{"text_format":"1","workbook":"xlsx","n_sheets":4,"sheets":["ReadMe","Overview","Detail","CuratedList"],"not_rendered":{"charts":0,"images":0,"macros":1,"external_links":0,"defined_names":3,"comments":1,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"ReadMe","index":0,"n_rows":2,"n_cols":1,"rows_kept":2,"cut":false,"hidden":false,"merged":[]}
["Excel File S1. PubMed articles of ToxRefDB chemicals by male reproductive endpoints."]
["Read Me"]

{"sheet":"Overview","index":1,"n_rows":92,"n_cols":57,"rows_kept":92,"cut":false,"hidden":false,"merged":[[1,1,1,55]]}
["Overview"]
[null,"Article Counts"]
[null,"Cryptorchidism","Urogenital Abnormalities","Hypospadias","46, XX Disorders of Sex Development","46, XY Disorders of Sex Development","Acrosome","Adrenal Hyperplasia, Congenital","Adrenogenital Syndrome","Androgen-Insensitivity Syndrome","Bladder Exstrophy","Blood-Testis Barrier","Bulbourethral Glands","Disorders of Sex Development","Ejaculatory Ducts","Epididymis","Foreskin","Frasier Syndrome","Freemartinism","Genital Neoplasms, Male","Genitalia, Male","Gonadal Dysgenesis","Gonadal Dysgenesis, 46,XY","Gonadal Dysgenesis, Mixed","Hyperandrogenism","Klinefelter Syndrome","Leydig Cell Tumor","Leydig Cells","Penis","Prostate","Prostatic Neoplasms","Rete Testis","Scrotum","Seminal Vesicles","Seminiferous Epithelium","Seminiferous Tubules","Sertoli Cell Tumor","Sertoli Cells","Sertoli-Leydig Cell Tumor","Sexual Infantilism","Sperm Count","Sperm Head","Sperm Maturation","Sperm Motility","Sperm Tail","Spermatic Cord","Spermatids","Spermatocytes","Spermatogenesis","Spermatogonia","Spermatozoa","Testicular Neoplasms","Testis","Turner Syndrome","Urethra","Vas Deferens","Chemical (hyperlinked)"]
["Chemical (hyperlinked)",{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & B3,B3)","v":"Cryptorchidism"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & C3,C3)","v":"Urogenital Abnormalities"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & D3,D3)","v":"Hypospadias"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & E3,E3)","v":"46, XX Disorders of Sex Development"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & F3,F3)","v":"46, XY Disorders of Sex Development"},"Acrosome","Adrenal Hyperplasia, Congenital","Adrenogenital Syndrome","Androgen-Insensitivity Syndrome","Bladder Exstrophy","Blood-Testis Barrier","Bulbourethral Glands","Disorders of Sex Development","Ejaculatory Ducts","Epididymis","Foreskin","Frasier Syndrome",{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & S3,S3)","v":"Freemartinism"},"Genital Neoplasms, Male","Genitalia, Male","Gonadal Dysgenesis","Gonadal Dysgenesis, 46,XY","Gonadal Dysgenesis, Mixed","Hyperandrogenism","Klinefelter Syndrome","Leydig Cell Tumor","Leydig Cells","Penis","Prostate","Prostatic Neoplasms","Rete Testis","Scrotum","Seminal Vesicles","Seminiferous Epithelium","Seminiferous Tubules","Sertoli Cell Tumor","Sertoli Cells","Sertoli-Leydig Cell Tumor","Sexual Infantilism","Sperm Count","Sperm Head","Sperm Maturation","Sperm Motility","Sperm Tail","Spermatic Cord","Spermatids","Spermatocytes","Spermatogenesis","Spermatogonia","Spermatozoa","Testicular Neoplasms","Testis","Turner Syndrome","Urethra","Vas Deferens","Chemical (hyperlinked)"]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & BE5,BE5)","v":"((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)"},0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,1,0,0,0,"((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)"]
["1,2,3-trichloropropane",0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,"1,2,3-trichloropropane"]
["1,2,4,5-tetrachlorobenzene",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,"1,2,4,5-tetrachlorobenzene"]
["2,4-Dichlorophenoxyacetic Acid",0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,2,0,1,0,0,0,0,0,0,0,1,0,0,1,0,0,1,0,0,0,0,1,2,6,0,4,0,0,0,"2,4-Dichlorophenoxyacetic Acid"]
["2,4-dinitrotoluene",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,2,0,1,0,1,0,0,0,"2,4-dinitrotoluene"]
["2-butanone oxime",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,"2-butanone oxime"]
["2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,"2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide"]
["2-ethylhexanoic acid",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,"2-ethylhexanoic acid"]
["2-Methyl-4-chlorophenoxyacetic Acid",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,2,0,0,0,"2-Methyl-4-chlorophenoxyacetic Acid"]
["4-nitrobenzoic acid",0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,"4-nitrobenzoic acid"]
["4-octylphenol",0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,1,0,2,0,0,0,0,0,0,0,1,0,0,2,0,0,1,0,0,0,0,2,0,1,0,6,0,0,0,"4-octylphenol"]
["Acetaminophen",5,1,2,0,0,0,1,0,0,2,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,1,1,3,0,5,0,6,0,0,1,"Acetaminophen"]
["acetamiprid",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,"acetamiprid"]
["acetochlor",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,"acetochlor"]
["Acrylamide",0,0,0,0,0,0,0,0,0,0,0,0,0,0,7,0,0,0,0,1,0,0,0,0,0,0,3,0,1,0,0,0,0,0,2,0,0,0,0,5,3,0,6,1,0,8,5,13,3,23,0,11,0,0,1,"Acrylamide"]
["alachlor",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,"alachlor"]
["Aldrin",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,2,0,0,0,"Aldrin"]
["Aspirin",3,0,1,0,0,0,1,1,0,0,0,0,0,0,2,0,0,0,0,2,0,0,0,0,0,0,1,0,1,0,0,0,2,0,1,0,3,0,0,3,0,0,3,0,0,2,3,7,1,6,0,12,0,0,0,"Aspirin"]
["Atrazine",0,0,1,0,0,0,0,0,0,0,0,0,10,0,4,1,0,0,0,7,1,0,0,0,0,0,0,0,3,0,0,0,0,0,0,0,1,0,0,2,0,0,1,0,0,1,1,3,0,8,0,15,0,0,0,"Atrazine"]
["bifenthrin",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,"bifenthrin"]
["bisphenol A",2,0,2,0,0,2,0,0,0,0,1,0,4,0,12,2,0,0,0,11,0,0,0,1,0,0,6,3,21,5,0,0,9,1,6,0,6,0,0,20,0,0,16,0,0,2,1,22,2,31,0,48,0,1,0,"bisphenol A"]
["boric acid",0,0,0,0,0,0,0,0,0,0,0,0,0,0,5,0,0,0,0,0,0,0,0,0,0,0,0,0,3,0,0,0,3,2,1,0,0,0,0,4,0,0,3,0,0,0,0,7,0,5,0,10,0,0,0,"boric acid"]
["butachlor",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,"butachlor"]
["carbendazim",0,0,0,0,0,2,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3,0,3,0,0,4,1,0,3,0,0,5,2,11,2,11,0,14,0,0,0,"carbendazim"]
["Chlorpromazine",1,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,1,0,0,0,3,0,1,0,0,0,0,2,0,0,3,0,0,0,0,2,0,13,0,3,1,0,1,"Chlorpromazine"]
["Cyanamide",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,"Cyanamide"]
["cypermethrin",0,0,0,0,0,0,0,0,0,0,0,0,0,0,5,0,0,0,0,1,0,0,0,0,0,0,2,0,1,0,0,0,3,0,1,0,0,0,0,8,1,0,5,0,0,0,1,6,1,11,0,10,0,0,0,"cypermethrin"]
["DEET",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,3,0,2,0,0,0,"DEET"]
["Dibutyl Phthalate",10,1,8,0,0,0,0,0,0,0,0,0,0,0,3,0,0,0,0,17,3,0,0,0,0,1,15,3,3,0,0,0,1,0,5,0,9,0,0,7,1,0,5,0,0,1,0,13,2,20,0,60,0,0,0,"Dibutyl Phthalate"]
["Dichlorodiphenyl Dichloroethylene",4,1,4,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,6,0,0,0,0,0,0,0,0,3,0,0,0,0,0,1,0,0,0,0,9,0,0,8,0,0,0,0,1,0,12,1,5,0,0,0,"Dichlorodiphenyl Dichloroethylene"]
["dicyclohexyl phthalate",0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,1,1,0,0,0,0,0,0,0,0,0,0,2,0,0,0,"dicyclohexyl phthalate"]
["diethyl phthalate",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,"diethyl phthalate"]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & BE37,BE37)","v":"Diethylhexyl Phthalate"},1,0,3,0,0,1,0,0,0,0,1,0,0,0,6,0,0,0,0,16,2,0,0,0,0,0,16,0,3,0,0,0,1,1,6,0,16,0,0,14,0,0,12,0,0,0,5,24,4,35,0,74,0,0,0,"Diethylhexyl Phthalate"]
["Diethylstilbestrol",22,16,12,0,0,1,0,0,5,0,1,2,11,0,22,0,0,0,7,34,0,0,0,0,3,4,14,2,14,5,3,0,10,0,9,0,6,0,1,10,1,0,5,1,0,4,3,30,3,32,21,85,8,3,4,"Diethylstilbestrol"]
["Dimethoate",0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3,0,0,4,0,0,0,0,0,1,7,0,3,0,0,0,"Dimethoate"]
["dimethyl 2,3,5,6-tetrachloroterephthalate",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,"dimethyl 2,3,5,6-tetrachloroterephthalate"]
["Dimethylformamide",0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,4,0,0,0,0,0,0,9,0,1,0,0,0,"Dimethylformamide"]
["di-n-hexyl phthalate",0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,1,0,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0,1,0,0,2,1,0,1,0,0,0,0,0,0,0,0,5,0,0,0,"di-n-hexyl phthalate"]
["di-n-pentyl phthalate",0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,2,0,0,1,0,0,0,0,0,1,1,0,0,2,0,5,0,0,0,"di-n-pentyl phthalate"]
["diphenylguanidine",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,2,0,0,0,"diphenylguanidine"]
["Endosulfan",0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,1,0,0,0,1,0,0,7,1,0,4,1,0,1,4,4,4,10,0,12,0,0,0,"Endosulfan"]
["Estradiol",45,1,12,2,1,1,12,2,19,0,1,1,61,0,22,2,1,3,0,37,4,3,1,8,19,2,34,7,27,8,2,0,27,10,27,4,24,1,1,24,3,3,28,0,1,17,19,161,23,143,7,260,56,3,2,"Estradiol"]
["Ethinyl Estradiol",4,0,2,0,0,0,2,2,5,0,0,0,17,0,9,0,0,0,0,7,2,0,0,25,3,0,5,1,10,1,0,0,8,0,3,0,2,0,0,4,1,0,8,0,0,1,1,16,2,27,1,50,41,3,0,"Ethinyl Estradiol"]
["fenarimol",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,"fenarimol"]
["Fenthion",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,"Fenthion"]
["fluometuron",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,"fluometuron"]
["Flutamide",22,0,5,0,0,1,6,0,2,0,1,0,0,1,13,0,0,0,0,16,0,0,0,31,0,0,8,0,9,3,0,4,7,0,3,0,6,0,0,4,0,0,5,0,0,5,2,20,3,15,0,54,0,0,1,"Flutamide"]
["folpet",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,"folpet"]
["formamide",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,"formamide"]
["Glutaral",1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,2,0,1,0,0,0,"Glutaral"]
["glycidol",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,"glycidol"]
["iprodione",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,"iprodione"]
["irgarol 1051",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3,0,0,0,0,0,"irgarol 1051"]
["Linuron",0,0,0,0,0,0,0,0,0,0,0,0,0,0,3,0,0,0,0,4,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,5,0,0,0,"Linuron"]
["Malathion",0,0,0,0,0,0,0,0,0,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0,1,0,0,0,0,4,0,0,2,0,0,1,3,5,2,10,0,9,0,0,0,"Malathion"]
["Mercuric Chloride",0,0,0,0,0,2,0,0,0,0,0,0,0,0,3,0,0,0,0,2,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,9,0,0,12,0,0,0,0,10,1,15,0,8,0,0,0,"Mercuric Chloride"]
["methamidophos",0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,1,0,0,1,0,0,0,4,0,0,0,0,0,"methamidophos"]
["Methomyl",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,2,0,2,0,0,0,"Methomyl"]
["methyl cellosolve",0,0,0,0,0,0,0,0,0,0,0,0,0,0,9,0,0,0,0,2,0,0,0,0,0,0,1,0,3,0,0,0,3,1,4,0,6,0,0,7,0,0,3,0,0,1,9,11,1,13,0,21,0,0,0,"methyl cellosolve"]
["Methyl Methanesulfonate",0,0,0,0,0,0,0,0,0,0,0,0,0,0,10,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,7,0,2,0,0,5,4,0,1,0,0,6,0,7,0,42,0,11,0,0,1,"Methyl Methanesulfonate"]
["Methyl Parathion",0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,2,0,0,1,0,0,2,1,2,1,5,0,5,0,0,1,"Methyl Parathion"]
["molinate",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,2,0,1,0,0,0,0,0,0,0,0,2,0,2,0,2,0,2,0,0,0,"molinate"]
["N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,"N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide"]
["n-butoxyethanol",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,"n-butoxyethanol"]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & BE69,BE69)","v":"nitrobenzene"},0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,1,0,0,2,0,0,1,0,0,1,3,4,0,3,0,6,0,0,1,"nitrobenzene"]
["Nitrofurazone",0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,3,1,0,2,0,0,0,0,4,0,7,0,5,0,0,3,"Nitrofurazone"]
["paclobutrazol",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,"paclobutrazol"]
["Pentachlorophenol",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,3,0,0,0,"Pentachlorophenol"]
["perfluorobutane",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,"perfluorobutane"]
["perfluorooctanoic acid",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,3,0,0,2,0,0,0,0,0,0,5,1,2,0,0,0,"perfluorooctanoic acid"]
["Phosmet",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,0,0,0,0,2,0,2,0,0,0,"Phosmet"]
["procymidone",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,1,0,2,0,0,0,"procymidone"]
["Propylthiouracil",1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,1,0,2,0,5,0,0,2,0,0,0,0,0,1,1,5,0,5,0,12,1,0,0,"Propylthiouracil"]
["pyrazon",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,"pyrazon"]
["Simazine",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,"Simazine"]
["Sodium Nitrite",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,"Sodium Nitrite"]
["Sulfasalazine",0,0,0,0,0,1,0,0,0,0,0,1,0,0,3,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,12,2,2,17,0,0,0,1,9,0,18,0,5,0,0,0,"Sulfasalazine"]
["systhane",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,"systhane"]
["tebufenozide",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,"tebufenozide"]
["Testosterone Propionate",0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3,0,2,0,0,0,0,0,0,0,0,0,0,3,0,3,0,3,0,0,0,"Testosterone Propionate"]
["thidiazuron",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,"thidiazuron"]
["Thiram",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,0,0,0,0,0,1,3,1,2,0,3,0,0,0,"Thiram"]
["Tretinoin",1,4,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,2,2,0,0,0,0,0,4,4,0,10,0,0,5,0,1,3,0,1,0,6,37,18,15,0,36,0,2,1,"Tretinoin"]
["triadimefon",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,2,0,1,0,0,0,"triadimefon"]
["Trichloroacetic Acid",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,"Trichloroacetic Acid"]
["triphenyltin hydroxide",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,1,0,0,0,1,0,0,0,"triphenyltin hydroxide"]
["vinclozolin",3,0,4,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,8,0,0,0,0,0,0,0,2,5,0,0,0,1,0,3,0,0,0,0,9,0,0,7,0,0,1,0,14,0,15,0,26,0,1,0,"vinclozolin"]
["Ziram",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,"Ziram"]

{"sheet":"Detail","index":2,"n_rows":4387,"n_cols":13,"rows_kept":4387,"cut":false,"hidden":false,"merged":[]}
["Detail"]
["Chemical (hyperlinked)","Disease (hyperlinked)","Tox","Male","PMID","Pub Yr","Title","LinkPMID","LinkChem","LinkEff","281","63","GeneScore"]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3,I3)","v":"((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3,J3)","v":"Epididymis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3,H3)","v":"22431174"},2012,"Effects of clothianidin exposure on sperm quality, testicular apoptosis and fatty acid composition in developing male rats.","22431174","((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Epididymis",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I4,I4)","v":"((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J4,J4)","v":"Epididymis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H4,H4)","v":"23527526"},2013,"Effects of the neonicotinoid insecticide, clothianidin, on the reproductive organ system in adult male rats.","23527526","((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Epididymis",1,1,1]
["((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Genitalia, Male",1,1,"23527526",2013,"Effects of the neonicotinoid insecticide, clothianidin, on the reproductive organ system in adult male rats.","23527526","((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Genitalia, Male",1,1,1]
["((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Seminal Vesicles",1,1,"23527526",2013,"Effects of the neonicotinoid insecticide, clothianidin, on the reproductive organ system in adult male rats.","23527526","((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Seminal Vesicles",1,1,1]
["((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Spermatozoa",1,1,"22431174",2012,"Effects of clothianidin exposure on sperm quality, testicular apoptosis and fatty acid composition in developing male rats.","22431174","((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Spermatozoa",1,1,1]
["((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Spermatozoa",1,1,"23527526",2013,"Effects of the neonicotinoid insecticide, clothianidin, on the reproductive organ system in adult male rats.","23527526","((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Spermatozoa",1,1,1]
["((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Testis",1,1,"22431174",2012,"Effects of clothianidin exposure on sperm quality, testicular apoptosis and fatty acid composition in developing male rats.","22431174","((E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)","Testis",1,1,1]
["1,2,3-trichloropropane","Epididymis",1,1,"9114362",1997,"Reproductive toxicology. 1,2,3-Trichloropropane.","9114362","1,2,3-trichloropropane","Epididymis",1,null,1]
["1,2,3-trichloropropane","Sperm Count",1,1,"9114362",1997,"Reproductive toxicology. 1,2,3-Trichloropropane.","9114362","1,2,3-trichloropropane","Sperm Count",1,null,1]
["1,2,4,5-tetrachlorobenzene","Spermatozoa",1,1,"9114357",1997,"Reproductive toxicology. 1,2,4,5-Tetrachlorobenzene.","9114357","1,2,4,5-tetrachlorobenzene","Spermatozoa",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Epididymis",1,1,"15355714",2004,"[Effect of 2,4-D isooctylester on sperms in tail of epididymis and HSP70 expression of testis tissue in rats].","15355714","2,4-Dichlorophenoxyacetic Acid","Epididymis",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Leydig Cells",1,1,"10330569",1999,"[Effect of 2,4-D ecotoxicants on spermatogenesis and fertility of albino rats].","10330569","2,4-Dichlorophenoxyacetic Acid","Leydig Cells",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Leydig Cells",0,1,"16137705",2006,"Evidence of apoptotic effects of 2,4-D and butachlor on walking catfish, Clarias batrachus, by transmission electron microscopy and DNA degradation studies.","16137705","2,4-Dichlorophenoxyacetic Acid","Leydig Cells",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Prostate",0,1,"21374790",2013,"Oxidative stress in ventral prostate, ovary, and breast by 2,4-dichlorophenoxyacetic acid in pre- and postnatal exposed rats.","21374790","2,4-Dichlorophenoxyacetic Acid","Prostate",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Sertoli Cells",1,1,"10330569",1999,"[Effect of 2,4-D ecotoxicants on spermatogenesis and fertility of albino rats].","10330569","2,4-Dichlorophenoxyacetic Acid","Sertoli Cells",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Sperm Count",1,1,"1986284",1991,"Study of reproductive function in persons occupationally exposed to 2,4-dichlorophenoxyacetic acid (2,4-D).","1986284","2,4-Dichlorophenoxyacetic Acid","Sperm Count",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Sperm Motility",1,1,"1986284",1991,"Study of reproductive function in persons occupationally exposed to 2,4-dichlorophenoxyacetic acid (2,4-D).","1986284","2,4-Dichlorophenoxyacetic Acid","Sperm Motility",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Spermatogenesis",1,1,"10330569",1999,"[Effect of 2,4-D ecotoxicants on spermatogenesis and fertility of albino rats].","10330569","2,4-Dichlorophenoxyacetic Acid","Spermatogenesis",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Spermatogonia",1,1,"11498271",2001,"Induction of sister chromatid exchanges by 2,4-dichlorophenoxyacetic acid in somatic and germ cells of mice exposed in vivo.","11498271","2,4-Dichlorophenoxyacetic Acid","Spermatogonia",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Spermatogonia",0,1,"16137705",2006,"Evidence of apoptotic effects of 2,4-D and butachlor on walking catfish, Clarias batrachus, by transmission electron microscopy and DNA degradation studies.","16137705","2,4-Dichlorophenoxyacetic Acid","Spermatogonia",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,1,"10354001",1999,"Toxicity of metals and pesticides using the sperm cell bioassay with the sea urchin Arbacia spatuligera.","10354001","2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,1,"15355714",2004,"[Effect of 2,4-D isooctylester on sperms in tail of epididymis and HSP70 expression of testis tissue in rats].","15355714","2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,1,"1986284",1991,"Study of reproductive function in persons occupationally exposed to 2,4-dichlorophenoxyacetic acid (2,4-D).","1986284","2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Spermatozoa",0,1,"698414",1978,"Reproductive success of hens and cockerels originating from eggs sprayed with 2,4-D, 2,4-5-T and picloram followed by early performance of their progency after a comparable in ovo exposure.","698414","2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,1,"7338944",1981,"Male fertility, sister chromatid exchange, and germ cell toxicity following exposure to mixtures of chlorinated phenoxy acids containing 2,3,7,8-tetrachlorodibenzo-p-dioxin.","7338944","2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,1,"7338945",1981,"Development and viability of offspring of male mice treated with chlorinated phenoxy acids and 2,3,7,8-tetrachlorodibenzo-p-dioxin.","7338945","2,4-Dichlorophenoxyacetic Acid","Spermatozoa",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Testis",1,1,"23357564",2013,"An evaluation of 2,4-dichlorophenoxyacetic acid in the Amphibian Metamorphosis Assay and the Fish Short-Term Reproduction Assay.","23357564","2,4-Dichlorophenoxyacetic Acid","Testis",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Testis",1,1,"24072463",2013,"An F1-extended one-generation reproductive toxicity study in Crl:CD(SD) rats with 2,4-dichlorophenoxyacetic acid.","24072463","2,4-Dichlorophenoxyacetic Acid","Testis",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Testis",0,1,"698414",1978,"Reproductive success of hens and cockerels originating from eggs sprayed with 2,4-D, 2,4-5-T and picloram followed by early performance of their progency after a comparable in ovo exposure.","698414","2,4-Dichlorophenoxyacetic Acid","Testis",1,null,1]
["2,4-Dichlorophenoxyacetic Acid","Testis",0,1,"964617",1976,"[Study of the effect of the herbicide 2,4-DM on the pregnant body, embryonic development on gonadal function in white rats].","964617","2,4-Dichlorophenoxyacetic Acid","Testis",1,null,1]
["2,4-dinitrotoluene","Sperm Count",1,1,"3135640",1988,"Reproductive toxicity of 2,4-dinitrotoluene in the rat.","3135640","2,4-dinitrotoluene","Sperm Count",1,1,1]
["2,4-dinitrotoluene","Spermatogenesis",1,1,"3135640",1988,"Reproductive toxicity of 2,4-dinitrotoluene in the rat.","3135640","2,4-dinitrotoluene","Spermatogenesis",1,1,1]
["2,4-dinitrotoluene","Spermatogenesis",0,1,"6895726",1980,"Lack of an indication of mutagenic effects of dinitrotoluenes and diaminotoluenes in mice.","6895726","2,4-dinitrotoluene","Spermatogenesis",1,1,1]
["2,4-dinitrotoluene","Spermatozoa",1,1,"6386342",1984,"Dinitrotoluene: acute toxicity, oncogenicity, genotoxicity, and metabolism.","6386342","2,4-dinitrotoluene","Spermatozoa",1,1,1]
["2,4-dinitrotoluene","Testis",1,1,"3135640",1988,"Reproductive toxicity of 2,4-dinitrotoluene in the rat.","3135640","2,4-dinitrotoluene","Testis",1,1,1]
["2-butanone oxime","Spermatogenesis",1,1,"18161510",2008,"Oxime silanes: structure/toxicity relationships.","18161510","2-butanone oxime","Spermatogenesis",1,null,1]
["2-butanone oxime","Testis",1,1,"18161510",2008,"Oxime silanes: structure/toxicity relationships.","18161510","2-butanone oxime","Testis",1,null,1]
["2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide","Spermatozoa",1,1,"11727791",2001,"Factors affecting R6 fungicide toxicity on sea urchin fertilization and early development: roles of exposure routes and mixture components.","11727791","2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide","Spermatozoa",1,null,1]
["2-ethylhexanoic acid","Genitalia, Male",1,1,"8405783",1993,"Effects of 2-ethylhexanoic acid on reproduction and postnatal development in Wistar rats.","8405783","2-ethylhexanoic acid","Genitalia, Male",1,1,1]
["2-ethylhexanoic acid","Sperm Motility",1,1,"8405783",1993,"Effects of 2-ethylhexanoic acid on reproduction and postnatal development in Wistar rats.","8405783","2-ethylhexanoic acid","Sperm Motility",1,1,1]
["2-Methyl-4-chlorophenoxyacetic Acid","Seminiferous Epithelium",0,1,"966232",1976,"Effect of sodium 2-methyl-4-chlorophenoxyacetate on spermatogenesis in the rat.","966232","2-Methyl-4-chlorophenoxyacetic Acid","Seminiferous Epithelium",1,null,1]
["2-Methyl-4-chlorophenoxyacetic Acid","Spermatogenesis",1,1,"17159792",2006,"Adverse effects of herbicide MCPA on dogs in a 90 day toxicological study.","17159792","2-Methyl-4-chlorophenoxyacetic Acid","Spermatogenesis",1,null,1]
["2-Methyl-4-chlorophenoxyacetic Acid","Spermatogenesis",0,1,"966232",1976,"Effect of sodium 2-methyl-4-chlorophenoxyacetate on spermatogenesis in the rat.","966232","2-Methyl-4-chlorophenoxyacetic Acid","Spermatogenesis",1,null,1]
["2-Methyl-4-chlorophenoxyacetic Acid","Testis",1,1,"17159792",2006,"Adverse effects of herbicide MCPA on dogs in a 90 day toxicological study.","17159792","2-Methyl-4-chlorophenoxyacetic Acid","Testis",1,null,1]
["2-Methyl-4-chlorophenoxyacetic Acid","Testis",0,1,"966232",1976,"Effect of sodium 2-methyl-4-chlorophenoxyacetate on spermatogenesis in the rat.","966232","2-Methyl-4-chlorophenoxyacetic Acid","Testis",1,null,1]
["4-nitrobenzoic acid","Epididymis",1,1,"9114347",1997,"Reproductive toxicology. p-Nitrobenzoic acid.","9114347","4-nitrobenzoic acid","Epididymis",1,null,1]
["4-nitrobenzoic acid","Testis",1,1,"9114347",1997,"Reproductive toxicology. p-Nitrobenzoic acid.","9114347","4-nitrobenzoic acid","Testis",1,null,1]
["4-octylphenol","Epididymis",1,1,"16631297",2006,"The toxic effects of 4-tert-octylphenol on the reproductive system of male rats.","16631297","4-octylphenol","Epididymis",1,1,1]
["4-octylphenol","Genitalia, Male",0,1,"9460178",1998,"A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior.","9460178","4-octylphenol","Genitalia, Male",1,1,1]
["4-octylphenol","Leydig Cells",0,1,"8603575",1996,"Expression of cytochrome P450 17alpha-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens.","8603575","4-octylphenol","Leydig Cells",1,1,1]
["4-octylphenol","Prostate",1,1,"16631297",2006,"The toxic effects of 4-tert-octylphenol on the reproductive system of male rats.","16631297","4-octylphenol","Prostate",1,1,1]
["4-octylphenol","Prostate",0,1,"9074884",1997,"Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol.","9074884","4-octylphenol","Prostate",1,1,1]
["4-octylphenol","Sertoli Cells",0,1,"10875272",2000,"Maternal exposure to octylphenol suppresses ovine fetal follicle-stimulating hormone secretion, testis size, and sertoli cell number.","10875272","4-octylphenol","Sertoli Cells",1,1,1]
["4-octylphenol","Sperm Count",1,1,"16631297",2006,"The toxic effects of 4-tert-octylphenol on the reproductive system of male rats.","16631297","4-octylphenol","Sperm Count",1,1,1]
["4-octylphenol","Sperm Count",0,1,"9460178",1998,"A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior.","9460178","4-octylphenol","Sperm Count",1,1,1]
["4-octylphenol","Sperm Motility",1,1,"16631297",2006,"The toxic effects of 4-tert-octylphenol on the reproductive system of male rats.","16631297","4-octylphenol","Sperm Motility",1,1,1]
["4-octylphenol","Spermatogenesis",1,1,"16631297",2006,"The toxic effects of 4-tert-octylphenol on the reproductive system of male rats.","16631297","4-octylphenol","Spermatogenesis",1,1,1]
["4-octylphenol","Spermatogenesis",1,1,"8747020",1995,"Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production.","8747020","4-octylphenol","Spermatogenesis",1,1,1]
["4-octylphenol","Spermatozoa",1,1,"11157813",2001,"Effect of 4-octylphenol on germ cell number in cultured human fetal gonads.","11157813","4-octylphenol","Spermatozoa",1,1,1]
["4-octylphenol","Testis",0,1,"10875272",2000,"Maternal exposure to octylphenol suppresses ovine fetal follicle-stimulating hormone secretion, testis size, and sertoli cell number.","10875272","4-octylphenol","Testis",1,1,1]
["4-octylphenol","Testis",1,1,"11157813",2001,"Effect of 4-octylphenol on germ cell number in cultured human fetal gonads.","11157813","4-octylphenol","Testis",1,1,1]
["4-octylphenol","Testis",1,1,"16631297",2006,"The toxic effects of 4-tert-octylphenol on the reproductive system of male rats.","16631297","4-octylphenol","Testis",1,1,1]
["4-octylphenol","Testis",0,1,"8603575",1996,"Expression of cytochrome P450 17alpha-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens.","8603575","4-octylphenol","Testis",1,1,1]
["4-octylphenol","Testis",1,1,"8747020",1995,"Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production.","8747020","4-octylphenol","Testis",1,1,1]
["4-octylphenol","Testis",0,1,"9099904",1997,"Maternal oestrogen/xenoestrogen exposure alters expression of steroidogenic factor-1 (SF-1/Ad4BP) in the fetal rat testis.","9099904","4-octylphenol","Testis",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I68,I68)","v":"Acetaminophen"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J68,J68)","v":"Adrenal Hyperplasia, Congenital"},1,0,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H68,H68)","v":"24104199"},2014,"MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X chromosome, gene 1 (DAX-1).","24104199","Acetaminophen","Adrenal Hyperplasia, Congenital",1,null,1]
["Acetaminophen","Bladder Exstrophy",1,0,"17184436",2007,"Intravenous paracetamol for postoperative analgesia in a 4-day-old term neonate.","17184436","Acetaminophen","Bladder Exstrophy",1,null,1]
["Acetaminophen","Bladder Exstrophy",0,0,"17897288",2007,"Intravenous paracetamol: the 'Stockholm protocol' for postoperative analgesia of term and preterm neonates.","17897288","Acetaminophen","Bladder Exstrophy",1,null,1]
["Acetaminophen","Cryptorchidism",1,1,"20805751",2010,"Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism.","20805751","Acetaminophen","Cryptorchidism",1,null,1]
["Acetaminophen","Cryptorchidism",0,1,"22612476",2012,"Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.","22612476","Acetaminophen","Cryptorchidism",1,null,1]
["Acetaminophen","Cryptorchidism",1,1,"22852293",2012,"Paracetamol during pregnancy: no particular danger for the child.","22852293","Acetaminophen","Cryptorchidism",1,null,1]
["Acetaminophen","Cryptorchidism",1,1,"24030937",2013,"Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.","24030937","Acetaminophen","Cryptorchidism",1,null,1]
["Acetaminophen","Cryptorchidism",0,1,"7911038",1994,"[Pain control with paracetamol following inguinal herniorrhaphy or orchidopexy in childhood].","7911038","Acetaminophen","Cryptorchidism",1,null,1]
["Acetaminophen","Gonadal Dysgenesis",1,0,"24104199",2014,"MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X chromosome, gene 1 (DAX-1).","24104199","Acetaminophen","Gonadal Dysgenesis",1,null,1]
["Acetaminophen","Hypospadias",0,1,"15283825",2004,"Evaluation of adding preoperative or postoperative rectal paracetamol to caudal bupivacaine for postoperative analgesia in children.","15283825","Acetaminophen","Hypospadias",1,null,1]
["Acetaminophen","Hypospadias",0,1,"19260368",2008,"[Control of postoperative pain in children undergoing hypospadias surgery: quasi-experimental controlled trial].","19260368","Acetaminophen","Hypospadias",1,null,1]
["Acetaminophen","Seminiferous Tubules",1,1,"12499042",2002,"Rat testicular structure and ultrastructure after paracetamol treatment.","12499042","Acetaminophen","Seminiferous Tubules",1,null,1]
["Acetaminophen","Sertoli Cells",1,1,"12499042",2002,"Rat testicular structure and ultrastructure after paracetamol treatment.","12499042","Acetaminophen","Sertoli Cells",1,null,1]
["Acetaminophen","Spermatids",1,1,"12499042",2002,"Rat testicular structure and ultrastructure after paracetamol treatment.","12499042","Acetaminophen","Spermatids",1,null,1]
["Acetaminophen","Spermatocytes",0,1,"7418445",1980,"Cytogenetical action of Paracetamol on meiotic cells of male mice.","7418445","Acetaminophen","Spermatocytes",1,null,1]
["Acetaminophen","Spermatogenesis",0,1,"15935783",2005,"Absence of mouse REC8 cohesin promotes synapsis of sister chromatids in meiosis.","15935783","Acetaminophen","Spermatogenesis",1,null,1]
["Acetaminophen","Spermatogenesis",1,1,"6595979",1984,"Effect of daily high doses of paracetamol given orally during spermatogenesis in the rat testes.","6595979","Acetaminophen","Spermatogenesis",1,null,1]
["Acetaminophen","Spermatogenesis",1,1,"8520128",1995,"Effects of acetaminophen and hydroxyurea on spermatogenesis and sperm chromatin structure in laboratory mice.","8520128","Acetaminophen","Spermatogenesis",1,null,1]
["Acetaminophen","Spermatozoa",1,1,"12499042",2002,"Rat testicular structure and ultrastructure after paracetamol treatment.","12499042","Acetaminophen","Spermatozoa",1,null,1]
["Acetaminophen","Spermatozoa",1,1,"1601223",1992,"Reproductive toxicity evaluation of acetaminophen in Swiss CD-1 mice using a continuous breeding protocol.","1601223","Acetaminophen","Spermatozoa",1,null,1]
["Acetaminophen","Spermatozoa",0,1,"7418445",1980,"Cytogenetical action of Paracetamol on meiotic cells of male mice.","7418445","Acetaminophen","Spermatozoa",1,null,1]
["Acetaminophen","Spermatozoa",1,1,"8520128",1995,"Effects of acetaminophen and hydroxyurea on spermatogenesis and sperm chromatin structure in laboratory mice.","8520128","Acetaminophen","Spermatozoa",1,null,1]
["Acetaminophen","Spermatozoa",1,1,"9114318",1997,"Reproductive toxicology. Acetaminophen.","9114318","Acetaminophen","Spermatozoa",1,null,1]
["Acetaminophen","Testis",1,1,"12499042",2002,"Rat testicular structure and ultrastructure after paracetamol treatment.","12499042","Acetaminophen","Testis",1,null,1]
["Acetaminophen","Testis",0,1,"15935783",2005,"Absence of mouse REC8 cohesin promotes synapsis of sister chromatids in meiosis.","15935783","Acetaminophen","Testis",1,null,1]
["Acetaminophen","Testis",0,1,"22612476",2012,"Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.","22612476","Acetaminophen","Testis",1,null,1]
["Acetaminophen","Testis",1,1,"24030937",2013,"Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.","24030937","Acetaminophen","Testis",1,null,1]
["Acetaminophen","Testis",1,1,"6595979",1984,"Effect of daily high doses of paracetamol given orally during spermatogenesis in the rat testes.","6595979","Acetaminophen","Testis",1,null,1]
["Acetaminophen","Testis",1,1,"8520128",1995,"Effects of acetaminophen and hydroxyurea on spermatogenesis and sperm chromatin structure in laboratory mice.","8520128","Acetaminophen","Testis",1,null,1]
["Acetaminophen","Urogenital Abnormalities",0,0,"16632811",2006,"The analgesic efficacy of acetaminophen, ketoprofen, or their combination for pediatric surgical patients having soft tissue or orthopedic procedures.","16632811","Acetaminophen","Urogenital Abnormalities",1,null,1]
["Acetaminophen","Vas Deferens",1,1,"8520128",1995,"Effects of acetaminophen and hydroxyurea on spermatogenesis and sperm chromatin structure in laboratory mice.","8520128","Acetaminophen","Vas Deferens",1,null,1]
["acetamiprid","Spermatozoa",1,1,"23922925",2013,"Reproductive effects of two neonicotinoid insecticides on mouse sperm function and early embryonic development in vitro.","23922925","acetamiprid","Spermatozoa",1,null,1]
["acetochlor","Sperm Head",1,1,"9393619",1997,"Evaluation of the mutagenicity of acetochlor to male rat germ cells.","9393619","acetochlor","Sperm Head",1,null,1]
["acetochlor","Testis",1,1,"9393619",1997,"Evaluation of the mutagenicity of acetochlor to male rat germ cells.","9393619","acetochlor","Testis",1,null,1]
["Acrylamide","Epididymis",1,1,"18572857",2008,"[Subchronic exposure to acrylamide affects reproduction and testis endocrine function of rats].","18572857","Acrylamide","Epididymis",1,null,1]
["Acrylamide","Epididymis",1,1,"19903525",2010,"Reproductive toxicity of acrylamide-treated male rats.","19903525","Acrylamide","Epididymis",1,null,1]
["Acrylamide","Epididymis",1,1,"20158387",2010,"Enhanced fat consumption potentiates acrylamide-induced oxidative stress in epididymis and epididymal sperm and effect spermatogenesis in mice.","20158387","Acrylamide","Epididymis",1,null,1]
["Acrylamide","Epididymis",1,1,"20554629",2010,"Enhanced role of elaidic acid on acrylamide-induced oxidative stress in epididymis and epididymal sperm that contributed to the impairment of spermatogenesis in mice.","20554629","Acrylamide","Epididymis",1,null,1]
["Acrylamide","Epididymis",1,1,"20705380",2010,"The effects of acrylamide on sperm parameters and membrane integrity of epididymal spermatozoa in mice.","20705380","Acrylamide","Epididymis",1,null,1]
["Acrylamide","Epididymis",1,1,"21415092",2011,"Toxicological effects of acrylamide on the reproductive system of weaning male rats.","21415092","Acrylamide","Epididymis",1,null,1]
["Acrylamide","Epididymis",1,1,"2761561",1989,"Acrylamide binding to the DNA and protamine of spermiogenic stages in the mouse and its relationship to genetic damage.","2761561","Acrylamide","Epididymis",1,null,1]
["Acrylamide","Genitalia, Male",1,1,"18390183",2008,"[Toxicity of acrylamide on male reproduction].","18390183","Acrylamide","Genitalia, Male",1,null,1]
["Acrylamide","Leydig Cells",1,1,"15749267",2005,"Toxicological effects of acrylamide on rat testicular gene expression profile.","15749267","Acrylamide","Leydig Cells",1,null,1]
["Acrylamide","Leydig Cells",1,1,"18572857",2008,"[Subchronic exposure to acrylamide affects reproduction and testis endocrine function of rats].","18572857","Acrylamide","Leydig Cells",1,null,1]
["Acrylamide","Leydig Cells",1,1,"19903525",2010,"Reproductive toxicity of acrylamide-treated male rats.","19903525","Acrylamide","Leydig Cells",1,null,1]
["Acrylamide","Prostate",1,1,"21415092",2011,"Toxicological effects of acrylamide on the reproductive system of weaning male rats.","21415092","Acrylamide","Prostate",1,null,1]
["Acrylamide","Seminiferous Tubules",1,1,"19305978",2009,"Limited lactational transfer of acrylamide to rat offspring on maternal oral administration during the gestation and lactation periods.","19305978","Acrylamide","Seminiferous Tubules",1,null,1]
["Acrylamide","Seminiferous Tubules",1,1,"7520983",1994,"The spermatid micronucleus test with the dissection technique detects the germ cell mutagenicity of acrylamide in rat meiotic cells.","7520983","Acrylamide","Seminiferous Tubules",1,null,1]
["Acrylamide","Sperm Count",1,1,"15749267",2005,"Toxicological effects of acrylamide on rat testicular gene expression profile.","15749267","Acrylamide","Sperm Count",1,null,1]
["Acrylamide","Sperm Count",1,1,"18572857",2008,"[Subchronic exposure to acrylamide affects reproduction and testis endocrine function of rats].","18572857","Acrylamide","Sperm Count",1,null,1]
["Acrylamide","Sperm Count",1,1,"19696015",2010,"Diet-induced obesity in male mice is associated with reduced fertility and potentiation of acrylamide-induced reproductive toxicity.","19696015","Acrylamide","Sperm Count",1,null,1]
["Acrylamide","Sperm Count",1,1,"20158387",2010,"Enhanced fat consumption potentiates acrylamide-induced oxidative stress in epididymis and epididymal sperm and effect spermatogenesis in mice.","20158387","Acrylamide","Sperm Count",1,null,1]
["Acrylamide","Sperm Count",1,1,"9114314",1997,"Reproductive toxicology. Acrylamide.","9114314","Acrylamide","Sperm Count",1,null,1]
["Acrylamide","Sperm Head",1,1,"10820423",2000,"Induction of micronuclei in bone marrow and sperm head abnormalities after combined exposure of mice to low doses of X-rays and acrylamide.","10820423","Acrylamide","Sperm Head",1,null,1]
["Acrylamide","Sperm Head",1,1,"16280212",2006,"Adduction of biomacromolecules with acrylamide (AA) in mice at environmental dose levels studied by accelerator mass spectrometry.","16280212","Acrylamide","Sperm Head",1,null,1]
["Acrylamide","Sperm Head",1,1,"2761561",1989,"Acrylamide binding to the DNA and protamine of spermiogenic stages in the mouse and its relationship to genetic damage.","2761561","Acrylamide","Sperm Head",1,null,1]
["Acrylamide","Sperm Motility",1,1,"10719038",2000,"1-Aminobenzotriazole inhibits acrylamide-induced dominant lethal effects in spermatids of male mice.","10719038","Acrylamide","Sperm Motility",1,null,1]
["Acrylamide","Sperm Motility",1,1,"10825678",2000,"Relationship between acrylamide reproductive and neurotoxicity in male rats.","10825678","Acrylamide","Sperm Motility",1,null,1]
["Acrylamide","Sperm Motility",1,1,"18572857",2008,"[Subchronic exposure to acrylamide affects reproduction and testis endocrine function of rats].","18572857","Acrylamide","Sperm Motility",1,null,1]
["Acrylamide","Sperm Motility",1,1,"19696015",2010,"Diet-induced obesity in male mice is associated with reduced fertility and potentiation of acrylamide-induced reproductive toxicity.","19696015","Acrylamide","Sperm Motility",1,null,1]
["Acrylamide","Sperm Motility",1,1,"20158387",2010,"Enhanced fat consumption potentiates acrylamide-induced oxidative stress in epididymis and epididymal sperm and effect spermatogenesis in mice.","20158387","Acrylamide","Sperm Motility",1,null,1]
["Acrylamide","Sperm Motility",1,1,"20705380",2010,"The effects of acrylamide on sperm parameters and membrane integrity of epididymal spermatozoa in mice.","20705380","Acrylamide","Sperm Motility",1,null,1]
["Acrylamide","Sperm Tail",1,1,"16280212",2006,"Adduction of biomacromolecules with acrylamide (AA) in mice at environmental dose levels studied by accelerator mass spectrometry.","16280212","Acrylamide","Sperm Tail",1,null,1]
["Acrylamide","Spermatids",1,1,"10719038",2000,"1-Aminobenzotriazole inhibits acrylamide-induced dominant lethal effects in spermatids of male mice.","10719038","Acrylamide","Spermatids",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I132,I132)","v":"Acrylamide"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J132,J132)","v":"Spermatids"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H132,H132)","v":"1373224"},1992,"Kinetochore-staining of spermatid micronuclei: studies of mice treated with X-radiation or acrylamide.","1373224","Acrylamide","Spermatids",1,null,1]
["Acrylamide","Spermatids",1,1,"15162050",2004,"Heritable translocations induced by dermal exposure of male mice to acrylamide.","15162050","Acrylamide","Spermatids",1,null,1]
["Acrylamide","Spermatids",1,1,"20026424",2010,"In vitro investigations of glycidamide-induced DNA lesions in mouse male germ cells and in mouse and human lymphocytes.","20026424","Acrylamide","Spermatids",1,null,1]
["Acrylamide","Spermatids",1,1,"7520982",1994,"Increased frequencies of micronuclei in early spermatids of rats following exposure of young primary spermatocytes to acrylamide.","7520982","Acrylamide","Spermatids",1,null,1]
["Acrylamide","Spermatids",1,1,"7520983",1994,"The spermatid micronucleus test with the dissection technique detects the germ cell mutagenicity of acrylamide in rat meiotic cells.","7520983","Acrylamide","Spermatids",1,null,1]
["Acrylamide","Spermatids",1,1,"7520984",1994,"Weak genotoxicity of acrylamide on premeiotic and somatic cells of the mouse.","7520984","Acrylamide","Spermatids",1,null,1]
["Acrylamide","Spermatids",1,1,"7520986",1994,"Dose response for heritable translocations induced by acrylamide in spermatids of mice.","7520986","Acrylamide","Spermatids",1,null,1]
["Acrylamide","Spermatocytes",1,1,"1396605",1992,"Tissue-specific genotoxic effects of acrylamide and acrylonitrile.","1396605","Acrylamide","Spermatocytes",1,null,1]
["Acrylamide","Spermatocytes",1,1,"7520982",1994,"Increased frequencies of micronuclei in early spermatids of rats following exposure of young primary spermatocytes to acrylamide.","7520982","Acrylamide","Spermatocytes",1,null,1]
["Acrylamide","Spermatocytes",1,1,"7520983",1994,"The spermatid micronucleus test with the dissection technique detects the germ cell mutagenicity of acrylamide in rat meiotic cells.","7520983","Acrylamide","Spermatocytes",1,null,1]
["Acrylamide","Spermatocytes",1,1,"7680759",1993,"Perturbation of cell division by acrylamide in vitro and in vivo.","7680759","Acrylamide","Spermatocytes",1,null,1]
["Acrylamide","Spermatocytes",0,1,"8628325",1996,"Induction of hypoploidy and cell cycle delay by acrylamide in somatic and germinal cells of male mice.","8628325","Acrylamide","Spermatocytes",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"10378466",1999,"Acrylamide causes preimplantation abnormalities in embryos and induces chromatin-adducts in male germ cells of mice.","10378466","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"18390183",2008,"[Toxicity of acrylamide on male reproduction].","18390183","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"18930949",2009,"Chromosomal mosaicism in mouse two-cell embryos after paternal exposure to acrylamide.","18930949","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"20036867",2010,"Acrylamide disturbs genomic imprinting during spermatogenesis.","20036867","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"20158387",2010,"Enhanced fat consumption potentiates acrylamide-induced oxidative stress in epididymis and epididymal sperm and effect spermatogenesis in mice.","20158387","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"20554629",2010,"Enhanced role of elaidic acid on acrylamide-induced oxidative stress in epididymis and epididymal sperm that contributed to the impairment of spermatogenesis in mice.","20554629","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"2209570",1990,"Acrylamide exposure induces a delayed unscheduled DNA synthesis in germ cells of male mice that is correlated with the temporal pattern of adduct formation in testis DNA.","2209570","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"22610608",2012,"Chronic exposure to acrylamide induces DNA damage in male germ cells of mice.","22610608","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"2761561",1989,"Acrylamide binding to the DNA and protamine of spermiogenic stages in the mouse and its relationship to genetic damage.","2761561","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"3371457",1988,"Histological changes of acrylamide-induced testicular lesions in mice.","3371457","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"7520985",1994,"Acrylamide-induced chromosomal damage in male mouse germ cells detected by cytogenetic analysis of one-cell zygotes.","7520985","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",0,1,"8628325",1996,"Induction of hypoploidy and cell cycle delay by acrylamide in somatic and germinal cells of male mice.","8628325","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogenesis",1,1,"9435882",1997,"Induction of chromosomal aberrations in mouse zygotes by acrylamide treatment of male germ cells and their correlation with dominant lethality and heritable translocations.","9435882","Acrylamide","Spermatogenesis",1,null,1]
["Acrylamide","Spermatogonia",1,1,"1383787",1992,"Reevaluation of the induction of specific-locus mutations in spermatogonia of the mouse by acrylamide.","1383787","Acrylamide","Spermatogonia",1,null,1]
["Acrylamide","Spermatogonia",1,1,"7520983",1994,"The spermatid micronucleus test with the dissection technique detects the germ cell mutagenicity of acrylamide in rat meiotic cells.","7520983","Acrylamide","Spermatogonia",1,null,1]
["Acrylamide","Spermatogonia",1,1,"7520984",1994,"Weak genotoxicity of acrylamide on premeiotic and somatic cells of the mouse.","7520984","Acrylamide","Spermatogonia",1,null,1]
["Acrylamide","Spermatozoa",0,1,"10229918",1999,"Detection of aneuploidy by multicolor FISH in mouse sperm after in vivo treatment with acrylamide, colchicine, diazepam or thiabendazole.","10229918","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"12507653",2003,"Effects of acrylamide on rodent reproductive performance.","12507653","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"15162050",2004,"Heritable translocations induced by dermal exposure of male mice to acrylamide.","15162050","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"15668104",2005,"Transmitted mutational events induced in mouse germ cells following acrylamide or glycidamide exposure.","15668104","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"15749267",2005,"Toxicological effects of acrylamide on rat testicular gene expression profile.","15749267","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"1601219",1992,"Acrylamide: dermal exposure produces genetic damage in male mouse germ cells.","1601219","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"18572857",2008,"[Subchronic exposure to acrylamide affects reproduction and testis endocrine function of rats].","18572857","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"19903525",2010,"Reproductive toxicity of acrylamide-treated male rats.","19903525","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"2000095",1991,"Induction of specific-locus mutations in male germ cells of the mouse by acrylamide monomer.","2000095","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"20158387",2010,"Enhanced fat consumption potentiates acrylamide-induced oxidative stress in epididymis and epididymal sperm and effect spermatogenesis in mice.","20158387","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"20554629",2010,"Enhanced role of elaidic acid on acrylamide-induced oxidative stress in epididymis and epididymal sperm that contributed to the impairment of spermatogenesis in mice.","20554629","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"20705380",2010,"The effects of acrylamide on sperm parameters and membrane integrity of epididymal spermatozoa in mice.","20705380","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"21196355",2011,"Acrylamide in health and disease.","21196355","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"21415092",2011,"Toxicological effects of acrylamide on the reproductive system of weaning male rats.","21415092","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"2209570",1990,"Acrylamide exposure induces a delayed unscheduled DNA synthesis in germ cells of male mice that is correlated with the temporal pattern of adduct formation in testis DNA.","2209570","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"22610608",2012,"Chronic exposure to acrylamide induces DNA damage in male germ cells of mice.","22610608","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",0,1,"2707253",1989,"The effects of acrylamide on mouse germ-line and somatic cell chromosomes.","2707253","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"3200258",1988,"Clastogenic effects of acrylamide in mouse bone marrow cells.","3200258","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"3325746",1987,"Comparison of the dominant lethal effects of acrylonitrile and acrylamide in male Fischer 344 rats.","3325746","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"3941677",1986,"Dominant lethal effects of acrylamide in male mice.","3941677","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"7623872",1995,"Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk.","7623872","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"9057886",1997,"Somatic and germ cell mutagenesis in lambda lacZ transgenic mice treated with acrylamide or ethylnitrosourea.","9057886","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Spermatozoa",1,1,"9435882",1997,"Induction of chromosomal aberrations in mouse zygotes by acrylamide treatment of male germ cells and their correlation with dominant lethality and heritable translocations.","9435882","Acrylamide","Spermatozoa",1,null,1]
["Acrylamide","Testis",1,1,"15749267",2005,"Toxicological effects of acrylamide on rat testicular gene expression profile.","15749267","Acrylamide","Testis",1,null,1]
["Acrylamide","Testis",1,1,"18303180",2008,"Pathological assessment of the nervous and male reproductive systems of rat offspring exposed maternally to acrylamide during the gestation and lactation periods - a preliminary study.","18303180","Acrylamide","Testis",1,null,1]
["Acrylamide","Testis",1,1,"18572857",2008,"[Subchronic exposure to acrylamide affects reproduction and testis endocrine function of rats].","18572857","Acrylamide","Testis",1,null,1]
["Acrylamide","Testis",1,1,"19696015",2010,"Diet-induced obesity in male mice is associated with reduced fertility and potentiation of acrylamide-induced reproductive toxicity.","19696015","Acrylamide","Testis",1,null,1]
["Acrylamide","Testis",1,1,"19903525",2010,"Reproductive toxicity of acrylamide-treated male rats.","19903525","Acrylamide","Testis",1,null,1]
["Acrylamide","Testis",1,1,"21415092",2011,"Toxicological effects of acrylamide on the reproductive system of weaning male rats.","21415092","Acrylamide","Testis",1,null,1]
["Acrylamide","Testis",1,1,"2209570",1990,"Acrylamide exposure induces a delayed unscheduled DNA synthesis in germ cells of male mice that is correlated with the temporal pattern of adduct formation in testis DNA.","2209570","Acrylamide","Testis",1,null,1]
["Acrylamide","Testis",1,1,"22610608",2012,"Chronic exposure to acrylamide induces DNA damage in male germ cells of mice.","22610608","Acrylamide","Testis",1,null,1]
["Acrylamide","Testis",1,1,"3371457",1988,"Histological changes of acrylamide-induced testicular lesions in mice.","3371457","Acrylamide","Testis",1,null,1]
["Acrylamide","Testis",1,1,"7520982",1994,"Increased frequencies of micronuclei in early spermatids of rats following exposure of young primary spermatocytes to acrylamide.","7520982","Acrylamide","Testis",1,null,1]
["Acrylamide","Testis",1,1,"7520985",1994,"Acrylamide-induced chromosomal damage in male mouse germ cells detected by cytogenetic analysis of one-cell zygotes.","7520985","Acrylamide","Testis",1,null,1]
["Acrylamide","Vas Deferens",1,1,"2761561",1989,"Acrylamide binding to the DNA and protamine of spermiogenic stages in the mouse and its relationship to genetic damage.","2761561","Acrylamide","Vas Deferens",1,null,1]
["alachlor","Sperm Count",1,1,"17049205",2007,"In vitro alachlor effects on reactive oxygen species generation, motility patterns and apoptosis markers in human spermatozoa.","17049205","alachlor","Sperm Count",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I196,I196)","v":"alachlor"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J196,J196)","v":"Sperm Motility"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H196,H196)","v":"17049205"},2007,"In vitro alachlor effects on reactive oxygen species generation, motility patterns and apoptosis markers in human spermatozoa.","17049205","alachlor","Sperm Motility",1,null,1]
["alachlor","Spermatozoa",1,1,"17049205",2007,"In vitro alachlor effects on reactive oxygen species generation, motility patterns and apoptosis markers in human spermatozoa.","17049205","alachlor","Spermatozoa",1,null,1]
["Aldrin","Sperm Count",0,1,"3142959",1988,"Effect of aldrin on spermatogenesis, plasma gonadotrophins and testosterone, and testicular testosterone in the rat.","3142959","Aldrin","Sperm Count",1,null,1]
["Aldrin","Spermatogenesis",0,1,"3142959",1988,"Effect of aldrin on spermatogenesis, plasma gonadotrophins and testosterone, and testicular testosterone in the rat.","3142959","Aldrin","Spermatogenesis",1,null,1]
["Aldrin","Testis",1,1,"1605732",1992,"Evaluation of prenatal aldrin intoxication in rats.","1605732","Aldrin","Testis",1,null,1]
["Aldrin","Testis",0,1,"3142959",1988,"Effect of aldrin on spermatogenesis, plasma gonadotrophins and testosterone, and testicular testosterone in the rat.","3142959","Aldrin","Testis",1,null,1]
["Aspirin","Adrenal Hyperplasia, Congenital",1,1,"11731682",2001,"Index of suspicion.","11731682","Aspirin","Adrenal Hyperplasia, Congenital",1,null,1]
["Aspirin","Adrenogenital Syndrome",0,0,"14157420",1964,"[CLINICAL SIGNIFICANCE OF FEVER-PRODUCING STEROIDS].","14157420","Aspirin","Adrenogenital Syndrome",1,null,1]
["Aspirin","Cryptorchidism",1,1,"20805751",2010,"Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism.","20805751","Aspirin","Cryptorchidism",1,null,1]
["Aspirin","Cryptorchidism",0,1,"22612476",2012,"Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.","22612476","Aspirin","Cryptorchidism",1,null,1]
["Aspirin","Cryptorchidism",1,1,"24030937",2013,"Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.","24030937","Aspirin","Cryptorchidism",1,null,1]
["Aspirin","Epididymis",0,1,"10746868",2000,"Functional activity of mouse sperm was not affected by low doses of aspirin-like drugs.","10746868","Aspirin","Epididymis",1,null,1]
["Aspirin","Epididymis",0,1,"4399",1975,"The effect of prostaglandins and prostaglandin inhibitors on spermatogenesis.","4399","Aspirin","Epididymis",1,null,1]
["Aspirin","Genitalia, Male",1,1,"1771593",1991,"Reversible effects of triamcinolone and lack of effects with aspirin or L-656,224 on external genitalia of male Sprague-Dawley rats exposed in utero.","1771593","Aspirin","Genitalia, Male",1,null,1]
["Aspirin","Genitalia, Male",0,1,"3265382",1988,"Effects of acetylsalicylic acid on reproductive organs of adolescent male rats.","3265382","Aspirin","Genitalia, Male",1,null,1]
["Aspirin","Hypospadias",1,1,"1771593",1991,"Reversible effects of triamcinolone and lack of effects with aspirin or L-656,224 on external genitalia of male Sprague-Dawley rats exposed in utero.","1771593","Aspirin","Hypospadias",1,null,1]
["Aspirin","Leydig Cells",0,1,"646143",1978,"Antispermatogenic effect of aspirin and its prevention by prostaglandin E2.","646143","Aspirin","Leydig Cells",1,null,1]
["Aspirin","Prostate",0,1,"18094213",2008,"Noninvasive quantitation of drug concentration in prostate and seminal vesicles: improvement and validation with desipramine and aspirin.","18094213","Aspirin","Prostate",1,null,1]
["Aspirin","Seminal Vesicles",0,1,"18094213",2008,"Noninvasive quantitation of drug concentration in prostate and seminal vesicles: improvement and validation with desipramine and aspirin.","18094213","Aspirin","Seminal Vesicles",1,null,1]
["Aspirin","Seminal Vesicles",0,1,"4399",1975,"The effect of prostaglandins and prostaglandin inhibitors on spermatogenesis.","4399","Aspirin","Seminal Vesicles",1,null,1]
["Aspirin","Seminiferous Tubules",0,1,"33922",1978,"A quantitative study of the effects of acetylsalicylic acid on spermatogenesis and organs of the rat.","33922","Aspirin","Seminiferous Tubules",1,null,1]
["Aspirin","Sertoli Cells",0,1,"4399",1975,"The effect of prostaglandins and prostaglandin inhibitors on spermatogenesis.","4399","Aspirin","Sertoli Cells",1,null,1]
["Aspirin","Sertoli Cells",0,1,"4461128",1974,"[Prevention of the development of post-traumatic testicular atrophy in rats by administering aspirin].","4461128","Aspirin","Sertoli Cells",1,null,1]
["Aspirin","Sertoli Cells",0,1,"646143",1978,"Antispermatogenic effect of aspirin and its prevention by prostaglandin E2.","646143","Aspirin","Sertoli Cells",1,null,1]
["Aspirin","Sperm Count",0,1,"12586492",2003,"Effects of acetylsalicylic acid and metamizol on hyaluronidase activity and sperm characteristics in rams.","12586492","Aspirin","Sperm Count",1,null,1]
["Aspirin","Sperm Count",0,1,"12690678",2002,"The effect of ethanol on spermatogenesis and fertility in male Sprague-Dawley rats pretreated with acetylsalicylic acid.","12690678","Aspirin","Sperm Count",1,null,1]
["Aspirin","Sperm Count",0,1,"3265382",1988,"Effects of acetylsalicylic acid on reproductive organs of adolescent male rats.","3265382","Aspirin","Sperm Count",1,null,1]
["Aspirin","Sperm Motility",0,1,"12586492",2003,"Effects of acetylsalicylic acid and metamizol on hyaluronidase activity and sperm characteristics in rams.","12586492","Aspirin","Sperm Motility",1,null,1]
["Aspirin","Sperm Motility",0,1,"12690678",2002,"The effect of ethanol on spermatogenesis and fertility in male Sprague-Dawley rats pretreated with acetylsalicylic acid.","12690678","Aspirin","Sperm Motility",1,null,1]
["Aspirin","Sperm Motility",0,1,"3265382",1988,"Effects of acetylsalicylic acid on reproductive organs of adolescent male rats.","3265382","Aspirin","Sperm Motility",1,null,1]
["Aspirin","Spermatids",0,1,"646143",1978,"Antispermatogenic effect of aspirin and its prevention by prostaglandin E2.","646143","Aspirin","Spermatids",1,null,1]
["Aspirin","Spermatids",0,1,"7440017",1980,"Effect of aspirin on spermatogenesis in mature and immature rats.","7440017","Aspirin","Spermatids",1,null,1]
["Aspirin","Spermatocytes",0,1,"33922",1978,"A quantitative study of the effects of acetylsalicylic acid on spermatogenesis and organs of the rat.","33922","Aspirin","Spermatocytes",1,null,1]
["Aspirin","Spermatocytes",0,1,"4399",1975,"The effect of prostaglandins and prostaglandin inhibitors on spermatogenesis.","4399","Aspirin","Spermatocytes",1,null,1]
["Aspirin","Spermatocytes",0,1,"7440017",1980,"Effect of aspirin on spermatogenesis in mature and immature rats.","7440017","Aspirin","Spermatocytes",1,null,1]
["Aspirin","Spermatogenesis",0,1,"12690678",2002,"The effect of ethanol on spermatogenesis and fertility in male Sprague-Dawley rats pretreated with acetylsalicylic acid.","12690678","Aspirin","Spermatogenesis",1,null,1]
["Aspirin","Spermatogenesis",0,1,"33922",1978,"A quantitative study of the effects of acetylsalicylic acid on spermatogenesis and organs of the rat.","33922","Aspirin","Spermatogenesis",1,null,1]
["Aspirin","Spermatogenesis",0,1,"4399",1975,"The effect of prostaglandins and prostaglandin inhibitors on spermatogenesis.","4399","Aspirin","Spermatogenesis",1,null,1]
["Aspirin","Spermatogenesis",0,1,"4461128",1974,"[Prevention of the development of post-traumatic testicular atrophy in rats by administering aspirin].","4461128","Aspirin","Spermatogenesis",1,null,1]
["Aspirin","Spermatogenesis",1,1,"477965",1979,"[Gonadotoxic action of acetylsalicylic acid].","477965","Aspirin","Spermatogenesis",1,null,1]
["Aspirin","Spermatogenesis",0,1,"646143",1978,"Antispermatogenic effect of aspirin and its prevention by prostaglandin E2.","646143","Aspirin","Spermatogenesis",1,null,1]
["Aspirin","Spermatogenesis",0,1,"7440017",1980,"Effect of aspirin on spermatogenesis in mature and immature rats.","7440017","Aspirin","Spermatogenesis",1,null,1]
["Aspirin","Spermatogonia",0,1,"4399",1975,"The effect of prostaglandins and prostaglandin inhibitors on spermatogenesis.","4399","Aspirin","Spermatogonia",1,null,1]
["Aspirin","Spermatozoa",0,1,"10746868",2000,"Functional activity of mouse sperm was not affected by low doses of aspirin-like drugs.","10746868","Aspirin","Spermatozoa",1,null,1]
["Aspirin","Spermatozoa",0,1,"12586492",2003,"Effects of acetylsalicylic acid and metamizol on hyaluronidase activity and sperm characteristics in rams.","12586492","Aspirin","Spermatozoa",1,null,1]
["Aspirin","Spermatozoa",0,1,"12872976",2003,"Effect of acetyl salicylic acid in drinking water on reproductive performance of Japanese quail (Coturnix coturnix japonica).","12872976","Aspirin","Spermatozoa",1,null,1]
["Aspirin","Spermatozoa",0,1,"22974612",2012,"Comparison of the protective effect of dipyridamole and acetylsalicylic acid on long-term histologic damage in a rat model of testicular ischemia-reperfusion injury.","22974612","Aspirin","Spermatozoa",1,null,1]
["Aspirin","Spermatozoa",0,1,"3265382",1988,"Effects of acetylsalicylic acid on reproductive organs of adolescent male rats.","3265382","Aspirin","Spermatozoa",1,null,1]
["Aspirin","Spermatozoa",0,1,"9471925",1997,"[Modulation of peritoneal macrophage function: effect of selected drugs on their activity and sperm phagocytosis].","9471925","Aspirin","Spermatozoa",1,null,1]
["Aspirin","Testis",0,1,"22612476",2012,"Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.","22612476","Aspirin","Testis",1,null,1]
["Aspirin","Testis",0,1,"22974612",2012,"Comparison of the protective effect of dipyridamole and acetylsalicylic acid on long-term histologic damage in a rat model of testicular ischemia-reperfusion injury.","22974612","Aspirin","Testis",1,null,1]
["Aspirin","Testis",1,1,"24030937",2013,"Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.","24030937","Aspirin","Testis",1,null,1]
["Aspirin","Testis",0,1,"3265382",1988,"Effects of acetylsalicylic acid on reproductive organs of adolescent male rats.","3265382","Aspirin","Testis",1,null,1]
["Aspirin","Testis",0,1,"33922",1978,"A quantitative study of the effects of acetylsalicylic acid on spermatogenesis and organs of the rat.","33922","Aspirin","Testis",1,null,1]
["Aspirin","Testis",0,1,"3666819",1987,"In vitro effect of aspirin on NADPH producing pathway in developing human fetus.","3666819","Aspirin","Testis",1,null,1]
["Aspirin","Testis",0,1,"4399",1975,"The effect of prostaglandins and prostaglandin inhibitors on spermatogenesis.","4399","Aspirin","Testis",1,null,1]
["Aspirin","Testis",0,1,"4461128",1974,"[Prevention of the development of post-traumatic testicular atrophy in rats by administering aspirin].","4461128","Aspirin","Testis",1,null,1]
["Aspirin","Testis",1,1,"477965",1979,"[Gonadotoxic action of acetylsalicylic acid].","477965","Aspirin","Testis",1,null,1]
["Aspirin","Testis",0,1,"646143",1978,"Antispermatogenic effect of aspirin and its prevention by prostaglandin E2.","646143","Aspirin","Testis",1,null,1]
["Aspirin","Testis",0,1,"7420204",1980,"Effects of aspirin and related drugs in vitamin E-deficient rats.","7420204","Aspirin","Testis",1,null,1]
["Aspirin","Testis",0,1,"7440017",1980,"Effect of aspirin on spermatogenesis in mature and immature rats.","7440017","Aspirin","Testis",1,null,1]
["Atrazine","Disorders of Sex Development",1,1,"11960004",2002,"Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses.","11960004","Atrazine","Disorders of Sex Development",1,1,1]
["Atrazine","Disorders of Sex Development",1,1,"11961511",2002,"Frogs put in the gender blender by America's favourite herbicide.","11961511","Atrazine","Disorders of Sex Development",1,1,1]
["Atrazine","Disorders of Sex Development",1,1,"11964448",2002,"Amphibian decline. Ubiquitous herbicide emasculates frogs.","11964448","Atrazine","Disorders of Sex Development",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I260,I260)","v":"Atrazine"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J260,J260)","v":"Disorders of Sex Development"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H260,H260)","v":"12410298"},2002,"Herbicides: feminization of male frogs in the wild.","12410298","Atrazine","Disorders of Sex Development",1,1,1]
["Atrazine","Disorders of Sex Development",1,1,"12411672",2002,"Amphibian declines. Conflict brewing over herbicide's link to frog deformities.","12411672","Atrazine","Disorders of Sex Development",1,1,1]
["Atrazine","Disorders of Sex Development",1,1,"12558173",2003,"Response of larval Xenopus laevis to atrazine: assessment of growth, metamorphosis, and gonadal and laryngeal morphology.","12558173","Atrazine","Disorders of Sex Development",1,1,1]
["Atrazine","Disorders of Sex Development",1,1,"12676617",2003,"Atrazine-induced hermaphroditism at 0.1 ppb in American leopard frogs (Rana pipiens): laboratory and field evidence.","12676617","Atrazine","Disorders of Sex Development",1,1,1]
["Atrazine","Disorders of Sex Development",1,1,"16300839",2006,"Atrazine concentrations, gonadal gross morphology and histology in ranid frogs collected in Michigan agricultural areas.","16300839","Atrazine","Disorders of Sex Development",1,1,1]
["Atrazine","Disorders of Sex Development",1,1,"16818259",2006,"Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/feminization hypothesis.","16818259","Atrazine","Disorders of Sex Development",1,1,1]
["Atrazine","Disorders of Sex Development",1,1,"23494929",2013,"Case-control study of maternal residential atrazine exposure and male genital malformations.","23494929","Atrazine","Disorders of Sex Development",1,1,1]
["Atrazine","Epididymis",1,1,"10641017",2000,"Disorders of male rat reproductive tract under the influence of atrazine.","10641017","Atrazine","Epididymis",1,1,1]
["Atrazine","Epididymis",1,1,"19672647",2010,"Changes in sperm characteristics and induction of oxidative stress in the testis and epididymis of experimental rats by a herbicide, atrazine.","19672647","Atrazine","Epididymis",1,1,1]
["Atrazine","Epididymis",1,1,"20083397",2011,"Selenium provides protection to the liver but not the reproductive organs in an atrazine-model of experimental toxicity.","20083397","Atrazine","Epididymis",1,1,1]
["Atrazine","Epididymis",1,1,"20727709",2010,"Effects of prenatal exposure to a low dose atrazine metabolite mixture on pubertal timing and prostate development of male Long-Evans rats.","20727709","Atrazine","Epididymis",1,1,1]
["Atrazine","Foreskin",1,1,"20727709",2010,"Effects of prenatal exposure to a low dose atrazine metabolite mixture on pubertal timing and prostate development of male Long-Evans rats.","20727709","Atrazine","Foreskin",1,1,1]
["Atrazine","Genitalia, Male",1,1,"10641017",2000,"Disorders of male rat reproductive tract under the influence of atrazine.","10641017","Atrazine","Genitalia, Male",1,1,1]
["Atrazine","Genitalia, Male",1,1,"17204298",2007,"Atrazine-induced reproductive tract alterations after transplacental and/or lactational exposure in male Long-Evans rats.","17204298","Atrazine","Genitalia, Male",1,1,1]
["Atrazine","Genitalia, Male",1,1,"17978342",2008,"Gestational exposure to atrazine: effects on the postnatal development of male offspring.","17978342","Atrazine","Genitalia, Male",1,1,1]
["Atrazine","Genitalia, Male",1,1,"20083397",2011,"Selenium provides protection to the liver but not the reproductive organs in an atrazine-model of experimental toxicity.","20083397","Atrazine","Genitalia, Male",1,1,1]
["Atrazine","Genitalia, Male",1,1,"21530639",2011,"Gestational atrazine exposure: effects on male reproductive development and metabolite distribution in the dam, fetus, and neonate.","21530639","Atrazine","Genitalia, Male",1,1,1]
["Atrazine","Genitalia, Male",1,1,"22897171",2013,"Quercetin exacerbates the effects of subacute treatment of atrazine on reproductive tissue antioxidant defence system, lipid peroxidation and sperm quality in rats.","22897171","Atrazine","Genitalia, Male",1,1,1]
["Atrazine","Genitalia, Male",1,1,"7884143",1994,"Effects of atrazine on reproductive performance in the rat.","7884143","Atrazine","Genitalia, Male",1,1,1]
["Atrazine","Gonadal Dysgenesis",1,1,"12410298",2002,"Herbicides: feminization of male frogs in the wild.","12410298","Atrazine","Gonadal Dysgenesis",1,1,1]
["Atrazine","Hypospadias",1,1,"17926863",2007,"[The establishment of hypospadias rat model and embryoteratogenic test of Atrazine].","17926863","Atrazine","Hypospadias",1,1,1]
["Atrazine","Prostate",1,1,"10568700",1999,"Maternal exposure to atrazine during lactation suppresses suckling-induced prolactin release and results in prostatitis in the adult offspring.","10568700","Atrazine","Prostate",1,1,1]
["Atrazine","Prostate",1,1,"20727709",2010,"Effects of prenatal exposure to a low dose atrazine metabolite mixture on pubertal timing and prostate development of male Long-Evans rats.","20727709","Atrazine","Prostate",1,1,1]
["Atrazine","Prostate",1,1,"3695505",1987,"Indirect influence of s-triazines on rat gonadotropic mechanism at early postnatal period.","3695505","Atrazine","Prostate",1,1,1]
["Atrazine","Sertoli Cells",1,1,"23132811",2012,"Dietary antioxidant, quercetin, protects sertoli-germ cell coculture from atrazine-induced oxidative damage.","23132811","Atrazine","Sertoli Cells",1,1,1]
["Atrazine","Sperm Count",1,1,"10641017",2000,"Disorders of male rat reproductive tract under the influence of atrazine.","10641017","Atrazine","Sperm Count",1,1,1]
["Atrazine","Sperm Count",1,1,"24758756",2014,"Toxic effects of atrazine on reproductive system of male rats.","24758756","Atrazine","Sperm Count",1,1,1]
["Atrazine","Sperm Motility",1,1,"10641017",2000,"Disorders of male rat reproductive tract under the influence of atrazine.","10641017","Atrazine","Sperm Motility",1,1,1]
["Atrazine","Spermatids",1,1,"16494226",2006,"Effects of nitrate and atrazine on larval development and sexual differentiation in the northern leopard frog Rana pipiens.","16494226","Atrazine","Spermatids",1,1,1]
["Atrazine","Spermatocytes",1,1,"16494226",2006,"Effects of nitrate and atrazine on larval development and sexual differentiation in the northern leopard frog Rana pipiens.","16494226","Atrazine","Spermatocytes",1,1,1]
["Atrazine","Spermatogenesis",1,1,"10641017",2000,"Disorders of male rat reproductive tract under the influence of atrazine.","10641017","Atrazine","Spermatogenesis",1,1,1]
["Atrazine","Spermatogenesis",0,1,"20045047",2010,"Changes in testicular morphology and steroidogenesis in adult rats exposed to Atrazine.","20045047","Atrazine","Spermatogenesis",1,1,1]
["Atrazine","Spermatogenesis",1,1,"20194757",2010,"Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis).","20194757","Atrazine","Spermatogenesis",1,1,1]
["Atrazine","Spermatozoa",1,1,"11878466",2002,"Response of the amphibian tadpole (Xenopus laevis) to atrazine during sexual differentiation of the testis.","11878466","Atrazine","Spermatozoa",1,1,1]
["Atrazine","Spermatozoa",0,1,"18060860",2008,"Atrazine binds to F1F0-ATP synthase and inhibits mitochondrial function in sperm.","18060860","Atrazine","Spermatozoa",1,1,1]
["Atrazine","Spermatozoa",1,1,"19672647",2010,"Changes in sperm characteristics and induction of oxidative stress in the testis and epididymis of experimental rats by a herbicide, atrazine.","19672647","Atrazine","Spermatozoa",1,1,1]
["Atrazine","Spermatozoa",1,1,"20083397",2011,"Selenium provides protection to the liver but not the reproductive organs in an atrazine-model of experimental toxicity.","20083397","Atrazine","Spermatozoa",1,1,1]
["Atrazine","Spermatozoa",1,1,"20607394",2011,"Pathological and genotoxic effects of atrazine in male Japanese quail (Coturnix japonica).","20607394","Atrazine","Spermatozoa",1,1,1]
["Atrazine","Spermatozoa",1,1,"22897171",2013,"Quercetin exacerbates the effects of subacute treatment of atrazine on reproductive tissue antioxidant defence system, lipid peroxidation and sperm quality in rats.","22897171","Atrazine","Spermatozoa",1,1,1]
["Atrazine","Spermatozoa",1,1,"23132811",2012,"Dietary antioxidant, quercetin, protects sertoli-germ cell coculture from atrazine-induced oxidative damage.","23132811","Atrazine","Spermatozoa",1,1,1]
["Atrazine","Spermatozoa",1,1,"24758756",2014,"Toxic effects of atrazine on reproductive system of male rats.","24758756","Atrazine","Spermatozoa",1,1,1]
["Atrazine","Testis",1,1,"10641017",2000,"Disorders of male rat reproductive tract under the influence of atrazine.","10641017","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"11878466",2002,"Response of the amphibian tadpole (Xenopus laevis) to atrazine during sexual differentiation of the testis.","11878466","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"11964448",2002,"Amphibian decline. Ubiquitous herbicide emasculates frogs.","11964448","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"12410298",2002,"Herbicides: feminization of male frogs in the wild.","12410298","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"12411672",2002,"Amphibian declines. Conflict brewing over herbicide's link to frog deformities.","12411672","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"16418894",2006,"In ovo exposure to a triazine herbicide: effects of atrazine on circulating reproductive hormones and gonadal histology in young Japanese quail.","16418894","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"17978342",2008,"Gestational exposure to atrazine: effects on the postnatal development of male offspring.","17978342","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"18001816",2008,"Reproduction, larval growth, and reproductive development in African clawed frogs (Xenopus laevis) exposed to atrazine.","18001816","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"19672647",2010,"Changes in sperm characteristics and induction of oxidative stress in the testis and epididymis of experimental rats by a herbicide, atrazine.","19672647","Atrazine","Testis",1,1,1]
["Atrazine","Testis",0,1,"20045047",2010,"Changes in testicular morphology and steroidogenesis in adult rats exposed to Atrazine.","20045047","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"20083397",2011,"Selenium provides protection to the liver but not the reproductive organs in an atrazine-model of experimental toxicity.","20083397","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"20194757",2010,"Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis).","20194757","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"20607394",2011,"Pathological and genotoxic effects of atrazine in male Japanese quail (Coturnix japonica).","20607394","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"21530639",2011,"Gestational atrazine exposure: effects on male reproductive development and metabolite distribution in the dam, fetus, and neonate.","21530639","Atrazine","Testis",1,1,1]
["Atrazine","Testis",1,1,"24758756",2014,"Toxic effects of atrazine on reproductive system of male rats.","24758756","Atrazine","Testis",1,1,1]
["bifenthrin","Testis",1,1,"23994515",2013,"Exposure of maternal mice to cis-bifenthrin enantioselectively disrupts the transcription of genes related to testosterone synthesis in male offspring.","23994515","bifenthrin","Testis",1,null,1]
["bisphenol A","Acrosome",1,1,"12148547",2002,"Effect of an endocrine disruptor on mammalian fertility. Application of monoclonal antibodies against sperm proteins as markers for testing sperm damage.","12148547","bisphenol A","Acrosome",1,1,1]
["bisphenol A","Acrosome",0,1,"15700544",2004,"Adverse effects of bisphenol A to spermiogenesis in mice and rats.","15700544","bisphenol A","Acrosome",1,1,1]
["bisphenol A","Blood-Testis Barrier",1,1,"19497385",2009,"Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics?","19497385","bisphenol A","Blood-Testis Barrier",1,1,1]
["bisphenol A","Cryptorchidism",1,1,"23285176",2012,"Individual variation of the genetic response to bisphenol a in human foreskin fibroblast cells derived from cryptorchidism and hypospadias patients.","23285176","bisphenol A","Cryptorchidism",1,1,1]
["bisphenol A","Cryptorchidism",1,1,"23796010",2013,"Bisphenol A: an endocrine and metabolic disruptor.","23796010","bisphenol A","Cryptorchidism",1,1,1]
["bisphenol A","Disorders of Sex Development",1,1,"12631470",2003,"Low dose effects of bisphenol A on sexual differentiation of the brain and behavior in rats.","12631470","bisphenol A","Disorders of Sex Development",1,1,1]
["bisphenol A","Disorders of Sex Development",1,0,"12957472",2003,"Sex reversal effects on Caiman latirostris exposed to environmentally relevant doses of the xenoestrogen bisphenol A.","12957472","bisphenol A","Disorders of Sex Development",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I324,I324)","v":"bisphenol A"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J324,J324)","v":"Disorders of Sex Development"},1,0,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H324,H324)","v":"21333735"},2011,"Epigenetic perspective on the developmental effects of bisphenol A.","21333735","bisphenol A","Disorders of Sex Development",1,1,1]
["bisphenol A","Disorders of Sex Development",1,1,"24271643",2014,"Low dose of bisphenol A impairs the reproductive axis of prepuberal male rats.","24271643","bisphenol A","Disorders of Sex Development",1,1,1]
["bisphenol A","Epididymis",1,1,"10453915",1999,"Reproductive function in rats exposed neonatally to bisphenol A and estradiol benzoate.","10453915","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"10536108",1999,"Normal reproductive organ development in Wistar rats exposed to bisphenol A in the drinking water.","10536108","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"10536110",1999,"Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero.","10536110","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"12505450",2003,"Induction of oxidative stress by bisphenol A in the epididymal sperm of rats.","12505450","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"12804662",2003,"Testicular toxicity of dietarily or parenterally administered bisphenol A in rats and mice.","12804662","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"12937802",2003,"Effect of bisphenol A and co-administration of bisphenol A and vitamin C on epididymis of adult rats: a histological and biochemical study.","12937802","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"15901920",2005,"Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A.","15901920","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"19782717",2009,"Neonatal exposure of male rats to Bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis.","19782717","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"20507349",2010,"Dietary exposure to low doses of bisphenol A: effects on reproduction and development in two generations of C57BL/6J mice.","20507349","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"23788033",2013,"Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity.","23788033","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Epididymis",1,1,"9114321",1997,"Reproductive toxicology. Bisphenol A.","9114321","bisphenol A","Epididymis",1,1,1]
["bisphenol A","Foreskin",0,1,"22574217",2012,"Identification of novel low-dose bisphenol a targets in human foreskin fibroblast cells derived from hypospadias patients.","22574217","bisphenol A","Foreskin",1,1,1]
["bisphenol A","Foreskin",1,1,"23285176",2012,"Individual variation of the genetic response to bisphenol a in human foreskin fibroblast cells derived from cryptorchidism and hypospadias patients.","23285176","bisphenol A","Foreskin",1,1,1]
["bisphenol A","Genitalia, Male",1,1,"10445751",1999,"Normal reproductive organ development in CF-1 mice following prenatal exposure to bisphenol A.","10445751","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Genitalia, Male",1,1,"10536108",1999,"Normal reproductive organ development in Wistar rats exposed to bisphenol A in the drinking water.","10536108","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Genitalia, Male",1,1,"10806412",2000,"Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals.","10806412","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Genitalia, Male",1,1,"11955943",2002,"Low-dose bisphenol A does not affect reproductive organs in estrogen-sensitive C57BL/6N mice exposed at the sexually mature, juvenile, or embryonic stage.","11955943","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Genitalia, Male",1,1,"12062934",2002,"Changes of serum alpha 2u-globulin in the subacute oral toxicity study of ethynyl estradiol and bisphenol A based on the draft protocol for the 'Enhanced OECD Test Guideline No. 407'.","12062934","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Genitalia, Male",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Genitalia, Male",0,1,"18286211",2008,"Effects of estradiol-17beta and bisphenol A administered chronically to mice throughout pregnancy and lactation on the male pups' reproductive system.","18286211","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Genitalia, Male",1,1,"20965246",2011,"Perinatal exposure of rats to Bisphenol A affects fertility of male offspring--an overview.","20965246","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Genitalia, Male",1,1,"21987463",2011,"In utero exposure to bisphenol-A and anogenital distance of male offspring.","21987463","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Genitalia, Male",1,1,"24162092",2014,"Adverse effects of bisphenol A on male reproductive function.","24162092","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Genitalia, Male",0,1,"9460178",1998,"A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior.","9460178","bisphenol A","Genitalia, Male",1,1,1]
["bisphenol A","Hyperandrogenism",0,0,"21193545",2011,"Endocrine disruptors and polycystic ovary syndrome (PCOS): elevated serum levels of bisphenol A in women with PCOS.","21193545","bisphenol A","Hyperandrogenism",1,1,1]
["bisphenol A","Hypospadias",0,1,"22574217",2012,"Identification of novel low-dose bisphenol a targets in human foreskin fibroblast cells derived from hypospadias patients.","22574217","bisphenol A","Hypospadias",1,1,1]
["bisphenol A","Hypospadias",1,1,"23285176",2012,"Individual variation of the genetic response to bisphenol a in human foreskin fibroblast cells derived from cryptorchidism and hypospadias patients.","23285176","bisphenol A","Hypospadias",1,1,1]
["bisphenol A","Leydig Cells",1,1,"12561556",2002,"[Molecular mechanisms of environmental estrogens on reproductive and developmental toxicity].","12561556","bisphenol A","Leydig Cells",1,1,1]
["bisphenol A","Leydig Cells",0,1,"14605012",2004,"Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells.","14605012","bisphenol A","Leydig Cells",1,1,1]
["bisphenol A","Leydig Cells",1,1,"21656274",2011,"Probable gamma-aminobutyric acid involvement in bisphenol A effect at the hypothalamic level in adult male rats.","21656274","bisphenol A","Leydig Cells",1,1,1]
["bisphenol A","Leydig Cells",1,1,"22302688",2012,"The industrial chemical bisphenol A (BPA) interferes with proliferative activity and development of steroidogenic capacity in rat Leydig cells.","22302688","bisphenol A","Leydig Cells",1,1,1]
["bisphenol A","Leydig Cells",0,1,"23284716",2012,"Differential effects of bisphenol A and diethylstilbestrol on human, rat and mouse fetal leydig cell function.","23284716","bisphenol A","Leydig Cells",1,1,1]
["bisphenol A","Leydig Cells",1,1,"24472609",2014,"Bisphenol A regulation of testicular endocrine function in male rats is affected by diet.","24472609","bisphenol A","Leydig Cells",1,1,1]
["bisphenol A","Penis",0,1,"11890520",2001,"Bisphenol A inhibits penile erection via alteration of histology in the rabbit.","11890520","bisphenol A","Penis",1,1,1]
["bisphenol A","Penis",0,1,"16311018",2006,"Effects of bisphenol A given neonatally on reproductive functions of male rats.","16311018","bisphenol A","Penis",1,1,1]
["bisphenol A","Penis",1,1,"24134786",2013,"Chronic high dose intraperitoneal bisphenol A (BPA) induces substantial histological and gene expression alterations in rat penile tissue without impairing erectile function.","24134786","bisphenol A","Penis",1,1,1]
["bisphenol A","Prostate",1,1,"10536110",1999,"Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero.","10536110","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"10806412",2000,"Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals.","10806412","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"10828273",2000,"Pubertal development and reproductive functions of Crl:CD BR Sprague-Dawley rats exposed to bisphenol A during prenatal and postnatal development.","10828273","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"10908839",2000,"Effect of different sampling designs on outcome of endocrine disruptor studies.","10908839","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"11138284",2000,"[Weak sperm--thick prostate. Danger from the baby bottle? (interview by Petra Eiden)].","11138284","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"11357520",2001,"Testicular toxicity of dietary 2,2-bis(4-hydroxyphenyl)propane (bisphenol A) in F344 rats.","11357520","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"11566753",2001,"Prenatal exposure to low doses of bisphenol A alters the periductal stroma and glandular cell function in the rat ventral prostate.","11566753","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"12202049",2002,"Evaluation of the adequacy of published studies of low-dose effects of bisphenol A on the rodent prostate for use in human risk assessment.","12202049","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"12505450",2003,"Induction of oxidative stress by bisphenol A in the epididymal sperm of rats.","12505450","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"12533913",2002,"Lack of significant alteration in the prostate or testis of F344 rat offspring after transplacental and lactational exposure to bisphenol A.","12533913","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",0,1,"12810577",2003,"Bisphenol a induces both transient and permanent histofunctional alterations of the hypothalamic-pituitary-gonadal axis in prenatally exposed male rats.","12810577","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"12974608",2003,"Lack of carcinogenic risk in the prostate with transplacental and lactational exposure to bisphenol A in rats.","12974608","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",0,1,"15751043",2005,"The importance of appropriate controls, animal feed, and animal models in interpreting results from low-dose studies of bisphenol A.","15751043","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"15867144",2005,"Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra.","15867144","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"16740699",2006,"Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4.","16740699","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",0,1,"17459086",2007,"Bisphenol A induces permanent squamous change in mouse prostatic epithelium.","17459086","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"18226066",2008,"Perinatal exposure to oestradiol and bisphenol A alters the prostate epigenome and increases susceptibility to carcinogenesis.","18226066","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"19848444",2010,"Pro-oxidant effect of vitamin C coadministration with bisphenol A, nonylphenol, and octylphenol on the reproductive tract of male rats.","19848444","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"21536718",2011,"Upregulation of clusterin in prostate and DNA damage in spermatozoa from bisphenol A-treated rats and formation of DNA adducts in cultured human prostatic cells.","21536718","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",1,1,"24257414",2014,"Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats.","24257414","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostate",0,1,"9074884",1997,"Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol.","9074884","bisphenol A","Prostate",1,1,1]
["bisphenol A","Prostatic Neoplasms",1,1,"12974608",2003,"Lack of carcinogenic risk in the prostate with transplacental and lactational exposure to bisphenol A in rats.","12974608","bisphenol A","Prostatic Neoplasms",1,1,1]
["bisphenol A","Prostatic Neoplasms",1,1,"16740699",2006,"Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4.","16740699","bisphenol A","Prostatic Neoplasms",1,1,1]
["bisphenol A","Prostatic Neoplasms",1,1,"16757209",2006,"Bisphenol A: do recent studies of health effects among humans inform the long-standing debate?","16757209","bisphenol A","Prostatic Neoplasms",1,1,1]
["bisphenol A","Prostatic Neoplasms",1,1,"18226066",2008,"Perinatal exposure to oestradiol and bisphenol A alters the prostate epigenome and increases susceptibility to carcinogenesis.","18226066","bisphenol A","Prostatic Neoplasms",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I388,I388)","v":"bisphenol A"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J388,J388)","v":"Prostatic Neoplasms"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H388,H388)","v":"21536718"},2011,"Upregulation of clusterin in prostate and DNA damage in spermatozoa from bisphenol A-treated rats and formation of DNA adducts in cultured human prostatic cells.","21536718","bisphenol A","Prostatic Neoplasms",1,1,1]
["bisphenol A","Seminal Vesicles",1,1,"10536110",1999,"Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero.","10536110","bisphenol A","Seminal Vesicles",1,1,1]
["bisphenol A","Seminal Vesicles",1,1,"11357520",2001,"Testicular toxicity of dietary 2,2-bis(4-hydroxyphenyl)propane (bisphenol A) in F344 rats.","11357520","bisphenol A","Seminal Vesicles",1,1,1]
["bisphenol A","Seminal Vesicles",1,1,"12013561",2002,"Effects of bisphenol A on adult male mouse fertility.","12013561","bisphenol A","Seminal Vesicles",1,1,1]
["bisphenol A","Seminal Vesicles",1,1,"12974608",2003,"Lack of carcinogenic risk in the prostate with transplacental and lactational exposure to bisphenol A in rats.","12974608","bisphenol A","Seminal Vesicles",1,1,1]
["bisphenol A","Seminal Vesicles",0,1,"14605012",2004,"Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells.","14605012","bisphenol A","Seminal Vesicles",1,1,1]
["bisphenol A","Seminal Vesicles",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","bisphenol A","Seminal Vesicles",1,1,1]
["bisphenol A","Seminal Vesicles",1,1,"19848444",2010,"Pro-oxidant effect of vitamin C coadministration with bisphenol A, nonylphenol, and octylphenol on the reproductive tract of male rats.","19848444","bisphenol A","Seminal Vesicles",1,1,1]
["bisphenol A","Seminal Vesicles",1,1,"19898982",2010,"Effects of bisphenol A in the ring-legged earwig, Euborellia annulipes.","19898982","bisphenol A","Seminal Vesicles",1,1,1]
["bisphenol A","Seminal Vesicles",1,1,"9114321",1997,"Reproductive toxicology. Bisphenol A.","9114321","bisphenol A","Seminal Vesicles",1,1,1]
["bisphenol A","Seminiferous Epithelium",1,1,"24085620",2014,"Bisphenol A exposure at an environmentally relevant dose induces meiotic abnormalities in adult male rats.","24085620","bisphenol A","Seminiferous Epithelium",1,1,1]
["bisphenol A","Seminiferous Tubules",1,1,"11345455",2001,"Effects of nonylphenol, bisphenol A, and their mixture on the viviparous swordtail fish (Xiphophorus helleri).","11345455","bisphenol A","Seminiferous Tubules",1,1,1]
["bisphenol A","Seminiferous Tubules",1,1,"11357520",2001,"Testicular toxicity of dietary 2,2-bis(4-hydroxyphenyl)propane (bisphenol A) in F344 rats.","11357520","bisphenol A","Seminiferous Tubules",1,1,1]
["bisphenol A","Seminiferous Tubules",1,1,"19379760",2009,"Impairment in protein expression profile of testicular steroid receptor coregulators in male rat offspring perinatally exposed to Bisphenol A.","19379760","bisphenol A","Seminiferous Tubules",1,1,1]
["bisphenol A","Seminiferous Tubules",1,1,"19782717",2009,"Neonatal exposure of male rats to Bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis.","19782717","bisphenol A","Seminiferous Tubules",1,1,1]
["bisphenol A","Seminiferous Tubules",1,1,"19837096",2009,"Perinatal exposure of rats to Bisphenol A affects the fertility of male offspring.","19837096","bisphenol A","Seminiferous Tubules",1,1,1]
["bisphenol A","Seminiferous Tubules",1,1,"23528252",2013,"Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A.","23528252","bisphenol A","Seminiferous Tubules",1,1,1]
["bisphenol A","Sertoli Cells",1,1,"12584010",2003,"Intrauterine bisphenol A exposure leads to stimulatory effects on Sertoli cell number in rats.","12584010","bisphenol A","Sertoli Cells",1,1,1]
["bisphenol A","Sertoli Cells",0,1,"15700544",2004,"Adverse effects of bisphenol A to spermiogenesis in mice and rats.","15700544","bisphenol A","Sertoli Cells",1,1,1]
["bisphenol A","Sertoli Cells",1,1,"19497385",2009,"Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics?","19497385","bisphenol A","Sertoli Cells",1,1,1]
["bisphenol A","Sertoli Cells",1,1,"19782717",2009,"Neonatal exposure of male rats to Bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis.","19782717","bisphenol A","Sertoli Cells",1,1,1]
["bisphenol A","Sertoli Cells",1,1,"21922642",2011,"Effects of in utero exposure to Bisphenol A or diethylstilbestrol on the adult male reproductive system.","21922642","bisphenol A","Sertoli Cells",1,1,1]
["bisphenol A","Sertoli Cells",1,1,"22687993",2012,"Evaluation of the testicular toxicity of prenatal exposure to bisphenol A based on microarray analysis combined with MeSH annotation.","22687993","bisphenol A","Sertoli Cells",1,1,1]
["bisphenol A","Sperm Count",1,1,"11413652",2000,"Reduced sperm counts in guppies (Poecilia reticulata) following exposure to low levels of tributyltin and bisphenol A.","11413652","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"11955943",2002,"Low-dose bisphenol A does not affect reproductive organs in estrogen-sensitive C57BL/6N mice exposed at the sexually mature, juvenile, or embryonic stage.","11955943","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"12013561",2002,"Effects of bisphenol A on adult male mouse fertility.","12013561","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"12505450",2003,"Induction of oxidative stress by bisphenol A in the epididymal sperm of rats.","12505450","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"12533913",2002,"Lack of significant alteration in the prostate or testis of F344 rat offspring after transplacental and lactational exposure to bisphenol A.","12533913","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"12937802",2003,"Effect of bisphenol A and co-administration of bisphenol A and vitamin C on epididymis of adult rats: a histological and biochemical study.","12937802","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",0,1,"16311018",2006,"Effects of bisphenol A given neonatally on reproductive functions of male rats.","16311018","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"19782717",2009,"Neonatal exposure of male rats to Bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis.","19782717","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"19837096",2009,"Perinatal exposure of rats to Bisphenol A affects the fertility of male offspring.","19837096","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"19848444",2010,"Pro-oxidant effect of vitamin C coadministration with bisphenol A, nonylphenol, and octylphenol on the reproductive tract of male rats.","19848444","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"20507349",2010,"Dietary exposure to low doses of bisphenol A: effects on reproduction and development in two generations of C57BL/6J mice.","20507349","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"20656017",2010,"Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinic.","20656017","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"20815788",2010,"Generation of reactive oxygen species in sperms of rats as an earlier marker for evaluating the toxicity of endocrine-disrupting chemicals.","20815788","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"22828881",2011,"Effects of perinatal exposure to bisphenol A and di(2-ethylhexyl)-phthalate on gonadal development of male mice.","22828881","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"23160314",2012,"Estrogen-like disruptive effects of dietary exposure to bisphenol A or 17?-ethinyl estradiol in CD1 mice.","23160314","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"23528252",2013,"Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A.","23528252","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"23770294",2013,"Mutagenic effect of Bisphenol A on adult rat male germ cells and their fertility.","23770294","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",1,1,"9114321",1997,"Reproductive toxicology. Bisphenol A.","9114321","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Count",0,1,"9460178",1998,"A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior.","9460178","bisphenol A","Sperm Count",1,1,1]
["bisphenol A","Sperm Motility",1,1,"12505450",2003,"Induction of oxidative stress by bisphenol A in the epididymal sperm of rats.","12505450","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"12533913",2002,"Lack of significant alteration in the prostate or testis of F344 rat offspring after transplacental and lactational exposure to bisphenol A.","12533913","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"12937802",2003,"Effect of bisphenol A and co-administration of bisphenol A and vitamin C on epididymis of adult rats: a histological and biochemical study.","12937802","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"14557871",2004,"Relief effect of vitamin A on the decreased motility of sperm and the increased incidence of malformed sperm in mice exposed neonatally to bisphenol A.","14557871","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"19782717",2009,"Neonatal exposure of male rats to Bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis.","19782717","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"19837096",2009,"Perinatal exposure of rats to Bisphenol A affects the fertility of male offspring.","19837096","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"20507349",2010,"Dietary exposure to low doses of bisphenol A: effects on reproduction and development in two generations of C57BL/6J mice.","20507349","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"20656017",2010,"Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinic.","20656017","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"20815788",2010,"Generation of reactive oxygen species in sperms of rats as an earlier marker for evaluating the toxicity of endocrine-disrupting chemicals.","20815788","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"22687996",2012,"Lack of effects for dietary exposure of bisphenol A during in utero and lactational periods on reproductive development in rat offspring.","22687996","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"22714401",2012,"Modulations in androgen and estrogen mediating genes and testicular response in male goldfish exposed to bisphenol A.","22714401","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"22730197",2012,"Effect of neonatal exposure on male rats to bisphenol A on the expression of DNA methylation machinery in the postimplantation embryo.","22730197","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"23528252",2013,"Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A.","23528252","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"23596702",2013,"[Effect of vitamin E on reproductive functions and anti-oxidant activity of adolescent male mice exposed to bisphenol A].","23596702","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"23680852",2013,"In vitro effects of bisphenol A on the quality parameters, oxidative stress, DNA integrity and adenosine triphosphate content in sterlet (Acipenser ruthenus) spermatozoa.","23680852","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Sperm Motility",1,1,"23770294",2013,"Mutagenic effect of Bisphenol A on adult rat male germ cells and their fertility.","23770294","bisphenol A","Sperm Motility",1,1,1]
["bisphenol A","Spermatids",1,1,"11357520",2001,"Testicular toxicity of dietary 2,2-bis(4-hydroxyphenyl)propane (bisphenol A) in F344 rats.","11357520","bisphenol A","Spermatids",1,1,1]
["bisphenol A","Spermatids",0,1,"15700544",2004,"Adverse effects of bisphenol A to spermiogenesis in mice and rats.","15700544","bisphenol A","Spermatids",1,1,1]
["bisphenol A","Spermatocytes",1,1,"23788033",2013,"Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity.","23788033","bisphenol A","Spermatocytes",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"10536108",1999,"Normal reproductive organ development in Wistar rats exposed to bisphenol A in the drinking water.","10536108","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"10536110",1999,"Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero.","10536110","bisphenol A","Spermatogenesis",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I452,I452)","v":"bisphenol A"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J452,J452)","v":"Spermatogenesis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H452,H452)","v":"11413652"},2000,"Reduced sperm counts in guppies (Poecilia reticulata) following exposure to low levels of tributyltin and bisphenol A.","11413652","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"12148547",2002,"Effect of an endocrine disruptor on mammalian fertility. Application of monoclonal antibodies against sperm proteins as markers for testing sperm damage.","12148547","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",0,1,"12528833",2003,"Effects of bisphenol-A on the growth of comb and testes of male chicken.","12528833","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",0,1,"12773777",2003,"The effect on sperm production in adult Sprague-Dawley rats exposed by gavage to bisphenol A between postnatal days 91-97.","12773777","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"15501383",2004,"Effects of neonatal administration of 17beta-estradiol, beta-estradiol 3-benzoate, or bisphenol A on mouse and rat spermatogenesis.","15501383","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",0,1,"15700544",2004,"Adverse effects of bisphenol A to spermiogenesis in mice and rats.","15700544","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"16140606",2005,"Comparison of study controls.","16140606","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"16297413",2006,"Inhibition of male chick phenotypes and spermatogenesis by Bisphenol-A.","16297413","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",0,1,"18286211",2008,"Effects of estradiol-17beta and bisphenol A administered chronically to mice throughout pregnancy and lactation on the male pups' reproductive system.","18286211","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"19379760",2009,"Impairment in protein expression profile of testicular steroid receptor coregulators in male rat offspring perinatally exposed to Bisphenol A.","19379760","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"19497385",2009,"Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics?","19497385","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"20965246",2011,"Perinatal exposure of rats to Bisphenol A affects fertility of male offspring--an overview.","20965246","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"21922642",2011,"Effects of in utero exposure to Bisphenol A or diethylstilbestrol on the adult male reproductive system.","21922642","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"22688978",2012,"Contribution of environmental pollutants to male infertily: a working model of germ cell apoptosis induced by plasticizers.","22688978","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"22951085",2013,"Exposure to bisphenol A results in a decline in mouse spermatogenesis.","22951085","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"23528252",2013,"Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A.","23528252","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"23770294",2013,"Mutagenic effect of Bisphenol A on adult rat male germ cells and their fertility.","23770294","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"23788033",2013,"Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity.","23788033","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"24085620",2014,"Bisphenol A exposure at an environmentally relevant dose induces meiotic abnormalities in adult male rats.","24085620","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogenesis",1,1,"24162092",2014,"Adverse effects of bisphenol A on male reproductive function.","24162092","bisphenol A","Spermatogenesis",1,1,1]
["bisphenol A","Spermatogonia",1,1,"21813366",2011,"Low concentrations of bisphenol A induce mouse spermatogonial cell proliferation by G protein-coupled receptor 30 and estrogen receptor-?.","21813366","bisphenol A","Spermatogonia",1,1,1]
["bisphenol A","Spermatogonia",0,1,"23274518",2013,"Bisphenol A at a low concentration boosts mouse spermatogonial cell proliferation by inducing the G protein-coupled receptor 30 expression.","23274518","bisphenol A","Spermatogonia",1,1,1]
["bisphenol A","Spermatozoa",1,1,"10536108",1999,"Normal reproductive organ development in Wistar rats exposed to bisphenol A in the drinking water.","10536108","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"11138284",2000,"[Weak sperm--thick prostate. Danger from the baby bottle? (interview by Petra Eiden)].","11138284","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"12062934",2002,"Changes of serum alpha 2u-globulin in the subacute oral toxicity study of ethynyl estradiol and bisphenol A based on the draft protocol for the 'Enhanced OECD Test Guideline No. 407'.","12062934","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"12148547",2002,"Effect of an endocrine disruptor on mammalian fertility. Application of monoclonal antibodies against sperm proteins as markers for testing sperm damage.","12148547","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"12151630",2002,"Normal sexual development of two strains of rat exposed in utero to low doses of bisphenol A.","12151630","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"12505450",2003,"Induction of oxidative stress by bisphenol A in the epididymal sperm of rats.","12505450","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",0,1,"12528833",2003,"Effects of bisphenol-A on the growth of comb and testes of male chicken.","12528833","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"12782508",2003,"Adverse health effects of bisphenol A in early life.","12782508","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"12804662",2003,"Testicular toxicity of dietarily or parenterally administered bisphenol A in rats and mice.","12804662","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"12937802",2003,"Effect of bisphenol A and co-administration of bisphenol A and vitamin C on epididymis of adult rats: a histological and biochemical study.","12937802","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"14557871",2004,"Relief effect of vitamin A on the decreased motility of sperm and the increased incidence of malformed sperm in mice exposed neonatally to bisphenol A.","14557871","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"15501383",2004,"Effects of neonatal administration of 17beta-estradiol, beta-estradiol 3-benzoate, or bisphenol A on mouse and rat spermatogenesis.","15501383","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"16093527",2005,"Induction of reactive oxygen species by bisphenol A and abrogation of bisphenol A-induced cell injury by DJ-1.","16093527","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"18214894",2008,"Effects of bisphenol A on the embryonic development of sea urchin (Paracentrotus lividus).","18214894","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"19848444",2010,"Pro-oxidant effect of vitamin C coadministration with bisphenol A, nonylphenol, and octylphenol on the reproductive tract of male rats.","19848444","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"20656017",2010,"Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinic.","20656017","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"20813173",2010,"Mitochondrial signaling pathway is also involved in bisphenol A induced germ cell apoptosis in testes.","20813173","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"20815788",2010,"Generation of reactive oxygen species in sperms of rats as an earlier marker for evaluating the toxicity of endocrine-disrupting chemicals.","20815788","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"21536718",2011,"Upregulation of clusterin in prostate and DNA damage in spermatozoa from bisphenol A-treated rats and formation of DNA adducts in cultured human prostatic cells.","21536718","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"22687993",2012,"Evaluation of the testicular toxicity of prenatal exposure to bisphenol A based on microarray analysis combined with MeSH annotation.","22687993","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"22714401",2012,"Modulations in androgen and estrogen mediating genes and testicular response in male goldfish exposed to bisphenol A.","22714401","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"22951085",2013,"Exposure to bisphenol A results in a decline in mouse spermatogenesis.","22951085","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"23160314",2012,"Estrogen-like disruptive effects of dietary exposure to bisphenol A or 17?-ethinyl estradiol in CD1 mice.","23160314","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"23402883",2013,"Melatonin ameliorates bisphenol A-induced DNA damage in the germ cells of adult male rats.","23402883","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"23451610",2013,"[Bisphenol A: a certain or verified toxin?].","23451610","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"23653003",2013,"Aberrant DNA methylation at Igf2-H19 imprinting control region in spermatozoa upon neonatal exposure to bisphenol A and its association with post implantation loss.","23653003","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"23680852",2013,"In vitro effects of bisphenol A on the quality parameters, oxidative stress, DNA integrity and adenosine triphosphate content in sterlet (Acipenser ruthenus) spermatozoa.","23680852","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"23770294",2013,"Mutagenic effect of Bisphenol A on adult rat male germ cells and their fertility.","23770294","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"24293158",2014,"LINE-1 hypomethylation in spermatozoa is associated with Bisphenol A exposure.","24293158","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Spermatozoa",1,1,"24793715",2014,"F0 maternal BPA exposure induced glucose intolerance of F2 generation through DNA methylation change in Gck.","24793715","bisphenol A","Spermatozoa",1,1,1]
