbit].","15174266",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10424848","Branched-chain amino acid-induced hippocampal norepinephrine release is antagonized by picrotoxin: evidence for a central mode of action.","10424848",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2000,"11139458","Local regulation of [(3)H]-noradrenaline release from the isolated guinea-pig right atrium by P(2X)-receptors located on axon terminals.","11139458",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1425999","Nitric oxide induces neurotransmitter release from hippocampal slices.","1425999",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2005,"16364143","Noradrenergic, serotonergic and GABAergic antagonists injected together into the XII nucleus abolish the REM sleep-like depression of hypoglossal motoneuronal activity.","16364143",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1990,"1698704","Increased serotoninergic and noradrenergic activity in hepatic encephalopathy in rats with thioacetamide-induced acute liver failure.","1698704",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2009,"19568478","Enhancement of the function of rat serotonin and norepinephrine neurons by sustained vagus nerve stimulation.","19568478",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24853577","O-2050 facilitates noradrenaline release and increases the CB1 receptor inverse agonistic effect of rimonabant in the guinea pig hippocampus.","24853577",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2015,"25866202","Aging-associated formaldehyde-induced norepinephrine deficiency contributes to age-related memory decline.","25866202",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1987,"2888064","Inhibition of N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release by phencyclidine is dependent on potassium concentration.","2888064",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1988,"3233486","Hippocampus and dentate area of the European hedgehog. Comparative histochemical study.","3233486",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1985,"4021721","Differential effects of DSP-4 administration on regional brain norepinephrine turnover in rats.","4021721",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1973,"4583563","Alterations in turnover and endogenous levels of norepinephrine in cerebral cortex following electrical stimulation and acute axotomy of cerebral noradrenergic pathways.","4583563",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1970,"5536805","The effect of ascorbic acid on evoked potentials in the dorsal hippocampus by stimulation of the fornix.","5536805",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1980,"6247164","Noradrenaline inhibits depolarization-induced 3H-serotonin release from slices of rat hippocampus.","6247164",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1981,"7248812","Forebrain norepinephrine and serotonin concentrations and cardiac conditioning in normal rabbits and rabbits with septal lesions.","7248812",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7583316","Norepinephrine-independent regulation of GRII mRNA in vivo by a tricyclic antidepressant.","7583316",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1994,"7942086","Differential changes in presynaptic modulation of transmitter release during aging.","7942086",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1997,"9152369","Hippocampal noradrenaline release in awake, freely moving rats is regulated by alpha-2 adrenoceptors but not by adenosine receptors.","9152369",42]
["Norepinephrine","Norepinephrine","D009638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9384243","GV 150526A, 7-Cl-kynurenic acid and HA 966 antagonize the glycine enhancement of N-methyl-D-aspartate-induced [3H]noradrenaline and [3H]dopamine release.","9384243",42]
["NS 1231","NS 1231","C459093","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2002,"12067229","NS 1231, a novel compound with neurotrophic-like effects in vitro and in vivo.","12067229",42]
["Okadaic Acid","Okadaic Acid","D019319","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24484683","Green tea polyphenols protect against okadaic acid-induced acute learning and memory impairments in rats.","24484683",42]
["omega-Conotoxin GVIA","omega-Conotoxin GVIA","D020866","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1987,"2448660","Inhibition of central neurotransmitter release by omega-conotoxin GVIA, a peptide modulator of the N-type voltage-sensitive calcium channel.","2448660",42]
["omega-conotoxin-MVIIC","omega-conotoxin-MVIIC","C075851","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9460696","Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive Ca2+ channels.","9460696",42]
["Oseltamivir","Oseltamivir","D053139","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"17884292","Neuroexcitatory actions of Tamiflu and its carboxylate metabolite.","17884292",42]
["Ouabain","Ouabain","D010042","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1971,"4340505","[Study of limbic epileptic discharges during paradoxical sleep].","4340505",42]
["oxiracetam","oxiracetam","C040619","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1361044","Effects of oxiracetam on neurotransmitter release from rat hippocampus slices and synaptosomes.","1361044",42]
["oxymatrine","oxymatrine","C037573","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2017,"28959845","[Effect of oxymatrine on apoptosis of hippocampal neurons by p38/JNK signaling pathway].","28959845",42]
["paeonol","paeonol","C013638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27086220","Paeonol attenuates lipopolysaccharide-induced depressive-like behavior in mice.","27086220",42]
["parathelypteriside","parathelypteriside","C555340","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2010,"20800101","Parathelypteriside attenuates cognition deficits in d-galactose treated mice by increasing antioxidant capacity and improving long-term potentiation.","20800101",42]
["Particulate Matter","Particulate Matter","D052638","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21724521","Glutamatergic neurons in rodent models respond to nanoscale particulate urban air pollutants in vivo and in vitro.","21724521",42]
["p-Chloroamphetamine","p-Chloroamphetamine","D010133","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"25212999","A neurostimulant para-chloroamphetamine inhibits the arginylation branch of the N-end rule pathway.","25212999",42]
["Penicillin G","Penicillin G","D010400","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1986,"3801922","Long-term effects of sinusoidal extracellular electric fields in penicillin-treated rat hippocampal slices.","3801922",42]
["Pentobarbital","Pentobarbital","D010424","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1986,"3564684","[Effect of anticholinergic drugs alone and in combination with nembutal on burst theta-neurons of the rabbit septum].","3564684",42]
["Pentobarbital","Pentobarbital","D010424","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1983,"6320307","Biphasic actions of pentobarbital on synaptic transmission.","6320307",42]
["Pentoxifylline","Pentoxifylline","D010431","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1993,"8433093","Selective damage of hippocampal neurons in murine cerebral malaria prevented by pentoxifylline.","8433093",42]
["Pentylenetetrazole","Pentylenetetrazole","D010433","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2017,"28177664","Trimetazidine potentiates the antiepileptic activity and ameliorates the metabolic changes associated with pentylenetetrazole kindling in rats treated with valproic acid.","28177664",42]
["Pentylenetetrazole","Pentylenetetrazole","D010433","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1993,"8094739","Glutamate binding to brain membranes is increased in pentylenetetrazole-kindled rats.","8094739",42]
["perampanel","perampanel","C551441","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2013,"23480152","Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist.","23480152",42]
["Periodic Acid","Periodic Acid","D010504","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"25694088","Characterization of Periodic Acid-Schiff-Positive Granular Deposits in the Hippocampus of SJL/J Mice.","25694088",42]
["phaclofen","phaclofen","C052329","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1990,"2325880","Phaclofen antagonizes post-tetanic disinhibition in the rat dentate gyrus.","2325880",42]
["Phencyclidine","Phencyclidine","D010622","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1987,"2879908","Phencyclidine selectively inhibits N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release.","2879908",42]
["Phencyclidine","Phencyclidine","D010622","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1982,"7121744","Interactions between phencyclidine and cholinergic excitation of hippocampal pyramidal neurons.","7121744",42]
["Phenobarbital","Phenobarbital","D010634","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"17105961","Mechanism-based approaches for the reversal of drug neurobehavioral teratogenicity.","17105961",42]
["Phenylethyl Alcohol","Phenylethyl Alcohol","D010626","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27498600","Neuroprotective effects of caffeic acid phenethyl ester against sevoflurane‑induced neuronal degeneration in the hippocampus of neonatal rats involve MAPK and PI3K/Akt signaling pathways.","27498600",42]
["Phenylthiourea","Phenylthiourea","D010670","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1973,"4792476","The effect of dopamine-beta-hydroxylase inhibitors, dimethylphenylthiourea and fusaric acid, on locomotor and exploratory activity, body temperature, and regional distribution of biogenic amines in the rat brain.","4792476",42]
["Phenytoin","Phenytoin","D010672","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1988,"2454069","Phenytoin does not block hippocampal long-term potentiation or frequency potentiation.","2454069",42]
["Phenytoin","Phenytoin","D010672","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1994,"7969051","Slow binding of phenytoin to inactivated sodium channels in rat hippocampal neurons.","7969051",42]
["phosphatidylethanolamine","phosphatidylethanolamine","C483858","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2012,"22023223","Alterations in phosphatidylethanolamine levels affect the generation of Aβ.","22023223",42]
["Phosphotungstic Acid","Phosphotungstic Acid","D010772","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1973,"4129300","The fine structure of phosphotungstic acid stained neuropathologic tissue.","4129300",42]
["Physostigmine","Physostigmine","D010830","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"25446352","The role of ventral midline thalamus in cholinergic-based recovery in the amnestic rat.","25446352",42]
["Physostigmine","Physostigmine","D010830","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"7714714","Continuous administration of low dose rates of physostigmine and hyoscine to guinea-pigs prevents the toxicity and reduces the incapacitation produced by soman poisoning.","7714714",42]
["pilocarpic acid","pilocarpic acid","C029118","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2003,"14656328","Correlated stage- and subfield-associated hippocampal gene expression patterns in experimental and human temporal lobe epilepsy.","14656328",42]
["Pilocarpine","Pilocarpine","D010862","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15183516","Differential expression of brain-derived neurotrophic factor transcripts after pilocarpine-induced seizure-like activity is related to mode of Ca2+ entry.","15183516",42]
["Pilocarpine","Pilocarpine","D010862","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2008,"18186018","Comparative proteomics and correlated signaling network of rat hippocampus in the pilocarpine model of temporal lobe epilepsy.","18186018",42]
["Pilocarpine","Pilocarpine","D010862","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24909269","Dynamics of hippocampal acetylcholine release during lithium-pilocarpine-induced status epilepticus in rats.","24909269",42]
["Pilocarpine","Pilocarpine","D010862","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"7925839","Protein synthesis inhibitors attenuate seizures induced in rats by lithium plus pilocarpine.","7925839",42]
["pimagedine","pimagedine","C004479","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2008,"18395611","Neuroprotective effect of aminoguanidine on iron-induced neurotoxicity.","18395611",42]
["pioglitazone","pioglitazone","C060836","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2012,"22420664","PPARγ agonist pioglitazone improves scopolamine-induced memory impairment in mice.","22420664",42]
["Piracetam","Piracetam","D010889","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2010,"20105316","Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats.","20105316",42]
["Piracetam","Piracetam","D010889","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1986,"3594456","Comparative electrophysiological investigations on oxiracetam and piracetam.","3594456",42]
["Piribedil","Piribedil","D010891","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2001,"11356907","Antiparkinsonian agent piribedil displays antagonist properties at native, rat, and cloned, human alpha(2)-adrenoceptors: cellular and functional characterization.","11356907",42]
["Plastoquinone","Plastoquinone","D010971","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2015,"26071779","Influence of Antioxidant SkQ1 on Accumulation of Mitochondrial DNA Deletions in the Hippocampus of Senescence-Accelerated OXYS Rats.","26071779",42]
["polygalasaponin XXXII","polygalasaponin XXXII","C544870","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27180981","Polygalasaponin XXXII, a triterpenoid saponin from Polygalae Radix, attenuates scopolamine-induced cognitive impairments in mice.","27180981",42]
["Potassium Chloride","Potassium Chloride","D011189","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2001,"11383714","Modulation of K+-evoked [3H]-noradrenaline release from rat and human brain slices by gabapentin: involvement of KATP channels.","11383714",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C78211,B78211)","v":"Potassium Cyanide"},"Potassium Cyanide","D011190","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J78211,K78211)","v":"Hippocampus"},"D006624","Hippocampus",2,4,1994,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q78211,Q78211)","v":"7910421"},"Dopaminergic neurotoxicity of cyanide: neurochemical, histological, and behavioral characterization.","7910421",42]
["Prednisone","Prednisone","D011241","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"17030063","Effects of chronic prednisone therapy on mood and memory.","17030063",42]
["Pregnanolone","Pregnanolone","D011280","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"25882826","Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures.","25882826",42]
["Pregnanolone","Pregnanolone","D011280","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9651210","Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety.","9651210",42]
["prolame","prolame","C047867","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2012,"22369853","Prolame ameliorates anxiety and spatial learning and memory impairment induced by ovariectomy in rats.","22369853",42]
["Propofol","Propofol","D015742","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16949571","Pharmacological therapies against soman-induced seizures in rats 30 min following onset and anticonvulsant impact.","16949571",42]
["Propofol","Propofol","D015742","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"23519370","Propofol promotes proliferation of cultured adult rat hippocampal neural stem cells.","23519370",42]
["Propofol","Propofol","D015742","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27783647","Bumetanide, an Inhibitor of NKCC1 (Na-K-2Cl Cotransporter Isoform 1), Enhances Propofol-Induced Loss of Righting Reflex but Not Its Immobilizing Actions in Neonatal Rats.","27783647",42]
["Propranolol","Propranolol","D011433","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1990,"2101051","Locomotor activity and one-way active avoidance after intrahippocampal injection of neurotransmitter antagonists.","2101051",42]
["puerarin","puerarin","C033607","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2007,"17698307","Potential involvement of calcium and nitric oxide in protective effects of puerarin on oxygen-glucose deprivation in cultured hippocampal neurons.","17698307",42]
["pyrazole","pyrazole","C031280","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1313873","Pyrazole, an alcohol dehydrogenase inhibitor, has dual effects on N-methyl-D-aspartate receptors of hippocampal pyramidal cells: agonist and noncompetitive antagonist.","1313873",42]
["Pyridoxal Phosphate","Pyridoxal Phosphate","D011732","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1969,"5262016","L-glutamic acid, gamma-aminobutyric acid and pyridoxal-5'-phosphate at the level of the single unit in rat brain.","5262016",42]
["pyrrolidine dithiocarbamic acid","pyrrolidine dithiocarbamic acid","C020972","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19767176","Pyrrolidine dithiocarbamate protects the piriform cortex in the pilocarpine status epilepticus model.","19767176",42]
["Quercetin","Quercetin","D011794","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24480472","Quercetin improves hypoxia-ischemia induced cognitive deficits via promoting remyelination in neonatal rat.","24480472",42]
["Quinic Acid","Quinic Acid","D011801","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2012,"23010074","In vitro neurotoxic Fe(III) and Fe(III)-chelator activities in rat hippocampal cultures. From neurotoxicity to neuroprotection prospects.","23010074",42]
["Quinolinic Acid","Quinolinic Acid","D017378","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2005,"16018583","Increase of adenine nucleotide hydrolysis in rat hippocampal slices after seizures induced by quinolinic acid.","16018583",42]
["Quinolinic Acid","Quinolinic Acid","D017378","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1998,"9757068","Differentially expressed genes in hippocampal cell cultures in response to an excitotoxic insult by quinolinic acid.","9757068",42]
["QX-314","QX-314","C012647","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1735472","Intracellular effects of QX-314 and Cs+ in hippocampal pyramidal neurons in vivo.","1735472",42]
["reboxetine","reboxetine","C074679","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2001,"11750178","Effects of the selective norepinephrine reuptake inhibitor reboxetine on norepinephrine and serotonin transmission in the rat hippocampus.","11750178",42]
["Reserpine","Reserpine","D012110","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2000,"11062864","Effect of dopaminergic drugs on the reserpine-induced lowering of hippocampal theta wave frequency in rats.","11062864",42]
["Reserpine","Reserpine","D012110","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1983,"6230476","Effects of reserpine, alpha-methyl-p-tyrosine, p-chlorophenylalanine and 5,7-dihydroxytryptamine on the hippocampal kindling effect in rats.","6230476",42]
["resveratrol","resveratrol","C059514","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"26789275","Chronic administration of resveratrol prevents morphological changes in prefrontal cortex and hippocampus of aged rats.","26789275",42]
["rhyncophylline","rhyncophylline","C052714","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24140441","Effect of rhynchophylline on the expression of p-CREB and sc-Fos in triatum and hippocampal CA1 area of methamphetamine-induced conditioned place preference rats.","24140441",42]
["rimonabant","rimonabant","C089032","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16855179","CB1 receptor antagonism increases hippocampal acetylcholine release: site and mechanism of action.","16855179",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C79491,B79491)","v":"Ritonavir"},"Ritonavir","D019438","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J79491,K79491)","v":"Hippocampus"},"D006624","Hippocampus",2,4,2002,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q79491,Q79491)","v":"12387358"},"Ritonavir protects hippocampal neurons against oxidative stress-induced apoptosis.","12387358",42]
["Rolipram","Rolipram","D020889","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27058148","Rolipram improves cognition, reduces anxiety- and despair-like behaviors and impacts hippocampal neuroplasticity after transient global cerebral ischemia.","27058148",42]
["rosiglitazone","rosiglitazone","C089730","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24933538","Rosiglitazone prevents the memory deficits induced by amyloid-beta oligomers via inhibition of inflammatory responses.","24933538",42]
["RS 8359","RS 8359","C059590","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1990,"2087001","Participation of type A monoamine oxidase in the activated deamination of brain monoamines shortly after reperfusion in rats.","2087001",42]
["safingol","safingol","C005682","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1991,"1882329","Effects of protein kinase C activators and inhibitors on membrane properties, synaptic responses, and cholinergic actions in CA1 subfield of rat hippocampus in situ and in vitro.","1882329",42]
["salsolinol","salsolinol","C036617","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1988,"3216956","Tetrahydropapaveroline and salsolinol alter 45Ca2+ efflux within perfused hippocampus of unrestrained rats.","3216956",42]
["Saxitoxin","Saxitoxin","D012530","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1990,"1963107","Saxitoxin-sensitive Na+ channels: presynaptic localization in cerebellum and hippocampus of neurological mutant mice.","1963107",42]
["schizandrin A","schizandrin A","C034734","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2012,"22773410","Deoxyschizandrin isolated from the fruits of Schisandra chinensis ameliorates Aβ₁₋₄₂-induced memory impairment in mice.","22773410",42]
["Scopolamine Hydrobromide","Scopolamine Hydrobromide","D012601","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"23722831","Chronic scopolamine-injection-induced cognitive deficit on reward-directed instrumental learning in rat is associated with CREB signaling activity in the cerebral cortex and dorsal hippocampus.","23722831",42]
["Scopolamine Hydrobromide","Scopolamine Hydrobromide","D012601","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1973,"4737225","Scopolamine-induced impairment of long-term retention in rats.","4737225",42]
["Scopolamine Hydrobromide","Scopolamine Hydrobromide","D012601","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9753130","Stimulation of 5-HT1A receptors in the dorsal raphe reverses the impairment of spatial learning caused by intrahippocampal scopolamine in rats.","9753130",42]
["Selegiline","Selegiline","D012642","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"7912414","Interactions among deprenyl, clorgyline and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on catecholamines in mice.","7912414",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10210167","Modulation of 5-hydroxytryptamine release in hippocampal slices of rats: effects of fimbria-fornix lesions on 5-HT1B-autoreceptor and alpha2-heteroreceptor function.","10210167",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1999,"10422887","Hippocampal 5-HT and NE release in the transgenic rat TGR(mREN2)27 related to behavior on the elevated plus maze.","10422887",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2001,"11295428","New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey.","11295428",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2001,"11160454","Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunit.","11160454",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1975,"1141890","Effects of chronic porto-caval anastomosis on brain tryptophan, tyrosine and 5-hydroxytryptamine.","1141890",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2002,"11801362","Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice.","11801362",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2003,"12559110","Temporal patterns of limbic monoamine and plasma corticosterone response during social stress.","12559110",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2003,"12873617","Effect of the 5-HT6 receptor antagonists Ro04-6790 and Ro65-7199 on latent inhibition and prepulse inhibition in the rat: comparison to clozapine.","12873617",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1451743","Neuroprotective effect of 5-HT3 receptor antagonist on ischemia-induced decrease in CA1 field potential in rat hippocampal slices.","1451743",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"14684258","8-OH-DPAT facilitated memory consolidation and increased hippocampal and cortical cAMP production.","14684258",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C80643,B80643)","v":"Serotonin"},"Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J80643,K80643)","v":"Hippocampus"},"D006624","Hippocampus",2,4,2004,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q80643,Q80643)","v":"15285993"},"Serotonin 1A receptors in memory function.","15285993",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1990,"1689445","Effect of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine on hippocampal serotoninergic system, studied in freely moving rats.","1689445",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C80771,B80771)","v":"Serotonin"},"Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J80771,K80771)","v":"Hippocampus"},"D006624","Hippocampus",2,2,1975,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q80771,Q80771)","v":"167913"},"Physiological and pharmacological evidence for a serotonergic projection to the hippocampus.","167913",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1991,"1717650","Stress- and endotoxin-induced increases in brain tryptophan and serotonin metabolism depend on sympathetic nervous system activity.","1717650",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C80899,B80899)","v":"Serotonin"},"Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J80899,K80899)","v":"Hippocampus"},"D006624","Hippocampus",2,4,2008,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q80899,Q80899)","v":"18418367"},"Asenapine increases dopamine, norepinephrine, and acetylcholine efflux in the rat medial prefrontal cortex and hippocampus.","18418367",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2009,"19046994","Differential effects of exogenous and endogenous estrogen on anxiety as measured by elevated T-maze in relation to the serotonergic system.","19046994",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1990,"1970304","Further investigation of the in vivo pharmacological properties of the putative 5-HT1A antagonist, BMY 7378.","1970304",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2010,"20133677","N-acetylserotonin activates TrkB receptor in a circadian rhythm.","20133677",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21664256","Novelty-induced activity-regulated cytoskeletal-associated protein (Arc) expression in frontal cortex requires serotonin 2A receptor activation.","21664256",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1990,"2290946","In vivo microdialysis: a new approach for the study of functional activity of grafted monoaminergic neurons and their interaction with the host brain.","2290946",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2013,"23942622","The effects of congenital brain serotonin deficiency on responses to chronic fluoxetine.","23942622",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1988,"2454837","Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system. II. Grafts to the hippocampus.","2454837",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2016,"26100147","Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin.","26100147",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1989,"2757657","(S)-emopamil, a novel calcium and serotonin antagonist for the treatment of cerebrovascular disorders. 3rd communication: effect on postischemic cerebral blood flow and metabolism, and ischemic neuronal cell death.","2757657",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2017,"28585320","Blockade of the 5-HT transporter contributes to the behavioural, neuronal and molecular effects of cocaine.","28585320",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1987,"3673225","[The hippocampus--the monoaminergic system of the brain for sensory reinforcement].","3673225",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1973,"4269051","Serotonergic inhibition of catecholamine-induced behavioral arousal.","4269051",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1973,"4775865","The action of neuroleptics in rats with altered catecholamine metabolism. 3. The effect of chlorpromazine, haloperidol and thioridazine on the brain dopamine and serotonin contents in the rats pretreated with MAO inhibitors.","4775865",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1978,"566443","Diurnal changes in serotonin content of frontal pole and pain sensitivity in the rat.","566443",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1981,"7288654","Action of 5-hydroxytryptamine on granule cells in the rat hippocampal slice.","7288654",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1994,"7520482","Distribution and functional properties of 5-HT3 receptors in the rat hippocampal dentate gyrus: a patch-clamp study.","7520482",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7612159","The acute effects of reserpine and NSD-1015 on the brain serotonin synthesis rate measured by an autoradiographic method.","7612159",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7783947","Modulatory effects of magnolol on potassium-stimulated 5-hydroxytryptamine release from rat cortical and hippocampal slices.","7783947",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1993,"8243108","High and low affinity 5-HT2 and 5-HT1C binding sites: responses to neonatal 5,7-DHT lesions in rat brain.","8243108",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"8548293","Action potential-dependent output of 5-hydroxytryptamine in the anaesthetized rat amygdalopiriform cortex is strongly inhibited by tonic 5-HT1B-receptor stimulation.","8548293",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1996,"8734491","(-)-pindolol and (+/-)-tertatolol affect rat hippocampal 5-HT levels through mechanisms involving not only 5-HT1A, but also 5-HT1B receptors.","8734491",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1996,"8883849","Acute and chronic actions of ethanol on CA1 hippocampal responses to serotonin.","8883849",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9294972","In vivo administration of the 5-HT1A receptor agonist 8-OH-DPAT interferes with brain GABA(A)/benzodiazepine receptor complexes.","9294972",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9580577","Electrophysiological characterization of the effect of long-term duloxetine administration on the rat serotonergic and noradrenergic systems.","9580577",42]