["bisphenol A","Testis",1,1,"10453915",1999,"Reproductive function in rats exposed neonatally to bisphenol A and estradiol benzoate.","10453915","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"10536110",1999,"Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero.","10536110","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"10828273",2000,"Pubertal development and reproductive functions of Crl:CD BR Sprague-Dawley rats exposed to bisphenol A during prenatal and postnatal development.","10828273","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"11345455",2001,"Effects of nonylphenol, bisphenol A, and their mixture on the viviparous swordtail fish (Xiphophorus helleri).","11345455","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"11357520",2001,"Testicular toxicity of dietary 2,2-bis(4-hydroxyphenyl)propane (bisphenol A) in F344 rats.","11357520","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"12013561",2002,"Effects of bisphenol A on adult male mouse fertility.","12013561","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"12505450",2003,"Induction of oxidative stress by bisphenol A in the epididymal sperm of rats.","12505450","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",0,1,"12528833",2003,"Effects of bisphenol-A on the growth of comb and testes of male chicken.","12528833","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"12533913",2002,"Lack of significant alteration in the prostate or testis of F344 rat offspring after transplacental and lactational exposure to bisphenol A.","12533913","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"12573901",2003,"Aggressive behavior and serum testosterone concentration during the maturation process of male mice: the effects of fetal exposure to bisphenol A.","12573901","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"12584010",2003,"Intrauterine bisphenol A exposure leads to stimulatory effects on Sertoli cell number in rats.","12584010","bisphenol A","Testis",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I516,I516)","v":"bisphenol A"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J516,J516)","v":"Testis"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H516,H516)","v":"12773777"},2003,"The effect on sperm production in adult Sprague-Dawley rats exposed by gavage to bisphenol A between postnatal days 91-97.","12773777","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"14557871",2004,"Relief effect of vitamin A on the decreased motility of sperm and the increased incidence of malformed sperm in mice exposed neonatally to bisphenol A.","14557871","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",0,1,"14605012",2004,"Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells.","14605012","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"14620671",2003,"Imbalance of testosterone level in male offspring of rats perinatally exposed to bisphenol A.","14620671","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"15051418",2004,"Exposure to bisphenol A during embryonic/fetal life and infancy increases oxidative injury and causes underdevelopment of the brain and testis in mice.","15051418","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"15501383",2004,"Effects of neonatal administration of 17beta-estradiol, beta-estradiol 3-benzoate, or bisphenol A on mouse and rat spermatogenesis.","15501383","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",0,1,"15700544",2004,"Adverse effects of bisphenol A to spermiogenesis in mice and rats.","15700544","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"15738621",2005,"Effects of in utero exposure to bisphenol A on mRNA expression of arylhydrocarbon and retinoid receptors in murine embryos.","15738621","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"15886896",2005,"Toxic effects of bisphenol A on sexual and asexual reproduction in Hydra oligactis.","15886896","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"15901920",2005,"Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A.","15901920","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"16297413",2006,"Inhibition of male chick phenotypes and spermatogenesis by Bisphenol-A.","16297413","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",0,1,"16311018",2006,"Effects of bisphenol A given neonatally on reproductive functions of male rats.","16311018","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"18445619",2008,"Two-generation reproductive toxicity study of dietary bisphenol A in CD-1 (Swiss) mice.","18445619","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"19379760",2009,"Impairment in protein expression profile of testicular steroid receptor coregulators in male rat offspring perinatally exposed to Bisphenol A.","19379760","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"19782717",2009,"Neonatal exposure of male rats to Bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis.","19782717","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"19837096",2009,"Perinatal exposure of rats to Bisphenol A affects the fertility of male offspring.","19837096","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"19848444",2010,"Pro-oxidant effect of vitamin C coadministration with bisphenol A, nonylphenol, and octylphenol on the reproductive tract of male rats.","19848444","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"19898982",2010,"Effects of bisphenol A in the ring-legged earwig, Euborellia annulipes.","19898982","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"20813173",2010,"Mitochondrial signaling pathway is also involved in bisphenol A induced germ cell apoptosis in testes.","20813173","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"21182934",2011,"Effect of perinatal and postnatal bisphenol A exposure to the regulatory circuits at the hypothalamus-pituitary-gonadal axis of CD-1 mice.","21182934","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"21656274",2011,"Probable gamma-aminobutyric acid involvement in bisphenol A effect at the hypothalamic level in adult male rats.","21656274","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",0,1,"21827818",2011,"Hypermethylation of estrogen receptor promoter region in adult testis of rats exposed neonatally to bisphenol A.","21827818","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"21922642",2011,"Effects of in utero exposure to Bisphenol A or diethylstilbestrol on the adult male reproductive system.","21922642","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"22036266",2012,"Adverse effects of bisphenol A on reproductive physiology in male goldfish at environmentally relevant concentrations.","22036266","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"22687993",2012,"Evaluation of the testicular toxicity of prenatal exposure to bisphenol A based on microarray analysis combined with MeSH annotation.","22687993","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"22688978",2012,"Contribution of environmental pollutants to male infertily: a working model of germ cell apoptosis induced by plasticizers.","22688978","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"22714401",2012,"Modulations in androgen and estrogen mediating genes and testicular response in male goldfish exposed to bisphenol A.","22714401","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"22752971",2012,"Effects of transplacental 17-?-ethynyl estradiol or bisphenol A on the developmental profile of steroidogenic acute regulatory protein in the rat testis.","22752971","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"22828881",2011,"Effects of perinatal exposure to bisphenol A and di(2-ethylhexyl)-phthalate on gonadal development of male mice.","22828881","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"22951085",2013,"Exposure to bisphenol A results in a decline in mouse spermatogenesis.","22951085","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",0,1,"23284716",2012,"Differential effects of bisphenol A and diethylstilbestrol on human, rat and mouse fetal leydig cell function.","23284716","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"23528252",2013,"Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A.","23528252","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"23596702",2013,"[Effect of vitamin E on reproductive functions and anti-oxidant activity of adolescent male mice exposed to bisphenol A].","23596702","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"24162092",2014,"Adverse effects of bisphenol A on male reproductive function.","24162092","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"24271643",2014,"Low dose of bisphenol A impairs the reproductive axis of prepuberal male rats.","24271643","bisphenol A","Testis",1,1,1]
["bisphenol A","Testis",1,1,"24472609",2014,"Bisphenol A regulation of testicular endocrine function in male rats is affected by diet.","24472609","bisphenol A","Testis",1,1,1]
["bisphenol A","Urethra",1,1,"15867144",2005,"Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra.","15867144","bisphenol A","Urethra",1,1,1]
["boric acid","Epididymis",1,1,"10478334",1999,"Availability of sperm examination for male reproductive toxicities in rats treated with boric acid.","10478334","boric acid","Epididymis",1,null,1]
["boric acid","Epididymis",1,1,"11349447",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 23). A comparative 2- and 4-week repeated oral dose testicular toxicity study of boric acid in rats.","11349447","boric acid","Epididymis",1,null,1]
["boric acid","Epididymis",1,1,"11349449",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 24). Testicular toxicity of boric acid after 2- and 4-week administration periods.","11349449","boric acid","Epididymis",1,null,1]
["boric acid","Epididymis",1,1,"1765217",1991,"Reproductive toxicity of boric acid in Swiss (CD-1) mice: assessment using the continuous breeding protocol.","1765217","boric acid","Epididymis",1,null,1]
["boric acid","Epididymis",1,1,"9114322",1997,"Reproductive toxicology. Boric acid.","9114322","boric acid","Epididymis",1,null,1]
["boric acid","Prostate",1,1,"10478334",1999,"Availability of sperm examination for male reproductive toxicities in rats treated with boric acid.","10478334","boric acid","Prostate",1,null,1]
["boric acid","Prostate",1,1,"11349447",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 23). A comparative 2- and 4-week repeated oral dose testicular toxicity study of boric acid in rats.","11349447","boric acid","Prostate",1,null,1]
["boric acid","Prostate",1,1,"2213925",1990,"Effect of acute exposure to boric acid on the male reproductive system of the rat.","2213925","boric acid","Prostate",1,null,1]
["boric acid","Seminal Vesicles",1,1,"10478334",1999,"Availability of sperm examination for male reproductive toxicities in rats treated with boric acid.","10478334","boric acid","Seminal Vesicles",1,null,1]
["boric acid","Seminal Vesicles",1,1,"11349447",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 23). A comparative 2- and 4-week repeated oral dose testicular toxicity study of boric acid in rats.","11349447","boric acid","Seminal Vesicles",1,null,1]
["boric acid","Seminal Vesicles",1,1,"2213925",1990,"Effect of acute exposure to boric acid on the male reproductive system of the rat.","2213925","boric acid","Seminal Vesicles",1,null,1]
["boric acid","Seminiferous Epithelium",1,1,"11349447",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 23). A comparative 2- and 4-week repeated oral dose testicular toxicity study of boric acid in rats.","11349447","boric acid","Seminiferous Epithelium",1,null,1]
["boric acid","Seminiferous Epithelium",1,1,"11349449",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 24). Testicular toxicity of boric acid after 2- and 4-week administration periods.","11349449","boric acid","Seminiferous Epithelium",1,null,1]
["boric acid","Seminiferous Tubules",1,1,"1765217",1991,"Reproductive toxicity of boric acid in Swiss (CD-1) mice: assessment using the continuous breeding protocol.","1765217","boric acid","Seminiferous Tubules",1,null,1]
["boric acid","Sperm Count",1,1,"10478334",1999,"Availability of sperm examination for male reproductive toxicities in rats treated with boric acid.","10478334","boric acid","Sperm Count",1,null,1]
["boric acid","Sperm Count",1,1,"11349447",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 23). A comparative 2- and 4-week repeated oral dose testicular toxicity study of boric acid in rats.","11349447","boric acid","Sperm Count",1,null,1]
["boric acid","Sperm Count",1,1,"2213925",1990,"Effect of acute exposure to boric acid on the male reproductive system of the rat.","2213925","boric acid","Sperm Count",1,null,1]
["boric acid","Sperm Count",1,1,"9114322",1997,"Reproductive toxicology. Boric acid.","9114322","boric acid","Sperm Count",1,null,1]
["boric acid","Sperm Motility",1,1,"10478334",1999,"Availability of sperm examination for male reproductive toxicities in rats treated with boric acid.","10478334","boric acid","Sperm Motility",1,null,1]
["boric acid","Sperm Motility",1,1,"11349447",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 23). A comparative 2- and 4-week repeated oral dose testicular toxicity study of boric acid in rats.","11349447","boric acid","Sperm Motility",1,null,1]
["boric acid","Sperm Motility",1,1,"19962437",2010,"Chronic boron exposure and human semen parameters.","19962437","boric acid","Sperm Motility",1,null,1]
["boric acid","Spermatogenesis",1,1,"11349447",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 23). A comparative 2- and 4-week repeated oral dose testicular toxicity study of boric acid in rats.","11349447","boric acid","Spermatogenesis",1,null,1]
["boric acid","Spermatogenesis",1,1,"11349449",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 24). Testicular toxicity of boric acid after 2- and 4-week administration periods.","11349449","boric acid","Spermatogenesis",1,null,1]
["boric acid","Spermatogenesis",1,1,"1765217",1991,"Reproductive toxicity of boric acid in Swiss (CD-1) mice: assessment using the continuous breeding protocol.","1765217","boric acid","Spermatogenesis",1,null,1]
["boric acid","Spermatogenesis",1,1,"2744563",1989,"[Polynuclear genital cells in rat spermatogenesis in the normal state and after exposure to xenobiotics].","2744563","boric acid","Spermatogenesis",1,null,1]
["boric acid","Spermatogenesis",1,1,"7889870",1994,"Chemical disposition of boron in animals and humans.","7889870","boric acid","Spermatogenesis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I580,I580)","v":"boric acid"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J580,J580)","v":"Spermatogenesis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H580,H580)","v":"7889889"},1994,"Toxicity and carcinogenicity studies of boric acid in male and female B6C3F1 mice.","7889889","boric acid","Spermatogenesis",1,null,1]
["boric acid","Spermatogenesis",1,1,"7889890",1994,"Mechanism of the testicular toxicity of boric acid in rats: in vivo and in vitro studies.","7889890","boric acid","Spermatogenesis",1,null,1]
["boric acid","Spermatozoa",1,1,"10478334",1999,"Availability of sperm examination for male reproductive toxicities in rats treated with boric acid.","10478334","boric acid","Spermatozoa",1,null,1]
["boric acid","Spermatozoa",1,1,"19962437",2010,"Chronic boron exposure and human semen parameters.","19962437","boric acid","Spermatozoa",1,null,1]
["boric acid","Spermatozoa",1,1,"21424392",2011,"Reproductive toxicity parameters and biological monitoring in occupationally and environmentally boron-exposed persons in Bandirma, Turkey.","21424392","boric acid","Spermatozoa",1,null,1]
["boric acid","Spermatozoa",1,1,"2213925",1990,"Effect of acute exposure to boric acid on the male reproductive system of the rat.","2213925","boric acid","Spermatozoa",1,null,1]
["boric acid","Spermatozoa",1,1,"2744563",1989,"[Polynuclear genital cells in rat spermatogenesis in the normal state and after exposure to xenobiotics].","2744563","boric acid","Spermatozoa",1,null,1]
["boric acid","Testis",1,1,"11349447",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 23). A comparative 2- and 4-week repeated oral dose testicular toxicity study of boric acid in rats.","11349447","boric acid","Testis",1,null,1]
["boric acid","Testis",1,1,"11349449",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 24). Testicular toxicity of boric acid after 2- and 4-week administration periods.","11349449","boric acid","Testis",1,null,1]
["boric acid","Testis",1,1,"1765217",1991,"Reproductive toxicity of boric acid in Swiss (CD-1) mice: assessment using the continuous breeding protocol.","1765217","boric acid","Testis",1,null,1]
["boric acid","Testis",1,1,"2213925",1990,"Effect of acute exposure to boric acid on the male reproductive system of the rat.","2213925","boric acid","Testis",1,null,1]
["boric acid","Testis",1,1,"23301826",2013,"Impact of boric acid exposure at different concentrations on testicular DNA and male rats fertility.","23301826","boric acid","Testis",1,null,1]
["boric acid","Testis",1,1,"2744563",1989,"[Polynuclear genital cells in rat spermatogenesis in the normal state and after exposure to xenobiotics].","2744563","boric acid","Testis",1,null,1]
["boric acid","Testis",1,1,"7889870",1994,"Chemical disposition of boron in animals and humans.","7889870","boric acid","Testis",1,null,1]
["boric acid","Testis",1,1,"7889889",1994,"Toxicity and carcinogenicity studies of boric acid in male and female B6C3F1 mice.","7889889","boric acid","Testis",1,null,1]
["boric acid","Testis",1,1,"7889890",1994,"Mechanism of the testicular toxicity of boric acid in rats: in vivo and in vitro studies.","7889890","boric acid","Testis",1,null,1]
["boric acid","Testis",1,1,"9114322",1997,"Reproductive toxicology. Boric acid.","9114322","boric acid","Testis",1,null,1]
["butachlor","Leydig Cells",0,1,"16137705",2006,"Evidence of apoptotic effects of 2,4-D and butachlor on walking catfish, Clarias batrachus, by transmission electron microscopy and DNA degradation studies.","16137705","butachlor","Leydig Cells",1,null,1]
["butachlor","Spermatogonia",0,1,"16137705",2006,"Evidence of apoptotic effects of 2,4-D and butachlor on walking catfish, Clarias batrachus, by transmission electron microscopy and DNA degradation studies.","16137705","butachlor","Spermatogonia",1,null,1]
["carbendazim","Acrosome",1,1,"9281846",1997,"Further observations on carbendazim-induced abnormalities of spermatid morphology in rats.","9281846","carbendazim","Acrosome",1,1,1]
["carbendazim","Acrosome",1,1,"9724464",1998,"Carbendazim-induced abnormal development of the acrosome during early phases of spermiogenesis in the rat testis.","9724464","carbendazim","Acrosome",1,1,1]
["carbendazim","Epididymis",1,1,"11831377",2001,"Spermatotoxic effect of carbendazim.","11831377","carbendazim","Epididymis",1,1,1]
["carbendazim","Seminiferous Tubules",1,1,"10379955",1999,"The fungicide carbendazim induces meiotic micronuclei in the spermatids of the rat testis.","10379955","carbendazim","Seminiferous Tubules",1,1,1]
["carbendazim","Seminiferous Tubules",0,1,"1293130",1992,"Acute and long-term effects of a single dose of the fungicide carbendazim (methyl 2-benzimidazole carbamate) on the male reproductive system in the rat.","1293130","carbendazim","Seminiferous Tubules",1,1,1]
["carbendazim","Seminiferous Tubules",1,1,"15141104",2004,"2,5-hexanedione and carbendazim coexposure synergistically disrupts rat spermatogenesis despite opposing molecular effects on microtubules.","15141104","carbendazim","Seminiferous Tubules",1,1,1]
["carbendazim","Sertoli Cells",1,1,"12561966",2002,"Male reproductive toxic effects of carbendazim: hitherto unreported targets in testis.","12561966","carbendazim","Sertoli Cells",1,1,1]
["carbendazim","Sertoli Cells",1,1,"15141104",2004,"2,5-hexanedione and carbendazim coexposure synergistically disrupts rat spermatogenesis despite opposing molecular effects on microtubules.","15141104","carbendazim","Sertoli Cells",1,1,1]
["carbendazim","Sertoli Cells",1,1,"15237525",2004,"Nature is complex: our orchestra seats at the most wonderful show on earth.","15237525","carbendazim","Sertoli Cells",1,1,1]
["carbendazim","Sperm Count",1,1,"11831377",2001,"Spermatotoxic effect of carbendazim.","11831377","carbendazim","Sperm Count",1,1,1]
["carbendazim","Sperm Count",0,1,"1293130",1992,"Acute and long-term effects of a single dose of the fungicide carbendazim (methyl 2-benzimidazole carbamate) on the male reproductive system in the rat.","1293130","carbendazim","Sperm Count",1,1,1]
["carbendazim","Sperm Count",1,1,"19318503",2009,"Effects of subchronic exposure to carbendazim on spermatogenesis and fertility in male rats.","19318503","carbendazim","Sperm Count",1,1,1]
["carbendazim","Sperm Count",1,1,"2227156",1990,"Carbendazim-induced alterations of reproductive development and function in the rat and hamster.","2227156","carbendazim","Sperm Count",1,1,1]
["carbendazim","Sperm Head",1,1,"3560261",1987,"Effects of the fungicide methyl-benzimidazol-2-yl carbamate (MBC) on mouse germ cells as determined by flow cytometry.","3560261","carbendazim","Sperm Head",1,1,1]
["carbendazim","Sperm Motility",1,1,"11831377",2001,"Spermatotoxic effect of carbendazim.","11831377","carbendazim","Sperm Motility",1,1,1]
["carbendazim","Sperm Motility",1,1,"19318503",2009,"Effects of subchronic exposure to carbendazim on spermatogenesis and fertility in male rats.","19318503","carbendazim","Sperm Motility",1,1,1]
["carbendazim","Sperm Motility",1,1,"2227156",1990,"Carbendazim-induced alterations of reproductive development and function in the rat and hamster.","2227156","carbendazim","Sperm Motility",1,1,1]
["carbendazim","Spermatids",1,1,"10379955",1999,"The fungicide carbendazim induces meiotic micronuclei in the spermatids of the rat testis.","10379955","carbendazim","Spermatids",1,1,1]
["carbendazim","Spermatids",1,1,"12561966",2002,"Male reproductive toxic effects of carbendazim: hitherto unreported targets in testis.","12561966","carbendazim","Spermatids",1,1,1]
["carbendazim","Spermatids",0,1,"9066915",1997,"Effects of carbendazim (methyl 2-benzimidazole carbamate; MBC) on meiotic spermatocytes and subsequent spermiogenesis in the rat testis.","9066915","carbendazim","Spermatids",1,1,1]
["carbendazim","Spermatids",1,1,"9281846",1997,"Further observations on carbendazim-induced abnormalities of spermatid morphology in rats.","9281846","carbendazim","Spermatids",1,1,1]
["carbendazim","Spermatids",0,1,"9990427",1998,"Spermatids of prepubertal male rats are susceptible to carbendazim during early spermiogenesis.","9990427","carbendazim","Spermatids",1,1,1]
["carbendazim","Spermatocytes",1,1,"12561966",2002,"Male reproductive toxic effects of carbendazim: hitherto unreported targets in testis.","12561966","carbendazim","Spermatocytes",1,1,1]
["carbendazim","Spermatocytes",0,1,"9066915",1997,"Effects of carbendazim (methyl 2-benzimidazole carbamate; MBC) on meiotic spermatocytes and subsequent spermiogenesis in the rat testis.","9066915","carbendazim","Spermatocytes",1,1,1]
["carbendazim","Spermatogenesis",1,1,"11411049",2000,"Carbendazim generates symplasts in rat spermatogenic clones.","11411049","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogenesis",1,1,"12561966",2002,"Male reproductive toxic effects of carbendazim: hitherto unreported targets in testis.","12561966","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogenesis",1,1,"15141104",2004,"2,5-hexanedione and carbendazim coexposure synergistically disrupts rat spermatogenesis despite opposing molecular effects on microtubules.","15141104","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogenesis",1,1,"15237525",2004,"Nature is complex: our orchestra seats at the most wonderful show on earth.","15237525","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogenesis",1,1,"19318503",2009,"Effects of subchronic exposure to carbendazim on spermatogenesis and fertility in male rats.","19318503","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogenesis",0,1,"19593989",2009,"[Carbendazim affects testicular development and spermatogenic function in rats].","19593989","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogenesis",1,1,"22382377",2012,"Molecular alterations underlying the enhanced disruption of spermatogenesis by 2,5-hexanedione and carbendazim co-exposure.","22382377","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogenesis",1,1,"6618238",1983,"[Gonadotoxic action of methyl-N-(2-benzimidazolyl)carbamate with a probability assessment of its effective concentrations].","6618238","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogenesis",0,1,"9066915",1997,"Effects of carbendazim (methyl 2-benzimidazole carbamate; MBC) on meiotic spermatocytes and subsequent spermiogenesis in the rat testis.","9066915","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogenesis",1,1,"9724464",1998,"Carbendazim-induced abnormal development of the acrosome during early phases of spermiogenesis in the rat testis.","9724464","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogenesis",0,1,"9990427",1998,"Spermatids of prepubertal male rats are susceptible to carbendazim during early spermiogenesis.","9990427","carbendazim","Spermatogenesis",1,1,1]
["carbendazim","Spermatogonia",1,1,"10567038",1999,"Increased frequencies of diploid sperm detected by multicolour FISH after treatment of rats with carbendazim without micronucleus induction in peripheral blood erythrocytes.","10567038","carbendazim","Spermatogonia",1,1,1]
["carbendazim","Spermatogonia",1,1,"6484457",1984,"[Effect of carbendazyme (MBC) on spermatogonia of laboratory animals].","6484457","carbendazim","Spermatogonia",1,1,1]
["carbendazim","Spermatozoa",1,1,"10567038",1999,"Increased frequencies of diploid sperm detected by multicolour FISH after treatment of rats with carbendazim without micronucleus induction in peripheral blood erythrocytes.","10567038","carbendazim","Spermatozoa",1,1,1]
["carbendazim","Spermatozoa",1,1,"11406186",2001,"Continuing ability of the rodent bone marrow micronucleus assay to act as a predictor of the possible germ cell mutagenicity of chemicals.","11406186","carbendazim","Spermatozoa",1,1,1]
["carbendazim","Spermatozoa",1,1,"11831377",2001,"Spermatotoxic effect of carbendazim.","11831377","carbendazim","Spermatozoa",1,1,1]
["carbendazim","Spermatozoa",1,1,"12106657",2002,"Induction of aneuploidy in male mouse germ cells detected by the sperm-FISH assay: a review of the present data base.","12106657","carbendazim","Spermatozoa",1,1,1]
["carbendazim","Spermatozoa",0,1,"1293130",1992,"Acute and long-term effects of a single dose of the fungicide carbendazim (methyl 2-benzimidazole carbamate) on the male reproductive system in the rat.","1293130","carbendazim","Spermatozoa",1,1,1]
["carbendazim","Spermatozoa",1,1,"2227156",1990,"Carbendazim-induced alterations of reproductive development and function in the rat and hamster.","2227156","carbendazim","Spermatozoa",1,1,1]
["carbendazim","Spermatozoa",1,1,"22952946",2012,"Sperm mRNA transcripts are indicators of sub-chronic low dose testicular injury in the Fischer 344 rat.","22952946","carbendazim","Spermatozoa",1,1,1]
["carbendazim","Spermatozoa",1,1,"2666989",1989,"Correlation of sperm and endocrine measures with reproductive success in rodents.","2666989","carbendazim","Spermatozoa",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I644,I644)","v":"carbendazim"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J644,J644)","v":"Spermatozoa"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H644,H644)","v":"3560261"},1987,"Effects of the fungicide methyl-benzimidazol-2-yl carbamate (MBC) on mouse germ cells as determined by flow cytometry.","3560261","carbendazim","Spermatozoa",1,1,1]
["carbendazim","Spermatozoa",1,1,"6484457",1984,"[Effect of carbendazyme (MBC) on spermatogonia of laboratory animals].","6484457","carbendazim","Spermatozoa",1,1,1]
["carbendazim","Spermatozoa",0,1,"9990427",1998,"Spermatids of prepubertal male rats are susceptible to carbendazim during early spermiogenesis.","9990427","carbendazim","Spermatozoa",1,1,1]
["carbendazim","Testis",1,1,"10379955",1999,"The fungicide carbendazim induces meiotic micronuclei in the spermatids of the rat testis.","10379955","carbendazim","Testis",1,1,1]
["carbendazim","Testis",1,1,"11411049",2000,"Carbendazim generates symplasts in rat spermatogenic clones.","11411049","carbendazim","Testis",1,1,1]
["carbendazim","Testis",1,1,"12561966",2002,"Male reproductive toxic effects of carbendazim: hitherto unreported targets in testis.","12561966","carbendazim","Testis",1,1,1]
["carbendazim","Testis",0,1,"1293130",1992,"Acute and long-term effects of a single dose of the fungicide carbendazim (methyl 2-benzimidazole carbamate) on the male reproductive system in the rat.","1293130","carbendazim","Testis",1,1,1]
["carbendazim","Testis",1,1,"15141104",2004,"2,5-hexanedione and carbendazim coexposure synergistically disrupts rat spermatogenesis despite opposing molecular effects on microtubules.","15141104","carbendazim","Testis",1,1,1]
["carbendazim","Testis",1,1,"19318503",2009,"Effects of subchronic exposure to carbendazim on spermatogenesis and fertility in male rats.","19318503","carbendazim","Testis",1,1,1]
["carbendazim","Testis",0,1,"19593989",2009,"[Carbendazim affects testicular development and spermatogenic function in rats].","19593989","carbendazim","Testis",1,1,1]
["carbendazim","Testis",1,1,"22382377",2012,"Molecular alterations underlying the enhanced disruption of spermatogenesis by 2,5-hexanedione and carbendazim co-exposure.","22382377","carbendazim","Testis",1,1,1]
["carbendazim","Testis",1,1,"22952946",2012,"Sperm mRNA transcripts are indicators of sub-chronic low dose testicular injury in the Fischer 344 rat.","22952946","carbendazim","Testis",1,1,1]
["carbendazim","Testis",1,1,"2666989",1989,"Correlation of sperm and endocrine measures with reproductive success in rodents.","2666989","carbendazim","Testis",1,1,1]
["carbendazim","Testis",1,1,"3560261",1987,"Effects of the fungicide methyl-benzimidazol-2-yl carbamate (MBC) on mouse germ cells as determined by flow cytometry.","3560261","carbendazim","Testis",1,1,1]
["carbendazim","Testis",1,1,"6618238",1983,"[Gonadotoxic action of methyl-N-(2-benzimidazolyl)carbamate with a probability assessment of its effective concentrations].","6618238","carbendazim","Testis",1,1,1]
["carbendazim","Testis",0,1,"9066915",1997,"Effects of carbendazim (methyl 2-benzimidazole carbamate; MBC) on meiotic spermatocytes and subsequent spermiogenesis in the rat testis.","9066915","carbendazim","Testis",1,1,1]
["carbendazim","Testis",1,1,"9719423",1998,"In vivo studies on possible adverse effects on reproduction of the fungicide methyl thiophanate.","9719423","carbendazim","Testis",1,1,1]
["Chlorpromazine","Adrenogenital Syndrome",0,0,"14096647",1963,"[ON THE PITUITARY-ADRENAL FEED-BACK TEST].","14096647","Chlorpromazine","Adrenogenital Syndrome",1,1,1]
["Chlorpromazine","Cryptorchidism",0,1,"6151560",1984,"Prolactin response to chlorpromazine in hypogonadism.","6151560","Chlorpromazine","Cryptorchidism",1,1,1]
["Chlorpromazine","Epididymis",0,0,"14125929",1964,"THE EFFECTS OF PROLONGED CHLORPROMAZINE ADMINISTRATION ON THE REPRODUCTIVE ORGANS IN THE MALE GOAT.","14125929","Chlorpromazine","Epididymis",1,1,1]
["Chlorpromazine","Genitalia, Male",0,1,"4741322",1973,"Effect of the neonatal administration of a single dose of chlorpromazine on the subsequent sexual development of male mice.","4741322","Chlorpromazine","Genitalia, Male",1,1,1]
["Chlorpromazine","Penis",1,1,"3573170",1987,"Priapism induced by chlorpromazine and trazodone: mechanism of action.","3573170","Chlorpromazine","Penis",1,1,1]
["Chlorpromazine","Prostate",0,1,"10558921",1999,"The antagonistic effect of chlorpromazine on cadmium toxicity.","10558921","Chlorpromazine","Prostate",1,1,1]
["Chlorpromazine","Seminal Vesicles",0,1,"10558921",1999,"The antagonistic effect of chlorpromazine on cadmium toxicity.","10558921","Chlorpromazine","Seminal Vesicles",1,1,1]
["Chlorpromazine","Seminal Vesicles",0,0,"14125929",1964,"THE EFFECTS OF PROLONGED CHLORPROMAZINE ADMINISTRATION ON THE REPRODUCTIVE ORGANS IN THE MALE GOAT.","14125929","Chlorpromazine","Seminal Vesicles",1,1,1]
["Chlorpromazine","Seminal Vesicles",0,1,"4741322",1973,"Effect of the neonatal administration of a single dose of chlorpromazine on the subsequent sexual development of male mice.","4741322","Chlorpromazine","Seminal Vesicles",1,1,1]
["Chlorpromazine","Seminiferous Tubules",0,1,"6653838",1983,"Gametogenesis in chlorpromazine-treated BALBc mice.","6653838","Chlorpromazine","Seminiferous Tubules",1,1,1]
["Chlorpromazine","Sperm Count",0,1,"10558921",1999,"The antagonistic effect of chlorpromazine on cadmium toxicity.","10558921","Chlorpromazine","Sperm Count",1,1,1]
["Chlorpromazine","Sperm Count",0,1,"2969221",1988,"Influence of chlorpromazine on motility and calcium uptake of boar sperm.","2969221","Chlorpromazine","Sperm Count",1,1,1]
["Chlorpromazine","Sperm Motility",0,1,"10558921",1999,"The antagonistic effect of chlorpromazine on cadmium toxicity.","10558921","Chlorpromazine","Sperm Motility",1,1,1]
["Chlorpromazine","Sperm Motility",0,1,"2969221",1988,"Influence of chlorpromazine on motility and calcium uptake of boar sperm.","2969221","Chlorpromazine","Sperm Motility",1,1,1]
["Chlorpromazine","Sperm Motility",0,1,"6667751",1983,"Motility and fertilization capability of mouse and toad (Xenopus laevis) chlorpromazine-treated spermatozoa.","6667751","Chlorpromazine","Sperm Motility",1,1,1]
["Chlorpromazine","Spermatogenesis",0,1,"4741322",1973,"Effect of the neonatal administration of a single dose of chlorpromazine on the subsequent sexual development of male mice.","4741322","Chlorpromazine","Spermatogenesis",1,1,1]
["Chlorpromazine","Spermatogenesis",0,1,"6653838",1983,"Gametogenesis in chlorpromazine-treated BALBc mice.","6653838","Chlorpromazine","Spermatogenesis",1,1,1]
["Chlorpromazine","Spermatozoa",0,1,"10558921",1999,"The antagonistic effect of chlorpromazine on cadmium toxicity.","10558921","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",0,0,"14101201",1963,"EFFECT OF TRANQUILIZERS ON LIBIDO, SPERM PRODUCTION AND IN VITRO SPERM SURVIVAL IN DOGS.","14101201","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",0,0,"14125929",1964,"THE EFFECTS OF PROLONGED CHLORPROMAZINE ADMINISTRATION ON THE REPRODUCTIVE ORGANS IN THE MALE GOAT.","14125929","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",0,1,"1530368",1992,"Effect of chlorpromazine on bovine sperm respiration.","1530368","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",0,1,"19032433",2010,"Ascorbic acid, catalase and chlorpromazine reduce cryopreservation-induced damages to crossbred bull spermatozoa.","19032433","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",0,1,"2969221",1988,"Influence of chlorpromazine on motility and calcium uptake of boar sperm.","2969221","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",0,1,"4400232",1970,"Effects of psychoactive drugs on sperm motility.","4400232","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",1,1,"4541114",1973,"The sea urchin egg as a testing object in toxicology.","4541114","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",0,1,"5067291",1972,"[Comparison of the effects of chlorpromazine and carbon dioxide on survival of bovine spermatozoa preserved in IVT egg yolk diluent].","5067291","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",0,1,"5471856",1970,"Effect of a single injection of chlorpromazine into infant male rats on subsequent gonadotrophin secretion.","5471856","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",0,1,"6653838",1983,"Gametogenesis in chlorpromazine-treated BALBc mice.","6653838","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",0,1,"6667751",1983,"Motility and fertilization capability of mouse and toad (Xenopus laevis) chlorpromazine-treated spermatozoa.","6667751","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Spermatozoa",1,1,"6669638",1983,"Photochemical damage to DNA treated with chlorpromazine and near UV radiation under aerobic and anaerobic conditions.","6669638","Chlorpromazine","Spermatozoa",1,1,1]
["Chlorpromazine","Testis",0,1,"10558921",1999,"The antagonistic effect of chlorpromazine on cadmium toxicity.","10558921","Chlorpromazine","Testis",1,1,1]
["Chlorpromazine","Testis",0,0,"14125929",1964,"THE EFFECTS OF PROLONGED CHLORPROMAZINE ADMINISTRATION ON THE REPRODUCTIVE ORGANS IN THE MALE GOAT.","14125929","Chlorpromazine","Testis",1,1,1]
["Chlorpromazine","Testis",0,1,"4741322",1973,"Effect of the neonatal administration of a single dose of chlorpromazine on the subsequent sexual development of male mice.","4741322","Chlorpromazine","Testis",1,1,1]
["Chlorpromazine","Turner Syndrome",0,0,"14096647",1963,"[ON THE PITUITARY-ADRENAL FEED-BACK TEST].","14096647","Chlorpromazine","Turner Syndrome",1,1,1]
["Chlorpromazine","Urogenital Abnormalities",1,0,"4945875",1971,"[Teratogenic effects of hyperemesis gravidarum and of the customary drugs used in its therapy].","4945875","Chlorpromazine","Urogenital Abnormalities",1,1,1]
["Chlorpromazine","Vas Deferens",0,1,"6653838",1983,"Gametogenesis in chlorpromazine-treated BALBc mice.","6653838","Chlorpromazine","Vas Deferens",1,1,1]
["Cyanamide","Testis",1,1,"3628177",1987,"A two-generation reproduction-fertility study of cyanamide in the rat.","3628177","Cyanamide","Testis",1,null,1]
["cypermethrin","Epididymis",1,1,"19500828",2009,"Beta-cypermethrin impairs reproductive function in male mice by inducing oxidative stress.","19500828","cypermethrin","Epididymis",1,null,1]
["cypermethrin","Epididymis",1,1,"19862501",2010,"Cypermethrin exposure during puberty disrupts testosterone synthesis via downregulating StAR in mouse testes.","19862501","cypermethrin","Epididymis",1,null,1]
["cypermethrin","Epididymis",1,1,"21542485",2010,"Cypermetherin toxic effects on spermatogenesis and male mouse reproductive organs.","21542485","cypermethrin","Epididymis",1,null,1]
["cypermethrin","Epididymis",0,1,"23425803",2013,"Effects of cypermethrin on male reproductive system in adult rats.","23425803","cypermethrin","Epididymis",1,null,1]
["cypermethrin","Epididymis",1,1,"24558798",2013,"Cypermethrin induced reproductive toxicity in male Wistar rats: protective role of Tribulus terrestris.","24558798","cypermethrin","Epididymis",1,null,1]
["cypermethrin","Genitalia, Male",1,1,"22147539",2013,"Toxic effects of cypermethrin on the male reproductive system: with emphasis on the androgen receptor.","22147539","cypermethrin","Genitalia, Male",1,null,1]
["cypermethrin","Leydig Cells",1,1,"19500828",2009,"Beta-cypermethrin impairs reproductive function in male mice by inducing oxidative stress.","19500828","cypermethrin","Leydig Cells",1,null,1]
["cypermethrin","Leydig Cells",1,1,"19862501",2010,"Cypermethrin exposure during puberty disrupts testosterone synthesis via downregulating StAR in mouse testes.","19862501","cypermethrin","Leydig Cells",1,null,1]
["cypermethrin","Prostate",0,1,"23425803",2013,"Effects of cypermethrin on male reproductive system in adult rats.","23425803","cypermethrin","Prostate",1,null,1]
["cypermethrin","Seminal Vesicles",1,1,"11598791",2001,"Evaluation of the toxic potentials of cypermethrin pesticide on some reproductive and fertility parameters in the male rats.","11598791","cypermethrin","Seminal Vesicles",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I708,I708)","v":"cypermethrin"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J708,J708)","v":"Seminal Vesicles"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H708,H708)","v":"18490057"},2009,"Cypermethrin effects on the adult mice seminal glands.","18490057","cypermethrin","Seminal Vesicles",1,null,1]
["cypermethrin","Seminal Vesicles",0,1,"23425803",2013,"Effects of cypermethrin on male reproductive system in adult rats.","23425803","cypermethrin","Seminal Vesicles",1,null,1]
["cypermethrin","Seminiferous Tubules",1,1,"22147539",2013,"Toxic effects of cypermethrin on the male reproductive system: with emphasis on the androgen receptor.","22147539","cypermethrin","Seminiferous Tubules",1,null,1]
["cypermethrin","Sperm Count",1,1,"11598791",2001,"Evaluation of the toxic potentials of cypermethrin pesticide on some reproductive and fertility parameters in the male rats.","11598791","cypermethrin","Sperm Count",1,null,1]
["cypermethrin","Sperm Count",1,1,"12856928",2003,"Protective role of isoflavones against the toxic effect of cypermethrin on semen quality and testosterone levels of rabbits.","12856928","cypermethrin","Sperm Count",1,null,1]
["cypermethrin","Sperm Count",1,1,"19019642",2009,"Deleterious effects of cypermethrin on semen characteristics and testes of dwarf goats (Capra hircus).","19019642","cypermethrin","Sperm Count",1,null,1]
["cypermethrin","Sperm Count",1,1,"20131380",2011,"Maternal cypermethrin exposure during lactation impairs testicular development and spermatogenesis in male mouse offspring.","20131380","cypermethrin","Sperm Count",1,null,1]
["cypermethrin","Sperm Count",1,1,"20435348",2010,"Cypermethrin reversibly alters sperm count without altering fertility in mice.","20435348","cypermethrin","Sperm Count",1,null,1]
["cypermethrin","Sperm Count",1,1,"21542485",2010,"Cypermetherin toxic effects on spermatogenesis and male mouse reproductive organs.","21542485","cypermethrin","Sperm Count",1,null,1]
["cypermethrin","Sperm Count",1,1,"22147539",2013,"Toxic effects of cypermethrin on the male reproductive system: with emphasis on the androgen receptor.","22147539","cypermethrin","Sperm Count",1,null,1]
["cypermethrin","Sperm Count",1,1,"24558798",2013,"Cypermethrin induced reproductive toxicity in male Wistar rats: protective role of Tribulus terrestris.","24558798","cypermethrin","Sperm Count",1,null,1]
["cypermethrin","Sperm Head",1,1,"24558798",2013,"Cypermethrin induced reproductive toxicity in male Wistar rats: protective role of Tribulus terrestris.","24558798","cypermethrin","Sperm Head",1,null,1]
["cypermethrin","Sperm Motility",1,1,"12856928",2003,"Protective role of isoflavones against the toxic effect of cypermethrin on semen quality and testosterone levels of rabbits.","12856928","cypermethrin","Sperm Motility",1,null,1]
["cypermethrin","Sperm Motility",1,1,"18214806",2008,"Effects of fenvalerate and cypermethrin on rat sperm motility patterns in vitro as measured by computer-assisted sperm analysis.","18214806","cypermethrin","Sperm Motility",1,null,1]
["cypermethrin","Sperm Motility",1,1,"19896529",2010,"Effects of permethrin, cypermethrin and 3-phenoxybenzoic acid on rat sperm motility in vitro evaluated with computer-assisted sperm analysis.","19896529","cypermethrin","Sperm Motility",1,null,1]
["cypermethrin","Sperm Motility",1,1,"21542485",2010,"Cypermetherin toxic effects on spermatogenesis and male mouse reproductive organs.","21542485","cypermethrin","Sperm Motility",1,null,1]
["cypermethrin","Sperm Motility",1,1,"24558798",2013,"Cypermethrin induced reproductive toxicity in male Wistar rats: protective role of Tribulus terrestris.","24558798","cypermethrin","Sperm Motility",1,null,1]
["cypermethrin","Spermatocytes",1,1,"22147539",2013,"Toxic effects of cypermethrin on the male reproductive system: with emphasis on the androgen receptor.","22147539","cypermethrin","Spermatocytes",1,null,1]
["cypermethrin","Spermatogenesis",1,1,"19019642",2009,"Deleterious effects of cypermethrin on semen characteristics and testes of dwarf goats (Capra hircus).","19019642","cypermethrin","Spermatogenesis",1,null,1]
["cypermethrin","Spermatogenesis",1,1,"19862501",2010,"Cypermethrin exposure during puberty disrupts testosterone synthesis via downregulating StAR in mouse testes.","19862501","cypermethrin","Spermatogenesis",1,null,1]
["cypermethrin","Spermatogenesis",1,1,"20131380",2011,"Maternal cypermethrin exposure during lactation impairs testicular development and spermatogenesis in male mouse offspring.","20131380","cypermethrin","Spermatogenesis",1,null,1]
["cypermethrin","Spermatogenesis",1,1,"21542485",2010,"Cypermetherin toxic effects on spermatogenesis and male mouse reproductive organs.","21542485","cypermethrin","Spermatogenesis",1,null,1]
["cypermethrin","Spermatogenesis",1,1,"22147539",2013,"Toxic effects of cypermethrin on the male reproductive system: with emphasis on the androgen receptor.","22147539","cypermethrin","Spermatogenesis",1,null,1]
["cypermethrin","Spermatogenesis",0,1,"23425803",2013,"Effects of cypermethrin on male reproductive system in adult rats.","23425803","cypermethrin","Spermatogenesis",1,null,1]
["cypermethrin","Spermatogonia",1,1,"22147539",2013,"Toxic effects of cypermethrin on the male reproductive system: with emphasis on the androgen receptor.","22147539","cypermethrin","Spermatogonia",1,null,1]
["cypermethrin","Spermatozoa",1,1,"15529877",2004,"Demonstration of sperm head shape abnormality and clastogenic potential of cypermethrin.","15529877","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Spermatozoa",1,1,"18214806",2008,"Effects of fenvalerate and cypermethrin on rat sperm motility patterns in vitro as measured by computer-assisted sperm analysis.","18214806","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Spermatozoa",1,1,"19019642",2009,"Deleterious effects of cypermethrin on semen characteristics and testes of dwarf goats (Capra hircus).","19019642","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Spermatozoa",1,1,"19500828",2009,"Beta-cypermethrin impairs reproductive function in male mice by inducing oxidative stress.","19500828","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Spermatozoa",1,1,"19862501",2010,"Cypermethrin exposure during puberty disrupts testosterone synthesis via downregulating StAR in mouse testes.","19862501","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Spermatozoa",1,1,"19896529",2010,"Effects of permethrin, cypermethrin and 3-phenoxybenzoic acid on rat sperm motility in vitro evaluated with computer-assisted sperm analysis.","19896529","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Spermatozoa",1,1,"20131380",2011,"Maternal cypermethrin exposure during lactation impairs testicular development and spermatogenesis in male mouse offspring.","20131380","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Spermatozoa",1,1,"20435348",2010,"Cypermethrin reversibly alters sperm count without altering fertility in mice.","20435348","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Spermatozoa",1,1,"21542485",2010,"Cypermetherin toxic effects on spermatogenesis and male mouse reproductive organs.","21542485","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Spermatozoa",1,1,"24558798",2013,"Cypermethrin induced reproductive toxicity in male Wistar rats: protective role of Tribulus terrestris.","24558798","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Spermatozoa",1,1,"3376150",1988,"Genotoxic effects of a synthetic pyrethroid insecticide, cypermethrin, in mice in vivo.","3376150","cypermethrin","Spermatozoa",1,null,1]
["cypermethrin","Testis",1,1,"11598791",2001,"Evaluation of the toxic potentials of cypermethrin pesticide on some reproductive and fertility parameters in the male rats.","11598791","cypermethrin","Testis",1,null,1]
["cypermethrin","Testis",1,1,"15529877",2004,"Demonstration of sperm head shape abnormality and clastogenic potential of cypermethrin.","15529877","cypermethrin","Testis",1,null,1]
["cypermethrin","Testis",1,1,"19019642",2009,"Deleterious effects of cypermethrin on semen characteristics and testes of dwarf goats (Capra hircus).","19019642","cypermethrin","Testis",1,null,1]
["cypermethrin","Testis",1,1,"19500828",2009,"Beta-cypermethrin impairs reproductive function in male mice by inducing oxidative stress.","19500828","cypermethrin","Testis",1,null,1]
["cypermethrin","Testis",1,1,"19862501",2010,"Cypermethrin exposure during puberty disrupts testosterone synthesis via downregulating StAR in mouse testes.","19862501","cypermethrin","Testis",1,null,1]
["cypermethrin","Testis",1,1,"20131380",2011,"Maternal cypermethrin exposure during lactation impairs testicular development and spermatogenesis in male mouse offspring.","20131380","cypermethrin","Testis",1,null,1]
["cypermethrin","Testis",1,1,"21542485",2010,"Cypermetherin toxic effects on spermatogenesis and male mouse reproductive organs.","21542485","cypermethrin","Testis",1,null,1]
["cypermethrin","Testis",1,1,"22147539",2013,"Toxic effects of cypermethrin on the male reproductive system: with emphasis on the androgen receptor.","22147539","cypermethrin","Testis",1,null,1]
["cypermethrin","Testis",0,1,"23425803",2013,"Effects of cypermethrin on male reproductive system in adult rats.","23425803","cypermethrin","Testis",1,null,1]
["cypermethrin","Testis",1,1,"24558798",2013,"Cypermethrin induced reproductive toxicity in male Wistar rats: protective role of Tribulus terrestris.","24558798","cypermethrin","Testis",1,null,1]
["DEET","Prostate",1,1,"22975477",2012,"Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations.","22975477","DEET","Prostate",1,null,1]
["DEET","Sperm Count",0,1,"6617532",1983,"DEET (N,N-diethyltoluamide) does not affect sperm number, viability and head morphology in male rats treated dermally.","6617532","DEET","Sperm Count",1,null,1]
["DEET","Sperm Head",0,1,"6617532",1983,"DEET (N,N-diethyltoluamide) does not affect sperm number, viability and head morphology in male rats treated dermally.","6617532","DEET","Sperm Head",1,null,1]
["DEET","Sperm Motility",1,1,"1264032",1976,"[Study of the remote results of the use of repellants. Report 1. Experimental study of the long-term effects of the repellant diethyltoluamide (DETA)].","1264032","DEET","Sperm Motility",1,null,1]
["DEET","Spermatozoa",1,1,"1264032",1976,"[Study of the remote results of the use of repellants. Report 1. Experimental study of the long-term effects of the repellant diethyltoluamide (DETA)].","1264032","DEET","Spermatozoa",1,null,1]
["DEET","Spermatozoa",1,1,"22975477",2012,"Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations.","22975477","DEET","Spermatozoa",1,null,1]
["DEET","Spermatozoa",0,1,"6617532",1983,"DEET (N,N-diethyltoluamide) does not affect sperm number, viability and head morphology in male rats treated dermally.","6617532","DEET","Spermatozoa",1,null,1]
["DEET","Testis",1,1,"22975477",2012,"Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations.","22975477","DEET","Testis",1,null,1]
["DEET","Testis",0,1,"6617532",1983,"DEET (N,N-diethyltoluamide) does not affect sperm number, viability and head morphology in male rats treated dermally.","6617532","DEET","Testis",1,null,1]
["Dibutyl Phthalate","Cryptorchidism",1,1,"10198273",1999,"Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.","10198273","Dibutyl Phthalate","Cryptorchidism",1,null,1]
["Dibutyl Phthalate","Cryptorchidism",1,1,"10643872",2000,"Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy.","10643872","Dibutyl Phthalate","Cryptorchidism",1,null,1]
["Dibutyl Phthalate","Cryptorchidism",0,1,"11297877",2001,"Adverse effects on development of the reproductive system in male offspring of rats given monobutyl phthalate, a metabolite of dibutyl phthalate, during late pregnancy.","11297877","Dibutyl Phthalate","Cryptorchidism",1,null,1]
["Dibutyl Phthalate","Cryptorchidism",0,1,"14978965",2003,"[Effects of prenatal exposure to phthalate ester on both testicular descent and urogenital development in rats].","14978965","Dibutyl Phthalate","Cryptorchidism",1,null,1]
["Dibutyl Phthalate","Cryptorchidism",1,1,"16037377",2005,"Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate.","16037377","Dibutyl Phthalate","Cryptorchidism",1,null,1]
["Dibutyl Phthalate","Cryptorchidism",1,1,"18621746",2008,"The orl rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure.","18621746","Dibutyl Phthalate","Cryptorchidism",1,null,1]
["Dibutyl Phthalate","Cryptorchidism",1,1,"20954080",2010,"Effects of in utero exposure to DI(n-Butyl) phthalate on development of male reproductive tracts in Sprague-Dawley rats.","20954080","Dibutyl Phthalate","Cryptorchidism",1,null,1]
["Dibutyl Phthalate","Cryptorchidism",1,1,"22864157",2012,"New Zealand Malayan war veterans' exposure to dibutylphthalate is associated with an increased incidence of cryptorchidism, hypospadias and breast cancer in their children.","22864157","Dibutyl Phthalate","Cryptorchidism",1,null,1]
["Dibutyl Phthalate","Cryptorchidism",1,1,"22960723",2012,"Comment on Carran and Shaw's \"New Zealand Malayan war veterans' exposure to dibutylphthalate\" article.","22960723","Dibutyl Phthalate","Cryptorchidism",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I772,I772)","v":"Dibutyl Phthalate"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J772,J772)","v":"Cryptorchidism"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H772,H772)","v":"23321895"},2012,"Increases in disease in Malayan war veterans' children may be misleading.","23321895","Dibutyl Phthalate","Cryptorchidism",1,null,1]
["Dibutyl Phthalate","Epididymis",1,1,"12851105",2003,"Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to Di(n-butyl) phthalate.","12851105","Dibutyl Phthalate","Epididymis",1,null,1]
["Dibutyl Phthalate","Epididymis",1,1,"15219629",2004,"Reproductive and developmental toxicity in F1 Sprague-Dawley male rats exposed to di-n-butyl phthalate in utero and during lactation and determination of its NOAEL.","15219629","Dibutyl Phthalate","Epididymis",1,null,1]
["Dibutyl Phthalate","Epididymis",1,1,"20823052",2011,"Di-n-butyl phthalate (DBP) exposure induces oxidative stress in epididymis of adult rats.","20823052","Dibutyl Phthalate","Epididymis",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"10198273",1999,"Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.","10198273","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"10717378",2000,"Effects of di-n-butyl phthalate (DBP) on male reproductive development in the rat: implications for human risk assessment.","10717378","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"10788569",2000,"Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to Di(n-butyl) phthalate during late gestation.","10788569","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",0,1,"11297877",2001,"Adverse effects on development of the reproductive system in male offspring of rats given monobutyl phthalate, a metabolite of dibutyl phthalate, during late pregnancy.","11297877","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"12655036",2003,"Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or postpubertal exposure.","12655036","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"14687758",2004,"Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis.","14687758","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"14713552",2004,"Male reproductive tract lesions at 6, 12, and 18 months of age following in utero exposure to di(n-butyl) phthalate.","14713552","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"15954088",2005,"Critical window of male reproductive tract development in rats following gestational exposure to di-n-butyl phthalate.","15954088","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"17400582",2007,"Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes.","17400582","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"18706996",2008,"Diisobutyl phthalate impairs the androgen-dependent reproductive development of the male rat.","18706996","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"19585553",2009,"Reproductive toxicity and pharmacokinetics of di-n-butyl phthalate (DBP) following dietary exposure of pregnant rats.","19585553","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"20002220",2010,"Androgen action in the masculinization programming window and development of male reproductive organs.","20002220","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"20849870",2013,"Use of genomic data in risk assessment case study: I. Evaluation of the dibutyl phthalate male reproductive development toxicity data set.","20849870","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"20954080",2010,"Effects of in utero exposure to DI(n-Butyl) phthalate on development of male reproductive tracts in Sprague-Dawley rats.","20954080","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",0,1,"21657945",2011,"Differential expression of the Wnt/?-catenin pathway in the genital tubercle (GT) of fetal male rat following maternal exposure to di-n-butyl phthalate (DBP).","21657945","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"9114309",1997,"Reproductive toxicology. Di-n-butylphthalate, rats.","9114309","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Genitalia, Male",1,1,"9629619",1998,"Male reproductive tract malformations in rats following gestational and lactational exposure to Di(n-butyl) phthalate: an antiandrogenic mechanism?","9629619","Dibutyl Phthalate","Genitalia, Male",1,null,1]
["Dibutyl Phthalate","Gonadal Dysgenesis",1,1,"18174951",2007,"In utero exposure to di(n-butyl) phthalate and testicular dysgenesis: comparison of fetal and adult end points and their dose sensitivity.","18174951","Dibutyl Phthalate","Gonadal Dysgenesis",1,null,1]
["Dibutyl Phthalate","Gonadal Dysgenesis",1,1,"20002220",2010,"Androgen action in the masculinization programming window and development of male reproductive organs.","20002220","Dibutyl Phthalate","Gonadal Dysgenesis",1,null,1]
["Dibutyl Phthalate","Gonadal Dysgenesis",1,1,"21868749",2012,"Induction and persistence of abnormal testicular germ cells following gestational exposure to di-(n-butyl) phthalate in p53-null mice.","21868749","Dibutyl Phthalate","Gonadal Dysgenesis",1,null,1]
["Dibutyl Phthalate","Hypospadias",0,1,"14978965",2003,"[Effects of prenatal exposure to phthalate ester on both testicular descent and urogenital development in rats].","14978965","Dibutyl Phthalate","Hypospadias",1,null,1]
["Dibutyl Phthalate","Hypospadias",1,1,"17343970",2007,"Study on developmental abnormalities in hypospadiac male rats induced by maternal exposure to di-n-butyl phthalate (DBP).","17343970","Dibutyl Phthalate","Hypospadias",1,null,1]
["Dibutyl Phthalate","Hypospadias",1,1,"19464577",2009,"Molecular and toxicologic research in newborn hypospadiac male rats following in utero exposure to di-n-butyl phthalate (DBP).","19464577","Dibutyl Phthalate","Hypospadias",1,null,1]
["Dibutyl Phthalate","Hypospadias",1,1,"20954080",2010,"Effects of in utero exposure to DI(n-Butyl) phthalate on development of male reproductive tracts in Sprague-Dawley rats.","20954080","Dibutyl Phthalate","Hypospadias",1,null,1]
["Dibutyl Phthalate","Hypospadias",1,1,"22273727",2012,"The role of androgen-induced growth factor (FGF8) on genital tubercle development in a hypospadiac male rat model of prenatal exposure to di-n-butyl phthalate.","22273727","Dibutyl Phthalate","Hypospadias",1,null,1]
["Dibutyl Phthalate","Hypospadias",1,1,"22864157",2012,"New Zealand Malayan war veterans' exposure to dibutylphthalate is associated with an increased incidence of cryptorchidism, hypospadias and breast cancer in their children.","22864157","Dibutyl Phthalate","Hypospadias",1,null,1]
["Dibutyl Phthalate","Hypospadias",1,1,"22960723",2012,"Comment on Carran and Shaw's \"New Zealand Malayan war veterans' exposure to dibutylphthalate\" article.","22960723","Dibutyl Phthalate","Hypospadias",1,null,1]
["Dibutyl Phthalate","Hypospadias",1,1,"23321895",2012,"Increases in disease in Malayan war veterans' children may be misleading.","23321895","Dibutyl Phthalate","Hypospadias",1,null,1]
["Dibutyl Phthalate","Leydig Cell Tumor",1,1,"14713552",2004,"Male reproductive tract lesions at 6, 12, and 18 months of age following in utero exposure to di(n-butyl) phthalate.","14713552","Dibutyl Phthalate","Leydig Cell Tumor",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"11934529",2002,"Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate.","11934529","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"12700402",2003,"Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate.","12700402","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",0,1,"12832361",2003,"Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate.","12832361","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"15539561",2005,"Abnormal Leydig Cell aggregation in the fetal testis of rats exposed to di (n-butyl) phthalate and its possible role in testicular dysgenesis.","15539561","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"16037377",2005,"Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate.","16037377","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"16458459",2006,"Diisobutyl phthalate has comparable anti-androgenic effects to di-n-butyl phthalate in fetal rat testis.","16458459","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"16466534",2006,"Cellular origins of testicular dysgenesis in rats exposed in utero to di(n-butyl) phthalate.","16466534","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"17431488",2007,"Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the human.","17431488","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"18174951",2007,"In utero exposure to di(n-butyl) phthalate and testicular dysgenesis: comparison of fetal and adult end points and their dose sensitivity.","18174951","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"19295080",2008,"Effect on histological and sperm kinetics in DBP exposed Wistar rats.","19295080","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"19903717",2010,"Induction of spermatogenic cell apoptosis in prepubertal rat testes irrespective of testicular steroidogenesis: a possible estrogenic effect of di(n-butyl) phthalate.","19903717","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"21266533",2011,"Species-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathways.","21266533","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"22968287",2013,"Atypical Leydig cell hyperplasia in adult rats with low T and high LH induced by prenatal Di(n-butyl) phthalate exposure.","22968287","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"23314658",2013,"Brief maternal exposure of rats to the xenobiotics dibutyl phthalate or diethylstilbestrol alters adult-type Leydig cell development in male offspring.","23314658","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Leydig Cells",1,1,"23416961",2013,"Male Sprague-Dawley rats exposed to in utero di(n-butyl) phthalate: dose dependent and age-related morphological changes in Leydig cell smooth endoplasmic reticulum.","23416961","Dibutyl Phthalate","Leydig Cells",1,null,1]
["Dibutyl Phthalate","Penis",1,1,"20002220",2010,"Androgen action in the masculinization programming window and development of male reproductive organs.","20002220","Dibutyl Phthalate","Penis",1,null,1]
["Dibutyl Phthalate","Penis",1,1,"22273727",2012,"The role of androgen-induced growth factor (FGF8) on genital tubercle development in a hypospadiac male rat model of prenatal exposure to di-n-butyl phthalate.","22273727","Dibutyl Phthalate","Penis",1,null,1]
["Dibutyl Phthalate","Penis",1,1,"9074889",1997,"Reproductive toxicity of di-n-butylphthalate in a continuous breeding protocol in Sprague-Dawley rats.","9074889","Dibutyl Phthalate","Penis",1,null,1]
["Dibutyl Phthalate","Prostate",0,1,"14978965",2003,"[Effects of prenatal exposure to phthalate ester on both testicular descent and urogenital development in rats].","14978965","Dibutyl Phthalate","Prostate",1,null,1]
["Dibutyl Phthalate","Prostate",1,1,"19549552",2009,"Long-term effects of developmental exposure to di-n-butyl-phthalate (DBP) on rat prostate: proliferative and inflammatory disorders and a possible role of androgens.","19549552","Dibutyl Phthalate","Prostate",1,null,1]
["Dibutyl Phthalate","Prostate",1,1,"20002220",2010,"Androgen action in the masculinization programming window and development of male reproductive organs.","20002220","Dibutyl Phthalate","Prostate",1,null,1]
["Dibutyl Phthalate","Seminal Vesicles",1,1,"20002220",2010,"Androgen action in the masculinization programming window and development of male reproductive organs.","20002220","Dibutyl Phthalate","Seminal Vesicles",1,null,1]
["Dibutyl Phthalate","Seminiferous Tubules",0,1,"12832361",2003,"Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate.","12832361","Dibutyl Phthalate","Seminiferous Tubules",1,null,1]
["Dibutyl Phthalate","Seminiferous Tubules",1,1,"15539561",2005,"Abnormal Leydig Cell aggregation in the fetal testis of rats exposed to di (n-butyl) phthalate and its possible role in testicular dysgenesis.","15539561","Dibutyl Phthalate","Seminiferous Tubules",1,null,1]
["Dibutyl Phthalate","Seminiferous Tubules",1,1,"19165735",2009,"Dose-dependent effects on cell proliferation, seminiferous tubules, and male germ cells in the fetal rat testis following exposure to di(n-butyl) phthalate.","19165735","Dibutyl Phthalate","Seminiferous Tubules",1,null,1]
["Dibutyl Phthalate","Seminiferous Tubules",1,1,"19295080",2008,"Effect on histological and sperm kinetics in DBP exposed Wistar rats.","19295080","Dibutyl Phthalate","Seminiferous Tubules",1,null,1]
["Dibutyl Phthalate","Seminiferous Tubules",0,1,"20304454",2010,"Single administration of di(n-butyl) phthalate delays spermatogenesis in prepubertal rats.","20304454","Dibutyl Phthalate","Seminiferous Tubules",1,null,1]
["Dibutyl Phthalate","Sertoli Cells",0,1,"12832361",2003,"Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate.","12832361","Dibutyl Phthalate","Sertoli Cells",1,null,1]
["Dibutyl Phthalate","Sertoli Cells",1,1,"15901642",2005,"Exposure in utero to di(n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact.","15901642","Dibutyl Phthalate","Sertoli Cells",1,null,1]
["Dibutyl Phthalate","Sertoli Cells",1,1,"16458459",2006,"Diisobutyl phthalate has comparable anti-androgenic effects to di-n-butyl phthalate in fetal rat testis.","16458459","Dibutyl Phthalate","Sertoli Cells",1,null,1]
["Dibutyl Phthalate","Sertoli Cells",1,1,"16466534",2006,"Cellular origins of testicular dysgenesis in rats exposed in utero to di(n-butyl) phthalate.","16466534","Dibutyl Phthalate","Sertoli Cells",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I836,I836)","v":"Dibutyl Phthalate"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J836,J836)","v":"Sertoli Cells"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H836,H836)","v":"20331591"},2010,"Di(n-butyl) phthalate induces vimentin filaments disruption in rat sertoli cells: a possible relation with spermatogenic cell apoptosis.","20331591","Dibutyl Phthalate","Sertoli Cells",1,null,1]
["Dibutyl Phthalate","Sertoli Cells",0,1,"20392824",2010,"Prenatal plus postnatal exposure to Di(n-Butyl) phthalate and/or flutamide markedly reduces final sertoli cell number in the rat.","20392824","Dibutyl Phthalate","Sertoli Cells",1,null,1]
["Dibutyl Phthalate","Sertoli Cells",1,1,"20560449",2010,"Effects of di-iso-butyl phthalate on testes of prepubertal rats and mice.","20560449","Dibutyl Phthalate","Sertoli Cells",1,null,1]
["Dibutyl Phthalate","Sertoli Cells",1,1,"23766129",2013,"Prepubertal mouse testis growth and maturation and androgen production are acutely sensitive to di-n-butyl phthalate.","23766129","Dibutyl Phthalate","Sertoli Cells",1,null,1]
["Dibutyl Phthalate","Sertoli Cells",1,1,"8376724",1993,"Mechanism of testicular atrophy induced by di-n-butyl phthalate in rats. Part 4. Changes in the activity of succinate dehydrogenase and the levels of transferrin and ferritin in the Sertoli and germ cells.","8376724","Dibutyl Phthalate","Sertoli Cells",1,null,1]
["Dibutyl Phthalate","Sperm Count",1,1,"12655036",2003,"Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or postpubertal exposure.","12655036","Dibutyl Phthalate","Sperm Count",1,null,1]
["Dibutyl Phthalate","Sperm Count",1,1,"15219629",2004,"Reproductive and developmental toxicity in F1 Sprague-Dawley male rats exposed to di-n-butyl phthalate in utero and during lactation and determination of its NOAEL.","15219629","Dibutyl Phthalate","Sperm Count",1,null,1]
["Dibutyl Phthalate","Sperm Count",1,1,"16916955",2006,"Acute and long-term effects of in utero exposure of rats to di(n-butyl) phthalate on testicular germ cell development and proliferation.","16916955","Dibutyl Phthalate","Sperm Count",1,null,1]
["Dibutyl Phthalate","Sperm Count",1,1,"22489061",2014,"Prenatal di-n-butyl phthalate exposure alters reproductive functions at adulthood in male rats.","22489061","Dibutyl Phthalate","Sperm Count",1,null,1]
["Dibutyl Phthalate","Sperm Count",1,1,"24213843",2014,"Effects of in utero di-butyl phthalate and butyl benzyl phthalate exposure on offspring development and male reproduction of rat.","24213843","Dibutyl Phthalate","Sperm Count",1,null,1]
["Dibutyl Phthalate","Sperm Count",1,1,"9074889",1997,"Reproductive toxicity of di-n-butylphthalate in a continuous breeding protocol in Sprague-Dawley rats.","9074889","Dibutyl Phthalate","Sperm Count",1,null,1]
["Dibutyl Phthalate","Sperm Count",1,1,"9114309",1997,"Reproductive toxicology. Di-n-butylphthalate, rats.","9114309","Dibutyl Phthalate","Sperm Count",1,null,1]
["Dibutyl Phthalate","Sperm Head",1,1,"22108425",2011,"Developmental toxicity in mice following paternal exposure to Di-N-butyl-phthalate (DBP).","22108425","Dibutyl Phthalate","Sperm Head",1,null,1]
["Dibutyl Phthalate","Sperm Motility",1,1,"17214610",2007,"Curcumin and kolaviron ameliorate di-n-butylphthalate-induced testicular damage in rats.","17214610","Dibutyl Phthalate","Sperm Motility",1,null,1]
["Dibutyl Phthalate","Sperm Motility",1,1,"20551087",2011,"Environmental and experimental exposure of phthalate esters: the toxicological consequence on human sperm.","20551087","Dibutyl Phthalate","Sperm Motility",1,null,1]
["Dibutyl Phthalate","Sperm Motility",1,1,"20563931",2010,"Functional and morphological reproductive aspects in male rats exposed to di-n-butyl phthalate (DBP) in utero and during lactation.","20563931","Dibutyl Phthalate","Sperm Motility",1,null,1]
["Dibutyl Phthalate","Sperm Motility",1,1,"22489061",2014,"Prenatal di-n-butyl phthalate exposure alters reproductive functions at adulthood in male rats.","22489061","Dibutyl Phthalate","Sperm Motility",1,null,1]
["Dibutyl Phthalate","Sperm Motility",1,1,"24213843",2014,"Effects of in utero di-butyl phthalate and butyl benzyl phthalate exposure on offspring development and male reproduction of rat.","24213843","Dibutyl Phthalate","Sperm Motility",1,null,1]
["Dibutyl Phthalate","Spermatids",0,1,"20304454",2010,"Single administration of di(n-butyl) phthalate delays spermatogenesis in prepubertal rats.","20304454","Dibutyl Phthalate","Spermatids",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"12655036",2003,"Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or postpubertal exposure.","12655036","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"15659570",2005,"Subchronic exposure to low concentrations of di-n-butyl phthalate disrupts spermatogenesis in Xenopus laevis frogs.","15659570","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"16002344",2005,"Effects of selected xenoestrogens on liver peroxisomes, vitellogenin levels and spermatogenic cell proliferation in male zebrafish.","16002344","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"16916955",2006,"Acute and long-term effects of in utero exposure of rats to di(n-butyl) phthalate on testicular germ cell development and proliferation.","16916955","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"17379376",2007,"Identification of differentially expressed genes in the testis of Sprague-Dawley rats treated with di(n-butyl) phthalate.","17379376","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"19903717",2010,"Induction of spermatogenic cell apoptosis in prepubertal rat testes irrespective of testicular steroidogenesis: a possible estrogenic effect of di(n-butyl) phthalate.","19903717","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",0,1,"20304454",2010,"Single administration of di(n-butyl) phthalate delays spermatogenesis in prepubertal rats.","20304454","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"20331591",2010,"Di(n-butyl) phthalate induces vimentin filaments disruption in rat sertoli cells: a possible relation with spermatogenic cell apoptosis.","20331591","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"21337613",2011,"Evidence suggesting that di-n-butyl phthalate has antiandrogenic effects in fish.","21337613","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"2365410",1990,"Testicular toxicity of di-n-butyl phthalate in adult rats: effect on marker enzymes of spermatogenesis.","2365410","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"23766129",2013,"Prepubertal mouse testis growth and maturation and androgen production are acutely sensitive to di-n-butyl phthalate.","23766129","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"2391408",1990,"Mechanism of testicular atrophy induced by di-n-butyl phthalate in rats. Part 2. The effects on some testicular enzymes.","2391408","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogenesis",1,1,"24213843",2014,"Effects of in utero di-butyl phthalate and butyl benzyl phthalate exposure on offspring development and male reproduction of rat.","24213843","Dibutyl Phthalate","Spermatogenesis",1,null,1]
["Dibutyl Phthalate","Spermatogonia",0,1,"20304454",2010,"Single administration of di(n-butyl) phthalate delays spermatogenesis in prepubertal rats.","20304454","Dibutyl Phthalate","Spermatogonia",1,null,1]
["Dibutyl Phthalate","Spermatogonia",0,1,"22252765",2011,"Di(n-butyl) phthalate has no effect on the rat prepubertal testis despite its estrogenic activity in vitro.","22252765","Dibutyl Phthalate","Spermatogonia",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"11934529",2002,"Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate.","11934529","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",0,1,"12832361",2003,"Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate.","12832361","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"15098468",2004,"[Reproductive and developmental toxicity of F1 male rats treated with DBP in utero and during lactation].","15098468","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"15219629",2004,"Reproductive and developmental toxicity in F1 Sprague-Dawley male rats exposed to di-n-butyl phthalate in utero and during lactation and determination of its NOAEL.","15219629","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"15901642",2005,"Exposure in utero to di(n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact.","15901642","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"16916955",2006,"Acute and long-term effects of in utero exposure of rats to di(n-butyl) phthalate on testicular germ cell development and proliferation.","16916955","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"17214610",2007,"Curcumin and kolaviron ameliorate di-n-butylphthalate-induced testicular damage in rats.","17214610","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"19165735",2009,"Dose-dependent effects on cell proliferation, seminiferous tubules, and male germ cells in the fetal rat testis following exposure to di(n-butyl) phthalate.","19165735","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"19295080",2008,"Effect on histological and sperm kinetics in DBP exposed Wistar rats.","19295080","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",0,1,"20304454",2010,"Single administration of di(n-butyl) phthalate delays spermatogenesis in prepubertal rats.","20304454","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"20331591",2010,"Di(n-butyl) phthalate induces vimentin filaments disruption in rat sertoli cells: a possible relation with spermatogenic cell apoptosis.","20331591","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"20551087",2011,"Environmental and experimental exposure of phthalate esters: the toxicological consequence on human sperm.","20551087","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"20560449",2010,"Effects of di-iso-butyl phthalate on testes of prepubertal rats and mice.","20560449","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"20823052",2011,"Di-n-butyl phthalate (DBP) exposure induces oxidative stress in epididymis of adult rats.","20823052","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"21868749",2012,"Induction and persistence of abnormal testicular germ cells following gestational exposure to di-(n-butyl) phthalate in p53-null mice.","21868749","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"22489061",2014,"Prenatal di-n-butyl phthalate exposure alters reproductive functions at adulthood in male rats.","22489061","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"24213843",2014,"Effects of in utero di-butyl phthalate and butyl benzyl phthalate exposure on offspring development and male reproduction of rat.","24213843","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"24576492",2014,"Di-n-butyl phthalate causes estrogenic effects in adult male Murray rainbowfish (Melanotaenia fluviatilis).","24576492","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",0,1,"2957007",1987,"Phthalate esters and semen quality parameters.","2957007","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Spermatozoa",1,1,"8376724",1993,"Mechanism of testicular atrophy induced by di-n-butyl phthalate in rats. Part 4. Changes in the activity of succinate dehydrogenase and the levels of transferrin and ferritin in the Sertoli and germ cells.","8376724","Dibutyl Phthalate","Spermatozoa",1,null,1]
["Dibutyl Phthalate","Testis",0,1,"11719706",2001,"Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate.","11719706","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"11934529",2002,"Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate.","11934529","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"12079616",2002,"Oxidative DNA damage in male Wistar rats exposed to di-n-butyl phthalate.","12079616","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"12655036",2003,"Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or postpubertal exposure.","12655036","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"12700402",2003,"Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate.","12700402","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",0,1,"12832361",2003,"Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate.","12832361","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"12851105",2003,"Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to Di(n-butyl) phthalate.","12851105","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",0,1,"14617579",2004,"Di(n-butyl) phthalate impairs cholesterol transport and steroidogenesis in the fetal rat testis through a rapid and reversible mechanism.","14617579","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"14687758",2004,"Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis.","14687758","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"14713552",2004,"Male reproductive tract lesions at 6, 12, and 18 months of age following in utero exposure to di(n-butyl) phthalate.","14713552","Dibutyl Phthalate","Testis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I900,I900)","v":"Dibutyl Phthalate"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J900,J900)","v":"Testis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H900,H900)","v":"15098468"},2004,"[Reproductive and developmental toxicity of F1 male rats treated with DBP in utero and during lactation].","15098468","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"15141095",2004,"Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate.","15141095","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"15219629",2004,"Reproductive and developmental toxicity in F1 Sprague-Dawley male rats exposed to di-n-butyl phthalate in utero and during lactation and determination of its NOAEL.","15219629","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"15659570",2005,"Subchronic exposure to low concentrations of di-n-butyl phthalate disrupts spermatogenesis in Xenopus laevis frogs.","15659570","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"15987825",2005,"Differential steroidogenic gene expression in the fetal adrenal gland versus the testis and rapid and dynamic response of the fetal testis to di(n-butyl) phthalate.","15987825","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"16037377",2005,"Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate.","16037377","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"16458459",2006,"Diisobutyl phthalate has comparable anti-androgenic effects to di-n-butyl phthalate in fetal rat testis.","16458459","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"16466534",2006,"Cellular origins of testicular dysgenesis in rats exposed in utero to di(n-butyl) phthalate.","16466534","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"16916955",2006,"Acute and long-term effects of in utero exposure of rats to di(n-butyl) phthalate on testicular germ cell development and proliferation.","16916955","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"17214610",2007,"Curcumin and kolaviron ameliorate di-n-butylphthalate-induced testicular damage in rats.","17214610","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"17379376",2007,"Identification of differentially expressed genes in the testis of Sprague-Dawley rats treated with di(n-butyl) phthalate.","17379376","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"17400582",2007,"Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes.","17400582","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"17431488",2007,"Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the human.","17431488","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"17868969",2007,"Differential expression of peroxiredoxin 6 in fetal rat testis following in utero exposure to di(n-butyl) phthalate.","17868969","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"18174951",2007,"In utero exposure to di(n-butyl) phthalate and testicular dysgenesis: comparison of fetal and adult end points and their dose sensitivity.","18174951","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",0,1,"18602967",2008,"Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats.","18602967","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"18621746",2008,"The orl rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure.","18621746","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"18817337",2008,"[Differential expression of ubiquitin C-terminal hydrolase L-1 in the rat testis following exposure to di-n-butyl phthalate in utero].","18817337","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",0,1,"19010379",2009,"Kinetics of selected di-n-butyl phthalate metabolites and fetal testosterone following repeated and single administration in pregnant rats.","19010379","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"19165735",2009,"Dose-dependent effects on cell proliferation, seminiferous tubules, and male germ cells in the fetal rat testis following exposure to di(n-butyl) phthalate.","19165735","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"19295080",2008,"Effect on histological and sperm kinetics in DBP exposed Wistar rats.","19295080","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"19549552",2009,"Long-term effects of developmental exposure to di-n-butyl-phthalate (DBP) on rat prostate: proliferative and inflammatory disorders and a possible role of androgens.","19549552","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"19585553",2009,"Reproductive toxicity and pharmacokinetics of di-n-butyl phthalate (DBP) following dietary exposure of pregnant rats.","19585553","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",0,1,"19819957",2009,"Glucocorticoids amplify dibutyl phthalate-induced disruption of testosterone production and male reproductive development.","19819957","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"19903717",2010,"Induction of spermatogenic cell apoptosis in prepubertal rat testes irrespective of testicular steroidogenesis: a possible estrogenic effect of di(n-butyl) phthalate.","19903717","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"20002220",2010,"Androgen action in the masculinization programming window and development of male reproductive organs.","20002220","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",0,1,"20304454",2010,"Single administration of di(n-butyl) phthalate delays spermatogenesis in prepubertal rats.","20304454","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"20331591",2010,"Di(n-butyl) phthalate induces vimentin filaments disruption in rat sertoli cells: a possible relation with spermatogenic cell apoptosis.","20331591","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",0,1,"20392824",2010,"Prenatal plus postnatal exposure to Di(n-Butyl) phthalate and/or flutamide markedly reduces final sertoli cell number in the rat.","20392824","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"20560449",2010,"Effects of di-iso-butyl phthalate on testes of prepubertal rats and mice.","20560449","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"20563931",2010,"Functional and morphological reproductive aspects in male rats exposed to di-n-butyl phthalate (DBP) in utero and during lactation.","20563931","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"20823052",2011,"Di-n-butyl phthalate (DBP) exposure induces oxidative stress in epididymis of adult rats.","20823052","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"20850466",2013,"Pathway modeling of microarray data: a case study of pathway activity changes in the testis following in utero exposure to dibutyl phthalate (DBP).","20850466","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"20954080",2010,"Effects of in utero exposure to DI(n-Butyl) phthalate on development of male reproductive tracts in Sprague-Dawley rats.","20954080","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"21266533",2011,"Species-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathways.","21266533","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"21332505",2011,"Effects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability.","21332505","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"21868749",2012,"Induction and persistence of abnormal testicular germ cells following gestational exposure to di-(n-butyl) phthalate in p53-null mice.","21868749","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",0,1,"22252765",2011,"Di(n-butyl) phthalate has no effect on the rat prepubertal testis despite its estrogenic activity in vitro.","22252765","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"22489061",2014,"Prenatal di-n-butyl phthalate exposure alters reproductive functions at adulthood in male rats.","22489061","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"22968287",2013,"Atypical Leydig cell hyperplasia in adult rats with low T and high LH induced by prenatal Di(n-butyl) phthalate exposure.","22968287","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"23314658",2013,"Brief maternal exposure of rats to the xenobiotics dibutyl phthalate or diethylstilbestrol alters adult-type Leydig cell development in male offspring.","23314658","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"23416961",2013,"Male Sprague-Dawley rats exposed to in utero di(n-butyl) phthalate: dose dependent and age-related morphological changes in Leydig cell smooth endoplasmic reticulum.","23416961","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"23536518",2014,"Influence of oily vehicles on fetal testis and lipid profile of rats exposed to di-butyl phthalate.","23536518","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"2365410",1990,"Testicular toxicity of di-n-butyl phthalate in adult rats: effect on marker enzymes of spermatogenesis.","2365410","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"23707436",2013,"Differential expression of peroxiredoxin 6, annexin A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1 in testis of rat fetuses after maternal exposure to di-n-butyl phthalate.","23707436","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"23766129",2013,"Prepubertal mouse testis growth and maturation and androgen production are acutely sensitive to di-n-butyl phthalate.","23766129","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"2391408",1990,"Mechanism of testicular atrophy induced by di-n-butyl phthalate in rats. Part 2. The effects on some testicular enzymes.","2391408","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"24213843",2014,"Effects of in utero di-butyl phthalate and butyl benzyl phthalate exposure on offspring development and male reproduction of rat.","24213843","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"8376724",1993,"Mechanism of testicular atrophy induced by di-n-butyl phthalate in rats. Part 4. Changes in the activity of succinate dehydrogenase and the levels of transferrin and ferritin in the Sertoli and germ cells.","8376724","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Testis",1,1,"9074889",1997,"Reproductive toxicity of di-n-butylphthalate in a continuous breeding protocol in Sprague-Dawley rats.","9074889","Dibutyl Phthalate","Testis",1,null,1]
["Dibutyl Phthalate","Urogenital Abnormalities",1,1,"12851105",2003,"Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to Di(n-butyl) phthalate.","12851105","Dibutyl Phthalate","Urogenital Abnormalities",1,null,1]
["Dichlorodiphenyl Dichloroethylene","Cryptorchidism",1,1,"11836195",2002,"Maternal serum level of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene and risk of cryptorchidism, hypospadias, and polythelia among male offspring.","11836195","Dichlorodiphenyl Dichloroethylene","Cryptorchidism",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Cryptorchidism",1,1,"15533328",2005,"Maternal serum level of the DDT metabolite DDE in relation to fetal loss in previous pregnancies.","15533328","Dichlorodiphenyl Dichloroethylene","Cryptorchidism",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Cryptorchidism",0,1,"15687061",2005,"Organochlorine pesticides and male genital anomalies in the child health and development studies.","15687061","Dichlorodiphenyl Dichloroethylene","Cryptorchidism",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Cryptorchidism",1,1,"18503055",2008,"Cryptorchidism at birth in Nice area (France) is associated with higher prenatal exposure to PCBs and DDE, as assessed by colostrum concentrations.","18503055","Dichlorodiphenyl Dichloroethylene","Cryptorchidism",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Disorders of Sex Development",1,1,"10706532",2000,"Salmonid sexual development is not consistently altered by embryonic exposure to endocrine-active chemicals.","10706532","Dichlorodiphenyl Dichloroethylene","Disorders of Sex Development",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,"16918713",2006,"Effects of perinatal combined exposure to 1,1-dichloro-2,2 bis (p-chlorophenyl) ethylene and tributyltin on male reproductive system.","16918713","Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,"17008049",2006,"Association between exposure to persistent organohalogen pollutants and epididymal and accessory sex gland function: multicentre study in Inuit and European populations.","17008049","Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,"17272288",2007,"In utero exposure to the antiandrogen 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) in relation to anogenital distance in male newborns from Chiapas, México.","17272288","Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,"9549179",1998,"Effects of p,p'-DDE on male reproductive organs in peripubertal Wistar rats following a single intraperitoneal injection.","9549179","Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,"9848123",1998,"Impaired male sexual development in perinatal Sprague-Dawley and Long-Evans hooded rats exposed in utero and lactationally to p,p'-DDE.","9848123","Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Genitalia, Male",0,1,"9882589",1999,"Interactive effects of TCDD and p,p'-DDE on male reproductive tract development in in utero and lactationally exposed rats.","9882589","Dichlorodiphenyl Dichloroethylene","Genitalia, Male",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Hypospadias",1,1,"11836195",2002,"Maternal serum level of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene and risk of cryptorchidism, hypospadias, and polythelia among male offspring.","11836195","Dichlorodiphenyl Dichloroethylene","Hypospadias",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Hypospadias",0,1,"14974286",2003,"[DDT/DDE concentrations and risk of hypospadias. Pilot case-control study].","14974286","Dichlorodiphenyl Dichloroethylene","Hypospadias",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I964,I964)","v":"Dichlorodiphenyl Dichloroethylene"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J964,J964)","v":"Hypospadias"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H964,H964)","v":"15533328"},2005,"Maternal serum level of the DDT metabolite DDE in relation to fetal loss in previous pregnancies.","15533328","Dichlorodiphenyl Dichloroethylene","Hypospadias",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Hypospadias",0,1,"15687061",2005,"Organochlorine pesticides and male genital anomalies in the child health and development studies.","15687061","Dichlorodiphenyl Dichloroethylene","Hypospadias",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Prostate",1,1,"10620483",1999,"In utero exposure to antiandrogens alters the responsiveness of the prostate to p,p'-DDE in adult rats and may induce prostatic inflammation.","10620483","Dichlorodiphenyl Dichloroethylene","Prostate",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Prostate",0,1,"14718175",2004,"Effects of perinatal simultaneous exposure to tributyltin (TBT) and p,p'-DDE [1,1-dichloro-2,2-bis(p-chlorophenyl) ethylene) on male offspring of Wistar rats.","14718175","Dichlorodiphenyl Dichloroethylene","Prostate",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Prostate",0,1,"9882589",1999,"Interactive effects of TCDD and p,p'-DDE on male reproductive tract development in in utero and lactationally exposed rats.","9882589","Dichlorodiphenyl Dichloroethylene","Prostate",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Seminiferous Tubules",1,1,"16918713",2006,"Effects of perinatal combined exposure to 1,1-dichloro-2,2 bis (p-chlorophenyl) ethylene and tributyltin on male reproductive system.","16918713","Dichlorodiphenyl Dichloroethylene","Seminiferous Tubules",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,"11675272",2001,"Antiandrogenic pesticides disrupt sexual characteristics in the adult male guppy Poecilia reticulata.","11675272","Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,"11882472",2002,"Environmental organochlorines and semen quality: results of a pilot study.","11882472","Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,"12948891",2003,"The relationship between human semen parameters and environmental exposure to polychlorinated biphenyls and p,p'-DDE.","12948891","Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Count",0,1,"15907656",2005,"Comparative study of dichlorodiphenyldichloroethylene in blood and semen of two young male populations: lack of relationship to infertility, but evidence of high exposure of the mothers.","15907656","Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,"16399166",2006,"p,p'-DDE fails to reduce the competitive reproductive fitness in Nigerian male guppies.","16399166","Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,"16755259",2006,"Semen quality and exposure to persistent organochlorine pollutants.","16755259","Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,"16918713",2006,"Effects of perinatal combined exposure to 1,1-dichloro-2,2 bis (p-chlorophenyl) ethylene and tributyltin on male reproductive system.","16918713","Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Count",0,1,"21736938",2011,"Differences in serum levels of CB-153 and p,p'-DDE, and reproductive parameters between men living south and north in Norway.","21736938","Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Count",0,1,"9882589",1999,"Interactive effects of TCDD and p,p'-DDE on male reproductive tract development in in utero and lactationally exposed rats.","9882589","Dichlorodiphenyl Dichloroethylene","Sperm Count",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,"11882472",2002,"Environmental organochlorines and semen quality: results of a pilot study.","11882472","Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,"12948891",2003,"The relationship between human semen parameters and environmental exposure to polychlorinated biphenyls and p,p'-DDE.","12948891","Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,"15284211",2004,"Exposure to CB-153 and p,p'-DDE and male reproductive function.","15284211","Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Motility",0,1,"15907656",2005,"Comparative study of dichlorodiphenyldichloroethylene in blood and semen of two young male populations: lack of relationship to infertility, but evidence of high exposure of the mothers.","15907656","Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,"16755259",2006,"Semen quality and exposure to persistent organochlorine pollutants.","16755259","Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,"16918713",2006,"Effects of perinatal combined exposure to 1,1-dichloro-2,2 bis (p-chlorophenyl) ethylene and tributyltin on male reproductive system.","16918713","Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,"17008049",2006,"Association between exposure to persistent organohalogen pollutants and epididymal and accessory sex gland function: multicentre study in Inuit and European populations.","17008049","Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Sperm Motility",0,1,"21736938",2011,"Differences in serum levels of CB-153 and p,p'-DDE, and reproductive parameters between men living south and north in Norway.","21736938","Dichlorodiphenyl Dichloroethylene","Sperm Motility",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatogenesis",1,1,"20025943",2010,"p,p'-DDE induces testicular apoptosis in prepubertal rats via the Fas/FasL pathway.","20025943","Dichlorodiphenyl Dichloroethylene","Spermatogenesis",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,"11882472",2002,"Environmental organochlorines and semen quality: results of a pilot study.","11882472","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,"12948891",2003,"The relationship between human semen parameters and environmental exposure to polychlorinated biphenyls and p,p'-DDE.","12948891","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",0,1,"14645167",2003,"Lack of an association between environmental exposure to polychlorinated biphenyls and p,p'-DDE and DNA damage in human sperm measured using the neutral comet assay.","14645167","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,"15687046",2005,"Exposure to PCBs and p,p'-DDE and human sperm chromatin integrity.","15687046","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",0,1,"15907656",2005,"Comparative study of dichlorodiphenyldichloroethylene in blood and semen of two young male populations: lack of relationship to infertility, but evidence of high exposure of the mothers.","15907656","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,"16223788",2005,"Exposure to PCB and p, p'-DDE in European and Inuit populations: impact on human sperm chromatin integrity.","16223788","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,"16675426",2006,"Impact of PCB and p,p'-DDE contaminants on human sperm Y:X chromosome ratio: studies in three European populations and the Inuit population in Greenland.","16675426","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,"16755259",2006,"Semen quality and exposure to persistent organochlorine pollutants.","16755259","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,"16918713",2006,"Effects of perinatal combined exposure to 1,1-dichloro-2,2 bis (p-chlorophenyl) ethylene and tributyltin on male reproductive system.","16918713","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,"22189045",2012,"Environmental exposure to polychlorinated biphenyls and p,p'-DDE and sperm sex-chromosome disomy.","22189045","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,"24067601",2013,"p,p'-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations.","24067601","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,"3090950",1986,"Polychlorobiphenyl congeners, p,p'-DDE, and sperm function in humans.","3090950","Dichlorodiphenyl Dichloroethylene","Spermatozoa",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Testicular Neoplasms",1,1,"18445826",2008,"Persistent organochlorine pesticides and risk of testicular germ cell tumors.","18445826","Dichlorodiphenyl Dichloroethylene","Testicular Neoplasms",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Testis",1,1,"11460698",2000,"Intersexes in Mississippi River shovelnose sturgeon sampled below Saint Louis, Missouri, USA.","11460698","Dichlorodiphenyl Dichloroethylene","Testis",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Testis",1,1,"16399166",2006,"p,p'-DDE fails to reduce the competitive reproductive fitness in Nigerian male guppies.","16399166","Dichlorodiphenyl Dichloroethylene","Testis",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Testis",1,1,"19490997",2009,"Effects of maternal exposure to di-isononylphthalate (DINP) and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE) on steroidogenesis in the fetal rat testis and adrenal gland.","19490997","Dichlorodiphenyl Dichloroethylene","Testis",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Testis",1,1,"20025943",2010,"p,p'-DDE induces testicular apoptosis in prepubertal rats via the Fas/FasL pathway.","20025943","Dichlorodiphenyl Dichloroethylene","Testis",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Testis",0,1,"22841741",2012,"Reproductive hormone profile and pubertal development in 14-year-old boys prenatally exposed to polychlorinated biphenyls.","22841741","Dichlorodiphenyl Dichloroethylene","Testis",1,1,1]
["Dichlorodiphenyl Dichloroethylene","Urogenital Abnormalities",1,1,"17272288",2007,"In utero exposure to the antiandrogen 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) in relation to anogenital distance in male newborns from Chiapas, México.","17272288","Dichlorodiphenyl Dichloroethylene","Urogenital Abnormalities",1,1,1]
["dicyclohexyl phthalate","Epididymis",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","dicyclohexyl phthalate","Epididymis",1,1,1]
["dicyclohexyl phthalate","Prostate",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","dicyclohexyl phthalate","Prostate",1,1,1]
["dicyclohexyl phthalate","Sertoli Cells",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","dicyclohexyl phthalate","Sertoli Cells",1,1,1]
["dicyclohexyl phthalate","Sperm Count",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","dicyclohexyl phthalate","Sperm Count",1,1,1]
["dicyclohexyl phthalate","Sperm Head",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","dicyclohexyl phthalate","Sperm Head",1,1,1]
["dicyclohexyl phthalate","Testis",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","dicyclohexyl phthalate","Testis",1,1,1]
["dicyclohexyl phthalate","Testis",1,1,"23836838",2014,"In utero exposure to dicyclohexyl and di-n-hexyl phthalate possess genotoxic effects on testicular cells of male rats after birth in the comet and TUNEL assays.","23836838","dicyclohexyl phthalate","Testis",1,1,1]
["diethyl phthalate","Prostate",1,1,"9114307",1997,"Reproductive toxicology. Diethylphthalate.","9114307","diethyl phthalate","Prostate",1,1,1]
["diethyl phthalate","Sperm Count",1,1,"9114307",1997,"Reproductive toxicology. Diethylphthalate.","9114307","diethyl phthalate","Sperm Count",1,1,1]
["diethyl phthalate","Testis",1,1,"18411233",2008,"A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner.","18411233","diethyl phthalate","Testis",1,1,1]
["Diethylhexyl Phthalate","Acrosome",1,1,"17543380",2007,"Early pre-pubertal exposure to low-dose oral di(2-ethylhexyl) phthalate does not affect sperm plasma membrane stability, acrosomal integrity or chromatin structure in the post-pubertal boar.","17543380","Diethylhexyl Phthalate","Acrosome",1,null,1]
["Diethylhexyl Phthalate","Blood-Testis Barrier",1,1,"23892333",2013,"Effects on the local immunity in the testis by exposure to di-(2-ethylhexyl) phthalate (DEHP) in mice.","23892333","Diethylhexyl Phthalate","Blood-Testis Barrier",1,null,1]
["Diethylhexyl Phthalate","Cryptorchidism",0,1,"21752447",2011,"In vitro effects of estradiol-17?, monobutyl phthalate and mono-(2-ethylhexyl) phthalate on the secretion of testosterone and insulin-like peptide 3 by interstitial cells of scrotal and retained testes in dogs.","21752447","Diethylhexyl Phthalate","Cryptorchidism",1,null,1]
["Diethylhexyl Phthalate","Epididymis",1,1,"16303285",2006,"Testicular toxicity of DEHP, but not DEHA, is elevated under conditions of thioacetamide-induced liver damage.","16303285","Diethylhexyl Phthalate","Epididymis",1,null,1]
["Diethylhexyl Phthalate","Epididymis",1,1,"16952438",2006,"Toxicity of di(2-ethylhexyl)phthalate (DEHP) and di(2-ethylhexyl)adipate (DEHA) under conditions of renal dysfunction induced with folic acid in rats: enhancement of male reproductive toxicity of DEHP is associated with an increase of the mono-derivative.","16952438","Diethylhexyl Phthalate","Epididymis",1,null,1]
["Diethylhexyl Phthalate","Epididymis",1,1,"17462840",2007,"Differential expression of the phthalate syndrome in male Sprague-Dawley and Wistar rats after in utero DEHP exposure.","17462840","Diethylhexyl Phthalate","Epididymis",1,null,1]
["Diethylhexyl Phthalate","Epididymis",1,1,"21714771",2011,"Reproductive toxicity of di(2-ethylhexyl) phthalate in selenium-supplemented and selenium-deficient rats.","21714771","Diethylhexyl Phthalate","Epididymis",1,null,1]
["Diethylhexyl Phthalate","Epididymis",1,1,"22462442",2012,"Two generation reproductive and developmental toxicity following subchronic exposure of pubescent male mice to di(2-ethylhexyl)phthalate.","22462442","Diethylhexyl Phthalate","Epididymis",1,null,1]
["Diethylhexyl Phthalate","Epididymis",1,1,"3709461",1986,"Effects of di(2-ethylhexyl) phthalate on the gonadal pathophysiology, sperm morphology, and reproductive performance of male rats.","3709461","Diethylhexyl Phthalate","Epididymis",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"11099646",2000,"The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat.","11099646","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",0,1,"11333183",2001,"Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer Di(2-ethylhexyl) phthalate.","11333183","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1028,I1028)","v":"Diethylhexyl Phthalate"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1028,J1028)","v":"Genitalia, Male"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1028,H1028)","v":"12642148"},2003,"Di(2-ethylhexyl) adipate (DEHA) induced developmental toxicity but not antiandrogenic effects in pre- and postnatally exposed Wistar rats.","12642148","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"14687758",2004,"Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis.","14687758","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"15336709",2004,"Plasticizers, infant nutrition and reproductive health.","15336709","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"15749265",2005,"Antiandrogenic effects in male rats perinatally exposed to a mixture of di(2-ethylhexyl) phthalate and di(2-ethylhexyl) adipate.","15749265","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"16239449",2005,"Toxicology. Panel finds no proof that phthalates harm infant reproductive systems.","16239449","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"16866186",2006,"Phthalate affect the reproductive function and sexual behavior of male Wistar rats.","16866186","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"16952438",2006,"Toxicity of di(2-ethylhexyl)phthalate (DEHP) and di(2-ethylhexyl)adipate (DEHA) under conditions of renal dysfunction induced with folic acid in rats: enhancement of male reproductive toxicity of DEHP is associated with an increase of the mono-derivative.","16952438","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"16996189",2006,"A dose response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult male offspring rats.","16996189","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"17085928",2006,"Effects of in utero and lactational exposure to di(2-ethylhexyl)phthalate on somatic and physical development in rat offspring.","17085928","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"17400582",2007,"Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes.","17400582","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"19096195",2009,"Di-(2-ethylhexyl) phthalate upregulates ATF3 expression and suppresses apoptosis in mouse genital tubercle.","19096195","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"19482887",2009,"Transgenerational effects of Di (2-ethylhexyl) phthalate in the male CRL:CD(SD) rat: added value of assessing multiple offspring per litter.","19482887","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"23041310",2012,"Non-monotonic dose effects of in utero exposure to di(2-ethylhexyl) phthalate (DEHP) on testicular and serum testosterone and anogenital distance in male mouse fetuses.","23041310","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Genitalia, Male",1,1,"23959011",2013,"Disruption of reproductive development in male rat offspring following gestational and lactational exposure to di-(2-ethylhexyl) phthalate and genistein.","23959011","Diethylhexyl Phthalate","Genitalia, Male",1,null,1]
["Diethylhexyl Phthalate","Gonadal Dysgenesis",1,1,"17258888",2007,"Phthalate ester toxicity in Leydig cells: developmental timing and dosage considerations.","17258888","Diethylhexyl Phthalate","Gonadal Dysgenesis",1,null,1]
["Diethylhexyl Phthalate","Gonadal Dysgenesis",1,1,"19912166",2010,"Dynamic epigenetic changes involved in testicular toxicity induced by di-2-(ethylhexyl) phthalate in mice.","19912166","Diethylhexyl Phthalate","Gonadal Dysgenesis",1,null,1]
["Diethylhexyl Phthalate","Hypospadias",1,1,"18686198",2008,"Di(2-ethylhexyl) phthalate (DEHP) increases transforming growth factor-beta1 expression in fetal mouse genital tubercles.","18686198","Diethylhexyl Phthalate","Hypospadias",1,null,1]
["Diethylhexyl Phthalate","Hypospadias",1,1,"19096195",2009,"Di-(2-ethylhexyl) phthalate upregulates ATF3 expression and suppresses apoptosis in mouse genital tubercle.","19096195","Diethylhexyl Phthalate","Hypospadias",1,null,1]
["Diethylhexyl Phthalate","Hypospadias",1,1,"23228707",2013,"Dose-related effect by maternal exposure to di-(2-ethylhexyl) phthalate plasticizer on inducing hypospadiac male rats.","23228707","Diethylhexyl Phthalate","Hypospadias",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"11099646",2000,"The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat.","11099646","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",0,1,"11566751",2001,"Modulation of rat Leydig cell steroidogenic function by di(2-ethylhexyl)phthalate.","11566751","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"15749266",2005,"Early testicular effects in rats perinatally exposed to DEHP in combination with DEHA--apoptosis assessment and immunohistochemical studies.","15749266","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"16979278",2006,"Effect of in utero exposure to di-(2-ethylhexyl)phthalate: distribution in the rat fetus and testosterone production by rat fetal testis in culture.","16979278","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",0,1,"17009524",2006,"[Di(2-ethylhexyl) phthalate affects the testes and leydig cells of neonatal KM mice].","17009524","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"17258888",2007,"Phthalate ester toxicity in Leydig cells: developmental timing and dosage considerations.","17258888","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"18322279",2008,"In utero exposure to di-(2-ethylhexyl) phthalate exerts both short-term and long-lasting suppressive effects on testosterone production in the rat.","18322279","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"18469139",2008,"Involvement of testicular growth factors in fetal Leydig cell aggregation after exposure to phthalate in utero.","18469139","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"18534133",2008,"Effects of diethylhexyl phthalate (DEHP) on INSL3 mRNA expression by Leydig cells derived from mouse embryos and in newborn mice.","18534133","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"19144960",2009,"In utero and lactational exposures to diethylhexyl-phthalate affect two populations of Leydig cells in male Long-Evans rats.","19144960","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",0,1,"19452688",2009,"[Effects of Di (2-ethylhexyl) phthalate on the testis and testicular gubernaculum of fetal KM mice].","19452688","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"19819939",2009,"In utero exposure to di-(2-ethylhexyl) phthalate decreases mineralocorticoid receptor expression in the adult testis.","19819939","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"21389346",2011,"In utero exposure to the antiandrogen di-(2-ethylhexyl) phthalate decreases adrenal aldosterone production in the adult rat.","21389346","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",0,1,"21752447",2011,"In vitro effects of estradiol-17?, monobutyl phthalate and mono-(2-ethylhexyl) phthalate on the secretion of testosterone and insulin-like peptide 3 by interstitial cells of scrotal and retained testes in dogs.","21752447","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"22402212",2012,"Human testis steroidogenesis is inhibited by phthalates.","22402212","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Leydig Cells",1,1,"23391632",2013,"The increased number of Leydig cells by di(2-ethylhexyl) phthalate comes from the differentiation of stem cells into Leydig cell lineage in the adult rat testis.","23391632","Diethylhexyl Phthalate","Leydig Cells",1,null,1]
["Diethylhexyl Phthalate","Prostate",1,1,"16952438",2006,"Toxicity of di(2-ethylhexyl)phthalate (DEHP) and di(2-ethylhexyl)adipate (DEHA) under conditions of renal dysfunction induced with folic acid in rats: enhancement of male reproductive toxicity of DEHP is associated with an increase of the mono-derivative.","16952438","Diethylhexyl Phthalate","Prostate",1,null,1]
["Diethylhexyl Phthalate","Prostate",1,1,"20420898",2010,"Low-dose perinatal exposure to di(2-ethylhexyl) phthalate induces anti-androgenic effects in male rats.","20420898","Diethylhexyl Phthalate","Prostate",1,null,1]
["Diethylhexyl Phthalate","Prostate",0,1,"3716815",1986,"Effects of di-(2-ethylhexyl) phthalate and five of its metabolites on rat testis in vivo and in in vitro.","3716815","Diethylhexyl Phthalate","Prostate",1,null,1]
["Diethylhexyl Phthalate","Seminal Vesicles",1,1,"16952438",2006,"Toxicity of di(2-ethylhexyl)phthalate (DEHP) and di(2-ethylhexyl)adipate (DEHA) under conditions of renal dysfunction induced with folic acid in rats: enhancement of male reproductive toxicity of DEHP is associated with an increase of the mono-derivative.","16952438","Diethylhexyl Phthalate","Seminal Vesicles",1,null,1]
["Diethylhexyl Phthalate","Seminiferous Epithelium",1,1,"23892333",2013,"Effects on the local immunity in the testis by exposure to di-(2-ethylhexyl) phthalate (DEHP) in mice.","23892333","Diethylhexyl Phthalate","Seminiferous Epithelium",1,null,1]
["Diethylhexyl Phthalate","Seminiferous Tubules",0,1,"12749820",2003,"The effects of mono-2-ethylhexyl phathalate, adriamycin and N-ethyl-N-nitrosourea on stage-specific apoptosis and DNA synthesis in the mouse spermatogenesis.","12749820","Diethylhexyl Phthalate","Seminiferous Tubules",1,null,1]
["Diethylhexyl Phthalate","Seminiferous Tubules",1,1,"12851149",2003,"Evaluation of reproductive development following intravenous and oral exposure to DEHP in male neonatal rats.","12851149","Diethylhexyl Phthalate","Seminiferous Tubules",1,null,1]
["Diethylhexyl Phthalate","Seminiferous Tubules",1,1,"16141652",2005,"Influence of di-(2-ethylhexyl)phthalate on fetal testicular development by oral administration to pregnant rats.","16141652","Diethylhexyl Phthalate","Seminiferous Tubules",1,null,1]
["Diethylhexyl Phthalate","Seminiferous Tubules",1,1,"16678996",2006,"Effect of di-(2-ethylhexyl) phthalate on N-cadherin and catenin protein expression in rat testis.","16678996","Diethylhexyl Phthalate","Seminiferous Tubules",1,null,1]
["Diethylhexyl Phthalate","Seminiferous Tubules",1,1,"23536373",2013,"Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice.","23536373","Diethylhexyl Phthalate","Seminiferous Tubules",1,null,1]
["Diethylhexyl Phthalate","Seminiferous Tubules",1,1,"8540215",1995,"Testicular toxicity of Di(2-ethylhexyl)phthalate in developing rats.","8540215","Diethylhexyl Phthalate","Seminiferous Tubules",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",1,1,"10544061",1999,"Participation of the Fas-signaling system in the initiation of germ cell apoptosis in young rat testes after exposure to mono-(2-ethylhexyl) phthalate.","10544061","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",1,1,"10906286",2000,"A single dose of Di-(2-ethylhexyl) phthalate in neonatal rats alters gonocytes, reduces sertoli cell proliferation, and decreases cyclin D2 expression.","10906286","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",0,1,"12595153",2003,"Fas- or FasL-deficient mice display an increased sensitivity to nitrobenzene-induced testicular germ cell apoptosis.","12595153","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",0,1,"15134331",2004,"Effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in rats in vitro.","15134331","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",1,1,"15365238",2004,"An ultrastructural study on cytotoxic effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in Shiba goat in vitro.","15365238","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",0,1,"15371270",2005,"The p53 protein influences the sensitivity of testicular germ cells to mono-(2-ethylhexyl) phthalate-induced apoptosis by increasing the membrane levels of Fas and DR5 and decreasing the intracellular amount of c-FLIP.","15371270","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",1,1,"15749266",2005,"Early testicular effects in rats perinatally exposed to DEHP in combination with DEHA--apoptosis assessment and immunohistochemical studies.","15749266","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",1,1,"15907966",2005,"Mono-(2-ethylhexyl) phthalate (MEHP) induces testicular alterations in male guinea pigs at prepubertal stage.","15907966","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",1,1,"16678996",2006,"Effect of di-(2-ethylhexyl) phthalate on N-cadherin and catenin protein expression in rat testis.","16678996","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",0,1,"17380854",2007,"An ultrastructural study on the effects of mono(2-ethylhexyl) phthalate on mice testes: cell death and sloughing of spermatogenic cells.","17380854","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",0,1,"19038859",2009,"TNF alpha-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents is partially regulated by MMP2.","19038859","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",0,1,"19452688",2009,"[Effects of Di (2-ethylhexyl) phthalate on the testis and testicular gubernaculum of fetal KM mice].","19452688","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",1,1,"20100735",2010,"FasL gene-deficient mice display a limited disruption in spermatogenesis and inhibition of mono-(2-ethylhexyl) phthalate-induced germ cell apoptosis.","20100735","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",1,1,"21868750",2012,"Inhibition of claudin-11 and occludin expression in rat Sertoli cells by mono-(2-ethylhexyl) phthalate through p44/42 mitogen-activated protein kinase pathway.","21868750","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",1,1,"22402212",2012,"Human testis steroidogenesis is inhibited by phthalates.","22402212","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sertoli Cells",1,1,"8607140",1996,"Mono-(2-ethylhexyl) phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes.","8607140","Diethylhexyl Phthalate","Sertoli Cells",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"12642148",2003,"Di(2-ethylhexyl) adipate (DEHA) induced developmental toxicity but not antiandrogenic effects in pre- and postnatally exposed Wistar rats.","12642148","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"1363164",1992,"The influence of low protein diet on the testicular toxicity of di(2-ethylhexyl)phthalate.","1363164","Diethylhexyl Phthalate","Sperm Count",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1092,I1092)","v":"Diethylhexyl Phthalate"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1092,J1092)","v":"Sperm Count"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1092,H1092)","v":"15749265"},2005,"Antiandrogenic effects in male rats perinatally exposed to a mixture of di(2-ethylhexyl) phthalate and di(2-ethylhexyl) adipate.","15749265","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"1581667",1992,"Effect of di(2-ethylhexyl)phthalate administration on rat sperm count and on sperm metabolic enzymes.","1581667","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"16141652",2005,"Influence of di-(2-ethylhexyl)phthalate on fetal testicular development by oral administration to pregnant rats.","16141652","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"16637905",2006,"Does exposure to di(2-ethylhexyl) phthalate in pre-pubertal boars affect semen quality post-puberty?","16637905","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"16996189",2006,"A dose response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult male offspring rats.","16996189","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"19482887",2009,"Transgenerational effects of Di (2-ethylhexyl) phthalate in the male CRL:CD(SD) rat: added value of assessing multiple offspring per litter.","19482887","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"21714771",2011,"Reproductive toxicity of di(2-ethylhexyl) phthalate in selenium-supplemented and selenium-deficient rats.","21714771","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"22462442",2012,"Two generation reproductive and developmental toxicity following subchronic exposure of pubescent male mice to di(2-ethylhexyl)phthalate.","22462442","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"22828881",2011,"Effects of perinatal exposure to bisphenol A and di(2-ethylhexyl)-phthalate on gonadal development of male mice.","22828881","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"23536373",2013,"Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice.","23536373","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"3709450",1986,"Genetic toxicology of phthalate esters: mutagenic and other genotoxic effects.","3709450","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Count",1,1,"3709461",1986,"Effects of di(2-ethylhexyl) phthalate on the gonadal pathophysiology, sperm morphology, and reproductive performance of male rats.","3709461","Diethylhexyl Phthalate","Sperm Count",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"12642148",2003,"Di(2-ethylhexyl) adipate (DEHA) induced developmental toxicity but not antiandrogenic effects in pre- and postnatally exposed Wistar rats.","12642148","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"12851149",2003,"Evaluation of reproductive development following intravenous and oral exposure to DEHP in male neonatal rats.","12851149","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"15749265",2005,"Antiandrogenic effects in male rats perinatally exposed to a mixture of di(2-ethylhexyl) phthalate and di(2-ethylhexyl) adipate.","15749265","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"16141652",2005,"Influence of di-(2-ethylhexyl)phthalate on fetal testicular development by oral administration to pregnant rats.","16141652","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"16637905",2006,"Does exposure to di(2-ethylhexyl) phthalate in pre-pubertal boars affect semen quality post-puberty?","16637905","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"16961572",2006,"Effects of exposure of pre-pubertal boars to di(2-ethylhexyl) phthalate on their frozen-thawed sperm viability post-puberty.","16961572","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"19733116",2009,"Urinary di(2-ethylhexyl)phthalate (DEHP)--metabolites and male human markers of reproductive function.","19733116","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"20551087",2011,"Environmental and experimental exposure of phthalate esters: the toxicological consequence on human sperm.","20551087","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"21714771",2011,"Reproductive toxicity of di(2-ethylhexyl) phthalate in selenium-supplemented and selenium-deficient rats.","21714771","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",0,1,"23226291",2012,"The effects of Di-(2-ethylhexyl)-phthalate exposure on fertilization and embryonic development in vitro and testicular genomic mutation in vivo.","23226291","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"23536373",2013,"Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice.","23536373","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Sperm Motility",1,1,"3709461",1986,"Effects of di(2-ethylhexyl) phthalate on the gonadal pathophysiology, sperm morphology, and reproductive performance of male rats.","3709461","Diethylhexyl Phthalate","Sperm Motility",1,null,1]
["Diethylhexyl Phthalate","Spermatocytes",1,1,"12490136",2002,"Death receptor response in rodent testis after mono-(2-ethylhexyl) phthalate exposure.","12490136","Diethylhexyl Phthalate","Spermatocytes",1,null,1]
["Diethylhexyl Phthalate","Spermatocytes",1,1,"15764490",2004,"Mono-(2-ethylhexyl) phthalate (MEHP) induces spermatogenic cell apoptosis in guinea pig testes at prepubertal stage in vitro.","15764490","Diethylhexyl Phthalate","Spermatocytes",1,null,1]
["Diethylhexyl Phthalate","Spermatocytes",1,1,"16678996",2006,"Effect of di-(2-ethylhexyl) phthalate on N-cadherin and catenin protein expression in rat testis.","16678996","Diethylhexyl Phthalate","Spermatocytes",1,null,1]
["Diethylhexyl Phthalate","Spermatocytes",1,1,"18077825",2008,"Mono-(2-ethylhexyl) phthalate increases spermatocyte mitochondrial peroxiredoxin 3 and cyclooxygenase 2.","18077825","Diethylhexyl Phthalate","Spermatocytes",1,null,1]
["Diethylhexyl Phthalate","Spermatocytes",0,1,"3716815",1986,"Effects of di-(2-ethylhexyl) phthalate and five of its metabolites on rat testis in vivo and in in vitro.","3716815","Diethylhexyl Phthalate","Spermatocytes",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"11694130",2001,"From the Food and Drug Administration.","11694130","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"11836017",2002,"Testicular toxicity of di-(2-ethylhexyl)phthalate in young Sprague-Dawley rats.","11836017","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",0,1,"12749820",2003,"The effects of mono-2-ethylhexyl phathalate, adriamycin and N-ethyl-N-nitrosourea on stage-specific apoptosis and DNA synthesis in the mouse spermatogenesis.","12749820","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",0,1,"15379967",2004,"Di-(2-ethylhexyl) phthalate induces severe aspermatogenesis in mice, however, subsequent antioxidant vitamins supplementation accelerates regeneration of the seminiferous epithelium.","15379967","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"16303285",2006,"Testicular toxicity of DEHP, but not DEHA, is elevated under conditions of thioacetamide-induced liver damage.","16303285","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"16678996",2006,"Effect of di-(2-ethylhexyl) phthalate on N-cadherin and catenin protein expression in rat testis.","16678996","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",0,1,"16855774",2007,"Short-term effects of di-(2-ethylhexyl) phthalate on testes, liver, kidneys and pancreas in mice.","16855774","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"16952438",2006,"Toxicity of di(2-ethylhexyl)phthalate (DEHP) and di(2-ethylhexyl)adipate (DEHA) under conditions of renal dysfunction induced with folic acid in rats: enhancement of male reproductive toxicity of DEHP is associated with an increase of the mono-derivative.","16952438","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",0,1,"17380854",2007,"An ultrastructural study on the effects of mono(2-ethylhexyl) phthalate on mice testes: cell death and sloughing of spermatogenic cells.","17380854","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",0,1,"19038859",2009,"TNF alpha-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents is partially regulated by MMP2.","19038859","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"20100735",2010,"FasL gene-deficient mice display a limited disruption in spermatogenesis and inhibition of mono-(2-ethylhexyl) phthalate-induced germ cell apoptosis.","20100735","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"20561692",2010,"Mechanisms of toxicity of di(2-ethylhexyl) phthalate on the reproductive health of male zebrafish.","20561692","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"21515331",2011,"Induction of ROS, p53, p21 in DEHP- and MEHP-exposed LNCaP cells-protection by selenium compounds.","21515331","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"21868750",2012,"Inhibition of claudin-11 and occludin expression in rat Sertoli cells by mono-(2-ethylhexyl) phthalate through p44/42 mitogen-activated protein kinase pathway.","21868750","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"23536373",2013,"Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice.","23536373","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"23892333",2013,"Effects on the local immunity in the testis by exposure to di-(2-ethylhexyl) phthalate (DEHP) in mice.","23892333","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"24011190",2013,"Bis-(2-ethylexhyl) phthalate impairs spermatogenesis in zebrafish (Danio rerio).","24011190","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",0,1,"24057186",2013,"Effects of diethylhexyl phthalate (DEHP) given neonatally on spermatogenesis of mice.","24057186","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",0,1,"2879365",1986,"Effect of di(2-ethylhexyl)phthalate (DEHP) on spermatogenesis in adult rats.","2879365","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"2881530",1986,"Testicular atrophy induced by di(2-ethylhexyl)phthalate: changes in histology, cell specific enzyme activities and zinc concentrations in rat testis.","2881530","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"3709461",1986,"Effects of di(2-ethylhexyl) phthalate on the gonadal pathophysiology, sperm morphology, and reproductive performance of male rats.","3709461","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"3967638",1985,"Reversibility of testicular atrophy induced by Di(2-ethylhexyl) phthalate in rats.","3967638","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"4068057",1985,"Antifertility and mutagenic effects in mice from parenteral administration of di-2-ethylhexyl phthalate (DEHP).","4068057","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogenesis",1,1,"8540215",1995,"Testicular toxicity of Di(2-ethylhexyl)phthalate in developing rats.","8540215","Diethylhexyl Phthalate","Spermatogenesis",1,null,1]
["Diethylhexyl Phthalate","Spermatogonia",1,1,"15907966",2005,"Mono-(2-ethylhexyl) phthalate (MEHP) induces testicular alterations in male guinea pigs at prepubertal stage.","15907966","Diethylhexyl Phthalate","Spermatogonia",1,null,1]
["Diethylhexyl Phthalate","Spermatogonia",1,1,"16678996",2006,"Effect of di-(2-ethylhexyl) phthalate on N-cadherin and catenin protein expression in rat testis.","16678996","Diethylhexyl Phthalate","Spermatogonia",1,null,1]
["Diethylhexyl Phthalate","Spermatogonia",1,1,"22564763",2012,"Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia.","22564763","Diethylhexyl Phthalate","Spermatogonia",1,null,1]
["Diethylhexyl Phthalate","Spermatogonia",1,1,"23536373",2013,"Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice.","23536373","Diethylhexyl Phthalate","Spermatogonia",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"10544061",1999,"Participation of the Fas-signaling system in the initiation of germ cell apoptosis in young rat testes after exposure to mono-(2-ethylhexyl) phthalate.","10544061","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"10650961",2000,"Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand.","10650961","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"10906286",2000,"A single dose of Di-(2-ethylhexyl) phthalate in neonatal rats alters gonocytes, reduces sertoli cell proliferation, and decreases cyclin D2 expression.","10906286","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",0,1,"12595153",2003,"Fas- or FasL-deficient mice display an increased sensitivity to nitrobenzene-induced testicular germ cell apoptosis.","12595153","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"12642148",2003,"Di(2-ethylhexyl) adipate (DEHA) induced developmental toxicity but not antiandrogenic effects in pre- and postnatally exposed Wistar rats.","12642148","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",0,1,"12749820",2003,"The effects of mono-2-ethylhexyl phathalate, adriamycin and N-ethyl-N-nitrosourea on stage-specific apoptosis and DNA synthesis in the mouse spermatogenesis.","12749820","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"12851149",2003,"Evaluation of reproductive development following intravenous and oral exposure to DEHP in male neonatal rats.","12851149","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1156,I1156)","v":"Diethylhexyl Phthalate"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1156,J1156)","v":"Spermatozoa"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1156,H1156)","v":"1363164"},1992,"The influence of low protein diet on the testicular toxicity of di(2-ethylhexyl)phthalate.","1363164","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",0,1,"15134331",2004,"Effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in rats in vitro.","15134331","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"15365238",2004,"An ultrastructural study on cytotoxic effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in Shiba goat in vitro.","15365238","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",0,1,"15371270",2005,"The p53 protein influences the sensitivity of testicular germ cells to mono-(2-ethylhexyl) phthalate-induced apoptosis by increasing the membrane levels of Fas and DR5 and decreasing the intracellular amount of c-FLIP.","15371270","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"1581667",1992,"Effect of di(2-ethylhexyl)phthalate administration on rat sperm count and on sperm metabolic enzymes.","1581667","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"16637905",2006,"Does exposure to di(2-ethylhexyl) phthalate in pre-pubertal boars affect semen quality post-puberty?","16637905","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"16809437",2006,"Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages.","16809437","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"16961572",2006,"Effects of exposure of pre-pubertal boars to di(2-ethylhexyl) phthalate on their frozen-thawed sperm viability post-puberty.","16961572","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"16996189",2006,"A dose response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult male offspring rats.","16996189","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",0,1,"17090632",2007,"DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolites.","17090632","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"17543380",2007,"Early pre-pubertal exposure to low-dose oral di(2-ethylhexyl) phthalate does not affect sperm plasma membrane stability, acrosomal integrity or chromatin structure in the post-pubertal boar.","17543380","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"18755736",2008,"Cross-talk between the Akt and NF-kappaB signaling pathways inhibits MEHP-induced germ cell apoptosis.","18755736","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"19240039",2009,"Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis.","19240039","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"19733116",2009,"Urinary di(2-ethylhexyl)phthalate (DEHP)--metabolites and male human markers of reproductive function.","19733116","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"20100735",2010,"FasL gene-deficient mice display a limited disruption in spermatogenesis and inhibition of mono-(2-ethylhexyl) phthalate-induced germ cell apoptosis.","20100735","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"20551087",2011,"Environmental and experimental exposure of phthalate esters: the toxicological consequence on human sperm.","20551087","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"20561692",2010,"Mechanisms of toxicity of di(2-ethylhexyl) phthalate on the reproductive health of male zebrafish.","20561692","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"21714771",2011,"Reproductive toxicity of di(2-ethylhexyl) phthalate in selenium-supplemented and selenium-deficient rats.","21714771","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"22118310",2011,"Food safety involving ingestion of foods and beverages prepared with phthalate-plasticizer-containing clouding agents.","22118310","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"22402212",2012,"Human testis steroidogenesis is inhibited by phthalates.","22402212","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"22462442",2012,"Two generation reproductive and developmental toxicity following subchronic exposure of pubescent male mice to di(2-ethylhexyl)phthalate.","22462442","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"23118965",2012,"Cellular and molecular effect of MEHP Involving LXR? in human fetal testis and ovary.","23118965","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",0,1,"23226291",2012,"The effects of Di-(2-ethylhexyl)-phthalate exposure on fertilization and embryonic development in vitro and testicular genomic mutation in vivo.","23226291","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"23268404",2012,"[Effect of di-(2-ethylhexyl)phthalate and its metabolite mono(2-ethylhexyl)phthalate on  spermatogenic cell apoptosis in young male Wistar rats].","23268404","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"23536373",2013,"Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice.","23536373","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"3709450",1986,"Genetic toxicology of phthalate esters: mutagenic and other genotoxic effects.","3709450","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"3709461",1986,"Effects of di(2-ethylhexyl) phthalate on the gonadal pathophysiology, sperm morphology, and reproductive performance of male rats.","3709461","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Spermatozoa",1,1,"8607140",1996,"Mono-(2-ethylhexyl) phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes.","8607140","Diethylhexyl Phthalate","Spermatozoa",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"10650961",2000,"Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand.","10650961","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"11099646",2000,"The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat.","11099646","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"11566751",2001,"Modulation of rat Leydig cell steroidogenic function by di(2-ethylhexyl)phthalate.","11566751","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"11694130",2001,"From the Food and Drug Administration.","11694130","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"11762309",2001,"New risk for newborns.","11762309","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"11836017",2002,"Testicular toxicity of di-(2-ethylhexyl)phthalate in young Sprague-Dawley rats.","11836017","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"12490136",2002,"Death receptor response in rodent testis after mono-(2-ethylhexyl) phthalate exposure.","12490136","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"12498735",2002,"Gene expression changes induced in mouse liver by di(2-ethylhexyl) phthalate.","12498735","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"12595153",2003,"Fas- or FasL-deficient mice display an increased sensitivity to nitrobenzene-induced testicular germ cell apoptosis.","12595153","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"12851149",2003,"Evaluation of reproductive development following intravenous and oral exposure to DEHP in male neonatal rats.","12851149","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"1363164",1992,"The influence of low protein diet on the testicular toxicity of di(2-ethylhexyl)phthalate.","1363164","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"14687758",2004,"Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis.","14687758","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"15134331",2004,"Effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in rats in vitro.","15134331","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"15365238",2004,"An ultrastructural study on cytotoxic effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in Shiba goat in vitro.","15365238","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"15371270",2005,"The p53 protein influences the sensitivity of testicular germ cells to mono-(2-ethylhexyl) phthalate-induced apoptosis by increasing the membrane levels of Fas and DR5 and decreasing the intracellular amount of c-FLIP.","15371270","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"15749266",2005,"Early testicular effects in rats perinatally exposed to DEHP in combination with DEHA--apoptosis assessment and immunohistochemical studies.","15749266","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"15764490",2004,"Mono-(2-ethylhexyl) phthalate (MEHP) induces spermatogenic cell apoptosis in guinea pig testes at prepubertal stage in vitro.","15764490","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"15907966",2005,"Mono-(2-ethylhexyl) phthalate (MEHP) induces testicular alterations in male guinea pigs at prepubertal stage.","15907966","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"16141652",2005,"Influence of di-(2-ethylhexyl)phthalate on fetal testicular development by oral administration to pregnant rats.","16141652","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"16303285",2006,"Testicular toxicity of DEHP, but not DEHA, is elevated under conditions of thioacetamide-induced liver damage.","16303285","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"16678996",2006,"Effect of di-(2-ethylhexyl) phthalate on N-cadherin and catenin protein expression in rat testis.","16678996","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"16690193",2006,"Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis.","16690193","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"16806631",2006,"A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): effects on androgenic status, developmental landmarks and testicular histology in male offspring rats.","16806631","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"16809437",2006,"Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages.","16809437","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"16855774",2007,"Short-term effects of di-(2-ethylhexyl) phthalate on testes, liver, kidneys and pancreas in mice.","16855774","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"16952438",2006,"Toxicity of di(2-ethylhexyl)phthalate (DEHP) and di(2-ethylhexyl)adipate (DEHA) under conditions of renal dysfunction induced with folic acid in rats: enhancement of male reproductive toxicity of DEHP is associated with an increase of the mono-derivative.","16952438","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"16979278",2006,"Effect of in utero exposure to di-(2-ethylhexyl)phthalate: distribution in the rat fetus and testosterone production by rat fetal testis in culture.","16979278","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"16996189",2006,"A dose response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult male offspring rats.","16996189","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"17009524",2006,"[Di(2-ethylhexyl) phthalate affects the testes and leydig cells of neonatal KM mice].","17009524","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"17380854",2007,"An ultrastructural study on the effects of mono(2-ethylhexyl) phthalate on mice testes: cell death and sloughing of spermatogenic cells.","17380854","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"17400582",2007,"Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes.","17400582","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"17462840",2007,"Differential expression of the phthalate syndrome in male Sprague-Dawley and Wistar rats after in utero DEHP exposure.","17462840","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"18077825",2008,"Mono-(2-ethylhexyl) phthalate increases spermatocyte mitochondrial peroxiredoxin 3 and cyclooxygenase 2.","18077825","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"1816082",1991,"Effect of in utero exposure to di(2-ethylhexyl)phthalate on rat testes.","1816082","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"18322279",2008,"In utero exposure to di-(2-ethylhexyl) phthalate exerts both short-term and long-lasting suppressive effects on testosterone production in the rat.","18322279","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"18534133",2008,"Effects of diethylhexyl phthalate (DEHP) on INSL3 mRNA expression by Leydig cells derived from mouse embryos and in newborn mice.","18534133","Diethylhexyl Phthalate","Testis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1220,I1220)","v":"Diethylhexyl Phthalate"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1220,J1220)","v":"Testis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1220,H1220)","v":"18755736"},2008,"Cross-talk between the Akt and NF-kappaB signaling pathways inhibits MEHP-induced germ cell apoptosis.","18755736","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"19038859",2009,"TNF alpha-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents is partially regulated by MMP2.","19038859","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"19240039",2009,"Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis.","19240039","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"19330368",2009,"Reproductive effects of di(2-ethylhexyl)phthalate in immature male rats and its relation to cholesterol, testosterone, and thyroxin levels.","19330368","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"19452688",2009,"[Effects of Di (2-ethylhexyl) phthalate on the testis and testicular gubernaculum of fetal KM mice].","19452688","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"19756843",2009,"Vitamin C and resveratrol supplementation to rat dams treated with di(2-ethylhexyl)phthalate: impact on reproductive and oxidative stress end points in male offspring.","19756843","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"19819939",2009,"In utero exposure to di-(2-ethylhexyl) phthalate decreases mineralocorticoid receptor expression in the adult testis.","19819939","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"19912166",2010,"Dynamic epigenetic changes involved in testicular toxicity induced by di-2-(ethylhexyl) phthalate in mice.","19912166","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"20100735",2010,"FasL gene-deficient mice display a limited disruption in spermatogenesis and inhibition of mono-(2-ethylhexyl) phthalate-induced germ cell apoptosis.","20100735","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"20112733",2009,"[Di-(2-ethylhexyl) phthalate increases the DNA methylation level of genomes in the mouse testis].","20112733","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"20420898",2010,"Low-dose perinatal exposure to di(2-ethylhexyl) phthalate induces anti-androgenic effects in male rats.","20420898","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"21515331",2011,"Induction of ROS, p53, p21 in DEHP- and MEHP-exposed LNCaP cells-protection by selenium compounds.","21515331","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"21714771",2011,"Reproductive toxicity of di(2-ethylhexyl) phthalate in selenium-supplemented and selenium-deficient rats.","21714771","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"22147016",2012,"Exposure to di(2-ethyl-hexyl) phthalate (DEHP) in utero and during lactation causes long-term pituitary-gonadal axis disruption in male and female mouse offspring.","22147016","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"22178135",2012,"Different effects by sex on hypothalamic-pituitary axis of prepubertal offspring rats produced by in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP).","22178135","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"22293410",2012,"Metabolism of di (2-ethylhexyl) phthalate (DEHP): comparative study in juvenile and fetal marmosets and rats.","22293410","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"22402212",2012,"Human testis steroidogenesis is inhibited by phthalates.","22402212","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"22462442",2012,"Two generation reproductive and developmental toxicity following subchronic exposure of pubescent male mice to di(2-ethylhexyl)phthalate.","22462442","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"22828881",2011,"Effects of perinatal exposure to bisphenol A and di(2-ethylhexyl)-phthalate on gonadal development of male mice.","22828881","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"23041310",2012,"Non-monotonic dose effects of in utero exposure to di(2-ethylhexyl) phthalate (DEHP) on testicular and serum testosterone and anogenital distance in male mouse fetuses.","23041310","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"23041508",2012,"Novel molecular targets associated with testicular dysgenesis induced by gestational exposure to diethylhexyl phthalate in the rat: a role for estradiol.","23041508","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"23118965",2012,"Cellular and molecular effect of MEHP Involving LXR? in human fetal testis and ovary.","23118965","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"23226291",2012,"The effects of Di-(2-ethylhexyl)-phthalate exposure on fertilization and embryonic development in vitro and testicular genomic mutation in vivo.","23226291","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"23391632",2013,"The increased number of Leydig cells by di(2-ethylhexyl) phthalate comes from the differentiation of stem cells into Leydig cell lineage in the adult rat testis.","23391632","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"23536373",2013,"Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice.","23536373","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"23892333",2013,"Effects on the local immunity in the testis by exposure to di-(2-ethylhexyl) phthalate (DEHP) in mice.","23892333","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"23959011",2013,"Disruption of reproductive development in male rat offspring following gestational and lactational exposure to di-(2-ethylhexyl) phthalate and genistein.","23959011","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"24057186",2013,"Effects of diethylhexyl phthalate (DEHP) given neonatally on spermatogenesis of mice.","24057186","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"2879365",1986,"Effect of di(2-ethylhexyl)phthalate (DEHP) on spermatogenesis in adult rats.","2879365","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"2881530",1986,"Testicular atrophy induced by di(2-ethylhexyl)phthalate: changes in histology, cell specific enzyme activities and zinc concentrations in rat testis.","2881530","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"3709450",1986,"Genetic toxicology of phthalate esters: mutagenic and other genotoxic effects.","3709450","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"3709461",1986,"Effects of di(2-ethylhexyl) phthalate on the gonadal pathophysiology, sperm morphology, and reproductive performance of male rats.","3709461","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",0,1,"3716815",1986,"Effects of di-(2-ethylhexyl) phthalate and five of its metabolites on rat testis in vivo and in in vitro.","3716815","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"3967638",1985,"Reversibility of testicular atrophy induced by Di(2-ethylhexyl) phthalate in rats.","3967638","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"6386344",1984,"Biological effects of di-(2-ethylhexyl) phthalate and other phthalic acid esters.","6386344","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"8540215",1995,"Testicular toxicity of Di(2-ethylhexyl)phthalate in developing rats.","8540215","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"8607140",1996,"Mono-(2-ethylhexyl) phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes.","8607140","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylhexyl Phthalate","Testis",1,1,"9771559",1998,"Oral toxicity of bis(2-ethylhexyl) phthalate during pregnancy and suckling in the Long-Evans rat.","9771559","Diethylhexyl Phthalate","Testis",1,null,1]
["Diethylstilbestrol","Acrosome",0,1,"15036965",2004,"Body and organ weight, sperm acrosomal status and reproduction after genistein and diethylstilbestrol treatment of CD1 mice in a multigenerational study.","15036965","Diethylstilbestrol","Acrosome",1,1,1]
["Diethylstilbestrol","Androgen-Insensitivity Syndrome",1,1,"10492898",1999,"The avian egg as a test system for endocrine disrupters: effects of diethylstilbestrol and ethynylestradiol on sex organ development.","10492898","Diethylstilbestrol","Androgen-Insensitivity Syndrome",1,1,1]
["Diethylstilbestrol","Androgen-Insensitivity Syndrome",1,1,"2146621",1990,"[Ingestion of diethylstilbestrol during pregnancy. Its responsibility in the testicular feminization syndrome].","2146621","Diethylstilbestrol","Androgen-Insensitivity Syndrome",1,1,1]
["Diethylstilbestrol","Androgen-Insensitivity Syndrome",1,1,"4466699",1974,"Hormone-induced disturbances in sexual differentiation.","4466699","Diethylstilbestrol","Androgen-Insensitivity Syndrome",1,1,1]
["Diethylstilbestrol","Androgen-Insensitivity Syndrome",0,1,"6721219",1984,"Induction of Müllerian duct derivatives in testicular feminized (Tfm) mice by prenatal exposure to diethylstilbestrol.","6721219","Diethylstilbestrol","Androgen-Insensitivity Syndrome",1,1,1]
["Diethylstilbestrol","Androgen-Insensitivity Syndrome",0,1,"7104403",1982,"[Feminization of embryonic chicken testicle by diethylstilbestrol and antagonistic action of tamoxifen].","7104403","Diethylstilbestrol","Androgen-Insensitivity Syndrome",1,1,1]
["Diethylstilbestrol","Blood-Testis Barrier",0,1,"11330641",2001,"Neonatally administered diethylstilbestrol retards the development of the blood-testis barrier in the rat.","11330641","Diethylstilbestrol","Blood-Testis Barrier",1,1,1]
["Diethylstilbestrol","Bulbourethral Glands",0,1,"1121332",1975,"Effects of diethylstilbestrol and testosterone propionate implanted in the hypothalamus on spermatogenesis in rats.","1121332","Diethylstilbestrol","Bulbourethral Glands",1,1,1]
["Diethylstilbestrol","Bulbourethral Glands",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Diethylstilbestrol","Bulbourethral Glands",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"10650968",2000,"Involvement of insulin-like factor 3 (Insl3) in diethylstilbestrol-induced cryptorchidism.","10650968","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"12638168",2003,"[A review of epidemiological studies about the incidence and etiological factors of cryptorchidism--relevance to endocrine-disrupting chemicals].","12638168","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",0,0,"14130828",1964,"THE HORMONES AND PUBERTY.","14130828","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"14781",1977,"Induction of urogenital anomalies and some tumors in the progeny of mice receiving diethylstilbestrol during pregnancy.","14781","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",0,1,"15130",1977,"Lack of influence of hypophysectomy on estrogen-induced DNA synthesis in Leydig cells of BALB/c mice.","15130","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"16020417",2005,"The health effects of diethylstilbestrol revisited.","16020417","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"19493424",2009,"Prenatal exposure to diaethylstilbestrol in the rat inhibits transabdominal testicular descent with involvement of the INSL3/LGR8 system and HOXA10.","19493424","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"19534997",2009,"[The effect of diethylstilbestrol on inducing abdominal cryptorchidism and relevant genetic expression in rats].","19534997","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"19689815",2009,"Urogenital abnormalities in men exposed to diethylstilbestrol in utero: a cohort study.","19689815","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"22945456",2012,"Diethylstilbestrol impairs the morphology and function of mouse gubernaculum testis in culture.","22945456","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"242076",1975,"Reproductive tract lesions in male mice exposed prenatally to diethylstilbestrol.","242076","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"37020",1979,"Physician advisory: health effects of the pregnancy use of diethylstilbestrol.","37020","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"37351",1979,"Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities.","37351","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",0,1,"41978",1979,"Plasma testosterone concentrations in normal and estrogen treated mice of three strains differing in susceptibility to induction of Leydig cell tumors.","41978","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",0,1,"4389146",1969,"Effect of diethylstilbestrol on enzymes of cryptochid mouse testes of Balb-c mice.","4389146","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",0,1,"4390313",1969,"A histochemical study of the effect of estrogen on oxidative enzymes in the testes of cryptorchid BALB/c mice.","4390313","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",0,1,"4399709",1970,"Changes in testicular DNA produced in BALB-c mice by diethylstilbestrol.","4399709","Diethylstilbestrol","Cryptorchidism",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1284,I1284)","v":"Diethylstilbestrol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1284,J1284)","v":"Cryptorchidism"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1284,H1284)","v":"4404717"},1972,"[Mechanism of action of testosterone on the gonads of male rats treated with stilbestrol].","4404717","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"6113570",1981,"Screening of adolescents exposed to diethylstilbestrol in utero.","6113570","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",0,1,"6113890",1981,"Effects of cryptorchidy, parabiosis, and estrogen administration upon Leydig cell tumorigenesis in Fischer rats.","6113890","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",1,1,"6121486",1982,"In utero exposure to diethylstilbestrol: adverse effects on the reproductive tract and reproductive performance and male and female offspring.","6121486","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Cryptorchidism",0,1,"9472934",1998,"Effects of neonatal administration of diethylstilbestrol in male hamsters: disruption of reproductive function in adults after apparently normal pubertal development.","9472934","Diethylstilbestrol","Cryptorchidism",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",0,0,"14063709",1963,"FETAL EFFECTS OF STEROID THERAPY DURING PREGNANCY.","14063709","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",0,0,"14102662",1964,"[ON EXTREME SEXUAL DIMORPHISM IN THE GROWTH OF THE MUSCOVY  DUCK, CAIRINA MOSCHATA FLEMM. V. GROWTH OF THE LONG BONES AND ITS CONTROL BY DIETHYLSTILBESTROL].","14102662","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",0,0,"3713734",1986,"Nuclear aberrations and loss of synaptonemal complexes in response to diethylstilbestrol (DES) in Caenorhabditis elegans hermaphrodites.","3713734","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",1,1,"3796650",1986,"Prenatal diethylstilbestrol exposure: behavioral consequences in humans.","3796650","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",1,1,"4466699",1974,"Hormone-induced disturbances in sexual differentiation.","4466699","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",0,0,"4954775",1965,"[Intersexuality in the quail (Coturnix coturnix). Production of a case of ovulation by a genetic male].","4954775","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",0,1,"4979275",1969,"[Action of diethylstilbestrol on the hybrid from the crossBarbariedrake x Khaki Campbellduck].","4979275","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",1,1,"5927979",1966,"[On fetal hermaphroditism formation due to stilbestrol].","5927979","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",1,1,"6199525",1984,"Squamous metaplasia of the verumontanum with obstruction due to hypertrophy: long-term effects of estrogen on the prostate in an aging male-to-female transsexual.","6199525","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",1,1,"6256027",1980,"[Embryogenesis and early postnatal development of rats following transplacental sex hormone administration].","6256027","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Disorders of Sex Development",0,1,"7429071",1980,"Induction of H-Y antigen in the gonads of male quail embryos by diethylstilbestrol.","7429071","Diethylstilbestrol","Disorders of Sex Development",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"10536110",1999,"Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero.","10536110","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",0,1,"11207210",2001,"Diethylstilbestrol-treated adult rats with altered epididymal sperm numbers and sperm motility parameters, but without alterations in sperm production and sperm morphology.","11207210","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",0,1,"1121332",1975,"Effects of diethylstilbestrol and testosterone propionate implanted in the hypothalamus on spermatogenesis in rats.","1121332","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"1171234",1975,"Follow-up study of male and female offspring of DES-treated mothers a preliminary report.","1171234","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"15800398",2005,"Effects of maternal exposure to a low dose of diethylstilbestrol on sexual dimorphic nucleus volume and male reproductive system in rat offspring.","15800398","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",0,1,"15855622",2005,"Neonatal treatment of rats with diethylstilboestrol (DES) induces stromal-epithelial abnormalities of the vas deferens and cauda epididymis in adulthood following delayed basal cell development.","15855622","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",0,1,"17213693",2006,"Progression of the dose-related effects of estrogenic endocrine disruptors, an important factor in declining fertility, differs between the hypothalamo-pituitary axis and reproductive organs of male mice.","17213693","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"17928631",2008,"Activin A and equine chorionic gonadotropin recover reproductive dysfunction induced by neonatal exposure to an estrogenic endocrine disruptor in adult male mice.","17928631","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"19346712",2009,"Effects of maternal exposure to diethylstilbestrol on epididymal development in rat offspring.","19346712","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"242076",1975,"Reproductive tract lesions in male mice exposed prenatally to diethylstilbestrol.","242076","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"3289905",1988,"Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure.","3289905","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"37351",1979,"Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities.","37351","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"3851834",1985,"Effects of in utero exposure to DES on male progeny.","3851834","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"492788",1979,"Diethylstilbestrol exposure in utero.","492788","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"6113570",1981,"Screening of adolescents exposed to diethylstilbestrol in utero.","6113570","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"6827710",1983,"Seminoma and epididymal cysts in a young man with known diethylstilbestrol exposure in utero.","6827710","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"772199",1976,"Structural and functional abnormalities in the sex organs of male offspring of mothers treated with diethylstilbestrol (DES).","772199","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"8274821",1993,"Effect of testosterone on diethylstilbestrol toxicity and comparison to a recovery study in the rat epididymis and vas deferens.","8274821","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"862278",1977,"Stilboestrol and human cancer.","862278","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",1,1,"9114336",1997,"Reproductive toxicology. Diethylstilbestrol.","9114336","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Epididymis",0,1,"9472934",1998,"Effects of neonatal administration of diethylstilbestrol in male hamsters: disruption of reproductive function in adults after apparently normal pubertal development.","9472934","Diethylstilbestrol","Epididymis",1,1,1]
["Diethylstilbestrol","Genital Neoplasms, Male",1,1,"10874014",2000,"Proliferative lesions and reproductive tract tumors in male descendants of mice exposed developmentally to diethylstilbestrol.","10874014","Diethylstilbestrol","Genital Neoplasms, Male",1,1,1]
["Diethylstilbestrol","Genital Neoplasms, Male",1,1,"1445734",1992,"Diethylstilboestrol: II, pharmacology, toxicology and carcinogenicity in experimental animals.","1445734","Diethylstilbestrol","Genital Neoplasms, Male",1,1,1]
["Diethylstilbestrol","Genital Neoplasms, Male",1,1,"16690809",2006,"Adverse effects of the model environmental estrogen diethylstilbestrol are transmitted to subsequent generations.","16690809","Diethylstilbestrol","Genital Neoplasms, Male",1,1,1]
["Diethylstilbestrol","Genital Neoplasms, Male",1,1,"2680951",1989,"Epidemiological studies of the effects of diethylstilboestrol.","2680951","Diethylstilbestrol","Genital Neoplasms, Male",1,1,1]
["Diethylstilbestrol","Genital Neoplasms, Male",1,1,"2680952",1989,"Animal models of prenatal exposure to diethylstilboestrol.","2680952","Diethylstilbestrol","Genital Neoplasms, Male",1,1,1]
["Diethylstilbestrol","Genital Neoplasms, Male",1,1,"3850790",1985,"Physical and psychological effects of DES on exposed offspring.","3850790","Diethylstilbestrol","Genital Neoplasms, Male",1,1,1]
["Diethylstilbestrol","Genital Neoplasms, Male",1,1,"6361926",1983,"[Administration of diethylstilbestrol during pregnancy, a public health problem].","6361926","Diethylstilbestrol","Genital Neoplasms, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"10806412",2000,"Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals.","10806412","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"11114983",2000,"Reproductive function in male rats after brief in utero exposure to diethylstilboestrol.","11114983","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"11469497",2001,"From malformations to molecular mechanisms in the male: three decades of research on endocrine disrupters.","11469497","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"15800398",2005,"Effects of maternal exposure to a low dose of diethylstilbestrol on sexual dimorphic nucleus volume and male reproductive system in rat offspring.","15800398","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"16804812",2006,"Does our environment affect our fertility? Some examples to help reframe the question.","16804812","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"17596265",2007,"Time to pregnancy and secondary sex ratio in men exposed prenatally to diethylstilbestrol.","17596265","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"2680952",1989,"Animal models of prenatal exposure to diethylstilboestrol.","2680952","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"2888216",1987,"Müllerian remnants of male mice exposed prenatally to diethylstilbestrol.","2888216","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"3156531",1985,"[Effect of sex steroids on the reproductive system of progeny].","3156531","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"318736",1977,"Follow-up study of male and female offspring of DES-exposed mothers.","318736","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"376358",1979,"Fertility of the diethylstilbestrol-exposed offspring.","376358","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"3851834",1985,"Effects of in utero exposure to DES on male progeny.","3851834","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"3959533",1986,"Sperm counts and reproductive tract lesions in male Syrian hamsters exposed in utero to diethylstilbestrol.","3959533","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",0,1,"442345",1979,"Transplacental exposure to diethylstilbestrol in men.","442345","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"481582",1979,"Transplacental effects of diethylstilbestrol in mice.","481582","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",0,1,"5021092",1972,"[Medico-biological studies relating to the use of estrogens as growth stimulators].","5021092","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",0,1,"5151011",1971,"[Action of testosterone on the genital tract of the male rat treated with stilbestrol].","5151011","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"6121486",1982,"In utero exposure to diethylstilbestrol: adverse effects on the reproductive tract and reproductive performance and male and female offspring.","6121486","Diethylstilbestrol","Genitalia, Male",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1348,I1348)","v":"Diethylstilbestrol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1348,J1348)","v":"Genitalia, Male"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1348,H1348)","v":"6256027"},1980,"[Embryogenesis and early postnatal development of rats following transplacental sex hormone administration].","6256027","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"6368486",1984,"Diethylstilbestrol exposure in utero: review of literature.","6368486","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"6397835",1984,"[Fertility disorders attributable to the use of diethylstilbestrol during intrauterine life].","6397835","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"6436071",1984,"Genital tract examinations and zona-free hamster egg penetration tests from men exposed in utero to diethylstilbestrol.","6436071","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"6940004",1981,"DES story; review and report.","6940004","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"7024873",1981,"The current status of the DES-exposed population.","7024873","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"7335401",1981,"Management of the adolescent girl exposed in utero to DES.","7335401","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"7463583",1981,"Genital abnormalities and abnormal semen analyses in male patients exposed to diethylstilbestrol in utero.","7463583","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"772199",1976,"Structural and functional abnormalities in the sex organs of male offspring of mothers treated with diethylstilbestrol (DES).","772199","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"7723797",1995,"Fertility in men exposed prenatally to diethylstilbestrol.","7723797","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"833973",1977,"Male genitourinary abnormalities and maternal diethylstilbestrol.","833973","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"8479275",1993,"[Diethylstilbestrol. Tragic late effect after prenatal exposure].","8479275","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",0,1,"8491155",1993,"Estrogen receptors, estradiol, and diethylstilbestrol in early development: the mouse as a model for the study of estrogen receptors and estrogen sensitivity in embryonic development of male and female reproductive tracts.","8491155","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",1,1,"890793",1977,"[Danger in the prenatal administration of diethylstilbestrol (Agostilben) for male offsprings].","890793","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Genitalia, Male",0,1,"9472934",1998,"Effects of neonatal administration of diethylstilbestrol in male hamsters: disruption of reproductive function in adults after apparently normal pubertal development.","9472934","Diethylstilbestrol","Genitalia, Male",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"11748570",2002,"Characterization of diethylstilbestrol-induced hypospadias in female mice.","11748570","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"11943252",2002,"Iatrogenic legacy from diethylstilbestrol exposure.","11943252","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"11943257",2002,"Hypospadias in sons of women exposed to diethylstilbestrol in utero: a cohort study.","11943257","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"15906411",2005,"Hypospadias in sons of women exposed to diethylstilbestrol in utero.","15906411","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"15951681",2005,"Hypospadias in sons of women exposed to diethylstilbestrol in utero.","15951681","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"16293648",2006,"Hypospadias: a transgenerational effect of diethylstilbestrol?","16293648","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"16302166",2005,"Hypospadias in sons of women exposed to ditheylstilbestrol: a true trans-generational effect?","16302166","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"21458804",2011,"Prevalence of hypospadias in grandsons of women exposed to diethylstilbestrol during pregnancy: a multigenerational national cohort study.","21458804","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"454458",1979,"Teratogenesis and carcinogenesis in rat offspring after transplacental and transmammary exposure to diethylstilbestrol.","454458","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"6645389",1983,"Radiologic diagnosis of diethylstilbestrol induced teratogenesis in rats.","6645389","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,0,"6740514",1984,"Direct fetal injections of diethylstilbestrol and 17 beta-estradiol: a method for investigating their teratogenicity.","6740514","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Hypospadias",1,1,"972792",1976,"Urogenital tract abnormalities in sons of women treated with diethylstilbestrol.","972792","Diethylstilbestrol","Hypospadias",1,1,1]
["Diethylstilbestrol","Klinefelter Syndrome",0,1,"1218535",1975,"[Estimation of the androgenic function of the adrenals and gonads in the course of hormonal therapy in some somato-genital disorders].","1218535","Diethylstilbestrol","Klinefelter Syndrome",1,1,1]
["Diethylstilbestrol","Klinefelter Syndrome",0,0,"14130828",1964,"THE HORMONES AND PUBERTY.","14130828","Diethylstilbestrol","Klinefelter Syndrome",1,1,1]
["Diethylstilbestrol","Klinefelter Syndrome",0,0,"14238690",1965,"MALE BREAST CANCER IN KLINEFELTER'S SYNDROME.","14238690","Diethylstilbestrol","Klinefelter Syndrome",1,1,1]
["Diethylstilbestrol","Leydig Cell Tumor",0,1,"15130",1977,"Lack of influence of hypophysectomy on estrogen-induced DNA synthesis in Leydig cells of BALB/c mice.","15130","Diethylstilbestrol","Leydig Cell Tumor",1,1,1]
["Diethylstilbestrol","Leydig Cell Tumor",1,1,"3682076",1987,"Testicular tumors in mice exposed in utero to diethylstilbestrol.","3682076","Diethylstilbestrol","Leydig Cell Tumor",1,1,1]
["Diethylstilbestrol","Leydig Cell Tumor",0,1,"41978",1979,"Plasma testosterone concentrations in normal and estrogen treated mice of three strains differing in susceptibility to induction of Leydig cell tumors.","41978","Diethylstilbestrol","Leydig Cell Tumor",1,1,1]
["Diethylstilbestrol","Leydig Cell Tumor",0,1,"6113890",1981,"Effects of cryptorchidy, parabiosis, and estrogen administration upon Leydig cell tumorigenesis in Fischer rats.","6113890","Diethylstilbestrol","Leydig Cell Tumor",1,1,1]
["Diethylstilbestrol","Leydig Cells",1,1,"10470413",1999,"Morphometric studies on the testes of rats treated neonatally with oestrogen and subsequently with gonadotrophins and testosterone.","10470413","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",1,1,"10650968",2000,"Involvement of insulin-like factor 3 (Insl3) in diethylstilbestrol-induced cryptorchidism.","10650968","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",1,1,"12657744",2003,"Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture.","12657744","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",0,1,"15130",1977,"Lack of influence of hypophysectomy on estrogen-induced DNA synthesis in Leydig cells of BALB/c mice.","15130","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",1,1,"17569695",2007,"Developmental changes in testicular sensitivity to estrogens throughout fetal and neonatal life.","17569695","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",1,1,"17888624",2008,"In vivo and in vitro effects of flutamide and diethylstilbestrol on fetal testicular steroidogenesis in the rat.","17888624","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",0,1,"23284716",2012,"Differential effects of bisphenol A and diethylstilbestrol on human, rat and mouse fetal leydig cell function.","23284716","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",1,1,"23314658",2013,"Brief maternal exposure of rats to the xenobiotics dibutyl phthalate or diethylstilbestrol alters adult-type Leydig cell development in male offspring.","23314658","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",0,1,"4389146",1969,"Effect of diethylstilbestrol on enzymes of cryptochid mouse testes of Balb-c mice.","4389146","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",0,1,"4390313",1969,"A histochemical study of the effect of estrogen on oxidative enzymes in the testes of cryptorchid BALB/c mice.","4390313","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",0,1,"5439563",1970,"Effect of estrogen, progesterone and their combination on the rat testis.","5439563","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",1,1,"6884275",1983,"Effects of continuous intravenous infusion of diethylstilbestrol into pregnant mice on fetus: testicular morphology at fetal and postnatal period.","6884275","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",0,1,"8603575",1996,"Expression of cytochrome P450 17alpha-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens.","8603575","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Leydig Cells",0,1,"8814535",1996,"Effects of in-utero exposure to zeranol or diethylstilboestrol on morphological development of the fetal testis in mice.","8814535","Diethylstilbestrol","Leydig Cells",1,1,1]
["Diethylstilbestrol","Penis",0,1,"1121332",1975,"Effects of diethylstilbestrol and testosterone propionate implanted in the hypothalamus on spermatogenesis in rats.","1121332","Diethylstilbestrol","Penis",1,1,1]
["Diethylstilbestrol","Penis",1,1,"4625739",1972,"[Action on the histology of the rat testis of a diet containing meat from calves with diethylstilbestrol implants].","4625739","Diethylstilbestrol","Penis",1,1,1]
["Diethylstilbestrol","Prostate",1,1,"10536110",1999,"Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero.","10536110","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",0,1,"1061475",1975,"Cytologic findings in female and male offspring of DES treated mothers.","1061475","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",1,1,"10806412",2000,"Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals.","10806412","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",0,1,"11011959",2000,"The role of estrogen receptor, androgen receptor and growth factors in diethylstilbestrol-induced programming of prostate differentiation.","11011959","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",0,1,"1121332",1975,"Effects of diethylstilbestrol and testosterone propionate implanted in the hypothalamus on spermatogenesis in rats.","1121332","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",0,0,"14177636",1964,"EFFECT OF PORTAL DIVERSION OF TESTICULAR BLOOD ON PROSTATIC SECRETION IN THE DOG.","14177636","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",1,1,"15867144",2005,"Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra.","15867144","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",1,1,"3343029",1988,"Temporal and spatial factors in diethylstilbestrol-induced squamous metaplasia of the developing human prostate.","3343029","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",0,1,"5151011",1971,"[Action of testosterone on the genital tract of the male rat treated with stilbestrol].","5151011","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",0,1,"5439563",1970,"Effect of estrogen, progesterone and their combination on the rat testis.","5439563","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",1,1,"7432722",1980,"Effects of prenatal maternal estrogen on the male urogenital system.","7432722","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",1,1,"8560954",1995,"Temporal and spatial factors in diethylstilbestrol-induced squamous metaplasia in the developing human prostate. II. Persistent changes after removal of diethylstilbestrol.","8560954","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",0,1,"9050904",1997,"Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses.","9050904","Diethylstilbestrol","Prostate",1,1,1]
["Diethylstilbestrol","Prostate",1,1,"9114336",1997,"Reproductive toxicology. Diethylstilbestrol.","9114336","Diethylstilbestrol","Prostate",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1412,I1412)","v":"Diethylstilbestrol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1412,J1412)","v":"Prostatic Neoplasms"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1412,H1412)","v":"10887780"},1999,"Ties that bind. Mothers, daughters and sons continue to feel effects of DES.","10887780","Diethylstilbestrol","Prostatic Neoplasms",1,1,1]
["Diethylstilbestrol","Prostatic Neoplasms",0,0,"14228526",1964,"MEASUREMENT OF CORTICOSTEROID-BINDING GLOBULIN IN MAN.","14228526","Diethylstilbestrol","Prostatic Neoplasms",1,1,1]
["Diethylstilbestrol","Prostatic Neoplasms",1,1,"1556766",1992,"DES-related cancers under renewed scrutiny.","1556766","Diethylstilbestrol","Prostatic Neoplasms",1,1,1]
["Diethylstilbestrol","Prostatic Neoplasms",1,1,"7062403",1982,"Diethylstilbestrol and immunologic sequelae.","7062403","Diethylstilbestrol","Prostatic Neoplasms",1,1,1]
["Diethylstilbestrol","Prostatic Neoplasms",0,1,"90738",1979,"[Assay of \"pregnancy alpha 2 glycoprotein\" in the serum of prostatic cancer patients and changes during estrogen therapy].","90738","Diethylstilbestrol","Prostatic Neoplasms",1,1,1]
["Diethylstilbestrol","Rete Testis",1,1,"10874014",2000,"Proliferative lesions and reproductive tract tumors in male descendants of mice exposed developmentally to diethylstilbestrol.","10874014","Diethylstilbestrol","Rete Testis",1,1,1]
["Diethylstilbestrol","Rete Testis",1,1,"3799821",1986,"Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis.","3799821","Diethylstilbestrol","Rete Testis",1,1,1]
["Diethylstilbestrol","Rete Testis",1,1,"4027990",1985,"Lesions of the rete testis in mice exposed prenatally to diethylstilbestrol.","4027990","Diethylstilbestrol","Rete Testis",1,1,1]
["Diethylstilbestrol","Seminal Vesicles",1,1,"10536110",1999,"Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero.","10536110","Diethylstilbestrol","Seminal Vesicles",1,1,1]
["Diethylstilbestrol","Seminal Vesicles",0,1,"1121332",1975,"Effects of diethylstilbestrol and testosterone propionate implanted in the hypothalamus on spermatogenesis in rats.","1121332","Diethylstilbestrol","Seminal Vesicles",1,1,1]
["Diethylstilbestrol","Seminal Vesicles",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Diethylstilbestrol","Seminal Vesicles",1,1,1]
["Diethylstilbestrol","Seminal Vesicles",1,1,"15336712",2004,"Neonatal exposure to diethylstilbestrol leads to impaired action of androgens in adult male hamsters.","15336712","Diethylstilbestrol","Seminal Vesicles",1,1,1]
["Diethylstilbestrol","Seminal Vesicles",1,1,"17928631",2008,"Activin A and equine chorionic gonadotropin recover reproductive dysfunction induced by neonatal exposure to an estrogenic endocrine disruptor in adult male mice.","17928631","Diethylstilbestrol","Seminal Vesicles",1,1,1]
["Diethylstilbestrol","Seminal Vesicles",0,1,"2707167",1989,"Female gene expression in the seminal vesicle of mice after prenatal exposure to diethylstilbestrol.","2707167","Diethylstilbestrol","Seminal Vesicles",1,1,1]
["Diethylstilbestrol","Seminal Vesicles",0,1,"3216864",1988,"Prenatal exposure of male mice to diethylstilbestrol alter the expression of the lactotransferrin gene in seminal vesicles.","3216864","Diethylstilbestrol","Seminal Vesicles",1,1,1]
["Diethylstilbestrol","Seminal Vesicles",0,1,"4404717",1972,"[Mechanism of action of testosterone on the gonads of male rats treated with stilbestrol].","4404717","Diethylstilbestrol","Seminal Vesicles",1,1,1]
["Diethylstilbestrol","Seminal Vesicles",0,1,"5439563",1970,"Effect of estrogen, progesterone and their combination on the rat testis.","5439563","Diethylstilbestrol","Seminal Vesicles",1,1,1]
["Diethylstilbestrol","Seminal Vesicles",1,1,"8158792",1994,"Molecular feminization of mouse seminal vesicle by prenatal exposure to diethylstilbestrol: altered expression of messenger RNA.","8158792","Diethylstilbestrol","Seminal Vesicles",1,1,1]
["Diethylstilbestrol","Seminiferous Tubules",1,1,"10470413",1999,"Morphometric studies on the testes of rats treated neonatally with oestrogen and subsequently with gonadotrophins and testosterone.","10470413","Diethylstilbestrol","Seminiferous Tubules",1,1,1]
["Diethylstilbestrol","Seminiferous Tubules",1,1,"12071427",2002,"In utero exposure to diethylstilboestrol or 4-n-nonylphenol in rats: number of sertoli cells, diameter and length of seminiferous tubules estimated by stereological methods.","12071427","Diethylstilbestrol","Seminiferous Tubules",1,1,1]
["Diethylstilbestrol","Seminiferous Tubules",0,1,"12477725",2003,"Diethylstilbestrol induces rat spermatogenic cell apoptosis in vivo through increased expression of spermatogenic cell Fas/FasL system.","12477725","Diethylstilbestrol","Seminiferous Tubules",1,1,1]
["Diethylstilbestrol","Seminiferous Tubules",1,1,"17005366",2006,"Neonatal administration of diethylstilbestrol has adverse effects on somatic cells rather than germ cells.","17005366","Diethylstilbestrol","Seminiferous Tubules",1,1,1]
["Diethylstilbestrol","Seminiferous Tubules",1,1,"1719410",1991,"Testicular toxicity and mutagenicity of steroidal and non-steroidal estrogens in the male mouse.","1719410","Diethylstilbestrol","Seminiferous Tubules",1,1,1]
["Diethylstilbestrol","Seminiferous Tubules",1,1,"18296022",2008,"Adult exposure to diethylstilbestrol induces spermatogenic cell apoptosis in vivo through increased oxidative stress in male hamster.","18296022","Diethylstilbestrol","Seminiferous Tubules",1,1,1]
["Diethylstilbestrol","Seminiferous Tubules",1,1,"19734697",2009,"Effects of maternal exposure to low doses of DES on testicular steroidogenesis and spermatogenesis in male rat offspring.","19734697","Diethylstilbestrol","Seminiferous Tubules",1,1,1]
["Diethylstilbestrol","Seminiferous Tubules",1,1,"3133925",1988,"Hormonal imprinting and damages caused by fetal steroid treatment. Influence of fetal treatment with pregnancy-protecting steroids (allylestrenol, diethylstilbestrol) on the effect of gonadotropin administered to cockerels perinatally and at the age of six weeks.","3133925","Diethylstilbestrol","Seminiferous Tubules",1,1,1]
["Diethylstilbestrol","Seminiferous Tubules",0,1,"6479374",1984,"Effect of stilboestrol dipropionate on the rate of spermatogenesis in KP and C57 mice and in their hybrids.","6479374","Diethylstilbestrol","Seminiferous Tubules",1,1,1]
["Diethylstilbestrol","Sertoli Cells",0,1,"11330641",2001,"Neonatally administered diethylstilbestrol retards the development of the blood-testis barrier in the rat.","11330641","Diethylstilbestrol","Sertoli Cells",1,1,1]
["Diethylstilbestrol","Sertoli Cells",1,1,"12071427",2002,"In utero exposure to diethylstilboestrol or 4-n-nonylphenol in rats: number of sertoli cells, diameter and length of seminiferous tubules estimated by stereological methods.","12071427","Diethylstilbestrol","Sertoli Cells",1,1,1]
["Diethylstilbestrol","Sertoli Cells",1,1,"12657744",2003,"Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture.","12657744","Diethylstilbestrol","Sertoli Cells",1,1,1]
["Diethylstilbestrol","Sertoli Cells",1,1,"21922642",2011,"Effects of in utero exposure to Bisphenol A or diethylstilbestrol on the adult male reproductive system.","21922642","Diethylstilbestrol","Sertoli Cells",1,1,1]
["Diethylstilbestrol","Sertoli Cells",0,1,"8814535",1996,"Effects of in-utero exposure to zeranol or diethylstilboestrol on morphological development of the fetal testis in mice.","8814535","Diethylstilbestrol","Sertoli Cells",1,1,1]
["Diethylstilbestrol","Sertoli Cells",0,1,"9780313",1998,"Abnormalities in functional development of the Sertoli cells in rats treated neonatally with diethylstilbestrol: a possible role for estrogens in Sertoli cell development.","9780313","Diethylstilbestrol","Sertoli Cells",1,1,1]
["Diethylstilbestrol","Sexual Infantilism",0,0,"14787987",1950,"[Effect of a synthetic estrogen (diethylstilbestrol) on growth; treatment of 4 cases of infantilism, with follow up of one case for a period of 4 years].","14787987","Diethylstilbestrol","Sexual Infantilism",1,1,1]
["Diethylstilbestrol","Sperm Count",0,1,"11207210",2001,"Diethylstilbestrol-treated adult rats with altered epididymal sperm numbers and sperm motility parameters, but without alterations in sperm production and sperm morphology.","11207210","Diethylstilbestrol","Sperm Count",1,1,1]
["Diethylstilbestrol","Sperm Count",0,1,"12611468",2002,"Environmental estrogens: roles in male reproductive tract problems and in breast cancer.","12611468","Diethylstilbestrol","Sperm Count",1,1,1]
["Diethylstilbestrol","Sperm Count",1,1,"16804812",2006,"Does our environment affect our fertility? Some examples to help reframe the question.","16804812","Diethylstilbestrol","Sperm Count",1,1,1]
["Diethylstilbestrol","Sperm Count",1,1,"20815788",2010,"Generation of reactive oxygen species in sperms of rats as an earlier marker for evaluating the toxicity of endocrine-disrupting chemicals.","20815788","Diethylstilbestrol","Sperm Count",1,1,1]
["Diethylstilbestrol","Sperm Count",0,1,"22569274",2012,"Delayed reproductive dysfunction in female rats induced by early life exposure to low-dose diethylstilbestrol.","22569274","Diethylstilbestrol","Sperm Count",1,1,1]
["Diethylstilbestrol","Sperm Count",1,1,"3851834",1985,"Effects of in utero exposure to DES on male progeny.","3851834","Diethylstilbestrol","Sperm Count",1,1,1]
["Diethylstilbestrol","Sperm Count",1,1,"3959533",1986,"Sperm counts and reproductive tract lesions in male Syrian hamsters exposed in utero to diethylstilbestrol.","3959533","Diethylstilbestrol","Sperm Count",1,1,1]
["Diethylstilbestrol","Sperm Count",0,1,"536320",1979,"Comparison of four levels of protein supplementation with and without oral DES on reproductive traits and testosterone of bulls.","536320","Diethylstilbestrol","Sperm Count",1,1,1]
["Diethylstilbestrol","Sperm Count",1,1,"6397835",1984,"[Fertility disorders attributable to the use of diethylstilbestrol during intrauterine life].","6397835","Diethylstilbestrol","Sperm Count",1,1,1]
["Diethylstilbestrol","Sperm Count",1,1,"6705758",1984,"DNA-damaging potential of diethylstilbestrol evaluated in the germ cell unscheduled DNA synthesis assay.","6705758","Diethylstilbestrol","Sperm Count",1,1,1]
["Diethylstilbestrol","Sperm Head",1,1,"1719410",1991,"Testicular toxicity and mutagenicity of steroidal and non-steroidal estrogens in the male mouse.","1719410","Diethylstilbestrol","Sperm Head",1,1,1]
["Diethylstilbestrol","Sperm Motility",0,1,"11207210",2001,"Diethylstilbestrol-treated adult rats with altered epididymal sperm numbers and sperm motility parameters, but without alterations in sperm production and sperm morphology.","11207210","Diethylstilbestrol","Sperm Motility",1,1,1]
["Diethylstilbestrol","Sperm Motility",1,1,"20815788",2010,"Generation of reactive oxygen species in sperms of rats as an earlier marker for evaluating the toxicity of endocrine-disrupting chemicals.","20815788","Diethylstilbestrol","Sperm Motility",1,1,1]
["Diethylstilbestrol","Sperm Motility",0,1,"485089",1979,"Induction of urogenital neoplasia and abnormalities from prenatal exposure to diethylstilbestrol.","485089","Diethylstilbestrol","Sperm Motility",1,1,1]
["Diethylstilbestrol","Sperm Motility",0,1,"536320",1979,"Comparison of four levels of protein supplementation with and without oral DES on reproductive traits and testosterone of bulls.","536320","Diethylstilbestrol","Sperm Motility",1,1,1]
["Diethylstilbestrol","Sperm Motility",1,1,"850321",1977,"Pathological semen and anatomical abnormalities of the genital tract in human male subjects exposed to diethylstilbestrol in utero.","850321","Diethylstilbestrol","Sperm Motility",1,1,1]
["Diethylstilbestrol","Sperm Tail",1,1,"6705758",1984,"DNA-damaging potential of diethylstilbestrol evaluated in the germ cell unscheduled DNA synthesis assay.","6705758","Diethylstilbestrol","Sperm Tail",1,1,1]
["Diethylstilbestrol","Spermatids",1,1,"17009535",2006,"[A preliminary study on the effect of prepubertal exposure of male rats to diethylstilbestrol on the apoptosis of spermatogenic cells after sexual maturation and its mechanism].","17009535","Diethylstilbestrol","Spermatids",1,1,1]
["Diethylstilbestrol","Spermatids",1,1,"1719410",1991,"Testicular toxicity and mutagenicity of steroidal and non-steroidal estrogens in the male mouse.","1719410","Diethylstilbestrol","Spermatids",1,1,1]
["Diethylstilbestrol","Spermatids",1,1,"6705758",1984,"DNA-damaging potential of diethylstilbestrol evaluated in the germ cell unscheduled DNA synthesis assay.","6705758","Diethylstilbestrol","Spermatids",1,1,1]
["Diethylstilbestrol","Spermatids",0,1,"9914384",1998,"Aging and diethylstilbestrol-induced aneuploidy in male germ cells: a transgenic mouse model.","9914384","Diethylstilbestrol","Spermatids",1,1,1]
["Diethylstilbestrol","Spermatocytes",0,1,"12477725",2003,"Diethylstilbestrol induces rat spermatogenic cell apoptosis in vivo through increased expression of spermatogenic cell Fas/FasL system.","12477725","Diethylstilbestrol","Spermatocytes",1,1,1]
["Diethylstilbestrol","Spermatocytes",1,1,"2899562",1988,"Infertility in a patient with abnormal spermatogenesis and in utero DES exposure.","2899562","Diethylstilbestrol","Spermatocytes",1,1,1]
["Diethylstilbestrol","Spermatocytes",1,1,"6705758",1984,"DNA-damaging potential of diethylstilbestrol evaluated in the germ cell unscheduled DNA synthesis assay.","6705758","Diethylstilbestrol","Spermatocytes",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"10470413",1999,"Morphometric studies on the testes of rats treated neonatally with oestrogen and subsequently with gonadotrophins and testosterone.","10470413","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"10536110",1999,"Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero.","10536110","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"1121332",1975,"Effects of diethylstilbestrol and testosterone propionate implanted in the hypothalamus on spermatogenesis in rats.","1121332","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"11330641",2001,"Neonatally administered diethylstilbestrol retards the development of the blood-testis barrier in the rat.","11330641","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"12211056",2002,"Toxicogenomic effects of neonatal exposure to diethylstilbestrol on mouse testicular gene expression in the long term: a study using cDNA microarray analysis.","12211056","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"12477725",2003,"Diethylstilbestrol induces rat spermatogenic cell apoptosis in vivo through increased expression of spermatogenic cell Fas/FasL system.","12477725","Diethylstilbestrol","Spermatogenesis",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1476,I1476)","v":"Diethylstilbestrol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1476,J1476)","v":"Spermatogenesis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1476,H1476)","v":"15336712"},2004,"Neonatal exposure to diethylstilbestrol leads to impaired action of androgens in adult male hamsters.","15336712","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"15800398",2005,"Effects of maternal exposure to a low dose of diethylstilbestrol on sexual dimorphic nucleus volume and male reproductive system in rat offspring.","15800398","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"15855622",2005,"Neonatal treatment of rats with diethylstilboestrol (DES) induces stromal-epithelial abnormalities of the vas deferens and cauda epididymis in adulthood following delayed basal cell development.","15855622","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"17005366",2006,"Neonatal administration of diethylstilbestrol has adverse effects on somatic cells rather than germ cells.","17005366","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"17928631",2008,"Activin A and equine chorionic gonadotropin recover reproductive dysfunction induced by neonatal exposure to an estrogenic endocrine disruptor in adult male mice.","17928631","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"18480992",2008,"Re-establishment of spermatogenesis by diethylstilbestrol after 2,5-hexanedione-induced irreversible testicular atrophy in rats.","18480992","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"19734697",2009,"Effects of maternal exposure to low doses of DES on testicular steroidogenesis and spermatogenesis in male rat offspring.","19734697","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"19884658",2009,"The orphan nuclear receptor small heterodimer partner mediates male infertility induced by diethylstilbestrol in mice.","19884658","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"21922642",2011,"Effects of in utero exposure to Bisphenol A or diethylstilbestrol on the adult male reproductive system.","21922642","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"2899562",1988,"Infertility in a patient with abnormal spermatogenesis and in utero DES exposure.","2899562","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"4404717",1972,"[Mechanism of action of testosterone on the gonads of male rats treated with stilbestrol].","4404717","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"4448499",1974,"Effect of stilbestrol on spermatogenesis of Rana hexadactyla Lesson.","4448499","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"4455575",1974,"Attempts at stimulation of spermatogenesis by testosterone in the rat treated with a single dose of stilboestrol on the first day of life.","4455575","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"4625739",1972,"[Action on the histology of the rat testis of a diet containing meat from calves with diethylstilbestrol implants].","4625739","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"475591",1979,"Induction of dominant lethal mutations in male mice by fosfestrol.","475591","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"5151011",1971,"[Action of testosterone on the genital tract of the male rat treated with stilbestrol].","5151011","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"6479374",1984,"Effect of stilboestrol dipropionate on the rate of spermatogenesis in KP and C57 mice and in their hybrids.","6479374","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"6733514",1984,"Pre- and postnatal influence of testosterone propionate and diethylstilbestrol on differentiation of the sexually dimorphic nucleus of the preoptic area in male and female rats.","6733514","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"6884275",1983,"Effects of continuous intravenous infusion of diethylstilbestrol into pregnant mice on fetus: testicular morphology at fetal and postnatal period.","6884275","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"7252950",1981,"The effects of prenatal diethylstilbestrol exposure on the genitalia of pubertal Macaca mulatta. II. Male offspring.","7252950","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"8274821",1993,"Effect of testosterone on diethylstilbestrol toxicity and comparison to a recovery study in the rat epididymis and vas deferens.","8274821","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",1,1,"8747020",1995,"Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production.","8747020","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"9472934",1998,"Effects of neonatal administration of diethylstilbestrol in male hamsters: disruption of reproductive function in adults after apparently normal pubertal development.","9472934","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogenesis",0,1,"9780313",1998,"Abnormalities in functional development of the Sertoli cells in rats treated neonatally with diethylstilbestrol: a possible role for estrogens in Sertoli cell development.","9780313","Diethylstilbestrol","Spermatogenesis",1,1,1]
["Diethylstilbestrol","Spermatogonia",1,1,"17005366",2006,"Neonatal administration of diethylstilbestrol has adverse effects on somatic cells rather than germ cells.","17005366","Diethylstilbestrol","Spermatogonia",1,1,1]
["Diethylstilbestrol","Spermatogonia",1,1,"20860625",2010,"Quercetin protects hamster spermatogenic cells from oxidative damage induced by diethylstilboestrol.","20860625","Diethylstilbestrol","Spermatogonia",1,1,1]
["Diethylstilbestrol","Spermatogonia",0,1,"3105256",1986,"Changes of free histones in chick testicular and ovarian cells after embryonic and/or neonatal treatment with diethylstilbestrol (DES) or allyloestrenol (AE).","3105256","Diethylstilbestrol","Spermatogonia",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"11207210",2001,"Diethylstilbestrol-treated adult rats with altered epididymal sperm numbers and sperm motility parameters, but without alterations in sperm production and sperm morphology.","11207210","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"1121332",1975,"Effects of diethylstilbestrol and testosterone propionate implanted in the hypothalamus on spermatogenesis in rats.","1121332","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"12130571",2002,"Gestational and lactational exposure of male mice to diethylstilbestrol causes long-term effects on the testis, sperm fertilizing ability in vitro, and testicular gene expression.","12130571","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,0,"12255249",1966,"Post-coital oral contraception.","12255249","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,0,"12335682",1977,"Fertility regulation technology:  status and prospects.","12335682","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,0,"13707021",1961,"The treatment of oligospermia with stilbestrol and vitamin B.","13707021","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,0,"14173939",1964,"[TREATMENT OF OLIGOSPERMIA WITH STILBESTEROL].","14173939","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"14648872",2004,"Toxicogenomic difference between diethylstilbestrol and 17beta-estradiol in mouse testicular gene expression by neonatal exposure.","14648872","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"15036965",2004,"Body and organ weight, sperm acrosomal status and reproduction after genistein and diethylstilbestrol treatment of CD1 mice in a multigenerational study.","15036965","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"1719410",1991,"Testicular toxicity and mutagenicity of steroidal and non-steroidal estrogens in the male mouse.","1719410","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"17569695",2007,"Developmental changes in testicular sensitivity to estrogens throughout fetal and neonatal life.","17569695","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"18296022",2008,"Adult exposure to diethylstilbestrol induces spermatogenic cell apoptosis in vivo through increased oxidative stress in male hamster.","18296022","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"20815788",2010,"Generation of reactive oxygen species in sperms of rats as an earlier marker for evaluating the toxicity of endocrine-disrupting chemicals.","20815788","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"20860625",2010,"Quercetin protects hamster spermatogenic cells from oxidative damage induced by diethylstilboestrol.","20860625","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"318736",1977,"Follow-up study of male and female offspring of DES-exposed mothers.","318736","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"37351",1979,"Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities.","37351","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"442345",1979,"Transplacental exposure to diethylstilbestrol in men.","442345","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"4577932",1973,"The use of estrogens as postcoital contraceptive agents. Clinical effectiveness and potential mode of action.","4577932","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"492788",1979,"Diethylstilbestrol exposure in utero.","492788","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"4936879",1971,"A review: relationships of some hormones to growth and carcass quality of ruminants.","4936879","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"5021092",1972,"[Medico-biological studies relating to the use of estrogens as growth stimulators].","5021092","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"5439563",1970,"Effect of estrogen, progesterone and their combination on the rat testis.","5439563","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"6502859",1984,"Males exposed in utero to diethylstilbestrol.","6502859","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"6705758",1984,"DNA-damaging potential of diethylstilbestrol evaluated in the germ cell unscheduled DNA synthesis assay.","6705758","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"7031540",1981,"Diethylstilbestrol and other sex hormones during pregnancy.","7031540","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"7351253",1980,"Reproductive history of women exposed to diethylstilbestrol in utero.","7351253","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"772199",1976,"Structural and functional abnormalities in the sex organs of male offspring of mothers treated with diethylstilbestrol (DES).","772199","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"8274821",1993,"Effect of testosterone on diethylstilbestrol toxicity and comparison to a recovery study in the rat epididymis and vas deferens.","8274821","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"850321",1977,"Pathological semen and anatomical abnormalities of the genital tract in human male subjects exposed to diethylstilbestrol in utero.","850321","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",0,1,"8949895",1996,"In situ demonstration of germinal cell apoptosis during diethylstilbestrol-induced testis regression in adult male Syrian hamsters.","8949895","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Spermatozoa",1,1,"992189",1976,"DES and pregnancy: lower reproductive tract changes in offspring.","992189","Diethylstilbestrol","Spermatozoa",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"10509096",1999,"DES plagues those exposed.","10509096","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"11252812",2000,"Intrauterine exposure to diethylstilbestrol: long-term effects in humans.","11252812","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"11287449",2001,"Cancer risk in men exposed in utero to diethylstilbestrol.","11287449","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",0,1,"12611468",2002,"Environmental estrogens: roles in male reproductive tract problems and in breast cancer.","12611468","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"12739463",2003,"DES may be forgotten, but it's not gone.","12739463","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1540,I1540)","v":"Diethylstilbestrol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1540,J1540)","v":"Testicular Neoplasms"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1540,H1540)","v":"1670552"},1990,"[Exposure to diethylstilbestrol during pregnancy as a cause for developmental abnormalities of the genitalia].","1670552","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"3225080",1988,"A case-control study of testicular cancer using Connecticut tumour registry data.","3225080","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"3289905",1988,"Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure.","3289905","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"3682076",1987,"Testicular tumors in mice exposed in utero to diethylstilbestrol.","3682076","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"37351",1979,"Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities.","37351","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"3799821",1986,"Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis.","3799821","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"398263",1979,"The effects of exogenous female hormones on the fetus.","398263","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"4027990",1985,"Lesions of the rete testis in mice exposed prenatally to diethylstilbestrol.","4027990","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"48129",1975,"Editorial: Prenatal cestrogen-continued.","48129","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",0,1,"481584",1979,"Role of hormone imbalance in transplacental carcinogenesis induced in Syrian golden hamsters by sex hormones.","481584","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",0,1,"6113890",1981,"Effects of cryptorchidy, parabiosis, and estrogen administration upon Leydig cell tumorigenesis in Fischer rats.","6113890","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"6493302",1984,"Diethylstilbestrol exposure--1984.","6493302","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"6502859",1984,"Males exposed in utero to diethylstilbestrol.","6502859","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"6827710",1983,"Seminoma and epididymal cysts in a young man with known diethylstilbestrol exposure in utero.","6827710","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"7717601",1995,"Diethylstilbestrol revisited: a review of the long-term health effects.","7717601","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testicular Neoplasms",1,1,"992189",1976,"DES and pregnancy: lower reproductive tract changes in offspring.","992189","Diethylstilbestrol","Testicular Neoplasms",1,1,1]
["Diethylstilbestrol","Testis",1,1,"10470413",1999,"Morphometric studies on the testes of rats treated neonatally with oestrogen and subsequently with gonadotrophins and testosterone.","10470413","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"10492898",1999,"The avian egg as a test system for endocrine disrupters: effects of diethylstilbestrol and ethynylestradiol on sex organ development.","10492898","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"10536110",1999,"Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero.","10536110","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"10650968",2000,"Involvement of insulin-like factor 3 (Insl3) in diethylstilbestrol-induced cryptorchidism.","10650968","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"10874014",2000,"Proliferative lesions and reproductive tract tumors in male descendants of mice exposed developmentally to diethylstilbestrol.","10874014","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"11140822",2000,"A dose-finding study of in utero and lactational exposure to diethylstilboestrol and flutamide in 129/Sv mice.","11140822","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"11207210",2001,"Diethylstilbestrol-treated adult rats with altered epididymal sperm numbers and sperm motility parameters, but without alterations in sperm production and sperm morphology.","11207210","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"1121332",1975,"Effects of diethylstilbestrol and testosterone propionate implanted in the hypothalamus on spermatogenesis in rats.","1121332","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"11330641",2001,"Neonatally administered diethylstilbestrol retards the development of the blood-testis barrier in the rat.","11330641","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"11403907",2001,"Prenatal testosterone and luteinizing hormone levels in male rats exposed during pregnancy to 2,3,7,8-tetrachlorodibenzo-p-dioxin and diethylstilbestrol.","11403907","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"12130571",2002,"Gestational and lactational exposure of male mice to diethylstilbestrol causes long-term effects on the testis, sperm fertilizing ability in vitro, and testicular gene expression.","12130571","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"12211056",2002,"Toxicogenomic effects of neonatal exposure to diethylstilbestrol on mouse testicular gene expression in the long term: a study using cDNA microarray analysis.","12211056","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"12446607",2002,"Induction of reproductive tract developmental abnormalities in the male rat by lowering androgen production or action in combination with a low dose of diethylstilbestrol: evidence for importance of the androgen-estrogen balance.","12446607","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"12477725",2003,"Diethylstilbestrol induces rat spermatogenic cell apoptosis in vivo through increased expression of spermatogenic cell Fas/FasL system.","12477725","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"12657744",2003,"Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture.","12657744","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,0,"14121626",1964,"IN VITRO EXPOSURE OF RABBIT OVA TO ESTROGENS.","14121626","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,0,"14177636",1964,"EFFECT OF PORTAL DIVERSION OF TESTICULAR BLOOD ON PROSTATIC SECRETION IN THE DOG.","14177636","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"14648872",2004,"Toxicogenomic difference between diethylstilbestrol and 17beta-estradiol in mouse testicular gene expression by neonatal exposure.","14648872","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"14781",1977,"Induction of urogenital anomalies and some tumors in the progeny of mice receiving diethylstilbestrol during pregnancy.","14781","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"15036965",2004,"Body and organ weight, sperm acrosomal status and reproduction after genistein and diethylstilbestrol treatment of CD1 mice in a multigenerational study.","15036965","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"15196701",2004,"Diethylstilbestrol inhibits the expression of the steroidogenic acute regulatory protein in mouse fetal testis.","15196701","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"15336712",2004,"Neonatal exposure to diethylstilbestrol leads to impaired action of androgens in adult male hamsters.","15336712","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"15546024",2004,"Effect of prenatal exposure to diethylstilbestrol on gubernacular development in fetal male mice.","15546024","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"16710698",2006,"In ovo exposure quail assay for risk assessment of endocrine disrupting chemicals.","16710698","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"16758213",2006,"Avian transgenerational reproductive toxicity test with in ovo exposure.","16758213","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"17005366",2006,"Neonatal administration of diethylstilbestrol has adverse effects on somatic cells rather than germ cells.","17005366","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"1719410",1991,"Testicular toxicity and mutagenicity of steroidal and non-steroidal estrogens in the male mouse.","1719410","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"17213693",2006,"Progression of the dose-related effects of estrogenic endocrine disruptors, an important factor in declining fertility, differs between the hypothalamo-pituitary axis and reproductive organs of male mice.","17213693","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"17569695",2007,"Developmental changes in testicular sensitivity to estrogens throughout fetal and neonatal life.","17569695","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"17888624",2008,"In vivo and in vitro effects of flutamide and diethylstilbestrol on fetal testicular steroidogenesis in the rat.","17888624","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"17928631",2008,"Activin A and equine chorionic gonadotropin recover reproductive dysfunction induced by neonatal exposure to an estrogenic endocrine disruptor in adult male mice.","17928631","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"18296022",2008,"Adult exposure to diethylstilbestrol induces spermatogenic cell apoptosis in vivo through increased oxidative stress in male hamster.","18296022","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"18480992",2008,"Re-establishment of spermatogenesis by diethylstilbestrol after 2,5-hexanedione-induced irreversible testicular atrophy in rats.","18480992","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"19534997",2009,"[The effect of diethylstilbestrol on inducing abdominal cryptorchidism and relevant genetic expression in rats].","19534997","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"19734697",2009,"Effects of maternal exposure to low doses of DES on testicular steroidogenesis and spermatogenesis in male rat offspring.","19734697","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"19884658",2009,"The orphan nuclear receptor small heterodimer partner mediates male infertility induced by diethylstilbestrol in mice.","19884658","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"21922642",2011,"Effects of in utero exposure to Bisphenol A or diethylstilbestrol on the adult male reproductive system.","21922642","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"22934511",2012,"[Diethylstilbestrol affects LGR8 expression in mouse gubernaculum testis].","22934511","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"22945456",2012,"Diethylstilbestrol impairs the morphology and function of mouse gubernaculum testis in culture.","22945456","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"23284716",2012,"Differential effects of bisphenol A and diethylstilbestrol on human, rat and mouse fetal leydig cell function.","23284716","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"23314658",2013,"Brief maternal exposure of rats to the xenobiotics dibutyl phthalate or diethylstilbestrol alters adult-type Leydig cell development in male offspring.","23314658","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"23620786",2013,"Diethylstilboestrol exposure does not reduce testosterone production in human fetal testis xenografts.","23620786","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"242076",1975,"Reproductive tract lesions in male mice exposed prenatally to diethylstilbestrol.","242076","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"2899562",1988,"Infertility in a patient with abnormal spermatogenesis and in utero DES exposure.","2899562","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"3105256",1986,"Changes of free histones in chick testicular and ovarian cells after embryonic and/or neonatal treatment with diethylstilbestrol (DES) or allyloestrenol (AE).","3105256","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"3124504",1987,"Effect of embryonic and/or neonatal diethylstilbestrol and allylestrenol treatment on postnatal development of the chick testis.","3124504","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"3133925",1988,"Hormonal imprinting and damages caused by fetal steroid treatment. Influence of fetal treatment with pregnancy-protecting steroids (allylestrenol, diethylstilbestrol) on the effect of gonadotropin administered to cockerels perinatally and at the age of six weeks.","3133925","Diethylstilbestrol","Testis",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1604,I1604)","v":"Diethylstilbestrol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1604,J1604)","v":"Testis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1604,H1604)","v":"3289905"},1988,"Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure.","3289905","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"3577593",1986,"Effect of centchroman on the genital organs of the offspring of rats when administered during lactation or during the neonatal period: a comparative study with ethynylestradiol and diethylstilbestrol.","3577593","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"3682076",1987,"Testicular tumors in mice exposed in utero to diethylstilbestrol.","3682076","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"37351",1979,"Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities.","37351","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"3799821",1986,"Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis.","3799821","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"3851834",1985,"Effects of in utero exposure to DES on male progeny.","3851834","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"3959533",1986,"Sperm counts and reproductive tract lesions in male Syrian hamsters exposed in utero to diethylstilbestrol.","3959533","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"4027990",1985,"Lesions of the rete testis in mice exposed prenatally to diethylstilbestrol.","4027990","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"4389146",1969,"Effect of diethylstilbestrol on enzymes of cryptochid mouse testes of Balb-c mice.","4389146","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"4390313",1969,"A histochemical study of the effect of estrogen on oxidative enzymes in the testes of cryptorchid BALB/c mice.","4390313","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"4399709",1970,"Changes in testicular DNA produced in BALB-c mice by diethylstilbestrol.","4399709","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"4404717",1972,"[Mechanism of action of testosterone on the gonads of male rats treated with stilbestrol].","4404717","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"4455575",1974,"Attempts at stimulation of spermatogenesis by testosterone in the rat treated with a single dose of stilboestrol on the first day of life.","4455575","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"4625739",1972,"[Action on the histology of the rat testis of a diet containing meat from calves with diethylstilbestrol implants].","4625739","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"481584",1979,"Role of hormone imbalance in transplacental carcinogenesis induced in Syrian golden hamsters by sex hormones.","481584","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"4936879",1971,"A review: relationships of some hormones to growth and carcass quality of ruminants.","4936879","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"5150475",1971,"Effects of oestrogen on the differentiation of some reproductive behaviours in male pigeons (Columba livia).","5150475","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"5151011",1971,"[Action of testosterone on the genital tract of the male rat treated with stilbestrol].","5151011","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"5439563",1970,"Effect of estrogen, progesterone and their combination on the rat testis.","5439563","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"6479374",1984,"Effect of stilboestrol dipropionate on the rate of spermatogenesis in KP and C57 mice and in their hybrids.","6479374","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"6489263",1984,"Müllerian duct maintenance in heterotypic organ culture after in vivo exposure to diethylstilbestrol.","6489263","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"6839243",1983,"Effect of in-utero exposure to diethylstilbestrol on age at onset of puberty and on postpubertal hormone levels in boys.","6839243","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"6884275",1983,"Effects of continuous intravenous infusion of diethylstilbestrol into pregnant mice on fetus: testicular morphology at fetal and postnatal period.","6884275","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"7104403",1982,"[Feminization of embryonic chicken testicle by diethylstilbestrol and antagonistic action of tamoxifen].","7104403","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"7252950",1981,"The effects of prenatal diethylstilbestrol exposure on the genitalia of pubertal Macaca mulatta. II. Male offspring.","7252950","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"7432722",1980,"Effects of prenatal maternal estrogen on the male urogenital system.","7432722","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"772199",1976,"Structural and functional abnormalities in the sex organs of male offspring of mothers treated with diethylstilbestrol (DES).","772199","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"850321",1977,"Pathological semen and anatomical abnormalities of the genital tract in human male subjects exposed to diethylstilbestrol in utero.","850321","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"8603575",1996,"Expression of cytochrome P450 17alpha-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens.","8603575","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"8747020",1995,"Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production.","8747020","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"8814535",1996,"Effects of in-utero exposure to zeranol or diethylstilboestrol on morphological development of the fetal testis in mice.","8814535","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"8949895",1996,"In situ demonstration of germinal cell apoptosis during diethylstilbestrol-induced testis regression in adult male Syrian hamsters.","8949895","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"9099904",1997,"Maternal oestrogen/xenoestrogen exposure alters expression of steroidogenic factor-1 (SF-1/Ad4BP) in the fetal rat testis.","9099904","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"9472934",1998,"Effects of neonatal administration of diethylstilbestrol in male hamsters: disruption of reproductive function in adults after apparently normal pubertal development.","9472934","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",1,1,"9647885",1998,"Endocrine disruptors and testis development.","9647885","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"9780313",1998,"Abnormalities in functional development of the Sertoli cells in rats treated neonatally with diethylstilbestrol: a possible role for estrogens in Sertoli cell development.","9780313","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Testis",0,1,"9914384",1998,"Aging and diethylstilbestrol-induced aneuploidy in male germ cells: a transgenic mouse model.","9914384","Diethylstilbestrol","Testis",1,1,1]
["Diethylstilbestrol","Turner Syndrome",1,0,"1082078",1975,"Endometrial carcinoma in Turner's syndrome following prolonged treatment with diethylstilbestrol.","1082078","Diethylstilbestrol","Turner Syndrome",1,1,1]
["Diethylstilbestrol","Turner Syndrome",1,0,"1137706",1975,"Oestrogen-induced endometrial carcinoma in a patient with gonadal dysgenesis.","1137706","Diethylstilbestrol","Turner Syndrome",1,1,1]
["Diethylstilbestrol","Turner Syndrome",1,0,"1137707",1975,"Endometrial carcinoma after cyclical oestrogen-progestogen therapy for Turner's syndrome.","1137707","Diethylstilbestrol","Turner Syndrome",1,1,1]
["Diethylstilbestrol","Turner Syndrome",0,0,"14126611",1963,"RECENT STUDIES ON PITUITARY AND OVARIAN FUNCTION IN MAN.","14126611","Diethylstilbestrol","Turner Syndrome",1,1,1]
["Diethylstilbestrol","Turner Syndrome",0,0,"14281462",1965,"MENSTRUATION AND THE ADOLESCENT.","14281462","Diethylstilbestrol","Turner Syndrome",1,1,1]
["Diethylstilbestrol","Turner Syndrome",0,1,"3137241",1988,"Modulation of serum follicle-stimulating hormone bioactivity and isoform distribution by estrogenic steroids in normal women and in gonadal dysgenesis.","3137241","Diethylstilbestrol","Turner Syndrome",1,1,1]
["Diethylstilbestrol","Turner Syndrome",1,0,"4721406",1973,"Turner's syndrome with endometrial adenocarcinoma and stilbestrol therapy.","4721406","Diethylstilbestrol","Turner Syndrome",1,1,1]
["Diethylstilbestrol","Turner Syndrome",1,0,"5076457",1972,"Endometrial carcinoma after stilbestrol therapy in gonadal dysgenesis.","5076457","Diethylstilbestrol","Turner Syndrome",1,1,1]
["Diethylstilbestrol","Urethra",1,1,"11748570",2002,"Characterization of diethylstilbestrol-induced hypospadias in female mice.","11748570","Diethylstilbestrol","Urethra",1,1,1]
["Diethylstilbestrol","Urethra",1,1,"14746342",2003,"Effects of maternal exposure to diethylstilbestrol on the development of the reproductive system and thyroid function in male and female rat offspring.","14746342","Diethylstilbestrol","Urethra",1,1,1]
["Diethylstilbestrol","Urethra",1,1,"15867144",2005,"Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra.","15867144","Diethylstilbestrol","Urethra",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",0,1,"12611468",2002,"Environmental estrogens: roles in male reproductive tract problems and in breast cancer.","12611468","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"14781",1977,"Induction of urogenital anomalies and some tumors in the progeny of mice receiving diethylstilbestrol during pregnancy.","14781","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,0,"15856964",2005,"Pregnant \"DES daughters\" and their offspring.","15856964","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"19689815",2009,"Urogenital abnormalities in men exposed to diethylstilbestrol in utero: a cohort study.","19689815","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"376358",1979,"Fertility of the diethylstilbestrol-exposed offspring.","376358","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"398263",1979,"The effects of exogenous female hormones on the fetus.","398263","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"454458",1979,"Teratogenesis and carcinogenesis in rat offspring after transplacental and transmammary exposure to diethylstilbestrol.","454458","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",0,1,"4979275",1969,"[Action of diethylstilbestrol on the hybrid from the crossBarbariedrake x Khaki Campbellduck].","4979275","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"6502859",1984,"Males exposed in utero to diethylstilbestrol.","6502859","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"6645389",1983,"Radiologic diagnosis of diethylstilbestrol induced teratogenesis in rats.","6645389","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,0,"6772904",1980,"Carcinogenic and teratogenic activities of diethylstilbestrol in mice.","6772904","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"7035598",1981,"Randomised trial of high doses of stilboestrol and ethisterone therapy in pregnancy: long-term follow-up of the children.","7035598","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,0,"7455920",1980,"Reproductive tract anomalies in mice after prenatal exposure to DES.","7455920","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"7717601",1995,"Diethylstilbestrol revisited: a review of the long-term health effects.","7717601","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"846001",1977,"Prenatal exposure to diethylstilbestrol in mice: toxicological studies.","846001","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
["Diethylstilbestrol","Urogenital Abnormalities",1,1,"972792",1976,"Urogenital tract abnormalities in sons of women treated with diethylstilbestrol.","972792","Diethylstilbestrol","Urogenital Abnormalities",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1668,I1668)","v":"Diethylstilbestrol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1668,J1668)","v":"Vas Deferens"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1668,H1668)","v":"1121332"},1975,"Effects of diethylstilbestrol and testosterone propionate implanted in the hypothalamus on spermatogenesis in rats.","1121332","Diethylstilbestrol","Vas Deferens",1,1,1]
["Diethylstilbestrol","Vas Deferens",0,1,"12446607",2002,"Induction of reproductive tract developmental abnormalities in the male rat by lowering androgen production or action in combination with a low dose of diethylstilbestrol: evidence for importance of the androgen-estrogen balance.","12446607","Diethylstilbestrol","Vas Deferens",1,1,1]
["Diethylstilbestrol","Vas Deferens",0,1,"15855622",2005,"Neonatal treatment of rats with diethylstilboestrol (DES) induces stromal-epithelial abnormalities of the vas deferens and cauda epididymis in adulthood following delayed basal cell development.","15855622","Diethylstilbestrol","Vas Deferens",1,1,1]
["Diethylstilbestrol","Vas Deferens",1,1,"8274821",1993,"Effect of testosterone on diethylstilbestrol toxicity and comparison to a recovery study in the rat epididymis and vas deferens.","8274821","Diethylstilbestrol","Vas Deferens",1,1,1]