["Serotonin","Serotonin","D012701","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1998,"9776387","The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA ('ecstasy').","9776387",42]
["sevoflurane","sevoflurane","C009250","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21872671","Post-training intra-basolateral amygdala infusions of norepinephrine block sevoflurane-induced impairment of memory consolidation and activity-regulated cytoskeletal protein expression inhibition in rat hippocampus.","21872671",42]
["sevoflurane","sevoflurane","C009250","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"26612208","Learning, memory and synaptic plasticity in hippocampus in rats exposed to sevoflurane.","26612208",42]
["shosaiko-to","shosaiko-to","C461320","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2015,"26318746","Analysis of main constituents and mechanisms underlying antidepressant-like effects of Xiaochaihutang in mice.","26318746",42]
["silicon nitride","silicon nitride","C032734","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2001,"11277967","Biocompatibility of silicon-based arrays of electrodes coupled to organotypic hippocampal brain slice cultures.","11277967",42]
["SK&F 10047","SK&F 10047","C012134","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7583231","Intrahippocampal administration of (+)-SKF 10,047, a sigma ligand, reverses MK-801-induced impairment of working memory in rats.","7583231",42]
["Sodium Azide","Sodium Azide","D019810","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1317179","Cytochrome oxidase inhibition: a novel animal model of Alzheimer's disease.","1317179",42]
["Sodium Chloride","Sodium Chloride","D012965","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1995,"7536614","Effects of strongly anisosmotic and NaCl deficient solutions on muscimol- and glutamate evoked whole-cell currents in freshly dissociated hippocampal neurons.","7536614",42]
["Sodium Oxybate","Sodium Oxybate","D012978","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2001,"11553667","gamma-Hydroxybutyrate modulation of glutamate levels in the hippocampus: an in vivo and in vitro study.","11553667",42]
["Soman","Soman","D012999","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1999,"10099835","Seizure-related opening of the blood-brain barrier produced by the anticholinesterase compound, soman: new ultrastructural observations.","10099835",42]
["Spermidine","Spermidine","D013095","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2005,"15607688","Time-dependent modulation of inhibitory avoidance memory by spermidine in rats.","15607688",42]
["Spermine","Spermine","D013096","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1995,"7583322","Spermine increases paired-pulse facilitation in area CA1 of hippocampus in a calcium-dependent manner.","7583322",42]
["spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one","spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one","C511224","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2013,"23449490","Novel cognitive enhancer ST101 enhances acetylcholine release in mouse dorsal hippocampus through T-type voltage-gated calcium channel stimulation.","23449490",42]
["Staurosporine","Staurosporine","D019311","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16715208","Staurosporin induces neurite outgrowth through ROS generation in HN33 hippocampal cell lines.","16715208",42]
["Streptomycin","Streptomycin","D013307","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1991,"1850058","Aminoglycoside antibiotics affect hippocampal LTP: a comparative study with the N-type calcium antagonist omega-conotoxin-GVIA.","1850058",42]
["Streptozocin","Streptozocin","D013311","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1997,"9248668","A low dose of streptozotocin prevents kainic acid-induced seizures and lethal effects in the rat.","9248668",42]
["Succinic Acid","Succinic Acid","D019802","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1992,"1350064","[Influence of succinate on the effectiveness of glutamatergic synaptic transmission in surviving slices of rat hippocampus].","1350064",42]
["suriclone","suriclone","C037283","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1983,"6316990","Differences between cyclopyrrolones (suriclone and zopiclone) and benzodiazepine binding to rat hippocampus photolabelled membranes.","6316990",42]
["Tacrine","Tacrine","D013619","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1987,"2446884","Tetrahydroaminoacridine blocks voltage-dependent ion channels in hippocampal neurons.","2446884",42]
["Tacrolimus","Tacrolimus","D016559","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1998,"9651198","Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.","9651198",42]
["Taurine","Taurine","D013654","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2000,"10677142","Effects of taurine on ozone-induced memory deficits and lipid peroxidation levels in brains of young, mature, and old rats.","10677142",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C83331,B83331)","v":"Taurine"},"Taurine","D013654","5_KE",756,5,"Hippocampal gene expression","Altered",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J83331,K83331)","v":"Hippocampus"},"D006624","Hippocampus",2,4,2004,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q83331,Q83331)","v":"15370179"},"Antioxidant effects of taurine, vitamin C, and vitamin E on oxidative damage in hippocampus caused by the administration of 3-nitropropionic acid in rats.","15370179",42]
["Taurine","Taurine","D013654","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2013,"22828811","Modulation of taurine release in glucose-free media by glutamate receptors in hippocampal slices from developing and adult mice.","22828811",42]
["Taurine","Taurine","D013654","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1974,"4271319","Zinc, taurine, and epilepsy.","4271319",42]
["tenocyclidine","tenocyclidine","C012058","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1988,"3280329","Comparison of the effects of MK-801 and phencyclidine on catecholamine uptake and NMDA-induced norepinephrine release.","3280329",42]
["tert-butylbicyclophosphorothionate","tert-butylbicyclophosphorothionate","C037476","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1994,"7834364","The protective effects of stress control may be mediated by increased brain levels of benzodiazepine receptor agonists.","7834364",42]
["Tetraethylammonium","Tetraethylammonium","D019789","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2009,"19276590","Comparison of the L-glutamate level in mouse hippocampal slices under tetraethylammonium chloride stimulation as measured with a glass capillary sensor and a patch sensor.","19276590",42]
["Tetrodotoxin","Tetrodotoxin","D013779","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1990,"2167134","[Tetrodotoxin--a sensitive component of the depolarizing response to GABA administration to the pyramidal neuron dendrites of the CA1 field of the hippocampus].","2167134",42]
["Theobromine","Theobromine","D013805","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15385357","The anticonvulsant action of propofol on epileptiform activity in rat hippocampal slices.","15385357",42]
["Thiamine","Thiamine","D013831","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2001,"11640948","Co-culture with astrocytes or microglia protects metabolically impaired neurons.","11640948",42]
["Thioacetamide","Thioacetamide","D013853","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1997,"9437665","Lectin histochemistry of the rat brain following thioacetamide-induced hepatic failure.","9437665",42]
["Thiourea","Thiourea","D013890","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2003,"12946612","Waking selective neurons in the posterior hypothalamus and their response to histamine H3-receptor ligands: an electrophysiological study in freely moving cats.","12946612",42]
["tiagabine","tiagabine","C059205","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2002,"12094558","Recurrent complex partial status epilepticus associated with tiagabine rechallenge.","12094558",42]
["tianeptine","tianeptine","C050504","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2008,"17826881","Tianeptine: potential influences on neuroplasticity and novel pharmacological effects.","17826881",42]
["tirilazad","tirilazad","C053355","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1990,"2282527","Failure of the lipid peroxidation inhibitor U74006F to improve neurological outcome after transient forebrain ischemia in the rat.","2282527",42]
["Toluene","Toluene","D014050","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9273439","[Changes in bioelectric function of rabbit cerebral cortex after intraperitoneal injection of organic solvents. I. Toluene and m-xylene].","9273439",42]
["topiramate","topiramate","C052342","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2008,"18289475","[Neuroprotective effects of topiramate and folic acid on young rats with kindling-induced epilepsy].","18289475",42]
["Tranylcypromine","Tranylcypromine","D014191","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2004,"15145706","Zinc treatment induces cortical brain-derived neurotrophic factor gene expression.","15145706",42]
["Trichlorfon","Trichlorfon","D014236","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9449438","Effects of metrifonate on radial arm maze acquisition in middle-aged rats.","9449438",42]
["trichostatin A","trichostatin A","C012589","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2010,"20633124","Effects of histone deacetylase inhibitor Trichostatin A on epigenetic changes and transcriptional activation of Bdnf promoter 1 by rat hippocampal neurons.","20633124",42]
["trimethyltin","trimethyltin","C046488","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2002,"12429238","Expression of EMAP-II by activated monocytes/microglial cells in different regions of the rat hippocampus after trimethyltin-induced brain damage.","12429238",42]
["trimethyltin","trimethyltin","C046488","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2012,"23063466","Possible involvement of galectin-3 in microglial activation in the hippocampus with trimethyltin treatment.","23063466",42]
["trimethyltin","trimethyltin","C046488","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1994,"7894332","The neuroprotective effect of tacrine on trimethyltin induced memory and muscarinic receptor dysfunction in the rat.","7894332",42]
["tryptoline","tryptoline","C009804","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1985,"4041928","Monoamine transmitter release induced by tetrahydro-beta-carboline perfused in hippocampus of the unrestrained rat.","4041928",42]
["U 69593","U 69593","C045444","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1999,"10515966","Dynorphin selectively augments the M-current in hippocampal CA1 neurons by an opiate receptor mechanism.","10515966",42]
["Ubiquinone","Ubiquinone","D014451","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2011,"20584203","Neuropharmacological effects of lipoic acid and ubiquinone on the mRNA level of interleukin-1β and acetylcholinesterase activity in rat hippocampus after seizures.","20584203",42]
["Uric Acid","Uric Acid","D014527","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27798180","Uric Acid Induces Cognitive Dysfunction through Hippocampal Inflammation in Rodents and Humans.","27798180",42]
["Valproic Acid","Valproic Acid","D014635","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2006,"16460767","Effects of mood stabilizers on hippocampus BDNF levels in an animal model of mania.","16460767",42]
["Valproic Acid","Valproic Acid","D014635","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2011,"21543053","Valproic acid induces apoptosis in differentiating hippocampal neurons by the release of tumor necrosis factor-α from activated astrocytes.","21543053",42]
["Valproic Acid","Valproic Acid","D014635","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1988,"3145780","Sodium valproate decreases synaptic potentiation and epileptiform activity in hippocampus.","3145780",42]
["Venlafaxine Hydrochloride","Venlafaxine Hydrochloride","D000069470","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2010,"20651837","Chronic effects of venlafaxine on synaptophysin and neuronal cell adhesion molecule in the hippocampus of cerebral ischemic mice.","20651837",42]
["Verapamil","Verapamil","D014700","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,1985,"3001573","Evidence for down-regulation of 3H-nitrendipine recognition sites in mouse brain after long-term treatment with nifedipine or verapamil.","3001573",42]
["vesamicol","vesamicol","C006189","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1997,"9375695","Effect of protein kinase C activation on the release of [3H]acetylcholine in the presence of vesamicol.","9375695",42]
["Vitamin E","Vitamin E","D014810","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,1999,"10334572","Vitamin E prevents apoptosis in hippocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats.","10334572",42]
["Vitamin E","Vitamin E","D014810","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,2,2012,"22120593","Lysosomal vitamin E accumulation in Niemann-Pick type C disease.","22120593",42]
["vortioxetine","vortioxetine","C557874","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"26711685","Vortioxetine promotes early changes in dendritic morphology compared to fluoxetine in rat hippocampus.","26711685",42]
["Water","Water","D014867","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2014,"24967689","Oral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats.","24967689",42]
["xiaobuxin-tang","xiaobuxin-tang","C532342","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2008,"18547700","The total flavonoids extracted from Xiaobuxin-Tang up-regulate the decreased hippocampal neurogenesis and neurotrophic molecules expression in chronically stressed rats.","18547700",42]
["Yohimbine","Yohimbine","D015016","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2016,"27557950","Neonatal domoic acid alters in vivo binding of [11C]yohimbine to α2-adrenoceptors in adult rat brain.","27557950",42]
["zearalenol","zearalenol","C029659","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2007,"18064574","Protective effects of phytoestrogen alpha-zearalanol on beta amyloid25-35 induced oxidative damage in cultured rat hippocampal neurons.","18064574",42]
["zinc chloride","zinc chloride","C016837","5_KE",756,5,"Hippocampal gene expression","Altered","Hippocampus","D006624","Hippocampus",2,4,2018,"29548726","Disruption of the zinc metabolism in rat fœtal brain after prenatal exposure to cadmium.","29548726",42]
["Amphetamine","Amphetamine","D000661","8_AO",402,8,"Cognitive Function","Decreased","Intelligence","D007360","Intelligence",0,1,1966,"4861659","[Structural changes in the intelligence factors under the influence of amphetamine].","4861659",42]
["Cocaine","Cocaine","D003042","8_AO",402,8,"Cognitive Function","Decreased","Intelligence","D007360","Intelligence",0,1,2004,"15487596","Infant joint attention skill and preschool behavioral outcomes in at-risk children.","15487596",42]
["Diethylstilbestrol","Diethylstilbestrol","D004054","8_AO",402,8,"Cognitive Function","Decreased","Intelligence","D007360","Intelligence",0,1,1992,"1398561","Prenatal diethylstilbestrol exposure and performance on college entrance examinations.","1398561",42]
["Fenfluramine","Fenfluramine","D005277","8_AO",402,8,"Cognitive Function","Decreased","Intelligence","D007360","Intelligence",0,1,1989,"2606883","The effects of fenfluramine (hydrochloride) on the behaviors of fifteen autistic children.","2606883",42]
["Methylphenidate","Methylphenidate","D008774","8_AO",402,8,"Cognitive Function","Decreased","Intelligence","D007360","Intelligence",0,1,1974,"4598851","Imipramine and methylphenidate treatments of hyperactive boys. A double-blind comparison.","4598851",42]
["phthalic acid","phthalic acid","C032279","8_AO",402,8,"Cognitive Function","Decreased","Intelligence","D007360","Intelligence",0,1,2010,"20194078","Relationship between environmental phthalate exposure and the intelligence of school-age children.","20194078",42]
["Sodium Chloride, Dietary","Sodium Chloride, Dietary","D017673","8_AO",402,8,"Cognitive Function","Decreased","Intelligence","D007360","Intelligence",0,1,2008,"18205986","Iodine deficiency and its association with intelligence quotient in schoolchildren from Colima, Mexico.","18205986",42]
["Valproic Acid","Valproic Acid","D014635","8_AO",402,8,"Cognitive Function","Decreased","Intelligence","D007360","Intelligence",0,1,2004,"14718692","Normal intelligence in children with prenatal exposure to carbamazepine.","14718692",42]
["3,4,3',4'-tetrachlorobiphenyl","3,4,3',4'-tetrachlorobiphenyl","C028451","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,1993,"8378931","Interference of polychlorinated biphenyls in hepatic and brain thyroid hormone metabolism in fetal and neonatal rats.","8378931",42]
["acetochlor","acetochlor","C043377","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,4,2016,"26397822","Thyroid endocrine disruption of acetochlor on zebrafish (Danio rerio) larvae.","26397822",42]
["Amiodarone","Amiodarone","D000638","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,4,1986,"3703637","Amiodarone therapy effects on childhood thyroid function.","3703637",42]
["Calcium, Dietary","Calcium, Dietary","D002136","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,2012,"22789468","Dietary calcium induced cytological and biochemical changes in thyroid.","22789468",42]
["Cholecalciferol","Cholecalciferol","D002762","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,2009,"20097959","Vitamin D3 affects expression of thyroid hormone receptor alpha and deiodinase activity in liver of MNU-treated Sprague-Dawley rats.","20097959",42]
["cyanogen","cyanogen","C011206","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Iodide Peroxidase","D007453","Iodide Peroxidase",2,4,2015,"25872244","Synergic actions of polyphenols and cyanogens of peanut seed coat (Arachis hypogaea) on cytological, biochemical and functional changes in thyroid.","25872244",42]
["Desipramine","Desipramine","D003891","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,1990,"2287651","Chronic desimipramine treatment enhances thyroxine deiodination in rat brain.","2287651",42]
["Ethanol","Ethanol","D000431","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,1998,"9489935","Effects of acute administration of ethanol and the mu-opiate agonist etonitazene on thyroid hormone metabolism in rat brain.","9489935",42]
["genapol X 080","genapol X 080","C116996","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,2000,"11011223","Possible activation of auto-immune thyroiditis from continuous subcutaneous infusion of genapol-containing insulin.","11011223",42]
["HBME-1 antigen","HBME-1 antigen","C432845","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,2008,"18212751","Utility of malignancy markers in fine-needle aspiration cytology of thyroid nodules: comparison of Hector Battifora mesothelial antigen-1, thyroid peroxidase and dipeptidyl aminopeptidase IV.","18212751",42]
["Iopanoic Acid","Iopanoic Acid","D007480","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,1986,"3743648","Influence of pharmacological doses of iopanoic acid and thyroxine 5- and 5'-monodeiodination in liver and kidney of the pig.","3743648",42]
["Maneb","Maneb","D008344","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Iodide Peroxidase","D007453","Iodide Peroxidase",2,3,1997,"9418944","Studies on rat thyroid after oral administration of mancozeb: morphological and biochemical evaluations.","9418944",42]
["Methimazole","Methimazole","D008713","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,1999,"10482369","Antithyroid drugs inhibit radioiodine-induced increases in thyroid autoantibodies in hyperthyroid Graves' disease.","10482369",42]
["methyl triclosan","methyl triclosan","C502486","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,2011,"21574574","Effects of triclocarban, triclosan, and methyl triclosan on thyroid hormone action and stress in frog and mammalian culture systems.","21574574",42]
["perfluorohexanesulfonic acid","perfluorohexanesulfonic acid","C471071","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,2012,"22302310","In ovo effects of perfluorohexane sulfonate and perfluorohexanoate on pipping success, development, mRNA expression, and thyroid hormone levels in chicken embryos.","22302310",42]
["pioglitazone","pioglitazone","C060836","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,2016,"27324467","Pioglitazone, a PPARγ Agonist, Upregulates the Expression of Caveolin-1 and Catalase, Essential for Thyroid Cell Homeostasis: A Clue to the Pathogenesis of Hashimoto's Thyroiditis.","27324467",42]
["Propranolol","Propranolol","D011433","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,1991,"1771951","[Letter to the Zeitschrift für Gastroenterologie concerning the paper by Ljubicić et al., 1991; 29: 286-8].","1771951",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,1994,"8051490","Soluble CD antigen (cytokine) expression in various hyperthyroid states and use in the assessment of propylthiouracil treatment.","8051490",42]
["Propylthiouracil","Propylthiouracil","D011441","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,4,1996,"8641212","Comparison of the effects of propylthiouracil and selenium deficiency on T3 production in the rat.","8641212",42]
["Sodium Selenite","Sodium Selenite","D018038","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,2011,"20517655","Supplemental selenium alleviates the toxic effects of excessive iodine on thyroid.","20517655",42]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Iodide Peroxidase","D007453","Iodide Peroxidase",2,2,1991,"2002332","Induction of 5-deiodinase activity in astroglial cells by 12-O-tetradecanoylphorbol 13-acetate and fibroblast growth factors.","2002332",42]
["Thiouracil","Thiouracil","D013889","1_MIE",279,1,"Thyroperoxidase","Inhibition","Iodide Peroxidase","D007453","Iodide Peroxidase",2,4,1978,"744122","The irreversible inactivation of thyroid peroxidase by methylmercaptoimidazole, thiouracil, and propylthiouracil in vitro and its relationship to in vivo findings.","744122",42]
["zinc chloride","zinc chloride","C016837","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Iodide Peroxidase","D007453","Iodide Peroxidase",2,4,1986,"3713445","Substrate specificity of iodothyronine 5'-deiodinase in rat liver homogenates and its requirements of divalent cations in vitro.","3713445",42]
["14-iodo-15-hydroxyeicosatrienoic acid, omega lactone","14-iodo-15-hydroxyeicosatrienoic acid, omega lactone","C030074","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1992,"1284329","Further studies on the antigoitrogenic action of iodoarachidonates.","1284329",42]
["2,2',4,4',5-brominated diphenyl ether","2,2',4,4',5-brominated diphenyl ether","C477694","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2014,"25210006","Dietary exposure of BDE-47 and BDE-99 and effects on behavior, bioenergetics, and thyroid function in juvenile red-eared sliders (Trachemys scripta elegans) and common snapping turtles (Chelydra serpentina).","25210006",42]
["2,4,5,2',4',5'-hexachlorobiphenyl","2,4,5,2',4',5'-hexachlorobiphenyl","C014024","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1993,"8516785","Effects of perinatal exposure to specific PCB congeners on thyroid hormone concentrations and thyroid histology in the rat.","8516785",42]
["3-cyclobutene-1,2-dione","3-cyclobutene-1,2-dione","C110624","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2008,"18585912","Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor beta (TR-beta) selective ligands.","18585912",42]
["4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid","4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid","D012856","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1985,"2580839","Effect of anion-specific inhibitors on the utilization of sugar nucleotides for N-linked carbohydrate unit assembly by thyroid endoplasmic reticulum vesicles.","2580839",42]
["5-Methoxytryptamine","5-Methoxytryptamine","D008735","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1985,"3865796","[Comparative experimental study of the effect of melatonin and 5-methoxytryptamine on the thyroid gland of rats].","3865796",42]
["Acetylcholine","Acetylcholine","D000109","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2003,"14507058","The adrenergic and cholinergic innervation of the thyroid chicken gland.","14507058",42]
["adroxazine","adroxazine","C045437","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1986,"3816024","Roles of adroxazine, a new heterocyclic hormone of the adrenals, and leucogenenol, a thymothyroid hormone, in the formation of blood cells.","3816024",42]
["Allylamine","Allylamine","D000499","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1982,"7151982","Coronary and thyroid arteriopathy induced by allylamine and beta-aminopropionitrile.","7151982",42]
["Aminoglutethimide","Aminoglutethimide","D000616","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1980,"6249490","The use of aminoglutethimide in the treatment of patients with metastatic carcinoma of the breast.","6249490",42]
["Amiodarone","Amiodarone","D000638","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2009,"19942150","Amiodarone and thyroid.","19942150",42]
["Amiodarone","Amiodarone","D000638","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1989,"2484863","24 h-kinetics of iodide uptake in amiodarone induced hypothyroidism.","2484863",42]
["Amiodarone","Amiodarone","D000638","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1987,"3310068","Amiodarone and the thyroid.","3310068",42]
["Amiodarone","Amiodarone","D000638","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1984,"6387328","Clinical use and pharmacology of amiodarone.","6387328",42]
["ammonium perchlorate","ammonium perchlorate","C053506","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2003,"14680992","Oral (drinking water) developmental toxicity study of ammonium perchlorate in Sprague-Dawley rats.","14680992",42]
["Amphetamine","Amphetamine","D000661","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1948,"18939225","Results of prolonged medical treatment of obesity with diet alone, diet and thyroid preparations, and diet and amphetamine.","18939225",42]
["Arachidonic Acid","Arachidonic Acid","D016718","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1999,"10510591","Phospholipase C activation by Na+/Ca2+ exchange is essential for monensin-induced Ca2+ influx and arachidonic acid release in FRTL-5 thyroid cells.","10510591",42]
["Ascorbic Acid","Ascorbic Acid","D001205","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1972,"4336354","[Characteristics of the functional state of the thyroid gland in hyperthermia].","4336354",42]
["Bendroflumethiazide","Bendroflumethiazide","D001539","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1971,"5171946","The effect of bendroflumethiazide (Centyl) on the renal excretion of calcium and sodium in normal, parathyroidectomized, thyroidectomized and thyroparathyroidectomized rats.","5171946",42]
["beta-Aminoethyl Isothiourea","beta-Aminoethyl Isothiourea","D000338","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1967,"5588052","Effect of radioprotective compounds such as beta-aminoethylisothiouronium (AET) and MERCAPTOETHYLGUANIDINE (MEG) on the thyroid gland of Heteropneustes fossilis Bloch.","5588052",42]
["bisphenol A","bisphenol A","C006780","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2016,"27869686","The Association of Serum Bisphenol A with Thyroid Autoimmunity.","27869686",42]
["Blood Glucose","Blood Glucose","D001786","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1972,"4111374","Thyroid function, plasma insulin, glucose and ketones and in vitro hepatic gluconeogenesis in rats under chronic low iodine intake.","4111374",42]
["Calcimycin","Calcimycin","D000001","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1979,"222640","Effects of carbamylcholine and ionophore A-23187 on cyclic 3',5'-AMP and cyclic 3',5'-GMP accumulation in dog-thyroid slices.","222640",42]
["Calcium Chloride","Calcium Chloride","D002122","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2013,"24274889","Assessment of calcitonin response to experimentally induced hypercalcemia in cats.","24274889",42]
["Calcium, Dietary","Calcium, Dietary","D002136","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1963,"13969101","Thyroid-parathyroid interrelationship in processes governing myocardial calcification.","13969101",42]
["Carbidopa","Carbidopa","D002230","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1979,"572939","Sinemet and thyroid function in Parkinson disease.","572939",42]
["Carbimazole","Carbimazole","D002231","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1978,"721696","Mitotic rate of the rat's thyroid gland during hypertrophy induced by an antithyroid agent (carbimazole).","721696",42]
["Carnitine","Carnitine","D002331","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1965,"5888936","[Effect of carnitine of the accumulation of iodine in the thyroid gland].","5888936",42]
["Catechin","Catechin","D002392","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2013,"23117228","Catechin induced modulation in the activities of thyroid hormone synthesizing enzymes leading to hypothyroidism.","23117228",42]
["Chlorpromazine","Chlorpromazine","D002746","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1959,"13823702","Effect of chlorpromazine on thyroid activity.","13823702",42]
["Chlorpropamide","Chlorpropamide","D002747","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1966,"5993213","[The action of chlorpropamide (Diabenese), carbutamide (Glucophren) and iversal on thyroid function in rats].","5993213",42]
["Cholecalciferol","Cholecalciferol","D002762","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1974,"4372133","Comparative studies on the behavior of C cells in the rat thyroid under conditions of hypercalcemia induced with vitamin D3 and calcium gluconate.","4372133",42]
["Cholesterol","Cholesterol","D002784","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1965,"14327270","HYDROCORTISONE AND/OR DESICCATED THYROID IN PHYSIOLOGIC DOSAGE. XVII. MAJOR AND MINOR THYROIDAL INDICES DURING THERAPY WITH LARGE DOSAGES OF DESICCATED THYROID.","14327270",42]
["Cholesterol","Cholesterol","D002784","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2014,"24866829","A firmer understanding of the effect of hypergravity on thyroid tissue: cholesterol and thyrotropin receptor.","24866829",42]
["Cholesterol","Cholesterol","D002784","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1971,"5578922","In vitro studies on the effect of different dietary fats and different proportions of dietary protein on the synthesis of lipids by rat arterial tissue.","5578922",42]
["Cholesterol, Dietary","Cholesterol, Dietary","D002791","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1981,"6976263","Possible mechanism of action of cholesterol enriched diet on the thyroid.","6976263",42]
["Cocaine","Cocaine","D003042","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1985,"2999657","New concepts in cocaine addiction: the dopamine depletion hypothesis.","2999657",42]
["Colforsin","Colforsin","D005576","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1987,"2443593","Forskolin and thyrotrophin stimulation of rat FRTL-5 thyroid cell growth: the role of cyclic AMP.","2443593",42]
["Creatinine","Creatinine","D003404","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2006,"17037243","Creatinine, blood urea nitrogen and thyroid hormone levels before and after haemodialysis.","17037243",42]
["Cyclophosphamide","Cyclophosphamide","D003520","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1979,"582025","Thyroid binding antibodies and other immunological abnormalities in patients with Graves' ophthalmopathy: effect of treatment with cyclophosphamide.","582025",42]
["Dehydroascorbic Acid","Dehydroascorbic Acid","D003683","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2017,"29084538","Expression of hypoxia inducible factor 1α and 2α and its association with vitamin C level in thyroid lesions.","29084538",42]
["Dexamethasone","Dexamethasone","D003907","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2009,"19850691","Prevention of relapse of Graves' disease by treatment with an intrathyroid injection of dexamethasone.","19850691",42]
["Dexamethasone","Dexamethasone","D003907","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1994,"8022953","A further investigation of basal HPT axis function in unipolar depression: effects of diagnosis, hospitalization, and dexamethasone administration.","8022953",42]
["Diazepam","Diazepam","D003975","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1971,"4103285","Effect of diazepam (Valium) on dialysable thyroxime.","4103285",42]
["Diff Quik","Diff Quik","C067461","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2011,"21416641","Ultrasound gel artifact on Diff-Quik stained thyroid fine-needle aspirate smears.","21416641",42]
["diisopropanolnitrosamine","diisopropanolnitrosamine","C012457","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2009,"19572977","Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation.","19572977",42]
["Dinoprostone","Dinoprostone","D015232","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1985,"2981713","Effects of prostaglandin E2 and cholera toxin on apical sodium uptake in thyroid epithelial cells: role of cAMP.","2981713",42]
["Dopamine","Dopamine","D004298","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1966,"5920691","Monoaminergic mechanisms in parafollicular cells of the mouse thyroid gland.","5920691",42]
["Durapatite","Durapatite","D017886","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2007,"17417108","Functional outcome of vocal fold medialization thyroplasty with a hydroxyapatite implant.","17417108",42]
["Epinephrine","Epinephrine","D004837","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1952,"12977270","[Effects of adrenalin and arterenol and thyroid hormone].","12977270",42]
["Epinephrine","Epinephrine","D004837","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1964,"14145683","EFFECT OF AURANTIN ON ENDOCRINE SYSTEM.","14145683",42]
["Epoprostenol","Epoprostenol","D011464","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1984,"6419786","Modulation of prostaglandin E2, F2 alpha, I2 content and synthesis by thyrotropin in cultured porcine thyroid cells and intact rat thyroid glands.","6419786",42]
["Ethanol","Ethanol","D000431","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2005,"15865257","Subchronic toxicity of a fluoroalkylethanol mixture in rats.","15865257",42]
["Ethanol","Ethanol","D000431","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1984,"6361409","The effects of alcohol on the endocrine system.","6361409",42]
["Ethylenebis(dithiocarbamates)","Ethylenebis(dithiocarbamates)","D005028","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1986,"3468914","Ethylenethiourea and nabam induced alterations of function and morphology of thyroid gland in rats.","3468914",42]
["Fluorodeoxyglucose F18","Fluorodeoxyglucose F18","D019788","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2007,"17198352","The significance of FDG uptake in bilateral thyroid glands.","17198352",42]
["Fluorodeoxyglucose F18","Fluorodeoxyglucose F18","D019788","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2016,"27612034","The incidence of thyroid cancer in focal hypermetabolic thyroid lesions: an 18F-FDG PET/CT study in more than 6000 patients.","27612034",42]
["Fluorouracil","Fluorouracil","D005472","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1976,"56692","Letter: 5-fluorouracil and the thyroid.","56692",42]
["Galactose","Galactose","D005690","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1989,"2914955","Characterization of a thyroid sulfotransferase responsible for the 3-O-sulfation of terminal beta-D-galactosyl residues in N-linked carbohydrate units.","2914955",42]
["gluconic acid","gluconic acid","C030691","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1965,"14323617","PYRIDINE NUCLEOTIDES IN THE THYROID. 3. A METHOD FOR DETERMINATION OF OXIDIZED AND REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDES USING 6-PHOSPHO-(I14C)-GLUCONATE.","14323617",42]
["Glucose","Glucose","D005947","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1960,"13822679","Stimulation in vitro of pathways of glucose oxidation in thyroid by thyroid-stimulating hormone.","13822679",42]
["Glucose","Glucose","D005947","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1962,"14477164","Effect of propylthiouracil and thyroid-stimulating hormone on glucose oxidation in rat thyroid tissue.","14477164",42]
["Glucose","Glucose","D005947","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1996,"8605001","Glucose may induce cell death through a free radical-mediated mechanism.","8605001",42]
["Glycogen","Glycogen","D006003","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1968,"4299706","Levels of enzymes involved in glycolysis, gluconeogenesis, glycogenesis and hexosemonophosphate shunt in rat thyroid.","4299706",42]
["Haloperidol","Haloperidol","D006220","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1976,"958594","Differential effects of dopamine agonists and haloperidol on release of prolactin, thyroid stimulating hormone, growth hormone and luteinizing hormone in rats.","958594",42]
["Heparin","Heparin","D006493","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1983,"6639382","[Effect of heparin on the thyroid gland].","6639382",42]
["Histamine","Histamine","D006632","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1972,"4664395","The effect of the thyroid gland on the histamine and 5-hydroxytryptamine level of dog, rabbit and rat tissues.","4664395",42]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2000,"10849441","Role of peroxiredoxins in regulating intracellular hydrogen peroxide and hydrogen peroxide-induced apoptosis in thyroid cells.","10849441",42]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1990,"2162123","Hydrogen peroxide inhibits iodide influx and enhances iodide efflux in cultured FRTL-5 rat thyroid cells.","2162123",42]
["Hydrogen Peroxide","Hydrogen Peroxide","D006861","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1983,"6297736","Cytochemical demonstration of an enzymatic production of hydrogen peroxide on the surface of isolated thyroid capillaries.","6297736",42]
["Indomethacin","Indomethacin","D007213","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1976,"820703","The effect of aspirin and indomethacin on the TRH response in man.","820703",42]
["Inulin","Inulin","D007444","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1977,"188285","Uptake of macromolecules by the thyroid.","188285",42]
["Iodized Oil","Iodized Oil","D007459","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1980,"6245539","[Effect of lipiodol \"ultra-fluid\" used for intrathyroid lymphography on the blood serum levels of thyroxine and triiodothyronine].","6245539",42]
["Iopanoic Acid","Iopanoic Acid","D007480","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2001,"11344170","Clinical review 129: Oral cholecystographic agents and the thyroid.","11344170",42]
["Isoproterenol","Isoproterenol","D007545","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1978,"221522","Thyrotoxicosis: comparison of effects of thyroid ablation and beta-adrenergic blockade on metabolic rate and ventilatory control.","221522",42]
["Ketoprofen","Ketoprofen","D007660","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2006,"16805931","The effect of fentanyl and remifentanil, with or without ketoprofen, on pain after thyroid surgery: a randomized-controlled trial.","16805931",42]
["leptine I","leptine I","C410862","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2012,"22051776","Regulation of lipin1 by nutritional status, adiponectin, sex and pituitary function in rat white adipose tissue.","22051776",42]
["Lithium Carbonate","Lithium Carbonate","D016651","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2002,"12113923","Thyroid echogenicity in manic-depressive patients receiving lithium therapy.","12113923",42]
["malachite green","malachite green","C005095","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1999,"10682936","Toxicity and metabolism of malachite green and leucomalachite green during short-term feeding to Fischer 344 rats and B6C3F1 mice.","10682936",42]
["Maneb","Maneb","D008344","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1993,"8406605","Effect of oral administration of fungicide-mancozeb on thyroid gland of rat.","8406605",42]
["menadiol","menadiol","C023885","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1961,"13724946","Stimulation in vitro of hexose monophosphate pathway in thyroid by iodotyrosines and synkavit.","13724946",42]
["Methimazole","Methimazole","D008713","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2002,"12150331","Thyroid function and intellectual development of children of mothers taking methimazole during pregnancy.","12150331",42]
["Methimazole","Methimazole","D008713","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1992,"1543017","Thyroid hypoechogenic pattern at ultrasonography as a tool for predicting recurrence of hyperthyroidism after medical treatment in patients with Graves' disease.","1543017",42]
["Methimazole","Methimazole","D008713","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1990,"2171921","Changes in serum autoantibodies to thyroid peroxidase during antithyroid drug therapy for Graves' disease.","2171921",42]
["Methimazole","Methimazole","D008713","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1988,"3139552","Methimazole blocks Graves' IgG but not interferon-gamma HLA-DR expression by thyroid cells.","3139552",42]
["Methimazole","Methimazole","D008713","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1997,"9487039","[The effect of the long-term intake of merkazolil by the thyroid on the thermoregulatory activity of motor units in cold-adapted rats].","9487039",42]
["Methylene Blue","Methylene Blue","D008751","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1966,"4380739","Inhibition of thyroidal deiodination of diiodotyrosine by compounds which enhance NADPH oxidation.","4380739",42]
["Methylthiouracil","Methylthiouracil","D008779","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1958,"13560557","[Studies of growth hormone preparations in rats following thyroid block by methylthiouracil].","13560557",42]
["Methylthiouracil","Methylthiouracil","D008779","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1949,"15393267","[Hyperthyroidism and hyperthyroid cardiopathy; its treatment with thiouracil, methylthiouracil and propylthiouracil].","15393267",42]
["Methylthiouracil","Methylthiouracil","D008779","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1972,"4342784","[Chronological course of the effect of thyroid hormones and goitrogens on the accumulation of radioactive iodine in the rat].","4342784",42]
["Methylthiouracil","Methylthiouracil","D008779","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1968,"5728480","[Bioelectrical activity in the rat brain after injection of thyroidine and 6-methylthiouracile under stress and adrenalectomy].","5728480",42]
["Metyrapone","Metyrapone","D008797","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1972,"4335579","Ultrastructural changes in the adenohypophysis of metyrapone-treated rabbits.","4335579",42]
["Morphine","Morphine","D009020","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1965,"5853693","The effects of morphine, chlorpromazine and reserpine on pituitary-thyroid activity in rats.","5853693",42]
["N-acetylsphingosine","N-acetylsphingosine","C064769","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2001,"11724323","Involvement of wild-type p53 in radiation-induced c-Jun N-terminal kinase activation in human thyroid cells.","11724323",42]
["Niacinamide","Niacinamide","D009536","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1964,"14264372","NAD+-GLYCOHYDROLASE OF THYROID HOMOGENATES.","14264372",42]
["Nifedipine","Nifedipine","D009543","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1985,"2411262","Effect of calcium channel agonist Bay K 8644 on calcitonin secretion from a rat C-cell line.","2411262",42]
["Norepinephrine","Norepinephrine","D009638","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1989,"2614014","Norepinephrine and TSH: effects on thyroidal radioiodine and thyroxine release.","2614014",42]
["Norepinephrine","Norepinephrine","D009638","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1982,"6274625","Involvement of alpha 1-adrenergic receptors in the inhibitory effect of catecholamines on the thyrotropin-induced release of thyroxine by the mouse thyroid.","6274625",42]
["Norethindrone","Norethindrone","D009640","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1981,"6786825","Phase I clinical trial of two contraceptive preparations. Norethisterone enanthate (NEN) and norethisterone acetate (NET).","6786825",42]
["Okadaic Acid","Okadaic Acid","D019319","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1999,"10786819","Effect of okadaic acid and calyculin-A, two protein phosphatase inhibitors, on thyrotropin-stimulated triiodothyronine secretion in cultured sheep thyroid cells.","10786819",42]
["Peanut Oil","Peanut Oil","D000074241","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2006,"17093176","Efficacy of oral iodized peanut oil is greater than that of iodized poppy seed oil among Indonesian schoolchildren.","17093176",42]
["Pentobarbital","Pentobarbital","D010424","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1965,"4158624","Pentobarbitone-barbitone anaesthesia and thyroid function in the rat..","4158624",42]
["perchlorate","perchlorate","C494474","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2008,"18275962","A perchlorate sensitive iodide transporter in frogs.","18275962",42]
["perfluorooctane sulfonic acid","perfluorooctane sulfonic acid","C076994","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2012,"22453676","Thyroid function and perfluoroalkyl acids in children living near a chemical plant.","22453676",42]
["Phenobarbital","Phenobarbital","D010634","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1999,"10036213","Phenobarbital, beta-naphthoflavone, clofibrate, and pregnenolone-16alpha-carbonitrile do not affect hepatic thyroid hormone UDP-glucuronosyl transferase activity, and thyroid gland function in mice.","10036213",42]
["Phenobarbital","Phenobarbital","D010634","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1984,"6593988","Effects of phenobarbital, diphenylhydantoin and carbamazepine on thyroid function in epileptic children.","6593988",42]
["Phenylbutazone","Phenylbutazone","D010653","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1957,"13406001","The effect of phenylbutazone and a related analogue (G25671) upon thyroid function.","13406001",42]
["Phloretin","Phloretin","D010693","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1985,"2990874","Polyphloretin phosphate, an antagonist of thyrotropin action: evidence for an interaction with the hormone rather than the receptor.","2990874",42]
["Polytetrafluoroethylene","Polytetrafluoroethylene","D011138","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2006,"16896756","Voice quality improvement after management of unilateral vocal cord paralysis with different techniques.","16896756",42]
["Potassium Iodide","Potassium Iodide","D011193","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1975,"1208204","Comparison of various treatment schedules for accelerating the elimination of radioiodine from the thyroid and the human body.","1208204",42]
["Potassium Iodide","Potassium Iodide","D011193","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2008,"19054795","Thyroid dose estimation with potassium iodide (KI) administration in a nuclear emergency.","19054795",42]
["Potassium Iodide","Potassium Iodide","D011193","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1994,"8075176","125I-fibrinogen: thyroid blocking with 2.5 mg potassium iodide twice daily in patients after hip surgery.","8075176",42]
["potassium perchlorate","potassium perchlorate","C009006","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1983,"6302362","Altered anion handling by choroid plexus in renal insufficiency.","6302362",42]
["Povidone","Povidone","D011205","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1987,"3572688","The use of povidone iodine in neonatal bowel surgery.","3572688",42]
["Povidone-Iodine","Povidone-Iodine","D011206","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1997,"9250480","125I uptake competing with iodine absorption by the thyroid gland following povidone-iodine skin application.","9250480",42]
["Propranolol","Propranolol","D011433","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1975,"1175309","The influence of preoperative drug treatment on the histological appearances and in vitro 131I uptake of human hyperplastic thyroid gland.","1175309",42]
["Propranolol","Propranolol","D011433","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1970,"4316489","Effects of epinephrine on iodine and intermediary metabolism in isolated thyroid cells.","4316489",42]
["Propylthiouracil","Propylthiouracil","D011441","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1954,"13177681","Effect of pretreatment with propyl thiouracil on accumulation of astatine211 by thyroid gland of the rat.","13177681",42]
["Propylthiouracil","Propylthiouracil","D011441","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1956,"13344413","Radioiodine not dischargeable with perchlorate in the thyroids of propylthiouracil treated rats.","13344413",42]
["Propylthiouracil","Propylthiouracil","D011441","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1962,"14477164","Effect of propylthiouracil and thyroid-stimulating hormone on glucose oxidation in rat thyroid tissue.","14477164",42]
["Propylthiouracil","Propylthiouracil","D011441","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1948,"18905442","Propylthiouracil and methyl thiouracil in the treatment of hyperthyroidism.","18905442",42]
["Propylthiouracil","Propylthiouracil","D011441","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2012,"22342233","Thyroid organotypic rat and human cultures used to investigate drug effects on thyroid function, hormone synthesis and release pathways.","22342233",42]
["Propylthiouracil","Propylthiouracil","D011441","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1973,"4771360","Reactivity of the pituitary-thyroid system to exogenic thyroxine and propylthiouracil during the peri- and neonatal period in the rabbit.","4771360",42]
["Propylthiouracil","Propylthiouracil","D011441","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1966,"5921765","Evaluation of the peripheral deiodination of L-thyroxine as an index of its thyrotrophin suppressing effectiveness.","5921765",42]
["Propylthiouracil","Propylthiouracil","D011441","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1983,"6872960","Propylthiouracil (PTU) pharmacology in the rat. I. Serum and thyroid PTU measurements by radioimmunoassay.","6872960",42]
["prostaglandin F2beta","prostaglandin F2beta","C037027","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1983,"6605275","Role of the adrenal cortex in gastric mucosal protection by prostaglandins, sulfhydryls, and cimetidine in the rat.","6605275",42]
["pyrimidine","pyrimidine","C030986","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1945,"21004429","Antithyroid studies; the goitrogenic activity of some thioureas, pyrimidines and miscellaneous compounds.","21004429",42]
["Radioactive Fallout","Radioactive Fallout","D011847","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1962,"13889684","Iodine-131 dose from Soviet nuclear tests. Accumulation of iodine-131 in human thyroids was observed by in vivo procedures during the 1961 tests.","13889684",42]
["Radioactive Fallout","Radioactive Fallout","D011847","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1967,"5187190","Environmental radioactivity in New Zealand and results of extended monitoring of fallout from French nuclear tests in the Pacific. HASL-182.","5187190",42]
["Reserpine","Reserpine","D012110","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1966,"5984944","[Karyometric findings in the thyroid of rats treated with reserpine].","5984944",42]
["Rose Bengal","Rose Bengal","D012395","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1986,"3459920","Induction of thyroid tumors in (C57BL/6N x C3H/N)F1 mice by oral administration of 9-3',4',5',6'-tetrachloro-o-carboxy phenyl-6-hydroxy-2,4,5,7-tetraiodo-3-isoxanthone sodium (Food Red 105, rose bengal B).","3459920",42]
["Serotonin","Serotonin","D012701","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1975,"1183406","Influence of histamine- and 5-hydroxytryptamine-containing thyroid mast cells on thyroid blood flow and permeability in the rat.","1183406",42]
["Serotonin","Serotonin","D012701","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1960,"14429627","The effect of methimazole and potassium thiocyanate on the 5-hydroxytryptamine content of the rat thyroid gland.","14429627",42]
["Sewage","Sewage","D012722","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1990,"2323925","Radionuclide uptake and growth of barn swallows nesting by radioactive leaching ponds.","2323925",42]
["sodium bromide","sodium bromide","C027938","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1993,"8094973","The no-effect level of sodium bromide in healthy volunteers.","8094973",42]
["Sodium Chloride","Sodium Chloride","D012965","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1977,"892411","[Hypophyseal and thyroidal modifications in Pleurodeles in saline].","892411",42]
["Sodium Chloride, Dietary","Sodium Chloride, Dietary","D017673","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2012,"22816208","Current status of iodine intake in Croatia--the results of 2009 survey.","22816208",42]
["Sodium Iodide","Sodium Iodide","D012974","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1983,"6131171","Reactor accidents: iodine supplements?","6131171",42]
["sodium perchlorate","sodium perchlorate","C031068","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1989,"2555140","Preservation of sodium-dependent iodide transport activity by methimazole and mercaptoethanol in phospholipid vesicles containing thyroid plasma membranes: with evidence of difference in the action of perchlorate and thiocyanate.","2555140",42]
["Sodium Pertechnetate Tc 99m","Sodium Pertechnetate Tc 99m","D013670","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2002,"12425892","[Lung accumulation of 99mTc-pertechnetate in thyroid scintigraphy].","12425892",42]
["Sodium Pertechnetate Tc 99m","Sodium Pertechnetate Tc 99m","D013670","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2013,"23843083","Small-animal radionuclide luminescence imaging of thyroid and salivary glands with Tc99m-pertechnetate.","23843083",42]
["Sodium, Dietary","Sodium, Dietary","D012982","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1988,"3054267","Thyroid volume of East Slovakian adolescents determined by ultrasound 40 years after the introduction of iodized salt.","3054267",42]
["Sphingosine","Sphingosine","D013110","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2013,"23467817","Fiber specific changes in sphingolipid metabolism in skeletal muscles of hyperthyroid rats.","23467817",42]
["Succimer","Succimer","D004113","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1990,"2155729","Spindle cell sarcoma showing concentration of Tc-99m sodium pertechnetate and Tc-99m (V) DMSA.","2155729",42]
["Sulfamethoxazole","Sulfamethoxazole","D013420","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1982,"6123827","Co-trimoxazole and the thyroid.","6123827",42]
["Taurine","Taurine","D013654","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1993,"8382624","Cloning of the human taurine transporter and characterization of taurine uptake in thyroid cells.","8382624",42]
["Technetium Tc 99m Sestamibi","Technetium Tc 99m Sestamibi","D017256","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,2004,"15041979","Is thyroid suppression an effective procedure in improving preoperative sestamibi parathyroid scintigraphy?","15041979",42]
["Technetium Tc 99m Sestamibi","Technetium Tc 99m Sestamibi","D017256","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1997,"9193822","Double-phase scanning of the thyroid gland with Tc-99m MIBI in a patient with a malignant nodule. A case of tracer redistribution?","9193822",42]
["Tetradecanoylphorbol Acetate","Tetradecanoylphorbol Acetate","D013755","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1994,"8021301","Differential expression of thrombospondin, collagen, and thyroglobulin by thyroid-stimulating hormone and tumor-promoting phorbol ester in cultured porcine thyroid cells.","8021301",42]
["Theophylline","Theophylline","D013806","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1967,"6027410","Effects of theophylline on the serum calcium of rats after parathyroidectomy and administration of parathyroid hormone.","6027410",42]
["thiazosulfone","thiazosulfone","C009453","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1947,"20290683","Promizole treatment of miliary tuberculosis; toxic effects on thyroid gland and maturation.","20290683",42]
["thiocyanate","thiocyanate","C031760","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2005,"15572417","The effect of perchlorate, thiocyanate, and nitrate on thyroid function in workers exposed to perchlorate long-term.","15572417",42]
["Thiouracil","Thiouracil","D013889","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,1957,"13439093","Growth in the cell populations of the thyroid gland of rats treated with thiouracil.","13439093",42]
["Thiouracil","Thiouracil","D013889","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1947,"20285374","Preoperative management of hyperthyroidism; use of thiouracil and thiobarbital.","20285374",42]
["Thiouracil","Thiouracil","D013889","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1965,"14332615","COMPARISON OF THE EFFECTS OF THIOURACIL, PROPYLTHIOURACIL, AND METHIMAZOLE ON I-131 METABOLISM BY THE CHICK THYROID AND MEASUREMENTS OT THYROXINE SECRETION RATES.","14332615",42]
["Thiouracil","Thiouracil","D013889","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1948,"18122607","[Not Available].","18122607",42]
["Thiouracil","Thiouracil","D013889","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1946,"20274029","Propyl thiouracil in the treatment of hyperthyroidism.","20274029",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C95427,B95427)","v":"Thiouracil"},"Thiouracil","D013889","1_MIE",279,1,"Thyroperoxidase","Inhibition",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J95427,K95427)","v":"Thyroid Gland"},"D013961","Thyroid Gland",1,1,1946,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q95427,Q95427)","v":"20984890"},"The use of thiouracil in thyroid surgery.","20984890",42]
["Thiouracil","Thiouracil","D013889","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1946,"21016694","The present status of thiouracil in preparing thyrotoxic patients for surgery.","21016694",42]
["Thiourea","Thiourea","D013890","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1961,"13771347","Failure of thiourea to prevent hormone synthesis by the thyroid gland of man and animals treated with thyrotropin.","13771347",42]
["Thiourea","Thiourea","D013890","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1949,"15392352","[Effect of ethylurethane on the histologic activation of the thyroid gland by methylthiouracil].","15392352",42]
["Thiourea","Thiourea","D013890","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1949,"18151719","The absorption spectra and ionic dissociation of thiouracil derivatives with reference to their anti-thyroid activity.","18151719",42]
["Thiourea","Thiourea","D013890","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1945,"21006053","Treatment of hyperthyroidism with a combination of iodine, thiourea in small doses, and desiccated thyroid.","21006053",42]
["tranilast","tranilast","C012293","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1988,"2463963","Inhibition of free triiodothyronine release from mouse thyroid lobes by N-(3',4'-dimethoxycinnamoyl)anthranilic acid (tranilast).","2463963",42]
["tributyltin","tributyltin","C011559","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2014,"25101840","Disruption of thyroid hormone functions by low dose exposure of tributyltin: an in vitro and in vivo approach.","25101840",42]
["Trimethoprim, Sulfamethoxazole Drug Combination","Trimethoprim, Sulfamethoxazole Drug Combination","D015662","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2002,"12322917","Effects of short-term trimethoprim-sulfamethoxazole administration on thyroid function in dogs.","12322917",42]