["Dimethoate","Epididymis",1,1,"1764985",1991,"Influence of dimethoate on testicular and epididymal organs, testosterone plasma level and their tissue residues in rats.","1764985","Dimethoate","Epididymis",1,1,1]
["Dimethoate","Epididymis",1,1,"19726577",2009,"Early-life exposure to dimethoate-induced reproductive toxicity: evaluation of effects on pituitary-testicular axis of mice.","19726577","Dimethoate","Epididymis",1,1,1]
["Dimethoate","Genitalia, Male",1,1,"20500747",2010,"Comparative effects of dimethoate and deltamethrin on reproductive system in male mice.","20500747","Dimethoate","Genitalia, Male",1,1,1]
["Dimethoate","Sperm Count",1,1,"17234381",2007,"Assessment of reproductive toxicity of orally administered technical dimethoate in male mice.","17234381","Dimethoate","Sperm Count",1,1,1]
["Dimethoate","Sperm Count",1,1,"19726577",2009,"Early-life exposure to dimethoate-induced reproductive toxicity: evaluation of effects on pituitary-testicular axis of mice.","19726577","Dimethoate","Sperm Count",1,1,1]
["Dimethoate","Sperm Count",1,1,"22177304",2011,"[Synergistic effect of dichlorvos, dimethoate and malathion mixture on reproduction toxicity in male mice].","22177304","Dimethoate","Sperm Count",1,1,1]
["Dimethoate","Sperm Motility",1,1,"17234381",2007,"Assessment of reproductive toxicity of orally administered technical dimethoate in male mice.","17234381","Dimethoate","Sperm Motility",1,1,1]
["Dimethoate","Sperm Motility",1,1,"21806655",2012,"Antioxidant supplementations in vitro improve rat sperm parameters and enhance antioxidant enzyme activities against dimethoate-induced sperm damages.","21806655","Dimethoate","Sperm Motility",1,1,1]
["Dimethoate","Sperm Motility",1,1,"22077240",2012,"Embryonic exposure to dimethoate and/or deltamethrin impairs sexual development and programs reproductive success in adult male offspring mice.","22077240","Dimethoate","Sperm Motility",1,1,1]
["Dimethoate","Sperm Motility",1,1,"22177304",2011,"[Synergistic effect of dichlorvos, dimethoate and malathion mixture on reproduction toxicity in male mice].","22177304","Dimethoate","Sperm Motility",1,1,1]
["Dimethoate","Spermatogonia",0,1,"6828067",1983,"Genotoxicity of an organophosphorus insecticide, dimethoate, in the mouse.","6828067","Dimethoate","Spermatogonia",1,1,1]
["Dimethoate","Spermatozoa",1,1,"17234381",2007,"Assessment of reproductive toxicity of orally administered technical dimethoate in male mice.","17234381","Dimethoate","Spermatozoa",1,1,1]
["Dimethoate","Spermatozoa",1,1,"1764985",1991,"Influence of dimethoate on testicular and epididymal organs, testosterone plasma level and their tissue residues in rats.","1764985","Dimethoate","Spermatozoa",1,1,1]
["Dimethoate","Spermatozoa",1,1,"20500747",2010,"Comparative effects of dimethoate and deltamethrin on reproductive system in male mice.","20500747","Dimethoate","Spermatozoa",1,1,1]
["Dimethoate","Spermatozoa",1,1,"21806655",2012,"Antioxidant supplementations in vitro improve rat sperm parameters and enhance antioxidant enzyme activities against dimethoate-induced sperm damages.","21806655","Dimethoate","Spermatozoa",1,1,1]
["Dimethoate","Spermatozoa",1,1,"22177304",2011,"[Synergistic effect of dichlorvos, dimethoate and malathion mixture on reproduction toxicity in male mice].","22177304","Dimethoate","Spermatozoa",1,1,1]
["Dimethoate","Spermatozoa",1,1,"3403918",1988,"Effect of organophosphorus (dimethoate) and pyrethroid (deltamethrin) pesticides on semen characteristics in rabbits.","3403918","Dimethoate","Spermatozoa",1,1,1]
["Dimethoate","Spermatozoa",1,1,"7679190",1993,"Vitamin C-mediated minimisation of Rogor-induced genotoxicity.","7679190","Dimethoate","Spermatozoa",1,1,1]
["Dimethoate","Testis",1,1,"17234381",2007,"Assessment of reproductive toxicity of orally administered technical dimethoate in male mice.","17234381","Dimethoate","Testis",1,1,1]
["Dimethoate","Testis",1,1,"1764985",1991,"Influence of dimethoate on testicular and epididymal organs, testosterone plasma level and their tissue residues in rats.","1764985","Dimethoate","Testis",1,1,1]
["Dimethoate","Testis",1,1,"19726577",2009,"Early-life exposure to dimethoate-induced reproductive toxicity: evaluation of effects on pituitary-testicular axis of mice.","19726577","Dimethoate","Testis",1,1,1]
["dimethyl 2,3,5,6-tetrachloroterephthalate","Testis",1,1,"7286655",1981,"[Effect of the herbicide Dacthal on animal gonads].","7286655","dimethyl 2,3,5,6-tetrachloroterephthalate","Testis",1,null,1]
["Dimethylformamide","Epididymis",0,1,"24412395",2014,"Cryopreservation of epididymal stallion sperm.","24412395","Dimethylformamide","Epididymis",1,null,1]
["Dimethylformamide","Epididymis",1,1,"9114337",1997,"Reproductive toxicology. N,N-dimethylformamide.","9114337","Dimethylformamide","Epididymis",1,null,1]
["Dimethylformamide","Sperm Count",0,1,"11469548",2001,"DMF effects on frozen gander semen.","11469548","Dimethylformamide","Sperm Count",1,null,1]
["Dimethylformamide","Sperm Motility",0,1,"11469548",2001,"DMF effects on frozen gander semen.","11469548","Dimethylformamide","Sperm Motility",1,null,1]
["Dimethylformamide","Sperm Motility",0,1,"21535236",2011,"Extenders containing dimethylformamide associated or not with glycerol are ineffective for ovine sperm cryopreservation.","21535236","Dimethylformamide","Sperm Motility",1,null,1]
["Dimethylformamide","Sperm Motility",0,1,"22384798",2012,"Dimethylformamide improves the in vitro characteristics of thawed stallion spermatozoa reducing sublethal damage.","22384798","Dimethylformamide","Sperm Motility",1,null,1]
["Dimethylformamide","Sperm Motility",0,1,"24412395",2014,"Cryopreservation of epididymal stallion sperm.","24412395","Dimethylformamide","Sperm Motility",1,null,1]
["Dimethylformamide","Spermatozoa",0,1,"11469548",2001,"DMF effects on frozen gander semen.","11469548","Dimethylformamide","Spermatozoa",1,null,1]
["Dimethylformamide","Spermatozoa",0,1,"19019075",2010,"Glycerol, methyl-formamide and dimethyl-formamide in canine semen cryopreservation.","19019075","Dimethylformamide","Spermatozoa",1,null,1]
["Dimethylformamide","Spermatozoa",0,1,"19541362",2009,"Dimethylformamide is no better than glycerol for cryopreservation of canine semen.","19541362","Dimethylformamide","Spermatozoa",1,null,1]
["Dimethylformamide","Spermatozoa",0,1,"21535236",2011,"Extenders containing dimethylformamide associated or not with glycerol are ineffective for ovine sperm cryopreservation.","21535236","Dimethylformamide","Spermatozoa",1,null,1]
["Dimethylformamide","Spermatozoa",0,1,"22384798",2012,"Dimethylformamide improves the in vitro characteristics of thawed stallion spermatozoa reducing sublethal damage.","22384798","Dimethylformamide","Spermatozoa",1,null,1]
["Dimethylformamide","Spermatozoa",0,1,"23453787",2013,"Dimethyl formamide improves the postthaw characteristics of sex-sorted and nonsorted stallion sperm.","23453787","Dimethylformamide","Spermatozoa",1,null,1]
["Dimethylformamide","Spermatozoa",0,1,"24412395",2014,"Cryopreservation of epididymal stallion sperm.","24412395","Dimethylformamide","Spermatozoa",1,null,1]
["Dimethylformamide","Spermatozoa",0,1,"6066500",1967,"The toxicity of various non-electrolytes to human spermatozoa and their protective effects during freezing.","6066500","Dimethylformamide","Spermatozoa",1,null,1]
["Dimethylformamide","Spermatozoa",1,1,"6344335",1983,"Lack of mutagenic activity of dimethylformamide.","6344335","Dimethylformamide","Spermatozoa",1,null,1]
["Dimethylformamide","Testis",1,1,"9114337",1997,"Reproductive toxicology. N,N-dimethylformamide.","9114337","Dimethylformamide","Testis",1,null,1]
["di-n-hexyl phthalate","Epididymis",1,1,"19577633",2009,"Effects of in utero exposure to di-n-hexyl phthalate on the reproductive development of the male rat.","19577633","di-n-hexyl phthalate","Epididymis",1,1,1]
["di-n-hexyl phthalate","Epididymis",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","di-n-hexyl phthalate","Epididymis",1,1,1]
["di-n-hexyl phthalate","Genitalia, Male",1,1,"19577633",2009,"Effects of in utero exposure to di-n-hexyl phthalate on the reproductive development of the male rat.","19577633","di-n-hexyl phthalate","Genitalia, Male",1,1,1]
["di-n-hexyl phthalate","Prostate",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","di-n-hexyl phthalate","Prostate",1,1,1]
["di-n-hexyl phthalate","Prostate",1,1,"9114310",1997,"Reproductive toxicology. Di-n-hexylphthalate.","9114310","di-n-hexyl phthalate","Prostate",1,1,1]
["di-n-hexyl phthalate","Sertoli Cells",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","di-n-hexyl phthalate","Sertoli Cells",1,1,1]
["di-n-hexyl phthalate","Sperm Count",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","di-n-hexyl phthalate","Sperm Count",1,1,1]
["di-n-hexyl phthalate","Sperm Count",1,1,"9114310",1997,"Reproductive toxicology. Di-n-hexylphthalate.","9114310","di-n-hexyl phthalate","Sperm Count",1,1,1]
["di-n-hexyl phthalate","Sperm Head",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","di-n-hexyl phthalate","Sperm Head",1,1,1]
["di-n-hexyl phthalate","Sperm Motility",1,1,"9114310",1997,"Reproductive toxicology. Di-n-hexylphthalate.","9114310","di-n-hexyl phthalate","Sperm Motility",1,1,1]
["di-n-hexyl phthalate","Testis",1,1,"19577633",2009,"Effects of in utero exposure to di-n-hexyl phthalate on the reproductive development of the male rat.","19577633","di-n-hexyl phthalate","Testis",1,1,1]
["di-n-hexyl phthalate","Testis",1,1,"23022015",2013,"Developmental effects of prenatal di-n-hexyl phthalate and dicyclohexyl phthalate exposure on reproductive tract of male rats: Postnatal outcomes.","23022015","di-n-hexyl phthalate","Testis",1,1,1]
["di-n-hexyl phthalate","Testis",1,1,"23754470",2013,"Dose-dependent alterations in gene expression and testosterone production in fetal rat testis after exposure to di-n-hexyl phthalate.","23754470","di-n-hexyl phthalate","Testis",1,1,1]
["di-n-hexyl phthalate","Testis",1,1,"23836838",2014,"In utero exposure to dicyclohexyl and di-n-hexyl phthalate possess genotoxic effects on testicular cells of male rats after birth in the comet and TUNEL assays.","23836838","di-n-hexyl phthalate","Testis",1,1,1]
["di-n-hexyl phthalate","Testis",1,1,"9114310",1997,"Reproductive toxicology. Di-n-hexylphthalate.","9114310","di-n-hexyl phthalate","Testis",1,1,1]
["di-n-pentyl phthalate","Epididymis",1,1,"9114312",1997,"Reproductive toxicology. Di-n-pentylphthalate.","9114312","di-n-pentyl phthalate","Epididymis",1,1,1]
["di-n-pentyl phthalate","Seminal Vesicles",1,1,"9114312",1997,"Reproductive toxicology. Di-n-pentylphthalate.","9114312","di-n-pentyl phthalate","Seminal Vesicles",1,1,1]
["di-n-pentyl phthalate","Sertoli Cells",1,1,"17409460",2007,"Acute adverse effects of the indenopyridine CDB-4022 on the ultrastructure of sertoli cells, spermatocytes, and spermatids in rat testes: comparison to the known sertoli cell toxicant Di-n-pentylphthalate (DPP).","17409460","di-n-pentyl phthalate","Sertoli Cells",1,1,1]
["di-n-pentyl phthalate","Sertoli Cells",1,1,"3595805",1987,"The ultrastructural effects of di-n-pentyl phthalate on the testis of the mature rat.","3595805","di-n-pentyl phthalate","Sertoli Cells",1,1,1]
["di-n-pentyl phthalate","Sperm Count",1,1,"9114312",1997,"Reproductive toxicology. Di-n-pentylphthalate.","9114312","di-n-pentyl phthalate","Sperm Count",1,1,1]
["di-n-pentyl phthalate","Spermatids",1,1,"17409460",2007,"Acute adverse effects of the indenopyridine CDB-4022 on the ultrastructure of sertoli cells, spermatocytes, and spermatids in rat testes: comparison to the known sertoli cell toxicant Di-n-pentylphthalate (DPP).","17409460","di-n-pentyl phthalate","Spermatids",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1732,I1732)","v":"di-n-pentyl phthalate"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1732,J1732)","v":"Spermatocytes"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1732,H1732)","v":"17409460"},2007,"Acute adverse effects of the indenopyridine CDB-4022 on the ultrastructure of sertoli cells, spermatocytes, and spermatids in rat testes: comparison to the known sertoli cell toxicant Di-n-pentylphthalate (DPP).","17409460","di-n-pentyl phthalate","Spermatocytes",1,1,1]
["di-n-pentyl phthalate","Spermatozoa",1,1,"3220221",1988,"Comparison of changes in serum androgen binding protein with germinal epithelial damage and infertility induced by di-n-pentyl phthalate.","3220221","di-n-pentyl phthalate","Spermatozoa",1,1,1]
["di-n-pentyl phthalate","Spermatozoa",1,1,"3595805",1987,"The ultrastructural effects of di-n-pentyl phthalate on the testis of the mature rat.","3595805","di-n-pentyl phthalate","Spermatozoa",1,1,1]
["di-n-pentyl phthalate","Testis",1,1,"17409460",2007,"Acute adverse effects of the indenopyridine CDB-4022 on the ultrastructure of sertoli cells, spermatocytes, and spermatids in rat testes: comparison to the known sertoli cell toxicant Di-n-pentylphthalate (DPP).","17409460","di-n-pentyl phthalate","Testis",1,1,1]
["di-n-pentyl phthalate","Testis",1,1,"21177253",2011,"Dipentyl phthalate dosing during sexual differentiation disrupts fetal testis function and postnatal development of the male Sprague-Dawley rat with greater relative potency than other phthalates.","21177253","di-n-pentyl phthalate","Testis",1,1,1]
["di-n-pentyl phthalate","Testis",1,1,"3220221",1988,"Comparison of changes in serum androgen binding protein with germinal epithelial damage and infertility induced by di-n-pentyl phthalate.","3220221","di-n-pentyl phthalate","Testis",1,1,1]
["di-n-pentyl phthalate","Testis",1,1,"3595805",1987,"The ultrastructural effects of di-n-pentyl phthalate on the testis of the mature rat.","3595805","di-n-pentyl phthalate","Testis",1,1,1]
["di-n-pentyl phthalate","Testis",1,1,"9114312",1997,"Reproductive toxicology. Di-n-pentylphthalate.","9114312","di-n-pentyl phthalate","Testis",1,1,1]
["diphenylguanidine","Spermatozoa",1,1,"1729764",1992,"Effect of oral administration of 1,3-diphenylguanidine on sperm morphology and male fertility in mice.","1729764","diphenylguanidine","Spermatozoa",1,null,1]
["diphenylguanidine","Spermatozoa",1,1,"6620417",1983,"Reproductive toxicology of 1,3-diphenylguanidine: analysis of induced sperm abnormalities in mice and hamsters and reproductive consequences in mice.","6620417","diphenylguanidine","Spermatozoa",1,null,1]
["diphenylguanidine","Testis",1,1,"1729764",1992,"Effect of oral administration of 1,3-diphenylguanidine on sperm morphology and male fertility in mice.","1729764","diphenylguanidine","Testis",1,null,1]
["diphenylguanidine","Testis",1,1,"6620417",1983,"Reproductive toxicology of 1,3-diphenylguanidine: analysis of induced sperm abnormalities in mice and hamsters and reproductive consequences in mice.","6620417","diphenylguanidine","Testis",1,null,1]
["Endosulfan","Epididymis",1,1,"12755467",2003,"Pre and postnatal exposure to endosulfan in Wistar rats.","12755467","Endosulfan","Epididymis",1,null,1]
["Endosulfan","Leydig Cells",1,1,"16002328",2005,"5-Aminosalicylic acid reverses endosulfan-induced testicular toxicity in male rats.","16002328","Endosulfan","Leydig Cells",1,null,1]
["Endosulfan","Prostate",1,1,"12755467",2003,"Pre and postnatal exposure to endosulfan in Wistar rats.","12755467","Endosulfan","Prostate",1,null,1]
["Endosulfan","Seminal Vesicles",1,1,"12755467",2003,"Pre and postnatal exposure to endosulfan in Wistar rats.","12755467","Endosulfan","Seminal Vesicles",1,null,1]
["Endosulfan","Sertoli Cells",1,1,"10453913",1999,"Cytotoxic effect of endosulfan on rat Sertoli-germ cell coculture.","10453913","Endosulfan","Sertoli Cells",1,null,1]
["Endosulfan","Sperm Count",1,1,"10523873",1999,"Reproductive effects of endosulfan on male offspring of rats exposed during pregnancy and lactation.","10523873","Endosulfan","Sperm Count",1,null,1]
["Endosulfan","Sperm Count",1,1,"12755467",2003,"Pre and postnatal exposure to endosulfan in Wistar rats.","12755467","Endosulfan","Sperm Count",1,null,1]
["Endosulfan","Sperm Count",1,1,"16002328",2005,"5-Aminosalicylic acid reverses endosulfan-induced testicular toxicity in male rats.","16002328","Endosulfan","Sperm Count",1,null,1]
["Endosulfan","Sperm Count",1,1,"16440852",2005,"L-ascorbic acid ameliorates postnatal endosulfan induced testicular damage in rats.","16440852","Endosulfan","Sperm Count",1,null,1]
["Endosulfan","Sperm Count",1,1,"17613005",2007,"Protective role of ascorbic acid on subacute sperm toxicity in male New Zealand white rabbits treated with endosulfan.","17613005","Endosulfan","Sperm Count",1,null,1]
["Endosulfan","Sperm Count",1,1,"8588293",1995,"Endosulfan-induced biochemical changes in the testis of rats.","8588293","Endosulfan","Sperm Count",1,null,1]
["Endosulfan","Sperm Count",1,1,"8952929",1997,"Effect of endosulfan on the testis of growing rats.","8952929","Endosulfan","Sperm Count",1,null,1]
["Endosulfan","Sperm Head",1,1,"17613005",2007,"Protective role of ascorbic acid on subacute sperm toxicity in male New Zealand white rabbits treated with endosulfan.","17613005","Endosulfan","Sperm Head",1,null,1]
["Endosulfan","Sperm Motility",1,1,"16440852",2005,"L-ascorbic acid ameliorates postnatal endosulfan induced testicular damage in rats.","16440852","Endosulfan","Sperm Motility",1,null,1]
["Endosulfan","Sperm Motility",1,1,"17613005",2007,"Protective role of ascorbic acid on subacute sperm toxicity in male New Zealand white rabbits treated with endosulfan.","17613005","Endosulfan","Sperm Motility",1,null,1]
["Endosulfan","Sperm Motility",1,1,"21241381",2011,"Effects of heavy metals and pesticides on buffalo (Bubalus bubalis) spermatozoa functions in vitro.","21241381","Endosulfan","Sperm Motility",1,null,1]
["Endosulfan","Sperm Motility",1,1,"8588293",1995,"Endosulfan-induced biochemical changes in the testis of rats.","8588293","Endosulfan","Sperm Motility",1,null,1]
["Endosulfan","Sperm Tail",1,1,"17613005",2007,"Protective role of ascorbic acid on subacute sperm toxicity in male New Zealand white rabbits treated with endosulfan.","17613005","Endosulfan","Sperm Tail",1,null,1]
["Endosulfan","Spermatids",1,1,"8952929",1997,"Effect of endosulfan on the testis of growing rats.","8952929","Endosulfan","Spermatids",1,null,1]
["Endosulfan","Spermatocytes",1,1,"10453913",1999,"Cytotoxic effect of endosulfan on rat Sertoli-germ cell coculture.","10453913","Endosulfan","Spermatocytes",1,null,1]
["Endosulfan","Spermatocytes",1,1,"16485171",2006,"The effects of endosulfan on the testes of bluegill fish, Lepomis macrochirus: a histopathological study.","16485171","Endosulfan","Spermatocytes",1,null,1]
["Endosulfan","Spermatocytes",1,1,"18613510",2008,"[Induced apoptosis and mechanism of endosulfan in mouse germ cells].","18613510","Endosulfan","Spermatocytes",1,null,1]
["Endosulfan","Spermatocytes",1,1,"22307005",2012,"Endosulfan and flutamide impair testicular development in the juvenile Asian catfish, Clarias batrachus.","22307005","Endosulfan","Spermatocytes",1,null,1]
["Endosulfan","Spermatogenesis",1,1,"12545360",2003,"Reproductive toxicity of endosulfan in male albino rats.","12545360","Endosulfan","Spermatogenesis",1,null,1]
["Endosulfan","Spermatogenesis",1,1,"16002328",2005,"5-Aminosalicylic acid reverses endosulfan-induced testicular toxicity in male rats.","16002328","Endosulfan","Spermatogenesis",1,null,1]
["Endosulfan","Spermatogenesis",1,1,"8588293",1995,"Endosulfan-induced biochemical changes in the testis of rats.","8588293","Endosulfan","Spermatogenesis",1,null,1]
["Endosulfan","Spermatogenesis",1,1,"8952929",1997,"Effect of endosulfan on the testis of growing rats.","8952929","Endosulfan","Spermatogenesis",1,null,1]
["Endosulfan","Spermatogonia",1,1,"10453913",1999,"Cytotoxic effect of endosulfan on rat Sertoli-germ cell coculture.","10453913","Endosulfan","Spermatogonia",1,null,1]
["Endosulfan","Spermatogonia",1,1,"16485171",2006,"The effects of endosulfan on the testes of bluegill fish, Lepomis macrochirus: a histopathological study.","16485171","Endosulfan","Spermatogonia",1,null,1]
["Endosulfan","Spermatogonia",1,1,"22307005",2012,"Endosulfan and flutamide impair testicular development in the juvenile Asian catfish, Clarias batrachus.","22307005","Endosulfan","Spermatogonia",1,null,1]
["Endosulfan","Spermatogonia",1,1,"749981",1978,"Endosulfan: lack of cytogenetic effects in male rats.","749981","Endosulfan","Spermatogonia",1,null,1]
["Endosulfan","Spermatozoa",1,1,"10523873",1999,"Reproductive effects of endosulfan on male offspring of rats exposed during pregnancy and lactation.","10523873","Endosulfan","Spermatozoa",1,null,1]
["Endosulfan","Spermatozoa",1,1,"12755467",2003,"Pre and postnatal exposure to endosulfan in Wistar rats.","12755467","Endosulfan","Spermatozoa",1,null,1]
["Endosulfan","Spermatozoa",1,1,"16002328",2005,"5-Aminosalicylic acid reverses endosulfan-induced testicular toxicity in male rats.","16002328","Endosulfan","Spermatozoa",1,null,1]
["Endosulfan","Spermatozoa",1,1,"16440852",2005,"L-ascorbic acid ameliorates postnatal endosulfan induced testicular damage in rats.","16440852","Endosulfan","Spermatozoa",1,null,1]
["Endosulfan","Spermatozoa",1,1,"17613005",2007,"Protective role of ascorbic acid on subacute sperm toxicity in male New Zealand white rabbits treated with endosulfan.","17613005","Endosulfan","Spermatozoa",1,null,1]
["Endosulfan","Spermatozoa",1,1,"19243027",2009,"An assessment of the developmental, reproductive, and neurotoxicity of endosulfan.","19243027","Endosulfan","Spermatozoa",1,null,1]
["Endosulfan","Spermatozoa",1,1,"21241381",2011,"Effects of heavy metals and pesticides on buffalo (Bubalus bubalis) spermatozoa functions in vitro.","21241381","Endosulfan","Spermatozoa",1,null,1]
["Endosulfan","Spermatozoa",1,1,"22705290",2012,"Mitochondrial energy metabolism dysfunction involved in reproductive toxicity of mice caused by endosulfan and protective effects of vitamin E.","22705290","Endosulfan","Spermatozoa",1,null,1]
["Endosulfan","Spermatozoa",1,1,"2392119",1990,"Studies on the genotoxicity of endosulfan, an organochlorine insecticide, in mammalian germ cells.","2392119","Endosulfan","Spermatozoa",1,null,1]
["Endosulfan","Spermatozoa",1,1,"8952929",1997,"Effect of endosulfan on the testis of growing rats.","8952929","Endosulfan","Spermatozoa",1,null,1]
["Endosulfan","Testis",1,1,"10523873",1999,"Reproductive effects of endosulfan on male offspring of rats exposed during pregnancy and lactation.","10523873","Endosulfan","Testis",1,null,1]
["Endosulfan","Testis",1,1,"12545360",2003,"Reproductive toxicity of endosulfan in male albino rats.","12545360","Endosulfan","Testis",1,null,1]
["Endosulfan","Testis",1,1,"12755467",2003,"Pre and postnatal exposure to endosulfan in Wistar rats.","12755467","Endosulfan","Testis",1,null,1]
["Endosulfan","Testis",1,1,"16002328",2005,"5-Aminosalicylic acid reverses endosulfan-induced testicular toxicity in male rats.","16002328","Endosulfan","Testis",1,null,1]
["Endosulfan","Testis",1,1,"16440852",2005,"L-ascorbic acid ameliorates postnatal endosulfan induced testicular damage in rats.","16440852","Endosulfan","Testis",1,null,1]
["Endosulfan","Testis",1,1,"16485171",2006,"The effects of endosulfan on the testes of bluegill fish, Lepomis macrochirus: a histopathological study.","16485171","Endosulfan","Testis",1,null,1]
["Endosulfan","Testis",1,1,"21842492",2011,"Effects of ?-endosulfan on the growth and reproduction of zebrafish (Danio rerio).","21842492","Endosulfan","Testis",1,null,1]
["Endosulfan","Testis",1,1,"22307005",2012,"Endosulfan and flutamide impair testicular development in the juvenile Asian catfish, Clarias batrachus.","22307005","Endosulfan","Testis",1,null,1]
["Endosulfan","Testis",1,1,"22705290",2012,"Mitochondrial energy metabolism dysfunction involved in reproductive toxicity of mice caused by endosulfan and protective effects of vitamin E.","22705290","Endosulfan","Testis",1,null,1]
["Endosulfan","Testis",1,1,"23225381",2014,"Effect of commercial grade endosulfan on growth and reproduction of the fighting fish Betta splendens.","23225381","Endosulfan","Testis",1,null,1]
["Endosulfan","Testis",1,1,"8588293",1995,"Endosulfan-induced biochemical changes in the testis of rats.","8588293","Endosulfan","Testis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1796,I1796)","v":"Endosulfan"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1796,J1796)","v":"Testis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1796,H1796)","v":"8952929"},1997,"Effect of endosulfan on the testis of growing rats.","8952929","Endosulfan","Testis",1,null,1]
["Estradiol","46, XX Disorders of Sex Development",0,0,"22713853",2012,"17?-Estradiol is critical for the preovulatory induction of prostaglandin E(2) synthesis in mice.","22713853","Estradiol","46, XX Disorders of Sex Development",1,null,1]
["Estradiol","46, XX Disorders of Sex Development",0,0,"22964562",2012,"Impact of estrogen replacement throughout childhood on growth, pituitary-gonadal axis and bone in a 46,XX patient with CYP19A1 deficiency.","22964562","Estradiol","46, XX Disorders of Sex Development",1,null,1]
["Estradiol","46, XY Disorders of Sex Development",0,0,"23466679",2013,"Rare missense P450c17 (CYP17A1) mutation in exon 1 as a cause of 46,XY disorder of sexual development: implications of breast tissue 'unresponsiveness' despite adequate estradiol substitution.","23466679","Estradiol","46, XY Disorders of Sex Development",1,null,1]
["Estradiol","Acrosome",0,1,"20562298",2010,"Suppression of progesterone-enhanced hyperactivation in hamster spermatozoa by estrogen.","20562298","Estradiol","Acrosome",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,1,"10983628",2000,"Euthyroid hyperthyrotropinemia secondary to hyperestrogenemia in a male with congenital adrenal hyperplasia.","10983628","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,0,"2493041",1989,"In vitro fertilization and primary embryonic cleavage are possible in 17 alpha-hydroxylase deficiency despite extremely low intrafollicular 17 beta-estradiol.","2493041","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,1,"4289300",1967,"Oestrogens in congenital adrenal hyperplasia.","4289300","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,1,"4371221",1974,"Serum 17-alpha-hydroxyprogesterone, progesterone, estradiol, and testosterone in the diagnosis and management of congenital adrenal hyperplasia.","4371221","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,1,"4795966",1973,"Plasma estrogens in childhood and puberty under physiologic and pathologic conditions.","4795966","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,1,"5688816",1968,"Production of congenital adrenocortical hyperplasia in rats by estradiol-17-beta and inhibition of 3-beta-hydroxysteroid dehydrogenase.","5688816","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,1,"5843262",1965,"Biosynthesis of steroids in various tissues related to feminizing syndromes.","5843262","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,1,"5944308",1966,"[Quantitative determination of estrone and estradiol-17-beta in healthy women and men and in pathological conditions].","5944308","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,0,"7438482",1980,"Oestrogen dynamics in adrenal venous effluents in congenital virilizing adrenal hyperplasia.","7438482","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,0,"8530686",1995,"Induction of artificial endometrial cycles with oestradiol implants and injectable progesterone: establishment of a viable pregnancy in a woman with 17-alpha-hydroxylase deficiency.","8530686","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,0,"8943512",1996,"Ovarian hyperstimulation syndrome with low oestradiol in non-classical 17 alpha-hydroxylase, 17,20-lyase deficiency: what is the role of oestrogens?","8943512","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenal Hyperplasia, Congenital",0,0,"8957277",1996,"Substitution with testosterone as aromatizable substrate for induction of follicular maturation, estradiol production and ovulation in a patient with 17 alpha-hydroxylase deficiency.","8957277","Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Estradiol","Adrenogenital Syndrome",0,0,"13993186",1963,"[Diagnostic peculiarities of steroid hormone analysis in specific forms of the adrenogenital syndrome].","13993186","Estradiol","Adrenogenital Syndrome",1,null,1]
["Estradiol","Adrenogenital Syndrome",0,0,"14209291",1964,"THE FEMINIZING SYNDROME IN MALE SUBJECTS WITH ADRENOCORTICAL NEOPLASMS.","14209291","Estradiol","Adrenogenital Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"1626917",1992,"Incomplete testicular feminization syndrome: studies of 17 beta-oestradiol-binding activity and aromatase activity in cultured genital fibroblasts showing impaired dihydrotestosterone-binding.","1626917","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"17011702",2007,"A naturally occurring mutation in the human androgen receptor of a subject with complete androgen insensitivity confers binding and transactivation by estradiol.","17011702","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"17486276",2007,"Expression of Nkx3.1 enhances 17beta-estradiol anti-tumor action in PC3 human prostate cancer cells.","17486276","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"179788",1976,"Androgen and estrogen receptors in brain cytosol from male, female, and testicular feminized (tfm/y hermaphrodite) mice.","179788","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"20353424",2010,"Tissue changes in senescent gerbil prostate after hormone deprivation leads to acquisition of androgen insensitivity.","20353424","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"31863",1978,"Effect of the mouse mutants testicular feminization and sex reversal on hormone-mediated induction and repression of enzymes.","31863","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"4259253",1972,"Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.","4259253","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"4416135",1974,"The control of gonadotropin secretion in complete testicular feminization.","4416135","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"4479558",1974,"Testosterone and oestradiol in dogs with testicular tumours.","4479558","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"4799006",1973,"[Induction of estrogen production in the embryonic chicken testicle by dihydrotestosterone].","4799006","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,0,"5769946",1969,"[Estrone and estradiol secretion by embryonic gonads of birds].","5769946","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"6416071",1983,"Gonadotropins and gonadal steroids in androgen insensitivity (testicular feminization) syndrome: effects of castration and sex steroid administration.","6416071","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"6421963",1984,"Danazol suppression of gonadal estradiol-17 beta secretion--report of two sibling cases with a complete form of testicular feminization on gonadal ultrastructure and endocrine status.","6421963","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"6792578",1981,"Effect of estrogens and progesterone on gonadotropin and prolactin release in a patient with androgen insensitivity.","6792578","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"6800258",1982,"Effect of danazol on gonadal steroidogenesis in patients with a complete form of testicular feminization.","6800258","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"680194",1978,"Preliminary studies on streoid-binding proteins in human testes of testicular feminization syndrome.","680194","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"7645764",1995,"Action of testosterone on the estradiol-induced feminization of the male chick embryo.","7645764","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,1,"7734625",1995,"Eysenck's personality dimensions and sex steroids in male abstinent alcoholics and nonalcoholics: an exploratory study.","7734625","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Androgen-Insensitivity Syndrome",0,0,"831170",1977,"Induction of an LH surge with estradiol benzoate in a patient with incomplete testicular feminization syndrome.","831170","Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Estradiol","Blood-Testis Barrier",0,1,"18292837",2007,"During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.","18292837","Estradiol","Blood-Testis Barrier",1,null,1]
["Estradiol","Bulbourethral Glands",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Estradiol","Bulbourethral Glands",1,null,1]
["Estradiol","Cryptorchidism",1,1,"10926772",2000,"A molecular basis for estrogen-induced cryptorchidism.","10926772","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"11025750",2000,"Elevated placental estradiol: a possible etiological factor of human cryptorchidism.","11025750","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"11025751",2000,"Excess fetal estrogen as an etiological cause of human cryptorchidism.","11025751","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"12443684",2002,"Blood plasma concentrations of oestradiol-17beta, testosterone and testosterone/oestradiol ratio in dogs with neoplastic and degenerative testicular diseases.","12443684","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"12722",1976,"[Effect of neonatal injections of estradiol, testosterone and cryproterone acetate on plasma and testicular testosterone and on the genital system in adult male mice].","12722","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"12931",1977,"Gonadotropin secretion in cryptorchid and castrate rams and the acute effects of exogenous steroid treatment.","12931","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,0,"14245076",1965,"STEROID SYNTHESIS IN THE CRYPTORCHID TESTES OF THREE CASES OF THE \"TESTICULAR FEMINIZATION\" SYNDROME.","14245076","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,0,"14263903",1964,"[EFFECT OF A SINGLE DOSE OF ESTRADIOL BENZOATE ADMINISTERED BEFORE THE 5TH DAY OF LIFE ON THE GENITAL TRACT OF THE RAT].","14263903","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,0,"14289090",1964,"[CONGENITAL CRYPTORCHISM INDUCED BY ESTROGEN INJECTION INTO THE PREGNANT MOUSE].","14289090","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"14715828",2004,"Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: effects of testosterone, alendronate, and estradiol treatment.","14715828","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"15371802",2004,"Reproductive hormone levels in infants with cryptorchidism during postnatal activation of the pituitary-testicular axis.","15371802","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"16873133",2006,"Plasma testosterone and estradiol levels in unilateral cryptorchidism.","16873133","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"17712483",2007,"17beta-estradiol stimulates proliferation of spermatogonia in experimental cryptorchid mice.","17712483","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"18465685",2008,"The effects of cryptorchidism on the regulation of steroidogenesis and gap junctional communication in equine testes.","18465685","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"19037884",2009,"Use of intralesional oestradiol concentration to identify a functional pulmonary metastasis of canine sertoli cell tumour.","19037884","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"19233",1977,"Estradiol binding capacity in the cryptorchid rat testis.","19233","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"1968991",1990,"Peripheral plasma levels of LH, testosterone, and estradiol-17 beta before and after orchiopexy in unilaterally cryptorchid dogs.","1968991","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"21752447",2011,"In vitro effects of estradiol-17?, monobutyl phthalate and mono-(2-ethylhexyl) phthalate on the secretion of testosterone and insulin-like peptide 3 by interstitial cells of scrotal and retained testes in dogs.","21752447","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",1,1,"23469656",2013,"[Establishment of cryptorchid infertile models by postnatal injection of estradiol in mice].","23469656","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"242175",1975,"The effect of artificial cryptorchidism on serum oestrogen and testosterone levels in the adult male rat.","242175","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"2566621",1989,"Improvement of spermatogenesis after treatment with the antiestrogen tamoxifen in a man with the incomplete androgen insensitivity syndrome.","2566621","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"2569957",1989,"Concentrations of oestradiol and testosterone in peripheral and spermatic venous blood of dogs with unilateral cryptorchidism.","2569957","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"2570718",1989,"AVP receptors of mouse Leydig cells are regulated by LH and E2 and influenced by experimental cryptorchidism.","2570718","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"2857482",1985,"Kinetics of the steroidogenic response to single versus repeated doses of human chorionic gonadotropin in boys in prepuberty and early puberty.","2857482","Estradiol","Cryptorchidism",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1860,I1860)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1860,J1860)","v":"Cryptorchidism"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1860,H1860)","v":"2888831"},1987,"Undescended testis and hormone levels in early pregnancy.","2888831","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"2893331",1987,"[The GnRH test reveals changes in readiness of testosterone and estradiol secretion in boys with bilateral cryptorchism].","2893331","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"36274",1979,"Alterations in steroidogenesis and human chorionic gonadotropin binding in the cryptorchid rat testis.","36274","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"4150097",1970,"The effects of steroid and gonadotrophic hormones in vitro on the metabolic activity of normal and cryptorchid rat testicular tissues.","4150097","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"4151680",1974,"Plasma testosterone and estradiol concentration in prepubertal boys with cryptorchidism before and after dexamethasone and after human chorionic gonadotropin administration.","4151680","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",1,1,"4152351",1973,"[Growth and structure of cryptorchid testes in mice born of mothers treated by oestradiol during pregnancy (author's transl)].","4152351","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"4153231",1974,"[Plasma levels of testosterone and estradiol in prepuberal children with cryptorchism and anorchia before and after administration of HCG].","4153231","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"4153922",1974,"[Endocrine function of the testis in 125 cases of cryptorchism].","4153922","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",1,1,"4387385",1968,"[Genital malformations induced in adult mice by a prenatal estrogenic action. I. The male (male pseudo-hermaphroditism)].","4387385","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"4389015",1967,"[Stimulation by postnatal estrogen treatment of female genital structures obtained in male adult mice by injection of estradiol in the pregnant mother].","4389015","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"4400631",1972,"The hormonal response to HCG stimulation in male children and adolescents.","4400631","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"4405594",1972,"[Comparative study of changes in gonadotropic cells and testis in male rats treated with estrogens during the neonatal period].","4405594","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"6105952",1980,"Cryptorchid rhesus macaques: long term studies on changes in gonadotropins and gonadal steroids.","6105952","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"6105953",1980,"Influence of bilateral cryptorchidism in the mature rat: alterations in testicular function and serum hormone levels.","6105953","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"6108036",1980,"Decreased testicular response to acute LH-stimulation and increased intratesticular concentration of oestradiol-17 beta in the abdominal testes in cryptorchid rats.","6108036","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"6111879",1980,"Transmission and scanning electron microscopy of epididymis in male mice receiving estrogen during gestation.","6111879","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"6115686",1981,"Cryptorchidism: residual effects on steroid-regulated gonadotropin release in recently castrated rhesus monkeys.","6115686","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"6118000",1980,"[Regulation of testicular function by estradiol. I. Standard of development and variations in the post-cryptorchism estradiol receptor].","6118000","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"7584881",1995,"Bone mass in androgen-insensitivity syndrome: response to hormonal replacement therapy.","7584881","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"8605110",1996,"A case-control study of cryptorchidism and maternal hormone concentrations in early pregnancy.","8605110","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Cryptorchidism",0,1,"8941",1976,"Hypophyso-gonadal function in the cryptorchid child: differences between unilateral and bilateral cryptorchids.","8941","Estradiol","Cryptorchidism",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"10341717",1999,"Evidence of sex reversal in the gonads of chicken embryos after oestrogen treatment as detected by expression of lutropin receptor.","10341717","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"10868483",2000,"Sex steroids relative to alternative mating behaviors in the simultaneous hermaphrodite Serranus subligarius (Perciformes: Serranidae).","10868483","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"10911399",2000,"Induction of gonadal intersex in genotypic male rainbow trout (Oncorhynchus mykiss) embryos following immersion in estradiol-17beta.","10911399","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"11466233",2001,"Estrogen-induced gonadal sex reversal in the tammar wallaby.","11466233","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"11800162",2001,"The influence of estrogen on the developing male marsupial.","11800162","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"122442",1978,"Gynecomastia as a familial incomplete male pseudohermaphroditism type 1: a limited androgen resistance syndrome.","122442","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"12840815",2003,"Degree of sex reversal as related to plasma steroid levels in genetic female chickens (Gallus domesticus) treated with Fadrozole.","12840815","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"14194452",1964,"CLINICAL, HORMONAL AND CYTOGENETIC FINDINGS IN A TRUE HERMAPHRODITE.","14194452","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"14201828",1964,"[THE ENDOCRINE TESTICLE. (RECENT PHYSIOLOGICAL AND PHYSIOPATHOLOGICAL IDEAS)].","14201828","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"14208644",1964,"[BIOLOGIC STUDY OF A CASE OF \"FEMINIZING TESTIS\"].","14208644","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"14245076",1965,"STEROID SYNTHESIS IN THE CRYPTORCHID TESTES OF THREE CASES OF THE \"TESTICULAR FEMINIZATION\" SYNDROME.","14245076","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"14252276",1965,"TRUE HERMAPHRODITISM WITH XX-XY MOSAICISM, PROBABLY DUE TO DOUBLE FERTILIZATION OF THE OVUM.","14252276","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"14290160",1965,"STEROID BIOSYNTHESIS IN VITRO BY FEMINIZING TESTES.","14290160","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"14344569",1965,"[TREATMENT WITH ESTROGENS IN PREGNANCY AND MASCULINIZING GENITAL MALFORMATIONS IN A NEWBORN INFANT].","14344569","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",1,1,"16139364",2006,"All ZZ male Xenopus laevis provides a clear sex-reversal test for feminizing endocrine disruptors.","16139364","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"16818259",2006,"Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/feminization hypothesis.","16818259","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"17148408",2006,"Long-term sex reversal by oestradiol in amniotes with heteromorphic sex chromosomes.","17148408","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"17544424",2008,"Effects of larval exposure to estradiol on spermatogenesis and in vitro gonadal steroid secretion in African clawed frogs, Xenopus laevis.","17544424","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"19799515",2009,"Estradiol-17beta treatment induces intersexual gonadal development in the pufferfish, Takifugu rubripes.","19799515","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"2055436",1991,"Estrogen and sex reversal in turtles: a dose-dependent phenomenon.","2055436","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"20601066",2010,"Upregulation of estrogen receptor subtypes and vitellogenin mRNA in cinnamon clownfish Amphiprion melanopus during the sex change process: profiles on effects of 17beta-estradiol.","20601066","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",1,1,"20821545",2010,"Effects of 17 beta-estradiol exposure on Xenopus laevis gonadal histopathology.","20821545","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"2444447",1987,"The modulating effect of estrogens on luteinizing hormone release in complete androgen insensitivity syndrome before and after gonadectomy and cyclic steroid application.","2444447","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"2600902",1989,"Luteinizing hormone response to an oestradiol challenge in 5 intersex pigs possessing ovotestes.","2600902","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"309840",1978,"A histochemical study of the adrenogenital syndrome in frog tadpoles.","309840","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"31863",1978,"Effect of the mouse mutants testicular feminization and sex reversal on hormone-mediated induction and repression of enzymes.","31863","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"3417117",1988,"Sex reversal by estradiol in three reptilian orders.","3417117","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"347778",1977,"[Endocrinological studies in Reifenstein's syndrome].","347778","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"3552919",1987,"Reversal of the LH response to oestrogen administration after orchidectomy in a male subject with the androgen insensitivity syndrome.","3552919","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"3721408",1986,"Female-typical sexual behavior of rhesus and defeminization by androgens given prenatally.","3721408","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"4259253",1972,"Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.","4259253","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"4335778",1972,"Differentiation of male chick oviducts under hormonal stimulation.","4335778","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",1,1,"4387385",1968,"[Genital malformations induced in adult mice by a prenatal estrogenic action. I. The male (male pseudo-hermaphroditism)].","4387385","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"4389015",1967,"[Stimulation by postnatal estrogen treatment of female genital structures obtained in male adult mice by injection of estradiol in the pregnant mother].","4389015","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"4663532",1972,"Effect of sex hormones on development of urogenital system in reptile embryos.","4663532","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"4676748",1972,"[Somatic sexual differentiation of rat fetuses. The action of clomiphene on fetuses whose mothers had been treated with estradiol or testosterone propionate].","4676748","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"489915",1979,"Effects of estrogen on the release of gonadotropins and prolactin in male pseudohermaphrodites.","489915","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"4963604",1967,"[Secretion of estrone and estradiol by the feminized chick-embryo testis].","4963604","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"5067082",1972,"[Sex and age dependent development of activation patterns of steroid hormone metabolism enzymes in rat liver after neonatal interference with sex differentiation].","5067082","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"5470338",1970,"Immuno-electrophoretic study of secretion in cystic oviducts of female and intersexual chicks.","5470338","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"561119",1977,"Hormonal control of sexual attraction in pseudohermaphroditic female dogs.","561119","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"568390",1978,"Production and origin of estrogen in two true hermaphrodites.","568390","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"5901834",1966,"Steroid synthesis in vitro by tumour tissue from a dysgenetic gonad.","5901834","Estradiol","Disorders of Sex Development",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1924,I1924)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1924,J1924)","v":"Disorders of Sex Development"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1924,H1924)","v":"5948902"},1966,"Development of a vagina in male rats by inhibiting androgen receptors with an anti-androgen during the critical phase of organogenesis.","5948902","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"6030762",1967,"Postnatal development of sensitivity to estrogen and androgen in male, female and psuedohermaphroditic guinea pigs.","6030762","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"627288",1978,"[Estradiol-binding and estradiol-inhibiting capacity of the target organs in female rats with brain-disturbed sexual differentiation].","627288","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"6542899",1984,"Sexual behavior of an androgenized female rhesus macaque with a surgically constructed vagina.","6542899","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"6665350",1983,"[Receptiveness to sexual steroids. Physiopathological aspects].","6665350","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"6667844",1983,"Effects of steroids and sex reversal on intestinal absorption of L-[14C]leucine in vivo, in rainbow trout, Salmo gairdneri.","6667844","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,0,"680213",1978,"[Estradiol-binding and estradiol-retaining capacity of target organs of female rats with disorders in the sex differentiation of the brain].","680213","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"7095416",1982,"Action of estradiol on the hermaphroditism induced by testicular graft in the female chick embryo.","7095416","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"7359475",1980,"Effects of testosterone and oestrogen on serum prolactin in the androgen-insensitive rat.","7359475","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"7447380",1980,"Plasma concentration of steroid hormones after intravenous infusion of testosterone in castrated male transsexuals.","7447380","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"7584881",1995,"Bone mass in androgen-insensitivity syndrome: response to hormonal replacement therapy.","7584881","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"8499334",1993,"Endocrine differentiation of the XY sex-reversed mouse ovary during postnatal development.","8499334","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"8575652",1995,"The relative effectiveness of androstenedione, testosterone, and estrone, precursors to estradiol, in sex reversal in the red-eared slider (Trachemys scripta), a turtle with temperature-dependent sex determination.","8575652","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"8804560",1996,"Gonadal transformation in male Rana catesbeiana tadpoles intraperitoneally implanted with estradiol capsules.","8804560","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"8804562",1996,"The relative effectiveness of estrone, estradiol-17 beta, and estriol in sex reversal in the red-eared slider (Trachemys scripta), a turtle with temperature-dependent sex determination.","8804562","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"952594",1976,"[Evaluation of gonadotropic and gonadal secretions in primary abnormalities of the gonads and male pseudohermaphrodism before and after the age of puberty].","952594","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"9768658",1998,"A reliable endocrine test with human menopausal gonadotropins for diagnosis of true hermaphroditism in early infancy.","9768658","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Disorders of Sex Development",0,1,"9924012",1999,"No threshold dose for estradiol-induced sex reversal of turtle embryos: how little is too much?","9924012","Estradiol","Disorders of Sex Development",1,null,1]
["Estradiol","Epididymis",0,1,"1001264",1976,"Epididymal response to exogenous testosterone in rats sterilized neonatally by estrogen.","1001264","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"10365314",1999,"Role of estradiol in the capacitation and acrosome reaction of hamster epididymal spermatozoa in the isolated uterus of mice incubated in vitro.","10365314","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",1,1,"10453915",1999,"Reproductive function in rats exposed neonatally to bisphenol A and estradiol benzoate.","10453915","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"1186893",1975,"Alteration of epididymal sperm transport and maturation in mice by oestrogen and testosterone.","1186893","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"12211062",2002,"Effects of the aromatase inhibitor fadrozole on plasma sex steroid secretion, spermatogenesis and epididymis morphology in the lizard, Podarcis sicula.","12211062","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",1,1,"12959643",2003,"The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy.","12959643","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"14613549",2003,"The antiestrogen ICI 182,780 decreases the expression of estrogen receptor-alpha but has no effect on estrogen receptor-beta and androgen receptor in rat efferent ductules.","14613549","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"15743524",2005,"Effects of ICI 182780 on estrogen receptor expression, fluid absorption and sperm motility in the epididymis of the bonnet monkey.","15743524","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"22898016",2012,"Testicular testosterone: estradiol ratio in domestic cats and its relationship to spermatogenesis and epididymal sperm morphology.","22898016","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"23319664",2013,"In vivo exposure to 17?-estradiol triggers premature sperm capacitation in cauda epididymis.","23319664","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"2374426",1990,"Effect of Allium sativum on epididymal spermatozoa, estradiol-treated mice and general toxicity.","2374426","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"23788033",2013,"Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity.","23788033","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"40899",1978,"Possible effects of ovocyclin in male reproduction.","40899","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"4597757",1974,"The inhibition of fertilizing ability of epididymal spermatozoa by the administration of oestradiol benzoate to testosterone-maintained hypophysectomized or castrated hamsters.","4597757","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"5050147",1972,"Effect of testosterone, estradiol-17-beta and progesterone on the oxygen uptake by bovine semen, washed spermatozoa and epididymal-like spermatozoa.","5050147","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",1,1,"5843079",1965,"Changes in the epididymis associated with morphological changes in the spermatozoa.","5843079","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"6111879",1980,"Transmission and scanning electron microscopy of epididymis in male mice receiving estrogen during gestation.","6111879","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"6618997",1983,"The effect of estrogen administration in vivo on the elemental composition of the intraluminal fluids of the seminiferous tubules, rete testis, and epididymis of the rat.","6618997","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"7045269",1982,"Initiation of spermatogenesis and testicular growth in oestradiol-17 beta-implanted bull calves with pulsatile infusion of luteinizing hormone releasing hormone.","7045269","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"7422674",1980,"Long-term effects of neonatal administration of estrogen and progesterone, alone or in combination, on male BALB/c and BALB/cfC3H mice.","7422674","Estradiol","Epididymis",1,null,1]
["Estradiol","Epididymis",0,1,"801317",1976,"[The histological modifications of genital system of oestradiol benzoate treated male rats (author's transl)].","801317","Estradiol","Epididymis",1,null,1]
["Estradiol","Foreskin",0,1,"18001166",2007,"Estradiol upregulates activating transcription factor 3, a candidate gene in the etiology of hypospadias.","18001166","Estradiol","Foreskin",1,null,1]
["Estradiol","Foreskin",0,1,"20180416",2009,"[Expressions of ATF3 and CTGF and their regulation by estradiol in the prepuce of hypospadias patients].","20180416","Estradiol","Foreskin",1,null,1]
["Estradiol","Frasier Syndrome",0,0,"16717397",2006,"Lack of puberty despite elevated estradiol in a 46,XY phenotypic female with Frasier syndrome.","16717397","Estradiol","Frasier Syndrome",1,null,1]
["Estradiol","Freemartinism",0,0,"2229590",1990,"Effects of androgenizing dairy heifers with ear implants containing testosterone and estrogen on detection of estrus.","2229590","Estradiol","Freemartinism",1,null,1]
["Estradiol","Freemartinism",0,0,"335063",1977,"The acute effects of oestradiol-17beta and synthetic LH-RH on plasma LH levels in freemartin heifers.","335063","Estradiol","Freemartinism",1,null,1]
["Estradiol","Freemartinism",0,0,"994104",1976,"The acute effect of oestrogen injection on plasma LH in freemartin heifers.","994104","Estradiol","Freemartinism",1,null,1]
["Estradiol","Genitalia, Male",0,1,"11404795",2001,"Effect of intermittent treatment with tamoxifen on reproduction in male rats.","11404795","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"11686542",2001,"Antifertility effects of estradiol in adult male rats.","11686542","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"11800162",2001,"The influence of estrogen on the developing male marsupial.","11800162","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"12090921",2002,"Effects of oestrogen treatment on testicular descent, inguinal closure and prostatic development in a male marsupial, Macropus eugenii.","12090921","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"12239125",2002,"Estrogen accelerates gonadal recrudescence in photo-regressed male siberian hamsters.","12239125","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,0,"12265605",1978,"Hypogonadism in chronically lead-poisoned men.","12265605","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"1276318",1976,"The effects of 17 beta-estradiol and medroxyprogesterone acetate alone and in combination with alpha-chlorohydrin on reproductive function in the male rat.","1276318","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",1,1,"16162399",2006,"Reproductive abnormalities in adult male mice following preimplantation exposures to estradiol or pesticide methoxychlor.","16162399","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"1626917",1992,"Incomplete testicular feminization syndrome: studies of 17 beta-oestradiol-binding activity and aromatase activity in cultured genital fibroblasts showing impaired dihydrotestosterone-binding.","1626917","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"18061183",2008,"Estrogen regulation of the male reproductive tract in the frog, Rana esculenta: a role in Fra-1 activation in peritubular myoid cells and in sperm release.","18061183","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"18286211",2008,"Effects of estradiol-17beta and bisphenol A administered chronically to mice throughout pregnancy and lactation on the male pups' reproductive system.","18286211","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"18335098",2008,"Low phytoestrogen levels in feed increase fetal serum estradiol resulting in the \"fetal estrogenization syndrome\" and obesity in CD-1 mice.","18335098","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"22309682",2012,"Effects of chronic estradiol or testosterone treatment upon sexual behavior in sexually sluggish male rats.","22309682","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"3676392",1987,"Effect of estradiol-filled polydimethylsiloxane subdermal implants in adult male rats on the reproductive system, fertility, and progeny outcome.","3676392","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"4223942",1966,"[Feminization of the adult male mouse by injection of estrogens into the pregnant mother].","4223942","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",1,1,"4387385",1968,"[Genital malformations induced in adult mice by a prenatal estrogenic action. I. The male (male pseudo-hermaphroditism)].","4387385","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"4389015",1967,"[Stimulation by postnatal estrogen treatment of female genital structures obtained in male adult mice by injection of estradiol in the pregnant mother].","4389015","Estradiol","Genitalia, Male",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I1988,I1988)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J1988,J1988)","v":"Genitalia, Male"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H1988,H1988)","v":"4676748"},1972,"[Somatic sexual differentiation of rat fetuses. The action of clomiphene on fetuses whose mothers had been treated with estradiol or testosterone propionate].","4676748","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",1,1,"485634",1979,"Effects of estradiol-17 beta on reproduction in adult male rats.","485634","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"5016279",1972,"Precocious mating in male rats following treatment with androgen or estrogen.","5016279","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"5091295",1971,"Comparison of the effects of cyproterone, cyproterone acetate and oestradiol on testicular function, accessory sexual glands and fertility in a long-term study on rats.","5091295","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"5518872",1970,"[Effects of estradiol on the genital apparatus of the embryo of the Mauresque turtle (Testudo graceca L.)].","5518872","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"5688816",1968,"Production of congenital adrenocortical hyperplasia in rats by estradiol-17-beta and inhibition of 3-beta-hydroxysteroid dehydrogenase.","5688816","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"5753098",1968,"[Genital malformations in adult mice resulting from prenatal estrogenic action. II. The female].","5753098","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"6148324",1984,"Altered structural and functional integrity of the reproductive tissues in estradiol benzoate-treated intact male albino rats.","6148324","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"6685752",1983,"Plasma oestradiol-17 beta and testosterone concentrations as possible causes of the infertility of congenitally obese Zucker rats.","6685752","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"6733210",1984,"Comparison of the effects of gossypol, estradiol-17 beta and testosterone compensation on male rat reproductive organs.","6733210","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"6851565",1983,"Somatic tissue responses of male rhesus monkeys treated with a contraceptive steroid formulation.","6851565","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"6991014",1980,"Sexual differentiation: early hormone synthesis and action.","6991014","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"801317",1976,"[The histological modifications of genital system of oestradiol benzoate treated male rats (author's transl)].","801317","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"8118806",1994,"Interactive effects of unleaded gasoline and estrogen on liver tumor promotion in female B6C3F1 mice.","8118806","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"8491155",1993,"Estrogen receptors, estradiol, and diethylstilbestrol in early development: the mouse as a model for the study of estrogen receptors and estrogen sensitivity in embryonic development of male and female reproductive tracts.","8491155","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",1,1,"8667451",1995,"Collaborative work to determine the optimal administration period and parameters to detect drug effects on male rat fertility--study on estradiol benzoate effects.","8667451","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"908587",1977,"Effect of estradiol-17beta &amp; estriol-3-methyl ether on spermatozoa &amp; genital organs of rats.","908587","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"9499618",1998,"[Effect of estradiol valerate on the male reproductive organs and various semen parameters in rats].","9499618","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Genitalia, Male",0,1,"992755",1976,"Influence of testosterone &amp; estradiol-17beta on the spermatozoa &amp; accessory genital organs of castrated rats.","992755","Estradiol","Genitalia, Male",1,null,1]
["Estradiol","Gonadal Dysgenesis",0,0,"6128271",1982,"Endocrine and clinical effects of estradiol and testosterone pellets used in long-term replacement therapy.","6128271","Estradiol","Gonadal Dysgenesis",1,null,1]
["Estradiol","Gonadal Dysgenesis",0,1,"6539750",1984,"Estradiol benzoate treatment of an XY gonadal dysgenetic chacma baboon.","6539750","Estradiol","Gonadal Dysgenesis",1,null,1]
["Estradiol","Gonadal Dysgenesis",0,0,"6810024",1982,"Estradiol and progesterone receptor concentrations and 17 beta-hydroxysteroid-dehydrogenase activity in estrogen-progestin stimulated endometrium of women with gonadal dysgenesis.","6810024","Estradiol","Gonadal Dysgenesis",1,null,1]
["Estradiol","Gonadal Dysgenesis",0,0,"8177091",1994,"Transdermal estradiol plus oral medroxyprogesterone acetate replacement therapy in primary amenorrheic adolescents. Clinical, hormonal and metabolic aspects.","8177091","Estradiol","Gonadal Dysgenesis",1,null,1]
["Estradiol","Gonadal Dysgenesis, 46,XY",0,1,"1479151",1992,"In vitro effect of hCG on steroidogenesis in the testicular tissue from a patient with complete androgen resistance.","1479151","Estradiol","Gonadal Dysgenesis, 46,XY",1,null,1]
["Estradiol","Gonadal Dysgenesis, 46,XY",0,0,"16717397",2006,"Lack of puberty despite elevated estradiol in a 46,XY phenotypic female with Frasier syndrome.","16717397","Estradiol","Gonadal Dysgenesis, 46,XY",1,null,1]
["Estradiol","Gonadal Dysgenesis, 46,XY",0,0,"23812501",2013,"Unexpected labor and successful twin birth to a pure gonadal dysgenetic woman.","23812501","Estradiol","Gonadal Dysgenesis, 46,XY",1,null,1]
["Estradiol","Gonadal Dysgenesis, Mixed",1,0,"1774444",1991,"Transdermal estradiol substitution therapy for the induction of puberty in female hypogonadism.","1774444","Estradiol","Gonadal Dysgenesis, Mixed",1,null,1]
["Estradiol","Hyperandrogenism",0,0,"10078591",1999,"The effect of transdermal estrogen replacement therapy on hyperandrogenicity and glucose homeostasis in postmenopausal women with NIDDM.","10078591","Estradiol","Hyperandrogenism",1,null,1]
["Estradiol","Hyperandrogenism",0,0,"16290888",2005,"Effects of experimental hyperandrogenemia on the female rat reproductive axis: suppression of progesterone-receptor messenger RNA expression in the brain and blockade of luteinizing hormone surges.","16290888","Estradiol","Hyperandrogenism",1,null,1]
["Estradiol","Hyperandrogenism",0,0,"17274467",2006,"[Hyperandrogenism as a risk factor of coronary artery disease in young women].","17274467","Estradiol","Hyperandrogenism",1,null,1]
["Estradiol","Hyperandrogenism",0,0,"20608809",2011,"Low estradiol-to-testosterone ratio is associated with oligo-anovulatory cycles and atherogenic lipidic pattern in women with polycystic ovary syndrome.","20608809","Estradiol","Hyperandrogenism",1,null,1]
["Estradiol","Hyperandrogenism",0,0,"22201077",2011,"[Correlations between clinical signs and hormonal parameters in young women with hirsutism].","22201077","Estradiol","Hyperandrogenism",1,null,1]
["Estradiol","Hyperandrogenism",0,0,"7851579",1995,"17 beta-Estradiol: oral or parenteral administration in hyperandrogenic women? Metabolic tolerance in association with cyproterone acetate.","7851579","Estradiol","Hyperandrogenism",1,null,1]
["Estradiol","Hyperandrogenism",1,0,"7989480",1994,"Sequential estrogen-progestin addition to gonadotropin-releasing hormone agonist suppression for the chronic treatment of ovarian hyperandrogenism: a pilot study.","7989480","Estradiol","Hyperandrogenism",1,null,1]
["Estradiol","Hyperandrogenism",0,0,"8636283",1996,"High bone density in hyperandrogenic women: effect of gonadotropin-releasing hormone agonist alone or in conjunction with estrogen-progestin replacement.","8636283","Estradiol","Hyperandrogenism",1,null,1]
["Estradiol","Hypospadias",0,0,"14263903",1964,"[EFFECT OF A SINGLE DOSE OF ESTRADIOL BENZOATE ADMINISTERED BEFORE THE 5TH DAY OF LIFE ON THE GENITAL TRACT OF THE RAT].","14263903","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",1,1,"17169275",2006,"Embryonic exposure to low-dose 17beta-estradiol decreases fetal mass sex specifically in male mice and does not cause hypospadias.","17169275","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",1,1,"17302024",2007,"[Establishment of a mouse model of hypospadias induced by estradiol benzoate].","17302024","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",0,1,"18001166",2007,"Estradiol upregulates activating transcription factor 3, a candidate gene in the etiology of hypospadias.","18001166","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",0,1,"20180416",2009,"[Expressions of ATF3 and CTGF and their regulation by estradiol in the prepuce of hypospadias patients].","20180416","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",0,1,"21676446",2011,"Polymorphisms in the P450 c17 (17-hydroxylase/17, 20-Lyase) gene: association with estradiol and testosterone concentration in hypospadias.","21676446","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",0,1,"2566621",1989,"Improvement of spermatogenesis after treatment with the antiestrogen tamoxifen in a man with the incomplete androgen insensitivity syndrome.","2566621","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",1,1,"5463881",1970,"[Hypospadias induced by hormone therapy?].","5463881","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",0,0,"5654606",1968,"Abnormalities in the adult mouse vagina after neonatal estradiol treatment.","5654606","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",0,1,"5688816",1968,"Production of congenital adrenocortical hyperplasia in rats by estradiol-17-beta and inhibition of 3-beta-hydroxysteroid dehydrogenase.","5688816","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",0,1,"5753098",1968,"[Genital malformations in adult mice resulting from prenatal estrogenic action. II. The female].","5753098","Estradiol","Hypospadias",1,null,1]
["Estradiol","Hypospadias",1,0,"6740514",1984,"Direct fetal injections of diethylstilbestrol and 17 beta-estradiol: a method for investigating their teratogenicity.","6740514","Estradiol","Hypospadias",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"1017790",1976,"Oestradiol receptors in non-neoplastic gynaecomastic tissue of phenotypic males.","1017790","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"115199",1979,"Klinefelter's syndrome: effects of oestrogen on growth hormone, prolactin and thyrotrophin release, and on thyrotrophin and prolactin responses to thyrotrophin-releasing hormone.","115199","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"1157343",1975,"Hormonal studies in Klinefelter's syndrome.","1157343","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,0,"14084153",1963,"PARTITION STUDIES OF THE NEUTRAL 17-KETOSTEROIDS IN KLINEFELTER'S SYNDROME WITH A THEORY AS TO THE PATHOGENESIS OF THE SYNDROME.","14084153","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,0,"14161068",1963,"STUDIES ON THE URINARY STEROIDS IN BILATERAL GYNECOMASTIA.","14161068","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"2127042",1990,"Presence of positive feedback in males with Klinefelter's syndrome.","2127042","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"21536274",2011,"Estradiol levels in men with congenital hypogonadotropic hypogonadism and the effects of different modalities of hormonal treatment.","21536274","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"2427774",1986,"[Diagnostic value of determining the levels of testosterone, estradiol and testosterone-estradiol-binding globulin in the plasma].","2427774","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"3918293",1985,"Pituitary-gonadal function in Klinefelter syndrome before and during puberty.","3918293","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"4035118",1985,"[Testicular response to human chorionic gonadotropin in infertile patients according to the testicular histologic pattern].","4035118","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"509745",1979,"Effect of age on testicular function in patients with Klinefelter's syndrome.","509745","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"5108101",1971,"Biosynthesis of testosterone and oestrogens in vitro by the testicular tissue from patients with Klinefelter's syndrome.","5108101","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"5356914",1969,"The measurement of low levels of estrone &amp; estradiol-17-beta in urine, employing ion-exchange, thin-layer, and gas-liquid chromatography.","5356914","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"6891632",1982,"Effect of human chorionic gonadotropin on the plasma levels of testosterone, estradiol, sex hormone binding globuline and free testosterone in Klinefelter syndrome.","6891632","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"7339133",1981,"[Studies on testicular endocrinological function by estimation of plasma testosterone, estradiol and estradiol testosterone ratio. Studies on testicular function; report 9 (author's transl)].","7339133","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"7441832",1980,"Testicular function in Klinefelter's syndrome.","7441832","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"766550",1976,"Oestrone, oestradiol and testosterone in normal and hypogonadal men following LH-RH or HCG stimulation.","766550","Estradiol","Klinefelter Syndrome",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2052,I2052)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2052,J2052)","v":"Klinefelter Syndrome"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2052,H2052)","v":"9075307"},1997,"The impact of oestradiol on ages at onset in schizophrenia reevaluated through Klinefelter syndrome.","9075307","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Klinefelter Syndrome",0,1,"952594",1976,"[Evaluation of gonadotropic and gonadal secretions in primary abnormalities of the gonads and male pseudohermaphrodism before and after the age of puberty].","952594","Estradiol","Klinefelter Syndrome",1,null,1]
["Estradiol","Leydig Cell Tumor",0,1,"12443684",2002,"Blood plasma concentrations of oestradiol-17beta, testosterone and testosterone/oestradiol ratio in dogs with neoplastic and degenerative testicular diseases.","12443684","Estradiol","Leydig Cell Tumor",1,null,1]
["Estradiol","Leydig Cell Tumor",0,1,"16541728",2005,"[Important functions of estrogens in men--breakthrough in contemporary medicine].","16541728","Estradiol","Leydig Cell Tumor",1,null,1]
["Estradiol","Leydig Cells",0,1,"1001264",1976,"Epididymal response to exogenous testosterone in rats sterilized neonatally by estrogen.","1001264","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"1154993",1975,"Effect of sex steroids on the male reproductive organs of the monitor lizard Varanus monitor (Linn.).","1154993","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"12108785",2002,"Effect of compound CDRI 84/35 and synthetic estrogen on the seminiferous epithelium of immature rat.","12108785","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"12193375",2002,"Differential alteration of the reproductive axis by testosterone and estrogen in peripubertal and adult male Siberian hamsters (Phodopus sungorus).","12193375","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"1222901",1975,"The effect of 17 beta-estradiol acetate on the testis and thumb pad of Rana cyanophlyctis (Schn.) and Rana tigrina (Daud.).","1222901","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",1,1,"12657744",2003,"Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture.","12657744","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"14613549",2003,"The antiestrogen ICI 182,780 decreases the expression of estrogen receptor-alpha but has no effect on estrogen receptor-beta and androgen receptor in rat efferent ductules.","14613549","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"16768150",2006,"Bioactivity of human chorionic gonadotropin produced in frozen-thawed embryo transfer cycles with exogenous hormone replacement.","16768150","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",1,1,"17569695",2007,"Developmental changes in testicular sensitivity to estrogens throughout fetal and neonatal life.","17569695","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"18230131",2008,"Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg) mouse.","18230131","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"18465685",2008,"The effects of cryptorchidism on the regulation of steroidogenesis and gap junctional communication in equine testes.","18465685","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"19233",1977,"Estradiol binding capacity in the cryptorchid rat testis.","19233","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"1950593",1991,"Effect of estradiol on spermatogenesis and testicular hydroxysteroid dehydrogenase activities in Bidder's organectomized toad (Bufo melanostictus).","1950593","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"19595749",2009,"Effect of ETBE on reproductive steroids in male rats and rat Leydig cell cultures.","19595749","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"19903717",2010,"Induction of spermatogenic cell apoptosis in prepubertal rat testes irrespective of testicular steroidogenesis: a possible estrogenic effect of di(n-butyl) phthalate.","19903717","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"20410197",2010,"Estradiol induction of spermatogenesis is mediated via an estrogen receptor-{alpha} mechanism involving neuroendocrine activation of follicle-stimulating hormone secretion.","20410197","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"21752447",2011,"In vitro effects of estradiol-17?, monobutyl phthalate and mono-(2-ethylhexyl) phthalate on the secretion of testosterone and insulin-like peptide 3 by interstitial cells of scrotal and retained testes in dogs.","21752447","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"23283575",2013,"Cyp17a1 and Cyp19a1 in the zebrafish testis are differentially affected by oestradiol.","23283575","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"2570718",1989,"AVP receptors of mouse Leydig cells are regulated by LH and E2 and influenced by experimental cryptorchidism.","2570718","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"3134781",1987,"Demonstration of direct effect of estrogen on rat spermatogenesis.","3134781","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"3949773",1986,"Acquisition of estradiol-mediated regulatory mechanism of steroidogenesis in cultured fetal rat Leydig cells.","3949773","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",1,1,"4152351",1973,"[Growth and structure of cryptorchid testes in mice born of mothers treated by oestradiol during pregnancy (author's transl)].","4152351","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"4400631",1972,"The hormonal response to HCG stimulation in male children and adolescents.","4400631","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",1,1,"4426307",1974,"Ultrastructural changes in the testis of mice given neonatal injections of estrogen.","4426307","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"5091295",1971,"Comparison of the effects of cyproterone, cyproterone acetate and oestradiol on testicular function, accessory sexual glands and fertility in a long-term study on rats.","5091295","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"5688816",1968,"Production of congenital adrenocortical hyperplasia in rats by estradiol-17-beta and inhibition of 3-beta-hydroxysteroid dehydrogenase.","5688816","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"6050510",1967,"Effect of estradiol-17-beta on the distribution of 3-beta-hydroxysteroid dehydrogenase in the testes of Rana esculenta and Lacerta sicula.","6050510","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"6672407",1983,"Does estrogen influence the development of Leydig cells in fetal and early neonatal rats?","6672407","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"7118204",1982,"Effect of estradiol-17 beta, estradiol-17 beta + homoplastic pars distalis extract, estradiol-17 beta + testosterone &amp; testosterone on spermatogenesis, Leydig cells &amp; thumb pads in the toad Bufo melanostictus (Schn.).","7118204","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"719098",1978,"Recovery of testicular and pituitary functions in adult male rats after cessation of short and long term estradiol treatment.","719098","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"746885",1978,"[Testicular action of estrogens and antiandrogens--karyo-, histometric and histochemical studies of dog testis].","746885","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"7580026",1995,"Factors related to early pregnancy recognition in the woman.","7580026","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"8966101",1996,"[Precocious maturation of the testis associated with excessive secretion of estradiol and testosterone by Leydig cells].","8966101","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Leydig Cells",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Estradiol","Leydig Cells",1,null,1]
["Estradiol","Penis",0,1,"1120604",1975,"Androgen- and estrogen-induced copulatory behavior and inhibition of luteinizing hormone (LH) secretion in the male rat.","1120604","Estradiol","Penis",1,null,1]
["Estradiol","Penis",0,0,"14111321",1964,"[THE MECHANISM OF ACTION OF PROGESTATIONAL HORMONES IN THE ANTI-MASCULINE EFFECT ON FETAL RATS].","14111321","Estradiol","Penis",1,null,1]
["Estradiol","Penis",0,1,"3628441",1987,"Evidence for the reestablishment of copulatory behavior in castrated male rats with a brain-enhanced estradiol-chemical delivery system.","3628441","Estradiol","Penis",1,null,1]
["Estradiol","Penis",0,1,"4785735",1973,"Estrogen-activated sexual behavior in male rats.","4785735","Estradiol","Penis",1,null,1]
["Estradiol","Penis",0,1,"4856161",1974,"Neonatal bonadal hormones: effect on maternal and sexual behavior in the male rat.","4856161","Estradiol","Penis",1,null,1]
["Estradiol","Penis",0,1,"552372",1979,"Sexual behavior and penile reflexes of neonatally castrated male rats treated in infancy with estrogen and dihydrotestosterone.","552372","Estradiol","Penis",1,null,1]
["Estradiol","Penis",0,1,"7938351",1994,"Effects of sex steroids on sensory and motor spinal mechanisms.","7938351","Estradiol","Penis",1,null,1]
["Estradiol","Prostate",0,1,"10321385",1999,"Dose, timing, and duration of flaxseed exposure affect reproductive indices and sex hormone levels in rats.","10321385","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",1,1,"10613394",1999,"Perinatal exposure to estrogenic compounds and the subsequent effects on the prostate of the adult rat: evaluation of inflammation in the ventral and lateral lobes.","10613394","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"1120604",1975,"Androgen- and estrogen-induced copulatory behavior and inhibition of luteinizing hormone (LH) secretion in the male rat.","1120604","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"12011486",2002,"2,3,7,8-tetrachlorodibenzo-p-dioxin interacts with endogenous estradiol to disrupt prostate gland morphogenesis in male rat fetuses.","12011486","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"12090921",2002,"Effects of oestrogen treatment on testicular descent, inguinal closure and prostatic development in a male marsupial, Macropus eugenii.","12090921","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"1372243",1992,"The effect of androgen, estrogen, and growth factors on the proliferation of cultured fibroblasts derived from human fetal and adult prostates.","1372243","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,0,"14111321",1964,"[THE MECHANISM OF ACTION OF PROGESTATIONAL HORMONES IN THE ANTI-MASCULINE EFFECT ON FETAL RATS].","14111321","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"14677761",2003,"Pneumadin in the ventral prostate and seminal vesicles of estradiol-treated rats: RIA and immunocytochemical studies.","14677761","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"15619916",1980,"Antagonistic effects of cyproterone acetate and oestradiol on the development of the fetal rat prostate gland induced by androgens in organ culture.","15619916","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"1668899",1991,"Inhibition of fertility in the male mouse by combined androgen-antiandrogen therapy.","1668899","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",1,1,"16740699",2006,"Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4.","16740699","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",1,1,"18226066",2008,"Perinatal exposure to oestradiol and bisphenol A alters the prostate epigenome and increases susceptibility to carcinogenesis.","18226066","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"19037884",2009,"Use of intralesional oestradiol concentration to identify a functional pulmonary metastasis of canine sertoli cell tumour.","19037884","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"20353424",2010,"Tissue changes in senescent gerbil prostate after hormone deprivation leads to acquisition of androgen insensitivity.","20353424","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"242175",1975,"The effect of artificial cryptorchidism on serum oestrogen and testosterone levels in the adult male rat.","242175","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"4110091",1971,"Studies on the endocrine properties of a new progestational steroid 4,6-dichloro-16-methylene-17-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate (MDAP).","4110091","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"4405594",1972,"[Comparative study of changes in gonadotropic cells and testis in male rats treated with estrogens during the neonatal period].","4405594","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"4476935",1974,"A new class of long-acting hormonal steroid preparation: synthesis of dimeric ethynodiol and nortestosterone, of dimeric and trimeric androgens and of some dimeric combinations of steroids.","4476935","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"4536880",1972,"Neonatal sterilization of rodents with steroid hormones. 4. The influence of estradiol benzoate injected into five day old male rats on the weight of testes and ventral prostate and histology of the seminiferous epithelium and the pituitary gland during sexual maturation.","4536880","Estradiol","Prostate",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2116,I2116)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2116,J2116)","v":"Prostate"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2116,H2116)","v":"4675694"},1972,"[The effect of ethymizole on the gonadotropic function of the hypophysis].","4675694","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"4735548",1973,"Serum and pituitary prolactin, LH, and FSH in androgenized female and normal male rats treated with various doses of estradiol benzoate.","4735548","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"486667",1979,"Interactions of testosterone and estradiol-17 beta on the reproductive tract of the male rat.","486667","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"5091295",1971,"Comparison of the effects of cyproterone, cyproterone acetate and oestradiol on testicular function, accessory sexual glands and fertility in a long-term study on rats.","5091295","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"5167855",1971,"[Oestrogens in small animals, with exception of the female genital tract].","5167855","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"801317",1976,"[The histological modifications of genital system of oestradiol benzoate treated male rats (author's transl)].","801317","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"9050904",1997,"Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses.","9050904","Estradiol","Prostate",1,null,1]
["Estradiol","Prostate",0,1,"909588",1977,"Synergistic interaction of testosterone and oestradiol inhibits spermatogenesis in rats.","909588","Estradiol","Prostate",1,null,1]
["Estradiol","Prostatic Neoplasms",0,1,"10843196",2000,"Estradiol acts as a germ cell survival factor in the human testis in vitro.","10843196","Estradiol","Prostatic Neoplasms",1,null,1]
["Estradiol","Prostatic Neoplasms",1,1,"11085521",2000,"Sex hormone-induced carcinogenesis in Rb-deficient prostate tissue.","11085521","Estradiol","Prostatic Neoplasms",1,null,1]
["Estradiol","Prostatic Neoplasms",1,1,"11507055",2001,"A human prostatic epithelial model of hormonal carcinogenesis.","11507055","Estradiol","Prostatic Neoplasms",1,null,1]
["Estradiol","Prostatic Neoplasms",0,1,"16541728",2005,"[Important functions of estrogens in men--breakthrough in contemporary medicine].","16541728","Estradiol","Prostatic Neoplasms",1,null,1]
["Estradiol","Prostatic Neoplasms",1,1,"16740699",2006,"Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4.","16740699","Estradiol","Prostatic Neoplasms",1,null,1]
["Estradiol","Prostatic Neoplasms",0,1,"17486276",2007,"Expression of Nkx3.1 enhances 17beta-estradiol anti-tumor action in PC3 human prostate cancer cells.","17486276","Estradiol","Prostatic Neoplasms",1,null,1]
["Estradiol","Prostatic Neoplasms",1,1,"18226066",2008,"Perinatal exposure to oestradiol and bisphenol A alters the prostate epigenome and increases susceptibility to carcinogenesis.","18226066","Estradiol","Prostatic Neoplasms",1,null,1]
["Estradiol","Prostatic Neoplasms",1,1,"8765520",1996,"Design, synthesis, and biological evaluation of ellipticine-estradiol conjugates.","8765520","Estradiol","Prostatic Neoplasms",1,null,1]
["Estradiol","Rete Testis",1,1,"12959643",2003,"The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy.","12959643","Estradiol","Rete Testis",1,null,1]
["Estradiol","Rete Testis",0,1,"9737741",1998,"Neonatal exposure of male rats to estradiol benzoate causes rete testis dilation and backflow impairment of spermatogenesis.","9737741","Estradiol","Rete Testis",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"1120604",1975,"Androgen- and estrogen-induced copulatory behavior and inhibition of luteinizing hormone (LH) secretion in the male rat.","1120604","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"11478683",2001,"Genetic variation in physiological sensitivity to estrogen in mice.","11478683","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"1151930",1975,"Altered sexual development in male rats after oestrogen administration during the neonatal period.","1151930","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"14677761",2003,"Pneumadin in the ventral prostate and seminal vesicles of estradiol-treated rats: RIA and immunocytochemical studies.","14677761","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",1,1,"16162399",2006,"Reproductive abnormalities in adult male mice following preimplantation exposures to estradiol or pesticide methoxychlor.","16162399","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"18230131",2008,"Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg) mouse.","18230131","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"20410197",2010,"Estradiol induction of spermatogenesis is mediated via an estrogen receptor-{alpha} mechanism involving neuroendocrine activation of follicle-stimulating hormone secretion.","20410197","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"242175",1975,"The effect of artificial cryptorchidism on serum oestrogen and testosterone levels in the adult male rat.","242175","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"4110091",1971,"Studies on the endocrine properties of a new progestational steroid 4,6-dichloro-16-methylene-17-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate (MDAP).","4110091","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"440530",1979,"Activation of masculine sexual behavior by intracranial estradiol benzoate implants in male rats.","440530","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"4405594",1972,"[Comparative study of changes in gonadotropic cells and testis in male rats treated with estrogens during the neonatal period].","4405594","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"4476935",1974,"A new class of long-acting hormonal steroid preparation: synthesis of dimeric ethynodiol and nortestosterone, of dimeric and trimeric androgens and of some dimeric combinations of steroids.","4476935","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"4597757",1974,"The inhibition of fertilizing ability of epididymal spermatozoa by the administration of oestradiol benzoate to testosterone-maintained hypophysectomized or castrated hamsters.","4597757","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"4675694",1972,"[The effect of ethymizole on the gonadotropic function of the hypophysis].","4675694","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"4678851",1972,"Effects of gonadotropins on the occurrence of permanent changes in the testis of mice given neonatal estrogen injections.","4678851","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"4735548",1973,"Serum and pituitary prolactin, LH, and FSH in androgenized female and normal male rats treated with various doses of estradiol benzoate.","4735548","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"4742008",1973,"Fertilizing ability of hamster spermatozoa following subcutaneous implantation or insertion into seminal vesicles of silastic tubes containing estradiol benzoate.","4742008","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"4778697",1973,"[The effect of unilateral castration on the testes of mature rats receiving repeated injections of estradiol-propionate].","4778697","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"4812464",1974,"Effects of testosterone and follicle-stimulating hormone on spermatogenesis in adult mice during treatment with oestradiol.","4812464","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"486667",1979,"Interactions of testosterone and estradiol-17 beta on the reproductive tract of the male rat.","486667","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"5091295",1971,"Comparison of the effects of cyproterone, cyproterone acetate and oestradiol on testicular function, accessory sexual glands and fertility in a long-term study on rats.","5091295","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"5793461",1969,"Testicular development in rats treated with several steroids shortly after birth.","5793461","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"656527",1978,"Estrogens in the seminal vesicle fluid and the effect of exogenous estradiol-17beta on hormonal profile in the male rat.","656527","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"7938351",1994,"Effects of sex steroids on sensory and motor spinal mechanisms.","7938351","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"801317",1976,"[The histological modifications of genital system of oestradiol benzoate treated male rats (author's transl)].","801317","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminal Vesicles",0,1,"909588",1977,"Synergistic interaction of testosterone and oestradiol inhibits spermatogenesis in rats.","909588","Estradiol","Seminal Vesicles",1,null,1]
["Estradiol","Seminiferous Epithelium",0,1,"10919273",2000,"Estrogenic induction of spermatogenesis in the hypogonadal mouse.","10919273","Estradiol","Seminiferous Epithelium",1,null,1]
["Estradiol","Seminiferous Epithelium",0,1,"12108785",2002,"Effect of compound CDRI 84/35 and synthetic estrogen on the seminiferous epithelium of immature rat.","12108785","Estradiol","Seminiferous Epithelium",1,null,1]
["Estradiol","Seminiferous Epithelium",1,1,"12959643",2003,"The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy.","12959643","Estradiol","Seminiferous Epithelium",1,null,1]
["Estradiol","Seminiferous Epithelium",0,1,"15936871",2005,"Effect of high intratesticular estrogen on the seminiferous epithelium in adult male rats.","15936871","Estradiol","Seminiferous Epithelium",1,null,1]
["Estradiol","Seminiferous Epithelium",0,1,"16264094",2005,"Estrogenic induction of spermatogenesis in the hypogonadal (hpg) mouse: role of androgens.","16264094","Estradiol","Seminiferous Epithelium",1,null,1]
["Estradiol","Seminiferous Epithelium",0,1,"18230131",2008,"Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg) mouse.","18230131","Estradiol","Seminiferous Epithelium",1,null,1]
["Estradiol","Seminiferous Epithelium",0,1,"21333471",2011,"Early prepubertal testis criteria, seminiferous epithelium and hormone concentrations as related to testicular development in beef bulls.","21333471","Estradiol","Seminiferous Epithelium",1,null,1]
["Estradiol","Seminiferous Epithelium",0,1,"21915674",2011,"Altered phosphorylation and distribution status of vimentin in rat seminiferous epithelium following 17?-estradiol treatment.","21915674","Estradiol","Seminiferous Epithelium",1,null,1]
["Estradiol","Seminiferous Epithelium",0,1,"9227358",1997,"Apoptosis pattern elicited by oestradiol treatment of the seminiferous epithelium of the adult rat.","9227358","Estradiol","Seminiferous Epithelium",1,null,1]
["Estradiol","Seminiferous Epithelium",0,1,"9675620",1998,"Apoptosis precedes detachment of germ cells from the seminiferous epithelium after hormone suppression by short-term oestradiol treatment of rats.","9675620","Estradiol","Seminiferous Epithelium",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"10843196",2000,"Estradiol acts as a germ cell survival factor in the human testis in vitro.","10843196","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"10919273",2000,"Estrogenic induction of spermatogenesis in the hypogonadal mouse.","10919273","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"11390175",2001,"Actions of the endocrine disruptor methoxychlor and its estrogenic metabolite on in vitro embryonic rat seminiferous cord formation and perinatal testis growth.","11390175","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"11403898",2001,"Estradiol enhances the stimulatory effect of FSH on testicular maturation and contributes to precocious initiation of spermatogenesis.","11403898","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"11466233",2001,"Estrogen-induced gonadal sex reversal in the tammar wallaby.","11466233","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"12193375",2002,"Differential alteration of the reproductive axis by testosterone and estrogen in peripubertal and adult male Siberian hamsters (Phodopus sungorus).","12193375","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"12722",1976,"[Effect of neonatal injections of estradiol, testosterone and cryproterone acetate on plasma and testicular testosterone and on the genital system in adult male mice].","12722","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",1,1,"14555199",2003,"Male reproductive effects of octylphenol and estradiol in Fischer and Wistar rats.","14555199","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",1,1,"1666271",1991,"Morphological effects of the catecholestrogens on cells of the seminiferous tubules of Sprague-Dawley rats.","1666271","Estradiol","Seminiferous Tubules",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2180,I2180)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2180,J2180)","v":"Seminiferous Tubules"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2180,H2180)","v":"1719410"},1991,"Testicular toxicity and mutagenicity of steroidal and non-steroidal estrogens in the male mouse.","1719410","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"18097524",2008,"Maturation, proliferation and apoptosis of seminal tubule cells at puberty after administration of estradiol, follicle stimulating hormone or both.","18097524","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"18292837",2007,"During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.","18292837","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"1968991",1990,"Peripheral plasma levels of LH, testosterone, and estradiol-17 beta before and after orchiopexy in unilaterally cryptorchid dogs.","1968991","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"2117584",1990,"Prolonged suppression of spermatogenesis by oestrogen does not preserve the seminiferous epithelium in procarbazine-treated rats.","2117584","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"21333471",2011,"Early prepubertal testis criteria, seminiferous epithelium and hormone concentrations as related to testicular development in beef bulls.","21333471","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"21535008",2011,"Testosterone and oestradiol in concert protect seminiferous tubule maturation against inhibition by GnRH-antagonist.","21535008","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"21718987",2011,"Apoptosis-inhibitor Aven is downregulated in defective spermatogenesis and a novel estrogen target gene in mammalian testis.","21718987","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"22180637",2012,"17?-Estradiol regulates cyclin A1 and cyclin B1 gene expression in adult rat seminiferous tubules.","22180637","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"24011196",2013,"Estradiol and testosterone inhibit rat seminiferous tubule development in a hormone-specific way.","24011196","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"311733",1978,"Maturation of 17 beta-estradiol binding protein in the hypothalamus and anterior pituitary of male rats.","311733","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"6618997",1983,"The effect of estrogen administration in vivo on the elemental composition of the intraluminal fluids of the seminiferous tubules, rete testis, and epididymis of the rat.","6618997","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"7122318",1982,"Effects of cyproterone acetate and oestradiol benzoate on the rat testis. Morphometric study after treatment over 35 days.","7122318","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"801317",1976,"[The histological modifications of genital system of oestradiol benzoate treated male rats (author's transl)].","801317","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"8760854",1996,"Further observations on the early events that contribute to establishing the morphological pattern shown by the oestradiol suppressed testis.","8760854","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"8940662",1996,"Induction of apoptotic cell death in the seminiferous tubule of the adult rat testis: assessment of the germ cell types that exhibit the ability to enter apoptosis after hormone suppression by oestradiol treatment.","8940662","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"9737741",1998,"Neonatal exposure of male rats to estradiol benzoate causes rete testis dilation and backflow impairment of spermatogenesis.","9737741","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Seminiferous Tubules",0,1,"992971",1976,"Hormonal control of seminiferous tubule contractions. A hypothesis of sperm transport from the testicle.","992971","Estradiol","Seminiferous Tubules",1,null,1]
["Estradiol","Sertoli Cell Tumor",0,1,"12443684",2002,"Blood plasma concentrations of oestradiol-17beta, testosterone and testosterone/oestradiol ratio in dogs with neoplastic and degenerative testicular diseases.","12443684","Estradiol","Sertoli Cell Tumor",1,null,1]
["Estradiol","Sertoli Cell Tumor",0,1,"19037884",2009,"Use of intralesional oestradiol concentration to identify a functional pulmonary metastasis of canine sertoli cell tumour.","19037884","Estradiol","Sertoli Cell Tumor",1,null,1]
["Estradiol","Sertoli Cell Tumor",0,1,"4479558",1974,"Testosterone and oestradiol in dogs with testicular tumours.","4479558","Estradiol","Sertoli Cell Tumor",1,null,1]
["Estradiol","Sertoli Cell Tumor",0,1,"6850507",1983,"Large-cell calcifying sertoli cell tumor of the testis. An ultrastructural, immunocytochemical, and biochemical study.","6850507","Estradiol","Sertoli Cell Tumor",1,null,1]
["Estradiol","Sertoli Cells",0,1,"11403898",2001,"Estradiol enhances the stimulatory effect of FSH on testicular maturation and contributes to precocious initiation of spermatogenesis.","11403898","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",1,1,"11403906",2001,"beta-estradiol 3-benzoate affects spermatogenesis in the adult mouse.","11403906","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"11466233",2001,"Estrogen-induced gonadal sex reversal in the tammar wallaby.","11466233","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"12108785",2002,"Effect of compound CDRI 84/35 and synthetic estrogen on the seminiferous epithelium of immature rat.","12108785","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",1,1,"12657744",2003,"Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture.","12657744","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"14613549",2003,"The antiestrogen ICI 182,780 decreases the expression of estrogen receptor-alpha but has no effect on estrogen receptor-beta and androgen receptor in rat efferent ductules.","14613549","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"16313069",2005,"Effect of estradiol on expression of cytoskeletal proteins during spermatogenesis in testis of sexually mature rats.","16313069","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"16756952",2006,"Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in the mouse testis.","16756952","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"18061183",2008,"Estrogen regulation of the male reproductive tract in the frog, Rana esculenta: a role in Fra-1 activation in peritubular myoid cells and in sperm release.","18061183","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"18230131",2008,"Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg) mouse.","18230131","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"18292837",2007,"During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.","18292837","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"19007549",2008,"Oestradiol-induced spermatogenesis requires a functional androgen receptor.","19007549","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"204528",1978,"Secretion of proteins by Sertoli cell enriched cultures: effects of follicle stimulating hormone, dibutyryl cAMP and testosterone and correlation with secretion of oestradiol and androgen binding protein.","204528","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"21535008",2011,"Testosterone and oestradiol in concert protect seminiferous tubule maturation against inhibition by GnRH-antagonist.","21535008","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"21915674",2011,"Altered phosphorylation and distribution status of vimentin in rat seminiferous epithelium following 17?-estradiol treatment.","21915674","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"23220551",2013,"Regulation of apoptotic signaling pathways by 5?-dihydrotestosterone and 17?-estradiol in immature rat Sertoli cells.","23220551","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"3026395",1986,"Possible involvement of germ cells in the regulation of oestradiol-17 beta and ABP secretion by immature rat Sertoli cells (in vitro studies).","3026395","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"395188",1979,"Recent advances in studies on estrogen biosynthesis.","395188","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",1,1,"4426307",1974,"Ultrastructural changes in the testis of mice given neonatal injections of estrogen.","4426307","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"4716418",1973,"The normal development of the blood-testis barrier and the effects of clomiphene and estrogen treatment.","4716418","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"4812464",1974,"Effects of testosterone and follicle-stimulating hormone on spermatogenesis in adult mice during treatment with oestradiol.","4812464","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"6850507",1983,"Large-cell calcifying sertoli cell tumor of the testis. An ultrastructural, immunocytochemical, and biochemical study.","6850507","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",0,1,"8760854",1996,"Further observations on the early events that contribute to establishing the morphological pattern shown by the oestradiol suppressed testis.","8760854","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli Cells",1,1,"9742654",1998,"Effects of dietary 17 beta-estradiol exposure on serum hormone concentrations and testicular parameters in male Crl:CD BR rats.","9742654","Estradiol","Sertoli Cells",1,null,1]
["Estradiol","Sertoli-Leydig Cell Tumor",0,0,"7732806",1995,"In vitro production of cyclic AMP and steroids from an ovarian Sertoli-Leydig cell tumor. Notes on clinical management.","7732806","Estradiol","Sertoli-Leydig Cell Tumor",1,null,1]
["Estradiol","Sexual Infantilism",0,0,"14233067",1964,"[THE RELATIONSHIP BETWEEN VAGINAL CYTOLOGY AND ESTROGENURIA].","14233067","Estradiol","Sexual Infantilism",1,null,1]
["Estradiol","Sperm Count",0,1,"11686542",2001,"Antifertility effects of estradiol in adult male rats.","11686542","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"11964216",2002,"Seminal plasma melatonin and gonadal steroids concentrations in normal men.","11964216","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"12108785",2002,"Effect of compound CDRI 84/35 and synthetic estrogen on the seminiferous epithelium of immature rat.","12108785","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",1,1,"12959643",2003,"The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy.","12959643","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"15159111",2004,"Improvement in spermatogenic function after subcutaneous implantation of a capsule containing an aromatase inhibitor in four oligozoospermic dogs and one azoospermic dog with high plasma estradiol-17beta concentrations.","15159111","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"15743524",2005,"Effects of ICI 182780 on estrogen receptor expression, fluid absorption and sperm motility in the epididymis of the bonnet monkey.","15743524","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"15930179",2005,"Oestrogen does not affect the restoration of spermatogenesis in the gonadotrophin-releasing hormone-immunised adult rat.","15930179","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"16707209",2006,"Estradiol affects androgen-binding protein expression and fertilizing ability of spermatozoa in adult male rats.","16707209","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"17086699",2006,"[Research in the relation between telomerase reverse transcriptase expression in spermatogenic cells and serum levels of estradiol of fluorotic rats].","17086699","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"1752450",1991,"[Serum concentrations of estradiol and testosterone in patients with oligoasthenozoospermia and asthenozoospermia].","1752450","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"20820944",2011,"Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17?-estradiol level in induction of acute oxidative stress.","20820944","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"2117584",1990,"Prolonged suppression of spermatogenesis by oestrogen does not preserve the seminiferous epithelium in procarbazine-treated rats.","2117584","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"22732148",2012,"Does last week's alcohol intake affect semen quality or reproductive hormones? A cross-sectional study among healthy young Danish men.","22732148","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"22898016",2012,"Testicular testosterone: estradiol ratio in domestic cats and its relationship to spermatogenesis and epididymal sperm morphology.","22898016","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"3088806",1986,"[Fluctuation in the concentration of sex steroids and aflatoxin B1 in the seminal plasma of boars and its relation to sperm production].","3088806","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"6105952",1980,"Cryptorchid rhesus macaques: long term studies on changes in gonadotropins and gonadal steroids.","6105952","Estradiol","Sperm Count",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2244,I2244)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2244,J2244)","v":"Sperm Count"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2244,H2244)","v":"6148324"},1984,"Altered structural and functional integrity of the reproductive tissues in estradiol benzoate-treated intact male albino rats.","6148324","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"6431658",1984,"Endocrine profile and seminal plasma composition in Hansen's disease.","6431658","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"6833460",1983,"Human chorionic gonadotropin and testicular function: stimulation of testosterone, testosterone precursors, and sperm production despite high estradiol levels.","6833460","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"7386781",1980,"[Steroid sex hormone level in the ejaculate of healthy, fertile men].","7386781","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"8120181",1994,"Semen quality and behavior of Holstein bulls exposed to estradiol-treated bulls for mounts.","8120181","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"8498869",1993,"Concentrations of intracellular sex steroids in human spermatozoa.","8498869","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"9139423",1996,"[The effect of the season and sexual stress on the concentration of testosterone and estradiol-17beta in the seminal plasma of stallions].","9139423","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Count",0,1,"9233515",1997,"Changes in plasma luteinizing hormone, testosterone and estradiol-17 beta levels and semen quality after injections of gonadotropin releasing hormone agonist and human chorionic gonadotropin in three dogs with oligozoospermia and two dogs with azoospermia.","9233515","Estradiol","Sperm Count",1,null,1]