["Trypan Blue","Trypan Blue","D014343","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1970,"5456644","Influence of age and sex on chronic thyroiditis in rats given subcutaneous injections of trypan blue.","5456644",42]
["Vitamin A","Vitamin A","D014801","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2001,"11563543","Effects of retinoids on porcine thyrocytes under different culture conditions.","11563543",42]
["Vitamin A","Vitamin A","D014801","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1964,"14289765","FACTORS AFFECTING THE ABSORPTION OF CAROTENE AND ITS CONVERSION INTO VITAMIN A.","14289765",42]
["Vitamin A","Vitamin A","D014801","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1968,"5656701","Influence of different forms of vitamin A, thyroxine, and thiouracil on carotenoid utilization by chicks.","5656701",42]
["Vitamin B 12","Vitamin B 12","D014805","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1950,"15435495","The ability of liver preparations and vitamin B12 to maintain thymus weight in thyroid-fed rats having greatly hypertrophied adrenal glands.","15435495",42]
["Vitamin E","Vitamin E","D014810","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2003,"14677760","Effect of vitamin E on follicular cell proliferation and expression of apoptosis-associated factors in rats with 6-N-propyl-2-thiouracil-induced goitrogenesis.","14677760",42]
["VX","VX","C009680","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,3,2008,"18614271","An animal model to study health effects during continuous low-dose exposure to the nerve agent VX.","18614271",42]
["Water","Water","D014867","1_MIE",279,1,"Thyroperoxidase","Inhibition","Thyroid Gland","D013961","Thyroid Gland",1,1,1971,"5115548","Organ weights and water composition of the New Zealand albino rabbit (Oryctalagus cuniculus).","5115548",42]
["2,2',4,4',5-brominated diphenyl ether","2,2',4,4',5-brominated diphenyl ether","C477694","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2017,"28006665","Alteration of thyroid hormone concentrations in juvenile Chinook salmon (Oncorhynchus tshawytscha) exposed to polybrominated diphenyl ethers, BDE-47 and BDE-99.","28006665",42]
["2,4,5,2',4',5'-hexachlorobiphenyl","2,4,5,2',4',5'-hexachlorobiphenyl","C014024","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1993,"8516785","Effects of perinatal exposure to specific PCB congeners on thyroid hormone concentrations and thyroid histology in the rat.","8516785",42]
["2-methylimidazole","2-methylimidazole","C032655","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2008,"17924096","Induction of thyroid and liver tumors by chronic exposure to 2-methylimidazole in F344/N rats and B6C3F1 mice.","17924096",42]
["5-Methoxytryptamine","5-Methoxytryptamine","D008735","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1997,"9376758","[The effect of melatonin and mexamine on the human thyroid under in-vitro conditions].","9376758",42]
["Aminopyrine","Aminopyrine","D000632","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1975,"52883","Drug-induced agranulocytosis. A survey of twenty-three episodes.","52883",42]
["Amiodarone","Amiodarone","D000638","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2003,"14655464","[Amiodarone-induced thyrotoxicosis: case report and review of the literature].","14655464",42]
["Amiodarone","Amiodarone","D000638","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2012,"23240319","[Amiodarone and thyroid].","23240319",42]
["Amiodarone","Amiodarone","D000638","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1996,"8946449","Amiodarone induced hyperthyroidism: a case series and brief review of literature.","8946449",42]
["Amphetamine","Amphetamine","D000661","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1972,"4629314","Mortality rate in patients receiving \"diet pills\".","4629314",42]
["Ascorbic Acid","Ascorbic Acid","D001205","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1965,"5872952","[Effect of thyroidine on distribution of ascorbic acid in radiation injuries].","5872952",42]
["Aurothioglucose","Aurothioglucose","D006051","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1989,"2496911","Attenuated response to cold of brown adipose tissue of mice made obese with gold thioglucose.","2496911",42]
["beta-Naphthoflavone","beta-Naphthoflavone","D019324","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2005,"15712285","Physiological and genetic responses of European eel (Anguilla anguilla L.) to short-term chromium or copper exposure-Influence of preexposure to a PAH-like compound.","15712285",42]
["Blood Glucose","Blood Glucose","D001786","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1983,"6357985","Hormonal profile and glucose tolerance in late pregnancy and postpartum.","6357985",42]
["Blood Glucose","Blood Glucose","D001786","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1995,"7730983","The effects of thyroid hormones on oxygen and glucose metabolism in the sheep fetus during late gestation.","7730983",42]
["Capsaicin","Capsaicin","D002211","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2001,"11239999","Adaptation to capsaicin burn: effects of concentration and individual differences.","11239999",42]
["Carbimazole","Carbimazole","D002231","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1963,"13936246","Treatment of angina pectoris with antithyroid drug (Carbimazole).","13936246",42]
["Carbimazole","Carbimazole","D002231","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2008,"18528187","Long-term carbimazole intake does not affect success rate of radioactive 131Iodine in treatment of Graves' hyperthyroidism.","18528187",42]
["Carbimazole","Carbimazole","D002231","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2014,"24255992","Carbimazole-associated hypersensitivity vasculitis in a cat.","24255992",42]
["Carbimazole","Carbimazole","D002231","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1978,"86350","Low dose lithium-carbimazole in the treatment of thyrotoxicosis.","86350",42]
["Chlorodiphenyl (54% Chlorine)","Chlorodiphenyl (54% Chlorine)","D020111","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2002,"12417482","Polychlorinated biphenyls alter extraneuronal but not tissue dopamine concentrations in adult rat striatum: an in vivo microdialysis study.","12417482",42]
["Chlorodiphenyl (54% Chlorine)","Chlorodiphenyl (54% Chlorine)","D020111","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2016,"26561944","Effects of embryonic exposure to polychlorinated biphenyls (PCBs) on larval zebrafish behavior.","26561944",42]
["Cholesterol","Cholesterol","D002784","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1959,"13666722","[Cholesterol pericarditis of hypothyroid origin; recovery through delta-cortisone after failure with thyroid treatment].","13666722",42]
["Cholesterol","Cholesterol","D002784","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1965,"14261403","THYROID INDICES DURING REPLACEMENT WITH DESICCATED THYROID AND PROLOID.","14261403",42]
["Cholesterol","Cholesterol","D002784","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1981,"6178582","Alterations in serum HDL and LDL cholesterol during antithyroid treatment.","6178582",42]
["ciprofibrate","ciprofibrate","C019304","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1993,"8471068","Role of thyroid state on induction by ciprofibrate of laurate hydroxylase and peroxisomal enzymes in rat liver microsomes.","8471068",42]
["coenzyme Q10","coenzyme Q10","C024989","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2011,"22272129","Hormonal influence on coenzyme Q(10) levels in blood plasma.","22272129",42]
["dechlorane plus","dechlorane plus","C526360","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2016,"26735721","Toxicological responses following short-term exposure through gavage feeding or water-borne exposure to Dechlorane Plus in zebrafish (Danio rerio).","26735721",42]
["Dexamethasone","Dexamethasone","D003907","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2009,"19850691","Prevention of relapse of Graves' disease by treatment with an intrathyroid injection of dexamethasone.","19850691",42]
["Diatrizoate Meglumine","Diatrizoate Meglumine","D003974","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1983,"6682783","The effect of iodine containing contrast medium on thyroid function of patients undergoing coronary angiography.","6682783",42]
["Diethylstilbestrol","Diethylstilbestrol","D004054","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1962,"13989203","Changes in utilization of thyroid hormone and thyroxine distribution space in sheep treated with stilboestrol.","13989203",42]
["Dopamine","Dopamine","D004298","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1980,"7400302","Prolonged dopamine administration and thyroid hormone economy in normal and critically ill subjects.","7400302",42]
["Edetic Acid","Edetic Acid","D004492","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1968,"4971425","Serum calcium homeostasis in radioiodine treated thyrotoxic subjects as measured by ethylenediamine tetra-acetate infusion.","4971425",42]
["Epinephrine","Epinephrine","D004837","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2011,"21482272","A peroxidase-based method for the determination of dopamine, adrenaline, and α-methyldopa in the presence of thyroid hormones in pharmaceutical forms.","21482272",42]
["Ethanol","Ethanol","D000431","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1992,"1413849","Percutaneous ethanol injection treatment of autonomously functioning single thyroid nodules: optimization of treatment and short term outcome.","1413849",42]
["Etretinate","Etretinate","D005050","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1985,"4091153","[Effects of administration of moderate doses of etretinate (RO 10-9359) on rats deficient in vitamin A].","4091153",42]
["Fluoxetine","Fluoxetine","D005473","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2010,"19835665","The thyroid hormone, triiodothyronine, enhances fluoxetine-induced neurogenesis in rats: possible role in antidepressant-augmenting properties.","19835665",42]
["Furosemide","Furosemide","D005665","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2005,"15805713","Severe starvation hypoglycemia and congestive heart failure induced by thyroid crisis, with accidentally induced severe liver dysfunction and disseminated intravascular coagulation.","15805713",42]
["Glucose","Glucose","D005947","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1964,"14253314","[BIOSYNTHESIS OF THYROID HORMONE: ON THE MECHANISM OF THE IODINATION REACTION IN THE THYROID GLAND].","14253314",42]
["Glycogen","Glycogen","D006003","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2003,"12759768","Changes in glucose, glycogen, thyroid activity and hypothalamic catecholamines in tench by starvation and refeeding.","12759768",42]
["Gold Sodium Thiomalate","Gold Sodium Thiomalate","D006052","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1995,"7647570","Prospective studies of thyroid function in patients receiving gold therapy.","7647570",42]
["hexabromocyclododecane","hexabromocyclododecane","C089796","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2014,"25693409","[Correlations between HBCD and thyroid hormone concentrations in human serum from production source area].","25693409",42]
["Imipramine","Imipramine","D007099","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2009,"19340585","Chronic administration of imipramine normalizes decreased sexual motivation and increased predisposition to catalepsy induced by propylthiouracil in rats.","19340585",42]
["iodothiouracil","iodothiouracil","C036667","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1952,"14916878","The effect of iodothiouracil on the biologic decay of thyroidal radio iodine.","14916878",42]
["Ipodate","Ipodate","D007487","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1989,"2613192","Sodium ipodate in the preparation of Graves' hyperthyroid patients for thyroidectomy.","2613192",42]
["kojic acid","kojic acid","C011890","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1999,"10426808","Changes in thyroid function during development of thyroid hyperplasia induced by kojic acid in F344 rats.","10426808",42]
["Malondialdehyde","Malondialdehyde","D008315","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2015,"25843331","Ischemia-modified albümin and malondialdehyde levels in patients with overt and subclinical hyperthyroidism: effects of treatment on oxidative stress.","25843331",42]
["Methandrostenolone","Methandrostenolone","D008696","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1963,"14100279","HYDROXYPROLINE EXCRETION IN ENDOCRINE DISEASE.","14100279",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2000,"10668818","Prothrombin, activated partial thromboplastin, and proteins induced by vitamin K absence or antagonists clotting times in 20 hyperthyroid cats before and after methimazole treatment.","10668818",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2002,"12081614","Bioavailability of transdermal methimazole in a pluronic lecithin organogel (PLO) in healthy cats.","12081614",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2016,"27075316","[Hyperthyroid and acute tonsillitis in a 23-year-old woman].","27075316",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2004,"15274789","[Methimazole hepatitis].","15274789",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2005,"16358088","[Cost-effectiveness of the clinical treatment of Grave's disease in a public University Hospital: a retrospective analysis and prospective projection for a therapeutic approach].","16358088",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2009,"19445623","Methimazole-induced agranulocytosis in patients with Graves' disease is more frequent with an initial dose of 30 mg daily than with 15 mg daily.","19445623",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2010,"20701025","[Pharmacokinetics of digoxin in hyperthyroidism. Effect of methimazole].","20701025",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2013,"22991925","Expression of prostanoid receptors (EP1, 2, 3, and 4) in normal and methimazole-treated mouse olfactory epithelium.","22991925",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2014,"24174499","Transdermal application of methimazole in hyperthyroid cats: a long-term follow-up study.","24174499",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2017,"28781323","Familial Dysalbuminemic Hyperthyroxinemia that was Inappropriately Treated with Thiamazole Due to Pseudo-thyrotoxic Symptoms.","28781323",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1995,"7586593","Response to methimazole in Graves' disease. The European Multicenter Study Group.","7586593",42]
["Methimazole","Methimazole","D008713","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1997,"9080924","Elevation of serum creatine kinase during treatment with antithyroid drugs in patients with hyperthyroidism due to Graves disease. A novel side effect of antithyroid drugs.","9080924",42]
["Methoxyhydroxyphenylglycol","Methoxyhydroxyphenylglycol","D008734","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1991,"1864254","[Plasma MHPG, peripheral noradrenergic marker and hormonal plasma levels of cortisol-T3-T4-TSH in depressive syndromes].","1864254",42]
["Methylthiouracil","Methylthiouracil","D008779","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1970,"4108405","[Thyroid gland reactions following administration of NaCl, methylthiouracil, diiodotyrosine, p-hydroxypropiophenone and alloxan separately and in combination].","4108405",42]
["Mevalonic Acid","Mevalonic Acid","D008798","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1964,"14244940","EFFECTS OF HYPOPHYSECTOMY, THYROIDECTOMY AND THYROID HORMONES ON STEROID METABOLISM IN THE RAT.","14244940",42]
["mustard oil","mustard oil","C027793","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1964,"14212479","ON THE POSSIBLE MECHANISM OF THE ANTITHYROIDAL ACTION  OF SOME NATURAL MUSTARD OILS.","14212479",42]
["Nimodipine","Nimodipine","D009553","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2001,"11707158","Rapid cycling bipolar disease: new concepts and treatments.","11707158",42]
["Norepinephrine","Norepinephrine","D009638","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1980,"7419674","Normal levels of norepinephrine in short term hypothyroidism.","7419674",42]
["Oleanolic Acid","Oleanolic Acid","D009828","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2014,"24626155","Oleanolic acid suppresses aerobic glycolysis in cancer cells by switching pyruvate kinase type M isoforms.","24626155",42]
["p-Aminohippuric Acid","p-Aminohippuric Acid","D010130","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1987,"3632649","Transport of p-aminohippurate in renal cortical slices of rats of different ages following treatment with thyroid hormones.","3632649",42]
["Pentobarbital","Pentobarbital","D010424","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1966,"4381001","Paradoxical effect of dichloroisoproterenol on pentobarbital sleep time in hyperthyroid mice.","4381001",42]
["perfluorooctane sulfonic acid","perfluorooctane sulfonic acid","C076994","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2012,"22453676","Thyroid function and perfluoroalkyl acids in children living near a chemical plant.","22453676",42]
["Phenobarbital","Phenobarbital","D010634","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1964,"14137651","OLD AND STILL GOOD.","14137651",42]
["Phenylbutazone","Phenylbutazone","D010653","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1971,"4105253","[Agranulocytosis caused by medication].","4105253",42]
["Potassium Iodide","Potassium Iodide","D011193","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1965,"4158239","Influence of iodine intake after treatment with antithyroid drugs.","4158239",42]
["Povidone","Povidone","D011205","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1985,"2860161","The influence of povidone-iodine treatment on thyroid hormones in severe burns.","2860161",42]
["Prednisolone","Prednisolone","D011239","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1967,"6045048","The effect of hormones in experimental aplastic anaemia in rats.","6045048",42]
["Prednisone","Prednisone","D011241","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1980,"7424570","Thyrotoxic hypercalcemia treated with corticosteroids.","7424570",42]
["Propranolol","Propranolol","D011433","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1984,"6148879","A comparison of propranolol and nadolol pharmacokinetics and clinical effects in thyrotoxicosis.","6148879",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1999,"10583195","Propylthiouracil-induced antineutrophil cytoplasmic antibodies in a patient with Graves' disease and a neutrophilic dermatosis.","10583195",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2001,"11852352","[Propythiouracil and perchlorate effects on thyroid function in young and lactating mice].","11852352",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1964,"14217677","AMYLOIDOSIS IN C3H MICE TREATED WITH GOITROGENS.","14217677",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2004,"15356044","Propylthiouracil before 131I therapy of hyperthyroid diseases: effect on cure rate evaluated by a randomized clinical trial.","15356044",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2006,"16758084","[Antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis associated to the use of propylthiouracil. Report of four cases].","16758084",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2007,"17957924","Treatment outcome of Graves' disease in Thai children.","17957924",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2010,"19851036","A long-term follow-up of serum myeloperoxidase antineutrophil cytoplasmic antibodies (MPO-ANCA) in patients with Graves disease treated with propylthiouracil.","19851036",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2012,"22632530","Successful treatment of thyrotoxic crisis after esophagectomy in an elderly woman with hyperthyroidism.","22632530",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2015,"26603813","Hyperthyroidism and propylthiouracil-induced liver failure in pregnancy.","26603813",42]
["Propylthiouracil","Propylthiouracil","D011441","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1979,"421132","Sequential effects of thyroxine on the developing cerebellum of rats made hypothyroid by propylthiouracil.","421132",42]
["pseurotin","pseurotin","C012013","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2017,"28641457","Antiglioma pseurotin A from marine Bacillus sp. FS8D regulating tumour metabolic enzymes.","28641457",42]
["Reserpine","Reserpine","D012110","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1954,"13175419","[Reserpine as thyroxine antagonist].","13175419",42]
["Riboflavin","Riboflavin","D012256","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2004,"15447919","Phenotypic expression of the methylenetetrahydrofolate reductase 677C--&gt;T polymorphism and flavin cofactor availability in thyroid dysfunction.","15447919",42]
["sapropterin","sapropterin","C003402","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,2000,"11094150","2-thiouracil is a selective inhibitor of neuronal nitric oxide synthase antagonising tetrahydrobiopterin-dependent enzyme activation and dimerisation.","11094150",42]
["Sodium Chloride, Dietary","Sodium Chloride, Dietary","D017673","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2017,"28103777","Role of Iodine in Metabolism.","28103777",42]
["sodium perchlorate","sodium perchlorate","C031068","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1981,"6276239","[Subclinical hypothyroidism associated with the positive perchlorate discharge test in aged subjects (author's transl)].","6276239",42]
["Spironolactone","Spironolactone","D013148","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1983,"6430208","[Spironolactone in idiopathic hirsutism, clinical and biological evaluation of treatment].","6430208",42]
["Taurine","Taurine","D013654","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1969,"4302277","Cholelithiasis in rabbits: effects of bile constituents and hormones on dissolution of gallstones.","4302277",42]
["Thiamine Pyrophosphate","Thiamine Pyrophosphate","D013835","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1974,"4479696","[Changes in some indices of carbohydrate metabolism, cortisol metabolism, and the level of thyroid hormones under the effects of cocarboxylase in patients with toxic goiter].","4479696",42]
["Thiouracil","Thiouracil","D013889","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1963,"14010871","Effect of potassium iodide and duodenal powder on the growth and organ weights of goitrogenfed rats.","14010871",42]
["Thiouracil","Thiouracil","D013889","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1951,"14897921","The determination of propylthiouracil in urine with 2:6-dichloro-quinonechloroimide.","14897921",42]
["Tolbutamide","Tolbutamide","D014044","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1964,"14129881","FETAL AND NEONATAL HAZARDS FROM DRUGS ADMINISTERED DURING PREGNANCY.","14129881",42]
["triadimefon","triadimefon","C032910","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2006,"17178689","Transcriptional profiles in liver from rats treated with tumorigenic and non-tumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil.","17178689",42]
["trifluoroiodomethane","trifluoroiodomethane","C105057","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,1999,"10562696","Reproductive toxicity screen of trifluoroiodomethane (CF(3)I) in Sprague-Dawley rats.","10562696",42]
["Urea","Urea","D014508","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,2,1963,"14087884","QUININE DIMORPHISM: A CARDINAL DETERMINANT OF TASTE SENSITIVITY.","14087884",42]
["Vitamin B 6","Vitamin B 6","D025101","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2014,"24738179","[Basic pathogenesis of, heterogeneity of , and its therapeutic strategy for West syndrome and tuberous sclerosis complex].","24738179",42]
["Vitamin E","Vitamin E","D014810","2_KE",277,2,"Thyroid hormone synthesis","Decreased","Thyroid Hormones","D013963","Thyroid Hormones",1,1,2004,"15748470","[Influence of oral sodium selenite and vitamin E on thyroid hormones in patients with cardiovascular disease at altitude].","15748470",42]
["1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine","D019307","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1990,"2103931","[Calmodulin dependent regulation of smooth muscle contraction].","2103931",42]
["2,3-dihydroxypyridine","2,3-dihydroxypyridine","C035877","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1994,"8157525","Blood metabolite and regulatory hormone concentrations and response to metabolic challenges during the infusion of mimosine and 2,3-dihydroxypyridine in alpine goats.","8157525",42]
["25-hydroxyvitamin D","25-hydroxyvitamin D","C104450","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2007,"17849744","Prevalence of vitamin D insufficiency in obese children and adolescents.","17849744",42]
["3,4,5,3',4'-pentachlorobiphenyl","3,4,5,3',4'-pentachlorobiphenyl","C023035","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2009,"19429246","Effects of 3,3',4,4',5-pentachlorobiphenyl (PCB126) on vertebral bone mineralization and on thyroxin and vitamin D levels in Sprague-Dawley rats.","19429246",42]
["4,4'-methylenebis(N,N'-dimethyl)aniline","4,4'-methylenebis(N,N'-dimethyl)aniline","C574620","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"22712849","Subchronic thyroid toxicity evaluation of 4,4'-methylenebis(N,N'-dimethyl)aniline in Fischer 344 rats.","22712849",42]
["9,10-Dimethyl-1,2-benzanthracene","9,10-Dimethyl-1,2-benzanthracene","D015127","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1978,"99748","The effect of altered thyroid state on prolactin binding to liver and 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.","99748",42]
["Alloxan","Alloxan","D000496","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"5951905","Effect of thyroid hormones, somatotrophin, insulin and corticosteroids on synthesis of collagen in granulation tissue both in vivo and in vitro.","5951905",42]
["Aminosalicylic Acid","Aminosalicylic Acid","D010131","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14219696","[EXPERIMENTAL AND CLINICAL STUDIES ON THE INFLUENCE OF BETA-GLUCURONIDASE INHIBITOR ON THE LIVING BODY].","14219696",42]
["Amiodarone","Amiodarone","D000638","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"1789065","Amiodarone and thyroid hormone metabolism in the rat heart.","1789065",42]
["Amiodarone","Amiodarone","D000638","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"3923304","Amiodarone. The dilemma of hyperthyroxinaemia and the treatment of thyrotoxicosis.","3923304",42]
["Amiodarone","Amiodarone","D000638","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1983,"6617581","The effects of amiodarone on serum thyroid hormones and hepatic thyroxine 5'-monodeiodination in rats.","6617581",42]
["ammonium perchlorate","ammonium perchlorate","C053506","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"25318876","Change of iodine load and thyroid homeostasis induced by ammonium perchlorate in rats.","25318876",42]
["Arecoline","Arecoline","D001115","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"3406243","Cholinergic REM sleep induction by arecoline in normal subjects: relation to thyroid function.","3406243",42]
["Azoxymethane","Azoxymethane","D001397","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1992,"1555896","Enhancement by thyroxine of experimental carcinogenesis induced in rat colon by azoxymethane.","1555896",42]
["beta Carotene","beta Carotene","D019207","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"3937314","[Concentrations of thyroxine, beta carotene, vitamin A and pregnancy in heifers after administration of beta carotene].","3937314",42]
["bexarotene","bexarotene","C095105","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2016,"26688184","[Thyroid and lipidic dysfunction associated with bexarotene in cutaneous T-cell lymphoma].","26688184",42]
["bisphenol A","bisphenol A","C006780","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2005,"16294924","Effects of in utero and lactational exposure to bisphenol A on thyroid status in F1 rat offspring.","16294924",42]
["Blood Glucose","Blood Glucose","D001786","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"3517902","Ovarian hormone effects on activity, glucoregulation and thyroid hormones in the rat.","3517902",42]
["Blood Glucose","Blood Glucose","D001786","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1977,"604183","Serum hormones in the perinatal pig and the effect of exogenous insulin on blood sugars.","604183",42]
["Bromocriptine","Bromocriptine","D001971","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"3926809","Growth enhancement by dopaminergic therapy in children with intrauterine growth retardation.","3926809",42]
["calcium glubionate","calcium glubionate","C042131","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"2994578","Impetigo herpetiformis and hypoparathyroidism.","2994578",42]
["Carbamazepine","Carbamazepine","D002220","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"2870442","Relationship between cerebrospinal fluid somatostatin and peripheral thyroid hormones with carbamazepine treatment.","2870442",42]
["Carbimazole","Carbimazole","D002231","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1979,"117739","[Serum thyroid hormones and TSH response to TRH during treatment of Graves' disease by carbimazole (author's transl)].","117739",42]
["Carbimazole","Carbimazole","D002231","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"7234286","Treatment of maternal hyperthyroidism with antithyroid agents and changes in thyrotrophin and thyroxine in the newborn.","7234286",42]
["catechol","catechol","C034221","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"13954138","Effect of various compounds on the binding of thyroxine to serum proteins in the rat.","13954138",42]
["Chlorhexidine","Chlorhexidine","D002710","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1997,"9329422","Topical iodine-containing antiseptics and subclinical hypothyroidism in preterm infants.","9329422",42]
["Chlorpromazine","Chlorpromazine","D002746","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"5718529","Action of chlorpromazine in normal, thyroxine treated and cold acclimated rats.","5718529",42]
["Cholesterol","Cholesterol","D002784","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1961,"13888425","Tissue distribution of thyroxin analogues and their effects on cholesterol metabolism.","13888425",42]