["Estradiol","Sperm Head",0,1,"1186893",1975,"Alteration of epididymal sperm transport and maturation in mice by oestrogen and testosterone.","1186893","Estradiol","Sperm Head",1,null,1]
["Estradiol","Sperm Head",1,1,"1719410",1991,"Testicular toxicity and mutagenicity of steroidal and non-steroidal estrogens in the male mouse.","1719410","Estradiol","Sperm Head",1,null,1]
["Estradiol","Sperm Head",0,1,"485657",1979,"Binding of 17-beta-estradiol to the outer surface and nucleus of human spermatozoa.","485657","Estradiol","Sperm Head",1,null,1]
["Estradiol","Sperm Maturation",0,1,"1186893",1975,"Alteration of epididymal sperm transport and maturation in mice by oestrogen and testosterone.","1186893","Estradiol","Sperm Maturation",1,null,1]
["Estradiol","Sperm Maturation",0,1,"15743524",2005,"Effects of ICI 182780 on estrogen receptor expression, fluid absorption and sperm motility in the epididymis of the bonnet monkey.","15743524","Estradiol","Sperm Maturation",1,null,1]
["Estradiol","Sperm Maturation",0,1,"6618997",1983,"The effect of estrogen administration in vivo on the elemental composition of the intraluminal fluids of the seminiferous tubules, rete testis, and epididymis of the rat.","6618997","Estradiol","Sperm Maturation",1,null,1]
["Estradiol","Sperm Motility",0,1,"11686542",2001,"Antifertility effects of estradiol in adult male rats.","11686542","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"11964216",2002,"Seminal plasma melatonin and gonadal steroids concentrations in normal men.","11964216","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",1,1,"12959643",2003,"The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy.","12959643","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"14709824",2003,"Therapeutic effect of aromatase inhibitor in two azoospermic dogs with high plasma estradiol-17beta levels.","14709824","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"15159111",2004,"Improvement in spermatogenic function after subcutaneous implantation of a capsule containing an aromatase inhibitor in four oligozoospermic dogs and one azoospermic dog with high plasma estradiol-17beta concentrations.","15159111","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"15743524",2005,"Effects of ICI 182780 on estrogen receptor expression, fluid absorption and sperm motility in the epididymis of the bonnet monkey.","15743524","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"16078571",2005,"[Effects of estrogen on acrosome reaction and intracellular calcium in human spermatozoa and the possible mechanism concerned].","16078571","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"16837076",2006,"Effect of 17beta-estradiol on gamete quality and maturation in two salmonid species.","16837076","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,0,"17107511",2006,"The role of oestradiol in the uterine peristalsis in the perfused swine uterus.","17107511","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"1860676",1991,"[Inhibin, steroid hormone, and gonadotropin concentration in blood from fertile and infertile males and its relationship with testicular function].","1860676","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"19996653",2009,"Role of testosterone/estradiol ratio in predicting the efficacy of tamoxifen citrate treatment in idiopathic oligoasthenoteratozoospermic men.","19996653","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"2011591",1991,"Sperm attraction to a follicular factor(s) correlates with human egg fertilizability.","2011591","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"20820944",2011,"Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17?-estradiol level in induction of acute oxidative stress.","20820944","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",1,1,"22388924",2012,"Impairments in aromatase expression, reproductive behavior, and sperm quality of male fish exposed to 17?-estradiol.","22388924","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"22898016",2012,"Testicular testosterone: estradiol ratio in domestic cats and its relationship to spermatogenesis and epididymal sperm morphology.","22898016","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"2358078",1990,"Serum hormone levels affect sperm function.","2358078","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"2497096",1989,"Indomethacin and oxaprozin lower seminal prostaglandin levels but do not influence sperm motion characteristics and serum hormones of young healthy men in a placebo-controlled double-blind trial.","2497096","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"2566621",1989,"Improvement of spermatogenesis after treatment with the antiestrogen tamoxifen in a man with the incomplete androgen insensitivity syndrome.","2566621","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"2757457",1989,"Stimulation of motility and energy metabolism of spermatozoa from asthenozoospermic patients by 17 beta-estradiol.","2757457","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"40899",1978,"Possible effects of ovocyclin in male reproduction.","40899","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"6148324",1984,"Altered structural and functional integrity of the reproductive tissues in estradiol benzoate-treated intact male albino rats.","6148324","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"6431658",1984,"Endocrine profile and seminal plasma composition in Hansen's disease.","6431658","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"690978",1978,"The metabolism and motility of human spermatozoa in the presence of steroid hormones and synthetic progestagens.","690978","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"9139423",1996,"[The effect of the season and sexual stress on the concentration of testosterone and estradiol-17beta in the seminal plasma of stallions].","9139423","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"9233515",1997,"Changes in plasma luteinizing hormone, testosterone and estradiol-17 beta levels and semen quality after injections of gonadotropin releasing hormone agonist and human chorionic gonadotropin in three dogs with oligozoospermia and two dogs with azoospermia.","9233515","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"924007",1977,"The metabolism and motility of human spermatozoa in the presence of steroid hormones and synthetic progestagens.","924007","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"9475054",1997,"In-vitro effect of estrogen-antagonist on motility and penetration ability of human spermatozoa.","9475054","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Sperm Motility",0,1,"9499618",1998,"[Effect of estradiol valerate on the male reproductive organs and various semen parameters in rats].","9499618","Estradiol","Sperm Motility",1,null,1]
["Estradiol","Spermatic Cord",0,1,"4259253",1972,"Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.","4259253","Estradiol","Spermatic Cord",1,null,1]
["Estradiol","Spermatids",1,1,"10455051",1999,"Genetic variation in susceptibility to endocrine disruption by estrogen in mice.","10455051","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",1,1,"11403906",2001,"beta-estradiol 3-benzoate affects spermatogenesis in the adult mouse.","11403906","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"12108785",2002,"Effect of compound CDRI 84/35 and synthetic estrogen on the seminiferous epithelium of immature rat.","12108785","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"12914527",2003,"Steroids control the aromatase gene expression in purified germ cells from the adult male rat.","12914527","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"15930179",2005,"Oestrogen does not affect the restoration of spermatogenesis in the gonadotrophin-releasing hormone-immunised adult rat.","15930179","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"16756952",2006,"Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in the mouse testis.","16756952","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"16830234",2006,"Estradiol treatment induces testicular oxidative stress and germ cell apoptosis in rats.","16830234","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"17086699",2006,"[Research in the relation between telomerase reverse transcriptase expression in spermatogenic cells and serum levels of estradiol of fluorotic rats].","17086699","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",1,1,"1719410",1991,"Testicular toxicity and mutagenicity of steroidal and non-steroidal estrogens in the male mouse.","1719410","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"18230131",2008,"Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg) mouse.","18230131","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"18649742",2008,"[17 beta-estradiol inhibits T-type calcium channels in mouse spermatogenic cells].","18649742","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"19095743",2009,"Disruption of tubulobulbar complex by high intratesticular estrogens leading to failed spermiation.","19095743","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"19420009",2009,"Oestrogen-induced androgen insufficiency results in a reduction of proliferation and differentiation of spermatogonia in the zebrafish testis.","19420009","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"21915674",2011,"Altered phosphorylation and distribution status of vimentin in rat seminiferous epithelium following 17?-estradiol treatment.","21915674","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"23677985",2013,"Low 17beta-estradiol levels in CNR1 knock-out mice affect spermatid chromatin remodeling by interfering with chromatin reorganization.","23677985","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"486667",1979,"Interactions of testosterone and estradiol-17 beta on the reproductive tract of the male rat.","486667","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatids",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Estradiol","Spermatids",1,null,1]
["Estradiol","Spermatocytes",0,1,"11014502",2000,"Effects of sex steroid hormones and their antagonists on mast cell number in the testis of the frog, Rana esculenta.","11014502","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"12914527",2003,"Steroids control the aromatase gene expression in purified germ cells from the adult male rat.","12914527","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"1305122",1992,"Effect of estradiol treatment on male mice synaptonemal complexes: difference of sensitivity between neonates and adults.","1305122","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"1374154",1992,"Synaptonemal complex alterations in X-irradiated and in oestrogen-treated mice: a comparative study.","1374154","Estradiol","Spermatocytes",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2308,I2308)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2308,J2308)","v":"Spermatocytes"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2308,H2308)","v":"15930179"},2005,"Oestrogen does not affect the restoration of spermatogenesis in the gonadotrophin-releasing hormone-immunised adult rat.","15930179","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"15991248",2006,"17-beta-estradiol elicits genomic and non-genomic responses in mouse male germ cells.","15991248","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"16870949",2006,"Effects of estradiol infusion in GnRH immunized boars on spermatogenesis.","16870949","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"20132863",2010,"17 beta-estradiol activates rapid signaling pathways involved in rat pachytene spermatocytes apoptosis through GPR30 and ER alpha.","20132863","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"21228613",2011,"Effects of raloxifene on voltage-dependent T-type Ca2+ channels in mouse spermatogenic cells.","21228613","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"22306083",2012,"17?-Estradiol activates GPER- and ESR1-dependent pathways inducing apoptosis in GC-2 cells, a mouse spermatocyte-derived cell line.","22306083","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"22334722",2012,"Perinatal programming of adult rat germ cell death after exposure to xenoestrogens: role of microRNA miR-29 family in the down-regulation of DNA methyltransferases and Mcl-1.","22334722","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"22860010",2012,"Proteomic changes in rat spermatogenesis in response to in vivo androgen manipulation; impact on meiotic cells.","22860010","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"23788033",2013,"Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity.","23788033","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"311733",1978,"Maturation of 17 beta-estradiol binding protein in the hypothalamus and anterior pituitary of male rats.","311733","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"3240941",1988,"Quantitative analysis of spermatogonial germ cells in adult rats treated with oestradiol benzoate alone &amp; in combination with testosterone propionate.","3240941","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"7388109",1980,"Failure of estrogen administered to adult rats to suppress meiotic DNA synthesis and differentiation of spermatocytes.","7388109","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"746885",1978,"[Testicular action of estrogens and antiandrogens--karyo-, histometric and histochemical studies of dog testis].","746885","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatocytes",0,1,"9499618",1998,"[Effect of estradiol valerate on the male reproductive organs and various semen parameters in rats].","9499618","Estradiol","Spermatocytes",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1001264",1976,"Epididymal response to exogenous testosterone in rats sterilized neonatally by estrogen.","1001264","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1017790",1976,"Oestradiol receptors in non-neoplastic gynaecomastic tissue of phenotypic males.","1017790","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"10381840",1999,"Hormone pretreatment enhances recovery of spermatogenesis in rats after neutron irradiation.","10381840","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"10455051",1999,"Genetic variation in susceptibility to endocrine disruption by estrogen in mice.","10455051","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"10484726",1999,"Animal testing. One mouse's meat is another one's poison.","10484726","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"10527870",1999,"Estradiol-17beta stimulates the renewal of spermatogonial stem cells in males.","10527870","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"10686218",2000,"Oestradiol enhances testosterone-induced suppression of human spermatogenesis.","10686218","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"10919273",2000,"Estrogenic induction of spermatogenesis in the hypogonadal mouse.","10919273","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"11014502",2000,"Effects of sex steroid hormones and their antagonists on mast cell number in the testis of the frog, Rana esculenta.","11014502","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"11018755",2000,"Estradiol-induced mitogen-activated protein kinase (extracellular signal-regulated kinase 1 and 2) activity in the frog (Rana esculenta) testis.","11018755","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"11133006",2000,"Effect of testosterone and 17beta-estradiol treatment on sex steroid binding proteins in the male of the green frog Rana esculenta.","11133006","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"11403898",2001,"Estradiol enhances the stimulatory effect of FSH on testicular maturation and contributes to precocious initiation of spermatogenesis.","11403898","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"11403906",2001,"beta-estradiol 3-benzoate affects spermatogenesis in the adult mouse.","11403906","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"11478683",2001,"Genetic variation in physiological sensitivity to estrogen in mice.","11478683","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1151930",1975,"Altered sexual development in male rats after oestrogen administration during the neonatal period.","1151930","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1154993",1975,"Effect of sex steroids on the male reproductive organs of the monitor lizard Varanus monitor (Linn.).","1154993","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"11803558",2002,"17 beta-estradiol induces spermatogonial proliferation through mitogen-activated protein kinase (extracellular signal-regulated kinase 1/2) activity in the lizard (Podarcis s. sicula).","11803558","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"11964216",2002,"Seminal plasma melatonin and gonadal steroids concentrations in normal men.","11964216","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"12108785",2002,"Effect of compound CDRI 84/35 and synthetic estrogen on the seminiferous epithelium of immature rat.","12108785","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1218902",1975,"Effect of steroids on the spermatogenesis in the frog Rana hexadactyla lesson.","1218902","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"12193375",2002,"Differential alteration of the reproductive axis by testosterone and estrogen in peripubertal and adult male Siberian hamsters (Phodopus sungorus).","12193375","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"12211062",2002,"Effects of the aromatase inhibitor fadrozole on plasma sex steroid secretion, spermatogenesis and epididymis morphology in the lizard, Podarcis sicula.","12211062","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1222901",1975,"The effect of 17 beta-estradiol acetate on the testis and thumb pad of Rana cyanophlyctis (Schn.) and Rana tigrina (Daud.).","1222901","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1223260",1975,"[Reproductive cycle of trout and tench: effect of experimental variations of the temperature (author's transl)].","1223260","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"12239125",2002,"Estrogen accelerates gonadal recrudescence in photo-regressed male siberian hamsters.","12239125","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1237414",1975,"Pituitary and gonadal hormones in patients with varicocele.","1237414","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"12388134",2003,"Disruption of pubertal onset by exogenous testosterone and estrogen in two species of rodents.","12388134","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"12524017",2003,"Effects of octylphenol and 17beta-estradiol on the gonads of guppies (Poecilia reticulata) exposed as adults via the water or as embryos via the mother.","12524017","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1276318",1976,"The effects of 17 beta-estradiol and medroxyprogesterone acetate alone and in combination with alpha-chlorohydrin on reproductive function in the male rat.","1276318","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"12814350",2003,"Inhibition of the basal and oestradiol-stimulated mitotic activity of primary spermatogonia by melatonin in the testis of the frog, Rana esculenta, in vivo and in vitro.","12814350","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"12840815",2003,"Degree of sex reversal as related to plasma steroid levels in genetic female chickens (Gallus domesticus) treated with Fadrozole.","12840815","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1291339",1992,"[Studies on the production rate of estradiol in the testis in male infertility--studies of the predictive values on therapeutic efficacy in patients with oligozoospermia].","1291339","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"12959643",2003,"The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy.","12959643","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"14555199",2003,"Male reproductive effects of octylphenol and estradiol in Fischer and Wistar rats.","14555199","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1459628",1992,"Differential response of testis and serum gonadotropins to testosterone in rats treated with a gonadotropin releasing hormone antagonist or estradiol 17 beta.","1459628","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"14636640",2003,"Effects of steroid hormones on spermatogenesis and GnRH release in male Leopard frogs, Rana pipiens.","14636640","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"15159111",2004,"Improvement in spermatogenic function after subcutaneous implantation of a capsule containing an aromatase inhibitor in four oligozoospermic dogs and one azoospermic dog with high plasma estradiol-17beta concentrations.","15159111","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"15205377",2004,"Effects of medroxyprogesterone and estradiol on the recovery of spermatogenesis in irradiated rats.","15205377","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"15350809",2004,"Dose- and photoperiod-dependent effects of 17beta-estradiol and the anti-estrogen ICI 182,780 on testicular structure, acceleration of spermatogenesis, and aromatase immunoexpression in immature bank voles.","15350809","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"15501383",2004,"Effects of neonatal administration of 17beta-estradiol, beta-estradiol 3-benzoate, or bisphenol A on mouse and rat spermatogenesis.","15501383","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"15642123",2005,"Alteration of the hypothalamic-pituitary-gonadal axis in estrogen- and androgen-treated adult male leopard frog, Rana pipiens.","15642123","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"15922805",2005,"Sexual behavior and impregnation success of adult male mosquitofish following exposure to 17beta-estradiol.","15922805","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"15930179",2005,"Oestrogen does not affect the restoration of spermatogenesis in the gonadotrophin-releasing hormone-immunised adult rat.","15930179","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"15936871",2005,"Effect of high intratesticular estrogen on the seminiferous epithelium in adult male rats.","15936871","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"16002344",2005,"Effects of selected xenoestrogens on liver peroxisomes, vitellogenin levels and spermatogenic cell proliferation in male zebrafish.","16002344","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"16078662",2005,"[Influence of estradiol benzoate on the testis development of rats].","16078662","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"16176578",2005,"Neonatal androgenization of hypogonadal (hpg) male mice does not abolish estradiol-induced FSH production and spermatogenesis.","16176578","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"16264094",2005,"Estrogenic induction of spermatogenesis in the hypogonadal (hpg) mouse: role of androgens.","16264094","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"16313069",2005,"Effect of estradiol on expression of cytoskeletal proteins during spermatogenesis in testis of sexually mature rats.","16313069","Estradiol","Spermatogenesis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2372,I2372)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2372,J2372)","v":"Spermatogenesis"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2372,H2372)","v":"16541728"},2005,"[Important functions of estrogens in men--breakthrough in contemporary medicine].","16541728","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"16547407",2006,"Induction of female-to-male sex change in the honeycomb grouper (Epinephelus merra) by 11-ketotestosterone treatments.","16547407","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"1666271",1991,"Morphological effects of the catecholestrogens on cells of the seminiferous tubules of Sprague-Dawley rats.","1666271","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1668899",1991,"Inhibition of fertility in the male mouse by combined androgen-antiandrogen therapy.","1668899","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"16837076",2006,"Effect of 17beta-estradiol on gamete quality and maturation in two salmonid species.","16837076","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"16870949",2006,"Effects of estradiol infusion in GnRH immunized boars on spermatogenesis.","16870949","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"16940288",2006,"17beta-estradiol induces Akt-1 through estrogen receptor-beta in the frog (Rana esculenta) male germ cells.","16940288","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"17017399",2006,"Hormonal contraceptive like effect of estrogen in milk protein-fed male rats.","17017399","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"17050857",2007,"17Beta-estradiol triggers postspawning in spermatogenically active gilthead seabream (Sparus aurata L.) males.","17050857","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1752450",1991,"[Serum concentrations of estradiol and testosterone in patients with oligoasthenozoospermia and asthenozoospermia].","1752450","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"17544424",2008,"Effects of larval exposure to estradiol on spermatogenesis and in vitro gonadal steroid secretion in African clawed frogs, Xenopus laevis.","17544424","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"18061183",2008,"Estrogen regulation of the male reproductive tract in the frog, Rana esculenta: a role in Fra-1 activation in peritubular myoid cells and in sperm release.","18061183","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"18097524",2008,"Maturation, proliferation and apoptosis of seminal tubule cells at puberty after administration of estradiol, follicle stimulating hormone or both.","18097524","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"18230131",2008,"Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg) mouse.","18230131","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"18286211",2008,"Effects of estradiol-17beta and bisphenol A administered chronically to mice throughout pregnancy and lactation on the male pups' reproductive system.","18286211","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"18353327",2008,"Sex change of adult initial-phase male wrasse, Halichoeres trimaculatus by estradiol-17 beta treatment.","18353327","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"18465685",2008,"The effects of cryptorchidism on the regulation of steroidogenesis and gap junctional communication in equine testes.","18465685","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"18566133",2008,"The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line.","18566133","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"19007549",2008,"Oestradiol-induced spermatogenesis requires a functional androgen receptor.","19007549","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"19095743",2009,"Disruption of tubulobulbar complex by high intratesticular estrogens leading to failed spermiation.","19095743","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"19136390",2009,"Estrogen enhances recovery from radiation-induced spermatogonial arrest in rat testes.","19136390","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"19233",1977,"Estradiol binding capacity in the cryptorchid rat testis.","19233","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"1950593",1991,"Effect of estradiol on spermatogenesis and testicular hydroxysteroid dehydrogenase activities in Bidder's organectomized toad (Bufo melanostictus).","1950593","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"19684341",2010,"Assessment of seminal estradiol and testosterone levels as predictors of human spermatogenesis.","19684341","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"19903717",2010,"Induction of spermatogenic cell apoptosis in prepubertal rat testes irrespective of testicular steroidogenesis: a possible estrogenic effect of di(n-butyl) phthalate.","19903717","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"20089883",2010,"Interdependence of platelet-derived growth factor and estrogen-signaling pathways in inducing neonatal rat testicular gonocytes proliferation.","20089883","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"20385159",2010,"Post-hatch oral estrogen in zebra finches (Taeniopygia guttata): is infertility due to disrupted testes morphology or reduced copulatory behavior?","20385159","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"20410197",2010,"Estradiol induction of spermatogenesis is mediated via an estrogen receptor-{alpha} mechanism involving neuroendocrine activation of follicle-stimulating hormone secretion.","20410197","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"2045090",1991,"Behavioral, hormonal, and morphological responses of free-living male pied flycatchers to estradiol treatment of their mates.","2045090","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"204528",1978,"Secretion of proteins by Sertoli cell enriched cultures: effects of follicle stimulating hormone, dibutyryl cAMP and testosterone and correlation with secretion of oestradiol and androgen binding protein.","204528","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"20820944",2011,"Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17?-estradiol level in induction of acute oxidative stress.","20820944","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"20883121",2010,"AR versus ER (?) expression in the testis and pituitary following chronic estrogen administration in adult rat.","20883121","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"21117145",2011,"Role of estrogen in spermatogenesis in initial phase males of the three-spot wrasse (Halichoeres trimaculatus): effect of aromatase inhibitor on the testis.","21117145","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"2117584",1990,"Prolonged suppression of spermatogenesis by oestrogen does not preserve the seminiferous epithelium in procarbazine-treated rats.","2117584","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"21333471",2011,"Early prepubertal testis criteria, seminiferous epithelium and hormone concentrations as related to testicular development in beef bulls.","21333471","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"21535008",2011,"Testosterone and oestradiol in concert protect seminiferous tubule maturation against inhibition by GnRH-antagonist.","21535008","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"21653891",2011,"Estrogen-regulated genes in rat testes and their relationship to recovery of spermatogenesis after irradiation.","21653891","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"21718987",2011,"Apoptosis-inhibitor Aven is downregulated in defective spermatogenesis and a novel estrogen target gene in mammalian testis.","21718987","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"21849707",2011,"Defining the impact of estrogen on spermatogonial fate.","21849707","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"21915674",2011,"Altered phosphorylation and distribution status of vimentin in rat seminiferous epithelium following 17?-estradiol treatment.","21915674","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"22180637",2012,"17?-Estradiol regulates cyclin A1 and cyclin B1 gene expression in adult rat seminiferous tubules.","22180637","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"22860010",2012,"Proteomic changes in rat spermatogenesis in response to in vivo androgen manipulation; impact on meiotic cells.","22860010","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"22898016",2012,"Testicular testosterone: estradiol ratio in domestic cats and its relationship to spermatogenesis and epididymal sperm morphology.","22898016","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"22999797",2013,"Clomiphene citrate potentiates the adverse effects of estrogen on rat testis and down-regulates the expression of steroidogenic enzyme genes.","22999797","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"23220551",2013,"Regulation of apoptotic signaling pathways by 5?-dihydrotestosterone and 17?-estradiol in immature rat Sertoli cells.","23220551","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"23283575",2013,"Cyp17a1 and Cyp19a1 in the zebrafish testis are differentially affected by oestradiol.","23283575","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"23677985",2013,"Low 17beta-estradiol levels in CNR1 knock-out mice affect spermatid chromatin remodeling by interfering with chromatin reorganization.","23677985","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"23788033",2013,"Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity.","23788033","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"24011196",2013,"Estradiol and testosterone inhibit rat seminiferous tubule development in a hormone-specific way.","24011196","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"2566621",1989,"Improvement of spermatogenesis after treatment with the antiestrogen tamoxifen in a man with the incomplete androgen insensitivity syndrome.","2566621","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"3026395",1986,"Possible involvement of germ cells in the regulation of oestradiol-17 beta and ABP secretion by immature rat Sertoli cells (in vitro studies).","3026395","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"3083663",1986,"[Effects of etretinate on spermatogenesis and endocrine parameter function in man].","3083663","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"3088806",1986,"[Fluctuation in the concentration of sex steroids and aflatoxin B1 in the seminal plasma of boars and its relation to sperm production].","3088806","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"3134781",1987,"Demonstration of direct effect of estrogen on rat spermatogenesis.","3134781","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"3240941",1988,"Quantitative analysis of spermatogonial germ cells in adult rats treated with oestradiol benzoate alone &amp; in combination with testosterone propionate.","3240941","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"3360185",1988,"Concentrations of estradiol in serum and testis tissue in patients with fertility disorders.","3360185","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"3375504",1988,"Estimation of human reproductive risk from animal studies: determination of interspecies extrapolation factors for steroid hormone effects on the male.","3375504","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"3676392",1987,"Effect of estradiol-filled polydimethylsiloxane subdermal implants in adult male rats on the reproductive system, fertility, and progeny outcome.","3676392","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4007474",1985,"[Plasma androgens and 17 beta-estradiol of the Pyrenean urodele Euproctus asper during the period of reproduction].","4007474","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"40899",1978,"Possible effects of ovocyclin in male reproduction.","40899","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"4152351",1973,"[Growth and structure of cryptorchid testes in mice born of mothers treated by oestradiol during pregnancy (author's transl)].","4152351","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"4267410",1973,"Toxicity in beagle dogs of three alkylating esters with antitumor activity: phenesterin (NSC-104469), estradiol mustard (NSC-112259), and dehydroepiandrosterone mustard (NSC-12121).","4267410","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4282052",1974,"[In vitro culture of the hermaphrodite gland of the snail helix aspersa in the presence of steroids].","4282052","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4359981",1971,"Effect of oestradiol-3,17beta dipropionate on spermatogenesis and lysosomal enzymes in the rat testis.","4359981","Estradiol","Spermatogenesis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2436,I2436)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2436,J2436)","v":"Spermatogenesis"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2436,H2436)","v":"4405594"},1972,"[Comparative study of changes in gonadotropic cells and testis in male rats treated with estrogens during the neonatal period].","4405594","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"4426307",1974,"Ultrastructural changes in the testis of mice given neonatal injections of estrogen.","4426307","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4430442",1974,"Effects of testosterone and oestradiol on gonadectomized and intact male and female river lampreys (Lampetra fluviatilis (L.) Gray).","4430442","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4463806",1974,"[Proceedings: Sexual behavior and genital tract of adult male rats previously treated by estrogens in the early neonatal stage (author's transl)].","4463806","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4536880",1972,"Neonatal sterilization of rodents with steroid hormones. 4. The influence of estradiol benzoate injected into five day old male rats on the weight of testes and ventral prostate and histology of the seminiferous epithelium and the pituitary gland during sexual maturation.","4536880","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4678850",1972,"Inhibitory effect of androgen on induction of permanent changes in the testis by neonatal injections of estrogen in mice.","4678850","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4678851",1972,"Effects of gonadotropins on the occurrence of permanent changes in the testis of mice given neonatal estrogen injections.","4678851","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4716418",1973,"The normal development of the blood-testis barrier and the effects of clomiphene and estrogen treatment.","4716418","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4724755",1973,"Testes of roosters treated with a single dose of estradiol dipropionate.","4724755","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4751822",1973,"Plasma testosterone, estradiol, and semen analysis in male homosexuals.","4751822","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4778697",1973,"[The effect of unilateral castration on the testes of mature rats receiving repeated injections of estradiol-propionate].","4778697","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"4812464",1974,"Effects of testosterone and follicle-stimulating hormone on spermatogenesis in adult mice during treatment with oestradiol.","4812464","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",1,1,"485634",1979,"Effects of estradiol-17 beta on reproduction in adult male rats.","485634","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"486667",1979,"Interactions of testosterone and estradiol-17 beta on the reproductive tract of the male rat.","486667","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"57575",1976,"Protection of spermatogenesis by alpha2u globulin in rats treated with oestrogen.","57575","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"6186760",1983,"Effect of alpha 2u-globulin on serum concentration of gonadotrophins and testicular activity in oestrogen-treated rats.","6186760","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"6721122",1984,"[Hormonal studies in patients with idiopathic varicocele].","6721122","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"6733210",1984,"Comparison of the effects of gossypol, estradiol-17 beta and testosterone compensation on male rat reproductive organs.","6733210","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"6772248",1980,"Effects of intranasal administration of hormonal steroids on serum testosterone and spermatogenesis in rhesus monkey (Macaca mulatta).","6772248","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"6833460",1983,"Human chorionic gonadotropin and testicular function: stimulation of testosterone, testosterone precursors, and sperm production despite high estradiol levels.","6833460","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"6851565",1983,"Somatic tissue responses of male rhesus monkeys treated with a contraceptive steroid formulation.","6851565","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"7045269",1982,"Initiation of spermatogenesis and testicular growth in oestradiol-17 beta-implanted bull calves with pulsatile infusion of luteinizing hormone releasing hormone.","7045269","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"7118204",1982,"Effect of estradiol-17 beta, estradiol-17 beta + homoplastic pars distalis extract, estradiol-17 beta + testosterone &amp; testosterone on spermatogenesis, Leydig cells &amp; thumb pads in the toad Bufo melanostictus (Schn.).","7118204","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"7122318",1982,"Effects of cyproterone acetate and oestradiol benzoate on the rat testis. Morphometric study after treatment over 35 days.","7122318","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"719098",1978,"Recovery of testicular and pituitary functions in adult male rats after cessation of short and long term estradiol treatment.","719098","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"7422674",1980,"Long-term effects of neonatal administration of estrogen and progesterone, alone or in combination, on male BALB/c and BALB/cfC3H mice.","7422674","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"7431312",1980,"Gonadotrophin-induced reinitiation of meiosis in testes of oestradiol-treated prepubertal rats.","7431312","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"746885",1978,"[Testicular action of estrogens and antiandrogens--karyo-, histometric and histochemical studies of dog testis].","746885","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"7702871",1995,"Effect of estradiol and progesterone on c-myc expression in the sea star testis and the seasonal regulation of spermatogenesis.","7702871","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"7929722",1994,"Serum luteinizing hormone pulsatility and intratesticular testosterone and oestradiol concentrations in idiopathic infertile men with high and normal follicle stimulating hormone serum concentrations.","7929722","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"801317",1976,"[The histological modifications of genital system of oestradiol benzoate treated male rats (author's transl)].","801317","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"8016314",1994,"Protection from radiation-induced damage to spermatogenesis by hormone treatment.","8016314","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"8070709",1994,"[Comparison between the influence of estradiol benzoate, testosterone propionate and human chorionic gonadotropin on initiation of spermatogenesis in the rat].","8070709","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"8070710",1994,"[Tamoxifen and spermatogenesis in rats subjected to effects of estradiol].","8070710","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"8226305",1993,"Protection by gonadal steroid hormones against procarbazine-induced damage to spermatogenic function in LBNF1 hybrid rats.","8226305","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"864656",1977,"Spermatogenesis in hybrid mice treated with oestrogen and testosterone.","864656","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"8706156",1995,"[Protection from procarbazine induced testicular toxicity by gonadal steroid hormones].","8706156","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"8756553",1996,"Relationship among hormonal treatments, suppression of spermatogenesis, and testicular protection from chemotherapy-induced damage.","8756553","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"8760854",1996,"Further observations on the early events that contribute to establishing the morphological pattern shown by the oestradiol suppressed testis.","8760854","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"8775062",1995,"Stimulation of spermatogenesis or of sex reversal according to the dose of exogenous estradiol-17 beta in juvenile males of protandrous black porgy, Acanthopagrus schlegeli.","8775062","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"8930608",1996,"Effect of 17 beta-estradiol, testosterone, and 11-ketotestosterone on 17,20 beta-dihydroxy-4-pregnen-3-one production in the rainbow trout testis.","8930608","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"8966101",1996,"[Precocious maturation of the testis associated with excessive secretion of estradiol and testosterone by Leydig cells].","8966101","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"9067277",1997,"Protection from procarbazine-induced testicular damage by hormonal pretreatment does not involve arrest of spermatogonial proliferation.","9067277","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"909588",1977,"Synergistic interaction of testosterone and oestradiol inhibits spermatogenesis in rats.","909588","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"9649919",1998,"Tamoxifen-induced light and electron microscopic changes in the rat testicular morphology and serum hormonal profile of reproductive hormones.","9649919","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"9675620",1998,"Apoptosis precedes detachment of germ cells from the seminiferous epithelium after hormone suppression by short-term oestradiol treatment of rats.","9675620","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogenesis",0,1,"9737741",1998,"Neonatal exposure of male rats to estradiol benzoate causes rete testis dilation and backflow impairment of spermatogenesis.","9737741","Estradiol","Spermatogenesis",1,null,1]
["Estradiol","Spermatogonia",0,1,"10385420",1999,"c-fos activity in Rana esculenta testis: seasonal and estradiol-induced changes.","10385420","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"10527870",1999,"Estradiol-17beta stimulates the renewal of spermatogonial stem cells in males.","10527870","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"11014502",2000,"Effects of sex steroid hormones and their antagonists on mast cell number in the testis of the frog, Rana esculenta.","11014502","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"11803558",2002,"17 beta-estradiol induces spermatogonial proliferation through mitogen-activated protein kinase (extracellular signal-regulated kinase 1/2) activity in the lizard (Podarcis s. sicula).","11803558","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"15139905",2004,"Effects of the wood extractive betulinol and 17beta-oestradiol on reproduction in zebrafish, Danio rerio (Hamilton)--complications due to a bacterial infection.","15139905","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"15205377",2004,"Effects of medroxyprogesterone and estradiol on the recovery of spermatogenesis in irradiated rats.","15205377","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"15862016",2005,"[Relationship between spermatogenic cell apoptosis and serum estradiol level in rats exposed to fluoride].","15862016","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"17050857",2007,"17Beta-estradiol triggers postspawning in spermatogenically active gilthead seabream (Sparus aurata L.) males.","17050857","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"17712483",2007,"17beta-estradiol stimulates proliferation of spermatogonia in experimental cryptorchid mice.","17712483","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"18566133",2008,"The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line.","18566133","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"19136390",2009,"Estrogen enhances recovery from radiation-induced spermatogonial arrest in rat testes.","19136390","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"19420009",2009,"Oestrogen-induced androgen insufficiency results in a reduction of proliferation and differentiation of spermatogonia in the zebrafish testis.","19420009","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"20089883",2010,"Interdependence of platelet-derived growth factor and estrogen-signaling pathways in inducing neonatal rat testicular gonocytes proliferation.","20089883","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"2740369",1989,"Transient effect of daily injection of estrogen on spermatogonial mitosis in the rat.","2740369","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"3240941",1988,"Quantitative analysis of spermatogonial germ cells in adult rats treated with oestradiol benzoate alone &amp; in combination with testosterone propionate.","3240941","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"3351446",1988,"Evidence for the sexual bipotentiality of spermatogonia in the fish, Oryzias latipes.","3351446","Estradiol","Spermatogonia",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2500,I2500)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2500,J2500)","v":"Spermatogonia"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2500,H2500)","v":"6534846"},1984,"Cell generation cycle of spermatogonia in immature rats treated neonatally with oestrogen.","6534846","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"7122318",1982,"Effects of cyproterone acetate and oestradiol benzoate on the rat testis. Morphometric study after treatment over 35 days.","7122318","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"8016314",1994,"Protection from radiation-induced damage to spermatogenesis by hormone treatment.","8016314","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"8706156",1995,"[Protection from procarbazine induced testicular toxicity by gonadal steroid hormones].","8706156","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"9067277",1997,"Protection from procarbazine-induced testicular damage by hormonal pretreatment does not involve arrest of spermatogonial proliferation.","9067277","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"9143141",1997,"17 beta-estradiol effects on mast cell number and spermatogonial mitotic index in the testis of the frog, Rana esculenta.","9143141","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatogonia",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Estradiol","Spermatogonia",1,null,1]
["Estradiol","Spermatozoa",0,1,"10365314",1999,"Role of estradiol in the capacitation and acrosome reaction of hamster epididymal spermatozoa in the isolated uterus of mice incubated in vitro.","10365314","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"10525362",1999,"The effect of estrogen on the gonads and on in vitro conversion of androstenedione to testosterone, 11-ketotestosterone, and estradiol-17beta in Sparus aurata (Teleostei, Sparidae).","10525362","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"10565435",1999,"Effects of 17beta-oestradiol or oestrous stage-specific cow serum on the ability of bovine oviductal epithelial cell monolayers to prolong the viability of bull spermatozoa.","10565435","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",1,1,"10686218",2000,"Oestradiol enhances testosterone-induced suppression of human spermatogenesis.","10686218","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"10843196",2000,"Estradiol acts as a germ cell survival factor in the human testis in vitro.","10843196","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"10869566",2000,"Dual regulation of the T-type Ca(2+) current by serum albumin and beta-estradiol in mammalian spermatogenic cells.","10869566","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"11014502",2000,"Effects of sex steroid hormones and their antagonists on mast cell number in the testis of the frog, Rana esculenta.","11014502","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"11028926",2000,"Surrogate pregnancies in patients with Mayer-Rokitansky-Kustner-Hauser syndrome and severe teratozoospermia.","11028926","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"11800162",2001,"The influence of estrogen on the developing male marsupial.","11800162","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"1195247",1975,"17-Hydroxyandrogens and oestrogens in the plasma of normal and infertile men.","1195247","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"11964215",2002,"Induction of nuclear matrix-estradiol receptor complex during capacitation process in human spermatozoa.","11964215","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"11964216",2002,"Seminal plasma melatonin and gonadal steroids concentrations in normal men.","11964216","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"12018935",2002,"Variation in plasma steroids and reproductive traits in dimorphic males of corkwing wrasse (Symphodus melops L.).","12018935","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"12108785",2002,"Effect of compound CDRI 84/35 and synthetic estrogen on the seminiferous epithelium of immature rat.","12108785","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,0,"12265605",1978,"Hypogonadism in chronically lead-poisoned men.","12265605","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,0,"12341905",1987,"Effects of estradiol and its antagonist tamoxifen on motility and metabolism of human spermatozoa.","12341905","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"1238386",1975,"Improvement of sperm transport by the administration of estradiol to estrous ewes.","1238386","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"12525448",2003,"17beta-Estradiol and environmental estrogens significantly affect mammalian sperm function.","12525448","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"12713430",2003,"Effect of intrauterine insemination with spermatozoa or foreign protein on the mechanism of action of oestradiol in the rat oviduct.","12713430","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"1276318",1976,"The effects of 17 beta-estradiol and medroxyprogesterone acetate alone and in combination with alpha-chlorohydrin on reproductive function in the male rat.","1276318","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"12814350",2003,"Inhibition of the basal and oestradiol-stimulated mitotic activity of primary spermatogonia by melatonin in the testis of the frog, Rana esculenta, in vivo and in vitro.","12814350","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"12840815",2003,"Degree of sex reversal as related to plasma steroid levels in genetic female chickens (Gallus domesticus) treated with Fadrozole.","12840815","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,0,"13389986",1956,"[Estrogen shock in the treatment of seminal deficiency].","13389986","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,0,"14032798",1963,"Effect of estradiol benzoate treatment in the newborn male rat.","14032798","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,0,"14111321",1964,"[THE MECHANISM OF ACTION OF PROGESTATIONAL HORMONES IN THE ANTI-MASCULINE EFFECT ON FETAL RATS].","14111321","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,0,"14150606",1964,"EFFECTS OF CERTAIN HORMONES ON THE METABOLISM OF BULL SPERMATOZOA.","14150606","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,0,"14211908",1964,"CONVERSION OF 17-BETA-ESTRADIOL TO ESTRONE BY SPERMATOZOA OF DOGS AND MEN.","14211908","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,0,"14217700",1964,"[STEROIDS IN HORSE SPERM].","14217700","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,0,"14301526",1965,"EFFECT OF ESTROGEN OR TESTOSTERONE ON INITIATION AND MAINTENANCE OF SPERMATOGENESIS IN THE RAT.","14301526","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,0,"14427866",1959,"The endocrine control of the passage of spermatozoa and ova through the female genital tract.","14427866","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"14613549",2003,"The antiestrogen ICI 182,780 decreases the expression of estrogen receptor-alpha but has no effect on estrogen receptor-beta and androgen receptor in rat efferent ductules.","14613549","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"14648872",2004,"Toxicogenomic difference between diethylstilbestrol and 17beta-estradiol in mouse testicular gene expression by neonatal exposure.","14648872","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"14709824",2003,"Therapeutic effect of aromatase inhibitor in two azoospermic dogs with high plasma estradiol-17beta levels.","14709824","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"15226595",2004,"Effects of 17beta-estradiol on in vitro maturation of pig oocytes in protein-free medium.","15226595","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",1,1,"15501383",2004,"Effects of neonatal administration of 17beta-estradiol, beta-estradiol 3-benzoate, or bisphenol A on mouse and rat spermatogenesis.","15501383","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"15545282",2005,"Estrogen-induced spermatogenic cell apoptosis occurs via the mitochondrial pathway: role of superoxide and nitric oxide.","15545282","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"15819956",2005,"The effect of oestradiol, progesterone and heparin on bovine spermatozoa function after thawing.","15819956","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",1,1,"15848257",2005,"Plasma concentrations of estradiol and testosterone, gonadal aromatase activity and ultrastructure of the testis in Xenopus laevis exposed to estradiol or atrazine.","15848257","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"16078571",2005,"[Effects of estrogen on acrosome reaction and intracellular calcium in human spermatozoa and the possible mechanism concerned].","16078571","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"16313069",2005,"Effect of estradiol on expression of cytoskeletal proteins during spermatogenesis in testis of sexually mature rats.","16313069","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"16707209",2006,"Estradiol affects androgen-binding protein expression and fertilizing ability of spermatozoa in adult male rats.","16707209","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",1,1,"16723207",2006,"The effect of estrogen on testicular gonocyte maturation.","16723207","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"16830234",2006,"Estradiol treatment induces testicular oxidative stress and germ cell apoptosis in rats.","16830234","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"16940288",2006,"17beta-estradiol induces Akt-1 through estrogen receptor-beta in the frog (Rana esculenta) male germ cells.","16940288","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",1,1,"1719410",1991,"Testicular toxicity and mutagenicity of steroidal and non-steroidal estrogens in the male mouse.","1719410","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"17506812",2007,"Effect of progesterone and oestradiol on sperm-zona binding and acrosome reaction in bovine spermatozoa after thawing.","17506812","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",1,1,"17569695",2007,"Developmental changes in testicular sensitivity to estrogens throughout fetal and neonatal life.","17569695","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"17915450",2007,"[Male infertility in delay of sexual development].","17915450","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"18061183",2008,"Estrogen regulation of the male reproductive tract in the frog, Rana esculenta: a role in Fra-1 activation in peritubular myoid cells and in sperm release.","18061183","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"18097524",2008,"Maturation, proliferation and apoptosis of seminal tubule cells at puberty after administration of estradiol, follicle stimulating hormone or both.","18097524","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"18292837",2007,"During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.","18292837","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"18353327",2008,"Sex change of adult initial-phase male wrasse, Halichoeres trimaculatus by estradiol-17 beta treatment.","18353327","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"18359755",2008,"Serum concentrations of estradiol and free T4 are inversely correlated with sperm DNA damage in men from an infertility clinic.","18359755","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"18477200",2008,"Physiological action of oestradiol on the acrosome reaction in human spermatozoa.","18477200","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"1860676",1991,"[Inhibin, steroid hormone, and gonadotropin concentration in blood from fertile and infertile males and its relationship with testicular function].","1860676","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"19007549",2008,"Oestradiol-induced spermatogenesis requires a functional androgen receptor.","19007549","Estradiol","Spermatozoa",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2564,I2564)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2564,J2564)","v":"Spermatozoa"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2564,H2564)","v":"19171371"},2009,"Effects of 17beta-estradiol, and its metabolite, 4-hydroxyestradiol on fertilization, embryo development and oxidative DNA damage in sand dollar (Dendraster excentricus) sperm.","19171371","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",1,1,"19292035",2009,"[Effects of prepubertal exposure to estradiol benzoate on testicular development and function of Sprague-Dawley rats].","19292035","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"19950600",2009,"[Mechanisms of nongenomic effect of 17beta-estradiol on human spermatozoa].","19950600","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"19996653",2009,"Role of testosterone/estradiol ratio in predicting the efficacy of tamoxifen citrate treatment in idiopathic oligoasthenoteratozoospermic men.","19996653","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"2011591",1991,"Sperm attraction to a follicular factor(s) correlates with human egg fertilizability.","2011591","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"20562298",2010,"Suppression of progesterone-enhanced hyperactivation in hamster spermatozoa by estrogen.","20562298","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"22732148",2012,"Does last week's alcohol intake affect semen quality or reproductive hormones? A cross-sectional study among healthy young Danish men.","22732148","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"22898016",2012,"Testicular testosterone: estradiol ratio in domestic cats and its relationship to spermatogenesis and epididymal sperm morphology.","22898016","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"23220551",2013,"Regulation of apoptotic signaling pathways by 5?-dihydrotestosterone and 17?-estradiol in immature rat Sertoli cells.","23220551","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"23319664",2013,"In vivo exposure to 17?-estradiol triggers premature sperm capacitation in cauda epididymis.","23319664","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"2358078",1990,"Serum hormone levels affect sperm function.","2358078","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"2374426",1990,"Effect of Allium sativum on epididymal spermatozoa, estradiol-treated mice and general toxicity.","2374426","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"23904510",2013,"In vitro mimicking of estrous cycle stages in porcine oviduct epithelium cells: estradiol and progesterone regulate differentiation, gene expression, and cellular function.","23904510","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"24011196",2013,"Estradiol and testosterone inhibit rat seminiferous tubule development in a hormone-specific way.","24011196","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"24065277",2013,"Female sex hormones regulate the Th17 immune response to sperm and Candida albicans.","24065277","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"24499511",2014,"Alterations in the estrogen environment of the testis contribute to declining sperm production in aging rats.","24499511","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"2497096",1989,"Indomethacin and oxaprozin lower seminal prostaglandin levels but do not influence sperm motion characteristics and serum hormones of young healthy men in a placebo-controlled double-blind trial.","2497096","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"2740369",1989,"Transient effect of daily injection of estrogen on spermatogonial mitosis in the rat.","2740369","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"2757457",1989,"Stimulation of motility and energy metabolism of spermatozoa from asthenozoospermic patients by 17 beta-estradiol.","2757457","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"3240941",1988,"Quantitative analysis of spermatogonial germ cells in adult rats treated with oestradiol benzoate alone &amp; in combination with testosterone propionate.","3240941","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"3351446",1988,"Evidence for the sexual bipotentiality of spermatogonia in the fish, Oryzias latipes.","3351446","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4127001",1973,"Steroid hormones and the fertilizing capacity of spermatozoa.","4127001","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4193640",1970,"Inhibition of sperm capacitation in vitro by contraceptive steroids.","4193640","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4286158",1965,"Conversion of estradiol-17-beta by sperm preparations of sea urchins and oysters.","4286158","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4328780",1970,"Bull seminal plasma and the regulation of 17-beta-estradiol dehydrogenase activity in spermatozoa.","4328780","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4363158",1974,"Long-term therapy with low-dose cisclomiphene in male infertility: effects on semen, serum FSH, LH, testosterone ond estradiol, and carbohydrate tolerance.","4363158","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4377735",1974,"[The influence of demonstrated sex steroids and cyclic adenosine-3'-5'-monophosphate in human cervix mucus on sperm metabolism and capacitation].","4377735","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4407895",1974,"Sperm distribution in female rabbits: the effect of ovarian steroids.","4407895","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4408369",1974,"Tetracycline and steroid hormone binding to human spermatozoa.","4408369","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4597757",1974,"The inhibition of fertilizing ability of epididymal spermatozoa by the administration of oestradiol benzoate to testosterone-maintained hypophysectomized or castrated hamsters.","4597757","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4742008",1973,"Fertilizing ability of hamster spermatozoa following subcutaneous implantation or insertion into seminal vesicles of silastic tubes containing estradiol benzoate.","4742008","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4751822",1973,"Plasma testosterone, estradiol, and semen analysis in male homosexuals.","4751822","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4812464",1974,"Effects of testosterone and follicle-stimulating hormone on spermatogenesis in adult mice during treatment with oestradiol.","4812464","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"4833557",1974,"Oxidative metabolism of chicken semen and washed spermatozoa in the presence of various steroid hormones.","4833557","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"485657",1979,"Binding of 17-beta-estradiol to the outer surface and nucleus of human spermatozoa.","485657","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"486667",1979,"Interactions of testosterone and estradiol-17 beta on the reproductive tract of the male rat.","486667","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"50446",1975,"The effect of oestrogen administered during the progestational phase of the cycle on transport of spermatozoa in ewes.","50446","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"5050147",1972,"Effect of testosterone, estradiol-17-beta and progesterone on the oxygen uptake by bovine semen, washed spermatozoa and epididymal-like spermatozoa.","5050147","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"5091295",1971,"Comparison of the effects of cyproterone, cyproterone acetate and oestradiol on testicular function, accessory sexual glands and fertility in a long-term study on rats.","5091295","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"5359074",1969,"Effect of estrogen on survival of spermatozoa in the genital tract of castrated male rats.","5359074","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"5465782",1970,"Effects of various progestins and estrogen on the gamete transport and fertilization in the rabbit.","5465782","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"5537134",1970,"Testicular damages in neonatally estrogenized adult mice.","5537134","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"5629426",1967,"[On endocrine conditioning and resorption of spermatozoids by the female genital passages in golden hamsters (Mesocricetus auratus Waterhouse)].","5629426","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"566749",1978,"Number of sperm in the oviducts, uterus, and cervix of the mated ewe as affected by exogenous estradiol.","566749","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"5718720",1968,"Effect of hormones on gonads of sterile hybrid ducks.","5718720","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"5793461",1969,"Testicular development in rats treated with several steroids shortly after birth.","5793461","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",1,1,"5843079",1965,"Changes in the epididymis associated with morphological changes in the spermatozoa.","5843079","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"5891512",1965,"[Changes of seminal epithelium following repeated doses of estradiol. Investigations on the rat testis].","5891512","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"5950607",1966,"Cyclic changes of cervical mucus in normal and progestin-treated women.","5950607","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"598880",1977,"In vitro effect of steroids on the enzyme release from bovine spermatozoa.","598880","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6030761",1967,"Specificity of testosterone and estradiol in the differentiating neonatal rat.","6030761","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6050510",1967,"Effect of estradiol-17-beta on the distribution of 3-beta-hydroxysteroid dehydrogenase in the testes of Rana esculenta and Lacerta sicula.","6050510","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6055312",1967,"Influence of gonadal hormones and leukocytes on sperm removal from the rat uterus.","6055312","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6072462",1967,"Binding of sex steroids to rabbit sperm.","6072462","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6148324",1984,"Altered structural and functional integrity of the reproductive tissues in estradiol benzoate-treated intact male albino rats.","6148324","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"620698",1978,"Effects of some steroid hormones on head-to-head association in bovine spermatozoa.","620698","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6431658",1984,"Endocrine profile and seminal plasma composition in Hansen's disease.","6431658","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6534846",1984,"Cell generation cycle of spermatogonia in immature rats treated neonatally with oestrogen.","6534846","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"656527",1978,"Estrogens in the seminal vesicle fluid and the effect of exogenous estradiol-17beta on hormonal profile in the male rat.","656527","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6658892",1983,"Steroid metabolism by monkey and human spermatozoa.","6658892","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6685463",1983,"Effect of steroid hormones on membrane sugar transport in human spermatozoa.","6685463","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6756866",1982,"[Distribution of sperm cells in the female genital tract of rabbits. I. Effect of LH-RH and 17 beta-estradiol].","6756866","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6848394",1983,"Stimulation of the zona-free hamster ova penetration efficiency by human spermatozoa after 17 beta-estradiol treatment.","6848394","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"6851566",1983,"Contraceptive efficacy of testosterone-estradiol implants in male rhesus monkeys.","6851566","Estradiol","Spermatozoa",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2628,I2628)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2628,J2628)","v":"Spermatozoa"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2628,H2628)","v":"690978"},1978,"The metabolism and motility of human spermatozoa in the presence of steroid hormones and synthetic progestagens.","690978","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"694966",1978,"The effect of the administration of spironolactone on the concentration of plasma testosterone, estradiol and cortisol in male dogs (1).","694966","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"7203688",1981,"The binding of sex steroids to human spermatozoa. An autoradiographic study.","7203688","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"7263087",1981,"The binding of oestradiol-17beta to human spermatozoa - an electron microscope autoradiographic study.","7263087","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"7309138",1981,"Effect of exogenous testosterone, estradiol &amp; progesterone on oxidative &amp; glycolytic metabolism of buffalo spermatozoa.","7309138","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"7388109",1980,"Failure of estrogen administered to adult rats to suppress meiotic DNA synthesis and differentiation of spermatocytes.","7388109","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"8226305",1993,"Protection by gonadal steroid hormones against procarbazine-induced damage to spermatogenic function in LBNF1 hybrid rats.","8226305","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"8498869",1993,"Concentrations of intracellular sex steroids in human spermatozoa.","8498869","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"8579846",1995,"Capacitation in vitro of bovine spermatozoa by oviduct epithelial cell monolayer conditioned medium.","8579846","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",1,1,"8667451",1995,"Collaborative work to determine the optimal administration period and parameters to detect drug effects on male rat fertility--study on estradiol benzoate effects.","8667451","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"8760854",1996,"Further observations on the early events that contribute to establishing the morphological pattern shown by the oestradiol suppressed testis.","8760854","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"8940662",1996,"Induction of apoptotic cell death in the seminiferous tubule of the adult rat testis: assessment of the germ cell types that exhibit the ability to enter apoptosis after hormone suppression by oestradiol treatment.","8940662","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"907208",1977,"Some interrelationships between plasma levels of LH, FSH, oestradiol 17beta, androgens and semen analysis data in male infertility patients.","907208","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"908587",1977,"Effect of estradiol-17beta &amp; estriol-3-methyl ether on spermatozoa &amp; genital organs of rats.","908587","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"9208651",1996,"[The antifertility effect of gossypol plus testosterone and estrogen].","9208651","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"9227358",1997,"Apoptosis pattern elicited by oestradiol treatment of the seminiferous epithelium of the adult rat.","9227358","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"924007",1977,"The metabolism and motility of human spermatozoa in the presence of steroid hormones and synthetic progestagens.","924007","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"9367715",1997,"Effects of estradiol-17beta and progesterone on mating behavior in female lesser bushbabies (Galago moholi) in captivity.","9367715","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"9675620",1998,"Apoptosis precedes detachment of germ cells from the seminiferous epithelium after hormone suppression by short-term oestradiol treatment of rats.","9675620","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"986848",1976,"Improvement of sperm transport in estrous rabbits by exogenous estradiol.","986848","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Spermatozoa",0,1,"992755",1976,"Influence of testosterone &amp; estradiol-17beta on the spermatozoa &amp; accessory genital organs of castrated rats.","992755","Estradiol","Spermatozoa",1,null,1]
["Estradiol","Testicular Neoplasms",0,1,"12443684",2002,"Blood plasma concentrations of oestradiol-17beta, testosterone and testosterone/oestradiol ratio in dogs with neoplastic and degenerative testicular diseases.","12443684","Estradiol","Testicular Neoplasms",1,null,1]
["Estradiol","Testicular Neoplasms",0,0,"14161068",1963,"STUDIES ON THE URINARY STEROIDS IN BILATERAL GYNECOMASTIA.","14161068","Estradiol","Testicular Neoplasms",1,null,1]
["Estradiol","Testicular Neoplasms",0,1,"16882463",2007,"Maternal hormone levels and perinatal characteristics: implications for testicular cancer.","16882463","Estradiol","Testicular Neoplasms",1,null,1]
["Estradiol","Testicular Neoplasms",0,1,"19037884",2009,"Use of intralesional oestradiol concentration to identify a functional pulmonary metastasis of canine sertoli cell tumour.","19037884","Estradiol","Testicular Neoplasms",1,null,1]
["Estradiol","Testicular Neoplasms",0,1,"3458941",1986,"Higher maternal levels of free estradiol in first compared to second pregnancy: early gestational differences.","3458941","Estradiol","Testicular Neoplasms",1,null,1]
["Estradiol","Testicular Neoplasms",0,1,"4479558",1974,"Testosterone and oestradiol in dogs with testicular tumours.","4479558","Estradiol","Testicular Neoplasms",1,null,1]
["Estradiol","Testicular Neoplasms",0,1,"6850507",1983,"Large-cell calcifying sertoli cell tumor of the testis. An ultrastructural, immunocytochemical, and biochemical study.","6850507","Estradiol","Testicular Neoplasms",1,null,1]
["Estradiol","Testis",0,1,"1017790",1976,"Oestradiol receptors in non-neoplastic gynaecomastic tissue of phenotypic males.","1017790","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1025346",1976,"Specific [3H]-estradiol binding in the fetal uterus and testis of guinea pig. Quantitative evolution of [3H]-estradiol receptors in the different fetal tissues (kidney, lung, uterus and testis) during fetal development.","1025346","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"10341717",1999,"Evidence of sex reversal in the gonads of chicken embryos after oestrogen treatment as detected by expression of lutropin receptor.","10341717","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"10385420",1999,"c-fos activity in Rana esculenta testis: seasonal and estradiol-induced changes.","10385420","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"10453915",1999,"Reproductive function in rats exposed neonatally to bisphenol A and estradiol benzoate.","10453915","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"10455051",1999,"Genetic variation in susceptibility to endocrine disruption by estrogen in mice.","10455051","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"10484726",1999,"Animal testing. One mouse's meat is another one's poison.","10484726","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"10525362",1999,"The effect of estrogen on the gonads and on in vitro conversion of androstenedione to testosterone, 11-ketotestosterone, and estradiol-17beta in Sparus aurata (Teleostei, Sparidae).","10525362","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"10527870",1999,"Estradiol-17beta stimulates the renewal of spermatogonial stem cells in males.","10527870","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"10867937",2000,"[The effect of prenatal stress on steroidogenesis in the gonads of Arctic foxes (Alopex lagopus)].","10867937","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"10868483",2000,"Sex steroids relative to alternative mating behaviors in the simultaneous hermaphrodite Serranus subligarius (Perciformes: Serranidae).","10868483","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"10911399",2000,"Induction of gonadal intersex in genotypic male rainbow trout (Oncorhynchus mykiss) embryos following immersion in estradiol-17beta.","10911399","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"10919273",2000,"Estrogenic induction of spermatogenesis in the hypogonadal mouse.","10919273","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"10926772",2000,"A molecular basis for estrogen-induced cryptorchidism.","10926772","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11014502",2000,"Effects of sex steroid hormones and their antagonists on mast cell number in the testis of the frog, Rana esculenta.","11014502","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11018755",2000,"Estradiol-induced mitogen-activated protein kinase (extracellular signal-regulated kinase 1 and 2) activity in the frog (Rana esculenta) testis.","11018755","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11133006",2000,"Effect of testosterone and 17beta-estradiol treatment on sex steroid binding proteins in the male of the green frog Rana esculenta.","11133006","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"113114",1979,"[Inhibitory action of estradiol on testosterone production in rat embryo].","113114","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11403898",2001,"Estradiol enhances the stimulatory effect of FSH on testicular maturation and contributes to precocious initiation of spermatogenesis.","11403898","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"11403906",2001,"beta-estradiol 3-benzoate affects spermatogenesis in the adult mouse.","11403906","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11466233",2001,"Estrogen-induced gonadal sex reversal in the tammar wallaby.","11466233","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11478683",2001,"Genetic variation in physiological sensitivity to estrogen in mice.","11478683","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1151930",1975,"Altered sexual development in male rats after oestrogen administration during the neonatal period.","1151930","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1154993",1975,"Effect of sex steroids on the male reproductive organs of the monitor lizard Varanus monitor (Linn.).","1154993","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1157758",1975,"Sexual differentiation of the mechanism controlling the preovulatory discharge of luteinizing hormone in sheep.","1157758","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11686542",2001,"Antifertility effects of estradiol in adult male rats.","11686542","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11733872",2001,"Novel male mice show gradual decline in the capacity to disrupt early pregnancy and in urinary excretion of testosterone and 17 beta-estradiol during the weeks immediately following castration.","11733872","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11800162",2001,"The influence of estrogen on the developing male marsupial.","11800162","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1180196",1975,"The effect of exogenous administration of oestrogens on the function of the epididymis and the accessory sex glands in the boar.","1180196","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11803558",2002,"17 beta-estradiol induces spermatogonial proliferation through mitogen-activated protein kinase (extracellular signal-regulated kinase 1/2) activity in the lizard (Podarcis s. sicula).","11803558","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"11842401",2002,"Morphological and hormonal parameters in two species of macaques: impact of seasonal breeding.","11842401","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1195247",1975,"17-Hydroxyandrogens and oestrogens in the plasma of normal and infertile men.","1195247","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"12090921",2002,"Effects of oestrogen treatment on testicular descent, inguinal closure and prostatic development in a male marsupial, Macropus eugenii.","12090921","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"12108785",2002,"Effect of compound CDRI 84/35 and synthetic estrogen on the seminiferous epithelium of immature rat.","12108785","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"12193375",2002,"Differential alteration of the reproductive axis by testosterone and estrogen in peripubertal and adult male Siberian hamsters (Phodopus sungorus).","12193375","Estradiol","Testis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2692,I2692)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2692,J2692)","v":"Testis"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2692,H2692)","v":"12211062"},2002,"Effects of the aromatase inhibitor fadrozole on plasma sex steroid secretion, spermatogenesis and epididymis morphology in the lizard, Podarcis sicula.","12211062","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1222901",1975,"The effect of 17 beta-estradiol acetate on the testis and thumb pad of Rana cyanophlyctis (Schn.) and Rana tigrina (Daud.).","1222901","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"12239125",2002,"Estrogen accelerates gonadal recrudescence in photo-regressed male siberian hamsters.","12239125","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"122442",1978,"Gynecomastia as a familial incomplete male pseudohermaphroditism type 1: a limited androgen resistance syndrome.","122442","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,0,"12265605",1978,"Hypogonadism in chronically lead-poisoned men.","12265605","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1237414",1975,"Pituitary and gonadal hormones in patients with varicocele.","1237414","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"12388134",2003,"Disruption of pubertal onset by exogenous testosterone and estrogen in two species of rodents.","12388134","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1239911",1975,"Effects of female sex hormones on histamine metabolism in guinea-pigs.","1239911","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"12524017",2003,"Effects of octylphenol and 17beta-estradiol on the gonads of guppies (Poecilia reticulata) exposed as adults via the water or as embryos via the mother.","12524017","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"12657744",2003,"Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture.","12657744","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"12722",1976,"[Effect of neonatal injections of estradiol, testosterone and cryproterone acetate on plasma and testicular testosterone and on the genital system in adult male mice].","12722","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"12814350",2003,"Inhibition of the basal and oestradiol-stimulated mitotic activity of primary spermatogonia by melatonin in the testis of the frog, Rana esculenta, in vivo and in vitro.","12814350","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"12840815",2003,"Degree of sex reversal as related to plasma steroid levels in genetic female chickens (Gallus domesticus) treated with Fadrozole.","12840815","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1291339",1992,"[Studies on the production rate of estradiol in the testis in male infertility--studies of the predictive values on therapeutic efficacy in patients with oligozoospermia].","1291339","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"12914527",2003,"Steroids control the aromatase gene expression in purified germ cells from the adult male rat.","12914527","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"12959643",2003,"The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy.","12959643","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1305122",1992,"Effect of estradiol treatment on male mice synaptonemal complexes: difference of sensitivity between neonates and adults.","1305122","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,0,"14121626",1964,"IN VITRO EXPOSURE OF RABBIT OVA TO ESTROGENS.","14121626","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,0,"14194452",1964,"CLINICAL, HORMONAL AND CYTOGENETIC FINDINGS IN A TRUE HERMAPHRODITE.","14194452","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,0,"14201828",1964,"[THE ENDOCRINE TESTICLE. (RECENT PHYSIOLOGICAL AND PHYSIOPATHOLOGICAL IDEAS)].","14201828","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,0,"14207040",1964,"RELATIONSHIP BETWEEN PROGESTATIONAL ACTIVITY AND CHEMICAL STRUCTURE OF SYNTHETIC STEROIDS.","14207040","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,0,"14208644",1964,"[BIOLOGIC STUDY OF A CASE OF \"FEMINIZING TESTIS\"].","14208644","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,0,"14209291",1964,"THE FEMINIZING SYNDROME IN MALE SUBJECTS WITH ADRENOCORTICAL NEOPLASMS.","14209291","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,0,"14245076",1965,"STEROID SYNTHESIS IN THE CRYPTORCHID TESTES OF THREE CASES OF THE \"TESTICULAR FEMINIZATION\" SYNDROME.","14245076","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,0,"14290160",1965,"STEROID BIOSYNTHESIS IN VITRO BY FEMINIZING TESTES.","14290160","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,0,"14301526",1965,"EFFECT OF ESTROGEN OR TESTOSTERONE ON INITIATION AND MAINTENANCE OF SPERMATOGENESIS IN THE RAT.","14301526","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"14555199",2003,"Male reproductive effects of octylphenol and estradiol in Fischer and Wistar rats.","14555199","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1459628",1992,"Differential response of testis and serum gonadotropins to testosterone in rats treated with a gonadotropin releasing hormone antagonist or estradiol 17 beta.","1459628","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"14613549",2003,"The antiestrogen ICI 182,780 decreases the expression of estrogen receptor-alpha but has no effect on estrogen receptor-beta and androgen receptor in rat efferent ductules.","14613549","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"14636640",2003,"Effects of steroid hormones on spermatogenesis and GnRH release in male Leopard frogs, Rana pipiens.","14636640","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"14648872",2004,"Toxicogenomic difference between diethylstilbestrol and 17beta-estradiol in mouse testicular gene expression by neonatal exposure.","14648872","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"14715828",2004,"Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: effects of testosterone, alendronate, and estradiol treatment.","14715828","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1479151",1992,"In vitro effect of hCG on steroidogenesis in the testicular tissue from a patient with complete androgen resistance.","1479151","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"15139905",2004,"Effects of the wood extractive betulinol and 17beta-oestradiol on reproduction in zebrafish, Danio rerio (Hamilton)--complications due to a bacterial infection.","15139905","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"15159111",2004,"Improvement in spermatogenic function after subcutaneous implantation of a capsule containing an aromatase inhibitor in four oligozoospermic dogs and one azoospermic dog with high plasma estradiol-17beta concentrations.","15159111","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"15205377",2004,"Effects of medroxyprogesterone and estradiol on the recovery of spermatogenesis in irradiated rats.","15205377","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"15350809",2004,"Dose- and photoperiod-dependent effects of 17beta-estradiol and the anti-estrogen ICI 182,780 on testicular structure, acceleration of spermatogenesis, and aromatase immunoexpression in immature bank voles.","15350809","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"15371802",2004,"Reproductive hormone levels in infants with cryptorchidism during postnatal activation of the pituitary-testicular axis.","15371802","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"15501383",2004,"Effects of neonatal administration of 17beta-estradiol, beta-estradiol 3-benzoate, or bisphenol A on mouse and rat spermatogenesis.","15501383","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"15642123",2005,"Alteration of the hypothalamic-pituitary-gonadal axis in estrogen- and androgen-treated adult male leopard frog, Rana pipiens.","15642123","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"15748716",2005,"Steroid-induced changes in the morphology of GnRH neurons in the male leopard frog, Rana pipiens: correlation with plasma gonadotropin and gonadal size.","15748716","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"15846054",2005,"Vitellogenin-immunohistochemistry in the liver and the testis of the medaka, Oryzias latipes, exposed to 17beta-estradiol and p-nonylphenol.","15846054","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"15848257",2005,"Plasma concentrations of estradiol and testosterone, gonadal aromatase activity and ultrastructure of the testis in Xenopus laevis exposed to estradiol or atrazine.","15848257","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"16078662",2005,"[Influence of estradiol benzoate on the testis development of rats].","16078662","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"16139364",2006,"All ZZ male Xenopus laevis provides a clear sex-reversal test for feminizing endocrine disruptors.","16139364","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"16162399",2006,"Reproductive abnormalities in adult male mice following preimplantation exposures to estradiol or pesticide methoxychlor.","16162399","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"16176578",2005,"Neonatal androgenization of hypogonadal (hpg) male mice does not abolish estradiol-induced FSH production and spermatogenesis.","16176578","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"16264094",2005,"Estrogenic induction of spermatogenesis in the hypogonadal (hpg) mouse: role of androgens.","16264094","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"16313069",2005,"Effect of estradiol on expression of cytoskeletal proteins during spermatogenesis in testis of sexually mature rats.","16313069","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"16541728",2005,"[Important functions of estrogens in men--breakthrough in contemporary medicine].","16541728","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1668899",1991,"Inhibition of fertility in the male mouse by combined androgen-antiandrogen therapy.","1668899","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"16723207",2006,"The effect of estrogen on testicular gonocyte maturation.","16723207","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"16756952",2006,"Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in the mouse testis.","16756952","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"16830234",2006,"Estradiol treatment induces testicular oxidative stress and germ cell apoptosis in rats.","16830234","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"17050857",2007,"17Beta-estradiol triggers postspawning in spermatogenically active gilthead seabream (Sparus aurata L.) males.","17050857","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"1719410",1991,"Testicular toxicity and mutagenicity of steroidal and non-steroidal estrogens in the male mouse.","1719410","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"17342729",2007,"Homologous regulation of estrogen receptor subtypes in goldfish (Carassius auratus).","17342729","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"17569695",2007,"Developmental changes in testicular sensitivity to estrogens throughout fetal and neonatal life.","17569695","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"18097524",2008,"Maturation, proliferation and apoptosis of seminal tubule cells at puberty after administration of estradiol, follicle stimulating hormone or both.","18097524","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"18217490",2007,"Effects of 17beta-estradiol on estrogen receptor alpha and beta mRNA expression in tissues of the olive flounder (Paralichthys olivaceus).","18217490","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"18230131",2008,"Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg) mouse.","18230131","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"18353327",2008,"Sex change of adult initial-phase male wrasse, Halichoeres trimaculatus by estradiol-17 beta treatment.","18353327","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"19007549",2008,"Oestradiol-induced spermatogenesis requires a functional androgen receptor.","19007549","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"19095743",2009,"Disruption of tubulobulbar complex by high intratesticular estrogens leading to failed spermiation.","19095743","Estradiol","Testis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2756,I2756)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2756,J2756)","v":"Testis"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2756,H2756)","v":"19136390"},2009,"Estrogen enhances recovery from radiation-induced spermatogonial arrest in rat testes.","19136390","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"19233",1977,"Estradiol binding capacity in the cryptorchid rat testis.","19233","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"19292035",2009,"[Effects of prepubertal exposure to estradiol benzoate on testicular development and function of Sprague-Dawley rats].","19292035","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"19420009",2009,"Oestrogen-induced androgen insufficiency results in a reduction of proliferation and differentiation of spermatogonia in the zebrafish testis.","19420009","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"1950593",1991,"Effect of estradiol on spermatogenesis and testicular hydroxysteroid dehydrogenase activities in Bidder's organectomized toad (Bufo melanostictus).","1950593","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"19799515",2009,"Estradiol-17beta treatment induces intersexual gonadal development in the pufferfish, Takifugu rubripes.","19799515","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"19903717",2010,"Induction of spermatogenic cell apoptosis in prepubertal rat testes irrespective of testicular steroidogenesis: a possible estrogenic effect of di(n-butyl) phthalate.","19903717","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"19947557",2009,"[Effects of exposure to estradiol valerate in early pregnancy on the reproductive system development of F1 male rats].","19947557","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"20089883",2010,"Interdependence of platelet-derived growth factor and estrogen-signaling pathways in inducing neonatal rat testicular gonocytes proliferation.","20089883","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"20385159",2010,"Post-hatch oral estrogen in zebra finches (Taeniopygia guttata): is infertility due to disrupted testes morphology or reduced copulatory behavior?","20385159","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"20410197",2010,"Estradiol induction of spermatogenesis is mediated via an estrogen receptor-{alpha} mechanism involving neuroendocrine activation of follicle-stimulating hormone secretion.","20410197","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"20601066",2010,"Upregulation of estrogen receptor subtypes and vitellogenin mRNA in cinnamon clownfish Amphiprion melanopus during the sex change process: profiles on effects of 17beta-estradiol.","20601066","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"20820944",2011,"Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17?-estradiol level in induction of acute oxidative stress.","20820944","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"20821545",2010,"Effects of 17 beta-estradiol exposure on Xenopus laevis gonadal histopathology.","20821545","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"20883121",2010,"AR versus ER (?) expression in the testis and pituitary following chronic estrogen administration in adult rat.","20883121","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"21117145",2011,"Role of estrogen in spermatogenesis in initial phase males of the three-spot wrasse (Halichoeres trimaculatus): effect of aromatase inhibitor on the testis.","21117145","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"2117584",1990,"Prolonged suppression of spermatogenesis by oestrogen does not preserve the seminiferous epithelium in procarbazine-treated rats.","2117584","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"21333471",2011,"Early prepubertal testis criteria, seminiferous epithelium and hormone concentrations as related to testicular development in beef bulls.","21333471","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"21653891",2011,"Estrogen-regulated genes in rat testes and their relationship to recovery of spermatogenesis after irradiation.","21653891","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"21712082",2011,"Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on steroid concentrations in blood and gonads of chicken embryo.","21712082","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"21849707",2011,"Defining the impact of estrogen on spermatogonial fate.","21849707","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"22245262",2012,"Ambiguities in the relationship between gonadal steroids and reproduction in axolotls (Ambystoma mexicanum).","22245262","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"22752971",2012,"Effects of transplacental 17-?-ethynyl estradiol or bisphenol A on the developmental profile of steroidogenic acute regulatory protein in the rat testis.","22752971","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"22898016",2012,"Testicular testosterone: estradiol ratio in domestic cats and its relationship to spermatogenesis and epididymal sperm morphology.","22898016","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"22999797",2013,"Clomiphene citrate potentiates the adverse effects of estrogen on rat testis and down-regulates the expression of steroidogenic enzyme genes.","22999797","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"23041508",2012,"Novel molecular targets associated with testicular dysgenesis induced by gestational exposure to diethylhexyl phthalate in the rat: a role for estradiol.","23041508","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"23283575",2013,"Cyp17a1 and Cyp19a1 in the zebrafish testis are differentially affected by oestradiol.","23283575","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"23319664",2013,"In vivo exposure to 17?-estradiol triggers premature sperm capacitation in cauda epididymis.","23319664","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"23665278",2013,"Effects of steroid hormones on reproduction- and detoxification-related gene expression in adult male mosquitofish, Gambusia affinis.","23665278","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"23677985",2013,"Low 17beta-estradiol levels in CNR1 knock-out mice affect spermatid chromatin remodeling by interfering with chromatin reorganization.","23677985","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"24011196",2013,"Estradiol and testosterone inhibit rat seminiferous tubule development in a hormone-specific way.","24011196","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"242175",1975,"The effect of artificial cryptorchidism on serum oestrogen and testosterone levels in the adult male rat.","242175","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"24499511",2014,"Alterations in the estrogen environment of the testis contribute to declining sperm production in aging rats.","24499511","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"24709360",2014,"Vitellogenin of Fujian oyster, Crassostrea angulata: Synthesized in the ovary and controlled by estradiol-17?.","24709360","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"2569957",1989,"Concentrations of oestradiol and testosterone in peripheral and spermatic venous blood of dogs with unilateral cryptorchidism.","2569957","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"2857482",1985,"Kinetics of the steroidogenic response to single versus repeated doses of human chorionic gonadotropin in boys in prepuberty and early puberty.","2857482","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"2858322",1985,"The influence of exogenous estradiol on bobwhite quail (Colinus virginianus) reproductive systems.","2858322","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"309840",1978,"A histochemical study of the adrenogenital syndrome in frog tadpoles.","309840","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"311733",1978,"Maturation of 17 beta-estradiol binding protein in the hypothalamus and anterior pituitary of male rats.","311733","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"3134781",1987,"Demonstration of direct effect of estrogen on rat spermatogenesis.","3134781","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"3351446",1988,"Evidence for the sexual bipotentiality of spermatogonia in the fish, Oryzias latipes.","3351446","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"3360185",1988,"Concentrations of estradiol in serum and testis tissue in patients with fertility disorders.","3360185","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"3375504",1988,"Estimation of human reproductive risk from animal studies: determination of interspecies extrapolation factors for steroid hormone effects on the male.","3375504","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"36274",1979,"Alterations in steroidogenesis and human chorionic gonadotropin binding in the cryptorchid rat testis.","36274","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"3671531",1987,"Prenatal stress reduces estradiol-induced prolactin release in male and female rats.","3671531","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"395188",1979,"Recent advances in studies on estrogen biosynthesis.","395188","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4035118",1985,"[Testicular response to human chorionic gonadotropin in infertile patients according to the testicular histologic pattern].","4035118","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4059406",1985,"Hyperprolactinemia and male sexual behavior: effects of steroid replacement with estrogen plus dihydrotestosterone.","4059406","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"40899",1978,"Possible effects of ovocyclin in male reproduction.","40899","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4110091",1971,"Studies on the endocrine properties of a new progestational steroid 4,6-dichloro-16-methylene-17-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate (MDAP).","4110091","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4150097",1970,"The effects of steroid and gonadotrophic hormones in vitro on the metabolic activity of normal and cryptorchid rat testicular tissues.","4150097","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4151680",1974,"Plasma testosterone and estradiol concentration in prepubertal boys with cryptorchidism before and after dexamethasone and after human chorionic gonadotropin administration.","4151680","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"4152351",1973,"[Growth and structure of cryptorchid testes in mice born of mothers treated by oestradiol during pregnancy (author's transl)].","4152351","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4153231",1974,"[Plasma levels of testosterone and estradiol in prepuberal children with cryptorchism and anorchia before and after administration of HCG].","4153231","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4153922",1974,"[Endocrine function of the testis in 125 cases of cryptorchism].","4153922","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4239445",1969,"Levels of testosterone, androstenedione, estrone and estradiol-17 beta in the testes of fetal sheep.","4239445","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4259253",1972,"Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.","4259253","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4295115",1968,"Effect of metyrapone on the excretion of oestrogen in man.","4295115","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4359981",1971,"Effect of oestradiol-3,17beta dipropionate on spermatogenesis and lysosomal enzymes in the rat testis.","4359981","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4363158",1974,"Long-term therapy with low-dose cisclomiphene in male infertility: effects on semen, serum FSH, LH, testosterone ond estradiol, and carbohydrate tolerance.","4363158","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4368492",1974,"Chemical determination of oestrogen distribution in the foetus and placenta of the domestic pig.","4368492","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4400631",1972,"The hormonal response to HCG stimulation in male children and adolescents.","4400631","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4405594",1972,"[Comparative study of changes in gonadotropic cells and testis in male rats treated with estrogens during the neonatal period].","4405594","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"4426307",1974,"Ultrastructural changes in the testis of mice given neonatal injections of estrogen.","4426307","Estradiol","Testis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2820,I2820)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2820,J2820)","v":"Testis"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2820,H2820)","v":"4430442"},1974,"Effects of testosterone and oestradiol on gonadectomized and intact male and female river lampreys (Lampetra fluviatilis (L.) Gray).","4430442","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4463806",1974,"[Proceedings: Sexual behavior and genital tract of adult male rats previously treated by estrogens in the early neonatal stage (author's transl)].","4463806","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4479707",1974,"Gonadal factors regulating the activity of the 17beta-hydroxysteroid oxidoreductase in rat liver.","4479707","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4536880",1972,"Neonatal sterilization of rodents with steroid hormones. 4. The influence of estradiol benzoate injected into five day old male rats on the weight of testes and ventral prostate and histology of the seminiferous epithelium and the pituitary gland during sexual maturation.","4536880","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4609754",1974,"Neural control of the estrogen-dependent twenty-four-hour periodicity of LH release in the golden hamster.","4609754","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4663037",1972,"[Appearance of disorders in cryptorchid testis of mice after estradiol injection of the pregnant mother].","4663037","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4663532",1972,"Effect of sex hormones on development of urogenital system in reptile embryos.","4663532","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4673129",1972,"Hormones and the ontogenesis of pituitary regulating mechanisms.","4673129","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4675694",1972,"[The effect of ethymizole on the gonadotropic function of the hypophysis].","4675694","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4678850",1972,"Inhibitory effect of androgen on induction of permanent changes in the testis by neonatal injections of estrogen in mice.","4678850","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4678851",1972,"Effects of gonadotropins on the occurrence of permanent changes in the testis of mice given neonatal estrogen injections.","4678851","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4716418",1973,"The normal development of the blood-testis barrier and the effects of clomiphene and estrogen treatment.","4716418","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4724755",1973,"Testes of roosters treated with a single dose of estradiol dipropionate.","4724755","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4742008",1973,"Fertilizing ability of hamster spermatozoa following subcutaneous implantation or insertion into seminal vesicles of silastic tubes containing estradiol benzoate.","4742008","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4778697",1973,"[The effect of unilateral castration on the testes of mature rats receiving repeated injections of estradiol-propionate].","4778697","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4784710",1973,"Differentiation of steroid metabolism in the rat and mechanisms of neonatal androgen action.","4784710","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4785735",1973,"Estrogen-activated sexual behavior in male rats.","4785735","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4795966",1973,"Plasma estrogens in childhood and puberty under physiologic and pathologic conditions.","4795966","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4799006",1973,"[Induction of estrogen production in the embryonic chicken testicle by dihydrotestosterone].","4799006","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4799008",1973,"[Gonadal function of rats following prenatal injection of estradiol benzoate].","4799008","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4812464",1974,"Effects of testosterone and follicle-stimulating hormone on spermatogenesis in adult mice during treatment with oestradiol.","4812464","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4853109",1974,"Mating in castrated male rats during combined treatment with estradiol benzoate and fluoxymesterone.","4853109","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4856161",1974,"Neonatal bonadal hormones: effect on maternal and sexual behavior in the male rat.","4856161","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"486667",1979,"Interactions of testosterone and estradiol-17 beta on the reproductive tract of the male rat.","486667","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4868640",1968,"The immunologic problem of pregnancy. V. The effect of estrogen and progesterone on allograft survival.","4868640","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"487999",1979,"Studies on the regulation of the onset of steroid hormone biosynthesis in fetal rabbit gonads.","487999","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"4963604",1967,"[Secretion of estrone and estradiol by the feminized chick-embryo testis].","4963604","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"5067082",1972,"[Sex and age dependent development of activation patterns of steroid hormone metabolism enzymes in rat liver after neonatal interference with sex differentiation].","5067082","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"5091295",1971,"Comparison of the effects of cyproterone, cyproterone acetate and oestradiol on testicular function, accessory sexual glands and fertility in a long-term study on rats.","5091295","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"5108101",1971,"Biosynthesis of testosterone and oestrogens in vitro by the testicular tissue from patients with Klinefelter's syndrome.","5108101","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"5167836",1971,"The effects of gonadal hormones on the aggressive behaviour of adult golden hamsters (Mesocricetus auratus).","5167836","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"5463882",1970,"Effect of neonatally administered estrogen on development of male and female rats.","5463882","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"5537134",1970,"Testicular damages in neonatally estrogenized adult mice.","5537134","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"568390",1978,"Production and origin of estrogen in two true hermaphrodites.","568390","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"5718720",1968,"Effect of hormones on gonads of sterile hybrid ducks.","5718720","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"57575",1976,"Protection of spermatogenesis by alpha2u globulin in rats treated with oestrogen.","57575","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"5793461",1969,"Testicular development in rats treated with several steroids shortly after birth.","5793461","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"5847114",1965,"[Developmental abnormalities of the testicle of her offspring after estrogen injection into the pregnant mother].","5847114","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"5891512",1965,"[Changes of seminal epithelium following repeated doses of estradiol. Investigations on the rat testis].","5891512","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"5948902",1966,"Development of a vagina in male rats by inhibiting androgen receptors with an anti-androgen during the critical phase of organogenesis.","5948902","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6050510",1967,"Effect of estradiol-17-beta on the distribution of 3-beta-hydroxysteroid dehydrogenase in the testes of Rana esculenta and Lacerta sicula.","6050510","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6069257",1967,"Suppression of oestrus behaviour in the immature male rat.","6069257","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6105952",1980,"Cryptorchid rhesus macaques: long term studies on changes in gonadotropins and gonadal steroids.","6105952","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6105953",1980,"Influence of bilateral cryptorchidism in the mature rat: alterations in testicular function and serum hormone levels.","6105953","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6108036",1980,"Decreased testicular response to acute LH-stimulation and increased intratesticular concentration of oestradiol-17 beta in the abdominal testes in cryptorchid rats.","6108036","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6115686",1981,"Cryptorchidism: residual effects on steroid-regulated gonadotropin release in recently castrated rhesus monkeys.","6115686","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6118000",1980,"[Regulation of testicular function by estradiol. I. Standard of development and variations in the post-cryptorchism estradiol receptor].","6118000","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6186760",1983,"Effect of alpha 2u-globulin on serum concentration of gonadotrophins and testicular activity in oestrogen-treated rats.","6186760","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6318929",1983,"[Secretion in vitro of 17 beta estradiol by the gonads of female rat fetuses in the presence of various precursors and of dibutyryl cAMP].","6318929","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6405991",1983,"[Aromatization of testosterone by the rat embryo testis].","6405991","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6421963",1984,"Danazol suppression of gonadal estradiol-17 beta secretion--report of two sibling cases with a complete form of testicular feminization on gonadal ultrastructure and endocrine status.","6421963","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6431658",1984,"Endocrine profile and seminal plasma composition in Hansen's disease.","6431658","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6482429",1984,"Testosterone, dihydrotestosterone and estradiol-17 beta levels in maternal and fetal plasma and in fetal testes in the rat.","6482429","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6618997",1983,"The effect of estrogen administration in vivo on the elemental composition of the intraluminal fluids of the seminiferous tubules, rete testis, and epididymis of the rat.","6618997","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6772248",1980,"Effects of intranasal administration of hormonal steroids on serum testosterone and spermatogenesis in rhesus monkey (Macaca mulatta).","6772248","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"680194",1978,"Preliminary studies on streoid-binding proteins in human testes of testicular feminization syndrome.","680194","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6833460",1983,"Human chorionic gonadotropin and testicular function: stimulation of testosterone, testosterone precursors, and sperm production despite high estradiol levels.","6833460","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"694966",1978,"The effect of the administration of spironolactone on the concentration of plasma testosterone, estradiol and cortisol in male dogs (1).","694966","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"6991014",1980,"Sexual differentiation: early hormone synthesis and action.","6991014","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"7045269",1982,"Initiation of spermatogenesis and testicular growth in oestradiol-17 beta-implanted bull calves with pulsatile infusion of luteinizing hormone releasing hormone.","7045269","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"7095416",1982,"Action of estradiol on the hermaphroditism induced by testicular graft in the female chick embryo.","7095416","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"7122318",1982,"Effects of cyproterone acetate and oestradiol benzoate on the rat testis. Morphometric study after treatment over 35 days.","7122318","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"719098",1978,"Recovery of testicular and pituitary functions in adult male rats after cessation of short and long term estradiol treatment.","719098","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"7339133",1981,"[Studies on testicular endocrinological function by estimation of plasma testosterone, estradiol and estradiol testosterone ratio. Studies on testicular function; report 9 (author's transl)].","7339133","Estradiol","Testis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2884,I2884)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2884,J2884)","v":"Testis"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2884,H2884)","v":"7422674"},1980,"Long-term effects of neonatal administration of estrogen and progesterone, alone or in combination, on male BALB/c and BALB/cfC3H mice.","7422674","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"7431312",1980,"Gonadotrophin-induced reinitiation of meiosis in testes of oestradiol-treated prepubertal rats.","7431312","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"7441832",1980,"Testicular function in Klinefelter's syndrome.","7441832","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"746885",1978,"[Testicular action of estrogens and antiandrogens--karyo-, histometric and histochemical studies of dog testis].","746885","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"7645764",1995,"Action of testosterone on the estradiol-induced feminization of the male chick embryo.","7645764","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"7702871",1995,"Effect of estradiol and progesterone on c-myc expression in the sea star testis and the seasonal regulation of spermatogenesis.","7702871","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"7821772",1994,"Effects of lamprey gonadotropin-releasing hormone-III on steroidogenesis and spermiation in male sea lampreys.","7821772","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"7929722",1994,"Serum luteinizing hormone pulsatility and intratesticular testosterone and oestradiol concentrations in idiopathic infertile men with high and normal follicle stimulating hormone serum concentrations.","7929722","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"801317",1976,"[The histological modifications of genital system of oestradiol benzoate treated male rats (author's transl)].","801317","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"801619",1976,"[Gonadal function in the rat after the pre- or postnatal administration of a combination of androgens and estrogens].","801619","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"8070709",1994,"[Comparison between the influence of estradiol benzoate, testosterone propionate and human chorionic gonadotropin on initiation of spermatogenesis in the rat].","8070709","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"8070710",1994,"[Tamoxifen and spermatogenesis in rats subjected to effects of estradiol].","8070710","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"832808",1977,"Seasonal changes in plasma cortisol, testosterone and oestradiol-17beta-in the plaice, Pleuronectes platessa L.","832808","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"864656",1977,"Spermatogenesis in hybrid mice treated with oestrogen and testosterone.","864656","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"8756553",1996,"Relationship among hormonal treatments, suppression of spermatogenesis, and testicular protection from chemotherapy-induced damage.","8756553","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"8760854",1996,"Further observations on the early events that contribute to establishing the morphological pattern shown by the oestradiol suppressed testis.","8760854","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"8804560",1996,"Gonadal transformation in male Rana catesbeiana tadpoles intraperitoneally implanted with estradiol capsules.","8804560","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"8856445",1996,"Comparison of circulating concentrations of reproductive hormones in boars of lines selected for size of testes or number of ovulations and embryonal survival to concentrations in respective control lines.","8856445","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"8930608",1996,"Effect of 17 beta-estradiol, testosterone, and 11-ketotestosterone on 17,20 beta-dihydroxy-4-pregnen-3-one production in the rainbow trout testis.","8930608","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"8940662",1996,"Induction of apoptotic cell death in the seminiferous tubule of the adult rat testis: assessment of the germ cell types that exhibit the ability to enter apoptosis after hormone suppression by oestradiol treatment.","8940662","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"8941",1976,"Hypophyso-gonadal function in the cryptorchid child: differences between unilateral and bilateral cryptorchids.","8941","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"8966101",1996,"[Precocious maturation of the testis associated with excessive secretion of estradiol and testosterone by Leydig cells].","8966101","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"9143141",1997,"17 beta-estradiol effects on mast cell number and spermatogonial mitotic index in the testis of the frog, Rana esculenta.","9143141","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"9268618",1997,"Correlation among thermosensitive period, estradiol response, and gonad differentiation in the sea turtle Lepidochelys olivacea.","9268618","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"9440251",1997,"Perinatal estrogen exposure: later repercussion on the fertility of rats.","9440251","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"952594",1976,"[Evaluation of gonadotropic and gonadal secretions in primary abnormalities of the gonads and male pseudohermaphrodism before and after the age of puberty].","952594","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"9649919",1998,"Tamoxifen-induced light and electron microscopic changes in the rat testicular morphology and serum hormonal profile of reproductive hormones.","9649919","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"9742652",1998,"90-day feeding and one-generation reproduction study in Crl:CD BR rats with 17 beta-estradiol.","9742652","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"9742654",1998,"Effects of dietary 17 beta-estradiol exposure on serum hormone concentrations and testicular parameters in male Crl:CD BR rats.","9742654","Estradiol","Testis",1,null,1]