["Cholesterol","Cholesterol","D002784","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1961,"14497963","The reduction of serum cholesterol with thyroid analogues. II. The reduction of serum cholesterol by dextro-thyroxine in hypercholesterolemic patients with coronary heart disease.","14497963",42]
["Cholesterol","Cholesterol","D002784","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28625503","Thyroid Hormone Status in Sitosterolemia Is Modified by Ezetimibe.","28625503",42]
["Cholesterol","Cholesterol","D002784","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"4888371","[Importance of lipids in various metabolic aspects. 3. Regulation role of bile acids in the metabolism of cholesterol].","4888371",42]
["Cholesterol","Cholesterol","D002784","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"5632296","[Experimental comparative studies in animals on the effect of D-thyroxine and D-triiodothyronine in alimentarily disturbed lipid metabolism].","5632296",42]
["Chondroitin","Chondroitin","D002807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1961,"13712342","[Changes in connective tissue metabolism by toxic, infectious and allergic influences].","13712342",42]
["clobazam","clobazam","C012255","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"12116722","[Psychomotor slowness of a mentally retarded woman].","12116722",42]
["Clomipramine","Clomipramine","D002997","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1977,"600897","The effect of depression and its treatment on serum thyroxine.","600897",42]
["Cycloheximide","Cycloheximide","D003513","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"3917692","Effects of cycloheximide on inverse regulation of phenolic and nonphenolic ring deiodinases in monkey hepatocarcinoma cells.","3917692",42]
["Danazol","Danazol","D003613","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1979,"88918","Danazol and thyroid function.","88918",42]
["desethylamiodarone","desethylamiodarone","C036116","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1990,"2401231","Thyroxine, 3,5,3'-triiodothyronine, and 3,3',5'-triiodothyronine concentrations in several tissues of the rat: effects of amiodarone and desethylamiodarone on thyroid hormone metabolism [corrected].","2401231",42]
["Dexamethasone","Dexamethasone","D003907","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"11478409","Effect of dexamethasone on TSH secretion induced by TRH in human obesity.","11478409",42]
["Dexamethasone","Dexamethasone","D003907","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"7744665","Effect of dexamethasone administration on serum thyroid hormone concentrations in clinically normal horses.","7744665",42]
["Diazepam","Diazepam","D003975","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1975,"809222","On the interaction between thyroid hormones and the tranquillisers Librium and Valium.","809222",42]
["Diethylnitrosamine","Diethylnitrosamine","D004052","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2009,"19899716","[Inhibitory effect of thyroxine on late stages of hepatocarcinogenesis induced in suckling mice by diethylnitrosamine].","19899716",42]
["Digoxin","Digoxin","D004077","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1975,"1137923","Standardization of incubation time and temperature for eight radioimmunoassays.","1137923",42]
["Dopamine","Dopamine","D004298","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2004,"15562452","Endocrine response to fasting in the overwintering captive raccoon dog (Nyctereutes procyonoides).","15562452",42]
["Dopamine","Dopamine","D004298","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"3919973","Evidence for differing dopaminergic activity in childhood- or adult-onset obesity.","3919973",42]
["Drinking Water","Drinking Water","D060766","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"25796570","Iodine supplementation and drinking-water perchlorate mitigation.","25796570",42]
["Epinephrine","Epinephrine","D004837","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14210679","ANALYSIS OF THE ACTIONS OF THE HORMONAL ANTAGONISTS OF INSULIN.","14210679",42]
["Epinephrine","Epinephrine","D004837","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"3766027","Relationships between thyroid hormone and catecholamines in experimental trauma.","3766027",42]
["Epinephrine","Epinephrine","D004837","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1973,"4728067","Biochemical and morphological alterations induced by long-term administration of epinephrine, metanephrine and thyroxine in rats.","4728067",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C104387,B104387)","v":"Epinephrine"},"Epinephrine","D004837","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J104387,K104387)","v":"Thyroxine"},"D013974","Thyroxine",2,2,1981,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q104387,Q104387)","v":"7223318"},"Thyroid hormone-catecholamine interrelationships during exposure to cold.","7223318",42]
["Ethanol","Ethanol","D000431","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1975,"1100436","Liver hypermetabolic state after chronic ethanol consumption: hormonal interrelations and pathogenic implications.","1100436",42]
["Ethylenethiourea","Ethylenethiourea","D005031","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1976,"990524","Metabolic fate of ethylenethiourea in pregnant rats.","990524",42]
["ferric nitrilotriacetate","ferric nitrilotriacetate","C020326","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2004,"15147233","Amelioration by active hexose correlated compound of endocrine disturbances induced by oxidative stress in the rat.","15147233",42]
["Fluphenazine","Fluphenazine","D005476","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2005,"15669892","Thyroid function in treatment-resistant schizophrenia patients treated with quetiapine, risperidone, or fluphenazine.","15669892",42]
["Genistein","Genistein","D019833","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2010,"20463299","Suppressive effects of genistein and daidzein on pituitary-thyroid axis in orchidectomized middle-aged rats.","20463299",42]
["Glucose","Glucose","D005947","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2007,"17585691","Thyroid dysfunction modulates glucoregulatory mechanism in rat.","17585691",42]
["Glucose","Glucose","D005947","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"3337234","Influence of hormones on glycogen and glucose metabolism in embryonic chick intestine.","3337234",42]
["Glucose","Glucose","D005947","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6392059","The influence of glucose and insulin infusion on in vitro T4 Monodeiodination in rat liver microsomes.","6392059",42]
["Gossypol","Gossypol","D006072","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6724725","Serum potassium and aldosterone levels in gossypol-treated rats.","6724725",42]
["Halothane","Halothane","D006221","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"7277674","[Effects of halothane anesthesia and minor surgery on thyroid function in children (author's transl)].","7277674",42]
["Hexachlorobenzene","Hexachlorobenzene","D006581","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"11171930","Association between serum concentrations of hexachlorobenzene and polychlorobiphenyls with thyroid hormone and liver enzymes in a sample of the general population.","11171930",42]
["hydroxyhexamide","hydroxyhexamide","C020362","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"2013345","A case of acetohexamide-induced hypoglycemia: the influence of hypothyroidism on the metabolism of acetohexamide.","2013345",42]
["Industrial Waste","Industrial Waste","D007220","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2007,"17549538","Increased thyroid hormone levels in tree swallows (Tachycineta bicolor) on reclaimed wetlands of the athabasca oil sands.","17549538",42]
["iomeglamic acid","iomeglamic acid","C002060","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"3727645","[Modification of the diagnosis of thyroid gland function by iodine-containing roentgen contrast media].","3727645",42]
["Iopanoic Acid","Iopanoic Acid","D007480","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1979,"517049","Effects of three-day oral cholecystography on serum iodothyronines and TSH concentrations: comparison of the effects among some cholecystographic agents and the effects of iopanoic acid on the pituitary-thyroid axis.","517049",42]
["Isoproterenol","Isoproterenol","D007545","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1996,"8935711","The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries.","8935711",42]
["Lactic Acid","Lactic Acid","D019344","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28102776","Targeted delivery of cisplatin to tumor xenografts via the nanoparticle component of nano-diamino-tetrac.","28102776",42]
["Lithium Carbonate","Lithium Carbonate","D016651","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2000,"10770459","Thyroid function and psychiatric morbidity in patients with manic disorder receiving lithium therapy.","10770459",42]
["Liver Glycogen","Liver Glycogen","D008112","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1969,"4976272","Effect of hypophysectomy of young cockerels, with particular reference to body growth, liver weight, and liver glycogen level.","4976272",42]
["Mercuric Chloride","Mercuric Chloride","D008627","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2004,"15303713","Adverse effects of mercuric chloride on thyroid of mice, Musculus albinus and pattern of recovery of the damaged activity.","15303713",42]
["Metformin","Metformin","D008687","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2013,"23758637","Are levothyroxine requirements lower in thyroidectomized diabetic patients on metformin treatment?","23758637",42]
["Methimazole","Methimazole","D008713","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2003,"12872361","Improved radiation protection of the thyroid gland with thyroxine, methimazole, and potassium iodide during diagnostic and therapeutic use of radiolabeled metaiodobenzylguanidine in children with neuroblastoma.","12872361",42]
["Methimazole","Methimazole","D008713","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28162094","Persistent Graves' hyperthyroidism despite rapid negative conversion of thyroid-stimulating hormone-binding inhibitory immunoglobulin assay results: a case report.","28162094",42]
["Methimazole","Methimazole","D008713","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1983,"6685048","Differential effects of propylthiouracil, methimazole and thyroidectomy on liver ferritin.","6685048",42]
["Methimazole","Methimazole","D008713","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,3,1996,"8656146","Comparison of standardized initial doses of two antithyroid drugs in the treatment of Graves' disease.","8656146",42]
["Methylcellulose","Methylcellulose","D008747","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"4289748","The management of keratoconjuctivitis sicca.","4289748",42]
["Methylprednisolone","Methylprednisolone","D008775","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1972,"4345712","Effect of methylprednisolone in epinephrine-thyroxine induced arteriosclerosis.","4345712",42]
["Methylthiouracil","Methylthiouracil","D008779","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1982,"7082178","[Effect of thyroxine and methylthiouracil on the development of intramural ganglia in the chick embryo digestive tube].","7082178",42]
["Milrinone","Milrinone","D020105","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"2968801","Calcium channel blocker inhibition of the calmodulin-dependent effects of thyroid hormone and milrinone on rabbit myocardial membrane Ca2+-ATPase activity.","2968801",42]
["Morphine","Morphine","D009020","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1978,"660036","Effect of morphine, naloxone and an enkephalin analogue on plasma prolactin, growth hormone, insulin and thyroxine in goats [proceedings].","660036",42]
["Nifedipine","Nifedipine","D009543","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1982,"6819132","Effect of calcium antagonists on thyrotropin and thyroid hormone secretion.","6819132",42]
["Norepinephrine","Norepinephrine","D009638","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14279186","EFFECT OF GUANETHIDINE AND BRETYLIUM ON HEART RATE RESPONSES TO THYROXINE.","14279186",42]
["Norepinephrine","Norepinephrine","D009638","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1979,"419915","Thyroid and adrenomedullary reactions during sleep deprivation.","419915",42]
["Norepinephrine","Norepinephrine","D009638","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"6033666","Response of rat atrium to propranolol and catecholamines in various states of thyroid action.","6033666",42]
["Omeprazole","Omeprazole","D009853","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2575158","Studies on the effects of omeprazole on thyroid function in the rat.","2575158",42]
["oxcarbazepine","oxcarbazepine","C036006","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2004,"15319835","[Hashimoto encephalopathy].","15319835",42]
["Patulin","Patulin","D010365","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2004,"15046817","Investigation of the effects of patulin on thyroid and testis, and hormone levels in growing male rats.","15046817",42]
["Pentobarbital","Pentobarbital","D010424","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"5911539","The influence of thyroid status on the effects and metabolism of pentobarbital and thiopental.","5911539",42]
["Petroleum","Petroleum","D010578","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"6112094","Plasma corticosterone and thyroxine concentrations during chronic ingestion of crude oil in mallard ducks (Anas platyrhynchos).","6112094",42]
["Phenobarbital","Phenobarbital","D010634","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1969,"5764302","Effect of phenobarbital administration on the subcellular distribution of 125-I-thyroxine in rat liver: mportance of microsomal binding.","5764302",42]
["Phenylephrine","Phenylephrine","D010656","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1990,"2347907","Decreased sensitivity to alpha-adrenergic stimulation in hypothyroid patients.","2347907",42]
["Polyethyleneimine","Polyethyleneimine","D011094","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"27847224","Tetraiodothyroacetic acid-conjugated polyethylenimine for integrin receptor mediated delivery of the plasmid encoding IL-12 gene.","27847224",42]
["Potassium Iodide","Potassium Iodide","D011193","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14339393","FAMILIAL IODIDE-INDUCED GOITER. EVIDENCE FOR AN ABNORMALITY IN THE PITUITARY-THYROID HOMEOSTATIC CONTROL.","14339393",42]
["Potassium Iodide","Potassium Iodide","D011193","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"4161993","Further studies on inhibitory effect of excess iodide on thyroidal hormone release in the rat.","4161993",42]
["potassium perchlorate","potassium perchlorate","C009006","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"2854798","[Behavior of the cardiologist when faced with amiodarone-induced hormonal changes].","2854798",42]
["Prednisolone","Prednisolone","D011239","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"2035915","Effect of oral administration of prednisolone on thyroid function in dogs.","2035915",42]
["Prednisone","Prednisone","D011241","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"22167590","Hypothyroidism in children with steroid-resistant nephrotic syndrome.","22167590",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C106947,B106947)","v":"Propranolol"},"Propranolol","D011433","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J106947,K106947)","v":"Thyroxine"},"D013974","Thyroxine",2,2,1976,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q106947,Q106947)","v":"1108824"},"Propranolol as primary therapy for thyrotoxicosis.","1108824",42]
["Propranolol","Propranolol","D011433","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2923254","Failure of chronic beta-adrenergic blockade to inhibit overfeeding-induced thermogenesis in humans.","2923254",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C107075,B107075)","v":"Propranolol"},"Propranolol","D011433","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J107075,K107075)","v":"Thyroxine"},"D013974","Thyroxine",2,2,1993,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q107075,Q107075)","v":"8482496"},"The effects of propranolol on skeletal muscle contraction, lipid peroxidation products and antioxidant activity in experimental hyperthyroidism.","8482496",42]
["Propylthiouracil","Propylthiouracil","D011441","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2000,"10928947","Direct effects of propylthiouracil on testosterone secretion in rat testicular interstitial cells.","10928947",42]
["Propylthiouracil","Propylthiouracil","D011441","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14172717","THYROIDAL INFLUENCE ON EXPERIMENTAL CHOLESTEROL ATHEROSCLEROSIS.","14172717",42]
["Propylthiouracil","Propylthiouracil","D011441","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1975,"174241","Effect of partial thyroidectomy, propylthiouracil or thyroxine on estrogen-induced intranuclear inclusions in mammotrophs of the Mongolian gerbil.","174241",42]
["Propylthiouracil","Propylthiouracil","D011441","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"4169407","An essential role of thyroxine and triiodothyronine balance in establishing normal pituitary-thyroid feedback control in goitrogen-treated rats.","4169407",42]
["Propylthiouracil","Propylthiouracil","D011441","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1969,"5761969","Inhibition of thyrotrophin secretion and deiodination of thyroxine.","5761969",42]
["Propylthiouracil","Propylthiouracil","D011441","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"6894929","Treatment of hyperthyroidism with sodium ipodate (oragrafin) in addition to propylthiouracil and propranolol.","6894929",42]
["Pyridoxal Phosphate","Pyridoxal Phosphate","D011732","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1957,"13430754","Inhibition by thyroxine of enzymes requiring pyridoxal-5-phosphate.","13430754",42]
["Raloxifene Hydrochloride","Raloxifene Hydrochloride","D020849","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2003,"12796075","Raloxifene causing malabsorption of levothyroxine.","12796075",42]
["Reserpine","Reserpine","D012110","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"5898247","Effects of hydrocortisone, thyroxine, reserpine and monoamine oxidase inhibitors on the blood glucose of rats under diethyl ether  anaesthesia.","5898247",42]
["Ritodrine","Ritodrine","D012312","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"2847107","Combined effects of corticosteroid, thyroid hormones, and beta-agonist on surfactant, pulmonary mechanics, and beta-receptor binding in fetal lamb lung.","2847107",42]
["Serotonin","Serotonin","D012701","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1969,"4187716","Amines and mouse thyroid activity: a thyroid-stimulating effect of 5-hydroxytryptamine and dopamine.","4187716",42]
["Sertraline","Sertraline","D020280","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1997,"9312673","Elevated serum thyrotropin in thyroxine-treated patients with hypothyroidism given sertraline.","9312673",42]
["Sodium Chloride","Sodium Chloride","D012965","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"4234298","[The influence of certain solutions on strophosomus induced by thyroxine in the chick embryo].","4234298",42]
["Sodium Iodide","Sodium Iodide","D012974","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1992,"1518372","Effects of inorganic iodide, epidermal growth factor and phorbol ester on hormone synthesis by porcine thyroid follicles cultured in suspension.","1518372",42]
["Spironolactone","Spironolactone","D013148","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1980,"6451886","Failure of the aldosterone antagonist spironolactone to inhibit myocardial hypertrophy produced by experimental hyperthyroidism and accompanied by \"apparent\" digoxin immunoreactivity in the blood.","6451886",42]
["Sulfadimethoxine","Sulfadimethoxine","D013412","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1997,"9125776","Comparison of ultrastructural changes in thyrotrophs of the rat pituitary between intermittent and continuous treatments with sulfadimethoxine.","9125776",42]
["talinolol","talinolol","C011550","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"22339773","Effects of rifampicin, dexamethasone, St. John's Wort and Thyroxine on maternal and foetal expression of Abcb1 and organ distribution of talinolol in pregnant rats.","22339773",42]
["Thiamine","Thiamine","D013831","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1955,"14361732","Effect of riboflavin or thiamin deficiency on the response of liver and kidney adenosinetriphosphatase and D-amino acid oxidase to thyroid and adrenal alterations in rats.","14361732",42]
["Thiouracil","Thiouracil","D013889","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1953,"13026022","THYROXINE and thiouracil on milk composition.","13026022",42]
["Thiouracil","Thiouracil","D013889","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14131769","THE EFFECTS OF VARIOUS GOITROGENS ON THE DETERMINATION OF THE RELATIVE POTENCY OF THYROID BY THE GOITRE PREVENTION ASSAY.","14131769",42]
["Thiouracil","Thiouracil","D013889","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2925084","Corticosteroid receptors in liver cytosol of the clawed toad, Xenopus laevis: influence of thyroid and ovarian hormones.","2925084",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1952,"12979293","[Auto-historadiography in iodine metabolism in thyroid formation in the Lebistes reticulatus treated with thyroxin, iodized proteins or thiourea].","12979293",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1952,"12988471","[The effects produced by prolonged administration of thiourea and thyroxin in Lebistes reticulatus].","12988471",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1953,"13099381","Effect of thiourea and thyroxine on oxygen uptake of tissue homogenates.","13099381",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"13969550","On the responses of the glandular tracts and associated regions of the endostyle of the larval lamprey to goitrogens and thyroxine.","13969550",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14066294","FURTHER STUDIES ON THE THYROIDAL CONTROL OF RADIOPHOSPHORUS METABOLISM AS DETERMINED BY THE EFFECTS OF THYROXINE AND PITUITARY EXTRACT ON THIOUREA AND RADIOIODINE TREATED GOLDFISH, CARASSIUS AURATUS L.","14066294",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14076705","THYROID GLAND AND TEMPERATURE TOLERANCE RELATIONSHIPS IN COLD-BLOODED VERTEBRATES.","14076705",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14081714","[INFLUENCE OF THE THYROID GLAND ON THE ENDOCRINE PANCREAS OF RANA ESCULENTA (L.)].","14081714",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14105463","THYROID FUNCTION IN GUINEA PIGS AFTER REPEATED TREATMENT WITH THIOUREA.","14105463",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14116576","REGULATION OF THYROID FUNCTION IN THE TOAD BUFO BUFO.","14116576",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14117472","EFFECT OF THYROXINE ON THYROID UPTAKE OF THIOUREA-S35.","14117472",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14170790","DISSOCIATION OF IODINATION FROM PROTEIN SYNTHESIS IN THE RAT THYROID.","14170790",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14187327","AN AUTORADIOGRAPHIC STUDY OF THE HYPOPHYSIS OF CARASSIUS AURATUS BY ADMINISTRATION OF NA2-S35-O-4 AFTER TREATMENT WITH THIOUREA OR THYROXINE.","14187327",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1955,"14370205","Modulating action of the thyroid on oestrogen-induced pituitary tumours in rats.","14370205",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1962,"14491316","[Interrelations between a strumigen (allylthiourea), iodine and thyroxin. II. The empirical dependence of thyroid gland weight on the daily dosage of allylthiourea, iodide and thyroxin in rats].","14491316",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1949,"15402205","Metabolic effects of thyroxine injected into normal, thiouracil-treated and thyroidectomized rats.","15402205",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1949,"15407504","The effects of thyroxin and thiouracil on the time of appearance of ossification centers of rat fetuses.","15407504",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1950,"15434990","[Mechanism of action of antithyroid drugs: inhibition of the peripheral effect of thyroxin].","15434990",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1949,"18152132","The effect of thyroxin in thyroidectomized rats treated with methylthiouracyl.","18152132",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1977,"197869","Prolactin content of the pituitary gland in response to hypertonic saline medium, antithyroid drugs, methallibure and thyroxine in a freshwater teleost Heteropneustes fossilis.","197869",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1946,"20982070","Tolerance of normal, of thyroidectomized, and of thiourea or thiouracil treated dogs to oral desiccated thyroid and to intravenous thyroxine.","20982070",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1946,"21017604","Granulocytopenia in rats given thiourea and thyroxin; the therapeutic effect of L. casei factor.","21017604",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2496675","Effect of thyroxine (T4) and thiourea on the hepatic oxygen consumption of male garden lizards of three different age groups.","2496675",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3122291","Lung development under the influence of thiourea and L-thyroxine. Retarding and toxic effects of thiourea.","3122291",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"3141248","Age-related changes in the response of hepatic succinic dehydrogenase activity to thyroxine and thiourea in lizards.","3141248",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"4184748","The anterior pituitary of the Japanese quail, Coturnix coturnix japonica. The cytological effects of photoperiodic stimulation.","4184748",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1979,"437690","Effect of thiourea on intracranial bone tumour formation in AkR mice.","437690",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C108227,B108227)","v":"Thiourea"},"Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J108227,K108227)","v":"Thyroxine"},"D013974","Thyroxine",2,4,1974,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q108227,Q108227)","v":"4434978"},"[Modification of the function in rat's thyroid by Turisynchron and Suisynchron].","4434978",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1971,"5004766","Effect of thyroxine and thiourea on the alkaline and acid phosphatase activity in liver of tadpoles at various stages of development of larval life.","5004766",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1969,"5381117","Effect of thyroxine and thiourea on glycogen neutral lipid and protein contents in liver of tadpoles.","5381117",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1970,"5487159","Thyroid hormone effects on chick scale morphogenesis and keratinization.","5487159",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"5665312","Respiratory and behavioral responses of Poecilia to treatment with thyroxine and thiourea.","5665312",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1979,"571829","Hypothalamo-adenohypophyseal-thyroid interrelationships in the chick embryo. II. Effects of thiourea treatment on plasma total thyroxine levels and thyroidal 125I uptake.","571829",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"5728201","Endocrine influences on growth and pigmentation of embryonic down feather cells.","5728201",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"5963172","Mitotic activity in the lumbosacral spinal cord of Rana pipiens larvae after thyroxine or thiourea treatment.","5963172",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"5980555","Influence of thyroid state upon optically evoked potentials in the midbrain of goldfish.","5980555",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"6033864","Responses of pituitary cells of Poecilia to changes in growth induced by thyroxine and thiourea.","6033864",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1983,"6136371","Motility pattern and lung respiration of embryonic chicks under the influence of L-thyroxine and thiourea.","6136371",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1982,"6175427","Effect of thyroid hormones on the switch from larval to adult hemoglobin synthesis in the salamander Pleurodeles waltlii.","6175427",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1983,"6408217","Effect of hypophysectomy by partial decapitation and treatment with thiourea on iodine metabolism in the developing chick embryo.","6408217",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1983,"6414723","Activation of xanthine dehydrogenase during the prenatal period through L-thyroxine, thiourea and cycloheximide.","6414723",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6425113","Changes in morphometric parameters and the characteristics of collagen following thyroxine and thiourea treatments in young male garden lizards.","6425113",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6425114","Thyroid hormones and carbohydrate metabolism of brain in the teleost, Channa punctatus. I. Effect of T4 and thiourea on succinic dehydrogenase (SDH) activity and protein content.","6425114",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1978,"676096","Thiourea does not block visual pigment responses to prolactin in trout.","676096",42]
["Thiourea","Thiourea","D013890","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1996,"8616805","Promoting effect of large amounts of vitamin A on cell proliferation of thyroid proliferative lesions induced by simultaneous treatment with thiourea.","8616805",42]
["Thromboxane A2","Thromboxane A2","D013928","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3668359","Effects of hypothyroidism and short-term aging on whole blood thromboxane and arterial prostacyclin synthesis.","3668359",42]
["Thymol","Thymol","D013943","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14087598","ELEVATION OF THE SERUM PROTEIN-BOUND IODINE IN ACUTE INTERMITTENT PORPHYRIA.","14087598",42]
["thymostimulin","thymostimulin","C031407","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2002,"12575542","[Changes in immunogenesis organs after thyroidectomy and hormonal correction in an experiment].","12575542",42]
["thymostimulin","thymostimulin","C031407","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2003,"14965037","[Effect of thymostimulin on endocrine thymus function in thyroidectomized rats during suppressive hormone therapy].","14965037",42]
["tibolone","tibolone","C027385","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2007,"18210897","Effect of different hormonal therapies on thyroid function in surgical menopause: short-term results.","18210897",42]
["TK 12627","TK 12627","C066840","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8317193","Effect of the antioxidant TK 12627 (Irganox) on monodeiodination and on the levels of messenger ribonucleic acid of 5'-deiodinase type I and spot 14.","8317193",42]
["Tobacco Smoke Pollution","Tobacco Smoke Pollution","D014028","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2007,"17077134","A brief exposure to moderate passive smoke increases metabolism and thyroid hormone secretion.","17077134",42]
["Tobacco Smoke Pollution","Tobacco Smoke Pollution","D014028","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"1877292","Effect of smoking on different biological parameters in aging mice.","1877292",42]
["Tobacco Smoke Pollution","Tobacco Smoke Pollution","D014028","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2009,"19505184","Thyroid hormone levels associated with active and passive cigarette smoking.","19505184",42]
["tobanum","tobanum","C025725","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1979,"45285","Effect of beta-blocking agents in hyperthyroidism.","45285",42]
["Tolazamide","Tolazamide","D014042","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"2943619","Differential activities of tolbutamide, tolazamide, and glyburide in vitro on rabbit myocardial membrane Ca2+-transporting ATPase activity.","2943619",42]
["Tolazoline","Tolazoline","D014043","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1977,"411747","Thyroxine and tolazoline hydrochloride in the prevention of cold injury.","411747",42]
["Tolbutamide","Tolbutamide","D014044","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1962,"13977373","Effects of sulfonylurea compounds on hyperlipemia and hypercholesteremia in patients with minimal impairment of glucose tolerance.","13977373",42]
["Tolbutamide","Tolbutamide","D014044","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"2943619","Differential activities of tolbutamide, tolazamide, and glyburide in vitro on rabbit myocardial membrane Ca2+-transporting ATPase activity.","2943619",42]
["Tolbutamide","Tolbutamide","D014044","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"4972270","Effect of sulfonylurea drugs on the binding of triiodothyronine and thyroxine to thyroxine-binding globulin.","4972270",42]
["Tolbutamide","Tolbutamide","D014044","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1969,"5401637","[Influence of tolbutamide on the binding capacity of serum protenns for I-131 thyroxine, I-131 insulin and cortisol].","5401637",42]
["Tolbutamide","Tolbutamide","D014044","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"5659433","Effects of sulfonylurea drugs on the thyroid and serum protein binding of thyroxine in the rat.","5659433",42]
["Tolbutamide","Tolbutamide","D014044","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6397025","Effect of iodine administration on thyroid function in diabetic patients.","6397025",42]
["topiramate","topiramate","C052342","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"11719917","Developments in mood stabilisers.","11719917",42]
["Toremifene","Toremifene","D017312","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1990,"2142236","Effect of toremifene on clinical chemistry, hematology and hormone levels at different doses in healthy postmenopausal volunteers: phase I study.","2142236",42]
["Tranylcypromine","Tranylcypromine","D014191","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2000,"10665823","Effects of tranylcypromine on thyroid hormone metabolism and concentrations in rat brain.","10665823",42]
["Tranylcypromine","Tranylcypromine","D014191","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14252047","THE RELATIONSHIP BETWEEN MYOCARDIAL CATECHOLAMINES AND THE HEART RATE.","14252047",42]
["Tranylcypromine","Tranylcypromine","D014191","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1998,"9585722","Integrating pharmacotherapy and psychotherapy in the treatment of a bipolar patient.","9585722",42]
["Tremorine","Tremorine","D014203","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"4385048","The effects of tremorine and oxotremorine in hyperthyroid mice.","4385048",42]
["Trenbolone Acetate","Trenbolone Acetate","D014204","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2006,"16543582","Effects of growth-promoting agents and season on blood metabolites and body temperature in heifers.","16543582",42]
["Trenbolone Acetate","Trenbolone Acetate","D014204","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"7017853","Growth hormone, insulin, prolactin and total thyroxine in the plasma of sheep implanted with the anabolic steroid trenbolone acetate alone or with oestradiol.","7017853",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2002,"12462521","The regulation of the thyroid-stimulating hormone of the anterior pituitary gland by thyroid hormone and by 9-cis-retinoic acid.","12462521",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1992,"1464411","Comparative effects of thyroxine and/or retinoic acid treatment in vivo on growth hormone synthesis and release by pituitaries from thyroidectomized rats.","1464411",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1992,"1493378","Effects of epidermal growth factor, phorbol ester, and retinoic acid on hormone synthesis and morphology in porcine thyroid follicles cultured in collagen gel.","1493378",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2004,"15316095","Beneficial effect of retinoic acid on the outcome of experimental acute renal failure.","15316095",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,4,1992,"1534654","Stereochemical requirements for the modulation by retinoic acid of thyroid hormone activation of Ca(2+)-ATPase and binding at the human erythrocyte membrane.","1534654",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"1825017","Sex-dependent inhibition by retinoic acid of thyroid-hormone action on rabbit reticulocyte Ca2(+)-ATPase activity.","1825017",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"1988285","Retinoids enhance lectin binding to gp130, a glycoprotein of NIH-3T3 cells: correlation with cell growth and adhesion.","1988285",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2010,"20212023","Retinoic acid modulation of thyroid dual oxidase activity in rats and its impact on thyroid iodine organification.","20212023",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2010,"20573951","Retinoic acid induces expression of the thyroid hormone transporter, monocarboxylate transporter 8 (Mct8).","20573951",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2011,"21886774","Phenothiourea sensitizes zebrafish cranial neural crest and extraocular muscle development to changes in retinoic acid and IGF signaling.","21886774",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"21924320","Multifaceted suppression of aggressive behavior of thyroid carcinoma by all-trans retinoic acid induced re-differentiation.","21924320",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2521337","Retinoic acid is a modulator of thyroid hormone activation of Ca2+-ATPase in the human erythrocyte membrane.","2521337",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"2938851","Lack of effect of isotretinoin on thyroid-function tests.","2938851",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3452601","Enzymic oxidation of vitamin A aldehyde to vitamin A acid by rat livers of experimental thyroid disorders.","3452601",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1983,"6651227","Thyroid hormones in vitamin A-deficient rats: effect of retinoic acid supplementation.","6651227",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"7720661","Cell-type specific interactions between retinoic acid and thyroid hormone in the regulation of expression of the gene encoding ornithine aminotransferase.","7720661",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1994,"8280758","Retinoic acid inhibition of thyroxine binding to human transthyretin.","8280758",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8423438","Retinoic acid, cortisone, or thyroxine suppresses the mutant phenotype of the eyelid development mutation, lgMl, in mice.","8423438",42]
["Tretinoin","Tretinoin","D014212","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"8536704","Crystal structure of the transthyretin--retinoic-acid complex.","8536704",42]
["triadimefon","triadimefon","C032910","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2016,"27480594","Impact of co-exposure with butachlor and triadimefon on thyroid endocrine system in larval zebrafish.","27480594",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C108291,B108291)","v":"Triamcinolone"},"Triamcinolone","D014221","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J108291,K108291)","v":"Thyroxine"},"D013974","Thyroxine",2,2,1976,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q108291,Q108291)","v":"177277"},"Hormonal control of renal phosphoenolpyruvate carboxykinase activity during development of the rat.","177277",42]
["Triamcinolone","Triamcinolone","D014221","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"26019115","Long-term follow-up and epidemiological trends in patients with pretibial myxedema: an 11-year study from a tertiary care center in northern India.","26019115",42]
["Triamcinolone","Triamcinolone","D014221","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1970,"4398481","Prevention of colchicine intoxication by catatoxic steroids.","4398481",42]
["Triamcinolone","Triamcinolone","D014221","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1973,"4786524","Studies on cystathionase activity in rat liver and brain during development. Effects of hormones and amino acids in vivo.","4786524",42]
["Triamcinolone","Triamcinolone","D014221","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1971,"4996433","Hormonal influences upon ethylene glycol poisoning.","4996433",42]
["Triamcinolone","Triamcinolone","D014221","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1972,"5030044","Effect of various steroids and nonsteroidal microsomal enzyme inducers upon propoxyphene intoxication.","5030044",42]
["Triamcinolone","Triamcinolone","D014221","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1980,"6155138","Hormonal regulation of liver pyruvate kinase concentration and activity.","6155138",42]
["tributyltin","tributyltin","C011559","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2003,"12773765","Effects of in utero tributyltin chloride exposure in the rat on pregnancy outcome.","12773765",42]
["Trichloroacetic Acid","Trichloroacetic Acid","D014238","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14334735","PROTEIN-BOUND IODINE DETERMINATION WITH STABLE END POINT.","14334735",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2009,"18940961","The effects of triclosan on puberty and thyroid hormones in male Wistar rats.","18940961",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2009,"19686543","Human exposure to triclosan via toothpaste does not change CYP3A4 activity or plasma concentrations of thyroid hormones.","19686543",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2010,"19910387","Short-term exposure to triclosan decreases thyroxine in vivo via upregulation of hepatic catabolism in Young Long-Evans rats.","19910387",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2010,"20954233","Developmental triclosan exposure decreases maternal and neonatal thyroxine in rats.","20954233",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2011,"21436124","Triclosan and thyroid-mediated metamorphosis in anurans: differentiating growth effects from thyroid-driven metamorphosis in Xenopus laevis.","21436124",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"22197412","Long term use of triclosan toothpaste and thyroid function.","22197412",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,4,2012,"22659317","Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: a dynamic and kinetic evaluation of a putative mode-of-action.","22659317",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2013,"23340023","Relationship between urinary triclosan and paraben concentrations and serum thyroid measures in NHANES 2007-2008.","23340023",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2013,"23831729","Triclosan exposure reduces thyroxine levels in pregnant and lactating rat dams and in directly exposed offspring.","23831729",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"25499511","Triclosan and triclosan-loaded liposomal nanoparticles in the treatment of acute experimental toxoplasmosis.","25499511",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2016,"27156197","Application of the Navigation Guide systematic review methodology to the evidence for developmental and reproductive toxicity of triclosan.","27156197",42]
["Triclosan","Triclosan","D014260","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28973666","Exposure of Pregnant Mice to Triclosan Causes Insulin Resistance via Thyroxine Reduction.","28973666",42]
["triethyl phosphate","triethyl phosphate","C009549","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"24998971","Tris(2-butoxyethyl)phosphate and triethyl phosphate alter embryonic development, hepatic mRNA expression, thyroid hormone levels, and circulating bile acid concentrations in chicken embryos.","24998971",42]
["Triethylenemelamine","Triethylenemelamine","D014265","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1959,"13827492","[Phosphate metabolism in pigeon and human erythrocytes under the influence of 2,4-dinitrophenol, sodium cyanide, monoidoacetate and of thyroxin and triethylens melamine. Comparative studies using P32-marked orthophosphate].","13827492",42]
["Trifluoperazine","Trifluoperazine","D014268","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"1887879","Effects of calmodulin antagonists on hydrogen-translocating shuttles in perfused rat liver.","1887879",42]
["Trifluralin","Trifluralin","D014274","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2008,"18582544","Mechanism of trifluralin-induced thyroid tumors in rats.","18582544",42]
["Trimethaphan","Trimethaphan","D014294","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1959,"13812690","[Effect of a ganglion-blocking drug of rapid action on thyroid content of thyroxin-bound iodine].","13812690",42]
["Trimethoprim","Trimethoprim","D014295","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1992,"1477803","Effect of oral administration of sulfadiazine and trimethoprim in combination on thyroid function in dogs.","1477803",42]
["Trimethoprim","Trimethoprim","D014295","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"6110911","Trimethoprim and thyroid function.","6110911",42]
["Trimethoprim","Trimethoprim","D014295","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"6975345","Effects of trimethoprim and sulphonamide preparations on the pituitary-thyroid axis of rodents.","6975345",42]
["Trimethoprim","Trimethoprim","D014295","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8229966","Lack of effect of trimethoprim and sulfadiazine in combination in mid- to late gestation on thyroid function in neonatal dogs.","8229966",42]
["Trimethoprim, Sulfamethoxazole Drug Combination","Trimethoprim, Sulfamethoxazole Drug Combination","D015662","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,3,2002,"12322917","Effects of short-term trimethoprim-sulfamethoxazole administration on thyroid function in dogs.","12322917",42]
["Trimethoprim, Sulfamethoxazole Drug Combination","Trimethoprim, Sulfamethoxazole Drug Combination","D015662","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2005,"15757124","Effects of sulfamethoxazole-trimethoprim on thyroid function in dogs.","15757124",42]
["Trimethoprim, Sulfamethoxazole Drug Combination","Trimethoprim, Sulfamethoxazole Drug Combination","D015662","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2006,"17069024","Dose-dependant hypothyroidism in mice induced by commercial trimethoprim-sulfamethoxazole rodent feed.","17069024",42]
["Trimethoprim, Sulfamethoxazole Drug Combination","Trimethoprim, Sulfamethoxazole Drug Combination","D015662","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2008,"18412530","Goitrous hypothyroidism associated with treatment with trimethoprim-sulfamethoxazole in a young dog.","18412530",42]
["Trimethoprim, Sulfamethoxazole Drug Combination","Trimethoprim, Sulfamethoxazole Drug Combination","D015662","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"6975345","Effects of trimethoprim and sulphonamide preparations on the pituitary-thyroid axis of rodents.","6975345",42]
["Trimethoprim, Sulfamethoxazole Drug Combination","Trimethoprim, Sulfamethoxazole Drug Combination","D015662","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8360087","Effect of trimethoprim/sulfamethoxazole on thyroid function in dogs with pyoderma.","8360087",42]
["trimethylamine","trimethylamine","C023336","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"6169485","The inhibition of trimethylamine oxidation in the domestic fowl (Gallus domesticus) ay antithyroid compounds.","6169485",42]
["trimethylamine","trimethylamine","C023336","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"7317811","Thyroid function in relation to trimethylamine oxidation in immature domestic fowl fed on rapeseed meal.","7317811",42]
["tripalmitin","tripalmitin","C005859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"13972877","Effect of dextrothyroxine on metabolism of C-14-labeled cholesterol and tripalmitin.","13972877",42]
["Triparanol","Triparanol","D014308","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14087059","[DRUGS LOWERING THE CHOLESTEROL LEVEL IN THE BLOOD].","14087059",42]
["Triparanol","Triparanol","D014308","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14170885","CORONARY ARTERY DISEASE WITH SPECIAL REFERENCE TO THE EFFECTS OF CHOLESTEROL-LOWERING AGENTS.","14170885",42]
["triphenyl phosphate","triphenyl phosphate","C005445","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28162782","Associations between urinary diphenyl phosphate and thyroid function.","28162782",42]
["triphenyltin hydroxide","triphenyltin hydroxide","C007567","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2006,"16162336","Effects of fentin hydroxide on reproduction of the Japanese quail (Coturnix coturnix japonica).","16162336",42]
["tris(1,3-dichloro-2-propyl)phosphate","tris(1,3-dichloro-2-propyl)phosphate","C016805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"24407104","Tris(1,3-dichloro-2-propyl) phosphate perturbs the expression of genes involved in immune response and lipid and steroid metabolism in chicken embryos.","24407104",42]
["tris(1,3-dichloro-2-propyl)phosphate","tris(1,3-dichloro-2-propyl)phosphate","C016805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"26300399","Neurotoxicological and thyroid evaluations of rats developmentally exposed to tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) and tris(2-chloro-2-ethyl)phosphate (TCEP).","26300399",42]
["tris(1,3-dichloro-2-propyl)phosphate","tris(1,3-dichloro-2-propyl)phosphate","C016805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"26356387","Bioconcentration, metabolism and alterations of thyroid hormones of Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) in Zebrafish.","26356387",42]
["tris(2,2'-bipyridine)ruthenium III","tris(2,2'-bipyridine)ruthenium III","C058901","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2006,"16896249","Flow-injection determination of thyroxine using immobilized enzyme with tris(2,2'-bipyridyl)ruthenium(III) chemiluminescence detection.","16896249",42]
["tris(2-butoxyethyl) phosphate","tris(2-butoxyethyl) phosphate","C013320","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"24998971","Tris(2-butoxyethyl)phosphate and triethyl phosphate alter embryonic development, hepatic mRNA expression, thyroid hormone levels, and circulating bile acid concentrations in chicken embryos.","24998971",42]
["tris(2-butoxyethyl) phosphate","tris(2-butoxyethyl) phosphate","C013320","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28772162","Acute exposure to tris (2-butoxyethyl) phosphate (TBOEP) affects growth and development of embryo-larval zebrafish.","28772162",42]
["tris(2-carboxyethyl)phosphine","tris(2-carboxyethyl)phosphine","C080938","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"26300399","Neurotoxicological and thyroid evaluations of rats developmentally exposed to tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) and tris(2-chloro-2-ethyl)phosphate (TCEP).","26300399",42]
["tropatepine","tropatepine","C013322","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2008,"18031319","Total, free and bound leptin and thyroid function in elderly women with different body weights.","18031319",42]
["Trypan Blue","Trypan Blue","D014343","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14260999","OBSERVATIONS OF THE EFFECT OF ORGANIC DYES AND DIPHENYLHYDANTOIN ON THE IN VITRO BINDING OF RADIOACTIVE 131-I LABELED L-THYROXINE, L-TRIIODOTHYRONINE AND TETRAIODOTHYROACETIC ACID BY HUMAN ERYTHROCYTES AND SERUM PROTEINS.","14260999",42]
["Trypan Blue","Trypan Blue","D014343","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14261413","FURTHER STUDIES ON THE MECHANISM OF ACTION OF TRYPAN BLUE AND RELATED DYES IN SUPPRESSING THYROID ACTIVITY IN THE RAT.","14261413",42]
["Trypan Blue","Trypan Blue","D014343","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1973,"4202137","[Intravital uptake of trypan blue in the epithelial cells of the proximal renal tubule following sublimate intoxication and subsequent treatment with L-thyroxine (author's transl)].","4202137",42]
["Trypan Blue","Trypan Blue","D014343","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"5974902","Comparison of the effects of several drugs on tissue uptake of labeled thyroxine and triiodothyronine in the presence of rat plasma in vitro.","5974902",42]
["Trypan Blue","Trypan Blue","D014343","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"6005925","Influence of thyroid function on the teratogenic activity of trypan blue in the rat.","6005925",42]
["Trypan Blue","Trypan Blue","D014343","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"6266674","Ultrastructural and cytochemical effects of trypan blue on TSH stimulation of thyroid follicular cells.","6266674",42]
["Tuberculin","Tuberculin","D014373","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1954,"13208939","The influence of the thyroid gland on sensitivity to tuberculin in guinea-pigs.","13208939",42]
["Tuberculin","Tuberculin","D014373","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1962,"13914915","Effect of thyroxine treatment on lysis of leukocytes from tuberculin-sensitive guinea pigs.","13914915",42]
["Tuberculin","Tuberculin","D014373","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1952,"14946304","The effects of thyroxine and thiouracil on the tuberculin reactions of guinea-pigs.","14946304",42]
["Tubocurarine","Tubocurarine","D014403","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1962,"13862589","[Action of thyroxin on the block of the neuromuscular synapse with tubocurarine].","13862589",42]
["Tubocurarine","Tubocurarine","D014403","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14116185","[ACTION OF SEVERAL MEDICAMENTS ON RESISTANCE TO COLD STRESS].","14116185",42]
["Tubocurarine","Tubocurarine","D014403","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14265656","THE INFLUENCE OF VARIOUS SUBSTANCES ON METABOLISM AND RESISTANCE OF TRAUMATIZED RATS.","14265656",42]
["Tubocurarine","Tubocurarine","D014403","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1970,"5529556","[Effects of environmental temperature, tubocurarine and pentobarbital on oxygen consumption in thyroidectomized and thyroxine treated rats].","5529556",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C108355,B108355)","v":"turmeric extract"},"turmeric extract","C012596","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J108355,K108355)","v":"Thyroxine"},"D013974","Thyroxine",2,2,2002,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q108355,Q108355)","v":"12587721"},"Effect of antioxidants (vitamin C, E and turmeric extract) on methimazole induced hypothyroidism in rats.","12587721",42]
["Turpentine","Turpentine","D014425","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"2046869","Evidence suggesting that the sympathetic nervous system mediates thyroidal depression in turpentine-induced nonthyroidal illness syndrome.","2046869",42]
["Turpentine","Turpentine","D014425","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"3381625","Alterations in thyroidal economy in a systemic illness induced by turpentine oil injection to the rat.","3381625",42]
["Turpentine","Turpentine","D014425","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3440823","Evidence against benefit from replacement doses of thyroid hormones in nonthyroidal illness (NTI): studies using turpentine oil-injected rat.","3440823",42]
["tyloxapol","tyloxapol","C016811","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14066218","THE BINDING OF THYROIDAL HORMONES BYTRITON WR-1339.","14066218",42]
["Tyramine","Tyramine","D014439","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"13947539","Effect of tyrosine and some of its metabolites on the biosynthesis of ascorbic acid by rat-liver tissues.","13947539",42]
["Tyramine","Tyramine","D014439","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14083968","[ENHANCEMENT OF THE ABSOLUTE TOXICITY OF CERTAIN SYMPATHOMIMETIC AMINES BY THYROXIN].","14083968",42]
["Tyramine","Tyramine","D014439","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14248388","[SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME THYROXINE AND ADRENERGIC DERIVATIVES. IV. SYNTHESIS AND BLOOD PRESSURE AND CARDIAC ACTIVITIES OF 3,5-DIIODODERIVATIVES OF HYPERTENSIVE 4-HYDROXYPHENYLALKYLAMINES].","14248388",42]
["Tyramine","Tyramine","D014439","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2640228","Effect of thyroidectomy on cardiovascular responses to hypoxia and tyramine infusion in fetal sheep.","2640228",42]
["Tyramine","Tyramine","D014439","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1972,"4340224","Metabolic actions of tyramine and McNeil-A-343 in euthyroid and hyperthyroid rats.","4340224",42]
["Tyramine","Tyramine","D014439","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"5981989","[Synthesis and biological activity of certain thyroxine and adrenergic derivatives. VII. Influence of various iodine phenolic derivatives on guinea pig hepatic monoamine oxidase and on rat cerebral monoamine oxidase].","5981989",42]
["ubichromenol","ubichromenol","C003740","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1960,"13819452","Effect of thyroxine and 2,4-dinitrophenol on levels of ubiquinone and ubichromenol in the rat.","13819452",42]
["ubichromenol","ubichromenol","C003740","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14089456","BIOSYNTHESIS OF UBIQUINONE AND UBICHROMENOL.","14089456",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1960,"13819452","Effect of thyroxine and 2,4-dinitrophenol on levels of ubiquinone and ubichromenol in the rat.","13819452",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"13942332","Ubiquinone (coenzyme Q) and the regulation of basal metabolic rate by thryoid hormones.","13942332",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14089456","BIOSYNTHESIS OF UBIQUINONE AND UBICHROMENOL.","14089456",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14104114","[ENZYMATIC DEIODINATION OF THYROXIN AND ITS DERIVATIVES. IV. ROLE OF ELECTRON TRANSPORT SYSTEMS IN THE DEIODINATION OF L-THYROXIN BY RAT LIVER HOMOGENATES IN DARKNESS].","14104114",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14220667","QUANTITATIVE STUDY OF THE EFFECTS OF THYROXINE ON COMPONENTS OF THE ELECTRON-TRANSFER SYSTEM.","14220667",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2005,"16873946","Coenzyme Q10 evaluation in pituitary-adrenal axis disease: preliminary data.","16873946",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2592737","Evaluation of metabolic status in amiodarone-induced thyroid disorders: plasma coenzyme Q10 determination.","2592737",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"2874802","Thyroxine-induced changes in rat liver mitochondrial ubiquinone.","2874802",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3693260","Protective effect of coenzyme Q10 on thyrotoxic heart in rabbits.","3693260",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1969,"5774472","Metabolism of ubiquinone in relation to thyroxine status.","5774472",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6510889","Serum and tissue coenzyme Q9 in rats with thyroid dysfunctions.","6510889",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"7798018","Effects of thyroid hormone on coenzyme Q and other free radical scavengers in rat heart muscle.","7798018",42]
["Ubiquinone","Ubiquinone","D014451","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1996,"8620569","Increases in tissue levels of ubiquinone in association with peroxisome proliferation.","8620569",42]
["ubiquinone 9","ubiquinone 9","C030571","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6510889","Serum and tissue coenzyme Q9 in rats with thyroid dysfunctions.","6510889",42]
["ubiquinone 9","ubiquinone 9","C030571","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"7798018","Effects of thyroid hormone on coenzyme Q and other free radical scavengers in rat heart muscle.","7798018",42]
["UK 453,061","UK 453,061","C531151","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"24135463","Effects of lersivirine on canine and rodent thyroid function.","24135463",42]
["ukrain","ukrain","C060921","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2000,"11345043","Influence of Ukrain on the nuclear thyroid hormone receptors after short-term gamma-irradiation.","11345043",42]
["Uracil","Uracil","D014498","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14209954","URACIL METABOLISM IN TADPOLES DURING THYROXINE-INDUCED METAMORPHOSIS.","14209954",42]
["Uracil","Uracil","D014498","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2003,"15248482","Effects of hypothyroidism induced by 6-n-propylthiouracil and its reversal by T3 on rat heart superoxide dismutase, catalase and lipid peroxidation.","15248482",42]