["Estradiol","Testis",1,1,"9742655",1998,"Sensitivity of a Tier I screening battery compared to an in utero exposure for detecting the estrogen receptor agonist 17 beta-estradiol.","9742655","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"9768658",1998,"A reliable endocrine test with human menopausal gonadotropins for diagnosis of true hermaphroditism in early infancy.","9768658","Estradiol","Testis",1,null,1]
["Estradiol","Testis",0,1,"992971",1976,"Hormonal control of seminiferous tubule contractions. A hypothesis of sperm transport from the testicle.","992971","Estradiol","Testis",1,null,1]
["Estradiol","Turner Syndrome",0,0,"10781652",2000,"Lp(a) and lipids in adult Turner's syndrome: impact of treatment with 17beta-estradiol and norethisterone.","10781652","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",1,0,"11140397",2000,"Contact dermatitis from estradiol in a transdermal therapeutic system.","11140397","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"11357006",2000,"Low areal bone mineral density values in adolescents and young adult turner syndrome patients increase after long-term transdermal estradiol therapy.","11357006","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"11430712",2001,"Morning versus evening administration of estradiol to girls with turner syndrome receiving growth hormone: impact on growth hormone and metabolism. A randomized placebo-controlled crossover study.","11430712","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"11531930",2001,"Hormone replacement therapy may improve hepatic function in women with Turner's syndrome.","11531930","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"1164958",1975,"[Levels of estrone, estradiol 17 beta and testosterone in girls during normal puberty. Applications in pathology].","1164958","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"11786684",2001,"Turner's syndrome: a paediatric perspective.","11786684","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"12585345",2003,"Estradiol levels in girls with Turner's syndrome compared to normal prepubertal girls as determined by an ultrasensitive assay.","12585345","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",1,0,"12629094",2003,"Final height in girls with turner syndrome after long-term growth hormone treatment in three dosages and low dose estrogens.","12629094","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"14201986",1963,"[GONADAL DYSGENESIS WITH FEMALE PHENOTYPE (TURNER'S SYNDROME)].","14201986","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"14444069",1960,"[The effect of estradiol on the free plasma 17-hydroxycorticosteroids in the menopause and in Turner's syndrome].","14444069","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",1,0,"15240598",2004,"Use of percutaneous estrogen gel for induction of puberty in girls with Turner syndrome.","15240598","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"1555688",1992,"An analysis of the variation of plasma concentrations of placental protein 14 in artificial cycles.","1555688","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"15853835",2005,"Effect of growth hormone and 17beta-oestradiol treatment on metabolism and body composition in girls with Turner syndrome.","15853835","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"16189255",2005,"Salutary effects of combining early very low-dose systemic estradiol with growth hormone therapy in girls with Turner syndrome.","16189255","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"1632017",1992,"[Treatment of girls with Turner's syndrome with growth hormone and estrogen--1-year experiences].","1632017","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"16641858",2006,"Growth and long-term hormonal therapy.","16641858","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"16735134",2006,"Appropriate use of estrogen replacement therapy in adolescents and young adults with Turner syndrome and hypopituitarism in light of the Women's Health Initiative.","16735134","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"16735135",2006,"Evidence for early initiation of growth hormone and transdermal estradiol therapies in girls with Turner syndrome.","16735135","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"17371475",2007,"A dose-response study of hormone replacement in young hypogonadal women: effects on intima media thickness and metabolism.","17371475","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"17535868",2007,"Quantitative liver functions in Turner syndrome with and without hormone replacement therapy.","17535868","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"180042",1976,"Testosterone-estradiol-binding globulin in patients with Turner's syndrome: effects of estrogens and acute growth hormone administration.","180042","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"1883788",1991,"The variation of endometrial response to a standard hormone replacement therapy in women with premature ovarian failure. An ultrasonographic and histological study.","1883788","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"20956269",2010,"FSH, LH, inhibin B and estradiol levels in Turner syndrome depend on age and karyotype: longitudinal study of 70 Turner girls with or without spontaneous puberty.","20956269","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"2126236",1990,"A physiological mode of puberty induction in hypogonadal girls by low dose transdermal 17 beta-oestradiol.","2126236","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",1,0,"21378088",2011,"Metabolic and cardiovascular outcomes in a group of adult patients with Turner's syndrome under hormonal replacement therapy.","21378088","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"21880799",2011,"Pharmacokinetics and pharmacodynamics of oral and transdermal 17? estradiol in girls with Turner syndrome.","21880799","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",1,0,"22807477",2012,"Individualised vs fixed dose of oral 17?-oestradiol for induction of puberty in girls with Turner syndrome: an open-randomised parallel trial.","22807477","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"22946283",2012,"Estrogen therapy in Turner syndrome: does the type, dose and mode of delivery matter?","22946283","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"23678038",2013,"Metabolic effects of oral versus transdermal 17?-estradiol (E?): a randomized clinical trial in girls with Turner syndrome.","23678038","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"2516784",1989,"Melatonin secretion in Turner's syndrome: lack of effect of oestrogen administration.","2516784","Estradiol","Turner Syndrome",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I2948,I2948)","v":"Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J2948,J2948)","v":"Turner Syndrome"},0,0,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H2948,H2948)","v":"3095120"},1986,"New aspects of oestrogen/gestagen-induced growth and endocrine changes in individuals with Turner syndrome.","3095120","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"3195333",1988,"Oestrogen therapy in Turner's syndrome.","3195333","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"3465157",1986,"Growth and development in girls with Turner's syndrome during early therapy with low doses of estradiol.","3465157","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,1,"361318",1978,"Sex steroid hormones and antibodies to Candida albicans.","361318","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"4370903",1974,"The effects of prolonged physiologic estradiol therapy on the maturation of hypogonadal teen-agers.","4370903","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"4742538",1973,"The effects of low doses of depot estradiol and testosterone in teenagers with ovarian failure and Turner's syndrome.","4742538","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,1,"4795966",1973,"Plasma estrogens in childhood and puberty under physiologic and pathologic conditions.","4795966","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"4844524",1974,"The absence of positive feedback between estrogen and luteinizing hormone in sexually immature girls.","4844524","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,1,"5078369",1972,"[Plasma estrogen concentration in children].","5078369","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"5901834",1966,"Steroid synthesis in vitro by tumour tissue from a dysgenetic gonad.","5901834","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,1,"606452",1977,"Sex steroid hormones and circulating IgE levels.","606452","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",1,0,"6738374",1984,"Endometrial changes after long-term use of continuous oestrogen and cyclic progestogen.","6738374","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"6741400",1984,"Influence of oestrogen in high and low doses on plasma steroid concentrations in girls with tall stature and Turner syndrome.","6741400","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"724356",1978,"Treatment of Turner's syndrome with estrogen.","724356","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"7584704",1995,"Comparison of transdermal and oral estrogen therapy in girls with Turner's syndrome.","7584704","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"7589660",1995,"Exaggerated effects of progestogen on uterine artery pulsatility index in Turner's syndrome patients receiving hormone replacement therapy.","7589660","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"809301",1975,"Feedback modulation of hypothalamic-pituitary unit by estrogen in the secretion of gonadotropins and prolactin in humans.","809301","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",1,0,"8157028",1994,"Growth hormone and 17 beta-oestradiol treatment of Turner girls--2-year results.","8157028","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"8395456",1993,"Results of two years of growth hormone treatment followed by combined growth hormone and oestradiol in Turner syndrome. The Norwegian Turner Study Group.","8395456","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,1,"8498151",1993,"Opposite effects of growth hormone and estrogens on the pregnancy zone protein serum levels in children and adolescents.","8498151","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"8761153",1996,"[Turner syndrome and digestive telangiectasis: an additional value of estrogen-progestational treatment].","8761153","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"8822425",1995,"A reappraisal of the feedback effects of oestradiol upon luteinizing hormone surge.","8822425","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"909658",1977,"Clinical and endocrine studies in menopausal women after estradiol pellet implantation.","909658","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,0,"9253336",1997,"Body composition and physical fitness are major determinants of the growth hormone-insulin-like growth factor axis aberrations in adult Turner's syndrome, with important modulations by treatment with 17 beta-estradiol.","9253336","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Turner Syndrome",0,1,"952594",1976,"[Evaluation of gonadotropic and gonadal secretions in primary abnormalities of the gonads and male pseudohermaphrodism before and after the age of puberty].","952594","Estradiol","Turner Syndrome",1,null,1]
["Estradiol","Urethra",0,0,"20472273",2010,"Effects of birth trauma and estrogen on urethral elastic fibers and elastin expression.","20472273","Estradiol","Urethra",1,null,1]
["Estradiol","Urethra",0,1,"567627",1978,"Effect of estrogen on sensitivity of rabbit bladder and urethra to phenylephrine.","567627","Estradiol","Urethra",1,null,1]
["Estradiol","Urethra",0,1,"5753098",1968,"[Genital malformations in adult mice resulting from prenatal estrogenic action. II. The female].","5753098","Estradiol","Urethra",1,null,1]
["Estradiol","Urogenital Abnormalities",1,0,"4975498",1969,"[On an anomaly of genital canals observed in Greek tortoise (Testudo graeca L.) embryos treated by estradiol benzoate].","4975498","Estradiol","Urogenital Abnormalities",1,null,1]
["Estradiol","Vas Deferens",0,1,"1154993",1975,"Effect of sex steroids on the male reproductive organs of the monitor lizard Varanus monitor (Linn.).","1154993","Estradiol","Vas Deferens",1,null,1]
["Estradiol","Vas Deferens",0,1,"4597757",1974,"The inhibition of fertilizing ability of epididymal spermatozoa by the administration of oestradiol benzoate to testosterone-maintained hypophysectomized or castrated hamsters.","4597757","Estradiol","Vas Deferens",1,null,1]
["Ethinyl Estradiol","Adrenal Hyperplasia, Congenital",0,0,"15031776",2004,"Urinary 6-sulfatoxymelatonin excretion in hyperandrogenic women: the effect of cyproterone acetate-ethinyl estradiol treatment.","15031776","Ethinyl Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Ethinyl Estradiol","Adrenal Hyperplasia, Congenital",0,0,"4174078",1967,"[Differential diagnosis and treatment of hirsutism].","4174078","Ethinyl Estradiol","Adrenal Hyperplasia, Congenital",1,null,1]
["Ethinyl Estradiol","Adrenogenital Syndrome",0,0,"14105459",1964,"URINARY CORTISOL EXCRETION AS A TEST OF ADRENAL CORTICAL FUNCTION.","14105459","Ethinyl Estradiol","Adrenogenital Syndrome",1,null,1]
["Ethinyl Estradiol","Adrenogenital Syndrome",0,0,"14309124",1964,"[DRUG THERAPY OF HIRSUTISM].","14309124","Ethinyl Estradiol","Adrenogenital Syndrome",1,null,1]
["Ethinyl Estradiol","Androgen-Insensitivity Syndrome",1,1,"10492898",1999,"The avian egg as a test system for endocrine disrupters: effects of diethylstilbestrol and ethynylestradiol on sex organ development.","10492898","Ethinyl Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Ethinyl Estradiol","Androgen-Insensitivity Syndrome",0,1,"4206854",1974,"[Effects of ethynil estradiol and of androgens on the parameters of thyroid function in the syndrome of male pseudohermaphroditism with testicular feminization].","4206854","Ethinyl Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Ethinyl Estradiol","Androgen-Insensitivity Syndrome",0,1,"4621809",1972,"The concentration and binding of thyroxine in the serum of patients with the testicular feminization syndrome: observations on the effects of ethinyl estradiol and norethandrolone.","4621809","Ethinyl Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Ethinyl Estradiol","Androgen-Insensitivity Syndrome",0,1,"589801",1977,"Failure of positive feedback in normal men and subjects with testicular feminization.","589801","Ethinyl Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Ethinyl Estradiol","Androgen-Insensitivity Syndrome",0,1,"6230548",1984,"Effect of estrogens on luteinizing hormone release in testicular feminization syndrome before and after gonadectomy.","6230548","Ethinyl Estradiol","Androgen-Insensitivity Syndrome",1,null,1]
["Ethinyl Estradiol","Cryptorchidism",0,0,"14130828",1964,"THE HORMONES AND PUBERTY.","14130828","Ethinyl Estradiol","Cryptorchidism",1,null,1]
["Ethinyl Estradiol","Cryptorchidism",1,1,"1977467",1990,"The effect of in utero ethinyl oestradiol exposure on the risk of cryptorchid testis and testicular teratoma in mice.","1977467","Ethinyl Estradiol","Cryptorchidism",1,null,1]
["Ethinyl Estradiol","Cryptorchidism",1,1,"2874623",1986,"Leydig cell hyperplasia in fetal mice treated transplacentally with ethinyl estradiol.","2874623","Ethinyl Estradiol","Cryptorchidism",1,null,1]
["Ethinyl Estradiol","Cryptorchidism",1,1,"2876659",1986,"Accelerated differentiation in seminiferous tubules of fetal mice prenatally exposed to ethinyl estradiol.","2876659","Ethinyl Estradiol","Cryptorchidism",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,1,"12550100",2003,"Effects of 17 alpha-ethinylestradiol on sexual development of the amphipod Hyalella azteca.","12550100","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,1,"12758006",2003,"Developmental estrogenic exposure in zebrafish (Danio rerio): I. Effects on sex ratio and breeding success.","12758006","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,1,"12758007",2003,"Developmental estrogenic exposure in zebrafish (Danio rerio): II. Histological evaluation of gametogenesis and organ toxicity.","12758007","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",0,0,"14063709",1963,"FETAL EFFECTS OF STEROID THERAPY DURING PREGNANCY.","14063709","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",0,1,"14568354",2003,"Gonad development and vitellogenin production in zebrafish (Danio rerio) exposed to ethinylestradiol and methyltestosterone.","14568354","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,1,"18206232",2008,"Comparison of ethinylestradiol and nonylphenol effects on reproduction of Chinese rare minnows (Gobiocypris rarus).","18206232","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,1,"18453011",2008,"Effects of 4-nonylphenol and 17alpha-ethynylestradiol exposure in the Sydney rock oyster, Saccostrea glomerata: Vitellogenin induction and gonadal development.","18453011","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,1,"19184736",2009,"Xenopus tropicalis as a test system for developmental and reproductive toxicity.","19184736","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,1,"20700763",2010,"Exposure to 17?-ethynylestradiol causes dose and temporally dependent changes in intersex, females and vitellogenin production in the Sydney rock oyster.","20700763","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,1,"22619116",2012,"Development of a molecular biomarker for detecting intersex after exposure of male medaka fish to synthetic estrogen.","22619116","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,0,"22622553",2012,"Environmental science: The hidden costs of flexible fertility.","22622553","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,1,"22692001",2012,"Effects of 17?-ethynylestradiol on sexual differentiation and development of the African clawed frog (Xenopus laevis).","22692001","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,0,"4195806",1970,"46, XY female: anti-androgenic effect of oral contraceptive?","4195806","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",0,1,"4206854",1974,"[Effects of ethynil estradiol and of androgens on the parameters of thyroid function in the syndrome of male pseudohermaphroditism with testicular feminization].","4206854","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",0,0,"5373825",1969,"[Cytohormonal vaginal effects of methoxy-ethinylestradiol and lynestrenol therapy in artificial menstrual cycle].","5373825","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",0,1,"589801",1977,"Failure of positive feedback in normal men and subjects with testicular feminization.","589801","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Disorders of Sex Development",1,1,"8784065",1996,"Lactotroph hyperplasia in an estrogen treated male-to-female transsexual patient.","8784065","Ethinyl Estradiol","Disorders of Sex Development",1,null,1]
["Ethinyl Estradiol","Epididymis",1,1,"10453912",1999,"Epididymal sperm motion as a parameter of male reproductive toxicity: sperm motion, fertility, and histopathology in ethinylestradiol-treated rats.","10453912","Ethinyl Estradiol","Epididymis",1,null,1]
["Ethinyl Estradiol","Epididymis",0,1,"11331650",2001,"Altered prostate growth and daily sperm production in male mice exposed prenatally to subclinical doses of 17alpha-ethinyl oestradiol.","11331650","Ethinyl Estradiol","Epididymis",1,null,1]
["Ethinyl Estradiol","Epididymis",1,1,"15219631",2004,"Lack of modifying effects of genistein on disruption of the reproductive system by perinatal dietary exposure to ethinylestradiol in rats.","15219631","Ethinyl Estradiol","Epididymis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3012,I3012)","v":"Ethinyl Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3012,J3012)","v":"Epididymis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3012,H3012)","v":"15808799"},2005,"Insights into testicular damage induced by ethinylestradiol in rats.","15808799","Ethinyl Estradiol","Epididymis",1,null,1]
["Ethinyl Estradiol","Epididymis",1,1,"15901920",2005,"Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A.","15901920","Ethinyl Estradiol","Epididymis",1,null,1]
["Ethinyl Estradiol","Epididymis",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","Ethinyl Estradiol","Epididymis",1,null,1]
["Ethinyl Estradiol","Epididymis",0,1,"3189459",1988,"Long-term effects on male reproductive organs of prenatal exposure to ethinyl estradiol.","3189459","Ethinyl Estradiol","Epididymis",1,null,1]
["Ethinyl Estradiol","Epididymis",0,1,"4035583",1985,"Effect of ethinyl estradiol on the differentiation of mouse fetal testis.","4035583","Ethinyl Estradiol","Epididymis",1,null,1]
["Ethinyl Estradiol","Epididymis",0,1,"736678",1978,"Endocrinological and physiological features after steroid treatment of male rats.","736678","Ethinyl Estradiol","Epididymis",1,null,1]
["Ethinyl Estradiol","Genitalia, Male",1,1,"12062934",2002,"Changes of serum alpha 2u-globulin in the subacute oral toxicity study of ethynyl estradiol and bisphenol A based on the draft protocol for the 'Enhanced OECD Test Guideline No. 407'.","12062934","Ethinyl Estradiol","Genitalia, Male",1,null,1]
["Ethinyl Estradiol","Genitalia, Male",0,1,"16945680",2006,"Ontogeny of androgen receptor and disruption of its mRNA expression by exogenous estrogens during morphogenesis of the genital tubercle.","16945680","Ethinyl Estradiol","Genitalia, Male",1,null,1]
["Ethinyl Estradiol","Genitalia, Male",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","Ethinyl Estradiol","Genitalia, Male",1,null,1]
["Ethinyl Estradiol","Genitalia, Male",0,1,"3189459",1988,"Long-term effects on male reproductive organs of prenatal exposure to ethinyl estradiol.","3189459","Ethinyl Estradiol","Genitalia, Male",1,null,1]
["Ethinyl Estradiol","Genitalia, Male",0,1,"736678",1978,"Endocrinological and physiological features after steroid treatment of male rats.","736678","Ethinyl Estradiol","Genitalia, Male",1,null,1]
["Ethinyl Estradiol","Genitalia, Male",0,1,"7401044",1980,"Long-term effects of prenatal oestrogen treatment on genital morphology and reproductive function in the rat.","7401044","Ethinyl Estradiol","Genitalia, Male",1,null,1]
["Ethinyl Estradiol","Genitalia, Male",1,1,"8667452",1995,"Male reproductive toxicity of ethinylestradiol associated with 4 weeks daily dosing prior to mating in rats.","8667452","Ethinyl Estradiol","Genitalia, Male",1,null,1]
["Ethinyl Estradiol","Gonadal Dysgenesis",0,0,"4039732",1985,"Somatomedin-C levels in children and adolescents with gonadal dysgenesis: differences from age-matched normal females and effect of chronic estrogen replacement therapy.","4039732","Ethinyl Estradiol","Gonadal Dysgenesis",1,null,1]
["Ethinyl Estradiol","Gonadal Dysgenesis",1,1,"4049280",1985,"Gonadal dysgenesis induced by prenatal exposure to ethinyl estradiol in mice.","4049280","Ethinyl Estradiol","Gonadal Dysgenesis",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",1,0,"11229194",1997,"Development of diabetes mellitus and hypertension due to aggravation of insulin resistance after estrogen--progestogen in HAIR-AN syndrome.","11229194","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"12195232",2002,"Cyproterone acetate-ethinyl estradiol treatment alters urinary 6-sulfatoxymelatonin excretion in hyperandrogenic women.","12195232","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"15031776",2004,"Urinary 6-sulfatoxymelatonin excretion in hyperandrogenic women: the effect of cyproterone acetate-ethinyl estradiol treatment.","15031776","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"15356085",2004,"Flutamide-metformin plus ethinylestradiol-drospirenone for lipolysis and antiatherogenesis in young women with ovarian hyperandrogenism: the key role of early, low-dose flutamide.","15356085","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"15483105",2005,"Flutamide-metformin plus ethinylestradiol-drospirenone for lipolysis and antiatherogenesis in young women with ovarian hyperandrogenism: the key role of metformin at the start and after more than one year of therapy.","15483105","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"17056444",2006,"Metabolic and clinical effects of progestogens.","17056444","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"17418832",2007,"Evaluation of effects of an oral contraceptive containing ethinylestradiol combined with drospirenone on adrenal steroidogenesis in hyperandrogenic women with polycystic ovary syndrome.","17418832","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"18547986",2008,"[Effect on skin and hormonal hyperandrogenic manifestations of an oral estroprogestin association containing ethynilestradiol 30 mg and drospirenone 3 mg].","18547986","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"18608522",2008,"Effects of metformin and ethinyl estradiol-cyproterone acetate on clinical, endocrine and metabolic factors in women with polycystic ovary syndrome.","18608522","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",1,0,"19019358",2010,"Endothelial function and insulin resistance in polycystic ovary syndrome: the effects of medical therapy.","19019358","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"19172543",2008,"Effects of two estroprogestins containing ethynilestradiol 30 microg and drospirenone 3 mg and ethynilestradiol 30 microg and chlormadinone 2 mg on skin and hormonal hyperandrogenic manifestations.","19172543","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"20528210",2011,"Divergent effects of ethinylestradiol-drospirenone and flutamide-metformin on follistatin in adolescents and women with hyperinsulinemic androgen excess.","20528210","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"20705157",2010,"Effect of oral contraceptives on markers of hyperandrogenism and SHBG in women with polycystic ovary syndrome.","20705157","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"21079572",2010,"[Short-term effect of an estroprogestin containing ethinylestradiol 20 mcg + drospirenone 3 mg in 24+4 regimen at hormonal and cutaneous level in ovarian hyperandrogenism].","21079572","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"21325466",2011,"Drospirenone/ethinyl estradiol versus rosiglitazone treatment in overweight adolescents with polycystic ovary syndrome: comparison of metabolic, hormonal, and cardiovascular risk factors.","21325466","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"21374929",2010,"[Hormonal treatment effectivity in hyperandrogenic syndrome].","21374929","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"21865363",2011,"Treatment of androgen excess in adolescent girls: ethinylestradiol-cyproteroneacetate versus low-dose pioglitazone-flutamide-metformin.","21865363","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",1,0,"22329763",2012,"17-Hydroxysteroid dehydrogenase type 5 gene polymorphism (-71A/G HSD17B5 SNP) and treatment with oral contraceptive pills in PCOS women without metabolic comorbidities.","22329763","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"22791755",2012,"Ethinyl estradiol-cyproterone acetate versus low-dose pioglitazone-flutamide-metformin for adolescent girls with androgen excess: divergent effects on CD163, TWEAK receptor, ANGPTL4, and LEPTIN expression in subcutaneous adipose tissue.","22791755","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",1,0,"23547047",2013,"Oral contraception vs insulin sensitization for 18 months in nonobese adolescents with androgen excess: posttreatment differences in C-reactive protein, intima-media thickness, visceral adiposity, insulin sensitivity, and menstrual regularity.","23547047","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"24105072",2013,"Clinical efficacy and metabolic impact of two different dosages of ethinyl-estradiol in association with drospirenone in normal-weight women with polycystic ovary syndrome: a randomized study.","24105072","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"8150899",1993,"The induction of ovulation with pulsatile gonadotrophin-releasing hormone (GnRH) administration in hyperandrogenic women after down-regulation with buserelin or suppression with an oral contraceptive.","8150899","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"8200468",1994,"Efficacy on hyperandrogenism and safety of a new oral contraceptive biphasic formulation containing desogestrel.","8200468","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"9098476",1995,"Treatment of female hyperandrogenism: estroprogestinic therapy at low dose in an inversal sequential scheme.","9098476","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hyperandrogenism",0,0,"9126004",1997,"Successful treatment of hirsutism in HAIR-AN syndrome using flutamide, spironolactone, and birth control therapy.","9126004","Ethinyl Estradiol","Hyperandrogenism",1,null,1]
["Ethinyl Estradiol","Hypospadias",0,1,"16569931",2006,"Activating transcription factor 3 is estrogen-responsive in utero and upregulated during sexual differentiation.","16569931","Ethinyl Estradiol","Hypospadias",1,null,1]
["Ethinyl Estradiol","Hypospadias",0,1,"16945680",2006,"Ontogeny of androgen receptor and disruption of its mRNA expression by exogenous estrogens during morphogenesis of the genital tubercle.","16945680","Ethinyl Estradiol","Hypospadias",1,null,1]
["Ethinyl Estradiol","Klinefelter Syndrome",0,0,"14130828",1964,"THE HORMONES AND PUBERTY.","14130828","Ethinyl Estradiol","Klinefelter Syndrome",1,null,1]
["Ethinyl Estradiol","Klinefelter Syndrome",0,1,"4479709",1974,"The effect of oestrogen administration on plasma testosterone, FSH and LH levels in patients with Klinefelter's syndrome and normal men.","4479709","Ethinyl Estradiol","Klinefelter Syndrome",1,null,1]
["Ethinyl Estradiol","Klinefelter Syndrome",1,1,"8784065",1996,"Lactotroph hyperplasia in an estrogen treated male-to-female transsexual patient.","8784065","Ethinyl Estradiol","Klinefelter Syndrome",1,null,1]
["Ethinyl Estradiol","Leydig Cells",1,1,"15808799",2005,"Insights into testicular damage induced by ethinylestradiol in rats.","15808799","Ethinyl Estradiol","Leydig Cells",1,null,1]
["Ethinyl Estradiol","Leydig Cells",1,1,"1819550",1991,"Androgen synthesis in human fetal testis exposed in utero to a combination of norethindrone acetate and ethinyl estradiol.","1819550","Ethinyl Estradiol","Leydig Cells",1,null,1]
["Ethinyl Estradiol","Leydig Cells",1,1,"2874623",1986,"Leydig cell hyperplasia in fetal mice treated transplacentally with ethinyl estradiol.","2874623","Ethinyl Estradiol","Leydig Cells",1,null,1]
["Ethinyl Estradiol","Leydig Cells",0,1,"3189459",1988,"Long-term effects on male reproductive organs of prenatal exposure to ethinyl estradiol.","3189459","Ethinyl Estradiol","Leydig Cells",1,null,1]
["Ethinyl Estradiol","Leydig Cells",0,1,"4035583",1985,"Effect of ethinyl estradiol on the differentiation of mouse fetal testis.","4035583","Ethinyl Estradiol","Leydig Cells",1,null,1]
["Ethinyl Estradiol","Penis",0,1,"6136472",1983,"Synthetic sex hormone treatment during pregnancy and androgen receptors of male offspring.","6136472","Ethinyl Estradiol","Penis",1,null,1]
["Ethinyl Estradiol","Prostate",0,1,"11331650",2001,"Altered prostate growth and daily sperm production in male mice exposed prenatally to subclinical doses of 17alpha-ethinyl oestradiol.","11331650","Ethinyl Estradiol","Prostate",1,null,1]
["Ethinyl Estradiol","Prostate",0,0,"14048324",1963,"BIOLOGIC ACTIVITIES OF PROVEST.","14048324","Ethinyl Estradiol","Prostate",1,null,1]
["Ethinyl Estradiol","Prostate",1,1,"15808799",2005,"Insights into testicular damage induced by ethinylestradiol in rats.","15808799","Ethinyl Estradiol","Prostate",1,null,1]
["Ethinyl Estradiol","Prostate",1,1,"15867144",2005,"Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra.","15867144","Ethinyl Estradiol","Prostate",1,null,1]
["Ethinyl Estradiol","Prostate",1,1,"21314741",2011,"Exposure to ethinylestradiol during prenatal development and postnatal supplementation with testosterone causes morphophysiological alterations in the prostate of male and female adult gerbils.","21314741","Ethinyl Estradiol","Prostate",1,null,1]
["Ethinyl Estradiol","Prostate",1,1,"22488762",2012,"Microscopic comparative study of the exposure effects of testosterone cypionate and ethinylestradiol during prenatal life on the prostatic tissue of adult gerbils.","22488762","Ethinyl Estradiol","Prostate",1,null,1]
["Ethinyl Estradiol","Prostate",0,1,"5645534",1968,"The effects of norgestrel, ethinyl estradiol, and their combination, Ovral, on lactation and the offspring of rats treated during lactation.","5645534","Ethinyl Estradiol","Prostate",1,null,1]
["Ethinyl Estradiol","Prostate",0,1,"5952382",1966,"Biological activities of a combination of medroxyprogesterone acetate and ethinyloestradiol.","5952382","Ethinyl Estradiol","Prostate",1,null,1]
["Ethinyl Estradiol","Prostate",0,1,"736678",1978,"Endocrinological and physiological features after steroid treatment of male rats.","736678","Ethinyl Estradiol","Prostate",1,null,1]
["Ethinyl Estradiol","Prostate",0,1,"7401044",1980,"Long-term effects of prenatal oestrogen treatment on genital morphology and reproductive function in the rat.","7401044","Ethinyl Estradiol","Prostate",1,null,1]
["Ethinyl Estradiol","Prostatic Neoplasms",1,1,"21314741",2011,"Exposure to ethinylestradiol during prenatal development and postnatal supplementation with testosterone causes morphophysiological alterations in the prostate of male and female adult gerbils.","21314741","Ethinyl Estradiol","Prostatic Neoplasms",1,null,1]
["Ethinyl Estradiol","Seminal Vesicles",0,1,"11331650",2001,"Altered prostate growth and daily sperm production in male mice exposed prenatally to subclinical doses of 17alpha-ethinyl oestradiol.","11331650","Ethinyl Estradiol","Seminal Vesicles",1,null,1]
["Ethinyl Estradiol","Seminal Vesicles",1,1,"12029382",2002,"Sensitive detection of the endocrine effects of the estrogen analogue ethinylestradiol using a modified enhanced subacute rat study protocol (OECD Test Guideline no. 407).","12029382","Ethinyl Estradiol","Seminal Vesicles",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3076,I3076)","v":"Ethinyl Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3076,J3076)","v":"Seminal Vesicles"},0,0,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3076,H3076)","v":"14048324"},1963,"BIOLOGIC ACTIVITIES OF PROVEST.","14048324","Ethinyl Estradiol","Seminal Vesicles",1,null,1]
["Ethinyl Estradiol","Seminal Vesicles",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","Ethinyl Estradiol","Seminal Vesicles",1,null,1]
["Ethinyl Estradiol","Seminal Vesicles",0,1,"5591968",1967,"[Partial inhibition of the excretion of the luteinizing hormone (LH) in the female urine by anti-ovulatory compounds].","5591968","Ethinyl Estradiol","Seminal Vesicles",1,null,1]
["Ethinyl Estradiol","Seminal Vesicles",0,1,"5645534",1968,"The effects of norgestrel, ethinyl estradiol, and their combination, Ovral, on lactation and the offspring of rats treated during lactation.","5645534","Ethinyl Estradiol","Seminal Vesicles",1,null,1]
["Ethinyl Estradiol","Seminal Vesicles",0,1,"5952382",1966,"Biological activities of a combination of medroxyprogesterone acetate and ethinyloestradiol.","5952382","Ethinyl Estradiol","Seminal Vesicles",1,null,1]
["Ethinyl Estradiol","Seminal Vesicles",0,1,"736678",1978,"Endocrinological and physiological features after steroid treatment of male rats.","736678","Ethinyl Estradiol","Seminal Vesicles",1,null,1]
["Ethinyl Estradiol","Seminiferous Tubules",1,1,"18206232",2008,"Comparison of ethinylestradiol and nonylphenol effects on reproduction of Chinese rare minnows (Gobiocypris rarus).","18206232","Ethinyl Estradiol","Seminiferous Tubules",1,null,1]
["Ethinyl Estradiol","Seminiferous Tubules",1,1,"2876659",1986,"Accelerated differentiation in seminiferous tubules of fetal mice prenatally exposed to ethinyl estradiol.","2876659","Ethinyl Estradiol","Seminiferous Tubules",1,null,1]
["Ethinyl Estradiol","Seminiferous Tubules",0,1,"4035583",1985,"Effect of ethinyl estradiol on the differentiation of mouse fetal testis.","4035583","Ethinyl Estradiol","Seminiferous Tubules",1,null,1]
["Ethinyl Estradiol","Sertoli Cells",1,1,"12584010",2003,"Intrauterine bisphenol A exposure leads to stimulatory effects on Sertoli cell number in rats.","12584010","Ethinyl Estradiol","Sertoli Cells",1,null,1]
["Ethinyl Estradiol","Sertoli Cells",0,1,"4035583",1985,"Effect of ethinyl estradiol on the differentiation of mouse fetal testis.","4035583","Ethinyl Estradiol","Sertoli Cells",1,null,1]
["Ethinyl Estradiol","Sperm Count",0,1,"1387850",1992,"Effects of ethinyl estradiol on semen quality and various hormonal parameters in a eugonadal male.","1387850","Ethinyl Estradiol","Sperm Count",1,null,1]
["Ethinyl Estradiol","Sperm Count",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","Ethinyl Estradiol","Sperm Count",1,null,1]
["Ethinyl Estradiol","Sperm Count",1,1,"19184736",2009,"Xenopus tropicalis as a test system for developmental and reproductive toxicity.","19184736","Ethinyl Estradiol","Sperm Count",1,null,1]
["Ethinyl Estradiol","Sperm Count",1,1,"23160314",2012,"Estrogen-like disruptive effects of dietary exposure to bisphenol A or 17?-ethinyl estradiol in CD1 mice.","23160314","Ethinyl Estradiol","Sperm Count",1,null,1]
["Ethinyl Estradiol","Sperm Head",1,1,"10453912",1999,"Epididymal sperm motion as a parameter of male reproductive toxicity: sperm motion, fertility, and histopathology in ethinylestradiol-treated rats.","10453912","Ethinyl Estradiol","Sperm Head",1,null,1]
["Ethinyl Estradiol","Sperm Motility",1,1,"10453912",1999,"Epididymal sperm motion as a parameter of male reproductive toxicity: sperm motion, fertility, and histopathology in ethinylestradiol-treated rats.","10453912","Ethinyl Estradiol","Sperm Motility",1,null,1]
["Ethinyl Estradiol","Sperm Motility",0,1,"1387850",1992,"Effects of ethinyl estradiol on semen quality and various hormonal parameters in a eugonadal male.","1387850","Ethinyl Estradiol","Sperm Motility",1,null,1]
["Ethinyl Estradiol","Sperm Motility",0,1,"14668003",2003,"Mechanisms of action of emergency contraception.","14668003","Ethinyl Estradiol","Sperm Motility",1,null,1]
["Ethinyl Estradiol","Sperm Motility",0,1,"15325889",2004,"Combined administration of low-dose gossypol acetic acid with desogestrel/mini-dose ethinylestradiol/testosterone undecanoate as an oral contraceptive for men.","15325889","Ethinyl Estradiol","Sperm Motility",1,null,1]
["Ethinyl Estradiol","Sperm Motility",1,1,"18506499",2009,"Effects of ethinylestradiol on medaka (Oryzias latipes) as measured by sperm motility and fertilization success.","18506499","Ethinyl Estradiol","Sperm Motility",1,null,1]
["Ethinyl Estradiol","Sperm Motility",1,1,"19747739",2009,"Disruption of zebrafish (Danio rerio) embryonic development after full life-cycle parental exposure to low levels of ethinylestradiol.","19747739","Ethinyl Estradiol","Sperm Motility",1,null,1]
["Ethinyl Estradiol","Sperm Motility",0,1,"22223459",2014,"Exposure to 17?-ethinylestradiol decreases motility and ATP in sperm of male fighting fish Betta splendens.","22223459","Ethinyl Estradiol","Sperm Motility",1,null,1]
["Ethinyl Estradiol","Sperm Motility",1,1,"24335523",2013,"The effect of 17?-ethynylestradiol on steroidogenesis and gonadal cytokine gene expression is related to the reproductive stage in marine hermaphrodite fish.","24335523","Ethinyl Estradiol","Sperm Motility",1,null,1]
["Ethinyl Estradiol","Spermatids",0,1,"15451339",2004,"A combined regimen of gossypol plus methyltestosterone and ethinylestradiol as a contraceptive induces germ cell apoptosis and expression of its related genes in rats.","15451339","Ethinyl Estradiol","Spermatids",1,null,1]
["Ethinyl Estradiol","Spermatocytes",0,1,"15451339",2004,"A combined regimen of gossypol plus methyltestosterone and ethinylestradiol as a contraceptive induces germ cell apoptosis and expression of its related genes in rats.","15451339","Ethinyl Estradiol","Spermatocytes",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"10453912",1999,"Epididymal sperm motion as a parameter of male reproductive toxicity: sperm motion, fertility, and histopathology in ethinylestradiol-treated rats.","10453912","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",0,1,"11331650",2001,"Altered prostate growth and daily sperm production in male mice exposed prenatally to subclinical doses of 17alpha-ethinyl oestradiol.","11331650","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"12550100",2003,"Effects of 17 alpha-ethinylestradiol on sexual development of the amphipod Hyalella azteca.","12550100","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"12785584",2003,"Short-term exposure to 17 alpha-ethynylestradiol decreases the fertility of sexually maturing male rainbow trout (Oncorhynchus mykiss).","12785584","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",0,1,"12950274",2003,"Effect of 17-alpha-ethynylestradiol on germ cell proliferation in organ and primary culture of medaka (Oryzias latipes) testis.","12950274","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",0,1,"15325889",2004,"Combined administration of low-dose gossypol acetic acid with desogestrel/mini-dose ethinylestradiol/testosterone undecanoate as an oral contraceptive for men.","15325889","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"15808799",2005,"Insights into testicular damage induced by ethinylestradiol in rats.","15808799","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"16002344",2005,"Effects of selected xenoestrogens on liver peroxisomes, vitellogenin levels and spermatogenic cell proliferation in male zebrafish.","16002344","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"19864016",2010,"Gonadal alterations in male eelpout (Zoarces viviparus) exposed to ethinylestradiol and trenbolone separately or in combination.","19864016","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"20356636",2010,"Bcl-2 and Caspase 3 mRNA levels in the testes of gudgeon, Gobio gobio, exposed to ethinylestradiol (EE2).","20356636","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"20821517",2010,"17alpha-ethinylestradiol induces an imbalance between apoptosis and cell proliferation to sex steroid disruption in a testis culture of gudgeon, Gobio gobio.","20821517","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"21821292",2011,"Dietary intake of 17?-ethinylestradiol promotes leukocytes infiltration in the gonad of the hermaphrodite gilthead seabream.","21821292","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"23583938",2013,"Evidence of small modulation of ethinylestradiol induced effects by concurrent exposure to trenbolone in male eelpout Zoarces viviparus.","23583938","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",1,1,"24335523",2013,"The effect of 17?-ethynylestradiol on steroidogenesis and gonadal cytokine gene expression is related to the reproductive stage in marine hermaphrodite fish.","24335523","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",0,1,"3189459",1988,"Long-term effects on male reproductive organs of prenatal exposure to ethinyl estradiol.","3189459","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogenesis",0,1,"736678",1978,"Endocrinological and physiological features after steroid treatment of male rats.","736678","Ethinyl Estradiol","Spermatogenesis",1,null,1]
["Ethinyl Estradiol","Spermatogonia",0,1,"12950274",2003,"Effect of 17-alpha-ethynylestradiol on germ cell proliferation in organ and primary culture of medaka (Oryzias latipes) testis.","12950274","Ethinyl Estradiol","Spermatogonia",1,null,1]
["Ethinyl Estradiol","Spermatogonia",0,1,"17453689",2007,"Gossypol with methyltestosterone and ethinylestradiol male does not affect rat spermatogonial stem cell differentiation.","17453689","Ethinyl Estradiol","Spermatogonia",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"10525362",1999,"The effect of estrogen on the gonads and on in vitro conversion of androstenedione to testosterone, 11-ketotestosterone, and estradiol-17beta in Sparus aurata (Teleostei, Sparidae).","10525362","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"12029382",2002,"Sensitive detection of the endocrine effects of the estrogen analogue ethinylestradiol using a modified enhanced subacute rat study protocol (OECD Test Guideline no. 407).","12029382","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"12062934",2002,"Changes of serum alpha 2u-globulin in the subacute oral toxicity study of ethynyl estradiol and bisphenol A based on the draft protocol for the 'Enhanced OECD Test Guideline No. 407'.","12062934","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,0,"12255249",1966,"Post-coital oral contraception.","12255249","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"1387850",1992,"Effects of ethinyl estradiol on semen quality and various hormonal parameters in a eugonadal male.","1387850","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,0,"14106261",1964,"EFFECT OF SYNTHETIC ORAL GESTAGENS ON CERVICAL MUCUS AND SPERM PENETRATION.","14106261","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"14668003",2003,"Mechanisms of action of emergency contraception.","14668003","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"15451339",2004,"A combined regimen of gossypol plus methyltestosterone and ethinylestradiol as a contraceptive induces germ cell apoptosis and expression of its related genes in rats.","15451339","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"15808799",2005,"Insights into testicular damage induced by ethinylestradiol in rats.","15808799","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"15922671",2005,"Effects of 17alpha-ethynylestradiol on sexual development of male western mosquitofish (Gambusia affinis).","15922671","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"16783621",2006,"Comparison of vitellogenin induction, sex ratio, and gonad morphology between zebrafish and Japanese medaka after exposure to 17alpha-ethinylestradiol and 17beta-trenbolone.","16783621","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"17475347",2007,"Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio).","17475347","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"18453010",2008,"Exposure to 17alpha-ethynylestradiol impairs reproductive functions of both male and female zebrafish (Danio rerio).","18453010","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"19066213",2008,"Aneuploid sperm formation in rainbow trout exposed to the environmental estrogen 17{alpha}-ethynylestradiol.","19066213","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"19184736",2009,"Xenopus tropicalis as a test system for developmental and reproductive toxicity.","19184736","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"22223459",2014,"Exposure to 17?-ethinylestradiol decreases motility and ATP in sperm of male fighting fish Betta splendens.","22223459","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"23160314",2012,"Estrogen-like disruptive effects of dietary exposure to bisphenol A or 17?-ethinyl estradiol in CD1 mice.","23160314","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"24458243",2014,"Effects of the synthetic estrogen 17?-ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata.","24458243","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"4372557",1974,"Oral contraceptive for men.","4372557","Ethinyl Estradiol","Spermatozoa",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3140,I3140)","v":"Ethinyl Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3140,J3140)","v":"Spermatozoa"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3140,H3140)","v":"4577932"},1973,"The use of estrogens as postcoital contraceptive agents. Clinical effectiveness and potential mode of action.","4577932","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"4735315",1973,"Cycle pattern and pregnancy rate following combined clomiphene-estrogen therapy.","4735315","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"5757032",1968,"Effect of norethisterone acetate with or without ethinyl oestradiol on the sialic acid concentration and sperm receptivity of the cervical mucus.","5757032","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"6068018",1967,"Effects of quinestrol on cervical mucus and sperm penetration in patients with cervical hostility.","6068018","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"7297068",1981,"Effects of norgestimate in combination with ethinyl estradiol on cervical mucus.","7297068","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",0,1,"736678",1978,"Endocrinological and physiological features after steroid treatment of male rats.","736678","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Spermatozoa",1,1,"8667452",1995,"Male reproductive toxicity of ethinylestradiol associated with 4 weeks daily dosing prior to mating in rats.","8667452","Ethinyl Estradiol","Spermatozoa",1,null,1]
["Ethinyl Estradiol","Testicular Neoplasms",1,1,"1977467",1990,"The effect of in utero ethinyl oestradiol exposure on the risk of cryptorchid testis and testicular teratoma in mice.","1977467","Ethinyl Estradiol","Testicular Neoplasms",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"10492898",1999,"The avian egg as a test system for endocrine disrupters: effects of diethylstilbestrol and ethynylestradiol on sex organ development.","10492898","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"10525362",1999,"The effect of estrogen on the gonads and on in vitro conversion of androstenedione to testosterone, 11-ketotestosterone, and estradiol-17beta in Sparus aurata (Teleostei, Sparidae).","10525362","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"11331650",2001,"Altered prostate growth and daily sperm production in male mice exposed prenatally to subclinical doses of 17alpha-ethinyl oestradiol.","11331650","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"12505378",2003,"Effects of 17a-ethinylestradiol on the expression of three estrogen-responsive genes and cellular ultrastructure of liver and testes in male zebrafish.","12505378","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"12584010",2003,"Intrauterine bisphenol A exposure leads to stimulatory effects on Sertoli cell number in rats.","12584010","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"12643983",2003,"Effects of exposure to 17alpha-ethinylestradiol during early development on sexual differentiation and induction of vitellogenin in zebrafish (Danio rerio).","12643983","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"12758006",2003,"Developmental estrogenic exposure in zebrafish (Danio rerio): I. Effects on sex ratio and breeding success.","12758006","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"12758007",2003,"Developmental estrogenic exposure in zebrafish (Danio rerio): II. Histological evaluation of gametogenesis and organ toxicity.","12758007","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"12785584",2003,"Short-term exposure to 17 alpha-ethynylestradiol decreases the fertility of sexually maturing male rainbow trout (Oncorhynchus mykiss).","12785584","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"12950274",2003,"Effect of 17-alpha-ethynylestradiol on germ cell proliferation in organ and primary culture of medaka (Oryzias latipes) testis.","12950274","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,0,"14048324",1963,"BIOLOGIC ACTIVITIES OF PROVEST.","14048324","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"15219631",2004,"Lack of modifying effects of genistein on disruption of the reproductive system by perinatal dietary exposure to ethinylestradiol in rats.","15219631","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"15285373",2004,"Alterations to gonadal development and reproductive success in Japanese medaka (Oryzias latipes) exposed to 17alpha-ethinylestradiol.","15285373","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"15325889",2004,"Combined administration of low-dose gossypol acetic acid with desogestrel/mini-dose ethinylestradiol/testosterone undecanoate as an oral contraceptive for men.","15325889","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"15556065",2004,"Life-stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure.","15556065","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"15579420",2004,"Long-term exposure to environmental concentrations of the pharmaceutical ethynylestradiol causes reproductive failure in fish.","15579420","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"15808799",2005,"Insights into testicular damage induced by ethinylestradiol in rats.","15808799","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"15901920",2005,"Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A.","15901920","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"16280416",2006,"Defective reproductive organ morphology and function in domestic rooster embryonically exposed to o,p'-DDT or ethynylestradiol.","16280416","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"16783621",2006,"Comparison of vitellogenin induction, sex ratio, and gonad morphology between zebrafish and Japanese medaka after exposure to 17alpha-ethinylestradiol and 17beta-trenbolone.","16783621","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"16844192",2007,"Histological alternation and vitellogenin induction in adult rare minnow (Gobiocypris rarus) after exposure to ethynylestradiol and nonylphenol.","16844192","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"17699736",2007,"Impaired reproduction in three-spined sticklebacks exposed to ethinyl estradiol as juveniles.","17699736","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"17965256",2007,"Reduced embryonic survival in rainbow trout resulting from paternal exposure to the environmental estrogen 17alpha-ethynylestradiol during late sexual maturation.","17965256","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"18054974",2008,"Assessment of 17alpha-ethinylestradiol effects and underlying mechanisms in a continuous, multigeneration exposure of the Chinese rare minnow (Gobiocypris rarus).","18054974","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"18096570",2008,"Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.","18096570","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"1819550",1991,"Androgen synthesis in human fetal testis exposed in utero to a combination of norethindrone acetate and ethinyl estradiol.","1819550","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"18453010",2008,"Exposure to 17alpha-ethynylestradiol impairs reproductive functions of both male and female zebrafish (Danio rerio).","18453010","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"18453011",2008,"Effects of 4-nonylphenol and 17alpha-ethynylestradiol exposure in the Sydney rock oyster, Saccostrea glomerata: Vitellogenin induction and gonadal development.","18453011","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"19184736",2009,"Xenopus tropicalis as a test system for developmental and reproductive toxicity.","19184736","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"19650224",2009,"17alpha-ethinylestradiol alters reproductive behaviors, circulating hormones, and sexual morphology in male fathead minnows (Pimephales promelas).","19650224","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"20356636",2010,"Bcl-2 and Caspase 3 mRNA levels in the testes of gudgeon, Gobio gobio, exposed to ethinylestradiol (EE2).","20356636","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"20821517",2010,"17alpha-ethinylestradiol induces an imbalance between apoptosis and cell proliferation to sex steroid disruption in a testis culture of gudgeon, Gobio gobio.","20821517","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"21684240",2011,"17?-Ethinyl estradiol affects anxiety and shoaling behavior in adult male zebra fish (Danio rerio).","21684240","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"21821292",2011,"Dietary intake of 17?-ethinylestradiol promotes leukocytes infiltration in the gonad of the hermaphrodite gilthead seabream.","21821292","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"22223459",2014,"Exposure to 17?-ethinylestradiol decreases motility and ATP in sperm of male fighting fish Betta splendens.","22223459","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"22619116",2012,"Development of a molecular biomarker for detecting intersex after exposure of male medaka fish to synthetic estrogen.","22619116","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"23129252",2013,"Developmental disorders and altered gene expression in the tropical clawed frog (Silurana tropicalis) exposed to 17?-ethinylestradiol.","23129252","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"23300682",2012,"Anchoring ethinylestradiol induced gene expression changes with testicular morphology and reproductive function in the medaka.","23300682","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"23583938",2013,"Evidence of small modulation of ethinylestradiol induced effects by concurrent exposure to trenbolone in male eelpout Zoarces viviparus.","23583938","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"24335523",2013,"The effect of 17?-ethynylestradiol on steroidogenesis and gonadal cytokine gene expression is related to the reproductive stage in marine hermaphrodite fish.","24335523","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"2874623",1986,"Leydig cell hyperplasia in fetal mice treated transplacentally with ethinyl estradiol.","2874623","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"2876659",1986,"Accelerated differentiation in seminiferous tubules of fetal mice prenatally exposed to ethinyl estradiol.","2876659","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"3189459",1988,"Long-term effects on male reproductive organs of prenatal exposure to ethinyl estradiol.","3189459","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"3577593",1986,"Effect of centchroman on the genital organs of the offspring of rats when administered during lactation or during the neonatal period: a comparative study with ethynylestradiol and diethylstilbestrol.","3577593","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"4035583",1985,"Effect of ethinyl estradiol on the differentiation of mouse fetal testis.","4035583","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"4049280",1985,"Gonadal dysgenesis induced by prenatal exposure to ethinyl estradiol in mice.","4049280","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"5645534",1968,"The effects of norgestrel, ethinyl estradiol, and their combination, Ovral, on lactation and the offspring of rats treated during lactation.","5645534","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",1,1,"5761248",1968,"[Hyperplasia of the interstitial tissue of the embryonal testis after ingestion of hormonal products by the mother].","5761248","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"5952382",1966,"Biological activities of a combination of medroxyprogesterone acetate and ethinyloestradiol.","5952382","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Testis",0,1,"736678",1978,"Endocrinological and physiological features after steroid treatment of male rats.","736678","Ethinyl Estradiol","Testis",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"10231869",1999,"Combination growth hormone and estrogen increase bone mineralization in girls with Turner syndrome.","10231869","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"10636143",2000,"Use of estrogen in young girls with Turner syndrome: effects on memory.","10636143","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"10792330",2000,"A longitudinal study on bone mineral density until adulthood in girls with Turner's syndrome participating in a growth hormone injection frequency-response trial.","10792330","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"10848879",2000,"Carbohydrate metabolism during growth hormone treatment and after discontinuation of growth hormone treatment in girls with Turner syndrome treated with once or twice daily growth hormone injections.","10848879","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"11124794",2001,"A multicentre trial of recombinant growth hormone and low dose oestrogen in Turner syndrome: near final height analysis.","11124794","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",1,0,"11207628",2001,"Oestrogen replacement in young women with Turner's syndrome.","11207628","Ethinyl Estradiol","Turner Syndrome",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3204,I3204)","v":"Ethinyl Estradiol"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3204,J3204)","v":"Turner Syndrome"},0,0,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3204,H3204)","v":"11207629"},2001,"Choosing an oestrogen replacement therapy in young adult women with Turner syndrome.","11207629","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"11940048",2002,"Poor uterine development in Turner syndrome with oral oestrogen therapy.","11940048","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",1,0,"11994337",2002,"Growth hormone and low dose estrogen in Turner syndrome: results of a United States multi-center trial to near-final height.","11994337","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"14136923",1964,"[CLINICAL DIAGNOSIS AND TREATMENT OF GONADAL DYSGENESIS].","14136923","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"1430092",1992,"Serum growth hormone (GH)-binding protein and insulin-like growth factor-I levels in Turner's syndrome before and during treatment with recombinant human GH and ethinyl estradiol.","1430092","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"16335681",2005,"Influence of hormonal therapy on growth rate and bone age progression in patients with Turner syndrome.","16335681","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"16335682",2005,"[The effect of primary lack of estrogens and the influence of the age at the beginning of estrogen therapy on bone mineral density in patients with Turner's syndrome].","16335682","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"180042",1976,"Testosterone-estradiol-binding globulin in patients with Turner's syndrome: effects of estrogens and acute growth hormone administration.","180042","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",1,0,"21449786",2011,"Growth hormone plus childhood low-dose estrogen in Turner's syndrome.","21449786","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"21449792",2011,"Assessing the value of treatments to increase height.","21449792","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"224633",1979,"Replacement oral ethinyloestradiol therapy for gonadal dysgenesis: growth and adrenal androgen studies.","224633","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"2284161",1990,"Increased hGH production rate after low-dose estrogen therapy in prepubertal girls with Turner's syndrome.","2284161","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"2294126",1990,"Growth-promoting effect of growth hormone and low dose ethinyl estradiol in girls with Turner's syndrome.","2294126","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",1,0,"23603786",2013,"Liver dysfunction in Turner syndrome and its relationship to exogenous oestrogen.","23603786","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",1,0,"2466383",1989,"[Endometrial findings in long-term treatment with synthetic sex steroids in Turner syndrome].","2466383","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"2497615",1989,"Influence of estrogen administration on growth hormone response to GHRH and L-Dopa in patients with Turner's syndrome.","2497615","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"2507569",1989,"Specific, time-dependent actions of low-dose ethinyl estradiol administration on the episodic release of growth hormone, follicle-stimulating hormone, and luteinizing hormone in prepubertal girls with Turner's syndrome.","2507569","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"2751332",1989,"Growth hormone secretion in Turner's syndrome and influence of oxandrolone and ethinyl oestradiol.","2751332","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"3410937",1988,"The effect of short term treatment with growth hormone and ethinyl estradiol on lower leg growth rate in girls with Turner's syndrome.","3410937","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"3537251",1986,"Effect of low doses of estradiol on 6-month growth rates and predicted height in patients with Turner syndrome.","3537251","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"3597706",1987,"Growth in Turner's syndrome: long term treatment with low dose ethinyl estradiol.","3597706","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"3781484",1986,"Serum thymidine activity and somatomedin-C levels in children and adolescents with Turner's syndrome: effect of chronic estrogen and progestogen replacement therapy.","3781484","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"3895799",1985,"Effects of luteinizing hormone-releasing hormone (LRH) upon bioactive and immunoreactive serum LH in patients with Turner's syndrome before and after oestrogen treatment.","3895799","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",1,0,"4853428",1974,"Oestrogen-induced endometrial hyperplasia in gonadal dysgenesis.","4853428","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"5313565",1971,"[Persistency of the cyclic sexual center in a XY gonadal dysgenesis].","5313565","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"6684731",1983,"A preliminary study of the effect of estrogen dose on growth in Turner's syndrome.","6684731","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"6684732",1983,"Toward optimal estrogen-replacement therapy.","6684732","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"6741400",1984,"Influence of oestrogen in high and low doses on plasma steroid concentrations in girls with tall stature and Turner syndrome.","6741400","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"7559861",1995,"Estrogens do not affect whole-body protein metabolism in the prepubertal female.","7559861","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"7584704",1995,"Comparison of transdermal and oral estrogen therapy in girls with Turner's syndrome.","7584704","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"8025411",1994,"Change in speaking fundamental frequency in hormone-treated patients with Turner's syndrome--a longitudinal study of four cases.","8025411","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"8359791",1993,"Psychological aspects of the Canadian randomized controlled trial of human growth hormone and low-dose ethinyl oestradiol in children with Turner syndrome. The Canadian Growth Hormone Advisory Group.","8359791","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"946143",1976,"The interaction of growth hormone, somatomedin and oestrogen in patients with Turner's syndrome.","946143","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"9745426",1998,"Effects of estrogen on nonverbal processing speed and motor function in girls with Turner's syndrome.","9745426","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Turner Syndrome",0,0,"9797854",1998,"Gonadotrophin pulsatility in girls with the Turner syndrome: modulation by exogenous sex steroids.","9797854","Ethinyl Estradiol","Turner Syndrome",1,null,1]
["Ethinyl Estradiol","Urethra",1,1,"15867144",2005,"Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra.","15867144","Ethinyl Estradiol","Urethra",1,null,1]
["Ethinyl Estradiol","Urethra",0,1,"16569931",2006,"Activating transcription factor 3 is estrogen-responsive in utero and upregulated during sexual differentiation.","16569931","Ethinyl Estradiol","Urethra",1,null,1]
["Ethinyl Estradiol","Urethra",1,1,"24036065",2013,"Effects of perinatal ethinyl estradiol exposure in male and female Wistar rats.","24036065","Ethinyl Estradiol","Urethra",1,null,1]
["fenarimol","Spermatogenesis",1,1,"21722721",2011,"Maternal exposure to fenarimol promotes reproductive performance in mouse offspring.","21722721","fenarimol","Spermatogenesis",1,null,1]
["Fenthion","Spermatozoa",0,1,"11480215",2001,"Ultrastructural changes in testis of gobiid fish Glossogobius giuris (Ham) induced by fenthion.","11480215","Fenthion","Spermatozoa",1,1,1]
["Fenthion","Testis",0,1,"11480215",2001,"Ultrastructural changes in testis of gobiid fish Glossogobius giuris (Ham) induced by fenthion.","11480215","Fenthion","Testis",1,1,1]
["fluometuron","Spermatogenesis",1,1,"3758741",1986,"[Determining the maximum permissible exposure level of cotoran in atmospheric air with calculation of its late effects].","3758741","fluometuron","Spermatogenesis",1,null,1]
["Flutamide","Acrosome",1,1,"15135853",2004,"Flutamide induces ultrastructural changes in spermatids and the ectoplasmic specialization between the Sertoli cell and spermatids in mouse testes.","15135853","Flutamide","Acrosome",1,1,1]
["Flutamide","Adrenal Hyperplasia, Congenital",1,1,"10720048",2000,"Flutamide, testolactone, and reduced hydrocortisone dose maintain normal growth velocity and bone maturation despite elevated androgen levels in children with congenital adrenal hyperplasia.","10720048","Flutamide","Adrenal Hyperplasia, Congenital",1,1,1]
["Flutamide","Adrenal Hyperplasia, Congenital",0,0,"12008691",2002,"Treatment with flutamide decreases cortisol clearance: implications for therapy in congenital adrenal hyperplasia.","12008691","Flutamide","Adrenal Hyperplasia, Congenital",1,1,1]
["Flutamide","Adrenal Hyperplasia, Congenital",0,1,"12107224",2002,"Flutamide decreases cortisol clearance in patients with congenital adrenal hyperplasia.","12107224","Flutamide","Adrenal Hyperplasia, Congenital",1,1,1]
["Flutamide","Adrenal Hyperplasia, Congenital",0,1,"15985486",2005,"Circulating antiandrogenic activity in children with congenital adrenal hyperplasia during peroral flutamide treatment.","15985486","Flutamide","Adrenal Hyperplasia, Congenital",1,1,1]
["Flutamide","Adrenal Hyperplasia, Congenital",1,1,"8855797",1996,"A preliminary study of flutamide, testolactone, and reduced hydrocortisone dose in the treatment of congenital adrenal hyperplasia.","8855797","Flutamide","Adrenal Hyperplasia, Congenital",1,1,1]
["Flutamide","Adrenal Hyperplasia, Congenital",0,0,"9091697",1997,"New approaches to the treatment of congenital adrenal hyperplasia.","9091697","Flutamide","Adrenal Hyperplasia, Congenital",1,1,1]
["Flutamide","Androgen-Insensitivity Syndrome",1,1,"1364084",1992,"Disturbed testicular descent in the rat after prenatal exposure to the antiandrogen flutamide.","1364084","Flutamide","Androgen-Insensitivity Syndrome",1,1,1]
["Flutamide","Androgen-Insensitivity Syndrome",0,1,"8690007",1996,"Cytochrome c oxidase in rat adrenal and liver: effects of anti-androgen treatment and studies in testicular feminized rats.","8690007","Flutamide","Androgen-Insensitivity Syndrome",1,1,1]
["Flutamide","Blood-Testis Barrier",1,1,"17244729",2007,"Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice.","17244729","Flutamide","Blood-Testis Barrier",1,1,1]
["Flutamide","Cryptorchidism",1,1,"10198273",1999,"Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.","10198273","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",1,1,"11057551",2000,"Comparative studies of fertility and histologic development of contralateral scrotal testes in two rat models of unilateral cryptorchidism.","11057551","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"11315278",2001,"The biological effect of phthalate esters on transabdominal migration of the testis in fetal rats in comparison with the antiandrogen flutamide.","11315278","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"1356753",1992,"Reversal of flutamide-induced cryptorchidism by prenatal time-specific androgens.","1356753","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",1,1,"1364084",1992,"Disturbed testicular descent in the rat after prenatal exposure to the antiandrogen flutamide.","1364084","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",1,1,"15729007",2004,"Effects of flutamide on sex maturation and behavior of offspring born to female rats treated during late pregnancy.","15729007","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",1,1,"15750944",2005,"Gubernacular cell division in different rodent models of cryptorchidism supports indirect androgenic action via the genitofemoral nerve.","15750944","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",1,1,"15788718",2005,"Changes in androgen-mediated reproductive development in male rat offspring following exposure to a single oral dose of flutamide at different gestational ages.","15788718","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",1,1,"16608089",2006,"[Impact of flutamide on sex differentiation in rats].","16608089","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"1677329",1991,"Effects of flutamide and finasteride on rat testicular descent.","1677329","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"1678699",1991,"Time-specific androgen blockade with flutamide inhibits testicular descent in the rat.","1678699","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"20006020",2009,"The antiandrogen flutamide perturbs inguinoscrotal testicular descent in the rat and suggests a link with mammary development.","20006020","Flutamide","Cryptorchidism",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3268,I3268)","v":"Flutamide"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3268,J3268)","v":"Cryptorchidism"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3268,H3268)","v":"21485540"},2011,"[Establishment of a rat model of flutamide-induced cryptorchidism with remaining gonocytes].","21485540","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"22007488",2011,"[The regulation of T3 on maldeveloped gonocyte (Go) and expression of NCAM in flutamide-induced cryptorchidism rat].","22007488","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"22152882",2011,"The effect of flutamide on expression of androgen and estrogen receptors in the gubernaculum and surrounding structures during testicular descent.","22152882","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"22152883",2011,"Gone with the Wnt: the canonical Wnt signaling axis is present and androgen dependent in the rodent gubernaculum.","22152883","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"7571228",1995,"Flutamide-induced cryptorchidism in the rat is associated with altered gubernacular morphology.","7571228","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"7609135",1995,"Antiandrogen induced cryptorchidism in the pig is associated with failed gubernacular regression and epididymal malformations.","7609135","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",1,1,"7912741",1994,"Capsaicin increases the frequency of cryptorchidism in flutamide-treated rats.","7912741","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"7915761",1994,"Prenatal androgen blockade with flutamide inhibits masculinization of the genitofemoral nerve and testicular descent.","7915761","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",0,1,"7915762",1994,"The effect of flutamide on testicular descent in rats examined by scanning electron microscopy.","7915762","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Cryptorchidism",1,1,"9183680",1997,"The effects of pre- and postnatal exposure to the nonsteroidal antiandrogen flutamide on testis descent and morphology in the Albino Swiss rat.","9183680","Flutamide","Cryptorchidism",1,1,1]
["Flutamide","Ejaculatory Ducts",1,1,"1217898",1975,"The male genital tract and the nipples of male and female offspring of rats given the non-steroidal antiandrogens DIMP and Sch 13521, during pregnancy.","1217898","Flutamide","Ejaculatory Ducts",1,1,1]
["Flutamide","Epididymis",1,1,"10876997",2000,"Repeated dose (28 days) oral toxicity study of flutamide in rats, based on the draft protocol for the 'Enhanced OECD Test Guideline 407' for screening for endocrine-disrupting chemicals.","10876997","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",0,1,"1324152",1992,"Comparison of the effects of the 5 alpha-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital differentiation: dose-response studies.","1324152","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",1,1,"1364084",1992,"Disturbed testicular descent in the rat after prenatal exposure to the antiandrogen flutamide.","1364084","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",1,1,"15788718",2005,"Changes in androgen-mediated reproductive development in male rat offspring following exposure to a single oral dose of flutamide at different gestational ages.","15788718","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",0,1,"1605400",1992,"Effect of flutamide on the physiological status of epididymis and epididymal sperms.","1605400","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",0,1,"1677329",1991,"Effects of flutamide and finasteride on rat testicular descent.","1677329","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",0,1,"1759544",1991,"Comparative effects of chronic administration of the non-steroidal antiandrogens flutamide and Casodex on the reproductive system of the adult male rat.","1759544","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",0,1,"1960735",1991,"Testis and epididymis of the Indian wall lizard (Hemidactylus flaviviridis): effects of flutamide on FSH and testosterone influenced spermatogenesis, Leydig cell, and epididymis.","1960735","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",1,1,"21342526",2011,"Morphological and functional alterations in adult boar epididymis: Effects of prenatal and postnatal administration of flutamide.","21342526","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",0,1,"2948871",1986,"Effects of cyproterone acetate and flutamide on the testis and epididymis of the Indian wall lizard, Hemidactylus flaviviridis (Ruppell).","2948871","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",0,1,"6299041",1983,"Effect of a non-steroidal antiandrogen, flutamide, on the hypothalamo-pituitary axis, genital tract and testis in growing male rats: endocrinological and histological data.","6299041","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",0,1,"7609135",1995,"Antiandrogen induced cryptorchidism in the pig is associated with failed gubernacular regression and epididymal malformations.","7609135","Flutamide","Epididymis",1,1,1]
["Flutamide","Epididymis",1,1,"8789411",1995,"Effects of short-term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice.","8789411","Flutamide","Epididymis",1,1,1]
["Flutamide","Genitalia, Male",1,1,"10198273",1999,"Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.","10198273","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",1,1,"11452136",2001,"Androgen-mediated development in male rat offspring exposed to flutamide in utero: permanence and correlation of early postnatal changes in anogenital distance and nipple retention with malformations in androgen-dependent tissues.","11452136","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",1,1,"11915366",2002,"Effects of perinatal exposure to flutamide on sex hormones and androgen-dependent organs in F1 male rats.","11915366","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",1,1,"1217898",1975,"The male genital tract and the nipples of male and female offspring of rats given the non-steroidal antiandrogens DIMP and Sch 13521, during pregnancy.","1217898","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",0,1,"12954404",2003,"Play, copulation, anatomy, and testosterone in gonadally intact male rats prenatally exposed to flutamide.","12954404","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",1,1,"12974607",2003,"Effects of perinatal exposure to flutamide on sex hormone responsiveness in F1 male rats.","12974607","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",0,1,"1324152",1992,"Comparison of the effects of the 5 alpha-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital differentiation: dose-response studies.","1324152","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",1,1,"15729007",2004,"Effects of flutamide on sex maturation and behavior of offspring born to female rats treated during late pregnancy.","15729007","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",1,1,"15788718",2005,"Changes in androgen-mediated reproductive development in male rat offspring following exposure to a single oral dose of flutamide at different gestational ages.","15788718","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",0,1,"16809447",2006,"Androgen-dependent mechanisms of Wolffian duct development and their perturbation by flutamide.","16809447","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",1,1,"20955783",2011,"Copulatory efficiency and fertility in male rats exposed perinatally to flutamide.","20955783","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",1,1,"22230644",2012,"Impairment on sperm quality and fertility of adult rats after antiandrogen exposure during prepuberty.","22230644","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",0,1,"601169",1977,"Differential effects of the antiandrogen flutamide on aspects of sexual behavior in castrated, androgen-treated male rats.","601169","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",0,1,"6541143",1984,"Effect of flutamide on the testis and accessory sex glands of the musk shrew, Suncus murinus L.","6541143","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",0,1,"8580516",1995,"The abnormal development of male sex organs in the rat using a pure antiandrogen and a 5 alpha-reductase inhibitor during gestation.","8580516","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Genitalia, Male",1,1,"8789411",1995,"Effects of short-term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice.","8789411","Flutamide","Genitalia, Male",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"10065780",1999,"Treatment of hirsutism: comparisons between different antiandrogens with central and peripheral effects.","10065780","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"10599749",1999,"Comment on spironolactone, but not flutamide, administration prevents bone loss in hyperandrogenic women treated with gonadotropin-releasing hormone agonist.","10599749","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",1,0,"10999817",2000,"Treatment of hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism in nonobese, adolescent girls: effect of flutamide.","10999817","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"12008691",2002,"Treatment with flutamide decreases cortisol clearance: implications for therapy in congenital adrenal hyperplasia.","12008691","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"12050266",2002,"Additive effects of insulin-sensitizing and anti-androgen treatment in young, nonobese women with hyperinsulinism, hyperandrogenism, dyslipidemia, and anovulation.","12050266","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"12525441",2003,"Low-dose combination of flutamide, metformin and an oral contraceptive for non-obese, young women with polycystic ovary syndrome.","12525441","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"12788862",2003,"Low-dose flutamide-metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism.","12788862","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"14557446",2003,"Flutamide-metformin therapy to reduce fat mass in hyperinsulinemic ovarian hyperandrogenism: effects in adolescents and in women on third-generation oral contraception.","14557446","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"15356085",2004,"Flutamide-metformin plus ethinylestradiol-drospirenone for lipolysis and antiatherogenesis in young women with ovarian hyperandrogenism: the key role of early, low-dose flutamide.","15356085","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"15483105",2005,"Flutamide-metformin plus ethinylestradiol-drospirenone for lipolysis and antiatherogenesis in young women with ovarian hyperandrogenism: the key role of metformin at the start and after more than one year of therapy.","15483105","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",1,0,"15802316",2005,"Absence of hepatotoxicity after long-term, low-dose flutamide in hyperandrogenic girls and young women.","15802316","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"15905296",2005,"High neutrophil count in girls and women with hyperinsulinaemic hyperandrogenism: normalization with metformin and flutamide overcomes the aggravation by oral contraception.","15905296","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"16239318",2006,"Discontinuous low-dose flutamide-metformin plus an oral or a transdermal contraceptive in patients with hyperinsulinaemic hyperandrogenism: normalizing effects on CRP, TNF-alpha and the neutrophil/lymphocyte ratio.","16239318","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"16407452",2006,"Low-dose flutamide-metformin therapy for hyperinsulinemic hyperandrogenism in non-obese adolescents and women.","16407452","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"16798281",2006,"Low-dose flutamide-metformin therapy for hyperinsulinemic hyperandrogenism in nonobese adolescents and women.","16798281","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",1,0,"16932279",2006,"Long-term, low-dose flutamide does not cause hepatotoxicity in hyperandrogenic women.","16932279","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",1,0,"17299064",2007,"Combined low-dose pioglitazone, flutamide, and metformin for women with androgen excess.","17299064","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"17984247",2007,"Flutamide metformin for post-menarcheal girls with preclinical ovarian androgen excess: evidence for differential response by androgen receptor genotype.","17984247","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"18031315",2008,"Pioglitazone (7.5 mg/day) added to flutamide-metformin in women with androgen excess: additional increments of visfatin and high molecular weight adiponectin.","18031315","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",1,0,"18971896",2008,"[Low-dose flutamide in the treatment of hyperandrogenism in adolescents].","18971896","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",1,0,"19903043",2009,"Hepatotoxicity during low-dose flutamide treatment for hirsutism.","19903043","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"20528210",2011,"Divergent effects of ethinylestradiol-drospirenone and flutamide-metformin on follistatin in adolescents and women with hyperinsulinemic androgen excess.","20528210","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"21376280",2011,"Flutamide for androgen excess: low dose is best.","21376280","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"21865363",2011,"Treatment of androgen excess in adolescent girls: ethinylestradiol-cyproteroneacetate versus low-dose pioglitazone-flutamide-metformin.","21865363","Flutamide","Hyperandrogenism",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3332,I3332)","v":"Flutamide"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3332,J3332)","v":"Hyperandrogenism"},0,0,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3332,H3332)","v":"22791755"},2012,"Ethinyl estradiol-cyproterone acetate versus low-dose pioglitazone-flutamide-metformin for adolescent girls with androgen excess: divergent effects on CD163, TWEAK receptor, ANGPTL4, and LEPTIN expression in subcutaneous adipose tissue.","22791755","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",1,0,"22795685",2012,"Hepatotoxicity with low- and ultralow-dose flutamide: a surveillance study on 203 hyperandrogenic young females.","22795685","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",1,0,"22985946",2012,"Hepatotoxicity with flutamide.","22985946","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"8288741",1993,"The effect of flutamide on pulsatile gonadotrophin secretion in hyperandrogenaemic women.","8288741","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"9126004",1997,"Successful treatment of hirsutism in HAIR-AN syndrome using flutamide, spironolactone, and birth control therapy.","9126004","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"9463180",1997,"[Finasteride and flutamide in the treatment of hirsutism].","9463180","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hyperandrogenism",0,0,"9935128",1999,"Prospective randomized study comparing the long-acting gonadotropin-releasing hormone agonist triptorelin, flutamide, and cyproterone acetate, used in combination with an oral contraceptive, in the treatment of hirsutism.","9935128","Flutamide","Hyperandrogenism",1,1,1]
["Flutamide","Hypospadias",1,1,"14725615",2004,"Valproic acid is known to cause hypospadias in man but does not reduce anogenital distance or causes hypospadias in rats.","14725615","Flutamide","Hypospadias",1,1,1]
["Flutamide","Hypospadias",1,1,"15080058",2004,"[A mouse model of hypospadias induced by flutamide].","15080058","Flutamide","Hypospadias",1,1,1]
["Flutamide","Hypospadias",1,1,"15729007",2004,"Effects of flutamide on sex maturation and behavior of offspring born to female rats treated during late pregnancy.","15729007","Flutamide","Hypospadias",1,1,1]
["Flutamide","Hypospadias",1,1,"16608089",2006,"[Impact of flutamide on sex differentiation in rats].","16608089","Flutamide","Hypospadias",1,1,1]
["Flutamide","Hypospadias",1,1,"8789411",1995,"Effects of short-term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice.","8789411","Flutamide","Hypospadias",1,1,1]
["Flutamide","Leydig Cells",1,1,"17888624",2008,"In vivo and in vitro effects of flutamide and diethylstilbestrol on fetal testicular steroidogenesis in the rat.","17888624","Flutamide","Leydig Cells",1,1,1]
["Flutamide","Leydig Cells",0,1,"19032435",2010,"Short-term antiandrogen flutamide treatment causes structural alterations in somatic cells associated with premature detachment of spermatids in the testis of pubertal and adult guinea pigs.","19032435","Flutamide","Leydig Cells",1,1,1]
["Flutamide","Leydig Cells",0,1,"1960735",1991,"Testis and epididymis of the Indian wall lizard (Hemidactylus flaviviridis): effects of flutamide on FSH and testosterone influenced spermatogenesis, Leydig cell, and epididymis.","1960735","Flutamide","Leydig Cells",1,1,1]
["Flutamide","Leydig Cells",0,1,"22177695",2012,"Prenatal and neonatal exposure to flutamide affects function of Leydig cells in adult boar.","22177695","Flutamide","Leydig Cells",1,1,1]
["Flutamide","Leydig Cells",0,1,"2948871",1986,"Effects of cyproterone acetate and flutamide on the testis and epididymis of the Indian wall lizard, Hemidactylus flaviviridis (Ruppell).","2948871","Flutamide","Leydig Cells",1,1,1]
["Flutamide","Leydig Cells",0,1,"3929515",1985,"Effects of flutamide or of supplementation with testosterone in prepubertal male rats prenatally treated with busulfan.","3929515","Flutamide","Leydig Cells",1,1,1]
["Flutamide","Leydig Cells",0,1,"668637",1978,"Reversible inhibitory effect of the non-steroidal antiandrogen flutamide (SCH 13521) on spermatogenesis in mice.","668637","Flutamide","Leydig Cells",1,1,1]
["Flutamide","Leydig Cells",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Flutamide","Leydig Cells",1,1,1]
["Flutamide","Prostate",1,1,"10620483",1999,"In utero exposure to antiandrogens alters the responsiveness of the prostate to p,p'-DDE in adult rats and may induce prostatic inflammation.","10620483","Flutamide","Prostate",1,1,1]
["Flutamide","Prostate",1,1,"10696777",2000,"Comparative evaluation of a 5-day Hershberger assay utilizing mature male rats and a pubertal male assay for detection of flutamide's antiandrogenic activity.","10696777","Flutamide","Prostate",1,1,1]
["Flutamide","Prostate",1,1,"1217898",1975,"The male genital tract and the nipples of male and female offspring of rats given the non-steroidal antiandrogens DIMP and Sch 13521, during pregnancy.","1217898","Flutamide","Prostate",1,1,1]
["Flutamide","Prostate",0,1,"1324152",1992,"Comparison of the effects of the 5 alpha-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital differentiation: dose-response studies.","1324152","Flutamide","Prostate",1,1,1]
["Flutamide","Prostate",0,1,"1356753",1992,"Reversal of flutamide-induced cryptorchidism by prenatal time-specific androgens.","1356753","Flutamide","Prostate",1,1,1]
["Flutamide","Prostate",0,1,"1605400",1992,"Effect of flutamide on the physiological status of epididymis and epididymal sperms.","1605400","Flutamide","Prostate",1,1,1]
["Flutamide","Prostate",0,1,"16141658",2005,"Evaluation of general behavior, memory, learning performance, and brain sexual differentiation in F1 offspring males of rats treated with flutamide during late gestation.","16141658","Flutamide","Prostate",1,1,1]
["Flutamide","Prostate",0,1,"8580516",1995,"The abnormal development of male sex organs in the rat using a pure antiandrogen and a 5 alpha-reductase inhibitor during gestation.","8580516","Flutamide","Prostate",1,1,1]
["Flutamide","Prostate",1,1,"8789411",1995,"Effects of short-term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice.","8789411","Flutamide","Prostate",1,1,1]
["Flutamide","Prostatic Neoplasms",0,1,"1152158",1975,"Prostatic cancer and SCH-13521: II. Histological alterations and the pituitary gonadal axis.","1152158","Flutamide","Prostatic Neoplasms",1,1,1]
["Flutamide","Prostatic Neoplasms",1,1,"12599226",2003,"Impact of a novel neoadjuvant and adjuvant hormone-deprivation approach on quality of life, voiding function, and sexual function after prostate brachytherapy.","12599226","Flutamide","Prostatic Neoplasms",1,1,1]
["Flutamide","Prostatic Neoplasms",0,1,"22503022",2012,"The influence of testosterone suppression and recovery on sexual function in men with prostate cancer: observations from a prospective study in men undergoing intermittent androgen suppression.","22503022","Flutamide","Prostatic Neoplasms",1,1,1]
["Flutamide","Scrotum",0,1,"20006020",2009,"The antiandrogen flutamide perturbs inguinoscrotal testicular descent in the rat and suggests a link with mammary development.","20006020","Flutamide","Scrotum",1,1,1]
["Flutamide","Scrotum",0,1,"22152882",2011,"The effect of flutamide on expression of androgen and estrogen receptors in the gubernaculum and surrounding structures during testicular descent.","22152882","Flutamide","Scrotum",1,1,1]
["Flutamide","Scrotum",0,1,"22152883",2011,"Gone with the Wnt: the canonical Wnt signaling axis is present and androgen dependent in the rodent gubernaculum.","22152883","Flutamide","Scrotum",1,1,1]
["Flutamide","Scrotum",1,1,"7912741",1994,"Capsaicin increases the frequency of cryptorchidism in flutamide-treated rats.","7912741","Flutamide","Scrotum",1,1,1]
["Flutamide","Seminal Vesicles",1,1,"10696777",2000,"Comparative evaluation of a 5-day Hershberger assay utilizing mature male rats and a pubertal male assay for detection of flutamide's antiandrogenic activity.","10696777","Flutamide","Seminal Vesicles",1,1,1]
["Flutamide","Seminal Vesicles",0,1,"1324152",1992,"Comparison of the effects of the 5 alpha-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital differentiation: dose-response studies.","1324152","Flutamide","Seminal Vesicles",1,1,1]
["Flutamide","Seminal Vesicles",0,1,"1605400",1992,"Effect of flutamide on the physiological status of epididymis and epididymal sperms.","1605400","Flutamide","Seminal Vesicles",1,1,1]
["Flutamide","Seminal Vesicles",0,1,"1759544",1991,"Comparative effects of chronic administration of the non-steroidal antiandrogens flutamide and Casodex on the reproductive system of the adult male rat.","1759544","Flutamide","Seminal Vesicles",1,1,1]
["Flutamide","Seminal Vesicles",0,1,"6299041",1983,"Effect of a non-steroidal antiandrogen, flutamide, on the hypothalamo-pituitary axis, genital tract and testis in growing male rats: endocrinological and histological data.","6299041","Flutamide","Seminal Vesicles",1,1,1]
["Flutamide","Seminal Vesicles",0,1,"668637",1978,"Reversible inhibitory effect of the non-steroidal antiandrogen flutamide (SCH 13521) on spermatogenesis in mice.","668637","Flutamide","Seminal Vesicles",1,1,1]
["Flutamide","Seminal Vesicles",1,1,"8789411",1995,"Effects of short-term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice.","8789411","Flutamide","Seminal Vesicles",1,1,1]
["Flutamide","Seminiferous Tubules",1,1,"17244729",2007,"Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice.","17244729","Flutamide","Seminiferous Tubules",1,1,1]
["Flutamide","Seminiferous Tubules",0,1,"1787450",1991,"Effects of flutamide on testicular involution induced by an antagonist of gonadotrophin-releasing hormone and on stimulation of spermatogenesis by follicle-stimulating hormone in rats.","1787450","Flutamide","Seminiferous Tubules",1,1,1]
["Flutamide","Seminiferous Tubules",0,1,"19032435",2010,"Short-term antiandrogen flutamide treatment causes structural alterations in somatic cells associated with premature detachment of spermatids in the testis of pubertal and adult guinea pigs.","19032435","Flutamide","Seminiferous Tubules",1,1,1]
["Flutamide","Sertoli Cells",0,1,"12943996",2003,"Alteration of lactate production and transport in the adult rat testis exposed in utero to flutamide.","12943996","Flutamide","Sertoli Cells",1,1,1]
["Flutamide","Sertoli Cells",1,1,"15135853",2004,"Flutamide induces ultrastructural changes in spermatids and the ectoplasmic specialization between the Sertoli cell and spermatids in mouse testes.","15135853","Flutamide","Sertoli Cells",1,1,1]
["Flutamide","Sertoli Cells",0,1,"16756952",2006,"Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in the mouse testis.","16756952","Flutamide","Sertoli Cells",1,1,1]
["Flutamide","Sertoli Cells",0,1,"19032435",2010,"Short-term antiandrogen flutamide treatment causes structural alterations in somatic cells associated with premature detachment of spermatids in the testis of pubertal and adult guinea pigs.","19032435","Flutamide","Sertoli Cells",1,1,1]
["Flutamide","Sertoli Cells",0,1,"20392824",2010,"Prenatal plus postnatal exposure to Di(n-Butyl) phthalate and/or flutamide markedly reduces final sertoli cell number in the rat.","20392824","Flutamide","Sertoli Cells",1,1,1]
["Flutamide","Sertoli Cells",0,1,"3929515",1985,"Effects of flutamide or of supplementation with testosterone in prepubertal male rats prenatally treated with busulfan.","3929515","Flutamide","Sertoli Cells",1,1,1]
["Flutamide","Sperm Count",0,1,"1787450",1991,"Effects of flutamide on testicular involution induced by an antagonist of gonadotrophin-releasing hormone and on stimulation of spermatogenesis by follicle-stimulating hormone in rats.","1787450","Flutamide","Sperm Count",1,1,1]
["Flutamide","Sperm Count",1,1,"18762243",2008,"Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.","18762243","Flutamide","Sperm Count",1,1,1]
["Flutamide","Sperm Count",1,1,"20955783",2011,"Copulatory efficiency and fertility in male rats exposed perinatally to flutamide.","20955783","Flutamide","Sperm Count",1,1,1]
["Flutamide","Sperm Count",1,1,"22230644",2012,"Impairment on sperm quality and fertility of adult rats after antiandrogen exposure during prepuberty.","22230644","Flutamide","Sperm Count",1,1,1]
["Flutamide","Sperm Motility",1,1,"10876997",2000,"Repeated dose (28 days) oral toxicity study of flutamide in rats, based on the draft protocol for the 'Enhanced OECD Test Guideline 407' for screening for endocrine-disrupting chemicals.","10876997","Flutamide","Sperm Motility",1,1,1]
["Flutamide","Sperm Motility",1,1,"18762243",2008,"Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.","18762243","Flutamide","Sperm Motility",1,1,1]
["Flutamide","Sperm Motility",1,1,"20955783",2011,"Copulatory efficiency and fertility in male rats exposed perinatally to flutamide.","20955783","Flutamide","Sperm Motility",1,1,1]
["Flutamide","Sperm Motility",1,1,"22230644",2012,"Impairment on sperm quality and fertility of adult rats after antiandrogen exposure during prepuberty.","22230644","Flutamide","Sperm Motility",1,1,1]
["Flutamide","Sperm Motility",0,1,"6541143",1984,"Effect of flutamide on the testis and accessory sex glands of the musk shrew, Suncus murinus L.","6541143","Flutamide","Sperm Motility",1,1,1]
["Flutamide","Spermatids",1,1,"15135853",2004,"Flutamide induces ultrastructural changes in spermatids and the ectoplasmic specialization between the Sertoli cell and spermatids in mouse testes.","15135853","Flutamide","Spermatids",1,1,1]
["Flutamide","Spermatids",0,1,"16481087",2006,"Flutamide depresses expression of cortactin in the ectoplasmic specialization between the Sertoli cells and spermatids in the mouse testis.","16481087","Flutamide","Spermatids",1,1,1]
["Flutamide","Spermatids",0,1,"16756952",2006,"Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in the mouse testis.","16756952","Flutamide","Spermatids",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3396,I3396)","v":"Flutamide"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3396,J3396)","v":"Spermatids"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3396,H3396)","v":"19032435"},2010,"Short-term antiandrogen flutamide treatment causes structural alterations in somatic cells associated with premature detachment of spermatids in the testis of pubertal and adult guinea pigs.","19032435","Flutamide","Spermatids",1,1,1]
["Flutamide","Spermatids",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Flutamide","Spermatids",1,1,1]
["Flutamide","Spermatocytes",1,1,"22307005",2012,"Endosulfan and flutamide impair testicular development in the juvenile Asian catfish, Clarias batrachus.","22307005","Flutamide","Spermatocytes",1,1,1]
["Flutamide","Spermatocytes",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Flutamide","Spermatocytes",1,1,1]
["Flutamide","Spermatogenesis",0,1,"14967920",2003,"Alterations of gene expression in adult male rat testis and pituitary shortly after subacute administration of the antiandrogen flutamide.","14967920","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",1,1,"15525576",2004,"The mitochondrial-dependent pathway is chronically affected in testicular germ cell death in adult rats exposed in utero to anti-androgens.","15525576","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",1,1,"17244729",2007,"Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice.","17244729","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"1759544",1991,"Comparative effects of chronic administration of the non-steroidal antiandrogens flutamide and Casodex on the reproductive system of the adult male rat.","1759544","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"1787450",1991,"Effects of flutamide on testicular involution induced by an antagonist of gonadotrophin-releasing hormone and on stimulation of spermatogenesis by follicle-stimulating hormone in rats.","1787450","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",1,1,"18243649",2008,"Review of the histological effects of the anti-androgen, flutamide, on mouse testis.","18243649","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",1,1,"18762243",2008,"Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.","18762243","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"19032435",2010,"Short-term antiandrogen flutamide treatment causes structural alterations in somatic cells associated with premature detachment of spermatids in the testis of pubertal and adult guinea pigs.","19032435","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",1,1,"19303894",2009,"Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.","19303894","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"1960735",1991,"Testis and epididymis of the Indian wall lizard (Hemidactylus flaviviridis): effects of flutamide on FSH and testosterone influenced spermatogenesis, Leydig cell, and epididymis.","1960735","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"21126777",2011,"Gene expression profiling of the androgen receptor antagonists flutamide and vinclozolin in zebrafish (Danio rerio) gonads.","21126777","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"2948871",1986,"Effects of cyproterone acetate and flutamide on the testis and epididymis of the Indian wall lizard, Hemidactylus flaviviridis (Ruppell).","2948871","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"6299041",1983,"Effect of a non-steroidal antiandrogen, flutamide, on the hypothalamo-pituitary axis, genital tract and testis in growing male rats: endocrinological and histological data.","6299041","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"6314726",1983,"Endocrinological and histological changes induced by flutamide treatment on the hypothalamo-hypophyseal testicular axis of the adult male rat and their incidences on fertility.","6314726","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"6541143",1984,"Effect of flutamide on the testis and accessory sex glands of the musk shrew, Suncus murinus L.","6541143","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"668637",1978,"Reversible inhibitory effect of the non-steroidal antiandrogen flutamide (SCH 13521) on spermatogenesis in mice.","668637","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"7789313",1995,"Rapid protection of rat spermatogenic stem cells against procarbazine by treatment with a gonadotropin-releasing hormone antagonist (Nal-Glu) and an antiandrogen (flutamide).","7789313","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"8603608",1996,"Suppression of mouse spermatogenesis by a gonadotropin-releasing hormone antagonist and antiandrogen: failure to protect against radiation-induced gonadal damage.","8603608","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",1,1,"8789411",1995,"Effects of short-term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice.","8789411","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogenesis",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Flutamide","Spermatogenesis",1,1,1]
["Flutamide","Spermatogonia",0,1,"22007488",2011,"[The regulation of T3 on maldeveloped gonocyte (Go) and expression of NCAM in flutamide-induced cryptorchidism rat].","22007488","Flutamide","Spermatogonia",1,1,1]
["Flutamide","Spermatogonia",1,1,"22307005",2012,"Endosulfan and flutamide impair testicular development in the juvenile Asian catfish, Clarias batrachus.","22307005","Flutamide","Spermatogonia",1,1,1]
["Flutamide","Spermatogonia",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Flutamide","Spermatogonia",1,1,1]
["Flutamide","Spermatozoa",1,1,"10876997",2000,"Repeated dose (28 days) oral toxicity study of flutamide in rats, based on the draft protocol for the 'Enhanced OECD Test Guideline 407' for screening for endocrine-disrupting chemicals.","10876997","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",0,1,"1152158",1975,"Prostatic cancer and SCH-13521: II. Histological alterations and the pituitary gonadal axis.","1152158","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",1,1,"15525576",2004,"The mitochondrial-dependent pathway is chronically affected in testicular germ cell death in adult rats exposed in utero to anti-androgens.","15525576","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",0,1,"1605400",1992,"Effect of flutamide on the physiological status of epididymis and epididymal sperms.","1605400","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",1,1,"18762243",2008,"Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.","18762243","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",1,1,"19303894",2009,"Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.","19303894","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",1,1,"20955783",2011,"Copulatory efficiency and fertility in male rats exposed perinatally to flutamide.","20955783","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",0,1,"22050361",2012,"Administration of flutamide alters sperm ultrastructure, sperm plasma membrane integrity and its stability, and sperm mitochondrial oxidative capability in the boar: in vivo and in vitro approach.","22050361","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",1,1,"22230644",2012,"Impairment on sperm quality and fertility of adult rats after antiandrogen exposure during prepuberty.","22230644","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",0,1,"2948871",1986,"Effects of cyproterone acetate and flutamide on the testis and epididymis of the Indian wall lizard, Hemidactylus flaviviridis (Ruppell).","2948871","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",0,1,"6458560",1981,"Effects of antiandrogens on glycogen metabolism of spermatozoa from caput epididymidis.","6458560","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",0,1,"6541143",1984,"Effect of flutamide on the testis and accessory sex glands of the musk shrew, Suncus murinus L.","6541143","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",0,1,"7789313",1995,"Rapid protection of rat spermatogenic stem cells against procarbazine by treatment with a gonadotropin-releasing hormone antagonist (Nal-Glu) and an antiandrogen (flutamide).","7789313","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",0,1,"8537251",1995,"Hormonal protection from cyclophosphamide-induced inactivation of rat stem spermatogonia.","8537251","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Spermatozoa",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Flutamide","Spermatozoa",1,1,1]
["Flutamide","Testis",1,1,"11057551",2000,"Comparative studies of fertility and histologic development of contralateral scrotal testes in two rat models of unilateral cryptorchidism.","11057551","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"11140822",2000,"A dose-finding study of in utero and lactational exposure to diethylstilboestrol and flutamide in 129/Sv mice.","11140822","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"11315278",2001,"The biological effect of phthalate esters on transabdominal migration of the testis in fetal rats in comparison with the antiandrogen flutamide.","11315278","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"11719706",2001,"Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate.","11719706","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"12538628",2003,"Long-term apoptotic cell death process with increased expression and activation of caspase-3 and -6 in adult rat germ cells exposed in utero to flutamide.","12538628","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"12943996",2003,"Alteration of lactate production and transport in the adult rat testis exposed in utero to flutamide.","12943996","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"1324152",1992,"Comparison of the effects of the 5 alpha-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital differentiation: dose-response studies.","1324152","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"1356753",1992,"Reversal of flutamide-induced cryptorchidism by prenatal time-specific androgens.","1356753","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"1364084",1992,"Disturbed testicular descent in the rat after prenatal exposure to the antiandrogen flutamide.","1364084","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"14967920",2003,"Alterations of gene expression in adult male rat testis and pituitary shortly after subacute administration of the antiandrogen flutamide.","14967920","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"15135853",2004,"Flutamide induces ultrastructural changes in spermatids and the ectoplasmic specialization between the Sertoli cell and spermatids in mouse testes.","15135853","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"15522428",2004,"Characterization of responses to the antiandrogen flutamide in a short-term reproduction assay with the fathead minnow.","15522428","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"15750944",2005,"Gubernacular cell division in different rodent models of cryptorchidism supports indirect androgenic action via the genitofemoral nerve.","15750944","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"15788718",2005,"Changes in androgen-mediated reproductive development in male rat offspring following exposure to a single oral dose of flutamide at different gestational ages.","15788718","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"16481087",2006,"Flutamide depresses expression of cortactin in the ectoplasmic specialization between the Sertoli cells and spermatids in the mouse testis.","16481087","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"16756952",2006,"Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in the mouse testis.","16756952","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"1677329",1991,"Effects of flutamide and finasteride on rat testicular descent.","1677329","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"1678699",1991,"Time-specific androgen blockade with flutamide inhibits testicular descent in the rat.","1678699","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"16909602",2006,"[The effects of flutamide on the full gene expression of early testis development of embryonic period male SD].","16909602","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"1759544",1991,"Comparative effects of chronic administration of the non-steroidal antiandrogens flutamide and Casodex on the reproductive system of the adult male rat.","1759544","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"1787450",1991,"Effects of flutamide on testicular involution induced by an antagonist of gonadotrophin-releasing hormone and on stimulation of spermatogenesis by follicle-stimulating hormone in rats.","1787450","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"17888624",2008,"In vivo and in vitro effects of flutamide and diethylstilbestrol on fetal testicular steroidogenesis in the rat.","17888624","Flutamide","Testis",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3460,I3460)","v":"Flutamide"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3460,J3460)","v":"Testis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3460,H3460)","v":"18243649"},2008,"Review of the histological effects of the anti-androgen, flutamide, on mouse testis.","18243649","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"18762243",2008,"Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.","18762243","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"18772241",2009,"Antiandrogen exposure in utero disrupts expression of desert hedgehog and insulin-like factor 3 in the developing fetal rat testis.","18772241","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"19032435",2010,"Short-term antiandrogen flutamide treatment causes structural alterations in somatic cells associated with premature detachment of spermatids in the testis of pubertal and adult guinea pigs.","19032435","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"19303894",2009,"Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.","19303894","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"19853283",2011,"Connexin 43 gene expression in male and female gonads of porcine offspring following in utero exposure to an anti-androgen, flutamide.","19853283","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"20006020",2009,"The antiandrogen flutamide perturbs inguinoscrotal testicular descent in the rat and suggests a link with mammary development.","20006020","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"20392824",2010,"Prenatal plus postnatal exposure to Di(n-Butyl) phthalate and/or flutamide markedly reduces final sertoli cell number in the rat.","20392824","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"21126777",2011,"Gene expression profiling of the androgen receptor antagonists flutamide and vinclozolin in zebrafish (Danio rerio) gonads.","21126777","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"21457361",2011,"Differential expression of connexin 43 in adult pig testes during normal spermatogenic cycle and after flutamide treatment.","21457361","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"21485540",2011,"[Establishment of a rat model of flutamide-induced cryptorchidism with remaining gonocytes].","21485540","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"22152882",2011,"The effect of flutamide on expression of androgen and estrogen receptors in the gubernaculum and surrounding structures during testicular descent.","22152882","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"22152883",2011,"Gone with the Wnt: the canonical Wnt signaling axis is present and androgen dependent in the rodent gubernaculum.","22152883","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"22307005",2012,"Endosulfan and flutamide impair testicular development in the juvenile Asian catfish, Clarias batrachus.","22307005","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"23571006",2013,"In utero exposure to the anti-androgen flutamide influences connexin 43 and ?-catenin expression in porcine fetal gonads.","23571006","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"24453069",2014,"Effects of the commercial antiandrogen flutamide on the biomarkers of reproduction in male Murray rainbowfish (Melanotaenia fluviatilis).","24453069","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"2948871",1986,"Effects of cyproterone acetate and flutamide on the testis and epididymis of the Indian wall lizard, Hemidactylus flaviviridis (Ruppell).","2948871","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"3929515",1985,"Effects of flutamide or of supplementation with testosterone in prepubertal male rats prenatally treated with busulfan.","3929515","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"6299041",1983,"Effect of a non-steroidal antiandrogen, flutamide, on the hypothalamo-pituitary axis, genital tract and testis in growing male rats: endocrinological and histological data.","6299041","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"6314726",1983,"Endocrinological and histological changes induced by flutamide treatment on the hypothalamo-hypophyseal testicular axis of the adult male rat and their incidences on fertility.","6314726","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"6541143",1984,"Effect of flutamide on the testis and accessory sex glands of the musk shrew, Suncus murinus L.","6541143","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"668637",1978,"Reversible inhibitory effect of the non-steroidal antiandrogen flutamide (SCH 13521) on spermatogenesis in mice.","668637","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"7571228",1995,"Flutamide-induced cryptorchidism in the rat is associated with altered gubernacular morphology.","7571228","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"7609135",1995,"Antiandrogen induced cryptorchidism in the pig is associated with failed gubernacular regression and epididymal malformations.","7609135","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"7789313",1995,"Rapid protection of rat spermatogenic stem cells against procarbazine by treatment with a gonadotropin-releasing hormone antagonist (Nal-Glu) and an antiandrogen (flutamide).","7789313","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"7912741",1994,"Capsaicin increases the frequency of cryptorchidism in flutamide-treated rats.","7912741","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"7915761",1994,"Prenatal androgen blockade with flutamide inhibits masculinization of the genitofemoral nerve and testicular descent.","7915761","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"7915762",1994,"The effect of flutamide on testicular descent in rats examined by scanning electron microscopy.","7915762","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"8527525",1995,"Aberrant hormone balance in fetal autoimmune NZB/W mice following prenatal exposure to testosterone excess or the androgen blocker flutamide.","8527525","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"8789411",1995,"Effects of short-term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice.","8789411","Flutamide","Testis",1,1,1]
["Flutamide","Testis",1,1,"9183680",1997,"The effects of pre- and postnatal exposure to the nonsteroidal antiandrogen flutamide on testis descent and morphology in the Albino Swiss rat.","9183680","Flutamide","Testis",1,1,1]
["Flutamide","Testis",0,1,"9292316",1997,"Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number.","9292316","Flutamide","Testis",1,1,1]
["Flutamide","Vas Deferens",0,1,"1324152",1992,"Comparison of the effects of the 5 alpha-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital differentiation: dose-response studies.","1324152","Flutamide","Vas Deferens",1,1,1]
["folpet","Testis",1,1,"7135891",1982,"[Late sequelae of prolonged phthalan exposure].","7135891","folpet","Testis",1,null,1]
["formamide","Seminal Vesicles",1,1,"9114339",1997,"Reproductive toxicology. Formamide.","9114339","formamide","Seminal Vesicles",1,1,1]
["Glutaral","Cryptorchidism",1,1,"16769324",2006,"Glutaraldehyde-induced bowel injury after laparoscopy.","16769324","Glutaral","Cryptorchidism",1,null,1]
["Glutaral","Spermatocytes",0,1,"9634212",1998,"Visualization of kinetochores and analysis of their refractility in crane-fly spermatocytes after aldehyde fixation.","9634212","Glutaral","Spermatocytes",1,null,1]
["Glutaral","Spermatozoa",0,1,"4218964",1974,"The characterization of a malachite green stainable, glutaraldehyde extractable phospholipid in rabbit spermatozoa.","4218964","Glutaral","Spermatozoa",1,null,1]
["Glutaral","Spermatozoa",0,1,"4219847",1974,"Glutaraldehyde fixation of boar spermatozoa for acrosome evaluation.","4219847","Glutaral","Spermatozoa",1,null,1]
["Glutaral","Testis",1,1,"16769324",2006,"Glutaraldehyde-induced bowel injury after laparoscopy.","16769324","Glutaral","Testis",1,null,1]
["glycidol","Spermatogenesis",1,1,"8519528",1995,"Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes.","8519528","glycidol","Spermatogenesis",1,null,1]
["iprodione","Genitalia, Male",1,1,"10188194",1999,"Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat.","10188194","iprodione","Genitalia, Male",1,null,1]
["irgarol 1051","Spermatozoa",1,1,"16446998",2006,"Toxic effects of irgarol and diuron on sea urchin Paracentrotus lividus early development, fertilization, and offspring quality.","16446998","irgarol 1051","Spermatozoa",1,null,1]
["irgarol 1051","Spermatozoa",1,1,"17805469",2008,"Predictability of copper, irgarol, and diuron combined effects on sea urchin Paracentrotus lividus.","17805469","irgarol 1051","Spermatozoa",1,null,1]
["irgarol 1051","Spermatozoa",1,1,"23727205",2013,"Environmental concentrations of irgarol, diuron and S-metolachlor induce deleterious effects on gametes and embryos of the Pacific oyster, Crassostrea gigas.","23727205","irgarol 1051","Spermatozoa",1,null,1]
["Linuron","Epididymis",1,1,"11752686",2002,"Male rats exposed to linuron in utero exhibit permanent changes in anogenital distance, nipple retention, and epididymal malformations that result in subsequent testicular atrophy.","11752686","Linuron","Epididymis",1,1,1]
["Linuron","Epididymis",1,1,"11955944",2002,"Effects of in utero linuron exposure on rat Wolffian duct development.","11955944","Linuron","Epididymis",1,1,1]
["Linuron","Epididymis",1,1,"12730624",2003,"Altered gene expression during rat Wolffian duct development in response to in utero exposure to the antiandrogen linuron.","12730624","Linuron","Epididymis",1,1,1]
["Linuron","Genitalia, Male",1,1,"10910998",2000,"Cellular and molecular mechanisms of action of linuron: an antiandrogenic herbicide that produces reproductive malformations in male rats.","10910998","Linuron","Genitalia, Male",1,1,1]
["Linuron","Genitalia, Male",1,1,"10964759",2000,"Effects of in utero exposure to linuron on androgen-dependent reproductive development in the male Crl:CD(SD)BR rat.","10964759","Linuron","Genitalia, Male",1,1,1]
["Linuron","Genitalia, Male",1,1,"11752686",2002,"Male rats exposed to linuron in utero exhibit permanent changes in anogenital distance, nipple retention, and epididymal malformations that result in subsequent testicular atrophy.","11752686","Linuron","Genitalia, Male",1,1,1]
["Linuron","Genitalia, Male",0,1,"15286035",2004,"A mixture of the \"antiandrogens\" linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion.","15286035","Linuron","Genitalia, Male",1,1,1]
["Linuron","Leydig Cells",1,1,"19167474",2009,"The herbicide linuron reduces testosterone production from the fetal rat testis during both in utero and in vitro exposures.","19167474","Linuron","Leydig Cells",1,1,1]
["Linuron","Penis",1,1,"11752686",2002,"Male rats exposed to linuron in utero exhibit permanent changes in anogenital distance, nipple retention, and epididymal malformations that result in subsequent testicular atrophy.","11752686","Linuron","Penis",1,1,1]
["Linuron","Testis",1,1,"11752686",2002,"Male rats exposed to linuron in utero exhibit permanent changes in anogenital distance, nipple retention, and epididymal malformations that result in subsequent testicular atrophy.","11752686","Linuron","Testis",1,1,1]
["Linuron","Testis",1,1,"11955944",2002,"Effects of in utero linuron exposure on rat Wolffian duct development.","11955944","Linuron","Testis",1,1,1]
["Linuron","Testis",1,1,"12730624",2003,"Altered gene expression during rat Wolffian duct development in response to in utero exposure to the antiandrogen linuron.","12730624","Linuron","Testis",1,1,1]
["Linuron","Testis",0,1,"15286035",2004,"A mixture of the \"antiandrogens\" linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion.","15286035","Linuron","Testis",1,1,1]
["Linuron","Testis",1,1,"19167474",2009,"The herbicide linuron reduces testosterone production from the fetal rat testis during both in utero and in vitro exposures.","19167474","Linuron","Testis",1,1,1]
["Malathion","Epididymis",1,1,"18831386",2008,"Effect of malathion on reproductive system of male rats.","18831386","Malathion","Epididymis",1,null,1]
["Malathion","Epididymis",1,1,"19442699",2009,"Malathion-induced testicular toxicity in male rats and the protective effect of vitamins C and E.","19442699","Malathion","Epididymis",1,null,1]
["Malathion","Epididymis",1,1,"9087763",1996,"Effect of an organophosphorate insecticide on the testis, epididymis and preimplantational development and pregnancy outcome in mice.","9087763","Malathion","Epididymis",1,null,1]
["Malathion","Leydig Cells",0,1,"1190504",1975,"[The effect of perorally administered DDVP and malathion on spermatogenesis and Leydig cells in the juvenile rat].","1190504","Malathion","Leydig Cells",1,null,1]
["Malathion","Leydig Cells",0,1,"1260153",1976,"Damage to spermatogenesis in juvenile rat treated with DDVP and malathion.","1260153","Malathion","Leydig Cells",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3524,I3524)","v":"Malathion"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3524,J3524)","v":"Seminiferous Tubules"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3524,H3524)","v":"12778319"},2003,"Effect of a single dose of malathion on spermatogenesis in mice.","12778319","Malathion","Seminiferous Tubules",1,null,1]
["Malathion","Sperm Count",0,1,"12778319",2003,"Effect of a single dose of malathion on spermatogenesis in mice.","12778319","Malathion","Sperm Count",1,null,1]
["Malathion","Sperm Count",1,1,"18831386",2008,"Effect of malathion on reproductive system of male rats.","18831386","Malathion","Sperm Count",1,null,1]
["Malathion","Sperm Count",1,1,"19442699",2009,"Malathion-induced testicular toxicity in male rats and the protective effect of vitamins C and E.","19442699","Malathion","Sperm Count",1,null,1]
["Malathion","Sperm Count",1,1,"22177304",2011,"[Synergistic effect of dichlorvos, dimethoate and malathion mixture on reproduction toxicity in male mice].","22177304","Malathion","Sperm Count",1,null,1]
["Malathion","Sperm Motility",1,1,"19442699",2009,"Malathion-induced testicular toxicity in male rats and the protective effect of vitamins C and E.","19442699","Malathion","Sperm Motility",1,null,1]
["Malathion","Sperm Motility",1,1,"22177304",2011,"[Synergistic effect of dichlorvos, dimethoate and malathion mixture on reproduction toxicity in male mice].","22177304","Malathion","Sperm Motility",1,null,1]
["Malathion","Spermatids",0,1,"1190504",1975,"[The effect of perorally administered DDVP and malathion on spermatogenesis and Leydig cells in the juvenile rat].","1190504","Malathion","Spermatids",1,null,1]
["Malathion","Spermatocytes",0,1,"1190504",1975,"[The effect of perorally administered DDVP and malathion on spermatogenesis and Leydig cells in the juvenile rat].","1190504","Malathion","Spermatocytes",1,null,1]
["Malathion","Spermatocytes",0,1,"1260153",1976,"Damage to spermatogenesis in juvenile rat treated with DDVP and malathion.","1260153","Malathion","Spermatocytes",1,null,1]
["Malathion","Spermatocytes",0,1,"3343978",1988,"Cytogenetic effects of malathion insecticide on somatic and germ cells of mice.","3343978","Malathion","Spermatocytes",1,null,1]
["Malathion","Spermatogenesis",0,1,"1190504",1975,"[The effect of perorally administered DDVP and malathion on spermatogenesis and Leydig cells in the juvenile rat].","1190504","Malathion","Spermatogenesis",1,null,1]
["Malathion","Spermatogenesis",0,1,"1260153",1976,"Damage to spermatogenesis in juvenile rat treated with DDVP and malathion.","1260153","Malathion","Spermatogenesis",1,null,1]
["Malathion","Spermatogenesis",0,1,"12778319",2003,"Effect of a single dose of malathion on spermatogenesis in mice.","12778319","Malathion","Spermatogenesis",1,null,1]
["Malathion","Spermatogenesis",1,1,"15685355",2005,"Lepidium meyenii (Maca) reduces spermatogenic damage induced by a single dose of malathion in mice.","15685355","Malathion","Spermatogenesis",1,null,1]
["Malathion","Spermatogenesis",1,1,"7162854",1982,"[Morphological studies of the gonads of male mice receiving insecticides (Metox-30, Sadofos-30 and Foschlor-50)].","7162854","Malathion","Spermatogenesis",1,null,1]
["Malathion","Spermatogonia",0,1,"1190504",1975,"[The effect of perorally administered DDVP and malathion on spermatogenesis and Leydig cells in the juvenile rat].","1190504","Malathion","Spermatogonia",1,null,1]
["Malathion","Spermatogonia",1,1,"7162854",1982,"[Morphological studies of the gonads of male mice receiving insecticides (Metox-30, Sadofos-30 and Foschlor-50)].","7162854","Malathion","Spermatogonia",1,null,1]
["Malathion","Spermatozoa",1,1,"10404127",1999,"Morphological alterations in mouse testis by a single dose of malathion.","10404127","Malathion","Spermatozoa",1,null,1]
["Malathion","Spermatozoa",1,1,"11719084",2002,"Cytogenetic studies on the effect of feeding mice with stored wheat grains treated with malathion.","11719084","Malathion","Spermatozoa",1,null,1]
["Malathion","Spermatozoa",1,1,"11815260",2002,"Genotoxic effects of malathion: an organophosphorus insecticide, using three mammalian bioassays in vivo.","11815260","Malathion","Spermatozoa",1,null,1]
["Malathion","Spermatozoa",0,1,"12778319",2003,"Effect of a single dose of malathion on spermatogenesis in mice.","12778319","Malathion","Spermatozoa",1,null,1]
["Malathion","Spermatozoa",1,1,"15685359",2005,"Effect of malathion on the male reproductive organs of earthworms, Eisenia foetida.","15685359","Malathion","Spermatozoa",1,null,1]
["Malathion","Spermatozoa",1,1,"19148769",2009,"In vitro effect of malathion and diazinon on oocytes fertilization and embryo development in porcine.","19148769","Malathion","Spermatozoa",1,null,1]
["Malathion","Spermatozoa",1,1,"19442699",2009,"Malathion-induced testicular toxicity in male rats and the protective effect of vitamins C and E.","19442699","Malathion","Spermatozoa",1,null,1]
["Malathion","Spermatozoa",1,1,"22177304",2011,"[Synergistic effect of dichlorvos, dimethoate and malathion mixture on reproduction toxicity in male mice].","22177304","Malathion","Spermatozoa",1,null,1]
["Malathion","Spermatozoa",0,1,"234932",1975,"Effects of methoxychlor and malathion on semen characteristics of rams.","234932","Malathion","Spermatozoa",1,null,1]
["Malathion","Spermatozoa",1,1,"7162854",1982,"[Morphological studies of the gonads of male mice receiving insecticides (Metox-30, Sadofos-30 and Foschlor-50)].","7162854","Malathion","Spermatozoa",1,null,1]
["Malathion","Testis",1,1,"10404127",1999,"Morphological alterations in mouse testis by a single dose of malathion.","10404127","Malathion","Testis",1,null,1]
["Malathion","Testis",0,1,"1190504",1975,"[The effect of perorally administered DDVP and malathion on spermatogenesis and Leydig cells in the juvenile rat].","1190504","Malathion","Testis",1,null,1]
["Malathion","Testis",0,1,"1260153",1976,"Damage to spermatogenesis in juvenile rat treated with DDVP and malathion.","1260153","Malathion","Testis",1,null,1]
["Malathion","Testis",1,1,"18831386",2008,"Effect of malathion on reproductive system of male rats.","18831386","Malathion","Testis",1,null,1]
["Malathion","Testis",1,1,"19442699",2009,"Malathion-induced testicular toxicity in male rats and the protective effect of vitamins C and E.","19442699","Malathion","Testis",1,null,1]
["Malathion","Testis",1,1,"24468447",2014,"Gene expression analysis in gonads and brain of catfish Clarias batrachus after the exposure of malathion.","24468447","Malathion","Testis",1,null,1]
["Malathion","Testis",1,1,"6894119",1980,"Effects of two pesticides on testicular 32P uptake, gonadotrophic potency, lipid and cholesterol content of testis, liver and blood serum during spawning phase in Heteropneustes fossilis (Bloch).","6894119","Malathion","Testis",1,null,1]
["Malathion","Testis",1,1,"7162854",1982,"[Morphological studies of the gonads of male mice receiving insecticides (Metox-30, Sadofos-30 and Foschlor-50)].","7162854","Malathion","Testis",1,null,1]
["Malathion","Testis",1,1,"9087763",1996,"Effect of an organophosphorate insecticide on the testis, epididymis and preimplantational development and pregnancy outcome in mice.","9087763","Malathion","Testis",1,null,1]
["Mercuric Chloride","Acrosome",0,1,"16149952",2005,"Bull spermatozoa under mercury stress.","16149952","Mercuric Chloride","Acrosome",1,null,1]
["Mercuric Chloride","Acrosome",0,1,"6667747",1983,"Effects of different fixatives on the development of acrosomal system during spermiogenesis in buffalo, goat and ram.","6667747","Mercuric Chloride","Acrosome",1,null,1]
["Mercuric Chloride","Epididymis",1,1,"22829750",2012,"The effects of chronic ingestion of mercuric chloride on fertility and testosterone levels in male Sprague Dawley rats.","22829750","Mercuric Chloride","Epididymis",1,null,1]
["Mercuric Chloride","Epididymis",1,1,"23555627",2013,"Improvement of mercuric chloride-induced testis injuries and sperm quality deteriorations by Spirulina platensis in rats.","23555627","Mercuric Chloride","Epididymis",1,null,1]
["Mercuric Chloride","Epididymis",1,1,"2741176",1989,"Methylmercury- and mercuric-chloride-induced alterations in rat epididymal sperm.","2741176","Mercuric Chloride","Epididymis",1,null,1]
["Mercuric Chloride","Genitalia, Male",1,1,"11738524",2001,"Protective effect of vitamin E against mercuric chloride reproductive toxicity in male mice.","11738524","Mercuric Chloride","Genitalia, Male",1,null,1]
["Mercuric Chloride","Genitalia, Male",1,1,"8919613",1996,"Reversible effects of mercuric chloride on reproductive organs of the male mouse.","8919613","Mercuric Chloride","Genitalia, Male",1,null,1]
["Mercuric Chloride","Prostate",1,1,"2462528",1988,"[Hygienic evaluation of the gonadotoxic effect of mercury after its combined administration].","2462528","Mercuric Chloride","Prostate",1,null,1]
["Mercuric Chloride","Seminiferous Epithelium",1,1,"1568063",1992,"Action of mercuric chloride during one cycle of seminiferous epithelium in the rat.","1568063","Mercuric Chloride","Seminiferous Epithelium",1,null,1]
["Mercuric Chloride","Seminiferous Tubules",1,1,"23555627",2013,"Improvement of mercuric chloride-induced testis injuries and sperm quality deteriorations by Spirulina platensis in rats.","23555627","Mercuric Chloride","Seminiferous Tubules",1,null,1]
["Mercuric Chloride","Sperm Count",1,1,"11738524",2001,"Protective effect of vitamin E against mercuric chloride reproductive toxicity in male mice.","11738524","Mercuric Chloride","Sperm Count",1,null,1]
["Mercuric Chloride","Sperm Count",0,1,"16149952",2005,"Bull spermatozoa under mercury stress.","16149952","Mercuric Chloride","Sperm Count",1,null,1]
["Mercuric Chloride","Sperm Count",1,1,"1816041",1991,"[Evaluation of combined effects of ionizing radiation and mercury on the reproductive function of animals].","1816041","Mercuric Chloride","Sperm Count",1,null,1]
["Mercuric Chloride","Sperm Count",1,1,"19427169",2009,"Testicular toxicity in mercuric chloride treated rats: association with oxidative stress.","19427169","Mercuric Chloride","Sperm Count",1,null,1]
["Mercuric Chloride","Sperm Count",1,1,"20820944",2011,"Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17?-estradiol level in induction of acute oxidative stress.","20820944","Mercuric Chloride","Sperm Count",1,null,1]
["Mercuric Chloride","Sperm Count",1,1,"22829750",2012,"The effects of chronic ingestion of mercuric chloride on fertility and testosterone levels in male Sprague Dawley rats.","22829750","Mercuric Chloride","Sperm Count",1,null,1]
["Mercuric Chloride","Sperm Count",1,1,"24555655",2014,"Chronic exposure to low doses of mercury impairs sperm quality and induces oxidative stress in rats.","24555655","Mercuric Chloride","Sperm Count",1,null,1]
["Mercuric Chloride","Sperm Count",1,1,"2741176",1989,"Methylmercury- and mercuric-chloride-induced alterations in rat epididymal sperm.","2741176","Mercuric Chloride","Sperm Count",1,null,1]
["Mercuric Chloride","Sperm Count",1,1,"8919613",1996,"Reversible effects of mercuric chloride on reproductive organs of the male mouse.","8919613","Mercuric Chloride","Sperm Count",1,null,1]
["Mercuric Chloride","Sperm Motility",1,1,"1389070",1992,"[Effect of various heavy metals on the ATP content of spermatozoa from Arbacia lixula L.--activity of mercury].","1389070","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Sperm Motility",0,1,"1516536",1992,"[The effect of heavy metals on the in vitro interaction between human sperm and cervical mucus].","1516536","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Sperm Motility",1,1,"1653954",1991,"Effect of organic and inorganic mercury on human sperm motility.","1653954","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Sperm Motility",1,1,"18329842",2008,"Antioxidative potential of melatonin against mercury induced intoxication in spermatozoa in vitro.","18329842","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Sperm Motility",1,1,"19427169",2009,"Testicular toxicity in mercuric chloride treated rats: association with oxidative stress.","19427169","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Sperm Motility",1,1,"1947150",1991,"In vitro exposure of human spermatozoa to mercuric chloride--a histochemical study.","1947150","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Sperm Motility",1,1,"20401773",2010,"In vitro toxicity of mercuric chloride on rabbit spermatozoa motility and cell membrane integrity.","20401773","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Sperm Motility",1,1,"20820944",2011,"Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17?-estradiol level in induction of acute oxidative stress.","20820944","Mercuric Chloride","Sperm Motility",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3588,I3588)","v":"Mercuric Chloride"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3588,J3588)","v":"Sperm Motility"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3588,H3588)","v":"23555627"},2013,"Improvement of mercuric chloride-induced testis injuries and sperm quality deteriorations by Spirulina platensis in rats.","23555627","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Sperm Motility",1,1,"24555655",2014,"Chronic exposure to low doses of mercury impairs sperm quality and induces oxidative stress in rats.","24555655","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Sperm Motility",1,1,"2741176",1989,"Methylmercury- and mercuric-chloride-induced alterations in rat epididymal sperm.","2741176","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Sperm Motility",1,1,"8919613",1996,"Reversible effects of mercuric chloride on reproductive organs of the male mouse.","8919613","Mercuric Chloride","Sperm Motility",1,null,1]
["Mercuric Chloride","Spermatogenesis",1,1,"11480345",2001,"Effect of mercuric chloride on testicular activities in mice, Musculus albinus.","11480345","Mercuric Chloride","Spermatogenesis",1,null,1]
["Mercuric Chloride","Spermatogenesis",1,1,"1568063",1992,"Action of mercuric chloride during one cycle of seminiferous epithelium in the rat.","1568063","Mercuric Chloride","Spermatogenesis",1,null,1]
["Mercuric Chloride","Spermatogenesis",1,1,"1816041",1991,"[Evaluation of combined effects of ionizing radiation and mercury on the reproductive function of animals].","1816041","Mercuric Chloride","Spermatogenesis",1,null,1]
["Mercuric Chloride","Spermatogenesis",1,1,"20820944",2011,"Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17?-estradiol level in induction of acute oxidative stress.","20820944","Mercuric Chloride","Spermatogenesis",1,null,1]
["Mercuric Chloride","Spermatogenesis",1,1,"2462528",1988,"[Hygienic evaluation of the gonadotoxic effect of mercury after its combined administration].","2462528","Mercuric Chloride","Spermatogenesis",1,null,1]
["Mercuric Chloride","Spermatogenesis",1,1,"2741176",1989,"Methylmercury- and mercuric-chloride-induced alterations in rat epididymal sperm.","2741176","Mercuric Chloride","Spermatogenesis",1,null,1]
["Mercuric Chloride","Spermatogenesis",1,1,"3446590",1987,"Effects of mercuric chloride on hydrolytic enzymes of rat testicular tissues.","3446590","Mercuric Chloride","Spermatogenesis",1,null,1]
["Mercuric Chloride","Spermatogenesis",1,1,"3864291",1985,"Inhibition of 3 beta-hydroxy-delta 5-steroid dehydrogenase in rat testicular tissue by mercuric chloride.","3864291","Mercuric Chloride","Spermatogenesis",1,null,1]
["Mercuric Chloride","Spermatogenesis",1,1,"6219726",1983,"Effect of mercuric chloride on the reproductive cycle of the teleostean fish Channa punctatus.","6219726","Mercuric Chloride","Spermatogenesis",1,null,1]
["Mercuric Chloride","Spermatogenesis",0,1,"6667747",1983,"Effects of different fixatives on the development of acrosomal system during spermiogenesis in buffalo, goat and ram.","6667747","Mercuric Chloride","Spermatogenesis",1,null,1]
["Mercuric Chloride","Spermatogonia",1,1,"6224841",1981,"Mutagenicity study on mice given mercuric chloride.","6224841","Mercuric Chloride","Spermatogonia",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"11738524",2001,"Protective effect of vitamin E against mercuric chloride reproductive toxicity in male mice.","11738524","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"1389070",1992,"[Effect of various heavy metals on the ATP content of spermatozoa from Arbacia lixula L.--activity of mercury].","1389070","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",0,1,"1516536",1992,"[The effect of heavy metals on the in vitro interaction between human sperm and cervical mucus].","1516536","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",0,1,"16149952",2005,"Bull spermatozoa under mercury stress.","16149952","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"1653954",1991,"Effect of organic and inorganic mercury on human sperm motility.","1653954","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"18329842",2008,"Antioxidative potential of melatonin against mercury induced intoxication in spermatozoa in vitro.","18329842","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"1947150",1991,"In vitro exposure of human spermatozoa to mercuric chloride--a histochemical study.","1947150","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"20401773",2010,"In vitro toxicity of mercuric chloride on rabbit spermatozoa motility and cell membrane integrity.","20401773","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"23555627",2013,"Improvement of mercuric chloride-induced testis injuries and sperm quality deteriorations by Spirulina platensis in rats.","23555627","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"24555655",2014,"Chronic exposure to low doses of mercury impairs sperm quality and induces oxidative stress in rats.","24555655","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"2741176",1989,"Methylmercury- and mercuric-chloride-induced alterations in rat epididymal sperm.","2741176","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"6519465",1984,"[Embryo- and gonadotoxicity of various halogenated derivatives of inorganic mercury].","6519465","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",0,1,"6667747",1983,"Effects of different fixatives on the development of acrosomal system during spermiogenesis in buffalo, goat and ram.","6667747","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",0,1,"7540052",1995,"High water permeability of human spermatozoa is mercury-resistant and not mediated by CHIP28.","7540052","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Spermatozoa",1,1,"8919613",1996,"Reversible effects of mercuric chloride on reproductive organs of the male mouse.","8919613","Mercuric Chloride","Spermatozoa",1,null,1]
["Mercuric Chloride","Testis",1,1,"11480345",2001,"Effect of mercuric chloride on testicular activities in mice, Musculus albinus.","11480345","Mercuric Chloride","Testis",1,null,1]
["Mercuric Chloride","Testis",1,1,"1816041",1991,"[Evaluation of combined effects of ionizing radiation and mercury on the reproductive function of animals].","1816041","Mercuric Chloride","Testis",1,null,1]
["Mercuric Chloride","Testis",1,1,"19427169",2009,"Testicular toxicity in mercuric chloride treated rats: association with oxidative stress.","19427169","Mercuric Chloride","Testis",1,null,1]
["Mercuric Chloride","Testis",1,1,"20820944",2011,"Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17?-estradiol level in induction of acute oxidative stress.","20820944","Mercuric Chloride","Testis",1,null,1]
["Mercuric Chloride","Testis",1,1,"2462528",1988,"[Hygienic evaluation of the gonadotoxic effect of mercury after its combined administration].","2462528","Mercuric Chloride","Testis",1,null,1]
["Mercuric Chloride","Testis",1,1,"3446590",1987,"Effects of mercuric chloride on hydrolytic enzymes of rat testicular tissues.","3446590","Mercuric Chloride","Testis",1,null,1]
["Mercuric Chloride","Testis",1,1,"3864291",1985,"Inhibition of 3 beta-hydroxy-delta 5-steroid dehydrogenase in rat testicular tissue by mercuric chloride.","3864291","Mercuric Chloride","Testis",1,null,1]
["Mercuric Chloride","Testis",1,1,"6219726",1983,"Effect of mercuric chloride on the reproductive cycle of the teleostean fish Channa punctatus.","6219726","Mercuric Chloride","Testis",1,null,1]
["methamidophos","Epididymis",1,1,"21486422",2012,"Evaluation of male-mediated reproductive toxic effects of methamidophos in the mouse.","21486422","methamidophos","Epididymis",1,1,1]
["methamidophos","Epididymis",0,1,"21843794",2011,"Association of methamidophos and sleep loss on reproductive toxicity of male mice.","21843794","methamidophos","Epididymis",1,1,1]
["methamidophos","Sperm Count",1,1,"10828210",2000,"Paternal effects from methamidophos administration in mice.","10828210","methamidophos","Sperm Count",1,1,1]
["methamidophos","Sperm Count",1,1,"21486422",2012,"Evaluation of male-mediated reproductive toxic effects of methamidophos in the mouse.","21486422","methamidophos","Sperm Count",1,1,1]
["methamidophos","Sperm Motility",1,1,"21486422",2012,"Evaluation of male-mediated reproductive toxic effects of methamidophos in the mouse.","21486422","methamidophos","Sperm Motility",1,1,1]
["methamidophos","Spermatids",1,1,"10828210",2000,"Paternal effects from methamidophos administration in mice.","10828210","methamidophos","Spermatids",1,1,1]
["methamidophos","Spermatozoa",1,1,"10828210",2000,"Paternal effects from methamidophos administration in mice.","10828210","methamidophos","Spermatozoa",1,1,1]
["methamidophos","Spermatozoa",1,1,"21486422",2012,"Evaluation of male-mediated reproductive toxic effects of methamidophos in the mouse.","21486422","methamidophos","Spermatozoa",1,1,1]
["methamidophos","Spermatozoa",0,1,"21843794",2011,"Association of methamidophos and sleep loss on reproductive toxicity of male mice.","21843794","methamidophos","Spermatozoa",1,1,1]
["methamidophos","Spermatozoa",1,1,"23125138",2014,"Comparative effect of technical and commercial formulations of methamidophos on sperm quality and DNA integrity in mice.","23125138","methamidophos","Spermatozoa",1,1,1]
["Methomyl","Sperm Count",1,1,"20813150",2010,"Reproductive toxicity of methomyl insecticide in male rats and protective effect of folic acid.","20813150","Methomyl","Sperm Count",1,1,1]
["Methomyl","Sperm Motility",1,1,"20813150",2010,"Reproductive toxicity of methomyl insecticide in male rats and protective effect of folic acid.","20813150","Methomyl","Sperm Motility",1,1,1]
["Methomyl","Spermatozoa",1,1,"20813150",2010,"Reproductive toxicity of methomyl insecticide in male rats and protective effect of folic acid.","20813150","Methomyl","Spermatozoa",1,1,1]
["Methomyl","Spermatozoa",1,1,"3569177",1987,"Evaluation of lannate 20, a carbamate pesticide in the germ cells of male mice.","3569177","Methomyl","Spermatozoa",1,1,1]
["Methomyl","Testis",1,1,"11516254",2001,"Evaluation of chronic exposure of the male rat reproductive system to the insecticide methomyl.","11516254","Methomyl","Testis",1,1,1]
["Methomyl","Testis",1,1,"20813150",2010,"Reproductive toxicity of methomyl insecticide in male rats and protective effect of folic acid.","20813150","Methomyl","Testis",1,1,1]
["methyl cellosolve","Epididymis",1,1,"11349452",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 27). Repeated toxicity study on ethylene glycol monomethyl ether for 2 and 4 weeks to detect effects on male reproductive organs in rats.","11349452","methyl cellosolve","Epididymis",1,null,1]
["methyl cellosolve","Epididymis",1,1,"1410657",1992,"An abbreviated repeat dose and reproductive/developmental toxicity test for high production volume chemicals.","1410657","methyl cellosolve","Epididymis",1,null,1]
["methyl cellosolve","Epididymis",1,1,"20616209",2010,"Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family.","20616209","methyl cellosolve","Epididymis",1,null,1]
["methyl cellosolve","Epididymis",1,1,"2631294",1989,"Comparative testicular toxicity of bis(2-methoxyethyl) ether and 2-methoxyethanol in rats.","2631294","methyl cellosolve","Epididymis",1,null,1]
["methyl cellosolve","Epididymis",1,1,"9114373",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114373","methyl cellosolve","Epididymis",1,null,1]
["methyl cellosolve","Epididymis",1,1,"9114374",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114374","methyl cellosolve","Epididymis",1,null,1]
["methyl cellosolve","Epididymis",1,1,"9114375",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114375","methyl cellosolve","Epididymis",1,null,1]
["methyl cellosolve","Epididymis",1,1,"9114376",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether: litter five.","9114376","methyl cellosolve","Epididymis",1,null,1]
["methyl cellosolve","Epididymis",1,1,"9114377",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether: litter two.","9114377","methyl cellosolve","Epididymis",1,null,1]
["methyl cellosolve","Genitalia, Male",1,1,"8597649",1995,"Ethylene glycol monomethyl ether effects on health and reproduction in male rabbits.","8597649","methyl cellosolve","Genitalia, Male",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3652,I3652)","v":"methyl cellosolve"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3652,J3652)","v":"Genitalia, Male"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3652,H3652)","v":"9114296"},1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114296","methyl cellosolve","Genitalia, Male",1,null,1]
["methyl cellosolve","Leydig Cells",1,1,"2631294",1989,"Comparative testicular toxicity of bis(2-methoxyethyl) ether and 2-methoxyethanol in rats.","2631294","methyl cellosolve","Leydig Cells",1,null,1]
["methyl cellosolve","Prostate",1,1,"6879608",1983,"Testicular toxicity of ethylene glycol monomethyl and monoethyl ethers in the rat.","6879608","methyl cellosolve","Prostate",1,null,1]
["methyl cellosolve","Prostate",1,1,"9114375",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114375","methyl cellosolve","Prostate",1,null,1]
["methyl cellosolve","Prostate",1,1,"9114377",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether: litter two.","9114377","methyl cellosolve","Prostate",1,null,1]
["methyl cellosolve","Seminal Vesicles",1,1,"6879608",1983,"Testicular toxicity of ethylene glycol monomethyl and monoethyl ethers in the rat.","6879608","methyl cellosolve","Seminal Vesicles",1,null,1]
["methyl cellosolve","Seminal Vesicles",1,1,"9114375",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114375","methyl cellosolve","Seminal Vesicles",1,null,1]
["methyl cellosolve","Seminal Vesicles",1,1,"9114377",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether: litter two.","9114377","methyl cellosolve","Seminal Vesicles",1,null,1]
["methyl cellosolve","Seminiferous Epithelium",1,1,"11349452",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 27). Repeated toxicity study on ethylene glycol monomethyl ether for 2 and 4 weeks to detect effects on male reproductive organs in rats.","11349452","methyl cellosolve","Seminiferous Epithelium",1,null,1]
["methyl cellosolve","Seminiferous Tubules",0,1,"10698670",2000,"Rat testicular Src: normal distribution and involvement in ethylene glycol monomethyl ether-induced apoptosis.","10698670","methyl cellosolve","Seminiferous Tubules",1,null,1]
["methyl cellosolve","Seminiferous Tubules",1,1,"1293015",1992,"Stage specific effect during one seminiferous epithelial cycle following ethylene glycol monomethyl ether exposure in rats.","1293015","methyl cellosolve","Seminiferous Tubules",1,null,1]
["methyl cellosolve","Seminiferous Tubules",1,1,"2136016",1990,"The use of rat in vitro fertilization to detect reductions in the fertility of spermatozoa from males exposed to ethylene glycol monomethyl ether.","2136016","methyl cellosolve","Seminiferous Tubules",1,null,1]
["methyl cellosolve","Seminiferous Tubules",1,1,"2631294",1989,"Comparative testicular toxicity of bis(2-methoxyethyl) ether and 2-methoxyethanol in rats.","2631294","methyl cellosolve","Seminiferous Tubules",1,null,1]
["methyl cellosolve","Sertoli Cells",0,1,"10698670",2000,"Rat testicular Src: normal distribution and involvement in ethylene glycol monomethyl ether-induced apoptosis.","10698670","methyl cellosolve","Sertoli Cells",1,null,1]
["methyl cellosolve","Sertoli Cells",1,1,"2631294",1989,"Comparative testicular toxicity of bis(2-methoxyethyl) ether and 2-methoxyethanol in rats.","2631294","methyl cellosolve","Sertoli Cells",1,null,1]
["methyl cellosolve","Sertoli Cells",1,1,"3792514",1986,"An ultrastructural study of ethylene glycol monomethyl ether-induced spermatocyte injury in the rat.","3792514","methyl cellosolve","Sertoli Cells",1,null,1]
["methyl cellosolve","Sertoli Cells",0,1,"4035690",1985,"Studies on the toxicity of some glycol ethers and alkoxyacetic acids in primary testicular cell cultures.","4035690","methyl cellosolve","Sertoli Cells",1,null,1]
["methyl cellosolve","Sertoli Cells",0,1,"6484991",1984,"The effect of 2-methoxyethanol and methoxyacetic acid on Sertoli cell lactate production and protein synthesis in vitro.","6484991","methyl cellosolve","Sertoli Cells",1,null,1]
["methyl cellosolve","Sertoli Cells",1,1,"9681501",1998,"Rat pachytene spermatocytes down-regulate a polo-like kinase and up-regulate a thiol-specific antioxidant protein, whereas sertoli cells down-regulate a phosphodiesterase and up-regulate an oxidative stress protein after exposure to methoxyethanol and methoxyacetic acid.","9681501","methyl cellosolve","Sertoli Cells",1,null,1]
["methyl cellosolve","Sperm Count",1,1,"11349452",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 27). Repeated toxicity study on ethylene glycol monomethyl ether for 2 and 4 weeks to detect effects on male reproductive organs in rats.","11349452","methyl cellosolve","Sperm Count",1,null,1]
["methyl cellosolve","Sperm Count",1,1,"20616209",2010,"Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family.","20616209","methyl cellosolve","Sperm Count",1,null,1]
["methyl cellosolve","Sperm Count",0,1,"2885937",1987,"Effect of ethylene glycol monomethyl ether on spermatogenesis, dominant lethality, and F1 abnormalities in the rat and the mouse after treatment of F0 males.","2885937","methyl cellosolve","Sperm Count",1,null,1]
["methyl cellosolve","Sperm Count",1,1,"9114374",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114374","methyl cellosolve","Sperm Count",1,null,1]
["methyl cellosolve","Sperm Count",1,1,"9114375",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114375","methyl cellosolve","Sperm Count",1,null,1]
["methyl cellosolve","Sperm Count",1,1,"9114377",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether: litter two.","9114377","methyl cellosolve","Sperm Count",1,null,1]
["methyl cellosolve","Sperm Count",1,1,"9138631",1997,"Disruption of spermatogenesis in rabbits consuming ethylene glycol monomethyl ether.","9138631","methyl cellosolve","Sperm Count",1,null,1]
["methyl cellosolve","Sperm Motility",1,1,"8365589",1993,"Are mouse strains differentially susceptible to the reproductive toxicity of ethylene glycol monomethyl ether? A study of three strains.","8365589","methyl cellosolve","Sperm Motility",1,null,1]
["methyl cellosolve","Sperm Motility",1,1,"9114374",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114374","methyl cellosolve","Sperm Motility",1,null,1]
["methyl cellosolve","Sperm Motility",1,1,"9114377",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether: litter two.","9114377","methyl cellosolve","Sperm Motility",1,null,1]
["methyl cellosolve","Spermatids",1,1,"6705890",1984,"The morphological development of glycol ether-induced testicular atrophy in the rat.","6705890","methyl cellosolve","Spermatids",1,null,1]
["methyl cellosolve","Spermatocytes",1,1,"1293015",1992,"Stage specific effect during one seminiferous epithelial cycle following ethylene glycol monomethyl ether exposure in rats.","1293015","methyl cellosolve","Spermatocytes",1,null,1]
["methyl cellosolve","Spermatocytes",1,1,"19643169",2009,"Testicular gene expression profiling following 2-methoxyethanol and 2-ethoxyethanol exposure in male rats reveals abnormal expression of the actin binding protein cortactin in degenerating spermatocytes.","19643169","methyl cellosolve","Spermatocytes",1,null,1]
["methyl cellosolve","Spermatocytes",1,1,"3738932",1986,"Testicular toxicity of 2-methoxyacetaldehyde, a possible metabolite of ethylene glycol monomethyl ether, in the rat.","3738932","methyl cellosolve","Spermatocytes",1,null,1]
["methyl cellosolve","Spermatocytes",1,1,"3792514",1986,"An ultrastructural study of ethylene glycol monomethyl ether-induced spermatocyte injury in the rat.","3792514","methyl cellosolve","Spermatocytes",1,null,1]
["methyl cellosolve","Spermatocytes",0,1,"4035690",1985,"Studies on the toxicity of some glycol ethers and alkoxyacetic acids in primary testicular cell cultures.","4035690","methyl cellosolve","Spermatocytes",1,null,1]
["methyl cellosolve","Spermatocytes",1,1,"4065311",1985,"A quantitative study of stage-specific spermatocyte damage following administration of ethylene glycol monomethyl ether in the rat.","4065311","methyl cellosolve","Spermatocytes",1,null,1]
["methyl cellosolve","Spermatocytes",1,1,"6705890",1984,"The morphological development of glycol ether-induced testicular atrophy in the rat.","6705890","methyl cellosolve","Spermatocytes",1,null,1]
["methyl cellosolve","Spermatocytes",1,1,"7676444",1995,"Spermatocyte toxicity of 2-methoxyethanol (ME) in rats and guinea pigs: evidence for the induction of apoptosis.","7676444","methyl cellosolve","Spermatocytes",1,null,1]
["methyl cellosolve","Spermatocytes",1,1,"9681501",1998,"Rat pachytene spermatocytes down-regulate a polo-like kinase and up-regulate a thiol-specific antioxidant protein, whereas sertoli cells down-regulate a phosphodiesterase and up-regulate an oxidative stress protein after exposure to methoxyethanol and methoxyacetic acid.","9681501","methyl cellosolve","Spermatocytes",1,null,1]
["methyl cellosolve","Spermatogenesis",1,1,"11349452",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 27). Repeated toxicity study on ethylene glycol monomethyl ether for 2 and 4 weeks to detect effects on male reproductive organs in rats.","11349452","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogenesis",1,1,"1293015",1992,"Stage specific effect during one seminiferous epithelial cycle following ethylene glycol monomethyl ether exposure in rats.","1293015","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogenesis",1,1,"2471289",1989,"Attenuation of 2-methoxyethanol-induced testicular toxicity in the rat by simple physiological compounds.","2471289","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogenesis",1,1,"2631294",1989,"Comparative testicular toxicity of bis(2-methoxyethyl) ether and 2-methoxyethanol in rats.","2631294","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogenesis",0,1,"2885937",1987,"Effect of ethylene glycol monomethyl ether on spermatogenesis, dominant lethality, and F1 abnormalities in the rat and the mouse after treatment of F0 males.","2885937","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogenesis",1,1,"4065311",1985,"A quantitative study of stage-specific spermatocyte damage following administration of ethylene glycol monomethyl ether in the rat.","4065311","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogenesis",0,1,"6484991",1984,"The effect of 2-methoxyethanol and methoxyacetic acid on Sertoli cell lactate production and protein synthesis in vitro.","6484991","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogenesis",1,1,"6705890",1984,"The morphological development of glycol ether-induced testicular atrophy in the rat.","6705890","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogenesis",1,1,"6879608",1983,"Testicular toxicity of ethylene glycol monomethyl and monoethyl ethers in the rat.","6879608","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogenesis",1,1,"8499660",1993,"Ethylene glycol monomethyl ether (EGME) exposure of male mice produces a decrease in cell proliferation of preimplantation embryos.","8499660","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogenesis",1,1,"9138631",1997,"Disruption of spermatogenesis in rabbits consuming ethylene glycol monomethyl ether.","9138631","methyl cellosolve","Spermatogenesis",1,null,1]
["methyl cellosolve","Spermatogonia",0,1,"4035690",1985,"Studies on the toxicity of some glycol ethers and alkoxyacetic acids in primary testicular cell cultures.","4035690","methyl cellosolve","Spermatogonia",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"10689202",2000,"In vitro fertilization after in vivo treatment of rats with three reproductive toxicants.","10689202","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",0,1,"10698670",2000,"Rat testicular Src: normal distribution and involvement in ethylene glycol monomethyl ether-induced apoptosis.","10698670","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"1410657",1992,"An abbreviated repeat dose and reproductive/developmental toxicity test for high production volume chemicals.","1410657","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"20616209",2010,"Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family.","20616209","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"2136016",1990,"The use of rat in vitro fertilization to detect reductions in the fertility of spermatozoa from males exposed to ethylene glycol monomethyl ether.","2136016","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",0,1,"4035690",1985,"Studies on the toxicity of some glycol ethers and alkoxyacetic acids in primary testicular cell cultures.","4035690","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"6623472",1983,"Genetic effects of 2-methoxyethanol and bis(2-methoxyethyl)ether.","6623472","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"6705890",1984,"The morphological development of glycol ether-induced testicular atrophy in the rat.","6705890","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"7859828",1994,"Comparison of the testicular effects of 2-methoxyethanol (ME) in rats and guinea pigs.","7859828","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"8597649",1995,"Ethylene glycol monomethyl ether effects on health and reproduction in male rabbits.","8597649","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"9114373",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114373","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"9114374",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114374","methyl cellosolve","Spermatozoa",1,null,1]
["methyl cellosolve","Spermatozoa",1,1,"9114375",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114375","methyl cellosolve","Spermatozoa",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3716,I3716)","v":"methyl cellosolve"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3716,J3716)","v":"Testis"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3716,H3716)","v":"10698670"},2000,"Rat testicular Src: normal distribution and involvement in ethylene glycol monomethyl ether-induced apoptosis.","10698670","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"11349452",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 27). Repeated toxicity study on ethylene glycol monomethyl ether for 2 and 4 weeks to detect effects on male reproductive organs in rats.","11349452","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"1410657",1992,"An abbreviated repeat dose and reproductive/developmental toxicity test for high production volume chemicals.","1410657","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"19643169",2009,"Testicular gene expression profiling following 2-methoxyethanol and 2-ethoxyethanol exposure in male rats reveals abnormal expression of the actin binding protein cortactin in degenerating spermatocytes.","19643169","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"20616209",2010,"Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family.","20616209","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"2471289",1989,"Attenuation of 2-methoxyethanol-induced testicular toxicity in the rat by simple physiological compounds.","2471289","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"2631294",1989,"Comparative testicular toxicity of bis(2-methoxyethyl) ether and 2-methoxyethanol in rats.","2631294","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",0,1,"2885937",1987,"Effect of ethylene glycol monomethyl ether on spermatogenesis, dominant lethality, and F1 abnormalities in the rat and the mouse after treatment of F0 males.","2885937","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"3738932",1986,"Testicular toxicity of 2-methoxyacetaldehyde, a possible metabolite of ethylene glycol monomethyl ether, in the rat.","3738932","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",0,1,"4035690",1985,"Studies on the toxicity of some glycol ethers and alkoxyacetic acids in primary testicular cell cultures.","4035690","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"6499805",1984,"Further studies on the toxicology of the glycol ethers with emphasis on rapid screening and hazard assessment.","6499805","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"6705890",1984,"The morphological development of glycol ether-induced testicular atrophy in the rat.","6705890","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"6857687",1983,"Comparative aspects of the reproductive toxicology by inhalation in rats of ethylene glycol monomethyl ether and propylene glycol monomethyl ether.","6857687","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"6879608",1983,"Testicular toxicity of ethylene glycol monomethyl and monoethyl ethers in the rat.","6879608","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"7676444",1995,"Spermatocyte toxicity of 2-methoxyethanol (ME) in rats and guinea pigs: evidence for the induction of apoptosis.","7676444","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"7859828",1994,"Comparison of the testicular effects of 2-methoxyethanol (ME) in rats and guinea pigs.","7859828","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"9114373",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114373","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"9114375",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether.","9114375","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"9114376",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether: litter five.","9114376","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"9114377",1997,"Reproductive toxicology. Ethylene glycol monomethyl ether: litter two.","9114377","methyl cellosolve","Testis",1,null,1]
["methyl cellosolve","Testis",1,1,"9138631",1997,"Disruption of spermatogenesis in rabbits consuming ethylene glycol monomethyl ether.","9138631","methyl cellosolve","Testis",1,null,1]
["Methyl Methanesulfonate","Epididymis",1,1,"11349439",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 15). Two-week and 4-week administration study of methyl methanesulfonate (MMS).","11349439","Methyl Methanesulfonate","Epididymis",1,1,1]
["Methyl Methanesulfonate","Epididymis",1,1,"15928457",2005,"A time-course characterization of male reproductive toxicity in rats treated with methyl methanesulphonate (MMS).","15928457","Methyl Methanesulfonate","Epididymis",1,1,1]
["Methyl Methanesulfonate","Epididymis",1,1,"16034192",2005,"Evaluation of testicular toxicity and sperm morphology in rats treated with methyl methanesulphonate (MMS).","16034192","Methyl Methanesulfonate","Epididymis",1,1,1]
["Methyl Methanesulfonate","Epididymis",1,1,"9057872",1997,"Preliminary results of ethylnitrosourea, isopropyl methanesulphonate and methyl methanesulphonate activity in the testis and epididymal spermatozoa of Muta Mice.","9057872","Methyl Methanesulfonate","Epididymis",1,1,1]
["Methyl Methanesulfonate","Epididymis",1,1,"9057873",1997,"Evaluation of the transgenic Lambda/LacI mouse model as a short-term predictor of heritable risk.","9057873","Methyl Methanesulfonate","Epididymis",1,1,1]
["Methyl Methanesulfonate","Epididymis",1,1,"9057875",1997,"Effect of ethylnitrosourea and methyl methanesulfonate on mutation frequency in Muta Mouse germ cells (seminiferous tubule cells and epididymis spermatozoa).","9057875","Methyl Methanesulfonate","Epididymis",1,1,1]
["Methyl Methanesulfonate","Epididymis",1,1,"9057877",1997,"Germ-cell mutagenesis in lambda lacZ transgenic mice treated with ethylating and methylating agents: comparison with specific-locus test.","9057877","Methyl Methanesulfonate","Epididymis",1,1,1]
["Methyl Methanesulfonate","Epididymis",1,1,"9057879",1997,"The activity of ENU, iPMS and MMS in male mouse germ cells using the Muta Mouse positive selection transgenic mutation assay.","9057879","Methyl Methanesulfonate","Epididymis",1,1,1]
["Methyl Methanesulfonate","Epididymis",1,1,"9057880",1997,"Evaluation of lacI mutation in germ cells and micronuclei in peripheral blood after treatment of male lacI transgenic mice with ethylnitrosourea, isopropylmethane sulfonate or methylmethane sulfonate.","9057880","Methyl Methanesulfonate","Epididymis",1,1,1]
["Methyl Methanesulfonate","Epididymis",1,1,"9057881",1997,"Toward an understanding of the use of transgenic mice for the detection of gene mutations in germ cells.","9057881","Methyl Methanesulfonate","Epididymis",1,1,1]
["Methyl Methanesulfonate","Genitalia, Male",0,1,"12463968",2002,"Antifertility effects of methylmethane sulphonate on male reproductive organs of wild Indian house rat: histological and histochemical characteristics.","12463968","Methyl Methanesulfonate","Genitalia, Male",1,1,1]
["Methyl Methanesulfonate","Seminiferous Tubules",0,1,"12463968",2002,"Antifertility effects of methylmethane sulphonate on male reproductive organs of wild Indian house rat: histological and histochemical characteristics.","12463968","Methyl Methanesulfonate","Seminiferous Tubules",1,1,1]
["Methyl Methanesulfonate","Seminiferous Tubules",1,1,"9057873",1997,"Evaluation of the transgenic Lambda/LacI mouse model as a short-term predictor of heritable risk.","9057873","Methyl Methanesulfonate","Seminiferous Tubules",1,1,1]
["Methyl Methanesulfonate","Seminiferous Tubules",1,1,"9057875",1997,"Effect of ethylnitrosourea and methyl methanesulfonate on mutation frequency in Muta Mouse germ cells (seminiferous tubule cells and epididymis spermatozoa).","9057875","Methyl Methanesulfonate","Seminiferous Tubules",1,1,1]
["Methyl Methanesulfonate","Seminiferous Tubules",1,1,"9057878",1997,"Analysis of the mutagenic potential of ENU and MMS in germ cells of male C57BL/6 lacI transgenic mice.","9057878","Methyl Methanesulfonate","Seminiferous Tubules",1,1,1]
["Methyl Methanesulfonate","Seminiferous Tubules",1,1,"9057880",1997,"Evaluation of lacI mutation in germ cells and micronuclei in peripheral blood after treatment of male lacI transgenic mice with ethylnitrosourea, isopropylmethane sulfonate or methylmethane sulfonate.","9057880","Methyl Methanesulfonate","Seminiferous Tubules",1,1,1]
["Methyl Methanesulfonate","Seminiferous Tubules",1,1,"9057881",1997,"Toward an understanding of the use of transgenic mice for the detection of gene mutations in germ cells.","9057881","Methyl Methanesulfonate","Seminiferous Tubules",1,1,1]
["Methyl Methanesulfonate","Seminiferous Tubules",1,1,"9057883",1997,"The detection of gene mutation in the tubular sperm of Muta Mice following a single intraperitoneal treatment with methyl methanesulphonate or ethylnitrosourea.","9057883","Methyl Methanesulfonate","Seminiferous Tubules",1,1,1]
["Methyl Methanesulfonate","Sertoli Cells",1,1,"11349439",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 15). Two-week and 4-week administration study of methyl methanesulfonate (MMS).","11349439","Methyl Methanesulfonate","Sertoli Cells",1,1,1]
["Methyl Methanesulfonate","Sertoli Cells",0,1,"12463968",2002,"Antifertility effects of methylmethane sulphonate on male reproductive organs of wild Indian house rat: histological and histochemical characteristics.","12463968","Methyl Methanesulfonate","Sertoli Cells",1,1,1]
["Methyl Methanesulfonate","Sperm Count",0,1,"12463968",2002,"Antifertility effects of methylmethane sulphonate on male reproductive organs of wild Indian house rat: histological and histochemical characteristics.","12463968","Methyl Methanesulfonate","Sperm Count",1,1,1]
["Methyl Methanesulfonate","Sperm Count",1,1,"15928457",2005,"A time-course characterization of male reproductive toxicity in rats treated with methyl methanesulphonate (MMS).","15928457","Methyl Methanesulfonate","Sperm Count",1,1,1]
["Methyl Methanesulfonate","Sperm Count",1,1,"16034192",2005,"Evaluation of testicular toxicity and sperm morphology in rats treated with methyl methanesulphonate (MMS).","16034192","Methyl Methanesulfonate","Sperm Count",1,1,1]
["Methyl Methanesulfonate","Sperm Count",1,1,"6882214",1983,"Evaluation of a testicular sperm head counting technique using rats exposed to dimethoxyethyl phthalate (DMEP), glycerol alpha-monochlorohydrin (GMCH), epichlorohydrin (ECH), formaldehyde (FA), or methyl methanesulphonate (MMS).","6882214","Methyl Methanesulfonate","Sperm Count",1,1,1]
["Methyl Methanesulfonate","Sperm Count",1,1,"9057879",1997,"The activity of ENU, iPMS and MMS in male mouse germ cells using the Muta Mouse positive selection transgenic mutation assay.","9057879","Methyl Methanesulfonate","Sperm Count",1,1,1]
["Methyl Methanesulfonate","Sperm Head",1,1,"16034192",2005,"Evaluation of testicular toxicity and sperm morphology in rats treated with methyl methanesulphonate (MMS).","16034192","Methyl Methanesulfonate","Sperm Head",1,1,1]
["Methyl Methanesulfonate","Sperm Head",1,1,"6882214",1983,"Evaluation of a testicular sperm head counting technique using rats exposed to dimethoxyethyl phthalate (DMEP), glycerol alpha-monochlorohydrin (GMCH), epichlorohydrin (ECH), formaldehyde (FA), or methyl methanesulphonate (MMS).","6882214","Methyl Methanesulfonate","Sperm Head",1,1,1]
["Methyl Methanesulfonate","Sperm Head",0,1,"7460068",1981,"A comparison of the molecular action of an SN1-type methylating agent, methyl nitrosourea and an SN2-type methylating agent, methyl methanesulfonate, in the germ cells of male mice.","7460068","Methyl Methanesulfonate","Sperm Head",1,1,1]
["Methyl Methanesulfonate","Sperm Head",1,1,"8444143",1993,"Effects of methyl methanesulfonate on mouse sperm chromatin structure and testicular cell kinetics.","8444143","Methyl Methanesulfonate","Sperm Head",1,1,1]
["Methyl Methanesulfonate","Sperm Motility",1,1,"15928457",2005,"A time-course characterization of male reproductive toxicity in rats treated with methyl methanesulphonate (MMS).","15928457","Methyl Methanesulfonate","Sperm Motility",1,1,1]
["Methyl Methanesulfonate","Spermatids",0,1,"12463968",2002,"Antifertility effects of methylmethane sulphonate on male reproductive organs of wild Indian house rat: histological and histochemical characteristics.","12463968","Methyl Methanesulfonate","Spermatids",1,1,1]
["Methyl Methanesulfonate","Spermatids",0,1,"181674",1976,"Studies on DNA repair in early spermatid stages of male mice after in vivo treatment with methyl-, ethyl-, propyl-, and isopropyl methanesulfonate.","181674","Methyl Methanesulfonate","Spermatids",1,1,1]
["Methyl Methanesulfonate","Spermatids",0,1,"206828",1978,"Unscheduled DNA synthesis induced in mouse spermatids after combined treatment with methyl methanesulfonate and X-rays.","206828","Methyl Methanesulfonate","Spermatids",1,1,1]
["Methyl Methanesulfonate","Spermatids",0,1,"3569170",1987,"Effect of mode of administration of methyl methanesulfonate and triethylenemelamine on induction of unscheduled DNA synthesis in mouse germ cells.","3569170","Methyl Methanesulfonate","Spermatids",1,1,1]
["Methyl Methanesulfonate","Spermatids",0,1,"6682172",1983,"Caffeine pretreatment enhances the unscheduled DNA synthesis in spermatids of mice exposed to methyl methanesulfonate.","6682172","Methyl Methanesulfonate","Spermatids",1,1,1]
["Methyl Methanesulfonate","Spermatids",0,1,"7326994",1981,"Formation of chromosome-type aberrations at the first cleavage after MMS treatment in late spermatids of mice.","7326994","Methyl Methanesulfonate","Spermatids",1,1,1]
["Methyl Methanesulfonate","Spermatogenesis",1,1,"11349439",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 15). Two-week and 4-week administration study of methyl methanesulfonate (MMS).","11349439","Methyl Methanesulfonate","Spermatogenesis",1,1,1]
["Methyl Methanesulfonate","Spermatogenesis",0,1,"12463968",2002,"Antifertility effects of methylmethane sulphonate on male reproductive organs of wild Indian house rat: histological and histochemical characteristics.","12463968","Methyl Methanesulfonate","Spermatogenesis",1,1,1]
["Methyl Methanesulfonate","Spermatogenesis",1,1,"16034192",2005,"Evaluation of testicular toxicity and sperm morphology in rats treated with methyl methanesulphonate (MMS).","16034192","Methyl Methanesulfonate","Spermatogenesis",1,1,1]
["Methyl Methanesulfonate","Spermatogenesis",0,1,"189187",1977,"Heritable translocation test and dominant-lethal assay in mice with methyl methanesulfonate.","189187","Methyl Methanesulfonate","Spermatogenesis",1,1,1]
["Methyl Methanesulfonate","Spermatogenesis",1,1,"2342498",1990,"Induction of specific-locus and dominant lethal mutations in male mice in the low dose range by methyl methanesulfonate (MMS).","2342498","Methyl Methanesulfonate","Spermatogenesis",1,1,1]
["Methyl Methanesulfonate","Spermatogenesis",0,1,"3753620",1986,"The use of alkaline elution procedures to measure DNA damage in spermiogenic stages of mice exposed to methyl methanesulfonate.","3753620","Methyl Methanesulfonate","Spermatogenesis",1,1,1]
["Methyl Methanesulfonate","Spermatogenesis",1,1,"6420234",1983,"[Effect of methylmethane sulfonate-sensitive mutations on nondisjunction and loss of sex chromosomes in Drosophila males].","6420234","Methyl Methanesulfonate","Spermatogenesis",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3780,I3780)","v":"Methyl Methanesulfonate"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3780,J3780)","v":"Spermatozoa"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3780,H3780)","v":"12463968"},2002,"Antifertility effects of methylmethane sulphonate on male reproductive organs of wild Indian house rat: histological and histochemical characteristics.","12463968","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"15928457",2005,"A time-course characterization of male reproductive toxicity in rats treated with methyl methanesulphonate (MMS).","15928457","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"16034192",2005,"Evaluation of testicular toxicity and sperm morphology in rats treated with methyl methanesulphonate (MMS).","16034192","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"1628810",1992,"Molecular analysis of mutations induced in the vermilion gene of Drosophila melanogaster by methyl methanesulfonate.","1628810","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"166020",1975,"Complementation analysis of methyl methane-sulfonate-induced recessive lethal mutations in the zeste-white region of the X chromosome of Drosophila melanogaster.","166020","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"171565",1975,"Cytogenetic analysis of meiotic chromosomes of irradiated mice and their progeny after treatment with streptomycin and dihydrodeoxystreptomycin.","171565","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"175269",1975,"Studies on chemically induced dominant lethality. I. The cytogenetic basis of MMS-induced dominant lethality in post-meiotic male germ cells.","175269","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"17675332",2007,"ReProComet: a new in vitro method to assess DNA damage in mammalian sperm.","17675332","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"181674",1976,"Studies on DNA repair in early spermatid stages of male mice after in vivo treatment with methyl-, ethyl-, propyl-, and isopropyl methanesulfonate.","181674","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"1824000",1991,"Inhibition of methyl methanesulfonate-induced unscheduled DNA synthesis in spermatozoa of mice by Poly I-C.","1824000","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"189187",1977,"Heritable translocation test and dominant-lethal assay in mice with methyl methanesulfonate.","189187","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"205193",1978,"DNA repair processes in germ cells demonstrated in ejaculated sperms of rabbits treated with methyl methane sulfonate.","205193","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"206828",1978,"Unscheduled DNA synthesis induced in mouse spermatids after combined treatment with methyl methanesulfonate and X-rays.","206828","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"209323",1978,"Embryopathies due to spermatozoal impairment in Xenopus laevis.","209323","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"223527",1979,"Unscheduled DNA synthesis in male rabbit germ cells induced by methylmethane sulfonate, cyclophosphamide and adriamycin.","223527","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"2342498",1990,"Induction of specific-locus and dominant lethal mutations in male mice in the low dose range by methyl methanesulfonate (MMS).","2342498","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"23744483",2013,"Parental exposure to methyl methane sulfonate of three-spined stickleback: contribution of DNA damage in male and female germ cells to further development impairment in progeny.","23744483","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"2494441",1989,"Dosage-response relationships for methyl methanesulfonate in Drosophila melanogaster spermatozoa: DNA methylation per nucleotide vs. sex-linked recessive lethal frequency.","2494441","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"2797023",1989,"Mechanism of chromosome aberration induction in the mouse egg fertilized with sperm recovered from postmeiotic germ cells treated with methyl methanesulfonate.","2797023","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"3352623",1988,"Chromosomal analysis in mouse eggs fertilized in vitro with sperm exposed to ultraviolet light (UV) and methyl and ethyl methanesulfonate (MMS and EMS).","3352623","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"3753620",1986,"The use of alkaline elution procedures to measure DNA damage in spermiogenic stages of mice exposed to methyl methanesulfonate.","3753620","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"6415474",1983,"Effect of storage and dose on MMS-induced deletions. Complementation analysis of X-chromosomal recessive lethals in the zeste-white and maroon-like regions of Drosophila melanogaster.","6415474","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"6422282",1984,"Dominant lethal mutations induced by MMS and mitomycin C in the fish Oryzias latipes.","6422282","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"6633552",1983,"Methylation of DNA and protamine by methyl methanesulfonate in the germ cells of male mice.","6633552","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"6882214",1983,"Evaluation of a testicular sperm head counting technique using rats exposed to dimethoxyethyl phthalate (DMEP), glycerol alpha-monochlorohydrin (GMCH), epichlorohydrin (ECH), formaldehyde (FA), or methyl methanesulphonate (MMS).","6882214","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"7121503",1982,"The use of fertilised mouse eggs in detecting potential clastogens.","7121503","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"7326994",1981,"Formation of chromosome-type aberrations at the first cleavage after MMS treatment in late spermatids of mice.","7326994","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"7460068",1981,"A comparison of the molecular action of an SN1-type methylating agent, methyl nitrosourea and an SN2-type methylating agent, methyl methanesulfonate, in the germ cells of male mice.","7460068","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",0,1,"7687010",1993,"Effects of treatment with methyl methanesulfonate during meiotic and postmeiotic stages and maturation of spermatozoa in mice.","7687010","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"7721062",1995,"[Maternal effect of the mutagen-sensitive mutation mus(2)201G1 on mutagenesis in Drosophila melanogaster spermatozoid genome, induced by ethylene imine and methylmethane sulfonate].","7721062","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"8444143",1993,"Effects of methyl methanesulfonate on mouse sperm chromatin structure and testicular cell kinetics.","8444143","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057872",1997,"Preliminary results of ethylnitrosourea, isopropyl methanesulphonate and methyl methanesulphonate activity in the testis and epididymal spermatozoa of Muta Mice.","9057872","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057873",1997,"Evaluation of the transgenic Lambda/LacI mouse model as a short-term predictor of heritable risk.","9057873","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057875",1997,"Effect of ethylnitrosourea and methyl methanesulfonate on mutation frequency in Muta Mouse germ cells (seminiferous tubule cells and epididymis spermatozoa).","9057875","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057876",1997,"Ethyl nitrosourea and methyl methanesulfonate mutagenicity in sperm and testicular germ cells of lacZ transgenic mice (Muta Mouse).","9057876","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057877",1997,"Germ-cell mutagenesis in lambda lacZ transgenic mice treated with ethylating and methylating agents: comparison with specific-locus test.","9057877","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057878",1997,"Analysis of the mutagenic potential of ENU and MMS in germ cells of male C57BL/6 lacI transgenic mice.","9057878","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057879",1997,"The activity of ENU, iPMS and MMS in male mouse germ cells using the Muta Mouse positive selection transgenic mutation assay.","9057879","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057880",1997,"Evaluation of lacI mutation in germ cells and micronuclei in peripheral blood after treatment of male lacI transgenic mice with ethylnitrosourea, isopropylmethane sulfonate or methylmethane sulfonate.","9057880","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057881",1997,"Toward an understanding of the use of transgenic mice for the detection of gene mutations in germ cells.","9057881","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057883",1997,"The detection of gene mutation in the tubular sperm of Muta Mice following a single intraperitoneal treatment with methyl methanesulphonate or ethylnitrosourea.","9057883","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Spermatozoa",1,1,"9057884",1997,"Germ cell mutagenesis in lacZ transgenic mice treated with methyl methanesulfonate.","9057884","Methyl Methanesulfonate","Spermatozoa",1,1,1]
["Methyl Methanesulfonate","Testis",1,1,"11349439",2000,"Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 15). Two-week and 4-week administration study of methyl methanesulfonate (MMS).","11349439","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Testis",0,1,"12463968",2002,"Antifertility effects of methylmethane sulphonate on male reproductive organs of wild Indian house rat: histological and histochemical characteristics.","12463968","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Testis",1,1,"16034192",2005,"Evaluation of testicular toxicity and sperm morphology in rats treated with methyl methanesulphonate (MMS).","16034192","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Testis",0,1,"181674",1976,"Studies on DNA repair in early spermatid stages of male mice after in vivo treatment with methyl-, ethyl-, propyl-, and isopropyl methanesulfonate.","181674","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Testis",0,1,"3569170",1987,"Effect of mode of administration of methyl methanesulfonate and triethylenemelamine on induction of unscheduled DNA synthesis in mouse germ cells.","3569170","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Testis",1,1,"6882214",1983,"Evaluation of a testicular sperm head counting technique using rats exposed to dimethoxyethyl phthalate (DMEP), glycerol alpha-monochlorohydrin (GMCH), epichlorohydrin (ECH), formaldehyde (FA), or methyl methanesulphonate (MMS).","6882214","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Testis",1,1,"8444143",1993,"Effects of methyl methanesulfonate on mouse sperm chromatin structure and testicular cell kinetics.","8444143","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Testis",1,1,"9057872",1997,"Preliminary results of ethylnitrosourea, isopropyl methanesulphonate and methyl methanesulphonate activity in the testis and epididymal spermatozoa of Muta Mice.","9057872","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Testis",1,1,"9057876",1997,"Ethyl nitrosourea and methyl methanesulfonate mutagenicity in sperm and testicular germ cells of lacZ transgenic mice (Muta Mouse).","9057876","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Testis",1,1,"9057879",1997,"The activity of ENU, iPMS and MMS in male mouse germ cells using the Muta Mouse positive selection transgenic mutation assay.","9057879","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Testis",1,1,"9057884",1997,"Germ cell mutagenesis in lacZ transgenic mice treated with methyl methanesulfonate.","9057884","Methyl Methanesulfonate","Testis",1,1,1]
["Methyl Methanesulfonate","Vas Deferens",1,1,"9057877",1997,"Germ-cell mutagenesis in lambda lacZ transgenic mice treated with ethylating and methylating agents: comparison with specific-locus test.","9057877","Methyl Methanesulfonate","Vas Deferens",1,1,1]
["Methyl Parathion","Epididymis",1,1,"17171610",2006,"The reproductive toxicity of the organophosphate pesticide 0, 0-dimethyl 0-4-nitrophenyl phosphorothioate (methyl parathion) in the male rat.","17171610","Methyl Parathion","Epididymis",1,null,1]
["Methyl Parathion","Genitalia, Male",1,1,"16783732",2006,"Neonatal methyl parathion exposure affects the growth and functions of the male reproductive system in the adult rat.","16783732","Methyl Parathion","Genitalia, Male",1,null,1]
["Methyl Parathion","Prostate",1,1,"17171610",2006,"The reproductive toxicity of the organophosphate pesticide 0, 0-dimethyl 0-4-nitrophenyl phosphorothioate (methyl parathion) in the male rat.","17171610","Methyl Parathion","Prostate",1,null,1]
["Methyl Parathion","Seminal Vesicles",1,1,"17171610",2006,"The reproductive toxicity of the organophosphate pesticide 0, 0-dimethyl 0-4-nitrophenyl phosphorothioate (methyl parathion) in the male rat.","17171610","Methyl Parathion","Seminal Vesicles",1,null,1]
["Methyl Parathion","Sperm Count",1,1,"16226487",2005,"Effects of methyl parathion (o,o-dimethyl o-4-nitrophenyl phosphorothioate) on rat sperm morphology and sperm count, but not fertility, are associated with decreased ascorbic acid level in the testis.","16226487","Methyl Parathion","Sperm Count",1,null,1]
["Methyl Parathion","Sperm Count",1,1,"16783732",2006,"Neonatal methyl parathion exposure affects the growth and functions of the male reproductive system in the adult rat.","16783732","Methyl Parathion","Sperm Count",1,null,1]
["Methyl Parathion","Sperm Motility",1,1,"19442678",2009,"Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa.","19442678","Methyl Parathion","Sperm Motility",1,null,1]
["Methyl Parathion","Spermatids",1,1,"16960428",2006,"An organophosphate insecticide methyl parathion (o- o- dimethyl o-4-nitrophenyl phosphorothioate) induces cytotoxic damage and tubular atrophy in the testis despite elevated testosterone level in the rat.","16960428","Methyl Parathion","Spermatids",1,null,1]
["Methyl Parathion","Spermatids",1,1,"18024115",2007,"Methyl parathion induces the formation of symplasts by round spermatid fusion and alters the biochemical parameters in the testis.","18024115","Methyl Parathion","Spermatids",1,null,1]
["Methyl Parathion","Spermatocytes",1,1,"1021406",1976,"[Morphologic changes in the testes of white rats chronically subjected to vofatox 50].","1021406","Methyl Parathion","Spermatocytes",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3844,I3844)","v":"Methyl Parathion"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3844,J3844)","v":"Spermatogenesis"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3844,H3844)","v":"16784764"},2006,"Genetic damage caused by methyl-parathion in mouse spermatozoa is related to oxidative stress.","16784764","Methyl Parathion","Spermatogenesis",1,null,1]
["Methyl Parathion","Spermatogenesis",1,1,"19442678",2009,"Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa.","19442678","Methyl Parathion","Spermatogenesis",1,null,1]
["Methyl Parathion","Spermatogonia",1,1,"6464028",1984,"Absence of genetic and cytogenetic effects in mice treated by the organophosphorus insecticide parathion, its methyl analogue, and paraoxon.","6464028","Methyl Parathion","Spermatogonia",1,null,1]
["Methyl Parathion","Spermatozoa",1,1,"1381479",1992,"Methyl parathion-induced sperm shape abnormalities in mouse.","1381479","Methyl Parathion","Spermatozoa",1,null,1]
["Methyl Parathion","Spermatozoa",1,1,"16226487",2005,"Effects of methyl parathion (o,o-dimethyl o-4-nitrophenyl phosphorothioate) on rat sperm morphology and sperm count, but not fertility, are associated with decreased ascorbic acid level in the testis.","16226487","Methyl Parathion","Spermatozoa",1,null,1]
["Methyl Parathion","Spermatozoa",1,1,"16783732",2006,"Neonatal methyl parathion exposure affects the growth and functions of the male reproductive system in the adult rat.","16783732","Methyl Parathion","Spermatozoa",1,null,1]
["Methyl Parathion","Spermatozoa",1,1,"16784764",2006,"Genetic damage caused by methyl-parathion in mouse spermatozoa is related to oxidative stress.","16784764","Methyl Parathion","Spermatozoa",1,null,1]
["Methyl Parathion","Spermatozoa",1,1,"19442678",2009,"Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa.","19442678","Methyl Parathion","Spermatozoa",1,null,1]
["Methyl Parathion","Testis",1,1,"1021406",1976,"[Morphologic changes in the testes of white rats chronically subjected to vofatox 50].","1021406","Methyl Parathion","Testis",1,null,1]
["Methyl Parathion","Testis",1,1,"16226487",2005,"Effects of methyl parathion (o,o-dimethyl o-4-nitrophenyl phosphorothioate) on rat sperm morphology and sperm count, but not fertility, are associated with decreased ascorbic acid level in the testis.","16226487","Methyl Parathion","Testis",1,null,1]
["Methyl Parathion","Testis",1,1,"16783732",2006,"Neonatal methyl parathion exposure affects the growth and functions of the male reproductive system in the adult rat.","16783732","Methyl Parathion","Testis",1,null,1]
["Methyl Parathion","Testis",1,1,"16960428",2006,"An organophosphate insecticide methyl parathion (o- o- dimethyl o-4-nitrophenyl phosphorothioate) induces cytotoxic damage and tubular atrophy in the testis despite elevated testosterone level in the rat.","16960428","Methyl Parathion","Testis",1,null,1]
["Methyl Parathion","Testis",1,1,"18024115",2007,"Methyl parathion induces the formation of symplasts by round spermatid fusion and alters the biochemical parameters in the testis.","18024115","Methyl Parathion","Testis",1,null,1]
["Methyl Parathion","Vas Deferens",1,1,"17171610",2006,"The reproductive toxicity of the organophosphate pesticide 0, 0-dimethyl 0-4-nitrophenyl phosphorothioate (methyl parathion) in the male rat.","17171610","Methyl Parathion","Vas Deferens",1,null,1]
["molinate","Leydig Cells",1,1,"9705884",1998,"The reproductive toxicity of molinate and metabolites to the male rat: effects on testosterone and sperm morphology.","9705884","molinate","Leydig Cells",1,1,1]
["molinate","Seminiferous Tubules",1,1,"9571984",1998,"Testicular toxicity of molinate in the rat: metabolic activation via sulfoxidation.","9571984","molinate","Seminiferous Tubules",1,1,1]
["molinate","Seminiferous Tubules",1,1,"9705884",1998,"The reproductive toxicity of molinate and metabolites to the male rat: effects on testosterone and sperm morphology.","9705884","molinate","Seminiferous Tubules",1,1,1]
["molinate","Sertoli Cells",1,1,"9571984",1998,"Testicular toxicity of molinate in the rat: metabolic activation via sulfoxidation.","9571984","molinate","Sertoli Cells",1,1,1]
["molinate","Spermatids",1,1,"9571984",1998,"Testicular toxicity of molinate in the rat: metabolic activation via sulfoxidation.","9571984","molinate","Spermatids",1,1,1]
["molinate","Spermatids",1,1,"9705884",1998,"The reproductive toxicity of molinate and metabolites to the male rat: effects on testosterone and sperm morphology.","9705884","molinate","Spermatids",1,1,1]
["molinate","Spermatogenesis",0,1,"16417035",2005,"Mode of action: reduction of testosterone availability--molinate-induced inhibition of spermatogenesis.","16417035","molinate","Spermatogenesis",1,1,1]
["molinate","Spermatogenesis",1,1,"9571984",1998,"Testicular toxicity of molinate in the rat: metabolic activation via sulfoxidation.","9571984","molinate","Spermatogenesis",1,1,1]
["molinate","Spermatozoa",1,1,"10689202",2000,"In vitro fertilization after in vivo treatment of rats with three reproductive toxicants.","10689202","molinate","Spermatozoa",1,1,1]
["molinate","Spermatozoa",1,1,"9705884",1998,"The reproductive toxicity of molinate and metabolites to the male rat: effects on testosterone and sperm morphology.","9705884","molinate","Spermatozoa",1,1,1]
["molinate","Testis",1,1,"9571984",1998,"Testicular toxicity of molinate in the rat: metabolic activation via sulfoxidation.","9571984","molinate","Testis",1,1,1]
["molinate","Testis",1,1,"9705884",1998,"The reproductive toxicity of molinate and metabolites to the male rat: effects on testosterone and sperm morphology.","9705884","molinate","Testis",1,1,1]
["N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide","Testis",1,1,"17659344",2007,"Evaluation of neurodevelopmental effects on rats exposed prenatally to sulfentrazone.","17659344","N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl)phenyl)methanesulfonamide","Testis",1,null,1]
["n-butoxyethanol","Sperm Motility",1,1,"2086313",1990,"Assessment of ethylene glycol monobutyl and monophenyl ether reproductive toxicity using a continuous breeding protocol in Swiss CD-1 mice.","2086313","n-butoxyethanol","Sperm Motility",1,null,1]
["n-butoxyethanol","Spermatozoa",1,1,"2086313",1990,"Assessment of ethylene glycol monobutyl and monophenyl ether reproductive toxicity using a continuous breeding protocol in Swiss CD-1 mice.","2086313","n-butoxyethanol","Spermatozoa",1,null,1]
["n-butoxyethanol","Testis",1,1,"9114293",1997,"Reproductive toxicology. Ethylene glycol monobutyl ether.","9114293","n-butoxyethanol","Testis",1,null,1]
["nitrobenzene","Epididymis",1,1,"7595970",1995,"Studies on the establishment of appropriate spermatogenic endpoints for male fertility disturbance in rodent induced by drugs and chemicals. I. Nitrobenzene.","7595970","nitrobenzene","Epididymis",1,null,1]
["nitrobenzene","Epididymis",1,1,"9442449",1997,"A flow cytometric analysis of cytotoxic effects of nitrobenzene on rat spermatogenesis.","9442449","nitrobenzene","Epididymis",1,null,1]
["nitrobenzene","Seminiferous Tubules",1,1,"3212784",1988,"The reversibility of nitrobenzene-induced testicular toxicity: continuous monitoring of sperm output from vasocystotomized rats.","3212784","nitrobenzene","Seminiferous Tubules",1,null,1]
["nitrobenzene","Seminiferous Tubules",1,1,"8258392",1993,"Identification of stage-specific changes in protein secretion by isolated seminiferous tubules from the rat following exposure to either m-dinitrobenzene or nitrobenzene.","8258392","nitrobenzene","Seminiferous Tubules",1,null,1]
["nitrobenzene","Sertoli Cells",1,1,"12595153",2003,"Fas- or FasL-deficient mice display an increased sensitivity to nitrobenzene-induced testicular germ cell apoptosis.","12595153","nitrobenzene","Sertoli Cells",1,null,1]
["nitrobenzene","Sperm Count",1,1,"3212784",1988,"The reversibility of nitrobenzene-induced testicular toxicity: continuous monitoring of sperm output from vasocystotomized rats.","3212784","nitrobenzene","Sperm Count",1,null,1]
["nitrobenzene","Sperm Count",1,1,"7595970",1995,"Studies on the establishment of appropriate spermatogenic endpoints for male fertility disturbance in rodent induced by drugs and chemicals. I. Nitrobenzene.","7595970","nitrobenzene","Sperm Count",1,null,1]
["nitrobenzene","Sperm Motility",1,1,"7595970",1995,"Studies on the establishment of appropriate spermatogenic endpoints for male fertility disturbance in rodent induced by drugs and chemicals. I. Nitrobenzene.","7595970","nitrobenzene","Sperm Motility",1,null,1]
["nitrobenzene","Spermatids",1,1,"3609536",1987,"Reproduction and fertility evaluations in CD rats following nitrobenzene inhalation.","3609536","nitrobenzene","Spermatids",1,null,1]
["nitrobenzene","Spermatocytes",1,1,"3609536",1987,"Reproduction and fertility evaluations in CD rats following nitrobenzene inhalation.","3609536","nitrobenzene","Spermatocytes",1,null,1]
["nitrobenzene","Spermatocytes",1,1,"9442449",1997,"A flow cytometric analysis of cytotoxic effects of nitrobenzene on rat spermatogenesis.","9442449","nitrobenzene","Spermatocytes",1,null,1]
["nitrobenzene","Spermatocytes",1,1,"9630016",1998,"Involvement of apoptosis in the rat germ cell degeneration induced by nitrobenzene.","9630016","nitrobenzene","Spermatocytes",1,null,1]
["nitrobenzene","Spermatogenesis",1,1,"3212784",1988,"The reversibility of nitrobenzene-induced testicular toxicity: continuous monitoring of sperm output from vasocystotomized rats.","3212784","nitrobenzene","Spermatogenesis",1,null,1]
["nitrobenzene","Spermatogenesis",1,1,"7595970",1995,"Studies on the establishment of appropriate spermatogenic endpoints for male fertility disturbance in rodent induced by drugs and chemicals. I. Nitrobenzene.","7595970","nitrobenzene","Spermatogenesis",1,null,1]
["nitrobenzene","Spermatogenesis",1,1,"8258392",1993,"Identification of stage-specific changes in protein secretion by isolated seminiferous tubules from the rat following exposure to either m-dinitrobenzene or nitrobenzene.","8258392","nitrobenzene","Spermatogenesis",1,null,1]
["nitrobenzene","Spermatogenesis",1,1,"9442449",1997,"A flow cytometric analysis of cytotoxic effects of nitrobenzene on rat spermatogenesis.","9442449","nitrobenzene","Spermatogenesis",1,null,1]
["nitrobenzene","Spermatozoa",1,1,"12595153",2003,"Fas- or FasL-deficient mice display an increased sensitivity to nitrobenzene-induced testicular germ cell apoptosis.","12595153","nitrobenzene","Spermatozoa",1,null,1]
["nitrobenzene","Spermatozoa",1,1,"20858646",2011,"Acute toxicity and mutagenesis of three metabolites mixture of nitrobenzene in mice.","20858646","nitrobenzene","Spermatozoa",1,null,1]
["nitrobenzene","Spermatozoa",1,1,"7595970",1995,"Studies on the establishment of appropriate spermatogenic endpoints for male fertility disturbance in rodent induced by drugs and chemicals. I. Nitrobenzene.","7595970","nitrobenzene","Spermatozoa",1,null,1]
["nitrobenzene","Testis",1,1,"12595153",2003,"Fas- or FasL-deficient mice display an increased sensitivity to nitrobenzene-induced testicular germ cell apoptosis.","12595153","nitrobenzene","Testis",1,null,1]
["nitrobenzene","Testis",1,1,"3609536",1987,"Reproduction and fertility evaluations in CD rats following nitrobenzene inhalation.","3609536","nitrobenzene","Testis",1,null,1]
["nitrobenzene","Testis",1,1,"7595970",1995,"Studies on the establishment of appropriate spermatogenic endpoints for male fertility disturbance in rodent induced by drugs and chemicals. I. Nitrobenzene.","7595970","nitrobenzene","Testis",1,null,1]
["nitrobenzene","Testis",1,1,"7966451",1994,"Confirmation study, using nitrobenzene, of the Combined Repeat Dose and Reproductive/Developmental Toxicity Test protocol proposed by the Organization for Economic Cooperation and Development (OECD).","7966451","nitrobenzene","Testis",1,null,1]
["nitrobenzene","Testis",1,1,"8258392",1993,"Identification of stage-specific changes in protein secretion by isolated seminiferous tubules from the rat following exposure to either m-dinitrobenzene or nitrobenzene.","8258392","nitrobenzene","Testis",1,null,1]
["nitrobenzene","Testis",1,1,"9442449",1997,"A flow cytometric analysis of cytotoxic effects of nitrobenzene on rat spermatogenesis.","9442449","nitrobenzene","Testis",1,null,1]
["nitrobenzene","Vas Deferens",1,1,"3212784",1988,"The reversibility of nitrobenzene-induced testicular toxicity: continuous monitoring of sperm output from vasocystotomized rats.","3212784","nitrobenzene","Vas Deferens",1,null,1]
["Nitrofurazone","Epididymis",1,1,"9114349",1997,"Reproductive toxicology. Nitrofurazone.","9114349","Nitrofurazone","Epididymis",1,1,1]
["Nitrofurazone","Genitalia, Male",0,1,"11250792",2001,"Effect of nitrofurazone on the reproductive organs in adult male mice.","11250792","Nitrofurazone","Genitalia, Male",1,1,1]
["Nitrofurazone","Leydig Cells",0,1,"646141",1978,"The effect of nitrofurazone on the endocrine, secretory and spermatogenic functions of the rat testis.","646141","Nitrofurazone","Leydig Cells",1,1,1]
["Nitrofurazone","Sertoli Cells",0,1,"646141",1978,"The effect of nitrofurazone on the endocrine, secretory and spermatogenic functions of the rat testis.","646141","Nitrofurazone","Sertoli Cells",1,1,1]
["Nitrofurazone","Sperm Count",0,1,"3315570",1987,"[The effect of nitrofurazone on the state of sperm in the stallion].","3315570","Nitrofurazone","Sperm Count",1,1,1]
["Nitrofurazone","Sperm Count",1,1,"8667458",1995,"Effects of nitrofurazone on spermatogenesis and reproductive toxicity in male rats--part of a collaborative work to determine optimal administration period and endpoints.","8667458","Nitrofurazone","Sperm Count",1,1,1]
["Nitrofurazone","Sperm Count",1,1,"9114349",1997,"Reproductive toxicology. Nitrofurazone.","9114349","Nitrofurazone","Sperm Count",1,1,1]
["Nitrofurazone","Sperm Head",1,1,"8667458",1995,"Effects of nitrofurazone on spermatogenesis and reproductive toxicity in male rats--part of a collaborative work to determine optimal administration period and endpoints.","8667458","Nitrofurazone","Sperm Head",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3908,I3908)","v":"Nitrofurazone"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3908,J3908)","v":"Sperm Motility"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3908,H3908)","v":"1132530"},1975,"The nitrofurans as sperm-immobilizing agents, their tissue toxicity, and their clinical application in vasectomy.","1132530","Nitrofurazone","Sperm Motility",1,1,1]
["Nitrofurazone","Sperm Motility",0,1,"3315570",1987,"[The effect of nitrofurazone on the state of sperm in the stallion].","3315570","Nitrofurazone","Sperm Motility",1,1,1]
["Nitrofurazone","Spermatogenesis",0,1,"11250792",2001,"Effect of nitrofurazone on the reproductive organs in adult male mice.","11250792","Nitrofurazone","Spermatogenesis",1,1,1]
["Nitrofurazone","Spermatogenesis",1,1,"5110972",1971,"[Effect of testicular phosphatides on rat's testis damaged by furacin].","5110972","Nitrofurazone","Spermatogenesis",1,1,1]
["Nitrofurazone","Spermatogenesis",0,1,"646141",1978,"The effect of nitrofurazone on the endocrine, secretory and spermatogenic functions of the rat testis.","646141","Nitrofurazone","Spermatogenesis",1,1,1]
["Nitrofurazone","Spermatogenesis",1,1,"8667458",1995,"Effects of nitrofurazone on spermatogenesis and reproductive toxicity in male rats--part of a collaborative work to determine optimal administration period and endpoints.","8667458","Nitrofurazone","Spermatogenesis",1,1,1]
["Nitrofurazone","Spermatozoa",1,1,"1132530",1975,"The nitrofurans as sperm-immobilizing agents, their tissue toxicity, and their clinical application in vasectomy.","1132530","Nitrofurazone","Spermatozoa",1,1,1]
["Nitrofurazone","Spermatozoa",0,1,"3315570",1987,"[The effect of nitrofurazone on the state of sperm in the stallion].","3315570","Nitrofurazone","Spermatozoa",1,1,1]
["Nitrofurazone","Spermatozoa",1,1,"4422771",1974,"Nitrofurans: sperm-immobilizing agents. Their tissue toxicity and clinical application.","4422771","Nitrofurazone","Spermatozoa",1,1,1]
["Nitrofurazone","Spermatozoa",0,1,"5973165",1966,"Effect of nitrofurazone on the incorporation of L-lysine-U-14C into protein of rat testis.","5973165","Nitrofurazone","Spermatozoa",1,1,1]
["Nitrofurazone","Spermatozoa",0,1,"646141",1978,"The effect of nitrofurazone on the endocrine, secretory and spermatogenic functions of the rat testis.","646141","Nitrofurazone","Spermatozoa",1,1,1]
["Nitrofurazone","Spermatozoa",0,1,"648647",1978,"Nitrofurazone: vas irrigation as an adjunct in vasectomy.","648647","Nitrofurazone","Spermatozoa",1,1,1]
["Nitrofurazone","Spermatozoa",1,1,"9114349",1997,"Reproductive toxicology. Nitrofurazone.","9114349","Nitrofurazone","Spermatozoa",1,1,1]
["Nitrofurazone","Testis",1,1,"5110972",1971,"[Effect of testicular phosphatides on rat's testis damaged by furacin].","5110972","Nitrofurazone","Testis",1,1,1]
["Nitrofurazone","Testis",0,1,"5973165",1966,"Effect of nitrofurazone on the incorporation of L-lysine-U-14C into protein of rat testis.","5973165","Nitrofurazone","Testis",1,1,1]
["Nitrofurazone","Testis",0,1,"646141",1978,"The effect of nitrofurazone on the endocrine, secretory and spermatogenic functions of the rat testis.","646141","Nitrofurazone","Testis",1,1,1]
["Nitrofurazone","Testis",1,1,"8667458",1995,"Effects of nitrofurazone on spermatogenesis and reproductive toxicity in male rats--part of a collaborative work to determine optimal administration period and endpoints.","8667458","Nitrofurazone","Testis",1,1,1]
["Nitrofurazone","Testis",1,1,"9114349",1997,"Reproductive toxicology. Nitrofurazone.","9114349","Nitrofurazone","Testis",1,1,1]
["Nitrofurazone","Urogenital Abnormalities",0,1,"4886585",1967,"[Etiological, diagnostic and therapeutic considerations on infections of the infantile urinary tract].","4886585","Nitrofurazone","Urogenital Abnormalities",1,1,1]
["Nitrofurazone","Vas Deferens",1,1,"1132530",1975,"The nitrofurans as sperm-immobilizing agents, their tissue toxicity, and their clinical application in vasectomy.","1132530","Nitrofurazone","Vas Deferens",1,1,1]
["Nitrofurazone","Vas Deferens",1,1,"4422771",1974,"Nitrofurans: sperm-immobilizing agents. Their tissue toxicity and clinical application.","4422771","Nitrofurazone","Vas Deferens",1,1,1]
["Nitrofurazone","Vas Deferens",0,1,"648647",1978,"Nitrofurazone: vas irrigation as an adjunct in vasectomy.","648647","Nitrofurazone","Vas Deferens",1,1,1]
["paclobutrazol","Spermatogenesis",1,1,"22789407",2012,"Exposure to paclobutrazol disrupts spermatogenesis in male Sebastiscus marmoratus.","22789407","paclobutrazol","Spermatogenesis",1,null,1]
["paclobutrazol","Testis",1,1,"22789407",2012,"Exposure to paclobutrazol disrupts spermatogenesis in male Sebastiscus marmoratus.","22789407","paclobutrazol","Testis",1,null,1]
["Pentachlorophenol","Spermatozoa",1,1,"10354001",1999,"Toxicity of metals and pesticides using the sperm cell bioassay with the sea urchin Arbacia spatuligera.","10354001","Pentachlorophenol","Spermatozoa",1,1,1]
["Pentachlorophenol","Spermatozoa",1,1,"12781203",2003,"Flow cytometric assessment of changes in rat sperm mitochondrial function after treatment with pentachlorophenol.","12781203","Pentachlorophenol","Spermatozoa",1,1,1]
["Pentachlorophenol","Testis",1,1,"16620794",2006,"Effects of pentachlorophenol on the reproduction of Japanese medaka (Oryzias latipes).","16620794","Pentachlorophenol","Testis",1,1,1]
["Pentachlorophenol","Testis",1,1,"19082768",2008,"Developmental exposure to pentachlorophenol affects the expression of thyroid hormone receptor beta1 and synapsin I in brain, resulting in thyroid function vulnerability in rats.","19082768","Pentachlorophenol","Testis",1,1,1]
["Pentachlorophenol","Testis",1,1,"9713382",1998,"Reproductive effects in mink (Mustela vison) exposed to the pesticides Lindane, Carbofuran and Pentachlorophenol in a multigeneration study.","9713382","Pentachlorophenol","Testis",1,1,1]
["perfluorobutane","Testis",1,1,"17917760",2008,"Acute and chronic effects of perfluorobutane sulfonate (PFBS) on the mallard and northern bobwhite quail.","17917760","perfluorobutane","Testis",1,null,1]
["perfluorooctanoic acid","Leydig Cell Tumor",1,1,"15135214",2004,"Characterization of risk for general population exposure to perfluorooctanoate.","15135214","perfluorooctanoic acid","Leydig Cell Tumor",1,null,1]
["perfluorooctanoic acid","Sperm Count",1,1,"20223269",2010,"Male reproductive system parameters in a two-generation reproduction study of ammonium perfluorooctanoate in rats and human relevance.","20223269","perfluorooctanoic acid","Sperm Count",1,null,1]
["perfluorooctanoic acid","Sperm Count",1,1,"22647447",2012,"Exposure to perfluorinated compounds and human semen quality in Arctic and European populations.","22647447","perfluorooctanoic acid","Sperm Count",1,null,1]
["perfluorooctanoic acid","Sperm Count",0,1,"23360585",2013,"Associations of in utero exposure to perfluorinated alkyl acids with human semen quality and reproductive hormones in adult men.","23360585","perfluorooctanoic acid","Sperm Count",1,null,1]
["perfluorooctanoic acid","Sperm Motility",1,1,"19590671",2009,"Legacy for young men: PFAAs and human sperm.","19590671","perfluorooctanoic acid","Sperm Motility",1,null,1]
["perfluorooctanoic acid","Sperm Motility",1,1,"20223269",2010,"Male reproductive system parameters in a two-generation reproduction study of ammonium perfluorooctanoate in rats and human relevance.","20223269","perfluorooctanoic acid","Sperm Motility",1,null,1]
["perfluorooctanoic acid","Spermatozoa",1,1,"19590671",2009,"Legacy for young men: PFAAs and human sperm.","19590671","perfluorooctanoic acid","Spermatozoa",1,null,1]
["perfluorooctanoic acid","Spermatozoa",1,1,"19590684",2009,"Do perfluoroalkyl compounds impair human semen quality?","19590684","perfluorooctanoic acid","Spermatozoa",1,null,1]
["perfluorooctanoic acid","Spermatozoa",1,1,"20223269",2010,"Male reproductive system parameters in a two-generation reproduction study of ammonium perfluorooctanoate in rats and human relevance.","20223269","perfluorooctanoic acid","Spermatozoa",1,null,1]
["perfluorooctanoic acid","Spermatozoa",0,1,"23044208",2012,"Serum levels of perfluorinated compounds and sperm Y:X chromosome ratio in two European populations and in Inuit from Greenland.","23044208","perfluorooctanoic acid","Spermatozoa",1,null,1]
["perfluorooctanoic acid","Spermatozoa",0,1,"24889506",2014,"Exposure to perfluoroalkyl substances and sperm DNA global methylation in Arctic and European populations.","24889506","perfluorooctanoic acid","Spermatozoa",1,null,1]
["perfluorooctanoic acid","Testicular Neoplasms",1,1,"15135214",2004,"Characterization of risk for general population exposure to perfluorooctanoate.","15135214","perfluorooctanoic acid","Testicular Neoplasms",1,null,1]
["perfluorooctanoic acid","Testis",1,1,"20223269",2010,"Male reproductive system parameters in a two-generation reproduction study of ammonium perfluorooctanoate in rats and human relevance.","20223269","perfluorooctanoic acid","Testis",1,null,1]
["perfluorooctanoic acid","Testis",0,1,"23360585",2013,"Associations of in utero exposure to perfluorinated alkyl acids with human semen quality and reproductive hormones in adult men.","23360585","perfluorooctanoic acid","Testis",1,null,1]
["Phosmet","Sperm Count",1,1,"2555709",1989,"Effect of DNOC, Ferbam and Imidan exposure on mouse sperm morphology.","2555709","Phosmet","Sperm Count",1,null,1]
["Phosmet","Sperm Count",1,1,"3179769",1988,"[Morphologic changes in sperm in experimental mice after the administration of phosmet and mancozeb].","3179769","Phosmet","Sperm Count",1,null,1]
["Phosmet","Spermatozoa",1,1,"2555709",1989,"Effect of DNOC, Ferbam and Imidan exposure on mouse sperm morphology.","2555709","Phosmet","Spermatozoa",1,null,1]
["Phosmet","Spermatozoa",1,1,"3179769",1988,"[Morphologic changes in sperm in experimental mice after the administration of phosmet and mancozeb].","3179769","Phosmet","Spermatozoa",1,null,1]