["Uracil","Uracil","D014498","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2013,"24075770","Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-β agonist.","24075770",42]
["Uracil","Uracil","D014498","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"4158554","Failure to confirm goitrogenic and hypercholesterolemic effects of uracil.","4158554",42]
["Uracil","Uracil","D014498","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"4176909","Effect of changes in trophic hormone secretion on the 3H-uracil uptake by adenohypophyseal cells.","4176909",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1958,"13607278","[Comparative studies on the convulsive effects of insulin and N1-(4-methylbenzene-sulfonyl)-N2-butylurea in mice under normal metabolic conditions and conditions altered by thyroxin treatment].","13607278",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1961,"13728050","Effect of thyroxine on enzymes of the urea cycle in regenerating rat liver.","13728050",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2007,"17700641","Polyuria of thyrotoxicosis: downregulation of aquaporin water channels and increased solute excretion.","17700641",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1977,"188719","The hormonal regulation of urea excretion in the Mexican axoloti (Ambystoma mexicanum Cope).","188719",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1990,"2155152","Intermediary metabolism in a lizard, Calotes versicolor: role of thyroid hormones.","2155152",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"22101979","Responses to graded replacement of urea by maize steep liquor in diets for intensively fed lambs for meat production.","22101979",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28085502","Urea, Uric Acid, Prolactin and fT4 Concentrations in Aqueous Humor of Keratoconus Patients.","28085502",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"2844505","Effect of thyroid hormones on urea biosynthesis and related processes in rat liver.","2844505",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3500675","Thyroxine elicits divergent changes in mRNA levels for two urea cycle enzymes and one gluconeogenic enzyme in tadpole liver.","3500675",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3571019","Effect of protein and energy intake by primiparous sows during lactation on sow and litter performance and sow serum thyroxine and urea concentrations.","3571019",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1972,"4537423","A concerted response of the enzymes of urea biosynthesis during thyroxine-induced metamorphosis of Rana catesbeiana.","4537423",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,4,1971,"4101728","Effect of antigammaglobulin-thyroxine complex on the urea excretion of tadpoles.","4101728",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1970,"4193238","Effect of prolactin, growth hormone and ACTH on the urea excretion of bullfrog tadpoles during normal and induced metamorphosis.","4193238",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1974,"4545799","Thyromimetic activity of methylthyronines in the bullfrog tadpole.","4545799",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1972,"4645767","Possible rate-limiting factors in urea synthesis by the perfused rat liver.","4645767",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1971,"5317078","[Study of the radiosensitivity of the thyroxine-induced synthesis of urea-forming enzymes in tadpoles of Rana temporia].","5317078",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"5642025","Urea excretion in the bullrog tadpole: effect of temperature, metamorphosis, and thyroid hormones.","5642025",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1982,"7097485","Absorption, distribution and elimination of creatinine and urea in hyperthyroid mice.","7097485",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"7250092","Dietary and hormonal regulation of urea cycle enzymes in rat liver.","7250092",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8412738","Hepatic conversion of amino nitrogen to urea nitrogen in hypothyroid patients and upon L-thyroxine therapy.","8412738",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"8594847","[The effect of carbamide feeding over a long period of time on thyroid gland activity in bulls].","8594847",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1997,"9041382","Moderate hyperthyroidism reduces liver amino nitrogen conversion, muscle nitrogen contents and overall nitrogen balance in rats.","9041382",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1997,"9059964","Hepatic amino nitrogen conversion and organ N-contents in hypothyroidism, with thyroxine replacement, and in hyperthyroid rats.","9059964",42]
["Urea","Urea","D014508","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1976,"955380","Effect of thyroid hormones and analogues on ammonia and urea excretion in lata fish (Ophicephalus punctatus).","955380",42]
["Urethane","Urethane","D014520","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"6069782","[Association of thyroid drugs on the teratogenic action of ethylurethan in mice].","6069782",42]
["Urethane","Urethane","D014520","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1975,"804399","Pasma growth hormone responses to thyrotropin-releasing hormone in the urethane-anesthetized rat.","804399",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1952,"12997341","[Effect of thyroxin on blood and urinary uric acid].","12997341",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1962,"13941947","Factors affecting the composition of chicken blood and tissues.","13941947",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14343208","[ORGANIFICATION OF IODIDE BY SHEEP THYROID SECTIONS IN VITRO AND INHIBITORY EFFECT OF XANTHINE, GUANINE AND URIC ACID].","14343208",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C108419,B108419)","v":"Uric Acid"},"Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J108419,K108419)","v":"Thyroxine"},"D013974","Thyroxine",2,2,2015,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q108419,Q108419)","v":"25696010"},"Association between serum free thyroxine (FT4) and uric acid levels in populations without overt thyroid dysfunction.","25696010",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"26619549","[The Association Between Serum Uric Acid and Creatinine in Patients with Hypothyroidism].","26619549",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28085502","Urea, Uric Acid, Prolactin and fT4 Concentrations in Aqueous Humor of Keratoconus Patients.","28085502",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"4285015","Sex difference in rat liver uric acid metabolism.","4285015",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1970,"5517230","[Glucose metabolism, lipid fractions and blood uric acid level following administration of sodium dextro-thyroxine].","5517230",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"5914363","On the effect of the thyroid on the metabolism of free fatty acids and cholesterol in fasting rats.","5914363",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1977,"72533","Blood levels of cyclic AMP, thyroxine, uric acid, certain metabolites and electrolytes under heat-stress and dehydration in the pigeon.","72533",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"7869917","Hyperuricemia in patients with hyperthyroidism due to Graves' disease.","7869917",42]
["Uric Acid","Uric Acid","D014527","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1998,"9491289","Reversible renal insufficiency, hyperuricemia and gouty arthritis in a case of hypothyroidism.","9491289",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1999,"10612341","Long-term treatment of children with epilepsy with valproate or carbamazepine may cause subclinical hypothyroidism.","10612341",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2004,"15009219","Thyroid function in girls with epilepsy with carbamazepine, oxcarbazepine, or valproate monotherapy and after withdrawal of medication.","15009219",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2007,"17326798","Endocrine effects of valproate in adolescent girls with epilepsy.","17326798",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2009,"18978499","Thyroid function in children with epilepsy treated with sodium valproate monotherapy: a prospective study.","18978499",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2009,"18984773","Thyroid hormones in children with epilepsy during long-term administration of carbamazepine and valproate.","18984773",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"1916658","Sodium valproate-induced menstrual disturbance in young women.","1916658",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"22114214","Evaluation of subclinical hypothyroidism in ambulatory children with controlled epilepsy on valproate monotherapy.","22114214",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"22618302","Subclinical hypothyroidism during valproic acid therapy in children and adolescents with epilepsy.","22618302",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"24736121","Evaluation of thyroid hormones in children receiving carbamazepine or valproate: a prospective study.","24736121",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"24977965","Transient hypothyroidism induced by anticonvulsant agents.","24977965",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"25149263","Acute treatment with valproic acid and l-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats.","25149263",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"3929149","Sub-normal serum thyroxine levels associated with carbamazepine and valproic acid treatment.","3929149",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"6792461","Effect of di-N-propylacetic acid (valproic acid) on the TSH response to TRH--a presumptive role for gamma aminobutyric acid.","6792461",42]
["Valproic Acid","Valproic Acid","D014635","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"7782483","The efficacy and safety of divalproex sodium in the treatment of acute mania in adolescents and young adults: an open clinical trial.","7782483",42]
["Vanilmandelic Acid","Vanilmandelic Acid","D014642","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14177089","STUDIES OF PERIODIC CATATONIA. I. BLOOD LEVELS OF PROTEIN-BOUND IODINE AND URINARY EXCRETION OF VANILLYL-MANDELIC ACID IN RELATION TO CLINICAL COURSE.","14177089",42]
["Vanilmandelic Acid","Vanilmandelic Acid","D014642","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"25193009","The effects of seeds with hot and cold temperaments on serum thyroid hormones, corticosterone and urine vanillylmandelic acid concentrations of healthy rats.","25193009",42]
["Vanilmandelic Acid","Vanilmandelic Acid","D014642","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1980,"7399806","The effect of refeeding after semistarvation on catecholamine and thyroid metabolism.","7399806",42]
["Verapamil","Verapamil","D014700","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"11668059","Inhibitory effects of calcium channel blockers on thyroid hormone uptake in neonatal rat cardiomyocytes.","11668059",42]
["Verapamil","Verapamil","D014700","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2004,"15000889","Propranolol and verapamil inhibit mRNA expression of RyR2 and SERCA in L-thyroxin-induced rat ventricular hypertrophy.","15000889",42]
["Verapamil","Verapamil","D014700","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1990,"1715745","Lack of effect of verapamil on diurnal and thyrotropin releasing hormone stimulated thyrotropin levels in man.","1715745",42]
["Verapamil","Verapamil","D014700","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2008,"18251722","Comparative influence of propranolol and verapamil on glycemic control and histamine sensitivity associated with L-thyroxine-induced hyperthyroidism - an experimental study.","18251722",42]
["Verapamil","Verapamil","D014700","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1990,"2142279","The effect of propranolol, verapamil and dantrolene treatment on cardiac hypertrophy, enhanced myocardial contractility and tachycardia in the hyperthyroid rat.","2142279",42]
["Verapamil","Verapamil","D014700","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"2968801","Calcium channel blocker inhibition of the calmodulin-dependent effects of thyroid hormone and milrinone on rabbit myocardial membrane Ca2+-ATPase activity.","2968801",42]
["Verapamil","Verapamil","D014700","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1982,"6819132","Effect of calcium antagonists on thyrotropin and thyroid hormone secretion.","6819132",42]
["vinclozolin","vinclozolin","C025643","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2006,"16489464","Repeated 28-day oral toxicity study of vinclozolin in rats based on the draft protocol for the \"Enhanced OECD Test Guideline No. 407\" to detect endocrine effects.","16489464",42]
["Vincristine","Vincristine","D014750","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1974,"4841717","Physical activity: a possible determinant of vincristine (NSC-67574) neuropathy.","4841717",42]
["vinylidene chloride","vinylidene chloride","C029297","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"1763416","1,1-Dichloroethylene hepatotoxicity: hypothyroidism decreases metabolism and covalent binding but not injury in the rat.","1763416",42]
["vinylidene chloride","vinylidene chloride","C029297","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"3413796","Potentiation of 1,1-dichloroethylene hepatotoxicity: comparative effects of hyperthyroidism and fasting.","3413796",42]
["vinylidene chloride","vinylidene chloride","C029297","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1997,"9310148","Effect of hyperthyroidism on the in vitro metabolism and covalent binding of 1,1-dichloroethylene in rat liver microsomes.","9310148",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1956,"13358795","Effect of L-thyroxine on carotene and vitamin A metabolism in the cow and the chick.","13358795",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2005,"15589659","PCBs and DDT in the serum of juvenile California sea lions: associations with vitamins A and E and thyroid hormones.","15589659",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1999,"10218151","The status of retinoids in women suffering from hyper- and hypothyroidism: interrelationship between vitamin A, beta-carotene and thyroid hormones.","10218151",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"11245393","Relationships between plasma levels of organochlorines, retinol and thyroid hormones from polar bears (Ursus maritimus) at Svalbard.","11245393",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"11482517","Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice.","11482517",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1975,"1167284","[The behavior of glucose, thyroxine, vitamin A, beta-carotene, methionine, and vitamin B12 in the blood of primiparous cattle during puerperium].","1167284",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"11883892","Effects of zinc and vitamin A supplements on plasma levels of thyroid hormones, cholesterol, glucose and egg yolk cholesterol of laying hens.","11883892",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2002,"11997190","Vitamin A modulates the effects of thyroid hormone on UDP-glucuronosyltransferase expression and activity in rat liver.","11997190",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1975,"1216779","[Effect of thyroxine and hydrocortisone on the content of retinol and retinyl palmitate in liver tissue, kidney and blood of rats, loaded with high doses of retinyl acetate].","1216779",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"12357593","Effects of rapeseed-press cake glucosinolates and iodine on the performance, the thyroid gland and the liver vitamin A status of pigs.","12357593",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1952,"12977743","The effect of thyroxine and thiouracil on the composition of milk.  2.  The carotene and vitamin A content.","12977743",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1952,"13018919","[Galactogenic effect of associated vitamin A with thyroxin].","13018919",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1953,"13026022","THYROXINE and thiouracil on milk composition.","13026022",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1953,"13055139","EFFECT of thyroxine and thiouracil on constituents of milk.","13055139",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1953,"13177920","[Therapy of psoriasis according to the indications of Charpy].","13177920",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1954,"13231549","[Treatment of roentgen carcinoma by hypervitaminization with axerophtholen].","13231549",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1955,"13263416","Effect of vitamin A supplements on serum PBI level, and disposal of exogenous thyroxine.","13263416",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1957,"13466935","[Effects of thyroxin and vitamin A on regeneration of the thyroid].","13466935",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1957,"13485035","C14 thyroxine transport in thoracic lymph in rats.","13485035",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1960,"13821589","[Peripheral metabolism of thyroxin in the rat with hypervitaminosis A].","13821589",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1959,"13848044","[Influence of humoral agents upon recovery of sensory and motor function after nerve lesion. 2. Effect of estradiol, thyroxin, dihydrotachysterol, aminoacetonitrile, vitamin A and sodium dihydrogen orthophosphate].","13848044",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14067014","PRECOCIOUS PUBESCENCE--IATROGENIC.","14067014",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14151133","EFFECT OF THYROXINE, THIOURACIL AND AMBIENT TEMPERATURE ON THE UTILIZATION OF VITAMIN A BY VITAMIN A-DEFICIENT RATS.","14151133",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14166650","[THYROID ACTIVITY AND ASCORBEMIA].","14166650",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14176787","[FURTHER STUDIES ON THE SECRETORY ACTIVITY OF THE BRONCHIOLAR EPITHELIUM. A CONTRIBUTION TO THE EXPERIMENTAL PREVENTION OF DISEASES DUE TO DUST INHALATION].","14176787",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14191790","[ACTION OF HORMONES AND VITAMINS ON GROWTH AND DIFFERENTIATION OF BONE CULTIVATED IN VITRO].","14191790",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C108483,B108483)","v":"Vitamin A"},"Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J108483,K108483)","v":"Thyroxine"},"D013974","Thyroxine",2,2,1964,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q108483,Q108483)","v":"14195604"},"STUDIES ON LYSOSOMES. IV. SOLUBILIZATION OF ENZYMES DURING MITOCHONDRIAL SWELLING AND DISRUPTION OF LYSOSOMES BY STREPTOLYSIN S AND OTHER HEMOLYTIC AGENTS.","14195604",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14217777","METABOLIC BASIS OF VISUAL PIGMENT CONVERSION IN METAMORPHOSING RANA CATESBEIANA.","14217777",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1951,"14904410","The effect of thyroxine, thiouracil and stilboestrol on the metabolism of carotene and vitamin A in lactating goats.","14904410",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2005,"15902423","Altered thyroxin and retinoid metabolic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin in aryl hydrocarbon receptor-null mice.","15902423",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1992,"1637200","Inhibition of binding of thyroxin to transthyretin by outdoor and indoor airborne particulate matter and effects on thyroid hormone and vitamin A metabolism in rats.","1637200",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2006,"16499904","Changes in thyroid and vitamin A status in mink fed polyhalogenated-aromatic-hydrocarbon-contaminated carp from the Saginaw River, Michigan, USA.","16499904",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2006,"17042680","Effect of concurrent vitamin A and iodine deficiencies on the thyroid-pituitary axis in rats.","17042680",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1945,"21020728","[Not Available].","21020728",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"23378454","The effect of vitamin A supplementation on thyroid function in premenopausal women.","23378454",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"2441590","Anticonvulsant medication use and circulating levels of total thyroxine, retinol binding protein, and vitamin A in children with delayed cognitive development.","2441590",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"26519832","Snapping Turtles (Chelydra serpentina) from Canadian Areas of Concern across the southern Laurentian Great Lakes: Chlorinated and brominated hydrocarbon contaminants and metabolites in relation to circulating concentrations of thyroxine and vitamin A.","26519832",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2777495","Facilitory role of thyroid hormone in vitamin A uptake in the rat testes.","2777495",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1977,"302061","[Effect of thyroid and adrenal hormones on the course of hypervitaminosis A and D].","302061",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"3094194","Binding of a metabolite of 3,4,3',4'-tetrachlorobiphenyl to transthyretin reduces serum vitamin A transport by inhibiting the formation of the protein complex carrying both retinol and thyroxin.","3094194",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"3101266","[Levels of thyroxine, beta carotene and vitamin A during successful and unsuccessful insemination of heifers].","3101266",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3116724","Effects of vitamin A and/or thyroidectomy on liver microsomal enzymes and their induction in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats.","3116724",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"3933215","Conversion of thyroxine to triiodothyronine in liver biopsy samples of beta-carotene and vitamin-A supplemented dairy cows.","3933215",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"3937314","[Concentrations of thyroxine, beta carotene, vitamin A and pregnancy in heifers after administration of beta carotene].","3937314",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1973,"4196590","Combination of specific antibodies with the human vitamin A-transporting protein complex.","4196590",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1974,"4131753","The hypercarotenemia in anorexia nervosa: a comparison of vitamin A and carotene levels in various forms of menstrual dysfunction and cachexia.","4131753",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1978,"415832","The inter-relationship of thyroid hormones, vitamin A and their binding proteins following acute stress.","415832",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"4164549","Effect of dietary protein level and thyroxine on vitamin A absorption and on plasma proteins in chicks.","4164549",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1974,"4215098","[Metabolism of fat soluble vitamins--retinol binding protein (author's transl)].","4215098",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1972,"4636121","Visual pigment changes in salmonid fishes in response to exogenous L-thyroxine, bovine TSH and 3-dehydroretinol.","4636121",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1972,"4644618","[Retention of serum copper content with an oral vitamin A load].","4644618",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1973,"4708098","Studies on the transport and cellular distribution of vitamin A in normal and vitamin A-deficient rats with special reference to the vitamin A-binding plasma protein.","4708098",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1973,"4718739","The interaction of human plasma retinol-binding protein and prealbumin.","4718739",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1969,"4978316","The interaction of thyroxine with human plasma prealbumin and with the prealbumin-retinol-binding protein complex.","4978316",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1970,"4985906","Studies on the protein-protein and protein-ligand interactions involved in retinol transport in plasma.","4985906",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1972,"5046816","Circular dichroic studies of human plasma retinol-binding protein and prealbumin.","5046816",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1979,"510424","Scotopic visual pigment composition in the retinas and vitamins A in the pigment epithelium of the goldfish.","510424",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"5656701","Influence of different forms of vitamin A, thyroxine, and thiouracil on carotenoid utilization by chicks.","5656701",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1978,"566568","Thyroidal control of heaptic release and metabolism of vitamin A.","566568",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"5840972","The significance of alterations in serum lipids in thyroid dysfunction. I. The relation between serum lipoproteins, carotenoids and vitamin A in hypothyroidism and thyrotoxicosis.","5840972",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"5939291","Effect of dietary protein level and thyroxine on vitamin A depletion from liver in chicks.","5939291",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"5946565","Interacting effects of thyroid activity and dietary level of vitamin A on erythrocyte fragility in the chicken.","5946565",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1966,"6011842","[Peculiarities in the injuries of palatal-anlage in mammal embryos in the case of meternal A hypervitaminosis].","6011842",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"6061567","The effect of thyroid status and restriction of dietary protein on survival of vitamin A deprived chicks.","6061567",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"6082318","Effects of thyroxine, vitamin A and HeLa cells on differentiation of aggregates of dissociated embryonic chick skin cells in vitro.","6082318",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1982,"6175287","Vitamin A and beta-carotene content of seminal fluid and sperm of normospermic and oligozoospermic men.","6175287",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6242278","Effect of thyrotropin (TSH) treatment on the vitamins A and E and lipid-peroxide status of domestic fowl.","6242278",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1980,"6244741","Effect of vitamin A on the hypothalamo-pituitary-thyroid axis.","6244741",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"7196691","The interrelationship of thyroid hormones with vitamin A and zinc nutritional status in patients with chronic hepatic and gastrointestinal disorders.","7196691",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1980,"7420203","Influence of supplemental dietary vitamin A on the reproductive performance of iodine-toxic rats.","7420203",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1980,"7465810","The effects of dexamethasone (DXM) and vitamin A on the growth and metamorphosis of gamma irradiated thyroxine induced Bufo melanostictus tadpoles.","7465810",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1994,"8202959","Effects of outdoor and indoor airborne particulate matter on thyroid hormone and vitamin A metabolism.","8202959",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1994,"8207753","Effects of fasting and 3,3',4,4',5,5'-hexabromobiphenyl on plasma transport of thyroxine and retinol: fasting reverses elevation of retinol.","8207753",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8384721","Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone.","8384721",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8478982","Effects on thyroid hormone metabolism and depletion of lung vitamin A in rats by airborne particulate matter.","8478982",42]
["Vitamin A","Vitamin A","D014801","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1996,"8616805","Promoting effect of large amounts of vitamin A on cell proliferation of thyroid proliferative lesions induced by simultaneous treatment with thiourea.","8616805",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1955,"13329112","[Betain-homocysteine transmethylase activity and vitamin B12 content of the liver in rat in experimental thyrotoxicosis].","13329112",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1962,"13877667","[Determination, in the plasma, of substances of biological importance by means of the tracer use of radioactive compounds].","13877667",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1976,"1069687","Thyroid hormone-vitamin treatment: a dental and medical evaluation.","1069687",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1975,"1167284","[The behavior of glucose, thyroxine, vitamin A, beta-carotene, methionine, and vitamin B12 in the blood of primiparous cattle during puerperium].","1167284",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1953,"13077015","[Value of the addition of thyroxin to vitamin B12 in the treatment of certain patients with pernicious anemia].","13077015",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1954,"13171148","[Vitamin B12 content of the liver of thyroxinated rats].","13171148",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1955,"13239851","[Effect of thyroxine on the lipotrophic activity of vitamin B12].","13239851",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1958,"13607672","[Hepatic desoxyribonucleic acid &amp; ribonucleic acid in the rat on steatogenous diet &amp; treated with vitamin B12 &amp; thyroxin].","13607672",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14087059","[DRUGS LOWERING THE CHOLESTEROL LEVEL IN THE BLOOD].","14087059",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14109309","[THE INFLUENCE OF VITAMIN B 12 ON THE CALORIGENIC EFFECT OF THYROXINE].","14109309",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14134708","APPLICATION OF THE PROPERTY OF PROTEIN-BINDING TO THE ASSAY OF MINUTE QUANTITIES OF HORMONES AND OTHER SUBSTANCES.","14134708",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14243056","HEREDITARY OROTIC ACIDURIA AND MEGALOBLASTIC ANAEMIA: A SECOND CASE, WITH RESPONSE TO URIDINE.","14243056",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14341829","ADDISON'S DISEASE WITH VITILIGO, ADDISONIAN ANAEMIA, PRIMARY HYPOTHROIDISM AND DIABETES MELLITUS.","14341829",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1950,"14795272","The protective action of vitamin B12 against the toxicity of DL-thyroxine.","14795272",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C108547,B108547)","v":"Vitamin B 12"},"Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J108547,K108547)","v":"Thyroxine"},"D013974","Thyroxine",2,2,1950,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q108547,Q108547)","v":"14817584"},"[Therapeutic effect of thyroxin in a case of Biermer anemia treated with vitamin B12].","14817584",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2007,"17464093","Homocysteine, folate and cobalamin levels in hypothyroid women before and after treatment.","17464093",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2009,"20041361","Homocysteine, folate, and cobalamin levels in hyperthyroid women before and after treatment.","20041361",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2011,"21265849","The prevalence of hypocobalaminaemia in cats with spontaneous hyperthyroidism.","21265849",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2741921","Serum and red cell folate and serum vitamin B12 levels in hyperthyroidism.","2741921",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"4056070","Importance of low serum vitamin B12 and red cell folate concentrations in elderly hospital inpatients.","4056070",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"4299176","[The Achilles reflexogram and its changes induced by vitamin B 12 in obesity].","4299176",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1968,"5660125","[Change in folic acid metabolism after administration of vitamin B-12 antimetabolites and thyroid gland hormones].","5660125",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1980,"6972186","Nutritional interactions of vitamin B12, folic acid, and thyroxine.","6972186",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8217401","[Circadian rhythm disturbance after radiotherapy for brain tumor in infantile period--clinical effect of L-thyroxine and vitamin B12].","8217401",42]