["Phosmet","Testis",1,1,"2555709",1989,"Effect of DNOC, Ferbam and Imidan exposure on mouse sperm morphology.","2555709","Phosmet","Testis",1,null,1]
["Phosmet","Testis",1,1,"3179769",1988,"[Morphologic changes in sperm in experimental mice after the administration of phosmet and mancozeb].","3179769","Phosmet","Testis",1,null,1]
["procymidone","Genitalia, Male",1,1,"10188193",1999,"The fungicide procymidone alters sexual differentiation in the male rat by acting as an androgen-receptor antagonist in vivo and in vitro.","10188193","procymidone","Genitalia, Male",1,1,1]
["procymidone","Genitalia, Male",1,1,"20519838",2010,"Maternal exposure to procymidone has no effects on fetal external genitalia development in male rabbit fetuses in a modified developmental toxicity study.","20519838","procymidone","Genitalia, Male",1,1,1]
["procymidone","Leydig Cells",1,1,"16214947",2005,"Influence of long-term dietary administration of procymidone, a fungicide with anti-androgenic effects, or the phytoestrogen genistein to rats on the pituitary-gonadal axis and Leydig cell steroidogenesis.","16214947","procymidone","Leydig Cells",1,1,1]
["procymidone","Spermatogenesis",1,1,"16214947",2005,"Influence of long-term dietary administration of procymidone, a fungicide with anti-androgenic effects, or the phytoestrogen genistein to rats on the pituitary-gonadal axis and Leydig cell steroidogenesis.","16214947","procymidone","Spermatogenesis",1,1,1]
["procymidone","Spermatogenesis",1,1,"19303894",2009,"Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.","19303894","procymidone","Spermatogenesis",1,1,1]
["procymidone","Spermatozoa",1,1,"19303894",2009,"Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.","19303894","procymidone","Spermatozoa",1,1,1]
["procymidone","Testis",1,1,"16214947",2005,"Influence of long-term dietary administration of procymidone, a fungicide with anti-androgenic effects, or the phytoestrogen genistein to rats on the pituitary-gonadal axis and Leydig cell steroidogenesis.","16214947","procymidone","Testis",1,1,1]
["procymidone","Testis",1,1,"19303894",2009,"Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.","19303894","procymidone","Testis",1,1,1]
["Propylthiouracil","Cryptorchidism",0,1,"17033216",2006,"Effects of propylthiouracil on testicular tissue in undescended testes of newborn rats.","17033216","Propylthiouracil","Cryptorchidism",1,1,1]
["Propylthiouracil","Epididymis",0,1,"8294229",1993,"Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse.","8294229","Propylthiouracil","Epididymis",1,1,1]
["Propylthiouracil","Leydig Cells",0,1,"11861520",2002,"The goitrogen 6-n-propyl-2-thiouracil (PTU) given during testis development increases Sertoli and germ cell numbers per cyst in fish: the tilapia (Oreochromis niloticus) model.","11861520","Propylthiouracil","Leydig Cells",1,1,1]
["Propylthiouracil","Prostate",0,1,"4796897",1973,"Effect of propylthiouracil-induced hypothyroidism on serum levels of luteinizing hormone and follicle-stimulating hormone in the rat.","4796897","Propylthiouracil","Prostate",1,1,1]
["Propylthiouracil","Seminal Vesicles",0,1,"4796897",1973,"Effect of propylthiouracil-induced hypothyroidism on serum levels of luteinizing hormone and follicle-stimulating hormone in the rat.","4796897","Propylthiouracil","Seminal Vesicles",1,1,1]
["Propylthiouracil","Seminiferous Tubules",0,1,"11869372",2002,"Are germ cell factors essential in the testicular enlargement after neonatal hypothyroidism recovery? A study using W/Wv mutant mice model.","11869372","Propylthiouracil","Seminiferous Tubules",1,1,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I3972,I3972)","v":"Propylthiouracil"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J3972,J3972)","v":"Seminiferous Tubules"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H3972,H3972)","v":"18292836"},2007,"Comparative study of the effects of pre and post natal administration of a thyroid drug on testicular activity in adult rat.","18292836","Propylthiouracil","Seminiferous Tubules",1,1,1]
["Propylthiouracil","Sertoli Cells",0,1,"11861520",2002,"The goitrogen 6-n-propyl-2-thiouracil (PTU) given during testis development increases Sertoli and germ cell numbers per cyst in fish: the tilapia (Oreochromis niloticus) model.","11861520","Propylthiouracil","Sertoli Cells",1,1,1]
["Propylthiouracil","Sertoli Cells",0,1,"11869372",2002,"Are germ cell factors essential in the testicular enlargement after neonatal hypothyroidism recovery? A study using W/Wv mutant mice model.","11869372","Propylthiouracil","Sertoli Cells",1,1,1]
["Propylthiouracil","Sertoli Cells",0,1,"20525087",2010,"Postnatal testis development, Sertoli cell proliferation and number of different spermatogonial types in C57BL/6J mice made transiently hypo- and hyperthyroidic during the neonatal period.","20525087","Propylthiouracil","Sertoli Cells",1,1,1]
["Propylthiouracil","Sertoli Cells",1,1,"20951798",2011,"Akt1 protects against germ cell apoptosis in the postnatal mouse testis following lactational exposure to 6-N-propylthiouracil.","20951798","Propylthiouracil","Sertoli Cells",1,1,1]
["Propylthiouracil","Sertoli Cells",0,1,"8294229",1993,"Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse.","8294229","Propylthiouracil","Sertoli Cells",1,1,1]
["Propylthiouracil","Sperm Count",1,1,"22042771",2012,"Treatment with folic acid ameliorated the histopathological alterations caused by propylthiouracil-induced hypothyroid rat testes.","22042771","Propylthiouracil","Sperm Count",1,1,1]
["Propylthiouracil","Sperm Count",0,1,"9615182",1998,"Effects of 6-N-propyl-2-thiouracil on growth, hormonal profiles, carcass and reproductive traits of boars.","9615182","Propylthiouracil","Sperm Count",1,1,1]
["Propylthiouracil","Spermatids",0,1,"11861520",2002,"The goitrogen 6-n-propyl-2-thiouracil (PTU) given during testis development increases Sertoli and germ cell numbers per cyst in fish: the tilapia (Oreochromis niloticus) model.","11861520","Propylthiouracil","Spermatids",1,1,1]
["Propylthiouracil","Spermatocytes",0,1,"11861520",2002,"The goitrogen 6-n-propyl-2-thiouracil (PTU) given during testis development increases Sertoli and germ cell numbers per cyst in fish: the tilapia (Oreochromis niloticus) model.","11861520","Propylthiouracil","Spermatocytes",1,1,1]
["Propylthiouracil","Spermatogenesis",0,1,"1547312",1992,"Induction of increased testis growth and sperm production in adult rats by neonatal administration of the goitrogen propylthiouracil (PTU): the critical period.","1547312","Propylthiouracil","Spermatogenesis",1,1,1]
["Propylthiouracil","Spermatogenesis",0,1,"20525087",2010,"Postnatal testis development, Sertoli cell proliferation and number of different spermatogonial types in C57BL/6J mice made transiently hypo- and hyperthyroidic during the neonatal period.","20525087","Propylthiouracil","Spermatogenesis",1,1,1]
["Propylthiouracil","Spermatogenesis",0,1,"7595279",1995,"Effect of hypothyroidism induced by propylthiouracil and thiourea on male and female reproductive systems of neonatal mice.","7595279","Propylthiouracil","Spermatogenesis",1,1,1]
["Propylthiouracil","Spermatogenesis",0,1,"8294229",1993,"Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse.","8294229","Propylthiouracil","Spermatogenesis",1,1,1]
["Propylthiouracil","Spermatogenesis",0,1,"8501721",1993,"Increased testis growth and sperm production in adult rats following transient neonatal goitrogen treatment: optimization of the propylthiouracil dose and effects of methimazole.","8501721","Propylthiouracil","Spermatogenesis",1,1,1]
["Propylthiouracil","Spermatozoa",0,1,"10404680",1999,"Effects of transient treatment with 6-N-propyl-2-thiouracil on testis development and function in breeder turkeys.","10404680","Propylthiouracil","Spermatozoa",1,1,1]
["Propylthiouracil","Spermatozoa",0,1,"11869372",2002,"Are germ cell factors essential in the testicular enlargement after neonatal hypothyroidism recovery? A study using W/Wv mutant mice model.","11869372","Propylthiouracil","Spermatozoa",1,1,1]
["Propylthiouracil","Spermatozoa",1,1,"18292836",2007,"Comparative study of the effects of pre and post natal administration of a thyroid drug on testicular activity in adult rat.","18292836","Propylthiouracil","Spermatozoa",1,1,1]
["Propylthiouracil","Spermatozoa",1,1,"20951798",2011,"Akt1 protects against germ cell apoptosis in the postnatal mouse testis following lactational exposure to 6-N-propylthiouracil.","20951798","Propylthiouracil","Spermatozoa",1,1,1]
["Propylthiouracil","Spermatozoa",1,1,"22042771",2012,"Treatment with folic acid ameliorated the histopathological alterations caused by propylthiouracil-induced hypothyroid rat testes.","22042771","Propylthiouracil","Spermatozoa",1,1,1]
["Propylthiouracil","Testis",0,1,"10404680",1999,"Effects of transient treatment with 6-N-propyl-2-thiouracil on testis development and function in breeder turkeys.","10404680","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",0,1,"11861520",2002,"The goitrogen 6-n-propyl-2-thiouracil (PTU) given during testis development increases Sertoli and germ cell numbers per cyst in fish: the tilapia (Oreochromis niloticus) model.","11861520","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",0,1,"11869372",2002,"Are germ cell factors essential in the testicular enlargement after neonatal hypothyroidism recovery? A study using W/Wv mutant mice model.","11869372","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",0,1,"1547312",1992,"Induction of increased testis growth and sperm production in adult rats by neonatal administration of the goitrogen propylthiouracil (PTU): the critical period.","1547312","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",1,1,"18292836",2007,"Comparative study of the effects of pre and post natal administration of a thyroid drug on testicular activity in adult rat.","18292836","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",0,1,"20525087",2010,"Postnatal testis development, Sertoli cell proliferation and number of different spermatogonial types in C57BL/6J mice made transiently hypo- and hyperthyroidic during the neonatal period.","20525087","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",1,1,"20951798",2011,"Akt1 protects against germ cell apoptosis in the postnatal mouse testis following lactational exposure to 6-N-propylthiouracil.","20951798","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",1,1,"22042771",2012,"Treatment with folic acid ameliorated the histopathological alterations caused by propylthiouracil-induced hypothyroid rat testes.","22042771","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",0,1,"4796897",1973,"Effect of propylthiouracil-induced hypothyroidism on serum levels of luteinizing hormone and follicle-stimulating hormone in the rat.","4796897","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",0,1,"7595279",1995,"Effect of hypothyroidism induced by propylthiouracil and thiourea on male and female reproductive systems of neonatal mice.","7595279","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",0,1,"8294229",1993,"Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse.","8294229","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Testis",0,1,"8501721",1993,"Increased testis growth and sperm production in adult rats following transient neonatal goitrogen treatment: optimization of the propylthiouracil dose and effects of methimazole.","8501721","Propylthiouracil","Testis",1,1,1]
["Propylthiouracil","Turner Syndrome",1,0,"16418614",2006,"PTU-associated vasculitis in a girl with Turner Syndrome and Graves' disease.","16418614","Propylthiouracil","Turner Syndrome",1,1,1]
["pyrazon","Spermatogenesis",1,1,"4065620",1985,"[Experimental study of the gonadotoxic action of 1-phenyl-4-amino-5-chloropyridazole-6].","4065620","pyrazon","Spermatogenesis",1,null,1]
["pyrazon","Testis",1,1,"4065620",1985,"[Experimental study of the gonadotoxic action of 1-phenyl-4-amino-5-chloropyridazole-6].","4065620","pyrazon","Testis",1,null,1]
["Simazine","Testis",1,1,"22984576",2012,"Disturbed relaxin signaling pathway and testicular dysfunction in mouse offspring upon maternal exposure to simazine.","22984576","Simazine","Testis",1,null,1]
["Sodium Nitrite","Penis",0,1,"20651825",2010,"Intracavernosal administration of sodium nitrite as an erectile pharmacotherapy.","20651825","Sodium Nitrite","Penis",1,null,1]
["Sodium Nitrite","Spermatocytes",1,1,"1410285",1992,"[Chromosome aberration induction in murine spermatocytes in joint exposure to radiation and sodium nitrite and nitrate].","1410285","Sodium Nitrite","Spermatocytes",1,null,1]
["Sulfasalazine","Acrosome",1,1,"2875031",1986,"The effect of salicylazosulphapyridine (sulphasalazine) on male fertility. A review.","2875031","Sulfasalazine","Acrosome",1,null,1]
["Sulfasalazine","Bulbourethral Glands",1,1,"2875031",1986,"The effect of salicylazosulphapyridine (sulphasalazine) on male fertility. A review.","2875031","Sulfasalazine","Bulbourethral Glands",1,null,1]
["Sulfasalazine","Epididymis",1,1,"10689203",2000,"Rat epididymal sperm motion changes induced by ethylene glycol monoethyl ether, sulfasalazine, and 2,5-hexandione.","10689203","Sulfasalazine","Epididymis",1,null,1]
["Sulfasalazine","Epididymis",1,1,"17166698",2007,"Early changes in sperm motility, acrosome reaction, and gene expression of reproductive organs in rats treated with sulfasalazine.","17166698","Sulfasalazine","Epididymis",1,null,1]
["Sulfasalazine","Epididymis",1,1,"19028562",2009,"Sulfasalazine induced oxidative stress: a possible mechanism of male infertility.","19028562","Sulfasalazine","Epididymis",1,null,1]
["Sulfasalazine","Genitalia, Male",1,1,"15625186",2005,"Effects of sulfasalazine on sperm acrosome reaction and gene expression in the male reproductive organs of rats.","15625186","Sulfasalazine","Genitalia, Male",1,null,1]
["Sulfasalazine","Seminiferous Epithelium",0,1,"16626516",2006,"Sulfasalazine prevents apoptosis in spermatogenic cells after experimental testicular torsion/detorsion.","16626516","Sulfasalazine","Seminiferous Epithelium",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"10689203",2000,"Rat epididymal sperm motion changes induced by ethylene glycol monoethyl ether, sulfasalazine, and 2,5-hexandione.","10689203","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"19028562",2009,"Sulfasalazine induced oxidative stress: a possible mechanism of male infertility.","19028562","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"2889648",1987,"Sulphasalazine induced seminal abnormalities in ulcerative colitis: results of mesalazine substitution.","2889648","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"6114897",1981,"Sulphasalazine and male infertility: reversibility and possible mechanism.","6114897","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",0,1,"6126966",1982,"[(Quality of semen in patients with Crohn's disease) ].","6126966","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"6142578",1983,"Male infertility due to sulphasalazine therapy of ulcerous colitis.","6142578","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"6147421",1984,"The effects of sulfasalazine on human male fertility potential and seminal prostaglandins.","6147421","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"6148293",1984,"Reversible male infertility due to sulphasalazine: studies in man and rat.","6148293","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"6168127",1981,"[The effect of salazosulfapyridine on fertility].","6168127","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"7901410",1993,"Effect of sulphasalazine upon seminal characteristics in dogs.","7901410","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"90305",1979,"Male infertility due to sulphasalazine.","90305","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Count",1,1,"9114353",1997,"Reproductive toxicology. Salicylazosulfapyridine.","9114353","Sulfasalazine","Sperm Count",1,null,1]
["Sulfasalazine","Sperm Head",1,1,"6124462",1982,"Sperm size in patients with inflammatory bowel disease on sulfasalazine therapy.","6124462","Sulfasalazine","Sperm Head",1,null,1]
["Sulfasalazine","Sperm Head",1,1,"6151915",1984,"Side-effects of salazopyrin on male fertility.","6151915","Sulfasalazine","Sperm Head",1,null,1]
["Sulfasalazine","Sperm Maturation",1,1,"6151915",1984,"Side-effects of salazopyrin on male fertility.","6151915","Sulfasalazine","Sperm Maturation",1,null,1]
["Sulfasalazine","Sperm Maturation",1,1,"90305",1979,"Male infertility due to sulphasalazine.","90305","Sulfasalazine","Sperm Maturation",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"10689203",2000,"Rat epididymal sperm motion changes induced by ethylene glycol monoethyl ether, sulfasalazine, and 2,5-hexandione.","10689203","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"15625186",2005,"Effects of sulfasalazine on sperm acrosome reaction and gene expression in the male reproductive organs of rats.","15625186","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"17166698",2007,"Early changes in sperm motility, acrosome reaction, and gene expression of reproductive organs in rats treated with sulfasalazine.","17166698","Sulfasalazine","Sperm Motility",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I4036,I4036)","v":"Sulfasalazine"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J4036,J4036)","v":"Sperm Motility"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H4036,H4036)","v":"19028562"},2009,"Sulfasalazine induced oxidative stress: a possible mechanism of male infertility.","19028562","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"2889648",1987,"Sulphasalazine induced seminal abnormalities in ulcerative colitis: results of mesalazine substitution.","2889648","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"2905767",1988,"[Fertility disorders in man during treatment with sufasalazine].","2905767","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"36307",1979,"Reversible toxic effect of salicylazosulfapyridine on semen quality.","36307","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"6114897",1981,"Sulphasalazine and male infertility: reversibility and possible mechanism.","6114897","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"6121309",1982,"Reversible male infertility.","6121309","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",0,1,"6126966",1982,"[(Quality of semen in patients with Crohn's disease) ].","6126966","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"6142578",1983,"Male infertility due to sulphasalazine therapy of ulcerous colitis.","6142578","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"6147421",1984,"The effects of sulfasalazine on human male fertility potential and seminal prostaglandins.","6147421","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"6148293",1984,"Reversible male infertility due to sulphasalazine: studies in man and rat.","6148293","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"6168127",1981,"[The effect of salazosulfapyridine on fertility].","6168127","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"7889088",1994,"Spermatozoal abnormalities and male infertility in the rat following sulfasalazine treatment.","7889088","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"88609",1979,"Male infertility due to sulphasalazine.","88609","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Sperm Motility",1,1,"90305",1979,"Male infertility due to sulphasalazine.","90305","Sulfasalazine","Sperm Motility",1,null,1]
["Sulfasalazine","Spermatocytes",0,1,"16626516",2006,"Sulfasalazine prevents apoptosis in spermatogenic cells after experimental testicular torsion/detorsion.","16626516","Sulfasalazine","Spermatocytes",1,null,1]
["Sulfasalazine","Spermatogenesis",1,1,"11868809",2002,"The adverse effect of sulfasalazine on spermatogenesis and male reproductive potential.","11868809","Sulfasalazine","Spermatogenesis",1,null,1]
["Sulfasalazine","Spermatogenesis",1,1,"1976537",1990,"Effect of sulfasalazine on spermatogenesis.","1976537","Sulfasalazine","Spermatogenesis",1,null,1]
["Sulfasalazine","Spermatogenesis",1,1,"6123457",1982,"Sulphasalazine and spermatogenesis.","6123457","Sulfasalazine","Spermatogenesis",1,null,1]
["Sulfasalazine","Spermatogenesis",0,1,"6126966",1982,"[(Quality of semen in patients with Crohn's disease) ].","6126966","Sulfasalazine","Spermatogenesis",1,null,1]
["Sulfasalazine","Spermatogenesis",1,1,"6130639",1982,"[Sulfasalazine-induced male infertility].","6130639","Sulfasalazine","Spermatogenesis",1,null,1]
["Sulfasalazine","Spermatogenesis",1,1,"6142578",1983,"Male infertility due to sulphasalazine therapy of ulcerous colitis.","6142578","Sulfasalazine","Spermatogenesis",1,null,1]
["Sulfasalazine","Spermatogenesis",1,1,"6151915",1984,"Side-effects of salazopyrin on male fertility.","6151915","Sulfasalazine","Spermatogenesis",1,null,1]
["Sulfasalazine","Spermatogenesis",1,1,"88609",1979,"Male infertility due to sulphasalazine.","88609","Sulfasalazine","Spermatogenesis",1,null,1]
["Sulfasalazine","Spermatogenesis",0,1,"8920079",1996,"[Salazopyrine and male fertility].","8920079","Sulfasalazine","Spermatogenesis",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"15625186",2005,"Effects of sulfasalazine on sperm acrosome reaction and gene expression in the male reproductive organs of rats.","15625186","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"19028562",2009,"Sulfasalazine induced oxidative stress: a possible mechanism of male infertility.","19028562","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"2572460",1989,"Inflammatory bowel disease and male infertility: effects of sulfasalazine and 5-aminosalicylic acid on sperm-fertilizing capacity and reactive oxygen species generation.","2572460","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"2889648",1987,"Sulphasalazine induced seminal abnormalities in ulcerative colitis: results of mesalazine substitution.","2889648","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"2905767",1988,"[Fertility disorders in man during treatment with sufasalazine].","2905767","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"36307",1979,"Reversible toxic effect of salicylazosulfapyridine on semen quality.","36307","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"6112875",1980,"Azulfidine-induced oligospermia.","6112875","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"6114476",1981,"[Anomalies of the spermogram and sterility caused by salazopyrine].","6114476","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"6114897",1981,"Sulphasalazine and male infertility: reversibility and possible mechanism.","6114897","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"6114898",1981,"Incidence of sulphasalazine-induced male infertility.","6114898","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"6124462",1982,"Sperm size in patients with inflammatory bowel disease on sulfasalazine therapy.","6124462","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"6147421",1984,"The effects of sulfasalazine on human male fertility potential and seminal prostaglandins.","6147421","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",0,1,"6152053",1984,"Comparative study of antiinflammatory drugs and sulphasalazine in relation to prostaglandin E and 19 hydroxylated prostaglandin E levels and human male fertility.","6152053","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"7889088",1994,"Spermatozoal abnormalities and male infertility in the rat following sulfasalazine treatment.","7889088","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"7901410",1993,"Effect of sulphasalazine upon seminal characteristics in dogs.","7901410","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"89517",1979,"Male infertility due to sulphasalazine.","89517","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"90305",1979,"Male infertility due to sulphasalazine.","90305","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Spermatozoa",1,1,"9114353",1997,"Reproductive toxicology. Salicylazosulfapyridine.","9114353","Sulfasalazine","Spermatozoa",1,null,1]
["Sulfasalazine","Testis",1,1,"10689203",2000,"Rat epididymal sperm motion changes induced by ethylene glycol monoethyl ether, sulfasalazine, and 2,5-hexandione.","10689203","Sulfasalazine","Testis",1,null,1]
["Sulfasalazine","Testis",1,1,"17166698",2007,"Early changes in sperm motility, acrosome reaction, and gene expression of reproductive organs in rats treated with sulfasalazine.","17166698","Sulfasalazine","Testis",1,null,1]
["Sulfasalazine","Testis",1,1,"19028562",2009,"Sulfasalazine induced oxidative stress: a possible mechanism of male infertility.","19028562","Sulfasalazine","Testis",1,null,1]
["Sulfasalazine","Testis",1,1,"2875031",1986,"The effect of salicylazosulphapyridine (sulphasalazine) on male fertility. A review.","2875031","Sulfasalazine","Testis",1,null,1]
["Sulfasalazine","Testis",1,1,"9114353",1997,"Reproductive toxicology. Salicylazosulfapyridine.","9114353","Sulfasalazine","Testis",1,null,1]
["systhane","Genitalia, Male",1,1,"17018648",2007,"Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat.","17018648","systhane","Genitalia, Male",1,null,1]
["systhane","Sperm Motility",1,1,"17018648",2007,"Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat.","17018648","systhane","Sperm Motility",1,null,1]
["systhane","Spermatozoa",1,1,"17018648",2007,"Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat.","17018648","systhane","Spermatozoa",1,null,1]
["systhane","Testis",1,1,"19423681",2009,"Mode of action for reproductive and hepatic toxicity inferred from a genomic study of triazole antifungals.","19423681","systhane","Testis",1,null,1]
["tebufenozide","Spermatozoa",0,1,"15183280",2004,"Effects of larval exposure to sublethal concentrations of the ecdysteroid agonists RH-5849 and tebufenozide (RH-5992) on male reproductive physiology in Spodoptera litura.","15183280","tebufenozide","Spermatozoa",1,null,1]
["tebufenozide","Testis",0,1,"15183280",2004,"Effects of larval exposure to sublethal concentrations of the ecdysteroid agonists RH-5849 and tebufenozide (RH-5992) on male reproductive physiology in Spodoptera litura.","15183280","tebufenozide","Testis",1,null,1]
["Testosterone Propionate","Blood-Testis Barrier",0,1,"18292837",2007,"During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.","18292837","Testosterone Propionate","Blood-Testis Barrier",1,null,1]
["Testosterone Propionate","Seminiferous Tubules",0,1,"18292837",2007,"During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.","18292837","Testosterone Propionate","Seminiferous Tubules",1,null,1]
["Testosterone Propionate","Seminiferous Tubules",0,1,"21535008",2011,"Testosterone and oestradiol in concert protect seminiferous tubule maturation against inhibition by GnRH-antagonist.","21535008","Testosterone Propionate","Seminiferous Tubules",1,null,1]
["Testosterone Propionate","Seminiferous Tubules",0,1,"24011196",2013,"Estradiol and testosterone inhibit rat seminiferous tubule development in a hormone-specific way.","24011196","Testosterone Propionate","Seminiferous Tubules",1,null,1]
["Testosterone Propionate","Sertoli Cells",0,1,"18292837",2007,"During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.","18292837","Testosterone Propionate","Sertoli Cells",1,null,1]
["Testosterone Propionate","Sertoli Cells",0,1,"21535008",2011,"Testosterone and oestradiol in concert protect seminiferous tubule maturation against inhibition by GnRH-antagonist.","21535008","Testosterone Propionate","Sertoli Cells",1,null,1]
["Testosterone Propionate","Spermatogenesis",0,1,"16176578",2005,"Neonatal androgenization of hypogonadal (hpg) male mice does not abolish estradiol-induced FSH production and spermatogenesis.","16176578","Testosterone Propionate","Spermatogenesis",1,null,1]
["Testosterone Propionate","Spermatogenesis",0,1,"21535008",2011,"Testosterone and oestradiol in concert protect seminiferous tubule maturation against inhibition by GnRH-antagonist.","21535008","Testosterone Propionate","Spermatogenesis",1,null,1]
["Testosterone Propionate","Spermatogenesis",0,1,"24011196",2013,"Estradiol and testosterone inhibit rat seminiferous tubule development in a hormone-specific way.","24011196","Testosterone Propionate","Spermatogenesis",1,null,1]
["Testosterone Propionate","Spermatozoa",0,1,"18292837",2007,"During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.","18292837","Testosterone Propionate","Spermatozoa",1,null,1]
["Testosterone Propionate","Spermatozoa",1,1,"18513952",2008,"Androgenic profile and genotoxicity evaluation of testosterone propionate and novel synthesized heterocyclic steroids.","18513952","Testosterone Propionate","Spermatozoa",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I4100,I4100)","v":"Testosterone Propionate"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J4100,J4100)","v":"Spermatozoa"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H4100,H4100)","v":"24011196"},2013,"Estradiol and testosterone inhibit rat seminiferous tubule development in a hormone-specific way.","24011196","Testosterone Propionate","Spermatozoa",1,null,1]
["Testosterone Propionate","Testis",0,1,"16176578",2005,"Neonatal androgenization of hypogonadal (hpg) male mice does not abolish estradiol-induced FSH production and spermatogenesis.","16176578","Testosterone Propionate","Testis",1,null,1]
["Testosterone Propionate","Testis",1,1,"18513952",2008,"Androgenic profile and genotoxicity evaluation of testosterone propionate and novel synthesized heterocyclic steroids.","18513952","Testosterone Propionate","Testis",1,null,1]
["Testosterone Propionate","Testis",0,1,"24011196",2013,"Estradiol and testosterone inhibit rat seminiferous tubule development in a hormone-specific way.","24011196","Testosterone Propionate","Testis",1,null,1]
["thidiazuron","Sperm Motility",1,1,"6706170",1984,"[Hygienic regulation of the defoliant drop in the water].","6706170","thidiazuron","Sperm Motility",1,null,1]
["Thiram","Sperm Head",0,1,"7144781",1982,"Thiram-induced sperm-head abnormalities in mice.","7144781","Thiram","Sperm Head",1,null,1]
["Thiram","Sperm Head",1,1,"7702762",1994,"No evidence of effect on male mice germ cells after acute treatment with thiram.","7702762","Thiram","Sperm Head",1,null,1]
["Thiram","Spermatocytes",1,1,"3653825",1987,"The effect of thiram on the germ cells of male mice.","3653825","Thiram","Spermatocytes",1,null,1]
["Thiram","Spermatogenesis",1,1,"7364288",1980,"[Mutagenic and gonadotropic action of thiuram EF].","7364288","Thiram","Spermatogenesis",1,null,1]
["Thiram","Spermatogenesis",1,1,"8226114",1993,"Testicular toxicity of thiram in rat: morphological and biochemical evaluations.","8226114","Thiram","Spermatogenesis",1,null,1]
["Thiram","Spermatogenesis",1,1,"9216752",1997,"Assessment of mutagenic potential of thiram.","9216752","Thiram","Spermatogenesis",1,null,1]
["Thiram","Spermatogonia",1,1,"14593654",2003,"[Calculating risk and relative genetic effects of some alkylating agents].","14593654","Thiram","Spermatogonia",1,null,1]
["Thiram","Spermatozoa",1,1,"3653825",1987,"The effect of thiram on the germ cells of male mice.","3653825","Thiram","Spermatozoa",1,null,1]
["Thiram","Spermatozoa",1,1,"7702762",1994,"No evidence of effect on male mice germ cells after acute treatment with thiram.","7702762","Thiram","Spermatozoa",1,null,1]
["Thiram","Testis",1,1,"7364288",1980,"[Mutagenic and gonadotropic action of thiuram EF].","7364288","Thiram","Testis",1,null,1]
["Thiram","Testis",1,1,"7702762",1994,"No evidence of effect on male mice germ cells after acute treatment with thiram.","7702762","Thiram","Testis",1,null,1]
["Thiram","Testis",1,1,"8226114",1993,"Testicular toxicity of thiram in rat: morphological and biochemical evaluations.","8226114","Thiram","Testis",1,null,1]
["Tretinoin","Blood-Testis Barrier",0,1,"23095883",2012,"Retinoic acid signaling in Sertoli cells regulates organization of the blood-testis barrier through cyclical changes in gene expression.","23095883","Tretinoin","Blood-Testis Barrier",1,null,1]
["Tretinoin","Cryptorchidism",0,1,"6129843",1982,"Etinoic acid (vitamin A acid) induces spermatogenesis in adult mouse cryptorchid testes in vitro.","6129843","Tretinoin","Cryptorchidism",1,null,1]
["Tretinoin","Disorders of Sex Development",1,1,"18085413",2008,"Exposure to 9-cis retinoic acid induces penis and vas deferens development in the female rock shell, Thais clavigera.","18085413","Tretinoin","Disorders of Sex Development",1,null,1]
["Tretinoin","Genitalia, Male",1,1,"11795391",2001,"External genitalia formation: role of fibroblast growth factor, retinoic acid signaling, and distal urethral epithelium.","11795391","Tretinoin","Genitalia, Male",1,null,1]
["Tretinoin","Hyperandrogenism",0,0,"15914525",2005,"Retinoids and retinol differentially regulate steroid biosynthesis in ovarian theca cells isolated from normal cycling women and women with polycystic ovary syndrome.","15914525","Tretinoin","Hyperandrogenism",1,null,1]
["Tretinoin","Leydig Cells",0,1,"14960491",2004,"Retinoid-sensitive steps in steroidogenesis in fetal and neonatal rat testes: in vitro and in vivo studies.","14960491","Tretinoin","Leydig Cells",1,null,1]
["Tretinoin","Leydig Cells",0,1,"16621909",2006,"Use of organ culture to study the human fetal testis development: effect of retinoic acid.","16621909","Tretinoin","Leydig Cells",1,null,1]
["Tretinoin","Penis",1,1,"18085413",2008,"Exposure to 9-cis retinoic acid induces penis and vas deferens development in the female rock shell, Thais clavigera.","18085413","Tretinoin","Penis",1,null,1]
["Tretinoin","Penis",1,1,"2627062",1989,"[Penile agenesis and syndrome of multiple abnormalities associated with the ingestion of retinoic acid by the mother].","2627062","Tretinoin","Penis",1,null,1]
["Tretinoin","Seminiferous Epithelium",1,1,"16432891",2006,"Impairment of spermatogenesis and enhancement of testicular germ cell apoptosis induced by exogenous all-trans-retinoic acid in adult lizard Podarcis sicula.","16432891","Tretinoin","Seminiferous Epithelium",1,null,1]
["Tretinoin","Seminiferous Epithelium",0,1,"22200512",2012,"Retinoic acid metabolism links the periodical differentiation of germ cells with the cycle of Sertoli cells in mouse seminiferous epithelium.","22200512","Tretinoin","Seminiferous Epithelium",1,null,1]
["Tretinoin","Seminiferous Epithelium",0,1,"23095883",2012,"Retinoic acid signaling in Sertoli cells regulates organization of the blood-testis barrier through cyclical changes in gene expression.","23095883","Tretinoin","Seminiferous Epithelium",1,null,1]
["Tretinoin","Seminiferous Epithelium",0,1,"23511242",2013,"Retinoic acid regulation of male meiosis.","23511242","Tretinoin","Seminiferous Epithelium",1,null,1]
["Tretinoin","Seminiferous Tubules",0,1,"1989855",1991,"Retinoic acid is able to reinitiate spermatogenesis in vitamin A-deficient rats and high replicate doses support the full development of spermatogenic cells.","1989855","Tretinoin","Seminiferous Tubules",1,null,1]
["Tretinoin","Seminiferous Tubules",0,1,"20650878",2010,"Retinoic acid availability drives the asynchronous initiation of spermatogonial differentiation in the mouse.","20650878","Tretinoin","Seminiferous Tubules",1,null,1]
["Tretinoin","Seminiferous Tubules",0,1,"21228214",2011,"Exposure to retinoic acid in the neonatal but not adult mouse results in synchronous spermatogenesis.","21228214","Tretinoin","Seminiferous Tubules",1,null,1]
["Tretinoin","Seminiferous Tubules",0,1,"23095883",2012,"Retinoic acid signaling in Sertoli cells regulates organization of the blood-testis barrier through cyclical changes in gene expression.","23095883","Tretinoin","Seminiferous Tubules",1,null,1]
["Tretinoin","Sertoli Cells",0,1,"10837026",2000,"E-MAP-115, encoding a microtubule-associated protein, is a retinoic acid-inducible gene required for spermatogenesis.","10837026","Tretinoin","Sertoli Cells",1,null,1]
["Tretinoin","Sertoli Cells",0,1,"14613895",2004,"Retinoic acid inhibits rat XY gonad development by blocking mesonephric cell migration and decreasing the number of gonocytes.","14613895","Tretinoin","Sertoli Cells",1,null,1]
["Tretinoin","Sertoli Cells",0,1,"16574820",2006,"Retinoid signaling determines germ cell fate in mice.","16574820","Tretinoin","Sertoli Cells",1,null,1]
["Tretinoin","Sertoli Cells",0,1,"18032419",2008,"Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro.","18032419","Tretinoin","Sertoli Cells",1,null,1]
["Tretinoin","Sertoli Cells",0,1,"1989855",1991,"Retinoic acid is able to reinitiate spermatogenesis in vitamin A-deficient rats and high replicate doses support the full development of spermatogenic cells.","1989855","Tretinoin","Sertoli Cells",1,null,1]
["Tretinoin","Sertoli Cells",0,1,"20075418",2010,"Retinoic acid modulates the subcellular localization of small ubiquitin-related modifier-2/3 (SUMO-2/3) in the testis.","20075418","Tretinoin","Sertoli Cells",1,null,1]
["Tretinoin","Sertoli Cells",0,1,"22200512",2012,"Retinoic acid metabolism links the periodical differentiation of germ cells with the cycle of Sertoli cells in mouse seminiferous epithelium.","22200512","Tretinoin","Sertoli Cells",1,null,1]
["Tretinoin","Sertoli Cells",0,1,"22262692",2012,"Male differentiation of germ cells induced by embryonic age-specific Sertoli cells in mice.","22262692","Tretinoin","Sertoli Cells",1,null,1]
["Tretinoin","Sertoli Cells",0,1,"23012458",2012,"Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.","23012458","Tretinoin","Sertoli Cells",1,null,1]
["Tretinoin","Sertoli Cells",0,1,"23095883",2012,"Retinoic acid signaling in Sertoli cells regulates organization of the blood-testis barrier through cyclical changes in gene expression.","23095883","Tretinoin","Sertoli Cells",1,null,1]
["Tretinoin","Sperm Count",0,1,"1593535",1992,"Spermatogenesis in retinol-deficient rats maintained on retinoic acid.","1593535","Tretinoin","Sperm Count",1,null,1]
["Tretinoin","Sperm Count",0,1,"24478393",2014,"Retinoic acid induces multiple hallmarks of the prospermatogonia-to-spermatogonia transition in the neonatal mouse.","24478393","Tretinoin","Sperm Count",1,null,1]
["Tretinoin","Sperm Count",0,1,"3159708",1985,"[13-cis-Retinoic acid and spermatogenesis. Spermatological and impulse cytophotometric studies].","3159708","Tretinoin","Sperm Count",1,null,1]
["Tretinoin","Sperm Count",1,1,"3481225",1987,"Spermatological investigations in patients treated with etretinate and isotretinoin.","3481225","Tretinoin","Sperm Count",1,null,1]
["Tretinoin","Sperm Count",0,1,"4078142",1985,"[Quantitative study of spermatogenesis in rats developing avitaminosis A from the use of retinoic acid].","4078142","Tretinoin","Sperm Count",1,null,1]
["Tretinoin","Sperm Maturation",0,1,"24478393",2014,"Retinoic acid induces multiple hallmarks of the prospermatogonia-to-spermatogonia transition in the neonatal mouse.","24478393","Tretinoin","Sperm Maturation",1,null,1]
["Tretinoin","Sperm Motility",1,1,"2149914",1990,"Andrological investigations in men treated with acitretin (Ro 10-1670).","2149914","Tretinoin","Sperm Motility",1,null,1]
["Tretinoin","Sperm Motility",1,1,"3481225",1987,"Spermatological investigations in patients treated with etretinate and isotretinoin.","3481225","Tretinoin","Sperm Motility",1,null,1]
["Tretinoin","Sperm Motility",0,1,"4459289",1974,"Incorporation of labelled retinol and retinoic acid in bovine spermatozoa effect of zinc on the rate of incorporation.","4459289","Tretinoin","Sperm Motility",1,null,1]
["Tretinoin","Spermatic Cord",0,1,"8522071",1995,"Retinoic acid affects basement membrane formation of the seminiferous cords in 14-day male rat gonads in vitro.","8522071","Tretinoin","Spermatic Cord",1,null,1]
["Tretinoin","Spermatocytes",0,1,"1593535",1992,"Spermatogenesis in retinol-deficient rats maintained on retinoic acid.","1593535","Tretinoin","Spermatocytes",1,null,1]
["Tretinoin","Spermatocytes",0,1,"17332523",2007,"Utilization of DR1 as true RARE in regulating the Ssm, a novel retinoic acid-target gene in the mouse testis.","17332523","Tretinoin","Spermatocytes",1,null,1]
["Tretinoin","Spermatocytes",0,1,"1821852",1991,"Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytes.","1821852","Tretinoin","Spermatocytes",1,null,1]
["Tretinoin","Spermatocytes",0,1,"1989855",1991,"Retinoic acid is able to reinitiate spermatogenesis in vitamin A-deficient rats and high replicate doses support the full development of spermatogenic cells.","1989855","Tretinoin","Spermatocytes",1,null,1]
["Tretinoin","Spermatocytes",0,1,"23012458",2012,"Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.","23012458","Tretinoin","Spermatocytes",1,null,1]
["Tretinoin","Spermatocytes",0,1,"24711451",2014,"Inhibition of retinoic acid biosynthesis by the bisdichloroacetyldiamine WIN 18,446 markedly suppresses spermatogenesis and alters retinoid metabolism in mice.","24711451","Tretinoin","Spermatocytes",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"1062881",1975,"Aspects of teratology of vitamin A acid (beta-all-trans retinoic acid).","1062881","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"10837026",2000,"E-MAP-115, encoding a microtubule-associated protein, is a retinoic acid-inducible gene required for spermatogenesis.","10837026","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"1593535",1992,"Spermatogenesis in retinol-deficient rats maintained on retinoic acid.","1593535","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",1,1,"16432891",2006,"Impairment of spermatogenesis and enhancement of testicular germ cell apoptosis induced by exogenous all-trans-retinoic acid in adult lizard Podarcis sicula.","16432891","Tretinoin","Spermatogenesis",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I4164,I4164)","v":"Tretinoin"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J4164,J4164)","v":"Spermatogenesis"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H4164,H4164)","v":"16574820"},2006,"Retinoid signaling determines germ cell fate in mice.","16574820","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"16621909",2006,"Use of organ culture to study the human fetal testis development: effect of retinoic acid.","16621909","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"18032419",2008,"Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro.","18032419","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"18322276",2008,"Expression of stimulated by retinoic acid gene 8 (Stra8) in spermatogenic cells induced by retinoic acid: an in vivo study in vitamin A-sufficient postnatal murine testes.","18322276","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"18799751",2008,"Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice.","18799751","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"19098446",2008,"ATRA and KL promote differentiation toward the meiotic program of male germ cells.","19098446","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"1989855",1991,"Retinoic acid is able to reinitiate spermatogenesis in vitamin A-deficient rats and high replicate doses support the full development of spermatogenic cells.","1989855","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",1,1,"1996464",1991,"Time course of testicular degeneration in rats induced by a synthetic retinoid (Ro 23-2895) and evidence for induction of hypovitaminosis A in the testes.","1996464","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"20650878",2010,"Retinoic acid availability drives the asynchronous initiation of spermatogonial differentiation in the mouse.","20650878","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"20705791",2011,"Suppression of spermatogenesis by bisdichloroacetyldiamines is mediated by inhibition of testicular retinoic acid biosynthesis.","20705791","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"20844280",2010,"New insights into the regulation of gametogenesis by retinoic acid.","20844280","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"21091440",2011,"Retinoic acid induces myoblasts transdifferentiation into premeiotic Stra8-positive cells.","21091440","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"21228214",2011,"Exposure to retinoic acid in the neonatal but not adult mouse results in synchronous spermatogenesis.","21228214","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",1,1,"2149914",1990,"Andrological investigations in men treated with acitretin (Ro 10-1670).","2149914","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"22075477",2012,"Initiating meiosis: the case for retinoic acid.","22075477","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"22232934",2011,"[The mammalian gonocytes fate: oogenesis or spermatogenesis].","22232934","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"23095883",2012,"Retinoic acid signaling in Sertoli cells regulates organization of the blood-testis barrier through cyclical changes in gene expression.","23095883","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"23441462",2013,"[Signaling pathway of meiosis induced by retinoic acid during spermatogenesis].","23441462","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"23511242",2013,"Retinoic acid regulation of male meiosis.","23511242","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"24478393",2014,"Retinoic acid induces multiple hallmarks of the prospermatogonia-to-spermatogonia transition in the neonatal mouse.","24478393","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"24711451",2014,"Inhibition of retinoic acid biosynthesis by the bisdichloroacetyldiamine WIN 18,446 markedly suppresses spermatogenesis and alters retinoid metabolism in mice.","24711451","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"3159708",1985,"[13-cis-Retinoic acid and spermatogenesis. Spermatological and impulse cytophotometric studies].","3159708","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",1,1,"3744176",1986,"Effect of vitamin A acid on the testis of the Egyptian toad.","3744176","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"3857793",1985,"[Light microscopic studies of spermatogenesis in rats following the administration of a high dose of 13-cis-retinoic acid].","3857793","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"4078142",1985,"[Quantitative study of spermatogenesis in rats developing avitaminosis A from the use of retinoic acid].","4078142","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"6129843",1982,"Etinoic acid (vitamin A acid) induces spermatogenesis in adult mouse cryptorchid testes in vitro.","6129843","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",1,1,"6223453",1983,"[Effect of drugs on spermatogenetic function].","6223453","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"6868728",1983,"[Effect of aromatic retinoid on spermatogenesis in rats. Light microscopy findings in the testes (including some other selected organs)].","6868728","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"7406530",1980,"[Reversible impairment of spermatogenesis induced by aromatic retinoid in guinea pigs (author's transl)].","7406530","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"8896602",1996,"Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acid-responsive gene.","8896602","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"9075714",1997,"Effect of retinoid status on the messenger ribonucleic acid expression of nuclear retinoid receptors alpha, beta, and gamma, and retinoid X receptors alpha, beta, and gamma in the mouse testis.","9075714","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"9547504",1998,"Isolation and characterization of all-trans-retinoic acid-responsive genes in the rat testis.","9547504","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogenesis",0,1,"9751509",1998,"The effect of 9-cis-retinoic acid on proliferation and differentiation of a spermatogonia and retinoid receptor gene expression in the vitamin A-deficient mouse testis.","9751509","Tretinoin","Spermatogenesis",1,null,1]
["Tretinoin","Spermatogonia",0,1,"1593535",1992,"Spermatogenesis in retinol-deficient rats maintained on retinoic acid.","1593535","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"17822036",2007,"[Activation of Stra 8 gene during the differentiation of spermatogonial stem cells].","17822036","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"18032419",2008,"Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro.","18032419","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"18322276",2008,"Expression of stimulated by retinoic acid gene 8 (Stra8) in spermatogenic cells induced by retinoic acid: an in vivo study in vitamin A-sufficient postnatal murine testes.","18322276","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"18719224",2008,"Spermatogonial stem cell self-renewal requires OCT4, a factor downregulated during retinoic acid-induced differentiation.","18719224","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"19098446",2008,"ATRA and KL promote differentiation toward the meiotic program of male germ cells.","19098446","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"1989855",1991,"Retinoic acid is able to reinitiate spermatogenesis in vitamin A-deficient rats and high replicate doses support the full development of spermatogenic cells.","1989855","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"20650878",2010,"Retinoic acid availability drives the asynchronous initiation of spermatogonial differentiation in the mouse.","20650878","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"21091440",2011,"Retinoic acid induces myoblasts transdifferentiation into premeiotic Stra8-positive cells.","21091440","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"21228214",2011,"Exposure to retinoic acid in the neonatal but not adult mouse results in synchronous spermatogenesis.","21228214","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"22200512",2012,"Retinoic acid metabolism links the periodical differentiation of germ cells with the cycle of Sertoli cells in mouse seminiferous epithelium.","22200512","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"23012458",2012,"Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.","23012458","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"23221399",2013,"MicroRNA 146 (Mir146) modulates spermatogonial differentiation by retinoic acid in mice.","23221399","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"24056063",2013,"Retinoic acid homeostasis regulates meiotic entry in developing anuran gonads and in Bidder's organ through Raldh2 and Cyp26b1 proteins.","24056063","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"24161026",2013,"c-kit expression profile and regulatory factors during spermatogonial stem cell differentiation.","24161026","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"24478393",2014,"Retinoic acid induces multiple hallmarks of the prospermatogonia-to-spermatogonia transition in the neonatal mouse.","24478393","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"8593792",1996,"All-trans-4-oxo-retinoic acid: a potent inducer of in vivo proliferation of growth-arrested A spermatogonia in the vitamin A-deficient mouse testis.","8593792","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatogonia",0,1,"9751509",1998,"The effect of 9-cis-retinoic acid on proliferation and differentiation of a spermatogonia and retinoid receptor gene expression in the vitamin A-deficient mouse testis.","9751509","Tretinoin","Spermatogonia",1,null,1]
["Tretinoin","Spermatozoa",1,1,"157723",1979,"[Oral treatment with tretinoin: andrological, trichological, ophthalmological findings and effects on acne (author's transl)].","157723","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"18256537",2008,"Retinoic acid prevents germ cell mitotic arrest in mouse fetal testes.","18256537","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"18425777",2009,"Expression profile of male germ cell-associated genes in mouse embryonic stem cell cultures treated with all-trans retinoic acid and testosterone.","18425777","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"20075418",2010,"Retinoic acid modulates the subcellular localization of small ubiquitin-related modifier-2/3 (SUMO-2/3) in the testis.","20075418","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"20159962",2010,"Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells.","20159962","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"20826729",2010,"Direct effects of retinoic acid on entry of fetal male germ cells into meiosis in mice.","20826729","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"20844280",2010,"New insights into the regulation of gametogenesis by retinoic acid.","20844280","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",1,1,"2149914",1990,"Andrological investigations in men treated with acitretin (Ro 10-1670).","2149914","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"23511242",2013,"Retinoic acid regulation of male meiosis.","23511242","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"23936463",2013,"Nanosecond pulsed electric field suppresses development of eyes and germ cells through blocking synthesis of retinoic acid in Medaka (Oryzias latipes).","23936463","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"2956134",1987,"Andrological investigations in patients treated with etretin.","2956134","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"3159708",1985,"[13-cis-Retinoic acid and spermatogenesis. Spermatological and impulse cytophotometric studies].","3159708","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",1,1,"3481225",1987,"Spermatological investigations in patients treated with etretinate and isotretinoin.","3481225","Tretinoin","Spermatozoa",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I4228,I4228)","v":"Tretinoin"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J4228,J4228)","v":"Spermatozoa"},0,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H4228,H4228)","v":"4459289"},1974,"Incorporation of labelled retinol and retinoic acid in bovine spermatozoa effect of zinc on the rate of incorporation.","4459289","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Spermatozoa",0,1,"6852307",1983,"[Effect of Tigason on the membrane of human spermatozoa (Rb+ uptake)].","6852307","Tretinoin","Spermatozoa",1,null,1]
["Tretinoin","Testis",0,1,"1062881",1975,"Aspects of teratology of vitamin A acid (beta-all-trans retinoic acid).","1062881","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"10837026",2000,"E-MAP-115, encoding a microtubule-associated protein, is a retinoic acid-inducible gene required for spermatogenesis.","10837026","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"14613895",2004,"Retinoic acid inhibits rat XY gonad development by blocking mesonephric cell migration and decreasing the number of gonocytes.","14613895","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"14960491",2004,"Retinoid-sensitive steps in steroidogenesis in fetal and neonatal rat testes: in vitro and in vivo studies.","14960491","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"1593535",1992,"Spermatogenesis in retinol-deficient rats maintained on retinoic acid.","1593535","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"16574820",2006,"Retinoid signaling determines germ cell fate in mice.","16574820","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"16621909",2006,"Use of organ culture to study the human fetal testis development: effect of retinoic acid.","16621909","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"17303670",2007,"Identification and distribution of a novel platelet-derived growth factor receptor beta variant: effect of retinoic acid and involvement in cell differentiation.","17303670","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"17332523",2007,"Utilization of DR1 as true RARE in regulating the Ssm, a novel retinoic acid-target gene in the mouse testis.","17332523","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"18158153",2008,"Retinoid requirements in the reproduction of zebrafish.","18158153","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"18256537",2008,"Retinoic acid prevents germ cell mitotic arrest in mouse fetal testes.","18256537","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"18322276",2008,"Expression of stimulated by retinoic acid gene 8 (Stra8) in spermatogenic cells induced by retinoic acid: an in vivo study in vitamin A-sufficient postnatal murine testes.","18322276","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"18799751",2008,"Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice.","18799751","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"19890016",2010,"Ethanol elevates physiological all-trans-retinoic acid levels in select loci through altering retinoid metabolism in multiple loci: a potential mechanism of ethanol toxicity.","19890016","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",1,1,"1996464",1991,"Time course of testicular degeneration in rats induced by a synthetic retinoid (Ro 23-2895) and evidence for induction of hypovitaminosis A in the testes.","1996464","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"20159962",2010,"Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells.","20159962","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"20650878",2010,"Retinoic acid availability drives the asynchronous initiation of spermatogonial differentiation in the mouse.","20650878","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"20705791",2011,"Suppression of spermatogenesis by bisdichloroacetyldiamines is mediated by inhibition of testicular retinoic acid biosynthesis.","20705791","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"20842651",2010,"The role of CYP26 enzymes in defining appropriate retinoic acid exposure during embryogenesis.","20842651","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"21674038",2011,"Retinoic Acid signalling and the control of meiotic entry in the human fetal gonad.","21674038","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"24056063",2013,"Retinoic acid homeostasis regulates meiotic entry in developing anuran gonads and in Bidder's organ through Raldh2 and Cyp26b1 proteins.","24056063","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"24161026",2013,"c-kit expression profile and regulatory factors during spermatogonial stem cell differentiation.","24161026","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"24478393",2014,"Retinoic acid induces multiple hallmarks of the prospermatogonia-to-spermatogonia transition in the neonatal mouse.","24478393","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"24711451",2014,"Inhibition of retinoic acid biosynthesis by the bisdichloroacetyldiamine WIN 18,446 markedly suppresses spermatogenesis and alters retinoid metabolism in mice.","24711451","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",1,1,"3744176",1986,"Effect of vitamin A acid on the testis of the Egyptian toad.","3744176","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"3857793",1985,"[Light microscopic studies of spermatogenesis in rats following the administration of a high dose of 13-cis-retinoic acid].","3857793","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"6129843",1982,"Etinoic acid (vitamin A acid) induces spermatogenesis in adult mouse cryptorchid testes in vitro.","6129843","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"6868728",1983,"[Effect of aromatic retinoid on spermatogenesis in rats. Light microscopy findings in the testes (including some other selected organs)].","6868728","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"7406530",1980,"[Reversible impairment of spermatogenesis induced by aromatic retinoid in guinea pigs (author's transl)].","7406530","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"8593792",1996,"All-trans-4-oxo-retinoic acid: a potent inducer of in vivo proliferation of growth-arrested A spermatogonia in the vitamin A-deficient mouse testis.","8593792","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"8797830",1996,"Molecular identification of a major retinoic-acid-synthesizing enzyme, a retinaldehyde-specific dehydrogenase.","8797830","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"8896602",1996,"Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acid-responsive gene.","8896602","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"9075714",1997,"Effect of retinoid status on the messenger ribonucleic acid expression of nuclear retinoid receptors alpha, beta, and gamma, and retinoid X receptors alpha, beta, and gamma in the mouse testis.","9075714","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"9496783",1998,"Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily.","9496783","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"9547504",1998,"Isolation and characterization of all-trans-retinoic acid-responsive genes in the rat testis.","9547504","Tretinoin","Testis",1,null,1]
["Tretinoin","Testis",0,1,"9751509",1998,"The effect of 9-cis-retinoic acid on proliferation and differentiation of a spermatogonia and retinoid receptor gene expression in the vitamin A-deficient mouse testis.","9751509","Tretinoin","Testis",1,null,1]
["Tretinoin","Urethra",1,1,"11795391",2001,"External genitalia formation: role of fibroblast growth factor, retinoic acid signaling, and distal urethral epithelium.","11795391","Tretinoin","Urethra",1,null,1]
["Tretinoin","Urethra",1,0,"14966734",2004,"Sonic hedgehog and bone morphogenetic protein 4 expressions in the hindgut region of murine embryos with anorectal malformations.","14966734","Tretinoin","Urethra",1,null,1]
["Tretinoin","Urogenital Abnormalities",1,1,"12598973",2002,"Relationship of the fistulas to the rectum and genitourinary tract in mouse fetuses with high anorectal malformations induced by all-trans retinoic acid.","12598973","Tretinoin","Urogenital Abnormalities",1,null,1]
["Tretinoin","Urogenital Abnormalities",0,1,"20409737",2010,"Anorectal and urinary anomalies and aberrant retinoic acid metabolism in cytochrome P450 oxidoreductase deficiency.","20409737","Tretinoin","Urogenital Abnormalities",1,null,1]
["Tretinoin","Urogenital Abnormalities",1,0,"8761883",1996,"Pattern of retinoid-induced teratogenic effects: possible relationship with relative selectivity for nuclear retinoid receptors RAR alpha, RAR beta, and RAR gamma.","8761883","Tretinoin","Urogenital Abnormalities",1,null,1]
["Tretinoin","Urogenital Abnormalities",1,1,"9535508",1998,"Retinoic acid-induced caudal regression syndrome in the mouse fetus.","9535508","Tretinoin","Urogenital Abnormalities",1,null,1]
["Tretinoin","Vas Deferens",1,1,"18085413",2008,"Exposure to 9-cis retinoic acid induces penis and vas deferens development in the female rock shell, Thais clavigera.","18085413","Tretinoin","Vas Deferens",1,null,1]
["triadimefon","Genitalia, Male",1,1,"17018648",2007,"Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat.","17018648","triadimefon","Genitalia, Male",1,null,1]
["triadimefon","Sperm Motility",1,1,"17018648",2007,"Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat.","17018648","triadimefon","Sperm Motility",1,null,1]
["triadimefon","Spermatozoa",1,1,"16863662",2006,"Toxic effects of two pesticides, Imazalil and Triadimefon, on the early development of the ascidian Phallusia mammillata (Chordata, Ascidiacea).","16863662","triadimefon","Spermatozoa",1,null,1]
["triadimefon","Spermatozoa",1,1,"17018648",2007,"Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat.","17018648","triadimefon","Spermatozoa",1,null,1]
["triadimefon","Testis",1,1,"19423681",2009,"Mode of action for reproductive and hepatic toxicity inferred from a genomic study of triazole antifungals.","19423681","triadimefon","Testis",1,null,1]
["Trichloroacetic Acid","Sperm Head",1,1,"3600687",1987,"Relative genotoxicity of trichloroacetic acid (TCA) as revealed by different cytogenetic assays: bone marrow chromosome aberration, micronucleus and sperm-head abnormality in the mouse.","3600687","Trichloroacetic Acid","Sperm Head",1,null,1]
["Trichloroacetic Acid","Spermatozoa",0,1,"5892197",1965,"Quantitative cytophotometric determination of nuclear proteins after alkylation.","5892197","Trichloroacetic Acid","Spermatozoa",1,null,1]
["triphenyltin hydroxide","Sperm Count",1,1,"16806747",2006,"Reduction of spermatogenesis and steroidogenesis in mice after fentin and fenbutatin administration.","16806747","triphenyltin hydroxide","Sperm Count",1,null,1]
["triphenyltin hydroxide","Sperm Motility",1,1,"16806747",2006,"Reduction of spermatogenesis and steroidogenesis in mice after fentin and fenbutatin administration.","16806747","triphenyltin hydroxide","Sperm Motility",1,null,1]
["triphenyltin hydroxide","Spermatogenesis",1,1,"16806747",2006,"Reduction of spermatogenesis and steroidogenesis in mice after fentin and fenbutatin administration.","16806747","triphenyltin hydroxide","Spermatogenesis",1,null,1]
["triphenyltin hydroxide","Testis",1,1,"16806747",2006,"Reduction of spermatogenesis and steroidogenesis in mice after fentin and fenbutatin administration.","16806747","triphenyltin hydroxide","Testis",1,null,1]
["vinclozolin","Blood-Testis Barrier",1,1,"17244729",2007,"Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice.","17244729","vinclozolin","Blood-Testis Barrier",1,null,1]
["vinclozolin","Cryptorchidism",1,1,"14966743",2004,"The effect of a prenatal androgen disruptor, vinclozolin, on gubernacular migration and testicular descent in rats.","14966743","vinclozolin","Cryptorchidism",1,null,1]
["vinclozolin","Cryptorchidism",1,1,"14966744",2004,"Short-time exposure to vinclozolin in utero induces testicular maldescent associated with a spinal nucleus alteration of the genitofemoral nerve in rats.","14966744","vinclozolin","Cryptorchidism",1,null,1]
["vinclozolin","Cryptorchidism",1,1,"17296284",2007,"Sequelae in male rabbits following developmental exposure to p,p'-DDT or a mixture of p,p'-DDT and vinclozolin: cryptorchidism, germ cell atypia, and sexual dysfunction.","17296284","vinclozolin","Cryptorchidism",1,null,1]
["vinclozolin","Disorders of Sex Development",1,1,"11759570",2001,"Effects of endocrine disruptors on prosobranch snails (Mollusca: Gastropoda) in the laboratory. Part III: Cyproterone acetate and vinclozolin as antiandrogens.","11759570","vinclozolin","Disorders of Sex Development",1,null,1]
["vinclozolin","Genitalia, Male",1,1,"10188191",1999,"Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat.","10188191","vinclozolin","Genitalia, Male",1,null,1]
["vinclozolin","Genitalia, Male",1,1,"10788570",2000,"Characterization of the period of sensitivity of fetal male sexual development to vinclozolin.","10788570","vinclozolin","Genitalia, Male",1,null,1]
["vinclozolin","Genitalia, Male",1,1,"11029267",2000,"Pre- and postnatal oral toxicity of vinclozolin in Wistar and Long-Evans rats.","11029267","vinclozolin","Genitalia, Male",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I4292,I4292)","v":"vinclozolin"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J4292,J4292)","v":"Genitalia, Male"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H4292,H4292)","v":"14966743"},2004,"The effect of a prenatal androgen disruptor, vinclozolin, on gubernacular migration and testicular descent in rats.","14966743","vinclozolin","Genitalia, Male",1,null,1]
["vinclozolin","Genitalia, Male",1,1,"14966744",2004,"Short-time exposure to vinclozolin in utero induces testicular maldescent associated with a spinal nucleus alteration of the genitofemoral nerve in rats.","14966744","vinclozolin","Genitalia, Male",1,null,1]
["vinclozolin","Genitalia, Male",1,1,"18940246",2008,"Effect of low dose of vinclozolin on reproductive tract development and sperm parameters in CD1 outbred mice.","18940246","vinclozolin","Genitalia, Male",1,null,1]
["vinclozolin","Genitalia, Male",1,1,"19711250",2009,"Epigenetic transgenerational effects of endocrine disruptors on male reproduction.","19711250","vinclozolin","Genitalia, Male",1,null,1]
["vinclozolin","Genitalia, Male",1,1,"23313085",2013,"Vinclozolin--no transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route.","23313085","vinclozolin","Genitalia, Male",1,null,1]
["vinclozolin","Hypospadias",1,1,"14966743",2004,"The effect of a prenatal androgen disruptor, vinclozolin, on gubernacular migration and testicular descent in rats.","14966743","vinclozolin","Hypospadias",1,null,1]
["vinclozolin","Hypospadias",1,1,"16504050",2006,"Embryonic exposure to the fungicide vinclozolin causes virilization of females and alteration of progesterone receptor expression in vivo: an experimental study in mice.","16504050","vinclozolin","Hypospadias",1,null,1]
["vinclozolin","Hypospadias",1,1,"17905137",2007,"Endocrine disruptors and hypospadias: role of genistein and the fungicide vinclozolin.","17905137","vinclozolin","Hypospadias",1,null,1]
["vinclozolin","Hypospadias",1,1,"23313085",2013,"Vinclozolin--no transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route.","23313085","vinclozolin","Hypospadias",1,null,1]
["vinclozolin","Penis",1,1,"14966743",2004,"The effect of a prenatal androgen disruptor, vinclozolin, on gubernacular migration and testicular descent in rats.","14966743","vinclozolin","Penis",1,null,1]
["vinclozolin","Penis",1,1,"16765025",2006,"Learning deficits expressed as delayed extinction of a conditioned running response following perinatal exposure to vinclozolin.","16765025","vinclozolin","Penis",1,null,1]
["vinclozolin","Prostate",1,1,"10188191",1999,"Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat.","10188191","vinclozolin","Prostate",1,null,1]
["vinclozolin","Prostate",0,1,"18220299",2008,"Transgenerational effects of the endocrine disruptor vinclozolin on the prostate transcriptome and adult onset disease.","18220299","vinclozolin","Prostate",1,null,1]
["vinclozolin","Prostate",1,1,"18629315",2008,"Early-onset endocrine disruptor-induced prostatitis in the rat.","18629315","vinclozolin","Prostate",1,null,1]
["vinclozolin","Prostate",0,1,"20056826",2010,"Vinclozolin exposure in utero induces postpubertal prostatitis and reduces sperm production via a reversible hormone-regulated mechanism.","20056826","vinclozolin","Prostate",1,null,1]
["vinclozolin","Prostate",1,1,"23041264",2012,"Epigenetic transgenerational inheritance of vinclozolin induced mouse adult onset disease and associated sperm epigenome biomarkers.","23041264","vinclozolin","Prostate",1,null,1]
["vinclozolin","Seminal Vesicles",1,1,"15297758",2004,"Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty.","15297758","vinclozolin","Seminal Vesicles",1,null,1]
["vinclozolin","Seminiferous Tubules",1,1,"15279874",2004,"Effect of the anti-androgenic endocrine disruptor vinclozolin on embryonic testis cord formation and postnatal testis development and function.","15279874","vinclozolin","Seminiferous Tubules",1,null,1]
["vinclozolin","Seminiferous Tubules",1,1,"16595731",2006,"Disruption of sexual function, FSH secretion, and spermiogenesis in rabbits following developmental exposure to vinclozolin, a fungicide.","16595731","vinclozolin","Seminiferous Tubules",1,null,1]
["vinclozolin","Seminiferous Tubules",1,1,"17244729",2007,"Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice.","17244729","vinclozolin","Seminiferous Tubules",1,null,1]
["vinclozolin","Sperm Count",1,1,"12930724",2003,"The effects of vinclozolin, an anti-androgenic fungicide, on male guppy secondary sex characters and reproductive success.","12930724","vinclozolin","Sperm Count",1,null,1]
["vinclozolin","Sperm Count",1,1,"15253051",2004,"Effects of vinclozolin on spermatogenesis and reproductive success in the Japanese quail (Coturnix coturnix japonica).","15253051","vinclozolin","Sperm Count",1,null,1]
["vinclozolin","Sperm Count",1,1,"15279874",2004,"Effect of the anti-androgenic endocrine disruptor vinclozolin on embryonic testis cord formation and postnatal testis development and function.","15279874","vinclozolin","Sperm Count",1,null,1]
["vinclozolin","Sperm Count",1,1,"15297758",2004,"Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty.","15297758","vinclozolin","Sperm Count",1,null,1]
["vinclozolin","Sperm Count",1,1,"18762243",2008,"Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.","18762243","vinclozolin","Sperm Count",1,null,1]
["vinclozolin","Sperm Count",1,1,"19672408",2009,"Chronic dietary exposure to a low-dose mixture of genistein and vinclozolin modifies the reproductive axis, testis transcriptome, and fertility.","19672408","vinclozolin","Sperm Count",1,null,1]
["vinclozolin","Sperm Count",1,1,"19887539",2010,"Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm.","19887539","vinclozolin","Sperm Count",1,null,1]
["vinclozolin","Sperm Count",1,1,"21172421",2011,"Antagonistic effects of gestational dietary exposure to low-dose vinclozolin and genistein on rat fetal germ cell development.","21172421","vinclozolin","Sperm Count",1,null,1]
["vinclozolin","Sperm Count",1,1,"23313085",2013,"Vinclozolin--no transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route.","23313085","vinclozolin","Sperm Count",1,null,1]
["vinclozolin","Sperm Motility",1,1,"15297758",2004,"Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty.","15297758","vinclozolin","Sperm Motility",1,null,1]
["vinclozolin","Sperm Motility",1,1,"18762243",2008,"Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.","18762243","vinclozolin","Sperm Motility",1,null,1]
["vinclozolin","Sperm Motility",1,1,"19672408",2009,"Chronic dietary exposure to a low-dose mixture of genistein and vinclozolin modifies the reproductive axis, testis transcriptome, and fertility.","19672408","vinclozolin","Sperm Motility",1,null,1]
["vinclozolin","Sperm Motility",1,1,"19887539",2010,"Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm.","19887539","vinclozolin","Sperm Motility",1,null,1]
["vinclozolin","Sperm Motility",1,1,"23041264",2012,"Epigenetic transgenerational inheritance of vinclozolin induced mouse adult onset disease and associated sperm epigenome biomarkers.","23041264","vinclozolin","Sperm Motility",1,null,1]
["vinclozolin","Sperm Motility",1,1,"23313085",2013,"Vinclozolin--no transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route.","23313085","vinclozolin","Sperm Motility",1,null,1]
["vinclozolin","Sperm Motility",1,1,"23376258",2013,"Influence of environmentally relevant concentrations of vinclozolin on quality, DNA integrity, and antioxidant responses of sterlet Acipenser ruthenus spermatozoa.","23376258","vinclozolin","Sperm Motility",1,null,1]
["vinclozolin","Spermatids",0,1,"20056826",2010,"Vinclozolin exposure in utero induces postpubertal prostatitis and reduces sperm production via a reversible hormone-regulated mechanism.","20056826","vinclozolin","Spermatids",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"14967917",2003,"Effects of vinclozolin administration on sperm production and testosterone biosynthetic pathway in adult male rat.","14967917","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"15253051",2004,"Effects of vinclozolin on spermatogenesis and reproductive success in the Japanese quail (Coturnix coturnix japonica).","15253051","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"15279874",2004,"Effect of the anti-androgenic endocrine disruptor vinclozolin on embryonic testis cord formation and postnatal testis development and function.","15279874","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"16595731",2006,"Disruption of sexual function, FSH secretion, and spermiogenesis in rabbits following developmental exposure to vinclozolin, a fungicide.","16595731","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",0,1,"16837734",2006,"Transgenerational effect of the endocrine disruptor vinclozolin on male spermatogenesis.","16837734","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"17244729",2007,"Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice.","17244729","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"17296284",2007,"Sequelae in male rabbits following developmental exposure to p,p'-DDT or a mixture of p,p'-DDT and vinclozolin: cryptorchidism, germ cell atypia, and sexual dysfunction.","17296284","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"18485663",2008,"Vinclozolin--the lack of a transgenerational effect after oral maternal exposure during organogenesis.","18485663","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"18762243",2008,"Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.","18762243","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"18940246",2008,"Effect of low dose of vinclozolin on reproductive tract development and sperm parameters in CD1 outbred mice.","18940246","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"19303894",2009,"Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.","19303894","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"19887539",2010,"Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm.","19887539","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",0,1,"21126777",2011,"Gene expression profiling of the androgen receptor antagonists flutamide and vinclozolin in zebrafish (Danio rerio) gonads.","21126777","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatogenesis",1,1,"24388192",2014,"Epigenetic effects of methoxychlor and vinclozolin on male gametes.","24388192","vinclozolin","Spermatogenesis",1,null,1]
["vinclozolin","Spermatozoa",1,1,"15279875",2004,"High-resolution image cytometry of rat sperm nuclear shape, size and chromatin status. Experimental validation with the reproductive toxicant vinclozolin.","15279875","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"15297758",2004,"Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty.","15297758","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"15933200",2005,"Epigenetic transgenerational actions of endocrine disruptors and male fertility.","15933200","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"16595731",2006,"Disruption of sexual function, FSH secretion, and spermiogenesis in rabbits following developmental exposure to vinclozolin, a fungicide.","16595731","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"17296284",2007,"Sequelae in male rabbits following developmental exposure to p,p'-DDT or a mixture of p,p'-DDT and vinclozolin: cryptorchidism, germ cell atypia, and sexual dysfunction.","17296284","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"18042343",2008,"Transgenerational epigenetic programming of the embryonic testis transcriptome.","18042343","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"18762243",2008,"Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.","18762243","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"19303894",2009,"Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.","19303894","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"19887539",2010,"Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm.","19887539","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"20616205",2010,"Modified expression of several sperm proteins after chronic exposure to the antiandrogenic compound vinclozolin.","20616205","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",0,1,"20927350",2010,"Epigenetic transgenerational actions of vinclozolin on promoter regions of the sperm epigenome.","20927350","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"21172421",2011,"Antagonistic effects of gestational dietary exposure to low-dose vinclozolin and genistein on rat fetal germ cell development.","21172421","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"22819807",2012,"Anti-androgen vinclozolin impairs sperm quality and steroidogenesis in goldfish.","22819807","vinclozolin","Spermatozoa",1,null,1]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & I4356,I4356)","v":"vinclozolin"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & J4356,J4356)","v":"Spermatozoa"},1,1,{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & H4356,H4356)","v":"23376258"},2013,"Influence of environmentally relevant concentrations of vinclozolin on quality, DNA integrity, and antioxidant responses of sterlet Acipenser ruthenus spermatozoa.","23376258","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Spermatozoa",1,1,"24388192",2014,"Epigenetic effects of methoxychlor and vinclozolin on male gametes.","24388192","vinclozolin","Spermatozoa",1,null,1]
["vinclozolin","Testis",1,1,"10788570",2000,"Characterization of the period of sensitivity of fetal male sexual development to vinclozolin.","10788570","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"11985887",2002,"Comparison of antiandrogenic activities of vinclozolin and D,L-camphorquinone in androgen receptor gene transcription assay in vitro and mouse in utero exposure assay in vivo.","11985887","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"12758004",2003,"Effects of the antiandrogens, vinclozolin and cyproterone acetate on gonadal development in the Japanese medaka (Oryzias latipes).","12758004","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"14966743",2004,"The effect of a prenatal androgen disruptor, vinclozolin, on gubernacular migration and testicular descent in rats.","14966743","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"14966744",2004,"Short-time exposure to vinclozolin in utero induces testicular maldescent associated with a spinal nucleus alteration of the genitofemoral nerve in rats.","14966744","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"14967917",2003,"Effects of vinclozolin administration on sperm production and testosterone biosynthetic pathway in adult male rat.","14967917","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"15253051",2004,"Effects of vinclozolin on spermatogenesis and reproductive success in the Japanese quail (Coturnix coturnix japonica).","15253051","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"15279874",2004,"Effect of the anti-androgenic endocrine disruptor vinclozolin on embryonic testis cord formation and postnatal testis development and function.","15279874","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"15297758",2004,"Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty.","15297758","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",0,1,"16837734",2006,"Transgenerational effect of the endocrine disruptor vinclozolin on male spermatogenesis.","16837734","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"17296284",2007,"Sequelae in male rabbits following developmental exposure to p,p'-DDT or a mixture of p,p'-DDT and vinclozolin: cryptorchidism, germ cell atypia, and sexual dysfunction.","17296284","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"18042343",2008,"Transgenerational epigenetic programming of the embryonic testis transcriptome.","18042343","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"18348629",2008,"Reproductive toxicity of vinclozolin in the fathead minnow: confirming an anti-androgenic mode of action.","18348629","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"18485663",2008,"Vinclozolin--the lack of a transgenerational effect after oral maternal exposure during organogenesis.","18485663","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"18762243",2008,"Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.","18762243","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"18940246",2008,"Effect of low dose of vinclozolin on reproductive tract development and sperm parameters in CD1 outbred mice.","18940246","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"19303894",2009,"Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.","19303894","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"19672408",2009,"Chronic dietary exposure to a low-dose mixture of genistein and vinclozolin modifies the reproductive axis, testis transcriptome, and fertility.","19672408","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",0,1,"20056826",2010,"Vinclozolin exposure in utero induces postpubertal prostatitis and reduces sperm production via a reversible hormone-regulated mechanism.","20056826","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"20566332",2010,"Alterations in the developing testis transcriptome following embryonic vinclozolin exposure.","20566332","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"20616205",2010,"Modified expression of several sperm proteins after chronic exposure to the antiandrogenic compound vinclozolin.","20616205","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",0,1,"21126777",2011,"Gene expression profiling of the androgen receptor antagonists flutamide and vinclozolin in zebrafish (Danio rerio) gonads.","21126777","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"21172421",2011,"Antagonistic effects of gestational dietary exposure to low-dose vinclozolin and genistein on rat fetal germ cell development.","21172421","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"22819807",2012,"Anti-androgen vinclozolin impairs sperm quality and steroidogenesis in goldfish.","22819807","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"23041264",2012,"Epigenetic transgenerational inheritance of vinclozolin induced mouse adult onset disease and associated sperm epigenome biomarkers.","23041264","vinclozolin","Testis",1,null,1]
["vinclozolin","Testis",1,1,"24995616",2014,"Alternations in neuroendocrine and endocrine regulation of reproduction in male goldfish (Carassius auratus) following an acute and chronic exposure to vinclozolin, in vivo.","24995616","vinclozolin","Testis",1,null,1]
["vinclozolin","Urethra",1,1,"16504050",2006,"Embryonic exposure to the fungicide vinclozolin causes virilization of females and alteration of progesterone receptor expression in vivo: an experimental study in mice.","16504050","vinclozolin","Urethra",1,null,1]
["Ziram","Spermatogonia",1,1,"3367929",1988,"Cytogenetic effects of Cuman L, a dithiocarbamate fungicide.","3367929","Ziram","Spermatogonia",1,null,1]
["Ziram","Spermatozoa",1,1,"3367929",1988,"Cytogenetic effects of Cuman L, a dithiocarbamate fungicide.","3367929","Ziram","Spermatozoa",1,null,1]
["Ziram","Testis",1,1,"6230523",1983,"Decreased fertility, increased dominant lethals, skeletal malformations induced in the mouse by Ziram fungicide.","6230523","Ziram","Testis",1,null,1]

{"sheet":"CuratedList","index":3,"n_rows":155,"n_cols":8,"rows_kept":155,"cut":false,"hidden":false,"merged":[]}
["Curated List "]
["Chemical (hyperlinked)","Disease/condition (hyperlinked)","PMID","Pub Yr","Title","LinkPMID","LinkName","Disease/condition"]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & G3,G3)","v":"Acetaminophen"},{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & H3,H3)","v":"Cryptorchidism"},{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & F3,F3)","v":20805751},2010,"Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism.",20805751,"Acetaminophen","Cryptorchidism"]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & G4,G4)","v":"Acetaminophen"},"Cryptorchidism",{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & F4,F4)","v":22612476},2012,"Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.",22612476,"Acetaminophen","Cryptorchidism"]
["Acetaminophen","Cryptorchidism",24030937,2013,"Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.",24030937,"Acetaminophen","Cryptorchidism"]
["Acetaminophen","Hypospadias",15283825,2004,"Evaluation of adding preoperative or postoperative rectal paracetamol to caudal bupivacaine for postoperative analgesia in children.",15283825,"Acetaminophen","Hypospadias"]
["Aspirin","Cryptorchidism",20805751,2010,"Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism.",20805751,"Aspirin","Cryptorchidism"]
["Aspirin","Cryptorchidism",22612476,2012,"Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.",22612476,"Aspirin","Cryptorchidism"]
["Aspirin","Cryptorchidism",24030937,2013,"Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.",24030937,"Aspirin","Cryptorchidism"]
["Atrazine","Hypospadias",17926863,2007,"[The establishment of hypospadias rat model and embryoteratogenic test of Atrazine].",17926863,"Atrazine","Hypospadias"]
["bisphenol A","Cryptorchidism",23285176,2012,"Individual variation of the genetic response to bisphenol a in human foreskin fibroblast cells derived from cryptorchidism and hypospadias patients.",23285176,"bisphenol A","Cryptorchidism"]
["bisphenol A","Cryptorchidism",23796010,2013,"Bisphenol A: an endocrine and metabolic disruptor.",23796010,"bisphenol A","Cryptorchidism"]
["bisphenol A","Hypospadias",22574217,2012,"Identification of novel low-dose bisphenol a targets in human foreskin fibroblast cells derived from hypospadias patients.",22574217,"bisphenol A","Hypospadias"]
["bisphenol A","Hypospadias",23285176,2012,"Individual variation of the genetic response to bisphenol a in human foreskin fibroblast cells derived from cryptorchidism and hypospadias patients.",23285176,"bisphenol A","Hypospadias"]
["Chlorpromazine","Urogenital Abnormalities",4945875,1971,"[Teratogenic effects of hyperemesis gravidarum and of the customary drugs used in its therapy].",4945875,"Chlorpromazine","Urogenital Abnormalities"]
["Dibutyl Phthalate","Cryptorchidism",10198273,1999,"Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.",10198273,"Dibutyl Phthalate","Cryptorchidism"]
["Dibutyl Phthalate","Cryptorchidism",10643872,2000,"Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy.",10643872,"Dibutyl Phthalate","Cryptorchidism"]
["Dibutyl Phthalate","Cryptorchidism",11297877,2001,"Adverse effects on development of the reproductive system in male offspring of rats given monobutyl phthalate, a metabolite of dibutyl phthalate, during late pregnancy.",11297877,"Dibutyl Phthalate","Cryptorchidism"]
["Dibutyl Phthalate","Cryptorchidism",14978965,2003,"[Effects of prenatal exposure to phthalate ester on both testicular descent and urogenital development in rats].",14978965,"Dibutyl Phthalate","Cryptorchidism"]
["Dibutyl Phthalate","Cryptorchidism",16037377,2005,"Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate.",16037377,"Dibutyl Phthalate","Cryptorchidism"]
["Dibutyl Phthalate","Cryptorchidism",18621746,2008,"The orl rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure.",18621746,"Dibutyl Phthalate","Cryptorchidism"]
["Dibutyl Phthalate","Cryptorchidism",20954080,2010,"Effects of in utero exposure to DI(n-Butyl) phthalate on development of male reproductive tracts in Sprague-Dawley rats.",20954080,"Dibutyl Phthalate","Cryptorchidism"]
["Dibutyl Phthalate","Cryptorchidism",22864157,2012,"New Zealand Malayan war veterans' exposure to dibutylphthalate is associated with an increased incidence of cryptorchidism, hypospadias and breast cancer in their children.",22864157,"Dibutyl Phthalate","Cryptorchidism"]
["Dibutyl Phthalate","Hypospadias",14978965,2003,"[Effects of prenatal exposure to phthalate ester on both testicular descent and urogenital development in rats].",14978965,"Dibutyl Phthalate","Hypospadias"]
["Dibutyl Phthalate","Hypospadias",17343970,2007,"Study on developmental abnormalities in hypospadiac male rats induced by maternal exposure to di-n-butyl phthalate (DBP).",17343970,"Dibutyl Phthalate","Hypospadias"]
["Dibutyl Phthalate","Hypospadias",19464577,2009,"Molecular and toxicologic research in newborn hypospadiac male rats following in utero exposure to di-n-butyl phthalate (DBP).",19464577,"Dibutyl Phthalate","Hypospadias"]
["Dibutyl Phthalate","Hypospadias",20954080,2010,"Effects of in utero exposure to DI(n-Butyl) phthalate on development of male reproductive tracts in Sprague-Dawley rats.",20954080,"Dibutyl Phthalate","Hypospadias"]
["Dibutyl Phthalate","Hypospadias",22273727,2012,"The role of androgen-induced growth factor (FGF8) on genital tubercle development in a hypospadiac male rat model of prenatal exposure to di-n-butyl phthalate.",22273727,"Dibutyl Phthalate","Hypospadias"]
["Dibutyl Phthalate","Hypospadias",22864157,2012,"New Zealand Malayan war veterans' exposure to dibutylphthalate is associated with an increased incidence of cryptorchidism, hypospadias and breast cancer in their children.",22864157,"Dibutyl Phthalate","Hypospadias"]
["Dibutyl Phthalate","Urogenital Abnormalities",12851105,2003,"Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to Di(n-butyl) phthalate.",12851105,"Dibutyl Phthalate","Urogenital Abnormalities"]
["Dichlorodiphenyl Dichloroethylene","Cryptorchidism",18503055,2008,"Cryptorchidism at birth in Nice area (France) is associated with higher prenatal exposure to PCBs and DDE, as assessed by colostrum concentrations.",18503055,"Dichlorodiphenyl Dichloroethylene","Cryptorchidism"]
["Dichlorodiphenyl Dichloroethylene","Urogenital Abnormalities",17272288,2007,"In utero exposure to the antiandrogen 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) in relation to anogenital distance in male newborns from Chiapas, México.",17272288,"Dichlorodiphenyl Dichloroethylene","Urogenital Abnormalities"]
["Diethylhexyl Phthalate","Cryptorchidism",21752447,2011,"In vitro effects of estradiol-17?, monobutyl phthalate and mono-(2-ethylhexyl) phthalate on the secretion of testosterone and insulin-like peptide 3 by interstitial cells of scrotal and retained testes in dogs.",21752447,"Diethylhexyl Phthalate","Cryptorchidism"]
["Diethylhexyl Phthalate","Hypospadias",18686198,2008,"Di(2-ethylhexyl) phthalate (DEHP) increases transforming growth factor-beta1 expression in fetal mouse genital tubercles.",18686198,"Diethylhexyl Phthalate","Hypospadias"]
["Diethylhexyl Phthalate","Hypospadias",19096195,2009,"Di-(2-ethylhexyl) phthalate upregulates ATF3 expression and suppresses apoptosis in mouse genital tubercle.",19096195,"Diethylhexyl Phthalate","Hypospadias"]
["Diethylhexyl Phthalate","Hypospadias",23228707,2013,"Dose-related effect by maternal exposure to di-(2-ethylhexyl) phthalate plasticizer on inducing hypospadiac male rats.",23228707,"Diethylhexyl Phthalate","Hypospadias"]
["Diethylstilbestrol","Cryptorchidism",10650968,2000,"Involvement of insulin-like factor 3 (Insl3) in diethylstilbestrol-induced cryptorchidism.",10650968,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",12638168,2003,"[A review of epidemiological studies about the incidence and etiological factors of cryptorchidism--relevance to endocrine-disrupting chemicals].",12638168,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",14130828,1964,"THE HORMONES AND PUBERTY.",14130828,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",14781,1977,"Induction of urogenital anomalies and some tumors in the progeny of mice receiving diethylstilbestrol during pregnancy.",14781,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",16020417,2005,"The health effects of diethylstilbestrol revisited.",16020417,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",19493424,2009,"Prenatal exposure to diaethylstilbestrol in the rat inhibits transabdominal testicular descent with involvement of the INSL3/LGR8 system and HOXA10.",19493424,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",19534997,2009,"[The effect of diethylstilbestrol on inducing abdominal cryptorchidism and relevant genetic expression in rats].",19534997,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",19689815,2009,"Urogenital abnormalities in men exposed to diethylstilbestrol in utero: a cohort study.",19689815,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",22945456,2012,"Diethylstilbestrol impairs the morphology and function of mouse gubernaculum testis in culture.",22945456,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",242076,1975,"Reproductive tract lesions in male mice exposed prenatally to diethylstilbestrol.",242076,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",37020,1979,"Physician advisory: health effects of the pregnancy use of diethylstilbestrol.",37020,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",37351,1979,"Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities.",37351,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",41978,1979,"Plasma testosterone concentrations in normal and estrogen treated mice of three strains differing in susceptibility to induction of Leydig cell tumors.",41978,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",4389146,1969,"Effect of diethylstilbestrol on enzymes of cryptochid mouse testes of Balb-c mice.",4389146,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",4390313,1969,"A histochemical study of the effect of estrogen on oxidative enzymes in the testes of cryptorchid BALB/c mice.",4390313,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",4399709,1970,"Changes in testicular DNA produced in BALB-c mice by diethylstilbestrol.",4399709,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",4404717,1972,"[Mechanism of action of testosterone on the gonads of male rats treated with stilbestrol].",4404717,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",6113570,1981,"Screening of adolescents exposed to diethylstilbestrol in utero.",6113570,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",6113890,1981,"Effects of cryptorchidy, parabiosis, and estrogen administration upon Leydig cell tumorigenesis in Fischer rats.",6113890,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",6121486,1982,"In utero exposure to diethylstilbestrol: adverse effects on the reproductive tract and reproductive performance and male and female offspring.",6121486,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Cryptorchidism",9472934,1998,"Effects of neonatal administration of diethylstilbestrol in male hamsters: disruption of reproductive function in adults after apparently normal pubertal development.",9472934,"Diethylstilbestrol","Cryptorchidism"]
["Diethylstilbestrol","Hypospadias",11748570,2002,"Characterization of diethylstilbestrol-induced hypospadias in female mice.",11748570,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Hypospadias",11943252,2002,"Iatrogenic legacy from diethylstilbestrol exposure.",11943252,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Hypospadias",11943257,2002,"Hypospadias in sons of women exposed to diethylstilbestrol in utero: a cohort study.",11943257,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Hypospadias",15906411,2005,"Hypospadias in sons of women exposed to diethylstilbestrol in utero.",15906411,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Hypospadias",15951681,2005,"Hypospadias in sons of women exposed to diethylstilbestrol in utero.",15951681,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Hypospadias",16293648,2006,"Hypospadias: a transgenerational effect of diethylstilbestrol?",16293648,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Hypospadias",16302166,2005,"Hypospadias in sons of women exposed to ditheylstilbestrol: a true trans-generational effect?",16302166,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Hypospadias",21458804,2011,"Prevalence of hypospadias in grandsons of women exposed to diethylstilbestrol during pregnancy: a multigenerational national cohort study.",21458804,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Hypospadias",454458,1979,"Teratogenesis and carcinogenesis in rat offspring after transplacental and transmammary exposure to diethylstilbestrol.",454458,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Hypospadias",6645389,1983,"Radiologic diagnosis of diethylstilbestrol induced teratogenesis in rats.",6645389,"Diethylstilbestrol","Hypospadias"]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & G68,G68)","v":"Diethylstilbestrol"},"Hypospadias",{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & F68,F68)","v":6740514},1984,"Direct fetal injections of diethylstilbestrol and 17 beta-estradiol: a method for investigating their teratogenicity.",6740514,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Hypospadias",972792,1976,"Urogenital tract abnormalities in sons of women treated with diethylstilbestrol.",972792,"Diethylstilbestrol","Hypospadias"]
["Diethylstilbestrol","Urogenital Abnormalities",12611468,2002,"Environmental estrogens: roles in male reproductive tract problems and in breast cancer.",12611468,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",14781,1977,"Induction of urogenital anomalies and some tumors in the progeny of mice receiving diethylstilbestrol during pregnancy.",14781,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",15856964,2005,"Pregnant \"DES daughters\" and their offspring.",15856964,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",19689815,2009,"Urogenital abnormalities in men exposed to diethylstilbestrol in utero: a cohort study.",19689815,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",376358,1979,"Fertility of the diethylstilbestrol-exposed offspring.",376358,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",398263,1979,"The effects of exogenous female hormones on the fetus.",398263,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",454458,1979,"Teratogenesis and carcinogenesis in rat offspring after transplacental and transmammary exposure to diethylstilbestrol.",454458,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",4979275,1969,"[Action of diethylstilbestrol on the hybrid from the crossBarbariedrake x Khaki Campbellduck].",4979275,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",6502859,1984,"Males exposed in utero to diethylstilbestrol.",6502859,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",6645389,1983,"Radiologic diagnosis of diethylstilbestrol induced teratogenesis in rats.",6645389,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",6772904,1980,"Carcinogenic and teratogenic activities of diethylstilbestrol in mice.",6772904,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",7035598,1981,"Randomised trial of high doses of stilboestrol and ethisterone therapy in pregnancy: long-term follow-up of the children.",7035598,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",7455920,1980,"Reproductive tract anomalies in mice after prenatal exposure to DES.",7455920,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",7717601,1995,"Diethylstilbestrol revisited: a review of the long-term health effects.",7717601,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",846001,1977,"Prenatal exposure to diethylstilbestrol in mice: toxicological studies.",846001,"Diethylstilbestrol","Urogenital Abnormalities"]
["Diethylstilbestrol","Urogenital Abnormalities",972792,1976,"Urogenital tract abnormalities in sons of women treated with diethylstilbestrol.",972792,"Diethylstilbestrol","Urogenital Abnormalities"]
["Estradiol","Cryptorchidism",10926772,2000,"A molecular basis for estrogen-induced cryptorchidism.",10926772,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",11025750,2000,"Elevated placental estradiol: a possible etiological factor of human cryptorchidism.",11025750,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",11025751,2000,"Excess fetal estrogen as an etiological cause of human cryptorchidism.",11025751,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",12722,1976,"[Effect of neonatal injections of estradiol, testosterone and cryproterone acetate on plasma and testicular testosterone and on the genital system in adult male mice].",12722,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",14263903,1964,"[EFFECT OF A SINGLE DOSE OF ESTRADIOL BENZOATE ADMINISTERED BEFORE THE 5TH DAY OF LIFE ON THE GENITAL TRACT OF THE RAT].",14263903,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",14289090,1964,"[CONGENITAL CRYPTORCHISM INDUCED BY ESTROGEN INJECTION INTO THE PREGNANT MOUSE].",14289090,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",21752447,2011,"In vitro effects of estradiol-17?, monobutyl phthalate and mono-(2-ethylhexyl) phthalate on the secretion of testosterone and insulin-like peptide 3 by interstitial cells of scrotal and retained testes in dogs.",21752447,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",23469656,2013,"[Establishment of cryptorchid infertile models by postnatal injection of estradiol in mice].",23469656,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",2570718,1989,"AVP receptors of mouse Leydig cells are regulated by LH and E2 and influenced by experimental cryptorchidism.",2570718,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",4152351,1973,"[Growth and structure of cryptorchid testes in mice born of mothers treated by oestradiol during pregnancy (author's transl)].",4152351,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",4387385,1968,"[Genital malformations induced in adult mice by a prenatal estrogenic action. I. The male (male pseudo-hermaphroditism)].",4387385,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",4405594,1972,"[Comparative study of changes in gonadotropic cells and testis in male rats treated with estrogens during the neonatal period].",4405594,"Estradiol","Cryptorchidism"]
["Estradiol","Cryptorchidism",6111879,1980,"Transmission and scanning electron microscopy of epididymis in male mice receiving estrogen during gestation.",6111879,"Estradiol","Cryptorchidism"]
["Estradiol","Hypospadias",14263903,1964,"[EFFECT OF A SINGLE DOSE OF ESTRADIOL BENZOATE ADMINISTERED BEFORE THE 5TH DAY OF LIFE ON THE GENITAL TRACT OF THE RAT].",14263903,"Estradiol","Hypospadias"]
["Estradiol","Hypospadias",17169275,2006,"Embryonic exposure to low-dose 17beta-estradiol decreases fetal mass sex specifically in male mice and does not cause hypospadias.",17169275,"Estradiol","Hypospadias"]
["Estradiol","Hypospadias",17302024,2007,"[Establishment of a mouse model of hypospadias induced by estradiol benzoate].",17302024,"Estradiol","Hypospadias"]
["Estradiol","Hypospadias",18001166,2007,"Estradiol upregulates activating transcription factor 3, a candidate gene in the etiology of hypospadias.",18001166,"Estradiol","Hypospadias"]
["Estradiol","Hypospadias",20180416,2009,"[Expressions of ATF3 and CTGF and their regulation by estradiol in the prepuce of hypospadias patients].",20180416,"Estradiol","Hypospadias"]
["Estradiol","Hypospadias",21676446,2011,"Polymorphisms in the P450 c17 (17-hydroxylase/17, 20-Lyase) gene: association with estradiol and testosterone concentration in hypospadias.",21676446,"Estradiol","Hypospadias"]
["Estradiol","Hypospadias",5463881,1970,"[Hypospadias induced by hormone therapy?].",5463881,"Estradiol","Hypospadias"]
["Estradiol","Hypospadias",5654606,1968,"Abnormalities in the adult mouse vagina after neonatal estradiol treatment.",5654606,"Estradiol","Hypospadias"]
["Estradiol","Hypospadias",5688816,1968,"Production of congenital adrenocortical hyperplasia in rats by estradiol-17-beta and inhibition of 3-beta-hydroxysteroid dehydrogenase.",5688816,"Estradiol","Hypospadias"]
["Estradiol","Hypospadias",5753098,1968,"[Genital malformations in adult mice resulting from prenatal estrogenic action. II. The female].",5753098,"Estradiol","Hypospadias"]
["Estradiol","Hypospadias",6740514,1984,"Direct fetal injections of diethylstilbestrol and 17 beta-estradiol: a method for investigating their teratogenicity.",6740514,"Estradiol","Hypospadias"]
["Estradiol","Urogenital Abnormalities",4975498,1969,"[On an anomaly of genital canals observed in Greek tortoise (Testudo graeca L.) embryos treated by estradiol benzoate].",4975498,"Estradiol","Urogenital Abnormalities"]
["Ethinyl Estradiol","Cryptorchidism",14130828,1964,"THE HORMONES AND PUBERTY.",14130828,"Ethinyl Estradiol","Cryptorchidism"]
["Ethinyl Estradiol","Cryptorchidism",1977467,1990,"The effect of in utero ethinyl oestradiol exposure on the risk of cryptorchid testis and testicular teratoma in mice.",1977467,"Ethinyl Estradiol","Cryptorchidism"]
["Ethinyl Estradiol","Cryptorchidism",2874623,1986,"Leydig cell hyperplasia in fetal mice treated transplacentally with ethinyl estradiol.",2874623,"Ethinyl Estradiol","Cryptorchidism"]
["Ethinyl Estradiol","Cryptorchidism",2876659,1986,"Accelerated differentiation in seminiferous tubules of fetal mice prenatally exposed to ethinyl estradiol.",2876659,"Ethinyl Estradiol","Cryptorchidism"]
["Ethinyl Estradiol","Hypospadias",16569931,2006,"Activating transcription factor 3 is estrogen-responsive in utero and upregulated during sexual differentiation.",16569931,"Ethinyl Estradiol","Hypospadias"]
["Ethinyl Estradiol","Hypospadias",16945680,2006,"Ontogeny of androgen receptor and disruption of its mRNA expression by exogenous estrogens during morphogenesis of the genital tubercle.",16945680,"Ethinyl Estradiol","Hypospadias"]
["Flutamide","Cryptorchidism",10198273,1999,"Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.",10198273,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",11057551,2000,"Comparative studies of fertility and histologic development of contralateral scrotal testes in two rat models of unilateral cryptorchidism.",11057551,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",11315278,2001,"The biological effect of phthalate esters on transabdominal migration of the testis in fetal rats in comparison with the antiandrogen flutamide.",11315278,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",1356753,1992,"Reversal of flutamide-induced cryptorchidism by prenatal time-specific androgens.",1356753,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",1364084,1992,"Disturbed testicular descent in the rat after prenatal exposure to the antiandrogen flutamide.",1364084,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",15729007,2004,"Effects of flutamide on sex maturation and behavior of offspring born to female rats treated during late pregnancy.",15729007,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",15750944,2005,"Gubernacular cell division in different rodent models of cryptorchidism supports indirect androgenic action via the genitofemoral nerve.",15750944,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",15788718,2005,"Changes in androgen-mediated reproductive development in male rat offspring following exposure to a single oral dose of flutamide at different gestational ages.",15788718,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",16608089,2006,"[Impact of flutamide on sex differentiation in rats].",16608089,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",1677329,1991,"Effects of flutamide and finasteride on rat testicular descent.",1677329,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",1678699,1991,"Time-specific androgen blockade with flutamide inhibits testicular descent in the rat.",1678699,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",20006020,2009,"The antiandrogen flutamide perturbs inguinoscrotal testicular descent in the rat and suggests a link with mammary development.",20006020,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",21485540,2011,"[Establishment of a rat model of flutamide-induced cryptorchidism with remaining gonocytes].",21485540,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",22007488,2011,"[The regulation of T3 on maldeveloped gonocyte (Go) and expression of NCAM in flutamide-induced cryptorchidism rat].",22007488,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",22152882,2011,"The effect of flutamide on expression of androgen and estrogen receptors in the gubernaculum and surrounding structures during testicular descent.",22152882,"Flutamide","Cryptorchidism"]
[{"$f":"HYPERLINK(\"http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term=\" & G132,G132)","v":"Flutamide"},"Cryptorchidism",{"$f":"HYPERLINK(\"http://www.ncbi.nlm.nih.gov/pubmed/\" & F132,F132)","v":22152883},2011,"Gone with the Wnt: the canonical Wnt signaling axis is present and androgen dependent in the rodent gubernaculum.",22152883,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",7571228,1995,"Flutamide-induced cryptorchidism in the rat is associated with altered gubernacular morphology.",7571228,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",7609135,1995,"Antiandrogen induced cryptorchidism in the pig is associated with failed gubernacular regression and epididymal malformations.",7609135,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",7912741,1994,"Capsaicin increases the frequency of cryptorchidism in flutamide-treated rats.",7912741,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",7915761,1994,"Prenatal androgen blockade with flutamide inhibits masculinization of the genitofemoral nerve and testicular descent.",7915761,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",7915762,1994,"The effect of flutamide on testicular descent in rats examined by scanning electron microscopy.",7915762,"Flutamide","Cryptorchidism"]
["Flutamide","Cryptorchidism",9183680,1997,"The effects of pre- and postnatal exposure to the nonsteroidal antiandrogen flutamide on testis descent and morphology in the Albino Swiss rat.",9183680,"Flutamide","Cryptorchidism"]
["Flutamide","Hypospadias",14725615,2004,"Valproic acid is known to cause hypospadias in man but does not reduce anogenital distance or causes hypospadias in rats.",14725615,"Flutamide","Hypospadias"]
["Flutamide","Hypospadias",15080058,2004,"[A mouse model of hypospadias induced by flutamide].",15080058,"Flutamide","Hypospadias"]
["Flutamide","Hypospadias",15729007,2004,"Effects of flutamide on sex maturation and behavior of offspring born to female rats treated during late pregnancy.",15729007,"Flutamide","Hypospadias"]
["Flutamide","Hypospadias",16608089,2006,"[Impact of flutamide on sex differentiation in rats].",16608089,"Flutamide","Hypospadias"]
["Flutamide","Hypospadias",8789411,1995,"Effects of short-term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice.",8789411,"Flutamide","Hypospadias"]
["Propylthiouracil","Cryptorchidism",17033216,2006,"Effects of propylthiouracil on testicular tissue in undescended testes of newborn rats.",17033216,"Propylthiouracil","Cryptorchidism"]
["Tretinoin","Urogenital Abnormalities",12598973,2002,"Relationship of the fistulas to the rectum and genitourinary tract in mouse fetuses with high anorectal malformations induced by all-trans retinoic acid.",12598973,"Tretinoin","Urogenital Abnormalities"]
["Tretinoin","Urogenital Abnormalities",20409737,2010,"Anorectal and urinary anomalies and aberrant retinoic acid metabolism in cytochrome P450 oxidoreductase deficiency.",20409737,"Tretinoin","Urogenital Abnormalities"]
["Tretinoin","Urogenital Abnormalities",8761883,1996,"Pattern of retinoid-induced teratogenic effects: possible relationship with relative selectivity for nuclear retinoid receptors RAR alpha, RAR beta, and RAR gamma.",8761883,"Tretinoin","Urogenital Abnormalities"]
["Tretinoin","Urogenital Abnormalities",9535508,1998,"Retinoic acid-induced caudal regression syndrome in the mouse fetus.",9535508,"Tretinoin","Urogenital Abnormalities"]
["vinclozolin","Cryptorchidism",14966743,2004,"The effect of a prenatal androgen disruptor, vinclozolin, on gubernacular migration and testicular descent in rats.",14966743,"vinclozolin","Cryptorchidism"]
["vinclozolin","Cryptorchidism",14966744,2004,"Short-time exposure to vinclozolin in utero induces testicular maldescent associated with a spinal nucleus alteration of the genitofemoral nerve in rats.",14966744,"vinclozolin","Cryptorchidism"]
["vinclozolin","Cryptorchidism",17296284,2007,"Sequelae in male rabbits following developmental exposure to p,p'-DDT or a mixture of p,p'-DDT and vinclozolin: cryptorchidism, germ cell atypia, and sexual dysfunction.",17296284,"vinclozolin","Cryptorchidism"]
["vinclozolin","Hypospadias",14966743,2004,"The effect of a prenatal androgen disruptor, vinclozolin, on gubernacular migration and testicular descent in rats.",14966743,"vinclozolin","Hypospadias"]
["vinclozolin","Hypospadias",16504050,2006,"Embryonic exposure to the fungicide vinclozolin causes virilization of females and alteration of progesterone receptor expression in vivo: an experimental study in mice.",16504050,"vinclozolin","Hypospadias"]
["vinclozolin","Hypospadias",17905137,2007,"Endocrine disruptors and hypospadias: role of genistein and the fungicide vinclozolin.",17905137,"vinclozolin","Hypospadias"]
["vinclozolin","Hypospadias",23313085,2013,"Vinclozolin--no transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route.",23313085,"vinclozolin","Hypospadias"]