["Vitamin B 12","Vitamin B 12","D014805","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1977,"912873","Use of protein containing magnetic microparticles in radioassays.","912873",42]
["Vitamin B 6","Vitamin B 6","D025101","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1959,"13672186","Pyridoxine and pyridoxal phosphate concentrations in the liver and heart of thyroxinized animals.","13672186",42]
["Vitamin B 6","Vitamin B 6","D025101","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1959,"13807361","[Effect of the treatment with thyroxin on certain enzymatic systems dependent on vitamin B6].","13807361",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1956,"13359868","[Late rachitism not reacting to vitamin D or to calcium phosphates; cure with thyroxin].","13359868",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1956,"13396143","Periarteritis and other forms of necrotising angeitis produced by vitamin D in thyroxinised rats with an assessment of the aetiology of those vascular lesions.","13396143",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1978,"154950","[Immunocytological studies of C cells with anti-calcitonin or antisomatostatin immunoserums in rats treated with vitamin D, thyroxine or benzyl-thiouracil].","154950",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"11440875","Thyroxine and vitamin D in the gorgonian Leptogorgia virgulata.","11440875",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14130832","HORMONAL DISTURBANCES IN THE ELDERLY.","14130832",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14191790","[ACTION OF HORMONES AND VITAMINS ON GROWTH AND DIFFERENTIATION OF BONE CULTIVATED IN VITRO].","14191790",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2004,"15175591","Hypovitaminosis D in acutely injured pediatric burn patients.","15175591",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2007,"17849744","Prevalence of vitamin D insufficiency in obese children and adolescents.","17849744",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2009,"19203420","Prevalence of vitamin D deficiency and its relationship with thyroid autoimmunity in Asian Indians: a community-based survey.","19203420",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2009,"19429246","Effects of 3,3',4,4',5-pentachlorobiphenyl (PCB126) on vertebral bone mineralization and on thyroxin and vitamin D levels in Sprague-Dawley rats.","19429246",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"22547366","Serum vitamin D levels are decreased and associated with thyroid volume in female patients with newly onset Graves' disease.","22547366",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"22876540","Vitamin D status in children with Hashimoto thyroiditis.","22876540",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"24809139","4 important blood tests for women--and what the results mean.  Here's why every woman needs to know her numbers.","24809139",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"25370319","Low Vitamin D Status is Associated with Increased Thyrotropin-Receptor Antibody Titer in Graves Disease.","25370319",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"25395280","Serum 25-Hydroxyvitamin D and Parathyroid Hormone Levels in Non-Lactating Women with Post-Partum Thyroiditis: The Effect of L-Thyroxine Treatment.","25395280",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2604508","[Prophylaxis of vitamin D deficiency in hypothyroidism in the newborn infant].","2604508",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2016,"26433740","Low 25 (OH) vitamin D levels are associated with autoimmune thyroid disease in polycystic ovary syndrome.","26433740",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2016,"26757834","The effect of vitamin D on thyroid autoimmunity in non-lactating women with postpartum thyroiditis.","26757834",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2016,"27086659","Regulatory T Cells and Vitamin D Status in Children with Chronic Autoimmune Thyroiditis.","27086659",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2016,"27571093","25 Hydroxyvitamin D Deficiency and Its Relationship to Autoimmune Thyroid Disease in the Elderly.","27571093",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28073128","The Effect of Vitamin D on Thyroid Autoimmunity in Levothyroxine-Treated Women with Hashimoto's Thyroiditis and Normal Vitamin D Status.","28073128",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"3490559","Hypercalcemia in infants with congenital hypothyroidism and its relation to vitamin D and thyroid hormones.","3490559",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"4235646","[Study of the cytologic origin of thyrocalcitonin in rats with hypervitaminosis D].","4235646",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1974,"4611226","Ultrastructural evaluation of the effects of calcitonin on bone in thyroparathyroidectomized rats administered vitamin D.","4611226",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1969,"4975507","[Effects of hypervitaminosis D on the level of magnesium in the heart, kidney, and skeletal muscle of rats. Incidence of thyroxine surcharge and radiothyroidectomy].","4975507",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1982,"6981469","Vitamin D metabolism in hyperthyroidism.","6981469",42]
["Vitamin D","Vitamin D","D014807","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8406326","Effect of short-term hyperthyroxinemia on vitamin D metabolism in congenital hypothyroidism.","8406326",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1999,"10382867","Palm vitamin E improves bone metabolism and survival rate in thyrotoxic rats.","10382867",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2000,"10613777","Plasma thyroxine and cholesterol concentrations of miniature pigs are influenced by thermally oxidized dietary lipids.","10613777",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1999,"10735112","Serum luteinizing hormone, testosterone, and thyroxine and growth responses of ram lambs fed locoweed (Oxytropis sericea) and treated with vitamin E/selenium.","10735112",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2002,"11834455","Cell necrosis and apoptosis are differentially regulated during goitre development and iodine-induced involution.","11834455",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2002,"11881797","Effects of vitamin C and vitamin E on lipid peroxidation, blood serum metabolites, and mineral concentrations of laying hens reared at high ambient temperature.","11881797",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2002,"11944200","Effects of vitamin C and vitamin E on lipid peroxidation status, serum hormone, metabolite, and mineral concentrations of Japanese quails reared under heat stress (34 degrees C).","11944200",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,3,2002,"12042446","Thermally oxidized dietary fats increase plasma thyroxine concentrations in rats irrespective of the vitamin E and selenium supply.","12042446",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2002,"12587721","Effect of antioxidants (vitamin C, E and turmeric extract) on methimazole induced hypothyroidism in rats.","12587721",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1962,"13941947","Factors affecting the composition of chicken blood and tissues.","13941947",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1950,"15431641","[Effect of vitamin E on the metabolism of muscles treated with thyroxin].","15431641",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2005,"16298753","Studies on the protective role of vitamin C and E against polychlorinated biphenyl (Aroclor 1254)--induced oxidative damage in Leydig cells.","16298753",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"1781930","Damage to hepatic thyroxine 5'-deiodination induced by pathogenic factors of Keshan disease and the preventive effects of selenium and vitamin E.","1781930",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2008,"18377885","Alleviation of enhanced oxidative stress and oxygen consumption of L-thyroxine induced hyperthyroid rat liver mitochondria by vitamin E and curcumin.","18377885",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2008,"18723006","Protective effects of vitamin E and curcumin on L-thyroxine-induced rat testicular oxidative stress.","18723006",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2010,"19914224","Expression of hepatic antioxidant genes in l-thyroxine-induced hyperthyroid rats: regulation by vitamin E and curcumin.","19914224",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1947,"20245946","[Not Available].","20245946",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2011,"20574713","Regulation of expression of antioxidant enzymes by vitamin E and curcumin in L-thyroxine-induced oxidative stress in rat renal cortex.","20574713",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1990,"2080138","[Vitamin E and malondialdehyde in the blood serum of thyrotoxicosis patients].","2080138",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2013,"23001627","Levothyroxine replacement therapy with vitamin E supplementation prevents oxidative stress and cognitive deficit in experimental hypothyroidism.","23001627",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"25702296","Levothyroxine replacement therapy with vitamin E supplementation prevents the oxidative stress and apoptosis in hippocampus of hypothyroid rats.","25702296",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2632676","Vitamin E protects against thyroxine-induced acceleration of lipid peroxidation in cardiac and skeletal muscles in rats.","2632676",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28213641","Role of levothyroxine and vitamin E supplementation in the treatment of oxidative stress-induced injury and apoptosis of myocardial cells in hypothyroid rats.","28213641",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3442483","[Vitamin E requirement of chicks and young hens].","3442483",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1974,"4361496","Vitamin E: relationship to thyroxine in man.","4361496",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C108611,B108611)","v":"Vitamin E"},"Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J108611,K108611)","v":"Thyroxine"},"D013974","Thyroxine",2,2,1974,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q108611,Q108611)","v":"4464103"},"[Alpha-tocopherol content in the brain and blood of rats with experimental thyrotoxicosis].","4464103",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1973,"4749913","Investigations of the relationship between thyroid function and alpha-tocopherol concentration of serum and in some organs of the rat.","4749913",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1974,"4836809","[Effect of thyroxine intoxication in animals on the vitamin E level in the myocardium].","4836809",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1972,"5069957","[Action of an antioxidant substance (alpha-tocopherol) on the myocardium of rats treated with thyroxine].","5069957",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1970,"5525962","[Effect of alpha-tocopherol, adenosine triphosphoric acid, nerobolil and apilac on the oxidative phosphorylation in the brain hemispheres in thyroxine poisoning].","5525962",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6242278","Effect of thyrotropin (TSH) treatment on the vitamins A and E and lipid-peroxide status of domestic fowl.","6242278",42]
["Vitamin E","Vitamin E","D014810","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1996,"8674204","Lipid peroxidation and vitamin E supplementation in experimental hyperthyroidism.","8674204",42]
["Vitamin K","Vitamin K","D014812","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1953,"13055139","EFFECT of thyroxine and thiouracil on constituents of milk.","13055139",42]
["Vitamin K","Vitamin K","D014812","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1957,"13429811","[Oxidative phosphorylation and its hormonal stimulation].","13429811",42]
["Vitamin K","Vitamin K","D014812","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14067014","PRECOCIOUS PUBESCENCE--IATROGENIC.","14067014",42]
["Vitamin K","Vitamin K","D014812","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14146921","PLACENTAL TRANSMISSION OF DRUGS.","14146921",42]
["Vitamin K","Vitamin K","D014812","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14191790","[ACTION OF HORMONES AND VITAMINS ON GROWTH AND DIFFERENTIATION OF BONE CULTIVATED IN VITRO].","14191790",42]
["Vitamin K","Vitamin K","D014812","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1945,"21020728","[Not Available].","21020728",42]
["Vitamin K","Vitamin K","D014812","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28612237","Assessment of the Impact of L-Thyroxine Therapy on Bleeding Risk in Patients Receiving Vitamin K Antagonists.","28612237",42]
["Vitamin K","Vitamin K","D014812","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1973,"4581196","[Drug interactions with vitamin K antagonists].","4581196",42]
["Vitamin K","Vitamin K","D014812","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"7495070","Growth hormone deficiency impairs blood clotting and reduces factor VII coagulant activity in rat.","7495070",42]
["vorinostat","vorinostat","C111237","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2016,"27267120","SAHA-induced loss of tumor suppressor Pten gene promotes thyroid carcinogenesis in a mouse model.","27267120",42]
["vorozole","vorozole","C060523","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,3,1998,"9532425","In ovo treatment with an aromatase inhibitor masculinizes postnatal hormone levels, abdominal fat pad content, and GH pulsatility in broiler chickens.","9532425",42]
["VX","VX","C009680","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,3,2008,"18614271","An animal model to study health effects during continuous low-dose exposure to the nerve agent VX.","18614271",42]
["W 7","W 7","C017967","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"1887879","Effects of calmodulin antagonists on hydrogen-translocating shuttles in perfused rat liver.","1887879",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2002,"12239881","[Bleeding problems of a patient with hypothyroidism].","12239881",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1962,"13934487","[Provocation and voluntary aggravation of various pathologic states in a young psychopath; medicolegal aspects].","13934487",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1992,"1429970","Characterization of thyroxine-albumin binding using high-performance affinity chromatography. I. Interactions at the warfarin and indole sites of albumin.","1429970",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1962,"15445906","Effect of sodium dextrothyroxine in patients receiving anticoagulants.","15445906",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2012,"23093318","A population-based assessment of the drug interaction between levothyroxine and warfarin.","23093318",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"2434073","Drug-binding properties of rat alpha-foetoprotein. Specificities of the phenylbutazone-binding and warfarin-binding sites.","2434073",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"24913218","An evaluation of the potential drug interaction between warfarin and levothyroxine.","24913218",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2595433","Hypothyroidism: effect on warfarin anticoagulation.","2595433",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3623421","Lack of effect of warfarin on L-thyroxine metabolism.","3623421",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1967,"6059285","Change in receptor site affinity: a proposed explanation for the potentiating effect of D-thyroxine on the anticoagulant response to warfarin.","6059285",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1982,"6176242","Inhibition by coumadin anticoagulants of enzymatic outer ring monodeiodination of iodothyronines.","6176242",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6697623","Potentiation of oral anticoagulant effect by L-thyroxine.","6697623",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"7795810","Characterization of thyroxine-albumin binding using high-performance affinity chromatography. II. Comparison of the binding of thyroxine, triiodothyronines and related compounds at the warfarin and indole sites of human serum albumin.","7795810",42]
["Warfarin","Warfarin","D014859","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,3,1999,"9926737","Potentiation of warfarin sodium by amiodarone-induced thyrotoxicosis.","9926737",42]
["Waste Water","Waste Water","D062065","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2014,"24273037","Biological responses of marine flatfish exposed to municipal wastewater effluent.","24273037",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1979,"119801","Hypopituitarism with water intoxication and coma: favorable outcome following early treatment.","119801",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1956,"13317932","The coupling of body weight to water metabolism in the female baboon (Papio ursinus) with special reference to the relationship of thyroxin to body weight.","13317932",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1961,"13684437","[Neurosecretion in the water turtle, Emys leprosa Schw., after thyroidectomy and thyroxin injections].","13684437",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1962,"13916005","Effect of thyroxine on radioiodine metabolism by the thyroid gland of goldfish, Carassius auratus L., in fresh and iodine-enriched water.","13916005",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14112257","THE EFFECT OF THYROID HORMONES ON WATER PERMEABILITY OF THE ISOLATED BLADDER OF THE TOAD BUFO BUFO.","14112257",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14196579","FURTHER STUDIES ON THE EFFECT OF RADIO FREQUENCY HYPOTHALAMIC LESIONS ON LACTATION AND WATER METABOLISM.","14196579",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14223279","EFFECT OF TOXIC DOSES OF L-THYROXINE ON TISSUE WATER, ELECTROLYTES AND PLASMA PROTEIN IN RATS.","14223279",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14266252","WATER EXTRUSION IN ISOLATED SUBCELLULAR FRACTIONS. 3. THE IMPORTANCE OF PHOSPHOLIPIDS IN THE ME2+-EDTA DEPENDENT REACTION.","14266252",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14279726","EFFECT OF THYROXINE ON THE ISOLATED RAT INTESTINE.","14279726",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14284317","THE INFLUENCE OF THYROID HORMONES ON NORMAL RAT-LIVER MITOCHONDRIA. 3. THYROXINE-INDUCED SWELLING IN PRETREATED MITOCHONDRIA.","14284317",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1955,"14391330","Chloride and water changes after scalding in hypophysectomized and hormone treated rats.","14391330",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2015,"25372987","An insight to the conserved water mediated dynamics of catalytic His88 and its recognition to thyroxin and RBP binding residues in human transthyretin.","25372987",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1970,"4189879","Antidiuretic effect and complications of chlorpropamide therapy in diabetes insipidus.","4189879",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1973,"4707697","The influence of gastrin on the fecal and urinary excretion of water, calcium, magnesium, and inorganic phosphorus in sheep.","4707697",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1980,"7457015","[Influence of drinking water supply on iodine metabolism by experimental animals].","7457015",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1994,"7834996","Restoration by corticosteroids of the hyperaldosteronism in hyponatraemic rats with panhypopituitarism.","7834996",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1994,"7951559","Effects of an acute water load on plasma ANP and AVP, and renal water handling in hypothyroidism: comparison of before and after L-thyroxine treatment.","7951559",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8499764","Antithyroid and goitrogenic effects of coal-water extracts from iodine-sufficient goiter areas.","8499764",42]
["Water","Water","D014867","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1997,"9000462","Influence of thyroid status on water metabolism and survival of normal and dehydrated desert rodents Meriones libycus.","9000462",42]
["Wy 13876","Wy 13876","C012139","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"7256773","Biotransformation of the immunomodulator, 3-(p-chlorophenyl)-2,3-dihydro-3-hydroxythiazolo[3,2a]benzimidazole-2-acetic acid, and its relationship to thyroid toxicity.","7256773",42]
["Xanthine","Xanthine","D019820","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"14343208","[ORGANIFICATION OF IODIDE BY SHEEP THYROID SECTIONS IN VITRO AND INHIBITORY EFFECT OF XANTHINE, GUANINE AND URIC ACID].","14343208",42]
["xanthohumol","xanthohumol","C104536","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2010,"20461738","Xanthohumol, a prenylated chalcone from hops, modulates hepatic expression of genes involved in thyroid hormone distribution and metabolism.","20461738",42]
["XM-50 Amicon","XM-50 Amicon","C030841","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1981,"7242859","Pituitary hollow fiber units in the dwarf mouse.","7242859",42]
["Xylazine","Xylazine","D014991","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"11285197","Promoting effects of xylazine on development of thyroid tumors in rats initiated with N-bis(2-hydroxypropyl)nitrosamine and the mechanism of action.","11285197",42]
["Xylazine","Xylazine","D014991","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2003,"12767697","Dose-threshold for thyroid tumor-promoting effects of xylazine in rats.","12767697",42]
["Xylazine","Xylazine","D014991","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1989,"2565187","The effect of yohimbine on plasma levels of T3, T4 and cortisol in xylazine-immobilized white-tailed deer.","2565187",42]
["xylooligosaccharide","xylooligosaccharide","C570991","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2013,"24082401","Effect of a straw-derived xylooligosaccharide on broiler growth performance, endocrine metabolism, and immune response.","24082401",42]
["Xylose","Xylose","D014994","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1963,"14015734","Utilization and excretion of D-xylose in thyroxine-treated rats.","14015734",42]
["Xylose","Xylose","D014994","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1961,"14472693","[Effect of thyroxin on the volume of endocellular distribution of D(plus) xylose and sodium in rat epididymal adipose tissue].","14472693",42]
[{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & C108675,B108675)","v":"Yohimbine"},"Yohimbine","D015016","3_KE",281,3,"Thyroxin (T4) in serum","Decreased",{"$f":"HYPERLINK(\"https://meshb.nlm.nih.gov/record/ui?ui=\" & J108675,K108675)","v":"Thyroxine"},"D013974","Thyroxine",2,2,1989,{"$f":"HYPERLINK(\"https://www.ncbi.nlm.nih.gov/pubmed/\" & Q108675,Q108675)","v":"2565187"},"The effect of yohimbine on plasma levels of T3, T4 and cortisol in xylazine-immobilized white-tailed deer.","2565187",42]
["Zearalenone","Zearalenone","D015025","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28365492","Interaction of mycotoxin zearalenone with human serum albumin.","28365492",42]
["Zeranol","Zeranol","D015029","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3312138","Influence of frame size and zeranol on growth, compositional growth and plasma hormone characteristics.","3312138",42]
["Zeranol","Zeranol","D015029","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"3531136","Implanting young bulls with zeranol from birth to four slaughter ages: III. Growth performance and endocrine aspects.","3531136",42]
["Zimeldine","Zimeldine","D015031","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1984,"6234610","The role of serotonin (5-HT) in the control of TSH and prolactin release in euthyroid subjects as assessed by the administration of ketanserin (5-HT2 antagonist) and zimelidine (5-HT re-uptake inhibitor).","6234610",42]
["zinc chloride","zinc chloride","C016837","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2001,"11288928","Effect of glutathione (GSH) depletion on the serum levels of triiodothyronine (T3), thyroxine (T4), and T3/T4 ratio in allyl alcohol-treated male rats and possible protection with zinc.","11288928",42]
["zinc chloride","zinc chloride","C016837","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1986,"3713445","Substrate specificity of iodothyronine 5'-deiodinase in rat liver homogenates and its requirements of divalent cations in vitro.","3713445",42]
["Zinc Sulfate","Zinc Sulfate","D019287","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1999,"10451566","[Zinc inhibits the in vitro conversion of thyroxine to triiodothyronine in brown adipose issue].","10451566",42]
["Zinc Sulfate","Zinc Sulfate","D019287","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2002,"12061240","Zinc supplementation decreases total thyroid hormone concentration in small ruminants.","12061240",42]
["Zinc Sulfate","Zinc Sulfate","D019287","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1991,"1657339","[Zinc sulfate and thyroxine treatment on the obese patients].","1657339",42]
["Zinc Sulfate","Zinc Sulfate","D019287","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1987,"3448618","Effects of zinc and thyroxine treatment on dietary-obese mice.","3448618",42]
["Zinc Sulfate","Zinc Sulfate","D019287","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8019155","Modulation of the neuroendocrine system and immune functions by zinc supplementation in children with Down's syndrome.","8019155",42]
["Zinc Sulfate","Zinc Sulfate","D019287","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1995,"8580517","Changes induced by zinc on thyroxine deiodination by rat liver in vivo and in vitro.","8580517",42]
["Zineb","Zineb","D015038","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2017,"28237669","Disruption of the hypothalamic-pituitary-thyroid axis on co-exposures to dithiocarbamate and neonicotinoid pesticides: Study in a wildlife bird, Amandava amandava.","28237669",42]
["Zineb","Zineb","D015038","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1988,"3358011","Failure of phenobarbitone to potentiate the adverse effects of two ethylene-bis-dithiocarbamate (EBDC) fungicides.","3358011",42]
["Zineb","Zineb","D015038","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1985,"3938269","The effect of maneb, zineb, and ethylenethiourea on the humoral activity of the pituitary-thyroid axis in rat.","3938269",42]
["Zineb","Zineb","D015038","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1993,"8406605","Effect of oral administration of fungicide-mancozeb on thyroid gland of rat.","8406605",42]
["Zineb","Zineb","D015038","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1996,"8661871","Acute effects of low doses of zineb and ethylenethiourea on thyroid function in the male rat.","8661871",42]
["Zineb","Zineb","D015038","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,3,1997,"9418944","Studies on rat thyroid after oral administration of mancozeb: morphological and biochemical evaluations.","9418944",42]
["zoledronic acid","zoledronic acid","C088658","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,2011,"21891972","Transient changes in thyroid functions tests after zoledronic acid infusion.","21891972",42]
["zolpidem","zolpidem","C049109","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1996,"8784082","Progressive elevation of plasma thyrotropin during adaptation to simulated jet lag: effects of treatment with bright light or zolpidem.","8784082",42]
["Zoxazolamine","Zoxazolamine","D015049","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1961,"13695067","Contrasting effects of thyroxin on zoxazolamine and hexobarbital metabolism.","13695067",42]
["Zoxazolamine","Zoxazolamine","D015049","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1965,"4285416","Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes.","4285416",42]
["Zoxazolamine","Zoxazolamine","D015049","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1969,"5306221","Differences in the oxidative metabolism of drugs by liver microsomes.","5306221",42]
["Zymosan","Zymosan","D015054","3_KE",281,3,"Thyroxin (T4) in serum","Decreased","Thyroxine","D013974","Thyroxine",2,2,1964,"14117433","THYROID FUNCTION AND KIDNEY MURAMIDASE.","14117433",42]
[null,"Colestipol","D003084","2_KE",277,2,"Thyroid hormone synthesis","Decreased",null,"D013963","Thyroid Hormones",1,2,1998,"9972670","Role of colestipol in the treatment of hyperthyroidism.","9972670",42]